>PF06874 (640 residues) KYLKLLSEQFPTIASACTEIINLQAILNLPKGTEHFLTDIHGEYEAFTHVLRNASGVIKR KIDDMFGTSLRESEKKSLATLIYYPEQKLQIIKTQEKDINDWYKITLYQLIEVCRNVSSK YTRSKVRKALPKDFAYIIEELLHEQENKSNKQNYYNQIIKTIIDIDRGSEFIIALAKLIQ RLSVDRLHILGDIYDRGPGAHIILDELINHHSVDIQWGNHDILWMGAAAGSETCIANVIR ISTRYANLKTIEEGYGINMLPLATFALEFYKDDNCIPFKPKVPSQADYREKDIQLITKMH KAISIIQLKLEGQLIKRRPEFNMNDRLLLDKIDYEKGVINLYGKTYKLNDTLFPTIDPKD PYKLIEEEQELISQLKNSFTNSEKLQKHIRFLYSKGSMYLKFNSNLLYHGCITMNEDGSF RKVTINGKKYYGKSLLDRLDRLAREAYFGKKNSADQQYGLDMMWYMWCGEHSPLFGKDKM TTFERYFINDKETHVEIKNPYFKLRDNEKACCNVLKEFGLNPKTSHIINGHVPVKTKDGE SPIKANGKLLVIDGGFSKAYQPQTGIAGYTLIYNSYGLLLASHEPFESIQKAIEEEKDIL STTTVLEKTSKRKCVSDTDIGIELEQQIGDLKMLLTAYRK |
Rank | PDB hit | ID1 | ID2 | Cov | Norm. Zscore | Threadingprogram | 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |||||||||||||
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Seq | KYLKLLSEQFPTIASACTEIINLQAILNLPKGTEHFLTDIHGEYEAFTHVLRNASGVIKRKIDDMFGTSLRESEKKSLATLIYYPEQKLQIIKTQEKDINDWYKITLYQLIEVCRNVSSKYTRSKVRKALPKDFAYIIEELLHEQENKSNKQNYYNQIIKTIIDIDRGSEFIIALAKLIQRLSVDRLHILGDIYDRGPGAHIILDELINHHSVDIQWGNHDILWMGAAAGSETCIANVIRISTRYANLKTIEEGYGINMLPLATFALEFYKDDNCIPFKPKVPSQADYREKDIQLITKMHKAISIIQLKLEGQLIKRRPEFNMNDRLLLDKIDYEKGVINLYGKTYKLNDTLFPTIDPKDPYKLIEEEQELISQLKNSFTNSEKLQKHIRFLYSKGSMYLKFNSNLLYHGCITMNEDGSFRKVTINGKKYYGKSLLDRLDRLAREAYFGKKNSADQQYGLDMMWYMWCGEHSPLFGKDKMTTFERYFINDKETHVEIKNPYFKLRDNEKACCNVLKEFGLNPKTSHIINGHVPVKTKDGESPIKANGKLLVIDGGFSKAYQPQTGIAGYTLIYNSYGLLLASHEPFESIQKAIEEEKDILSTTTVLEKTSKRKCVSDTDIGIELEQQIGDLKMLLTAYRK | |||||||||||||||||||
1 | 2z72A | 0.22 | 0.09 | 0.41 | 1.91 | HHpred | ---------------------LSSEIKQIMIKKVVALSDVHGQYDVLLTLLKKQ-KIIDS--------------------------------------DGNW------------------------------------------------------------------------------AFGEGHMVMTGDIFDRGHQVNEVLWFMYQLDMVHLLMGNHEQMVLGGD--------------LRY-------------------------VH-------QRY----------DIATTLI----------------------NR---------------------PY-----------------------------NKLYSADTEI---GQWLRSKNTI-IKINDVLYMHGGISSEWIS-------RE------LTLDKANALYRANVDASKK---SLKADDLLNFLF-FGNGPTWYRG-------YFS-ET--------------FTEAELDTILQHFNVN----HIVVGHTSQE----RVLGLFHNKVIAVDSSIKV------GKSGELLLLENNRLIRGLYDG------------------------------------------------------- | |||||||||||||
2 | 3m1iC | 0.09 | 0.08 | 0.85 | 1.05 | CNFpred | QDDEVFKTQKNLINKSDLTLVQILKQEWPQ-NWPEFIPELIGSSVNVCENNMIVLKLLSEEVFDFSAEQMTQAKALHLKNSMSKFEQIFKLCFQVLGSSSSLIVATLESLLRYLHWI----PYRYIYE--TNILELLSTKFMTSP----DTRAITLKCLTEVSNLK-NDLIKRQTVLFFQNTL-----------------QQIATSVMP-VTADL-----KATYANANGNDQSFLQDLAMFLTTYLNRALLESDERELLLNAHQYLIQLSKI------------------EERELFKTTLDYWHNLVADL-EEICSQL------RLVIIENMVRPEEVLVVENEIVRE------FVKESDTIQLYKSEREVLVYLTHLNDTEEIMISKLARQIDSEWSWHNINTLSWAIGSISG----TMSED-------TEKRFVVTVIKDLLDLTVK--KRGKDNKAVVASDIMYVVGQYPRFLKAHWNFLRTVILKLFEFMHE-THEGVQDM-ACDTFIKIVQKCKY----------HFVIQQPRESEPFI-----QTII-RDIQKTTADLQPQQVHTFYKACGIIISEERSVAERNRLLSDLLPNMAWDTIVEQSTNPTLLLDSETVKIIANIIKTNVAVCTSMGA | |||||||||||||
3 | 2z72A2 | 0.19 | 0.08 | 0.41 | 0.59 | DisCoVER | -IMPDT---------------------YLGIKKVVALSDVHGQYDVLLTL--LKK--------------------------QKIIDS----------------------------------------------------------------------------------------DGNWA-FGEGHMVMTGDIFDRGHQVNEVLQLDQQAGMVHLLMGNHE---QMVLGG-------DLR----Y-V--HQ--RYDTT-------------------------------------------------------------------------------------------------------------------LINRPYNKL-YSADIGQWLR-SKNTIIKINDVLYMHGGISS---EWI---SR-------ELTLDKANALYRANVD----------ASKLLNFLFFG-NGPTWY----------------------RGYFSETFTEAELDTILQHFNV----NHIVVGHTSQ----ERVLGLFHNKVIAVDSSIKG------KSGELLLLENN-RLIRGLY---------------D-GTRETLQ-E--NSLN------------------------- | |||||||||||||
4 | 5jpeA | 0.12 | 0.06 | 0.48 | 0.61 | CEthreader | ------------------------------------------------------------------------------------------------------HMIDIDSLIDKLLNAGFSGKRTKNVCLKNTEIELICASAREIFLSQPSL-LELAPPVKVVGDVHGQYHDLIRIFSKCGFPPKTNYLFLGDYVNRGKQSLETILLLLCYKIFFLLRGNHECANVTRV----------------YGFYDECKRRCN-----------------------------------------------------------------------------------------------------------------------------IKTWKLFIDTFNTLPIAAIVAGKIFCVHGGLSPVLNSMDEIRNIARPTDVPD---------------------------------FGLLNDLLWSDPA----------DTINEWEDNERGVSYVFSKVAINKFLSKFNFD----LVCRAHMVVE----DGYEFFNDRTLVTVFSAPNYCGEFDNWGAVMGVSEDLLCSFELLDPLDSAALKQVMKKEKQ---------------------------------------- | |||||||||||||
5 | 2z72A2 | 0.13 | 0.05 | 0.40 | 0.78 | EigenThreader | ----------------------------SSGIKKVVALSDVH---------------------------------------------------------------------------------------------------------------------------GQYDVLLTLLKKQK--IIEGHMVMTGDINEVLWFMYQLDQQARDAGGMVHLLMGNHEQMVLGGDLRY--------------------------------------------------------------------------------------VHQRYDIATTLI-------------------------NRPYNKLYSAD---------------TEIGQWLRS-----KNTIIKINDVLYMHGGISSEWISRE-----------LT-----LDKANALYRANVDASKKSLKADDLLNFLFFGNGPTWYRG------------------YFSET-----FTEAELDTILQHFNV----NHIVVGHTSQE----RVLGLFHNKVIAVDSSIKV-----GKSGELLLLEN--NRLIRGLYD--------------GTRETLQENQ------------------------------- | |||||||||||||
6 | 4ltyC | 0.17 | 0.08 | 0.45 | 0.70 | HHpred | --------------------------------------------------------------------------------------------------------------------------------------------ILHTSDWSKSR-------------EAEHQAFLDWLLETAQTHQVDAIIVAGDVFDTGSPPSYARTLVVNTGHLVVLAGNHDS-------------------------VATLNE-----SRDIM------------AFLNTTVVAS--A-GH--------------------------AP------------QILPDGTPGLCPIPF-LRPRDIITSQ--------EKQQHLLAAITDYYQQHYADACKLR---GDQPLPIIATGHLTTVGASKS--DA-VRDIYIGTLDAFPAQNFPPA------------------------------------------------------------DYIAL--------------------GHI---HRAQIIG-GMEHVRYCGSPIPL--SFDECGKSKYNLESVENLNVPVTQPMAVLKDLASITAQLEQQ-E---PPVWL-----DIEI-D-EYLHDIQRKIQALTE------- | |||||||||||||
7 | 6h8qA | 0.13 | 0.08 | 0.65 | 0.32 | MRFsearch | --IRQVFERFKTLDVRIHSIQVLTEASSL-----------DSEILIISSLMFDERSKFLSTVAKFLARVIEVGPVVQVGIFIKILNDSLIYHLKDTQAAEFLSPYISTHLKTICNLLISLPLFYDLLNAASIESADILCPLLESFIYETELKKITDKTIKAFMDSSKVDMKYDIFAKFIHHIHHFEKKEL------QEKFLNQIATLKIH----------LKKFLQEKMDYKDLTCSLYELYIN--KLTILGRDYPVDEELLQLFLNNFVSR---------IPIMFQDFDDSTAQEINFKMLVLLATWNLEKWREIIEKVR-------------------------------------------DYEISKDLRSVWKPIAAIGRLNTLVISLAATNETFENIN---------------SLFYLKW----SACTSLMDIIVAIKIFELKLPAD---------------------------ATTWRYSMSE-----------QFPFYLHDNASKVLLKIFL--------------------------------------------------------------------YLESLFAKQ----------------ETGFFENIETEFLLFTVKLKGLMKL--- | |||||||||||||
8 | 6v9iC | 0.11 | 0.10 | 0.92 | 0.98 | FFAS-3D | ---KGPAKIHQALKEDILEFIKQARVLSHQDDTA-LLKAYIVEWRKFFTQCDILPKPFCDTWNESIFSNIKNRLQDSAMKLVHAERESYVNLCSNPEDKLQIYRDNFEKYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLETRRECNSVEALMECCVNALVT-SFKETILAECQGMIKRNETEKLHLMFSLMDKVPGIEPMLKDLEEH-IISAGLADMVAAAETITTDSEKYVEQLLTLFNRF--SKLVKEAFQDDLTARDKAYKAVVNDKCPELLANYRKTPLSKKLTSEEIEAKLKEVLLVLKYHLTRRLILDISADSEIEENMVEWLR---------------------------EVGMPADYVNKLARMFQDIKVSEDLNQAFKEMHKALP-ADSVNIKILNAGAWSRSSEKVFVSL-----PTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDL----EVTTFQLAVLFAWNQRPREKISFENLKLPDAELRRTLWSLVFPKLKRQVLLYEPQVNSPKDFTE----GTLFSVNQEFSLIKNAKV--QKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMRKKISNAQLQTELVEILKMIKEQIEWL-- | |||||||||||||
9 | 6vr4A | 0.11 | 0.10 | 0.84 | 0.82 | SPARKS-K | EYHNDFVKQHNKSEQLQNRLFDLYWAVLT-------------NEKTYGDLITPIFPHVKDEIKRVFGDN-SKQTGENLKFHD--PLYQLKLKFTYAG-GKSGVGITANLVDHNRSKGIDQFNQYNLKEYSEEKIKDTISAFLNAFVD-NAKDPYINDGVAFLIRAGVHPDWIISFIPVLRELADFTQRYESKIIPKKSSFDIIVEKYETIRAFSID-------------------LDVLKTFKGFQRLNESVQGSGILKNKIKNLYVSEQTQQKGSNHFKKYHNNGKIT-----SLGTQVKNTLLFTDDILNNNPSLFLLGSKPIQDLVNSISNN--LVDSRGGSRGLLTN-----------------EDVGKLFYKEVYKYAYIKDTIFDLVNYKTEDNFFIENTVYENSFGIT-NKNKS---------------VDFQDRLYRSAYDLENP---ELANKFISSFLNGNKLIDI----KEYIPYQWFLENDIRSFIESKNTGLKDSSESLEEQFIKNNSDSNI--LA----PIKSIKG---IKSKHVFELPINDKTKRYITKEEVLPYRLKAYRSGVYVRTNKLGFEDPKSF---------LSIKEYKFGTRT-GGNFTGELTKQELVYTNQWVNENIT | |||||||||||||
10 | 4wvfC | 0.09 | 0.07 | 0.82 | 1.04 | CNFpred | QVVSTFYQGGVQQKQAQEILTKFQDNP----DAWQKADQILQF-STNPQSKFIALSILDKLITRKWK-LLPNDHRIGIRNFVVGMIISMCQDDEVFKTQKNLINKSDLTLVQILKQEWPPEFIPELIGSSS-SSVNVCENNMI----------VLKLLSEEVFDFQMTQAKALHLKNSMSKEFEQIFKLCFQVLEQG-LIVATLESLLRYIPYRYIYENILELLSTKFMTSPDTRAITLKCLTEVSNLKIPNDLIKRQTVLFFQNTLQQIATS-VMPVTADLKATYANNGNDQSFLQDLAMFLTTYLARN-RALLESDESLRELLLNAHQYLI------------------QLSKIE---ERELFKTTLDYWHNLVADLF-EEICSQLRLVIIE--NMVRPE------EVLVVENDEGEIVREFV--KESDTIQLYKSEREVLVYLTHLNVIDTEEIMISKLARQIDGS--EWSWHNINTLSWAIGSISGT----------MSEDTEKRFVVTVIKDLLD-----------LCVKKRGKDNKAVVASDIMYVVGQYPRFLK--------------AHWNFLR----TVILKLFEF-------------------MHET-HEGVQDMACDTFIKIVQKCKY | |||||||||||||
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References: | |
1. | Wei Zheng, Yang Li, Chengxin Zhang, Robin Pearce, S. M. Mortuza, Yang Zhang. "Deep-learning contact-map guided protein structure prediction in CASP13." Proteins: Structure, Function, and Bioinformatics, 87: 1149-1164 (2019). |