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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Somatostatin receptor type 1
Species	Rattus norvegicus (Rat)
Gene	Sstr1
Synonym	SRIF-2 SS-1-R SS1-R SS1R SST1 receptor
Disease	N/A for non-human GPCRs
Length	391
Amino acid sequence	MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCASRISTL
UniProt	P28646
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4652
IUPHAR	355
DrugBank	N/A

Ligand

Name	CHEMBL462157
Molecular formula	C28H31N5O3
IUPAC name	3-[2-carbazol-9-ylethyl(methyl)amino]-1-[4-(4-nitrophenyl)piperazin-1-yl]propan-1-one
Molecular weight	485.588
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.2
Synonyms	N/A
Inchi Key	GRDUAFHKDVPDQM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H31N5O3/c1-29(16-21-32-26-8-4-2-6-24(26)25-7-3-5-9-27(25)32)15-14-28(34)31-19-17-30(18-20-31)22-10-12-23(13-11-22)33(35)36/h2-13H,14-21H2,1H3
PubChem CID	44564784
ChEMBL	CHEMBL462157
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Kd	331.13 nM	PMID19208473	ChEMBL

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