>PF15273 (658 residues) QRSETRDSSCQTEEVKVVPPSMRRIRAQKGQGIAAQMGHFSGSSGNMSVLSDSAGIVFPS RLNSDAGFHSLPRSGARANIQSLEPRLGPLGPAGDMDGTFPYQRGHPQADENSGHLGGAS RTGTLMRPKSQELRHFESENVTSPACVVSPHAGYSTSIIPNAKLSSSSEVIAIHTAQSAG QLESRSSSSLHAKIKSRDHLISRHAVRDDHQSPSRHWNEGHTTMLSQALDPQSSGAPTLL SLCDSAVSLNAPANRENGSQAMPYNCRNNLAFPAHPQDVDGKSESSYSGGGGHSSLEPWE YKASGNGRASPLKPHLATPGYSTPTSNMSSCSLDQTSNKEDAGSLYSEDHDGYCTSLHAD SGHGSGNLCNSSDGFGNPRHSVVNVFDGRAQKNQGDRSNYQDKSLSRSISLKKAKKPPLP PSRTDSLRRIPKKSSQSNGQVLSESLIATLQHSLQLSLPGKGGSSPSQSPCSDLEEPWLP RSRSQSTVSAGSSMTSATTPNVYSLCGVTPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPG NPAGGCSASNGAPTGNGPVRHVQEGSRATMPQVPSASVKPKIMSPEKSHRVISPSSGYSS QSNTPTALTPVPLFLKSMSPANGKGKPKPKVPERKSSLISSISTSSSSTSLSSNTSNE |
Rank | PDB hit | ID1 | ID2 | Cov | Norm. Zscore | Threadingprogram | 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |||||||||||||
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Seq | QRSETRDSSCQTEEVKVVPPSMRRIRAQKGQGIAAQMGHFSGSSGNMSVLSDSAGIVFPSRLNSDAGFHSLPRSGARANIQSLEPRLGPLGPAGDMDGTFPYQRGHPQADENSGHLGGASRTGTLMRPKSQELRHFESENVTSPACVVSPHAGYSTSIIPNAKLSSSSEVIAIHTAQSAGQLESRSSSSLHAKIKSRDHLISRHAVRDDHQSPSRHWNEGHTTMLSQALDPQSSGAPTLLSLCDSAVSLNAPANRENGSQAMPYNCRNNLAFPAHPQDVDGKSESSYSGGGGHSSLEPWEYKASGNGRASPLKPHLATPGYSTPTSNMSSCSLDQTSNKEDAGSLYSEDHDGYCTSLHADSGHGSGNLCNSSDGFGNPRHSVVNVFDGRAQKNQGDRSNYQDKSLSRSISLKKAKKPPLPPSRTDSLRRIPKKSSQSNGQVLSESLIATLQHSLQLSLPGKGGSSPSQSPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGVTPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSASNGAPTGNGPVRHVQEGSRATMPQVPSASVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPLFLKSMSPANGKGKPKPKVPERKSSLISSISTSSSSTSLSSNTSNE | |||||||||||||||||||
1 | 2pffB | 0.17 | 0.05 | 0.29 | 1.08 | MRFsearch | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------VRVIVAGTL--------------------------------------------------------------------------------------DINPDDDYGFKQGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-------------------------------------GGGGGGGGGGGGGGGGGGGGGGG--------------------------------------------------------------------------GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-------------------------------------GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG--------------------------------------GGGGGGGGGG------------------------------- | |||||||||||||
2 | 5julA | 0.08 | 0.07 | 0.90 | 1.47 | SPARKS-K | IALMAEDEAIFEEAHKQVQRFDDRVWFTNHGRFHQHRQIINLGDNRHAVYLHNDFCLIALASGQ-------------ILLTDVSLEGEDTYLLRDESDSSDILRMAVFNQQKHLITLHCNGSVKLWSLWPSVVKRFIGSYANLKIVAFYLNEDAGLIQLHVAFINGDVSILNWDEQDQEFKLSHVPVL------KTMQSGIRCFVQVLKRYYVVCTWDLTSSNTLELHVFNVENDTPLALDVFDERSKTATVLLIFKYSVWRLNFLPGLSVSLQSEAVGSFITCGKRSTDGRYGTSEGYDLKISDPV---------LRSNVSEHIECVDIYELFDPVYKYIVL--CGAKGKQVVHVHTLGSNSHQNREIAWVHSADEISVMTKACEPNVYLRSLMDMTRERTQLLAVD------------SKERIHLIKPAWSTITPTHAASDEQIFVGYVDGVIIDVIHDTALPQQFIEEPIDYLKQVSPAHSAQLEKIDPLQPNDQWPLMMDVSTKYASLQEGQYI--------ILFSD---------HGVCHLDIANPSAFVKP------KDSEEYIVGFDLKNSLLFLAYENNIIDVFRLIFSCCEEEIAQKAKISYLVATGTMGFENGENRKVQLIYSVHEHCIRQLLFSPCKLLLISCAEQL | |||||||||||||
3 | 3chnS | 0.09 | 0.07 | 0.84 | 1.31 | MUSTER | ----------------------------------------------------------------------------KSPIFGPEEVNSVEGNS-YYPPTSVNRHTRKYRQGARGGCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGLGINSRGLSFDVS---EVSQGPGL-LNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFNQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGSSVAVLPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDA-WCLTNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLK------PCHFPCKFSSYEKYWCKNTGCQALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEGW-------GVKQGHFYGETAAVYAVEERKAAGSRDVSLAKADAAPDEKV------LDSGFREIENKAIQDPR---- | |||||||||||||
4 | 2ht5A | 0.08 | 0.04 | 0.55 | 0.72 | DisCoVER | NNTEAICD--AKGFAPFSKDNGIRIG-SRGHIFV-IR----------EPF------VSCSPI------ECRT---FFLTQ--------------------------GSLLNDKHSNGTVK---DRSPFRT-LM-----------SVEVGQS--PNVYQARFEAV----AWSATACHDGK------------------KWMTVGVTGPDSKAVAVIHYGGVPTDVVNSWAGDI-------LRTQESSCTCICYWVMTDGPAAQYRIYKANQGRIIGQTDIGHIEECSCYPNDGKVEC-VC-R--------------------DGWT--G-------------T-NRPVLVISPYRVGYLCAGIPSDTPRGEDFTGS-----CTSPMGNQ----------------G-YGVKG-----------FGFR-------------QGTDV--W------------------MG-RTI--SRTSRSGFEILRIKNGW-TQTSKEQIRKQVVVDNLNW------S--GYSGSFT-LPVEL-------------------------------------------------SGKDCLVPCFWVEMIRGKTIWTSSS--SIVMCGVDYEVA-----------------DWSWHD------GAILPFD-- | |||||||||||||
5 | 2ecfA | 0.09 | 0.08 | 0.93 | 0.80 | CEthreader | ---------KLTLEAITGPLPLSGPTLMKGSRVTFLRGKDSDRNQLDLWSYDIGSGQTRLLVDSKVVLAMTGIVDYQWSQRLLFPLGGELYLYDLKQEGKAAVRQLTHGEGFATDAKLSPKGGFVSFIRGRNLWVIDLASGRQMQLTADGSTTIGNGI-----------------AEFVADEEMDRHTGYWWAPDDSAIAYARIDESPVPVQKRYEVYADRTDVIEQ------------------RYPAAGDANVQVKLGVISPAEQAQTQWIDLGKEQDIYLARVNWRDPQHLSFQRQSRDQKKLDLVEVTLASNQQRVLAHETSPTWVPLHNSLRFLDDGSILWSSERTGFQHLYRIDSKGKAAALTHGNWSVDELLAVDEKAGLAYFRAGIESARESQIYAVPLQGGQPQRLSKAPGMHSASFARNASVYVDSWSNNSTPPQIELFRANGEKIATLVENDLADPKHPYARYREAQRPVEFGTLTAADGKTPLNYSVIKPAGFDPAKRYASQTVTDSWPGRGDHLFNQYLAQQGYVVFSLDNRGTPRRGRDFGGALYGKQGTVEVADQLRGVAWLKQQPWVDPARIGVQGWSNGGYMTLMLLAKASDSYACGVAGAPVTDWGLYDSHY-TERYMDLPARNDAGYREARVLTHIEGL | |||||||||||||
6 | 6tnfA | 0.06 | 0.06 | 1.00 | 0.87 | EigenThreader | GVFEELLRTSGIILKVGEGQNE---IAVDQTAFQKKLRVALEKHPSIKDRSQFKNCLLPCTPARCESLIKLLLGRLIVNQFKWLDQHDIITSLPEILEDSQLLKQGRRLTVPILDALSRLDLDAELLAKVRQSAMTIVPSVKLEDLPVVIKFILHNVKAADSLDLSSTSLAVRFQKDVSEAWIKAIENSTSLLLIHSTNSKNRKQTEKVLRSKIRLGCMPEQLMQNAFQNHSMVIKDFFPSILSLAQTFLHSAHAFAVFDSYCQQEVVCALVTHVCSGNETELDISLDVLTDLVILHPSLLLRYATFVKTILDSMQKLNPCQIRKLFYILSTLAFSQRQERKWLSSSVPNHKQMGIIGAVTMMGSVALIEGNLDLQLLDKFGKSLVEDFPNDFVVDLSPTVDGSFLFPVKSLYNLDEDGAIAINLLPLVSQKRVVSPICLSPCFRLLRLYTGEQNNGSLEEIDALLGCPLYLTDLEVEGKLDSLSKQEREFLCQQDAEMKGKCLAATPGYVPPPAQLQSYRPYFRELDHCGLLTLGPAELCFLLDDMCWKLEHVLTFSHLCQRSPKEVAVCVVKLLKPLCNHMENMHNYFQTVIPNESGLNIQEYQLMSSCYHQLLLAFRLLFAWSGFSQHENSNLLRSALQVLADRLKPGETEFLPL | |||||||||||||
7 | 2q2eB | 0.13 | 0.08 | 0.64 | 0.44 | HHpred | ----IEDNGPGIVRIKLLYG-FHALK-SRGQGIGISAAVLYATAGHTKILSKTAPAHYYETNEPDILRDWFRPHGTQIELEMRAAYVKRQSIYEYLKATNPHARITLIDPNEEVFERAPA-EEILPHPEGIELGTLMK--MLH--------Y--TEPFLRYCKLLTAEEI-----CKAAGL-D------PEIDPHA---LG-RHEARKLIEA-------------FEKVKIMAPPTDCLSPIGEDL--IYRGLEKETTVDFIATSTRKPAVYSGNP----------FVVEVGMAYGGNL--PKEEKIRFANRVPLYQQGGCVTTH-AV-----------------EDIKWKQY--------GLNQ-----PGGGIPGPVILLIHVFTSESKDAIADIPVIVARKLKHYLSKQSNLKKR--REKEIIITKVPAKVAHVLEKDVP--DINPVVAKIMGNLLVH------------RVIKNNGDGTVDVAIKVKN----AYSFRVHEMLPCKVKPPKVVTMGNDYDYVWDI--SASAGS-------------------------------------------------------------------------------------------------------------------------- | |||||||||||||
8 | 6em5m | 0.23 | 0.05 | 0.20 | 0.42 | MRFsearch | ----------------------SKIQRNE----------------------------------------------------QTDDSINPYEPLIDWFT----------RHEEVMPLTAVPEPKRRFVPSKNEAKR----------------------------------VMKIV-----------------------------------------------------------------------------------------------------------------------YQYDLWGDSTETN---------------------------------------------------------------------------------------------------DHVMHLRAPKLPPPTPQKYSALRKVPG---------YGESIRERFERSLDLYL-------------------------------------------------------------------------------------------------------------------DPNSLIPELPSPKDLR--------------------------------------------------------------------- | |||||||||||||
9 | 3cnfB | 0.09 | 0.08 | 0.97 | 0.83 | FFAS-3D | LTETRLDYALNIDHFSVLNINLRALMEANVDDRIKALQAHSMISTQFHGPNQDHDHIIRCLMLAAANYPRLEGSANVIRPVSEKRYFPENLEQNQSAARLVSAVKARASEADISSIHLAIAREVSPMFNVHELKKIAESFEDPSSIVVVLEFILFALFFPTEFNRIQNVLLLFFSRWYPVEYGIFVQRGATYTINAAGEFEFSGRNEKWDQALYLSEDVPLAGANTIIAIMRLFTPQGFLRTDDLAIAANFPRASRNPQTYIPYTNQRGTVVYATMSNFMLNFTNNFATHVAVVLYQSGVINGPASTYLRENEVLVVMPDYYDVVSRFANANLQMNNNRYHESVLEIAQLRALMPTLSTSQIRHAIERIAQITDVDSTDYGKLTLRFLGTLTRSLKMQNAQIRRIRPDLRYDDQIDIEAFRWSRYFLDELQLRRLSVGLRLITNPRIARRFNGVRIMYLTDDDPDPDFVPDVQYAHRLSSLANKRNRVTYTHPPTGMAYPSPTGRPHVHMTINERAGMSKLVADNIIASVIKSNWVVDILDIEYTAEVMSEGYTQHVDAESIMTAPKGKLFHLQFMDGLLRPE-----------ASGEDMRLIYPLQPISVARSMRAIVNHN-------EVD-RPREMDTGTLSRNGDLLYSPVANGQ | |||||||||||||
10 | 5jcss | 0.10 | 0.09 | 0.94 | 1.37 | SPARKS-K | SLRQLGRKIQNSTPIMLIGKA--------GSGLINELSKYMGCHDSIVKLGEQTGTYTSGDKPGTFEWRVLAKEGRWVLIEDID-----KAPTDVLSILLSRELTIPSRGETVKAANGFQLISTVRINEDHQKDSSNK-IYNLNMIGMRIWNVIELEEPSEEDL-----------THILAQKFPILTNLIPKLIDSYKNVKSIYMNTKFISLNKGAHTRVVSERLDILFKNNGINKPDQLIQSSVYDSIGAIGEFKALEPSLDIASSRISLFLTQHVPTLENLDDSIKIGRKEKLNIQKKSMNSTLFAFTNHSLRSVCIQMTEPVAKMLAKKLTNVSQQTETG-----DLLG---------GYKPKTFETLFNATFSLKKNEKFHKMLHRCFNKNQWKNVVKLWNEAYKMAQSILKITNTENENENAKKKRLNTHEKKLLLDKWADFNDSVKKFEAQSSSIENSFVFNFVETIRAGEWLLTEPDSRSILKGDAEPIKAHPDFRIFACMNPAKRDLPMIRSRFTE---IYVHSPERDITDLLSIIKYSVSDEWVGNDIAELYLEAKKLSDNNTIVDGSNQKPHFSIRTLTRTLLYVTDIIHIYGLRRSLYFCMSFLTLLDQKSEAILKRLKNVKSIMSYIITPFVEKNMMNLVRATSGK | |||||||||||||
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References: | |
1. | Wei Zheng, Yang Li, Chengxin Zhang, Robin Pearce, S. M. Mortuza, Yang Zhang. "Deep-learning contact-map guided protein structure prediction in CASP13." Proteins: Structure, Function, and Bioinformatics, 87: 1149-1164 (2019). |