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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Somatostatin receptor type 1
Species	Rattus norvegicus (Rat)
Gene	Sstr1
Synonym	SRIF-2 SS-1-R SS1-R SS1R SST1 receptor
Disease	N/A for non-human GPCRs
Length	391
Amino acid sequence	MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCASRISTL
UniProt	P28646
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4652
IUPHAR	355
DrugBank	N/A

Ligand

Name	CHEMBL252029
Molecular formula	C26H29N5O3
IUPAC name	[(6aR,9R,10aR)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl]-[4-(4-nitrophenyl)piperazin-1-yl]methanone
Molecular weight	459.55
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.3
Synonyms	BDBM50423486
Inchi Key	JYURLFGIJFZTQW-IHLLOCCUSA-N
Inchi ID	InChI=1S/C26H29N5O3/c1-28-16-18(13-22-21-3-2-4-23-25(21)17(15-27-23)14-24(22)28)26(32)30-11-9-29(10-12-30)19-5-7-20(8-6-19)31(33)34/h2-8,15,18,22,24,27H,9-14,16H2,1H3/t18-,22-,24-/m1/s1
PubChem CID	44447062
ChEMBL	CHEMBL252029
IUPHAR	N/A
BindingDB	50423486
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Kd	3.89 nM	PMID18162395	ChEMBL
Kd	3.9 nM	PMID18162395	BindingDB

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