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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1B) dopamine receptor
Species	Rattus norvegicus (Rat)
Gene	Drd5
Synonym	DRD1L2 DRD1B dopamine receptor 5 Dopamine D5 receptor D5 receptor D(5) dopamine receptor D(1B) dopamine receptor Gpcr1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	475
Amino acid sequence	MLPPGRNRTAQPARLGLQRQLAQVDAPAGSATPLGPAQVVTAGLLTLLIVWTLLGNVLVCAAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGTFCDIWVAFDIMCSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVGLAWTLSILISFIPVQLNWHRDKAGSQGQEGLLSNGTPWEEGWELEGRTENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSRGAYEPDPSLRASIKKETKVFKTLSMIMGVFVCCWLPFFILNCMVPFCSSGDAEGPKTGFPCVSETTFDIFVWFGWANSSLNPIIYAFNADFRKVFAQLLGCSHFCFRTPVQTVNISNELISYNQDTVFHKEIATAYVHMIPNAVSSGDREVGEEEEEGPFDHMSQISPTTPDGDLAAESVWELDCEEEVSLGKISPLTPNCFDKTA
UniProt	P25115
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2281
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	UNII-YZC2Y51NHJ
Molecular formula	C16H17NO2
IUPAC name	(5R)-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
Molecular weight	255.317
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	2.5
Synonyms	62751-59-1 SK-383933 (R)-1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (R)-SKF-38393 AJ-32307 CTK2B3174 UNII-R7TF327S2C component JUDKOGFHZYMDMF-CQSZACIVSA-N (+)-SKF-38393 CHEBI:125624 SCHEMBL7941051 ZINC1996374 (1R)-2,3,4,5-Tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol (R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium 7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393) CHEMBL24077 SKF 38393 (+) 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393) BDBM50004822 R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (1R)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol CHEBI:131800 SK&F-383933 (5R)-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol (R)-SKF 38393 AC1OAA0J CHEMBL503958 SKF-38393, (R)- 1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-, (1R)- BDBM50274530 R-(+)-Skf 38393 YZC2Y51NHJ (1R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hyrobromide [ Show all ]
Inchi Key	JUDKOGFHZYMDMF-CQSZACIVSA-N
Inchi ID	InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1
PubChem CID	6852376
ChEMBL	CHEMBL24077
IUPHAR	N/A
BindingDB	50004822, 50274530
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	100.0 nM	PMID1831904	BindingDB

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