>PF10221 (687 residues) SVSHKTVFVVDHCPYMAESSRQQIECDVLTKSRSQGVIPLAPVSKSLWTCAVECSMEYCR ILYDIYPSKKLVNYIVSDSEFHILNSWRQEDQSVQELMAALAAVGPPNPREDPECCSILH GLVAAVESLCKITEYQHESRTSLMDMAERVANRGRIICLTNAKSDTHVRMLEDCVLETIQ EQNKLAAGSDRLMPIQQCELVLVHIFPQGDDTLVSDRPKKEISSVLSSEVHSVRAGRHLA SKLNVLVQQHFDLASTTITNIPMKEEQHANTSANYDVELLHHRDAHMEFIKSGDLHMVGT TSRDSGLKETVTLKWCTPRTNSVELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLE QPRKSGSKVISHMLSCHGGEIFLHVLNSTRSTLEDPPSISEGCGGRVTDYRITDFGEFMR ENRLTPFPDMPVDAAGRLPFERAKAQLERHTRYWPMIISQTTIFNMQAVVPLANLIVKDS LTEDDVLTCQKTVYNLVDMERKNDPLPISTVGSRGKGPKRDEQYRIMWNELETLVKTHVG TSERHQQVLECISACRSKPPEEEERKKRGRKREDKEDKTEKNGKESEEKTWTQDSERPKG LTEREKDDQSESEVIKDSPDSPEPFNKKPRLASEEIVSIEKSKGPVSLLSLWTSRITQAN SRKHQEFAGRISSVNNKAELYQHLKDE |
Rank | PDB hit | ID1 | ID2 | Cov | Norm. Zscore | Threadingprogram | 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 660 680 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |||||||||||||
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Seq | SVSHKTVFVVDHCPYMAESSRQQIECDVLTKSRSQGVIPLAPVSKSLWTCAVECSMEYCRILYDIYPSKKLVNYIVSDSEFHILNSWRQEDQSVQELMAALAAVGPPNPREDPECCSILHGLVAAVESLCKITEYQHESRTSLMDMAERVANRGRIICLTNAKSDTHVRMLEDCVLETIQEQNKLAAGSDRLMPIQQCELVLVHIFPQGDDTLVSDRPKKEISSVLSSEVHSVRAGRHLASKLNVLVQQHFDLASTTITNIPMKEEQHANTSANYDVELLHHRDAHMEFIKSGDLHMVGTTSRDSGLKETVTLKWCTPRTNSVELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQPRKSGSKVISHMLSCHGGEIFLHVLNSTRSTLEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFPDMPVDAAGRLPFERAKAQLERHTRYWPMIISQTTIFNMQAVVPLANLIVKDSLTEDDVLTCQKTVYNLVDMERKNDPLPISTVGSRGKGPKRDEQYRIMWNELETLVKTHVGTSERHQQVLECISACRSKPPEEEERKKRGRKREDKEDKTEKNGKESEEKTWTQDSERPKGLTEREKDDQSESEVIKDSPDSPEPFNKKPRLASEEIVSIEKSKGPVSLLSLWTSRITQANSRKHQEFAGRISSVNNKAELYQHLKDE | |||||||||||||||||||
1 | 5kf6A | 0.07 | 0.04 | 0.59 | 0.67 | DEthreader | -----------------------RRPET-CL--------------------------------L---------------EALL-----------TWGLVVTGKLTSTV-----------G--FVTGETIREALKRSKELEEKG------F-SYSYDMLGEAATTAADAERYYRDYESAIHAIGK-ASA-GR-IYEGPGISIKLSARYSRAQARVMELPVKALLNYIGLNIDAEEADRLELSLFVVQALIMVRLVKGAYWDA-----------RKIHTDSYIACAAKLL------------------------HNAQ--------------HMAFCGEPLLNGASVHRINDVSIDELIADP----------V----------EVVRAMPVVGAKH-D-----------RIALPAELFRTNSAGLDL-LLTLANPGDAGKSALNAIAEVR-------------L--QVVGDVITSAFDSAGQRCSA------------------------------------------AGNLYINIIGAFGGRGL-SGTGPKAGGPLYLGAPVPPQHSS----------T-D-PVLLDFAKWL----ARAEAEAARNAGSS--LGLDLHARGRI-------------YHQLAAALATGNS-GPFAGA-NK-IAALPGPLLLVQAAAYCLNWLVEE---- | |||||||||||||
2 | 6sn1A | 0.70 | 0.36 | 0.51 | 0.67 | DEthreader | KIFSKTVFVVDHCPYMAESCRQHVEFDM-------LIIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILHGLVAAVETLCKITEYQHEARTLLMNAER-VGNRGRIICITNAKSDSHVRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRSKKELSPVLTSEVHSVRAGRHLATKLNILVQQHFDLASTTITNIP---------M-YDVELLHHK-DAHVDFL-----------------ETITLKWCT-PRTNNIELHYCTGAYRISP-VDVNSRSSCLTNFLLN-GRSV-LLEQP-SKVISHMLSSHG-GEIFLHVLSSSR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | |||||||||||||
3 | 6sn1A | 0.83 | 0.62 | 0.74 | 27.12 | HHpred | SESHKTVFVVDHCPYMAESCRQHVEFDML-------IIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILHGLVAAVETLCKITEYQHEART--LLMAERVGNRGRIICITNAKSDSHVRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRSKKELSPVLTSEVHSVRAGRHLATKLNILVQQHFDLASTTITNIPM-----------YDVELLHHKDAHVDFL------------------ETITLKWCTPRTNNIELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQP----SKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLDPRYDGSLEVPLERAKDQLEKHTRYWPMIISQTTIFNMQAVVPLASVIVKESLTEEDVLNCQKTIYNLVDMERKNDPLPIS--------PKRDEQYRIMWNELETLVRAHINNSEKHQRVLECLMACRSKP-------------------------------------------------------------------------------------------------------------------------------- | |||||||||||||
4 | 3k4xA | 0.10 | 0.10 | 0.94 | 0.55 | MUSTER | KEDGIIAQAVD-------DSRVLLVSLEIGVEAFQEYRCDHPVTLGM---DLTSLSKILRC----GNNTDTLTLIADNTPDSIILLFDTKKDRIAEYSLKLMDIDADFLKIEELQYDSSSEFSKIVRDLSQLSDS---INIMITKETIKFVADGSVIIFVDMEHPETSIKLEMDLTFGAKYLLDIIKGSSLS---DRVGIRLSSEAPALFQFDLKSGFLQ-LAPKLEAKFEEASLFKRIIDGFKDCVLVNFQAQAVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTP-DSIILLFEDTKKDRIELQY-DSTLSL-PSSEFSKIVRDLSQL---SDSINIMITKE----TIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQ----DLKSFLQFFPKFNLEAKFEEASLFKRIIDGFK--DCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSSEFSKIVRDLSQLSDSINIMITKETIKGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQF-DLKSG | |||||||||||||
5 | 6sn1A | 0.83 | 0.61 | 0.74 | 1.40 | MRFsearch | --SHKTVFVVDHCPYMAESCRQHVEFDML-------IIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILHGLVAAVETLCKITEYQHEARTLLMN-AERVGNRGRIICITNAKSDSHVRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRSKKELSPVLTSEVHSVRAGRHLATKLNILVQQHFDLASTTITNIP-----------MYDVELLHHKDAHVDF------------------LETITLKWCTPRTNNIELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQPS----KVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLDPRYKISLEVPLERAKDQLEKHTRYWPMIISQTTIFNMQAVVPLASVIVKESLTEEDVLNCQKTIYNLVDMERKNDPLPIS--------PKRDEQYRIMWNELETLVRAHINNSEKHQRVLECLMACRSKP-------------------------------------------------------------------------------------------------------------------------------- | |||||||||||||
6 | 2pffB | 0.06 | 0.05 | 0.91 | 1.11 | MAPalign | -AQLVAIFGGQGYFEELRDLKFSAETLSELIRTTLDAEILCPLIGVIQLAHYVVTAKLLFTPGELRSYLKGATGHSQG---LVTAVAIAETSFFVSVRKAITVLEISLVNGAKNLVVSQSLYGLNLTLRHLLVPASDLINKDLVISERIVATHILDFGPGG----------ASGLGVLTHRNK---------DGTGVRVIVGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG------GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGQKAAQDVWNRADNHFKEINEHSTYTFRSEKGLLSAQFTQPALTLMEKAAFEDLKSTFAGHSLGEYAALASLSLVEVVFYRGMTMQVGRSNYGMIAINPGRVAASFSQEALQYVVERVGKRTGWLVEIVNYNVENQ----------------------------QYVAAGDLRALDTGGGGGGGGGGGGGGGGGGGGGGGGGGG-- | |||||||||||||
7 | 6sn1A | 0.82 | 0.61 | 0.74 | 3.15 | SPARKS-K | SESHKTVFVVDHCPYMAESCRQHVEFD-------MLIIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILHGLVAAVETLCKITEYQHEARTLLMNAE-RVGNRGRIICITNAKSDSHVRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRSKKELSPVLTSEVHSVRAGRHLATKLNILVQQHFDLASTTITNIPM-----------YDVELLHHKDAHV-------------DFLET-----ITLKWCTPRTNNIELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQP----SKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLDPRYKIDLEVPLERAKDQLEKHTRYWPMIISQTTIFNMQAVVPLASVIVKESLTEEDVLNCQKTIYNLVDMERKNDPLPIS--------PKRDEQYRIMWNELETLVRAHINNSEKHQRVLECLMACRSKP-------------------------------------------------------------------------------------------------------------------------------- | |||||||||||||
8 | 6sn1A | 0.76 | 0.56 | 0.74 | 1.82 | MAPalign | IFSEKTVFVVDHCPYMAESC--RQHVEF---DMLIIPLAPISK--SLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILHGLVAAVETLCKITEYQHEARTLLMNAE-RVGNRGRIICITNAKSDSHVRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRSKKELSPVLTSEVHSVRAGRHLATKLNILVQQHFDLASTTITNIPMY-----------DVELLHHKDAH------------------VDFLETITLKWCTPRTNNIELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQP----SKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLDPRYKIDGSLEPLERAKDQLEKHTRYWPMIISQTIFNMQAVVPLASVIVKESLTEEDVLNCQKTIYNLVDMERKNDPLP--------ISPKRDEQYRIMWNELETLVRAHINNSEKHQRVLECLMACR----------------------------------------------------------------------------------------------------------------------------------- | |||||||||||||
9 | 6sn1A | 0.83 | 0.62 | 0.74 | 1.44 | CEthreader | SESHKTVFVVDHCPYMAESCRQHVEFDML-------IIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILHGLVAAVETLCKITEYQHEARTLLM-NAERVGNRGRIICITNAKSDSHVRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRSKKELSPVLTSEVHSVRAGRHLATKLNILVQQHFDLASTTITNIPM-----------YDVELLHHKDAHVDFL------------------ETITLKWCTPRTNNIELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQP----SKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLDPRYKGSLEVPLERAKDQLEKHTRYWPMIISQTTIFNMQAVVPLASVIVKESLTEEDVLNCQKTIYNLVDMERKNDPLPIS--------PKRDEQYRIMWNELETLVRAHINNSEKHQRVLECLMACRSKP-------------------------------------------------------------------------------------------------------------------------------- | |||||||||||||
10 | 6sn1A | 0.83 | 0.61 | 0.74 | 10.47 | HHsearch | SESHKTVFVVDHCPYMAESCRQHVEFDML-------IIPLAPISKSLWTCSVESSMEYCRIMYDIFPFKKLVNFIVSDSGAHVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILHGLVAAVETLCKITEYQHEARTL-LMNAERVGNRGRIICITNAKSDSHVRMLEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGEDSLVSDRSKKELSPVLTSEVHSVRAGRHLATKLNILVQQHFDLASTTITNIPM-----------YDVELLHHKDAHVDFL------------------ETITLKWCTPRTNNIELHYCTGAYRISPVDVNSRPSSCLTNFLLNGRSVLLEQP----SKVISHMLSSHGGEIFLHVLSSSRSILEDPPSISEGCGGRVTDYRITDFGEFMRENRLTPFLDPRYKGSLEVPLERAKDQLEKHTRYWPMIISQTTIFNMQAVVPLASVIVKESLTEEDVLNCQKTIYNLVDMERKNDPLPIS--------PKRDEQYRIMWNELETLVRAHINNSEKHQRVLECLMACRSKP-------------------------------------------------------------------------------------------------------------------------------- | |||||||||||||
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References: | |
1. | Wei Zheng, Yang Li, Chengxin Zhang, Robin Pearce, S. M. Mortuza, Yang Zhang. "Deep-learning contact-map guided protein structure prediction in CASP13." Proteins: Structure, Function, and Bioinformatics, 87: 1149-1164 (2019). |