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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cannabinoid receptor 2
Species	Mus musculus (Mouse)
Gene	Cnr2
Synonym	Peripheral cannabinoid receptor mCB2 CB2-R CB2 receptor CB2 CB-2 cannabinoid receptor 2 (spleen) cannabinoid receptor 2 (macrophage) rCB2 [ Show all ]
Disease	N/A for non-human GPCRs
Length	347
Amino acid sequence	MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
UniProt	P47936
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5373
IUPHAR	57
DrugBank	N/A

Ligand

Name	CHEMBL3290442
Molecular formula	C22H20Cl2N4O2
IUPAC name	1-(2,4-dichlorophenyl)-6-methyl-N-piperidin-1-yl-[1]benzofuro[3,2-c]pyrazole-3-carboxamide
Molecular weight	443.328
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	6.0
Synonyms	SCHEMBL2906511 BDBM50020591
Inchi Key	JMCBVLXQJLOJDU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H20Cl2N4O2/c1-13-5-7-15-18(11-13)30-21-19(22(29)26-27-9-3-2-4-10-27)25-28(20(15)21)17-8-6-14(23)12-16(17)24/h5-8,11-12H,2-4,9-10H2,1H3,(H,26,29)
PubChem CID	59450131
ChEMBL	CHEMBL3290442
IUPHAR	N/A
BindingDB	50020591
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	12.9 nM	PMID24922543	ChEMBL
Ki	13.0 nM	PMID24922543	BindingDB

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