>PF05482 (538 residues) MDILFIKLNVCSDLIGKGAIGNIAWLNKFCAAFHEFASKFKMHLPDVAPKDDMEGKIRIH VETLFLCFIQVVTCITQLERTINMENTLGKRVKLRLTRTHFVDRIEWCLRRLQASLYHLS EEAIASSGVKLEDLSFVEVLDVALDKLETFNEIVHDVDTESRLDSENPQLCIEVNHIVRH ALAFANVALESDKKAMTVICETVLDECSVFEHNFDHHNLGERKLEALSIQRALYSLETYL NEALLRLIFTSFSDADEISVNRLKNVLQKCEISKDVEKRICDFDINMDRIQQIGVFAIAF ASDVKTKTIIRSCLASLESLDSCIVPAFQLQTSTSASYHANILEHHFKEELMVFRNVIHE IINSRALIDIYLDMLAESIDGAEKLYQKQRLLQVAQMGNVLFQHFHLKVNYQELCADECG KRLHQDFVVILGECQAILELTVPVDPKRVLKRFKILYSVLAKLRDVCGGSIREGSVCPNQ NSHMISKNLKHNSIRQQTFVKPGKEFTHDKSSNNKSSNSLLHESDLISFQITEILQIN |
Rank | PDB hit | ID1 | ID2 | Cov | Norm. Zscore | Threadingprogram | 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 | | | | | | | | | | | | | | | | | | | | | | | | | | | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Seq | MDILFIKLNVCSDLIGKGAIGNIAWLNKFCAAFHEFASKFKMHLPDVAPKDDMEGKIRIHVETLFLCFIQVVTCITQLERTINMENTLGKRVKLRLTRTHFVDRIEWCLRRLQASLYHLSEEAIASSGVKLEDLSFVEVLDVALDKLETFNEIVHDVDTESRLDSENPQLCIEVNHIVRHALAFANVALESDKKAMTVICETVLDECSVFEHNFDHHNLGERKLEALSIQRALYSLETYLNEALLRLIFTSFSDADEISVNRLKNVLQKCEISKDVEKRICDFDINMDRIQQIGVFAIAFASDVKTKTIIRSCLASLESLDSCIVPAFQLQTSTSASYHANILEHHFKEELMVFRNVIHEIINSRALIDIYLDMLAESIDGAEKLYQKQRLLQVAQMGNVLFQHFHLKVNYQELCADECGKRLHQDFVVILGECQAILELTVPVDPKRVLKRFKILYSVLAKLRDVCGGSIREGSVCPNQNSHMISKNLKHNSIRQQTFVKPGKEFTHDKSSNNKSSNSLLHESDLISFQITEILQIN | |||||||||||||||||||
1 | 1st6A | 0.13 | 0.11 | 0.84 | 1.17 | DEthreader | EVKIIRVCKGILEYLTVAEVVLVTYTKNLGPGMTKMAKMIDERQQELT--------HQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKKIEEALKNRNFTVEKMSAEINEIIRVLQL-T-SWDEDAWASKDVKAAVHLEGKIEQAQRWIDNPT-------V--DDRGVGQAAIRGLVAEGRRLANVMMGPYRQDLLAKCDRVDQLAAQLADLARGEGSPQARAIAAQLQDSLKDLKARMQEAMTQEVSDVFSDTT-TPIKLLAVAATPDNREEVFEERAANFENHAARLGATAEKAAAVTANKTTVEGIQATVKSARELTPQVVSAARILRNNAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMAQLVGASIARRANRILLVAKREVENSEDPKREAVKAASDELSKTISPMVMDAKAVIDGLQKSFLDSGYRILGAVAKVREAF-QPQEPDF--------------------------------------------------------------- | |||||||||||||
2 | 4iggA | 0.09 | 0.07 | 0.79 | 1.00 | DEthreader | ------------------------------------AA-RQQELKDV-------------HRDQMAAARGILQKNVPILYASQACL-HPDVAAYKANR-LIY-QL--A--------------------QGGGGGELAYALNNFDKQIIVD-PL-----S-FSEERFRPSLEERLESIISGAALMADSCTRDRRERIVAECNAVRQALQDLLSEYMGNARDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLE-TNVPLLVLIEAAKNGN-EKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAKSLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDLDTAGAIRGRAARVIHVVTSMDEPGVTEKVLEATKLLNTVMPRFTEQVAPMDENEFIDASRLVYDGIRDIRKAVLM---IRTP-------------LDAEV-SKW--DD-----SGNDIIVLAKQMCARMKLGTISKYQKSQGM---- | |||||||||||||
3 | 4iggA | 0.10 | 0.09 | 0.92 | 6.11 | HHpred | MADVYKLLVQLKVVEDGIEQDLGIQYKALKPEVDKLNIMAAKRQQELK-----D---VGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDAS-QHQGGGGGELAYALNNFDKQIVDPLSFSE--------ERFRPSLEERLESIISGAALMADSTRDDRRERIVAECNAVRQALQDLLSEYMGGRSDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETN-VPLLVLIEAAKN-GNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALAKPQSLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGIRGRAARVIHVVTSEMDNYEYTELEATKLLSNTMPRFTEQVEAAVEDPQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPGQ-----SARAIMAQLPQEQKAKSKLDVSKWDD---------------SGNDIIVMEMTDFTR-- | |||||||||||||
4 | 4iggA | 0.11 | 0.10 | 0.96 | 1.10 | DisCoVER | VYKLLVQLKVVEDGILKLRGNELGQYKALKPEVDKLNIMAAKRQ--QE------LKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQAASDDASQ-HQG-GGGGELAYALNNFDKQI--IV-DP----LSF-SEEFRPSLEERLESIISGAALMADCTRDDRRERIVAECNAVRQALQDLLSEYAGRKEDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLET-NVPLLVLIEAAK-NGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAKPSAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVIVTSEMKVLEATKLLSNVMPRFTEQVEAAVEALSAQPM-DENEFIDASRLVYDGIRDIRVLMIVASFEKKLLAMCIMMEMTDFTTVIAAKKIARIALYCHQLNICSKVKAGVDSAMSLIQAAKNLMNAV- | |||||||||||||
5 | 4iggA | 0.11 | 0.09 | 0.82 | 0.62 | MRFsearch | --KLLVQLKVVEDGILKLEQDLGIQYKALKPEVDKLNIMAAKRQQELK--------DVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDASQH-QGGGGGELAYALNNFDKQIIV-------------EERFRPSLEERLESIISGAALMADSSRDDRRERIVAECNAVRQALQDLLSEYMGNRSDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLET-NVPLLVLIEAAKN-GNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALQSKLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGIRGRAARVIHVVTSEMDNYEPKVLEATKLLSNTVMRFTEQVEAAVEALQPMDENEFIDASRLVYDGIRDIRKAVLM--------------------------------------------------------------------- | |||||||||||||
6 | 4iggA | 0.11 | 0.10 | 0.95 | 2.13 | SPARKS-K | VYKLLVQLKVVEDGILKLRNDLGIQYKALKPEVDKLNIMAAKRQQEL--------KDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQA-TASDDASQHQGGGGGELAYALNNFDKQIIVDP--LSFSEERF-----RPSLEERLESIISGAALMADCTRDDRRERIVAECNAVRQALQDLLSEYMGERSDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETN-VPLLVLIEAAKN-GNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALPQSLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDAGAIRGRAARVIHVVTSEMDNYEPGVLEATKLLSNVMPRFTEQVEAAVEALSPMDENEFIDASRLVYDGIRDIRKAVLMIRTPGQSA-RAIMAQLPEQKAKIAEQVASFQEEKSKLDASKWDDS--------GNDIIVLAKQMCMIMM | |||||||||||||
7 | 4iggA | 0.10 | 0.10 | 0.96 | 1.74 | MAPalign | VYKLLVQLKVVEDGILKLEQDLGIQYKALKPEVDKLNIMAAKRQQEL--------KDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQ-ATASDDASQHQGGGGGELAYALNNFDKQIIVDP-------LSFSEERFRPSLEERLESIISGAALMADCTRDDRRERIVAECNAVRQALQDLLSEYMGNRSDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLET-NVPLLVLIEAAKNG-NEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDAGAIRGRAARVIHVVTSEMDNYEPVYTEKVLEATKLLSNVMPRFTEQVEAAVPMDENEFIDASRLVYDGIRDIRKAVLMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCHQLNI--- | |||||||||||||
8 | 4iggA | 0.10 | 0.10 | 0.97 | 0.97 | CEthreader | VYKLLVQLKVVEDGILKLEQDLGIQYKALKPEVDKLNIMAAKRQQELK--------DVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQ-ATASDDASQHQGGGGGELAYALNNFDKQIIV-------DPLSFSEERFRPSLEERLESIISGAALMADCTRDDRRERIVAECNAVRQALQDLLSEYMGERSDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETN-VPLLVLIEAAKN-GNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALQSKLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVIHVVTSEMLEATKLLSNTVMPRFTEQVEAAVEAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFT | |||||||||||||
9 | 4iggA | 0.11 | 0.10 | 0.96 | 1.14 | MUSTER | VYKLLVQLKVVEDGILKLRNAG---EQDLGIQYKALKPEVDKLNIMAA-KRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQA-TASDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEER-------FRPSLEERLESIISGAALMADSTRDDRRERIVAECNAVRQALQDLLSEYMGERSDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLET-NVPLLVLIEAAKN-GNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALQSKLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVIHVVTSEMDVYTEKVLEATKLLSNTVMPRFTEQQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKL------DAEVSKWDDSGNDIIVMEMTDFTRGK | |||||||||||||
10 | 4iggA | 0.11 | 0.11 | 0.96 | 4.59 | HHsearch | VYKLLVQLKVVEDGILKLEQDLGIQYKALKPEVDKLNIMAAKRQQELK-----D---VGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDASQ-HQGGGGGELAYALNNFDKQIVDPLSFSE--------ERFRPSLEERLESIISGAALMADSSRDDRRERIVAECNAVRQALQDLLSYMGNERSDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETN-VPLLVLIEAAK-NGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALAKPQSLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGIRGRAARVIHVVTSEMDNYEYTELEATKLLSNTMPRFTEQVEAAVEDPQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPGSARGN-DIIVLAKQMCMIMMEMTDFTRGKGP--LKNTSDSKLGHDSACKQDLLAYQLNICSKVK | |||||||||||||
|
|
References: | |
1. | Wei Zheng, Yang Li, Chengxin Zhang, Robin Pearce, S. M. Mortuza, Yang Zhang. "Deep-learning contact-map guided protein structure prediction in CASP13." Proteins: Structure, Function, and Bioinformatics, 87: 1149-1164 (2019). |