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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A2a
Species	Rattus norvegicus (Rat)
Gene	Adora2a
Synonym	A2-AR A2A receptor adenosine receptor A2a RDC8
Disease	N/A for non-human GPCRs
Length	410
Amino acid sequence	MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
UniProt	P30543
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL302
IUPHAR	19
DrugBank	N/A

Ligand

Name	5'-ChloroAdo
Molecular formula	C9H10ClN5O3
IUPAC name	(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-chlorooxolane-3,4-diol
Molecular weight	271.661
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	-0.2
Synonyms	5'-Chloro Adenosine BDBM81788
Inchi Key	AQPIGTYEVNHRPY-SOVPELCUSA-N
Inchi ID	InChI=1S/C9H10ClN5O3/c10-6-4(16)5(17)9(18-6)15-2-14-3-7(11)12-1-13-8(3)15/h1-2,4-6,9,16-17H,(H2,11,12,13)/t4-,5+,6-,9+/m0/s1
PubChem CID	54592325
ChEMBL	N/A
IUPHAR	N/A
BindingDB	81788
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	140.0 nM	PMID1554381	BindingDB

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