>PF04409 (520 residues) MNESVLIGKSERFLDQIKRKEISLTDIVSPEKFLSLYTYLQNNLDSLHDMREIMEIKGYT APYRSINKYGRPLTGETKAEDMYDISRHTQYFRMNAAAKKNILDRVKSAISSHKIAVGHL EEFATLECSSCHKKYRGHEIALLTPGKCECGQNDLKLHVNQEGVYRLGIIPFLPLSGDYM VKLSELSPRSREAFRRIVRILKQEKRGIVKTVSLIIKVMEDNRWVRKRVTIDAQDDANYE KEIRSQYGPNARIEMMQFHRKKPSIINDKHMQTALSLGYVKYAENRILQFLPDLLEKTLH NKDKVEEYQEAVEISKIKANKYDTGDDPESLKNFYLKMELKDRGLLDKDGKPEKTLQNDL KEKNLLEKSLFHEMPRIYILWDILRYYLTTSYDRRNKYSGPFPYLRPGLDTNQIKAFQDF EVEVVKIMQEYLSEDITYIPHMGRVLSKKFSVEKKMKGLHLQMGPALGAALLSSEANIPV EKSAQLFSIKVEDVSKGKETLSTLQRPTSSRAKQFMAMMK |
Rank | PDB hit | ID1 | ID2 | Cov | Norm. Zscore | Threadingprogram | 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 | | | | | | | | | | | | | | | | | | | | | | | | | | | |||||||||||||
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Seq | MNESVLIGKSERFLDQIKRKEISLTDIVSPEKFLSLYTYLQNNLDSLHDMREIMEIKGYTAPYRSINKYGRPLTGETKAEDMYDISRHTQYFRMNAAAKKNILDRVKSAISSHKIAVGHLEEFATLECSSCHKKYRGHEIALLTPGKCECGQNDLKLHVNQEGVYRLGIIPFLPLSGDYMVKLSELSPRSREAFRRIVRILKQEKRGIVKTVSLIIKVMEDNRWVRKRVTIDAQDDANYEKEIRSQYGPNARIEMMQFHRKKPSIINDKHMQTALSLGYVKYAENRILQFLPDLLEKTLHNKDKVEEYQEAVEISKIKANKYDTGDDPESLKNFYLKMELKDRGLLDKDGKPEKTLQNDLKEKNLLEKSLFHEMPRIYILWDILRYYLTTSYDRRNKYSGPFPYLRPGLDTNQIKAFQDFEVEVVKIMQEYLSEDITYIPHMGRVLSKKFSVEKKMKGLHLQMGPALGAALLSSEANIPVEKSAQLFSIKVEDVSKGKETLSTLQRPTSSRAKQFMAMMK | |||||||||||||||||||
1 | 6vacA | 0.09 | 0.08 | 0.97 | 1.00 | FFAS-3D | -KLMDALKHASNMLGELRTSML------SPKSYYELYMAISDELHYLEVLYELVQCRGVQHPLRGLLQCTRNILPDEGLLNFAEMNKLWVRMQKRERERQELRILVGTNLVAQEYLMECIIQVFPDECAELHQNVNVKNIIIHREDGPGIPAEIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYETTVEIFNKLNLEHIATTRLLKIPVDTYNNILTVLKLKHPLFEYFDYESRKSMSCYVLSNVLD---YNTEIVSQDQVDSIMNLVSTLIQFADEQSLVGRFIHLLRSDDQQYLILNTARKHFGAG-----GNQRIRFTLPPLVFAAYQLAFRYKENSQMDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHETVAYEFMSQAFSLYEDEIAAITLIIGTFERMKCFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWRVMECLKKALKIANQQVQLFIEILNRYIYFYEKTIQVLNQLIQKIR | |||||||||||||
2 | 4fgvA | 0.10 | 0.08 | 0.79 | 1.09 | CNFpred | LDVVDMEQIMTEKLARQVDG-----SEWSWHNCNVLCWAIG-LVTVIKDLLGLTEMKRGKDNKAVVAS-----------NIMYIVGQYPRFLKAHWKFLKTVVNKLFEFMHSHEGVQDMACDTFIKIAKQCRRHFVALQPSE-------------------NEPFIEEIIRNI------GKITCDLTPQQVHTFYEACGYMV--------------SAQG-----------NRNQQERLLAELMAIPNAAW-DEIIKAATMNPGILHEPDTIKIIIMKTNVSACSSIGPYFFPQIGRLYNMLQMYAATSQLISEAVARDGEIAT-KMPKVRGLRTIKKEILKL---------VETFVEKAEDLQAVRSQMIP-----GLLDSVLVDYNRNVP---------------ARDAEVLKAMT----VIITRLQGLMEDQVPAI--MENVFECTLDMINKD-----AEYPEHRVEFFNLLRAINLYCFPALLKLDNRQFKFVIDSCMWASKHNRDVETAGLNMCL | |||||||||||||
3 | 6d03E | 0.08 | 0.06 | 0.70 | 0.74 | DisCoVER | --STNTTDNIDYFD--I----S-D----ESNYY--LI--S-------------QL---RPHFSNIYFEFKYASYHTEIKRYEDIHKTKVNSLLNEASRAIINILENPKKEAFRGCLLNKNRKNLDQIKKINNEIRDLL-----EKLKCSQDC-----QTNVYKIYLVDFMNYFIKYLSGVDMIRKIEKQIDVTINAIKFTQKEIDRFHLQKVHSIDQVTALSDGVKPKQV-----TKNRLKEYYFNI--GNYYSIFKFGKDSLMLNALIHKEKIVHNLLGELFGHLEERISKLIDSE-YFITESNNIISQSEETLKLAEEDLKKYNDLRESIIYIQS-YV--SSI------K-SAYRYNVLEKDSVESKQAQKKVDELLSIIDSI------------------SYSNFSVAENFQ-------------------------KMKDYYIEKLKI-KILIEAIKKYQQHVEEL-------------------------------------------------- | |||||||||||||
4 | 3vthA | 0.08 | 0.05 | 0.62 | 0.67 | DEthreader | ARR--KRYGKPFAV-VK-YCIV---SPEEERLLLSIVLLGVMLPIVMTS-GN--V------SEEPICKDEAKLAFLNNRDIVN-R--I-------------------------DD-SVTSFNAGAER---------I-------------------RRARGYAPQPILLAVGKNTFCMFISHHI-G---DLDN-AF-YY---IEYKVDPEVVAH-DMH---------------LDLPKI------EVQ-HHHAHIASCMA------EHNL---GIAYDGTGYGTGNV-----PGNE-LAI-K--KI-YR-TA---------------FI-FDNISFYKNFV-EQV------DSRELDIILKQIDR-KINTA-YV-SSMGRFFDAEGQAAMELESLM-E------------------------------RYVIDPLIRQIYYEKSYISAKFHNVVNFTYDLAIVVLSGGSFQNRYLL-RRLIEKLSLSGFEV--YSNSKVPCNDGGI-------------- | |||||||||||||
5 | 6k8nA | 0.08 | 0.08 | 0.98 | 0.59 | CEthreader | NNYYLIIAEKSKAAKKIAEALSEKPILCRKYNV--------SYWIIKDHNSSKYVIVPAAGHLFGLKGESGFPVYDADWKPLWEIDKNSYYTKRYYQLISSLSKYALGFINAIEGSVIGYLIIKNLGDIKKAKRMKFSALTKSDILSAFRNISALDYDMINAGIARHKIDISLQDFAKKRVILSAGRVQSPTLVQVVNSEIERNLFIPLPKFTVSIIVKIKDYSLNIKVNKEFEKITEAKEFLNKLINKTVKVVEVENRVRLLERPSPFNLTDLQIEAGRIYSPYNVERIAEDLYLDGLTNSQKIPSTISIYNIIKGLENSSYRKLVDLVRKITGGKYVVKQGIKDDPAHPAIHPTGEAPKNLPNSKFKIYDLIFLGSVSADAKLSNTIYTLKVSDFPLEFTVSYTKILERNWLDIYHFHNVKEDKPIFLSKGDEGKIVKLGFYIAEILNKFFPDIVDVRMTADMESKLEMIKTGKVLESKVIKENIEKLNKFIEEYKVNKDKVGESLAKALGLIKIVKC | |||||||||||||
6 | 3k9fA | 0.08 | 0.05 | 0.65 | 0.67 | EigenThreader | MSLEDIMGERFGRYSKYIIQDRIRDGLKPVQRRILYSMNKDSNT-------------FDKSYSAKSVGNIMGNFHPHGDSSIYDAMVRMS-------------------------------QLVEMHGNNGS-----------MDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPAAVYMIDHPTAKIDKLMEFLDEIKKAYETGKGRVVVRSTEIEKLKGGQIVITEIPYEINKANLVKKIDDVRVNLRIAIELNFNMVFGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGL--IRVISILDEVIALIRASEN----------------KADAKENLKVSYDFTEEQAEAIVTVLQEEEAELREKIAMLAAIIGD---------------------------ERTMYNLMKKELREVKKKFATPRLSSLE---------------------------------------------------------------------------------- | |||||||||||||
7 | 6gylW | 0.15 | 0.05 | 0.33 | 0.50 | HHpred | -----IDDIVKNLLKFVVRGFYGGSFVLVLDAIDDLKQLLSINKTELGPLIARLRSDRLISIHKQREYPPNRVYYYVKYPHAIDAIKW-----K----VHQVVQRLKDDLDKN-------SEPNGYMCPICLTKYTQLEAVQLTEFLCLCDEP-LVEDDSGK----------------KNKEKQDKLNRLMDQIQPIIDSLKKIDDSRI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | |||||||||||||
8 | 6gmhQ | 0.11 | 0.09 | 0.80 | 0.58 | MRFsearch | --DQEKRDIAKGHLKKVTEQY-----PDDVEAWIELAQILQGALSAYGTATRILQEKVADVPPEILNNVGALHFRLGNLGEAKK--YFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYEAMC----------------------------EFHEAE-----------------KLYKNILREH-PNYVDCYLRLGAMARDKG--NFYEAS---------DWFKEALQINGPGQKKFERILKQPS-----------------TQSDTYSMLALGNVWLQTHQDRALAIYKQVLRNVLAHKGYFREARDVFAQVREATADI--SDVWLNLAHIYVEQK---------------QYISAVQMYENCLRKFYKHQNTEVVLYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDE-KSNLKEVLNAVKELELAHRYFSYLSKLALAATEARQCSDLLSQAQYHVARARKQDEEERLREKEEQKKLLEQRAQYVEKTKNILMF-- | |||||||||||||
9 | 5flzB | 0.10 | 0.09 | 0.89 | 0.98 | FFAS-3D | --EEDILKYVSYTLLATTSALFPFDHEQIQNFESGLLHLIFEAGLLYQSLGYKVEKFRMLNISPMKKAL---------IIEISEELQ--NYTAFVNNLVSSGLKSLYREIYENIIRLRIYCRF-------------------------------TEHLEELSGDTFLIELNIFKSHGDIRKIATNLFNSMISLYYEYLMNWLTKGLLRATYGEFFIAENYHIPIEFNQERVPAFIPKELAYKI-FMIGKS--YIFLEKYCKEVQWTNEFSKKYHVLYQIINDQYSEIVNHTNQILNQKFHYRDVVFAMDALIEKANDILATPSDSLPNYKLTRV-LQEAVQLSSLRHLMNILYPPLSLVLNVNRPFGRKEYLRIFNFLWRFKKNNYFYQKEMLKSNDIIRI-------NKLSRISILRTQFQQFNSKMESYYLNCIIE--ENFKEMTRKLQIDELESVHNTFLTNILSHKLFATQP--YPTSLVLLLNSVLGKFNTNLKEIVSQYKNFKDRLYIFRADLK | |||||||||||||
10 | 6r9tA | 0.10 | 0.09 | 0.92 | 0.76 | SPARKS-K | AASQSFLQPGGKMVAAAKASVPTIQDQASAMQLSQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSVLKPLPGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQAGIAARDVAGGLRSLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEKAAGH-----------PGDPESQQRLAQVAKAVTQALNRCVSCLPGQRD--VDNALRAVGLLSDS-------LPSTGTFQEAQSRLNEAAAGQAATELVQASRGTPQDLSGRFGQDFSTFLEAGVERAQVVSNLKGISMSSSKLLLAAKALSQLAAAARAVTDMCTQQAPNALRELETVRELLENPVQPINDMSYLDSVMENSKVLGEAMTGISQNATASKALCGFTEAAAQAAYLVGVSDPNSQAGQQGLVE---PTQFARANQAIQMACQSLGEPGCTAATIVAKHTSALCNSCRLASA------------------RTTNPTAKRQFVQSAKEVANSTANLVKTIAFTEENRAQCRAATA | |||||||||||||
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References: | |
1. | Wei Zheng, Yang Li, Chengxin Zhang, Robin Pearce, S. M. Mortuza, Yang Zhang. "Deep-learning contact-map guided protein structure prediction in CASP13." Proteins: Structure, Function, and Bioinformatics, 87: 1149-1164 (2019). |