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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Rattus norvegicus (Rat)
Gene	Drd1
Synonym	D1 receptor D1A DADR dopamine D1 receptor Dopamine-1A receptor Gpcr15 [ Show all ]
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
UniProt	P18901
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL265
IUPHAR	214
DrugBank	N/A

Ligand

Name	CHEMBL555619
Molecular formula	C17H20ClNO3
IUPAC name	(1R,3S)-1-(aminomethyl)-6-methoxy-3-phenyl-3,4-dihydro-1H-isochromen-5-ol;hydrochloride
Molecular weight	321.801
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	None
Synonyms	SCHEMBL9802628 [1R,3S] 1-Aminomethyl-3,4-dihydro-5-hydroxy-6-methoxy-3-phenyl-1H-2-benzopyran hydrochloride JFGCJDVUSOHQSC-MOGJOVFKSA-N
Inchi Key	JFGCJDVUSOHQSC-MOGJOVFKSA-N
Inchi ID	InChI=1S/C17H19NO3.ClH/c1-20-14-8-7-12-13(17(14)19)9-15(21-16(12)10-18)11-5-3-2-4-6-11;/h2-8,15-16,19H,9-10,18H2,1H3;1H/t15-,16-;/m0./s1
PubChem CID	45261289
ChEMBL	CHEMBL555619
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
Ki	166.0 nM	PMID1833546	ChEMBL

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