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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Bos taurus (Bovine)
Gene	DRD1
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	Q95136
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2967
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	5-Meo-dpac
Molecular formula	C16H25NO2
IUPAC name	5-methoxy-N,N-dipropyl-3,4-dihydro-2H-chromen-3-amine
Molecular weight	263.381
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.8
Synonyms	BDBM50036862 3-Dipropylamino-5-methyloxychroman CTK8G5655 5-Methoxy-3-(di-n-propylamino)chroman L023817 2H-1-Benzopyran-3-amine, 3,4-dihydro-5-methoxy-N,N-dipropyl- 5-Methoxy-3-(dipropylamino)chroman D0L8NG (5-Methoxy-chroman-3-yl)-dipropyl-amine AC1MIZ4R SCHEMBL2217080 3-(Di-n-propylamino)-5-methoxychroman CHEMBL283606 5-methoxy-3,4-dihydro-N,N-dipropyl-2H-[1]-benzopyran-3-amine 5-methoxy-N,N-dipropyl-3,4-dihydro-2H-chromen-3-amine GOWYIQOIWRLZLO-UHFFFAOYSA-N 110927-00-9 [ Show all ]
Inchi Key	GOWYIQOIWRLZLO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H25NO2/c1-4-9-17(10-5-2)13-11-14-15(18-3)7-6-8-16(14)19-12-13/h6-8,13H,4-5,9-12H2,1-3H3
PubChem CID	3082597
ChEMBL	CHEMBL283606
IUPHAR	N/A
BindingDB	50036862
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<1000000.0 nM	PMID7912735	BindingDB,ChEMBL
IC50	100000.0 nM	PMID8863806, PMID7912735	BindingDB,ChEMBL

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