>PF05474 (582 residues) MKSIILFVLSLLLILEKQAAVMGQKGGSKGQLPSGSSQFPHGQKGQHYFGQKDQQHTKSK GSFSIQHTYHVDINDHDWTRKSQQYDLNALHKATKSKQHLGGSQQLLNYKQEGRDHDKSK GHFHMIVIHHKGGQAHHGTQNPSQDQGNSPSGKGLSSQCSNTEKRLWVHGLSKEQASASG AQKGRTQGGSQSSYVLQTEELVVNKQQRETKNSHQNKGHYQNVVDVREEHSSKLQTSLHP AHQDRLQHGPKDIFTTQDELLVYNKNQHQTKNLSQDQEHGRKAHKISYPSSRTEERQLHH GEKSVQKDVSKGSISIQTEEKIHGKSQNQVTIHSQDQEHGHKENKISYQSSSTEERHLNC GEKGIQKGVSKGSISIQTEEQIHGKSQNQVRIPSQAQEYGHKENKISYQSSSTEERRLNS GEKDVQKGVSKGSISIQTEEKIHGKSQNQVTIPSQDQEHGHKENKMSYQSSSTEERRLNY GGKSTQKDVSQSSISFQIEKLVEGKSQIQTPNPNQDQWSGQNAKGKSGQSADSKQDLLSH EQKGRYKQESSESHNIVITEHEVAQDDHLTQQYNEDRNPIST |
Rank | PDB hit | ID1 | ID2 | Cov | Norm. Zscore | Threadingprogram | 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |||||||||||||
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Seq | MKSIILFVLSLLLILEKQAAVMGQKGGSKGQLPSGSSQFPHGQKGQHYFGQKDQQHTKSKGSFSIQHTYHVDINDHDWTRKSQQYDLNALHKATKSKQHLGGSQQLLNYKQEGRDHDKSKGHFHMIVIHHKGGQAHHGTQNPSQDQGNSPSGKGLSSQCSNTEKRLWVHGLSKEQASASGAQKGRTQGGSQSSYVLQTEELVVNKQQRETKNSHQNKGHYQNVVDVREEHSSKLQTSLHPAHQDRLQHGPKDIFTTQDELLVYNKNQHQTKNLSQDQEHGRKAHKISYPSSRTEERQLHHGEKSVQKDVSKGSISIQTEEKIHGKSQNQVTIHSQDQEHGHKENKISYQSSSTEERHLNCGEKGIQKGVSKGSISIQTEEQIHGKSQNQVRIPSQAQEYGHKENKISYQSSSTEERRLNSGEKDVQKGVSKGSISIQTEEKIHGKSQNQVTIPSQDQEHGHKENKMSYQSSSTEERRLNYGGKSTQKDVSQSSISFQIEKLVEGKSQIQTPNPNQDQWSGQNAKGKSGQSADSKQDLLSHEQKGRYKQESSESHNIVITEHEVAQDDHLTQQYNEDRNPIST | |||||||||||||||||||
1 | 5jcss | 0.08 | 0.08 | 1.00 | 1.68 | SPARKS-K | TVSSLRQLGRKIQNLINELSKYMGCHDSIVKIHLGEQTYTSGDKPGTFEWRAGVATAVKEGRWVLIEDIDKAPTDVLSILLSLLEKRELTIPSRGETVKAANGVRINEDHQKDSSNKIYNLNMRIWNVIELEEPSEEDLTHILAQKFPILTNPKLIDSYKNVKSIYMNTKFISLNKGAHTLDILFKNNGINKPDQLIQSSVYDSIFSEAADCFAGAIGEFKALEPIRISLFLTQHVPTLENLDDSIKIGRAVLLKEKLNIQKKSMNSTLFAFTNHSLRLMEQISVCIQKMLAKKLTVINVSQQTETGDTVAVPIQENFETLFNATFSLKKNEKFHKMLHRCFNKNQWKNVVKLWNEAYKMAQSILKITNTENENENAKKKKRRLNTHEKKLLLDKWADFNDSVKKFEAQSSSIENSFFNFVEGSLVKTIRAGEWLLLDENLATADEPDSRSILLSEKGDAEPIKAHPNPATDVPMGIRSRHSPERDITDLLSIIDKYIGKYSVSDEWVGNDEAKKLSDNNTIVDGSNQKPHFSIRTLTRTLLYVTDIIHIYGLRRSLYTLLDQKSEAIIEKFTLGRLKNVKS | |||||||||||||
2 | 3chnS | 0.11 | 0.10 | 0.93 | 1.19 | MUSTER | -KSPIF----------GPEEVNSVEGNS--SITCYYPPTSVNRHTRKY--CRQGARGG------------CITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTIN--PFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQ-QAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGR-HSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGSSVA-PYNRKESKSIKYWCLEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKHFPCKFSSYEKYWCKNTGCQALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEGWQGHFYGETAAVYEERKAAGSRDVSLAKADAAPDEKVLDSGFREIENKAIQDPR-------- | |||||||||||||
3 | 2xkxA | 0.06 | 0.05 | 0.80 | 0.77 | DisCoVER | GTEGE--ME--YE-EI--TL-ERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDRLNDSILF---------------VNVDVEVTHSAAVEALK----EAG----------SIVRLYVMRR---------------------------------KP--PAVMEIKLIKGGLGFSIAGGVGNQDNSIYVTKIIEGAAHKDG-RLQIGDKI---LAVNSVGLEDVMHEDAVAALK-N--TYDVVYLKVAKPAPPDIPREP----RRIVI--HRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSLRNASHEATIIAQYKPEEYSRFIHDL---------REQLMNSSLG-SGTASLRSNPKRGFY---IRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVIGFIPSKRRVERREWSRLKAKDWGSSSGQGREDSVLSYETV-------------TQ-MEVHYARPIIILG-PTKDRANFGSCVIETSVSVRVAEQGKHCILLQLHPIAIFI-RPRIALEQEFTECFSAIVEGDSFEIYKVVILSGP-YIWVP- | |||||||||||||
4 | 4hvtA | 0.05 | 0.03 | 0.63 | 0.67 | DEthreader | -------------------ETIFYDQRKTPYGVIRYVYNFWM--NPQGLWRREVLIDFDKSKAYRSGGKD-----------E--MF--FRE-WDLEKKDFVK-NG-FEPITNSGKLL-----EGKFTY-------------I-NL--------VLHKNEITSSLYPN-SLYIWKRESI-A---KDSSSLIFISANK--------YILDTLQKINMPSDAT--L--------------QGSF-KEYVF--WLLR------------KAGSLVALHF----------------------------LKILFTPTVFNFISTT-FLA-YDNVAKVVTFTL-TKPV--VL-----K-L-PYQ-NAI--FGM---------TIENSIV----------HELKIIRKALY---LEQKEPYFLVY----LLEA-YGGF-QVINAPYKNVVSVLANIRGGGPHKSAQGKRTAFNFSLVSVAILDMYWVTEYGDPELIAPLLITDSVLD-------QRVHPWH-G---RIFEY--AQ--KTYF-LES--K--D--S---------GHGSGSDL-KESANYFINLYTFF---- | |||||||||||||
5 | 5ifeA1 | 0.08 | 0.05 | 0.66 | 0.49 | CEthreader | -----------------------------------------------------------TGISFAIHGNFSGTKQQEIVVSRGKILELLRPDPNTGKVHTLLTVEVFGVIRSLMAFRLTGGTKDYIVVGSDSGRIVILEYQPSKNM---------------FEKIHQETFGKSGCRRIVPGQFLAVDPKGRAVMISAIEKQKLRDAAARLTISSPLEAHKANTLVYHVVGVDVGFENPMFACLEMDYEEADNDPTGEAAANTQQTLTFYELDLGLNHVVRKYSEPLEEHGNFLITVPGGSDGPSGVLICSENYITYKNFGDQ-----PDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFFFLAQTEQGDIFKITLETDEDMV----TEIRLKYFDTVPVAAAMCVLKTGFLFVASEFGNHYLYQIAHLGDDDEEPEFSSAMPLEDTFFFQPRPLKNLVLVDELDS------------------------------------------------------------------------------------------------------------------ | |||||||||||||
6 | 4m57A | 0.08 | 0.07 | 0.94 | 0.82 | EigenThreader | RADITSLLKALELSGLALLRWAGKEGAADASALEVVRALGREGQHDAVCALLDETPLPPGS-----------RLDVRAYTTVLHALSRAGRYERALELFAELRRQGVAPTLVTYNVVLDVYGR-----------GRSWPRIVALLDERAAGVEPDGFTASTVIAACSRDGLVDEAVAFFEDLKARGHAPSVVTYNALLQVFGKAGNYTEALRVLGEECQPDAVTYNELAGTYARAGFFEEAARCLDTASKGLLPNAFTYNTVTAYGNVGKVVPNVNTYNLVLGLGSGCTPNRVTWNTLAVSGKTYNTLIAAYGRCGSRTNAFKYNETSAGFTPCITTYNALLNVLSRQGDWSTAQSIVSKRTKGFKPNEQSYSLLLQCYAKGGNVAGIAAIENEVYILRTLVIANFKCRRLDGEARGYNPDLVIFNSLSIYAKNGYSKATEVFDSIKRSGLSPDLITYNSLDYAKCSESWEAEKILNQLKCSQTKPDVVSYNTVINGFCKQ--------GLVKEAQRVLSEVADGAPCAVTYHTLVGGYSSLEFSEAREVIGYVQ-----HGLKPELTYRRVVESYCRAKRF | |||||||||||||
7 | 6kacH | 0.44 | 0.01 | 0.03 | 0.34 | HHpred | --FILLFAAFLLIILEIYNS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | |||||||||||||
8 | 2pffB | 0.16 | 0.03 | 0.16 | 0.48 | MRFsearch | ---------------------------------------------------------ETTTQFKATHILDFG------------------------------------------------TGVRVIVAGTLDINPDDDYGFKQGGGGGGGGGGGGGYKTSKAAQDVWNRAD--------------------------------------------------------------------------------NHFKDT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YGFSILDIV-----------------------------------------------INNPVNLTIHFGG-------------------- | |||||||||||||
9 | 3cnfB | 0.10 | 0.08 | 0.82 | 0.42 | FFAS-3D | IQNVLLLFFSRWY--PVEYGIFVQRGATAGEFEFSGRNEKWDQALYLSEGFLRTDDLAIAANF-----PRASRNPQTYIPYTNQRGTVTNEFASRFRTIVATLANVVDDMQKATRSCTKQWLRHLVVYATMSNFMLNFTNNFATHVAVVLYQSGVINGPASTYLRE------NEVLVVMPDYYDVVSRFANANLQMNNNRYHESVLEIADIFDQADFQTSDAVRQLRALMPTLSTSQIRHAIERIAQITDVDSLTLRFLGTLTRSLKMQNAQIRRIRPDGRYDDQIDIEAFRWSRYFLDELQLRRLSVGLRLGVRIMYLTDDDPDPDFVPDVPEGYVAVQYAHRLFSSSLANKRNRVTYTHPPTGPTGRPHVHMTINERAGMSKLVADNVDILDIEYTAEVMTPSEGYTQHVDAESIMTAPKGKLF------HLQFMDGLLRPEASGEDMRLPLQPISVARSMRAIVNHNEVDRPREMDTGT-------------------LSRNG----DLLYSPVANGQ------------------------------------------------------------- | |||||||||||||
10 | 1zvoC | 0.07 | 0.06 | 0.84 | 1.50 | SPARKS-K | -------------------------------------------RLQLQESGPGLVKPSETLSLTCIVSRQPPGKGLEWIGGVY-----YTGSIYYNPSLRGRVTISVDTSRNRSMSAADTAMYYCARGN------PPPYYDIGTGSDDGIDVWGQGTTVHVSSA-------PTKAPDVFPIISGCRHPKDNSPVVLAC--LITGYHPTSVTVTWYMGTQSQPQRTFPEIQRRDSYYMTSSQLSTPLQQWRQGEYKCVVQHTASKSKKEIFRWPESPKAQASSVPTAQPQAEGSLAKATTAPAT---TRNTGRGGEEKKKEKEKEEQEERETK---TPECPSHTQPLGVYLLTPAVQDLWLRD--------KATFTCFVVGSDLKDAHLTWEVAGKVPTGGVEEGLLERHSNGSQSQHSRLTLPRSLWNAGTSVTCTLNHPSL--PPQRLMALREPAAQAPVKLSLNLLASSDPPEAA--------------SWLLCEVSGFSPPNILLMWLEDQREVNTSGFAPARPPPQPGSTTFWAWSVLRVPAPPSPQPATYTCVVSHEDSRTLLNASRSLEVSYVTDH | |||||||||||||
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References: | |
1. | Wei Zheng, Yang Li, Chengxin Zhang, Robin Pearce, S. M. Mortuza, Yang Zhang. "Deep-learning contact-map guided protein structure prediction in CASP13." Proteins: Structure, Function, and Bioinformatics, 87: 1149-1164 (2019). |