>PF04109 (501 residues) WNWVNVYNLDAFLQEAYYYYEGKGFYSIALSRGLNLLTVGFVIGFSTFLLGCVDYSRIRP DKVTRLSEVVVKRCVSRFSGFTLLFFVLFTAFFAWQLVSYVLSMMRLVDMYRFYTYLLHI PDEDIQTISWPEVVRRIAAIRESNPLTALSSNAAAHQSTTTAKLDAHDIANRIMRQENYL IALFNKELLDLRVPLPEALKRIPMFRVDEDGKGRTLTRALEWNLRFCLMEYLFDESGRVR KVFLKSKNRAILIEGLRRRFIFMGILNAIFAPFIVLYLLMYSFFRYFEEYHKNPSNIGGR AYTPYAQWKFREFNELPHLFKRRLNESYPTASMYIGQFPNEKVTLIVRFVAFIAGSFAAV LLLASVVDPDLFLHFEITPHRTVLFYITVFGSILAVARGMIPEENRVFDPELLMSEVVQY THYMPDEWKGELHSKKVHAEFGELFQMKVVIFAQELLSVLLTPFVLWYSLPPCAPAIVDF FREFTVHVDGLGYVCSFAVFD |
Rank | PDB hit | ID1 | ID2 | Cov | Norm. Zscore | Threadingprogram | 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 | | | | | | | | | | | | | | | | | | | | | | | | | | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Seq | WNWVNVYNLDAFLQEAYYYYEGKGFYSIALSRGLNLLTVGFVIGFSTFLLGCVDYSRIRPDKVTRLSEVVVKRCVSRFSGFTLLFFVLFTAFFAWQLVSYVLSMMRLVDMYRFYTYLLHIPDEDIQTISWPEVVRRIAAIRESNPLTALSSNAAAHQSTTTAKLDAHDIANRIMRQENYLIALFNKELLDLRVPLPEALKRIPMFRVDEDGKGRTLTRALEWNLRFCLMEYLFDESGRVRKVFLKSKNRAILIEGLRRRFIFMGILNAIFAPFIVLYLLMYSFFRYFEEYHKNPSNIGGRAYTPYAQWKFREFNELPHLFKRRLNESYPTASMYIGQFPNEKVTLIVRFVAFIAGSFAAVLLLASVVDPDLFLHFEITPHRTVLFYITVFGSILAVARGMIPEENRVFDPELLMSEVVQYTHYMPDEWKGELHSKKVHAEFGELFQMKVVIFAQELLSVLLTPFVLWYSLPPCAPAIVDFFREFTVHVDGLGYVCSFAVFD | |||||||||||||||||||
1 | 6wqzC | 0.30 | 0.21 | 0.72 | 1.00 | DEthreader | -PWHHIENLDLFFSRVYNLHQKNGFTCMLIGEIFELMQFLFVVAFTTFLVSCVDYDILFANKVPDAFLPVCSARIQENG-SLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEH-QICI---------HK-RELTELDIYHRILRFQNYMVALVNKSLLPLRF-------RLPGL-G----EAVFFTRGLKYNFELILFWSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWS---------------------QSRLNRGYKPAS-----------------------------------------------------------------------------VFCPEQLLRVI-------------------AFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMS | |||||||||||||
2 | 6wqzC | 0.29 | 0.21 | 0.73 | 1.00 | DEthreader | PWHHIE-NLDLFFSRVYNLHQKNGFTCMLIGEIFELMQFLFVVAFTTFLVSCVDYDILFAN-VDAFLPAVCSARIQENGS-LITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQ-KEHQIC---------IHK-RELTELDIYHRILRFQNYMVALVNKSLLPLRFRL-P--GL-----GE----AVFFTRGLKYNFELILFWSLFL-NEWSLKAEYKRGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLK-REPGALGARCWSL-YGRCYLRHFNELEHELQSRLNR-----------------------------------------------------------------------------------------VILAHIH-------------------LFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMD | |||||||||||||
3 | 6wqzC | 0.35 | 0.33 | 0.94 | 17.20 | HHpred | -PWHHIENLDLFFSRVYNLHQKNGFTCMLIGEIFELMQFLFVVAFTTFLVSCVDYDILFANK-VTLPDAFLPACSARIQGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQIC-----------IHKRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPG------------LGEAVFFTRGLKYNFELILFGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDV-LAVE-----HVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMD | |||||||||||||
4 | 6slfA | 0.06 | 0.03 | 0.61 | 0.64 | DisCoVER | HQHPEMSETSKRIAEELEKL-------------------------------GLE--PQNIGVTGQVAVIKN----GEGPSVAFRA-----------------------D---F--DA-----------------------L---PITENTYSADPELGMMHACGHDLHTTALLGAVRALVENKDLW----SGTFIAVHQPGEGARHMVIAAPDVCFA--Q----------------HVF------------NE--DP--AF--GY-VF--TP--G--------------------RFLTAASNWRIHIHGEGGHGPHLTK-DPIVVAASIITKLQTIVSVDPNE-VAV-VTVGSI-EG-------------------GKSTNSIP-YTVTL-GV-NTR-ASNDELSVQAIKRIVIECQAAIPEAVQLMAQFREFFGEDQAV--EIPPLSGSEDYPFIPPSVMWG-WS--GFAAGS-DA--PG----NHTDFAPLEGTQIL- | |||||||||||||
5 | 7jloA | 0.34 | 0.32 | 0.94 | 0.88 | MRFsearch | --WHHIENLDLFFSRVYNLHQKNGFTCMLIGEIFELMQFLFVVAFTTFLVSCVDYDILFANVKVTLPDAFLQVCSARENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQICIH-----------KRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPGLG------------EAVFFTRGLKYNFELILFWGLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDVLA------VEHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMD | |||||||||||||
6 | 7jloA | 0.34 | 0.32 | 0.94 | 3.79 | SPARKS-K | -PWHHIENLDLFFSRVYNLHQKNGFTCMLIGEIFELMQFLFVVAFTTFLVSCVDYDILFANVKVTLPDAFLPVCSARINGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQIC-----------IHKRELTELDIYHRILRFQNYMVALVNKSLLPLR------------FRLPGLGEAVFFTRGLKYNFELILFGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDVLAV------EHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMD | |||||||||||||
7 | 6wqzC | 0.34 | 0.32 | 0.94 | 2.11 | MAPalign | -PWHHIENLDLFFSRVYNLHQKNGFTCMLIGEIFELMQFLFVVAFTTFLVSCVDYDIL-FANKVTLPDAFLPACSARINGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQIC-----------IHKRELTELDIYHRILRFQNYMVALVNKSLLPLRFRL------------PGLGEAVFFTRGLKYNFELILFWGLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDVLA------VEHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMD | |||||||||||||
8 | 6wqzC | 0.34 | 0.32 | 0.94 | 1.52 | CEthreader | -PWHHIENLDLFFSRVYNLHQKNGFTCMLIGEIFELMQFLFVVAFTTFLVSCVDYDILFANKVTLPDAFLPAQVCSQENGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQIC-----------IHKRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPG------------LGEAVFFTRGLKYNFELILFWSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDVLAV------EHVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMD | |||||||||||||
9 | 5mz61 | 0.09 | 0.09 | 0.96 | 0.67 | MUSTER | EYFQGLAKYQRTACKMFITWQTLRKEAMECRDREIFASIPAKLCFFYFYNG--ELCRAV----VCLLDYIDLS-DDTLAKEAALRWLMFLTELIEKKLKTWKSSKDMFSATEFAMNYLKKSEYRVEM--LEKLMKLRDKVKSDPTCSTLSNVPVGSALRECEFPDRVSHIQEAALKSDSLVRNRIPGLASSQFDNSVNASIWPFLDGHQEDSNYYVGSTIAWHFEMRRECALVNVTTAQTRDSM-SAMILNLRVALKSFFRVLQTTNTLAYYSSIIEEAG--SEKNAKLMRVSCVNLLSSNTIYPLHSSFAAEYMMSYAIHSDFQLSIKHFNDEFARIRERGMSSQVLMHIIQNEIFGMCVIRWLTKKLDALKIVRYLQQRTTDMILAVTQLGRQLEFPMECNYSWMRPRLAMRNEMNHYGHILYREWR-----CRLFAYVGRTSPWEAAYAWAESTQIGARNAVQSRLTMSGHDRFKTCVQSMPDEM----TLVQIAMAD | |||||||||||||
10 | 6wqzC | 0.34 | 0.32 | 0.94 | 7.55 | HHsearch | -PWHHIENLDLFFSRVYNLHQKNGFTCMLIGEIFELMQFLFVVAFTTFLVSCVDYDILFANK-VTLPDAFLPACSARIQGSLITILVIAGVFWIHRLIKFIYNICCYWEIHSFYLHALRIPMSALPYCTWQEVQARIVQTQKEHQIC-----------IHKRELTELDIYHRILRFQNYMVALVNKSLLPLRFRLPG------------LGEAVFFTRGLKYNFELILFGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWIGIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSRLNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDEDVL-AVE-----HVLTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQLFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMD | |||||||||||||
|
|
References: | |
1. | Wei Zheng, Yang Li, Chengxin Zhang, Robin Pearce, S. M. Mortuza, Yang Zhang. "Deep-learning contact-map guided protein structure prediction in CASP13." Proteins: Structure, Function, and Bioinformatics, 87: 1149-1164 (2019). |