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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
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GPCR

Name	Mu-type opioid receptor
Species	Mus musculus (Mouse)
Gene	Oprm1
Synonym	opioid receptor, mu 1 opioid receptor OP3 Mu receptor MOR-1 MOPr MOP M-OR-1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	398
Amino acid sequence	MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
UniProt	P42866
Protein Data Bank	4dkl, 5c1m, 6dde, 6ddf
GPCR-HGmod model	N/A
3D structure model	This structure is from PDB ID 4dkl.
BioLiP	BL0416752, BL0416751, BL0321492, BL0224753, BL0224754, BL0224755,BL0224756, BL0321491
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2858
IUPHAR	319
DrugBank	N/A

Ligand

Name	Piperidine, 1-[(2E,4E)-1-oxo-2,4-tetradecadienyl]-
Molecular formula	C19H33NO
IUPAC name	(2E,4E)-1-piperidin-1-yltetradeca-2,4-dien-1-one
Molecular weight	291.479
Hydrogen bond acceptor	1
Hydrogen bond donor	0
XlogP	6.3
Synonyms	(2E,4E)-1-(Piperidin-1-yl)tetradeca-2,4-dien-1-one 2,4-Tetradecadien-1-one, 1-(1-piperidinyl)-, (2E,4E)- CHEMBL2442642 (2E,4E)-1-Piperidino-2,4-tetradecadiene-1-one ARLNCELWGQDJPO-QDTXCPDVSA-N Piperidine, 1-(1-oxo-2,4-tetradecadienyl)-, (E,E)- 1-Piperidino-2,4-tetradecadiene-1-one [ Show all ]
Inchi Key	ARLNCELWGQDJPO-QDTXCPDVSA-N
Inchi ID	InChI=1S/C19H33NO/c1-2-3-4-5-6-7-8-9-10-11-13-16-19(21)20-17-14-12-15-18-20/h10-11,13,16H,2-9,12,14-15,17-18H2,1H3/b11-10+,16-13+
PubChem CID	11130083
ChEMBL	CHEMBL2442642
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	5750.0 nM	PMID24095014	ChEMBL

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