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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Glucose-dependent insulinotropic receptor
Species	Mus musculus (Mouse)
Gene	Gpr119
Synonym	G protein-coupled receptor 119 G-protein coupled receptor 119 G-protein coupled receptor 2 glucose-dependent insulinotropic receptor GPCR2 GPR119 [ Show all ]
Disease	N/A for non-human GPCRs
Length	335
Amino acid sequence	MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISGLVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGLVAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLLFVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSPFLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKFFTSILLLLPARNRGPERTRESAYHIVTISHPELDG
UniProt	Q7TQP3
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5263
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL1771095
Molecular formula	C21H27N7
IUPAC name	2-methyl-6-[4-[1-(5-methylpyrazin-2-yl)piperidin-4-yl]piperidin-1-yl]pyrimidine-4-carbonitrile
Molecular weight	377.496
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.0
Synonyms	BDBM50342694 SCHEMBL3619230 2-methyl-6-(1''-(5-methylpyrazin-2-yl)-4,4''-bipiperidin-1-yl)pyrimidine-4-carbonitrile
Inchi Key	GOVGOKPXNWGDER-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H27N7/c1-15-13-24-21(14-23-15)28-9-5-18(6-10-28)17-3-7-27(8-4-17)20-11-19(12-22)25-16(2)26-20/h11,13-14,17-18H,3-10H2,1-2H3
PubChem CID	54583895
ChEMBL	CHEMBL1771095
IUPHAR	N/A
BindingDB	50342694
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	82.0 nM	PMID21273063	BindingDB,ChEMBL

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