sequence (NextProt isoform, UniProt entry, common name, gene name) | COFACTOR (MF in red, BP in blue, CC in green) | UniProt GO (reviewed in black; IEA-only in grey) UniProt annotation score (1 to 5) NextProt GO (GOLD in black; SILVER in grey) | Tissue-specific protein expression (Human Protein Atlas) | Tissue-specific RNA expression (GTEx Portal) | |
1 | >NX_Q8TBR7-2|FA57A_HUMAN FAM57A GN=FAM57A MLLTLAGGALFFPGLFALCTWALRRSQPGWSRTDCVMISTRLVSSVHAVL ATGSGIVIIRSCDDVITGRHWLAREYVWFLIPYMIYDSYAMYLCEWCRTR DQNRAPSLTLRNFLSRNRLMITHHAVILFVLVPVAQRLRGDLGDFFVGCI FTAELSTPFVSLGRVLIQLKQQHTLLYKVNGILTLATFLSCRILLFPFMY WSYGRQQGLSLLQVPFSIPFYCNVANAFLVAPQIYWFCLLCRKAVRLFDT PQAKKDG chromosome location: 732412-742972 (17p13.3) Database cross references: | MF: GO:0016740_(1.00)_transferase_activity GO:0050291_(0.99)_sphingosine_N-acyltransferase activity GO:0042277_(0.21)_peptide_binding GO:0004985_(0.21)_opioid_receptor_activity GO:1901338_(0.20)_catecholamine_binding GO:0050780_(0.20)_dopamine_receptor_binding GO:0008227_(0.20)_G-protein_coupled_amine_receptor activity GO:0004952_(0.20)_dopamine_neurotransmitter receptor_activity GO:0042802_(0.18)_identical_protein_binding GO:0020037_(0.18)_heme_binding GO:0019899_(0.18)_enzyme_binding GO:0009055_(0.18)_electron_carrier_activity GO:0005506_(0.18)_iron_ion_binding GO:0003796_(0.18)_lysozyme_activity GO:0001609_(0.18)_G-protein_coupled_adenosine receptor_activity BP: GO:0044763_(0.99)_single-organism_cellular_process GO:0032502_(0.69)_developmental_process GO:0044767_(0.64)_single-organism_developmental process GO:0048856_(0.59)_anatomical_structure_development GO:1901564_(0.57)_organonitrogen_compound metabolic_process GO:0044237_(0.57)_cellular_metabolic_process GO:0006629_(0.57)_lipid_metabolic_process GO:0048869_(0.55)_cellular_developmental_process GO:0016043_(0.54)_cellular_component_organization GO:0007420_(0.54)_brain_development GO:0021952_(0.53)_central_nervous_system projection_neuron_axonogenesis GO:0001654_(0.53)_eye_development GO:0006672_(0.46)_ceramide_metabolic_process GO:0046467_(0.42)_membrane_lipid_biosynthetic process GO:0046513_(0.41)_ceramide_biosynthetic_process CC: GO:0005887_(1.00)_integral_component_of_plasma membrane GO:0005886_(1.00)_plasma_membrane GO:0044444_(0.99)_cytoplasmic_part GO:0043229_(0.99)_intracellular_organelle GO:0043227_(0.99)_membrane-bounded_organelle GO:0005783_(0.98)_endoplasmic_reticulum GO:0097458_(0.37)_neuron_part GO:0042995_(0.37)_cell_projection GO:0098590_(0.29)_plasma_membrane_region GO:0044463_(0.29)_cell_projection_part GO:0005794_(0.29)_Golgi_apparatus GO:0005737_(0.29)_cytoplasm GO:0043005_(0.25)_neuron_projection GO:0030430_(0.25)_host_cell_cytoplasm GO:0044456_(0.22)_synapse_part | UniProt annotation: GO:0005886_plasma_membrane GO:0005515_protein_binding GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ NextProt annotation: GO:0005515_protein_binding | ||
2 | >NX_A6NGC4-1|TLCD2_HUMAN TLC domain-containing protein 2 GN=TLCD2 MAPTGLLVAGASFLAFRGLHWGLRRLPTPESAARDRWQWWNLCVSLAHSL LSGTGALLGLSLYPQMAADPIHGHPRWALVLVAVSVGYFLADGADLLWNQ TLGKTWDLLCHHLVVVSCLSTAVLSGHYVGFSMVSLLLELNSACLHLRKL LLLSRQAPSLAFSVTSWASLATLALFRLVPLGWMSLWLFRQHHQVPLALV TLGGIGLVTVGIMSIILGIRILVNDVLQSRPHPPSPGHEKTRGTRTRRDN GPVTSNSSTLSLKD chromosome location: 1702790-1710438 (17p13.3) Database cross references: | MF: GO:0016740_(0.86)_transferase_activity GO:0050291_(0.76)_sphingosine_N-acyltransferase activity GO:0005216_(0.59)_ion_channel_activity GO:0009881_(0.55)_photoreceptor_activity GO:0051377_(0.05)_mannose-ethanolamine phosphotransferase_activity GO:0008757_(0.05)_S-adenosylmethionine-dependent methyltransferase_activity BP: GO:0044763_(0.97)_single-organism_cellular_process GO:0008152_(0.90)_metabolic_process GO:0071704_(0.89)_organic_substance_metabolic process GO:0044238_(0.89)_primary_metabolic_process GO:0044237_(0.89)_cellular_metabolic_process GO:0006643_(0.76)_membrane_lipid_metabolic_process GO:0006672_(0.73)_ceramide_metabolic_process GO:0044765_(0.61)_single-organism_transport GO:0050794_(0.60)_regulation_of_cellular_process GO:0006811_(0.60)_ion_transport GO:0034220_(0.58)_ion_transmembrane_transport GO:0019538_(0.58)_protein_metabolic_process GO:0044267_(0.56)_cellular_protein_metabolic process GO:0050896_(0.55)_response_to_stimulus GO:0006464_(0.54)_cellular_protein_modification process CC: GO:0044464_(1.00)_cell_part GO:0016021_(1.00)_integral_component_of_membrane GO:0016020_(1.00)_membrane GO:0044424_(0.81)_intracellular_part GO:0044444_(0.77)_cytoplasmic_part GO:0005783_(0.75)_endoplasmic_reticulum GO:0005886_(0.55)_plasma_membrane GO:0005793_(0.24)_endoplasmic_reticulum-Golgi intermediate_compartment GO:0005794_(0.04)_Golgi_apparatus GO:0005789_(0.03)_endoplasmic_reticulum_membrane GO:0005737_(0.03)_cytoplasm | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ | ||
3 | >NX_O43149-1|ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand domain-containing protein 1 GN=ZZEF1 MGNAPSHSSEDEAAAAGGEGWGPHQDWAAVSGTTPGPGVAAPALPPAAAL LEPARLREAAAALLPTPPCESLVSRHRGALFRWLEERLGRGEESVTLEQF RELLEARGAGCSSEQFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQG ELSHIIRQLQACSLVPGFTDIFSESKEGLDIHSSMILRFLHRNRLSSAVM PYPMLEHCNNMCTMRSSVLKESLDQLVQKEKESPGDLTRSPEMDKLKSVA KCYAYIETSSNSADIDKMTNGETSSYWQSDGSACSHWIRLKMKPDVVLRH LSIAVAATDQSYMPQQVTVAVGRNASDLQEVRDVHIPSNVTGYVTLLENA NVSQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYW SLLTSLVTASMETNPAFVQTVLHNTQKALRHMPPLSLSPGSTDFSTFLSP NVLEEVDSFLIRITSCCSTPEVELTLLAFALARGSVAKVMSSLCTITDHL DTQYDASSLILSMASVRQNLLLKYGKPLQLTLQACDVKGKEDKSGPENLL VEPWTRDGFLTETGKTRASTIFSTGTESAFQVTQIRIMVRRGGIGAQCGL VFAYNSSSDKFCAEEHFKRFEKYDKWKLQELRQFVKSRIGCSSDDLGEDD PIGWFELEEEWDEADVKLQQCRVAKYLMVKFLCTRQESAERLGVQGLTIS GYLRPARAEAEQSVTCAHCRKDTEESVCGATLLLRTLQFIQQLAHDLVQQ KESGLKYKSFLDFAGLDLQIFWNFYSKLKQNPREECVSAQTLLLQLLQSC FSVLQGDVLAASEEEKAPIQSPKGVEAAKELYTHLCDVVDKVDGDSVPME ILKQEVRNTLLNGAAIFFPNRQTRRNHLFTMMNVTEQEHKQSLQLTFRSL CTYFSDKDPGGLLLLPEKNDLAKMNISEVLAVMDTLVSVAARECELLMLS GAPGEVGSVLFSLFWSVQGSLLSWCYLQLKSTDSGAKDLAVDLIEKYVGQ FLASMRAILESLFSQYSGKTIVERLCNSVFSMAARQLVIFLLDFCTLDIP HCVLLREFSVLTELLKKLCSGPEGGLRKLDVETWQQEQPVVLHTWTKESA HNYENNCHEVSVFVSPGATYFEVEFDDRCETEKRYDYLEFTDARGRKTRY DTKVGTDKWPKKVTFKAGPRLQFLFHSDSSHNEWGYKFTVTACGLPDVAV SWGLDLQLLVSRLMGRLASQCMALKSVRQLGSNMVVPQAKMALVLSSPLW KPVFRHQVCPELELEASWPTHPHRNSKEVKNIPDDPCRHFLLDFAQSEPA QNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPD LYEKLQKYVNSGGKIALSEEFAQVYSLADGIRIWMLEMKQKSLMSLGNEA EEKHSSEATEVNPESLAKECIEKSLLLLKFLPTGISSKESCEKLETADET SHLQPLNKRQRTSSVVEEHFQASVSPTEAAPPATGDQSPGLGTQPKLPSS SGLPAADVSPATAEEPLSPSTPTRRPPFTRGRLRLLSFRSMEEARLVPTV KEKYPVLKDVMDFIKDQSLSHRSVVKVLSLRKAQAQSILEVLKITQHCAE SLGQPHCFHPPFILFLLELLTCQKDFTNYFGHLEGCGADLHKEIRDTYYQ LVLFLVKAVKGFSSLNDRSLLPALSCVQTALLHLLDMGWEPNDLAFFVDI QLPDLLMKMSQENISVHDSVISQWSEEDELADAKQNSEWMDECQDGMFEA WYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQC SDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMNCNVCD DFDLCYGCYAAKKYSYGHLPTHSITAHPMVTIRISDRQRLIQPYIHNYSW LLFAALALYSAHLASAEDVDGEKLDPQTRSSATTLRSQCMQLVGDCLMKA HQGKGLKALALLGVLPDGDSSLEDQALPVTVPTGASEEQLEKKAVQGAEL SEAGNGKRAVHEEIRPVDFKQRNKADKGVSLSKDPSCQTQISDSPADASP PTGLPDAEDSEVSSQKPIEEKAVTPSPEQVFAECSQKRILGLLAAMLPPL KSGPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLLPA EVDAAVIKVLSAKHNLFAAGDSSIVPDGWKTTHLLFSLGAVCLDSRVGLD WACSMAEILRSLNSAPLWRDVIATFTDHCIKQLPFQLKHTNIFTLLVLVG FPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKD YQLVQKGGGQECGDSRAQLSQYSQHFAFIASHLLQSSMDSHCPEAVEATW VLSLALKGLYKTLKAHGFEEIRATFLQTDLLKLLVKKCSKGTGFSKTWLL RDLEILSIMLYSSKKEINALAEHGDLELDERGDREEEVERPVSSPGDPEQ KKLDPLEGLDEPTRICFLMAHDALNAPLHILRAIYELQMKKTDYFFLEVQ KRFDGDELTTDERIRSLAQRWQPSKSLRLEEQSAKAVDTDMIILPCLSRP ARCDQATAESNPVTQKLISSTESELQQSYAKQRRSKSAALLHKELNCKSK RAVRDYLFRVNEATAVLYARHVLASLLAEWPSHVPVSEDILELSGPAHMT YILDMFMQLEEKHEWEKILQKVLQGCREDMLGTMALAACQFMEEPGMEVQ VRESKHPYNNNTNFEDKVHIPGAIYLSIKFDSQCNTEEGCDELAMSSSSD FQQDRHSFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLG RFQTGFEILKQMLSEERVVPHLPLAKIWEWLVGVACRQTGHQRLKAIHLL LRIVRCCGHSDLCDLALLKPLWQLFTHMEYGLFEDVTQPGILLPLHRALT ELFFVTENRAQELGVLQDYLLALTTDDHLLRCAAQALQNIAAISLAINYP NKATRLWNVEC chromosome location: 4004445-4143020 (17p13.2) Database cross references: | MF: GO:0003824_(0.56)_catalytic_activity GO:0016740_(0.53)_transferase_activity GO:0004842_(0.32)_ubiquitin-protein_transferase activity GO:0004672_(0.13)_protein_kinase_activity GO:0044877_(0.12)_macromolecular_complex_binding GO:0043169_(0.12)_cation_binding GO:0009931_(0.12)_calcium-dependent_protein serine/threonine_kinase_activity GO:0005516_(0.12)_calmodulin_binding GO:0004683_(0.12)_calmodulin-dependent_protein kinase_activity GO:0046872_(0.11)_metal_ion_binding GO:0043130_(0.11)_ubiquitin_binding GO:0005509_(0.10)_calcium_ion_binding GO:0042802_(0.09)_identical_protein_binding GO:0008092_(0.09)_cytoskeletal_protein_binding GO:0003700_(0.09)_transcription_factor_activity, sequence-specific_DNA_binding BP: GO:0009987_(0.84)_cellular_process GO:0043170_(0.64)_macromolecule_metabolic_process GO:0044238_(0.63)_primary_metabolic_process GO:0044260_(0.61)_cellular_macromolecule_metabolic process GO:0019538_(0.61)_protein_metabolic_process GO:0065007_(0.50)_biological_regulation GO:0006464_(0.50)_cellular_protein_modification process GO:0050789_(0.49)_regulation_of_biological_process GO:0050794_(0.44)_regulation_of_cellular_process GO:0032446_(0.36)_protein_modification_by_small protein_conjugation GO:0016567_(0.35)_protein_ubiquitination GO:0044699_(0.31)_single-organism_process GO:0048518_(0.24)_positive_regulation_of biological_process GO:0042787_(0.23)_protein_ubiquitination_involved in_ubiquitin-dependent_protein_catabolic_process GO:0048522_(0.21)_positive_regulation_of_cellular process CC: GO:0044464_(0.91)_cell_part GO:0044424_(0.83)_intracellular_part GO:0043226_(0.65)_organelle GO:0043229_(0.62)_intracellular_organelle GO:0043227_(0.62)_membrane-bounded_organelle GO:0043231_(0.58)_intracellular_membrane-bounded organelle GO:0005634_(0.47)_nucleus GO:0005737_(0.46)_cytoplasm GO:0032991_(0.28)_macromolecular_complex GO:0043234_(0.27)_protein_complex GO:0044422_(0.24)_organelle_part GO:0044446_(0.23)_intracellular_organelle_part GO:0044444_(0.21)_cytoplasmic_part GO:0016020_(0.19)_membrane GO:0044428_(0.17)_nuclear_part | UniProt annotation: GO:0008270_zinc_ion_binding GO:0005509_calcium_ion_binding GO:0046872_metal_ion_binding UniProt annotation score: ◉◉◉◉◉ NextProt annotation: GO:0005509_calcium_ion_binding GO:0008270_zinc_ion_binding | ||
4 | >NX_Q2TAL5-1|SMTL2_HUMAN Smoothelin-like protein 2 GN=SMTNL2 MEPAPDAQEARTVREALGRYEAALEGAVRALHEDMRGLQRGVERRVAEAM RLAGPLARTVADLQRDNQRLQAQLERLTRQVEALGLASGMSPVPGTPGTP SPPPAPGVPDRAPRLGSARFASHATFSLSGRGQSLDHDEASESEMRKTSN SCIMENGHQPGAGPGDGPPEIAQNFSAPDPPRPRPVSLSLRLPHQPVTAI TRVSDRFSGETSAAALSPMSAATLGGLNPSPSEVITPWTPSPSEKNSSFT WSVPSSGYGAVTASKHSNSPPLVTPPQSPVSPQPPAITQVHRQGERRREL VRSQTLPRTSEAQARKALFEKWEQETAAGKGKGEARARLKRSQSFGVASA SSIKQILLEWCRSKTLGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDY NSLSPTQRQKNFELAFTMAENLANCERLIEVEDMMVMGRKPDPMCVFTYV QSLYNHLRRFE chromosome location: 4583999-4608319 (17p13.2) Database cross references: | MF: GO:0008092_(0.77)_cytoskeletal_protein_binding GO:0003779_(0.42)_actin_binding GO:1901363_(0.40)_heterocyclic_compound_binding GO:0097159_(0.40)_organic_cyclic_compound_binding GO:0050660_(0.37)_flavin_adenine_dinucleotide binding GO:0046983_(0.30)_protein_dimerization_activity GO:0042802_(0.30)_identical_protein_binding GO:0042803_(0.29)_protein_homodimerization activity GO:0003824_(0.29)_catalytic_activity GO:0019899_(0.28)_enzyme_binding GO:0017166_(0.28)_vinculin_binding GO:0051393_(0.25)_alpha-actinin_binding GO:0019904_(0.22)_protein_domain_specific_binding GO:0017016_(0.22)_Ras_GTPase_binding GO:0016705_(0.22)_oxidoreductase_activity,_acting on_paired_donors,_with_incorporation_or_reduction of_molecular_oxygen BP: GO:0044699_(0.86)_single-organism_process GO:0009987_(0.82)_cellular_process GO:0044763_(0.76)_single-organism_cellular_process GO:0016043_(0.70)_cellular_component_organization GO:0032502_(0.69)_developmental_process GO:0044767_(0.63)_single-organism_developmental process GO:0048856_(0.59)_anatomical_structure_development GO:0065007_(0.51)_biological_regulation GO:0050789_(0.47)_regulation_of_biological_process GO:0006996_(0.47)_organelle_organization GO:0007010_(0.45)_cytoskeleton_organization GO:0050794_(0.44)_regulation_of_cellular_process GO:1902589_(0.42)_single-organism_organelle organization GO:0048869_(0.41)_cellular_developmental_process GO:0030029_(0.41)_actin_filament-based_process CC: GO:0044464_(0.99)_cell_part GO:0044424_(0.97)_intracellular_part GO:0044422_(0.75)_organelle_part GO:0043226_(0.73)_organelle GO:0044446_(0.71)_intracellular_organelle_part GO:0043229_(0.70)_intracellular_organelle GO:0044444_(0.68)_cytoplasmic_part GO:0005737_(0.66)_cytoplasm GO:0016020_(0.52)_membrane GO:0043232_(0.51)_intracellular_non-membrane- bounded_organelle GO:0044430_(0.50)_cytoskeletal_part GO:0044425_(0.44)_membrane_part GO:0005856_(0.43)_cytoskeleton GO:0043227_(0.42)_membrane-bounded_organelle GO:0005886_(0.42)_plasma_membrane | UniProt annotation score: ◉◉○○○ | ||
5 | >NX_O14894-1|T4S5_HUMAN Transmembrane 4 L6 family member 5 GN=TM4SF5 MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLM GGFIGGGLMVLCPGIAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVLG AIYCLSVSGAGLRNGPRCLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPR VVPWNVTLFSLLVAASCLEIVLCGIQLVNATIGVFCGDCRKKQDTPH chromosome location: 4771884-4783213 (17p13.2) Database cross references: | MF: GO:0015370_(0.50)_solute:sodium_symporter_activity GO:0005326_(0.50)_neurotransmitter_transporter activity BP: GO:0048856_(1.00)_anatomical_structure_development GO:0044767_(1.00)_single-organism_developmental process GO:0044763_(0.76)_single-organism_cellular_process GO:2000227_(0.64)_negative_regulation_of pancreatic_A_cell_differentiation GO:2000077_(0.64)_negative_regulation_of_type_B pancreatic_cell_development GO:0090104_(0.64)_pancreatic_epsilon_cell differentiation GO:0031018_(0.64)_endocrine_pancreas_development GO:0042246_(0.36)_tissue_regeneration GO:0044765_(0.34)_single-organism_transport CC: GO:0016021_(1.00)_integral_component_of_membrane GO:0005887_(0.05)_integral_component_of_plasma membrane | UniProt annotation: GO:0005887_integral_component_of_plasma_membrane GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ | ||
6 | >NX_Q7Z5L0-1|VMO1_HUMAN Vitelline membrane outer layer protein 1 homolog GN=VMO1 MERGAGAKLLPLLLLLRATGFTCAQTDGRNGYTAVIEVTSGGPWGDWAWP EMCPDGFFASGFSLKVEPPQGIPGDDTALNGIRLHCARGNVLGNTHVVES QSGSWGEWSEPLWCRGGAYLVAFSLRVEAPTTLGDNTAANNVRFRCSDGE ELQGPGLSWGDFGDWSDHCPKGACGLQTKIQGPRGLGDDTALNDARLFCC RS chromosome location: 4785285-4786433 (17p13.2) Database cross references: | MF: GO:0016787_(0.53)_hydrolase_activity GO:0008061_(0.36)_chitin_binding GO:0004568_(0.36)_chitinase_activity GO:0004551_(0.17)_nucleotide_diphosphatase activity GO:0004035_(0.17)_alkaline_phosphatase_activity GO:0030246_(0.15)_carbohydrate_binding GO:0004930_(0.14)_G-protein_coupled_receptor activity BP: GO:0065007_(0.36)_biological_regulation GO:0048856_(0.35)_anatomical_structure_development GO:0050794_(0.32)_regulation_of_cellular_process GO:0071711_(0.25)_basement_membrane_organization GO:0033334_(0.25)_fin_morphogenesis GO:0033333_(0.25)_fin_development GO:0006032_(0.25)_chitin_catabolic_process GO:0043569_(0.12)_negative_regulation_of_insulin- like_growth_factor_receptor_signaling_pathway GO:0051965_(0.10)_positive_regulation_of_synapse assembly GO:0007422_(0.10)_peripheral_nervous_system development GO:0007186_(0.10)_G-protein_coupled_receptor signaling_pathway GO:0001895_(0.07)_retina_homeostasis CC: GO:0070062_(1.00)_extracellular_exosome | UniProt annotation: GO:0070062_extracellular_exosome GO:0005576_extracellular_region UniProt annotation score: ◉◉◉○○ | ||
7 | >NX_A8MU93-1|CQ100_HUMAN Uncharacterized protein C17orf100 GN=C17orf100 MASARGAKQSSPRVGTTRYTETSTVRVETSSHRVETSSRRVETSQRRSEG PSLSPSGKRLPRILEASSRHVESSSQRTETTSRHVRASSLRVETSLHCAE SPTPRPSRPPARTKKRPDEMLLPKGHQGARALSQDRKASSCQPASQLPGG PIIFGFMETNHKSM chromosome location: 6651718-6693202 (17p13.1) Database cross references: | MF: GO:0003824_(0.46)_catalytic_activity GO:0016787_(0.27)_hydrolase_activity GO:0016740_(0.25)_transferase_activity GO:0052689_(0.23)_carboxylic_ester_hydrolase activity GO:0033040_(0.22)_sour_taste_receptor_activity GO:0005262_(0.22)_calcium_channel_activity GO:1901363_(0.20)_heterocyclic_compound_binding GO:0097159_(0.20)_organic_cyclic_compound_binding GO:0003881_(0.20)_CDP-diacylglycerol-inositol 3-phosphatidyltransferase_activity GO:0044822_(0.15)_poly(A)_RNA_binding GO:0008134_(0.15)_transcription_factor_binding GO:0003712_(0.15)_transcription_cofactor_activity GO:0001078_(0.15)_transcriptional_repressor activity,_RNA_polymerase_II_core_promoter_proximal region_sequence-specific_binding GO:0001047_(0.15)_core_promoter_binding GO:0000978_(0.15)_RNA_polymerase_II_core_promoter proximal_region_sequence-specific_DNA_binding BP: GO:0050794_(0.87)_regulation_of_cellular_process GO:0030308_(0.84)_negative_regulation_of_cell growth GO:0009987_(0.20)_cellular_process GO:0044699_(0.17)_single-organism_process GO:0044763_(0.14)_single-organism_cellular_process GO:0071704_(0.09)_organic_substance_metabolic process GO:0044710_(0.09)_single-organism_metabolic process GO:0044238_(0.09)_primary_metabolic_process GO:0044237_(0.09)_cellular_metabolic_process GO:0006810_(0.09)_transport GO:0048856_(0.08)_anatomical_structure_development GO:0006928_(0.08)_movement_of_cell_or_subcellular component GO:0051716_(0.06)_cellular_response_to_stimulus GO:0051017_(0.05)_actin_filament_bundle_assembly GO:0030048_(0.05)_actin_filament-based_movement CC: GO:0044464_(0.99)_cell_part GO:0044424_(0.98)_intracellular_part GO:0043226_(0.96)_organelle GO:0043227_(0.95)_membrane-bounded_organelle GO:0043229_(0.93)_intracellular_organelle GO:0043231_(0.92)_intracellular_membrane-bounded organelle GO:0005737_(0.88)_cytoplasm GO:0005634_(0.81)_nucleus GO:0043234_(0.77)_protein_complex GO:0016459_(0.76)_myosin_complex GO:0044444_(0.68)_cytoplasmic_part GO:0031988_(0.60)_membrane-bounded_vesicle GO:0016020_(0.59)_membrane GO:0042995_(0.44)_cell_projection GO:0016023_(0.44)_cytoplasmic,_membrane-bounded vesicle | UniProt annotation score: ◉○○○○ | ||
8 | >NX_Q8N2U0-1|TM256_HUMAN Transmembrane protein 256 GN=TMEM256 MAGPAAAFRRLGALSGAAALGFASYGAHGAQFPDAYGKELFDKANKHHFL HSLALLGVPHCRKPLWAGLLLASGTTLFCTSFYYQALSGDPSIQTLAPAG GTLLLLGWLALAL chromosome location: 7402975-7404137 (17p13.1) Database cross references: | MF: GO:0022892_(0.57)_substrate-specific_transporter activity GO:0017128_(0.55)_phospholipid_scramblase_activity GO:0003824_(0.47)_catalytic_activity GO:0008865_(0.45)_fructokinase_activity GO:0004454_(0.45)_ketohexokinase_activity GO:0042803_(0.04)_protein_homodimerization activity GO:0030955_(0.04)_potassium_ion_binding GO:0015081_(0.04)_sodium_ion_transmembrane transporter_activity GO:0009678_(0.04)_hydrogen-translocating pyrophosphatase_activity GO:0005509_(0.04)_calcium_ion_binding GO:0004427_(0.04)_inorganic_diphosphatase_activity GO:0000287_(0.04)_magnesium_ion_binding BP: GO:0009987_(0.59)_cellular_process GO:0046835_(0.57)_carbohydrate_phosphorylation GO:0006810_(0.46)_transport GO:0044351_(0.43)_macropinocytosis GO:0035725_(0.05)_sodium_ion_transmembrane transport GO:0015992_(0.05)_proton_transport CC: GO:0043227_(0.61)_membrane-bounded_organelle GO:0044464_(0.52)_cell_part GO:0070062_(0.51)_extracellular_exosome GO:0044424_(0.44)_intracellular_part GO:0016020_(0.41)_membrane GO:0044444_(0.34)_cytoplasmic_part GO:0044446_(0.26)_intracellular_organelle_part GO:0031090_(0.25)_organelle_membrane GO:0005743_(0.24)_mitochondrial_inner_membrane GO:0016021_(0.23)_integral_component_of_membrane GO:0043231_(0.10)_intracellular_membrane-bounded organelle GO:0005737_(0.10)_cytoplasm GO:0005783_(0.08)_endoplasmic_reticulum GO:0005886_(0.04)_plasma_membrane GO:0044437_(0.03)_vacuolar_part | UniProt annotation: GO:0070062_extracellular_exosome GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ | ||
9 | >NX_Q0P670-1|SPEM2_HUMAN Uncharacterized protein SPEM2 GN=SPEM2 MENQLWHNTVRCCNQYQESPHDAEDILLLLLGLIVLVNIGINVATMMWHG LQNALDKMIDWATQKNEIQASESPPSGPPDKAQDVHIHCILDPVQVKMSR PTQYSSFSCHHFSNHHSSSLLRCVRRRRRRHRRCRRRCCNHQQRPQNYRQ IPHSHSVFRNPHRSQKMSQLHRVPFFDQEDPDSYLEEEDNLPFPYPKYPR RGWGGFYQRAGLPSNVGLWGHQGGILASLPPPSLYLSPELRCMPKRVEAR SELRLQSYGRHGSQSRLWGNVEAEQWASSPPPPHRLPPNPSWVPVGHSPY PSVGWMLYDSWDQRRRGTEGFERPPASVSRNARPEAQGCREHHSPQSHQQ SLLGHAYGQSHRSPHPSTEPLGYSSQDPREVRRRAADWAEALPAWRPLTT SASLTVLDEASHQRTPAPSSVLVPHSSQPWPKVQAADPAPPPTMFVPLSR NPGGNANYQVYDSLELKRQVQKSRARSSSLPPASTSTLRPSLHRSQTEKL N chromosome location: 7425615-7427568 (17p13.1) Database cross references: | MF: GO:0003824_(0.43)_catalytic_activity GO:0005215_(0.25)_transporter_activity GO:0022892_(0.24)_substrate-specific_transporter activity GO:0008324_(0.23)_cation_transmembrane_transporter activity GO:0005261_(0.21)_cation_channel_activity GO:0046873_(0.19)_metal_ion_transmembrane transporter_activity GO:0022836_(0.18)_gated_channel_activity GO:0022843_(0.17)_voltage-gated_cation_channel activity GO:0005245_(0.16)_voltage-gated_calcium_channel activity GO:0016740_(0.13)_transferase_activity GO:1901363_(0.11)_heterocyclic_compound_binding GO:0097159_(0.11)_organic_cyclic_compound_binding GO:0016772_(0.11)_transferase_activity, transferring_phosphorus-containing_groups GO:0019899_(0.10)_enzyme_binding GO:0003676_(0.10)_nucleic_acid_binding BP: GO:0009987_(0.72)_cellular_process GO:0044699_(0.62)_single-organism_process GO:0065007_(0.57)_biological_regulation GO:0044763_(0.54)_single-organism_cellular_process GO:0050789_(0.48)_regulation_of_biological_process GO:0050794_(0.47)_regulation_of_cellular_process GO:0044767_(0.36)_single-organism_developmental process GO:0051179_(0.29)_localization GO:0065008_(0.28)_regulation_of_biological_quality GO:0006810_(0.28)_transport GO:0016043_(0.23)_cellular_component_organization GO:0008152_(0.22)_metabolic_process GO:0071704_(0.21)_organic_substance_metabolic process GO:0044238_(0.21)_primary_metabolic_process GO:0044237_(0.21)_cellular_metabolic_process CC: GO:0044464_(1.00)_cell_part GO:0044424_(0.95)_intracellular_part GO:0032991_(0.58)_macromolecular_complex GO:0043234_(0.57)_protein_complex GO:0005737_(0.53)_cytoplasm GO:0043226_(0.52)_organelle GO:0043229_(0.49)_intracellular_organelle GO:0044444_(0.46)_cytoplasmic_part GO:0044422_(0.40)_organelle_part GO:0044446_(0.39)_intracellular_organelle_part GO:0043227_(0.35)_membrane-bounded_organelle GO:0044428_(0.31)_nuclear_part GO:0043232_(0.31)_intracellular_non-membrane- bounded_organelle GO:0043231_(0.31)_intracellular_membrane-bounded organelle GO:0016020_(0.31)_membrane | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ | ||
10 | >NX_Q96T59-1|CDRTF_HUMAN CMT1A duplicated region transcript 15 protein GN=CDRT15 MFSCCFPTSRGCCFRNGGSESLFRRCRRRLIPHPRRLSPVVIRRIQVPQD SLGQALAGQATPEIPLGLQLHTVLVQEIQELIEAQTLAPGPCAEVRALPA PAAEPEPAWEEAPPERALELEGAPAKDQTNEELPEITEVPESIKRRLGRR VPAATPAPRGNLLLQAWMRVHSWASRLFAPNVLPGTGP chromosome location: 14235673-14236862 (17p12) Database cross references: | MF: GO:0003824_(0.69)_catalytic_activity GO:0030234_(0.57)_enzyme_regulator_activity GO:0016887_(0.55)_ATPase_activity GO:0003777_(0.55)_microtubule_motor_activity GO:0043178_(0.49)_alcohol_binding GO:0032934_(0.49)_sterol_binding GO:0015248_(0.49)_sterol_transporter_activity GO:0008047_(0.49)_enzyme_activator_activity GO:0071814_(0.40)_protein-lipid_complex_binding GO:0070405_(0.40)_ammonium_ion_binding GO:0042277_(0.40)_peptide_binding GO:0070325_(0.30)_lipoprotein_particle_receptor binding GO:0034190_(0.30)_apolipoprotein_receptor_binding GO:0004857_(0.30)_enzyme_inhibitor_activity GO:0071889_(0.19)_14-3-3_protein_binding BP: GO:0009987_(0.87)_cellular_process GO:0044699_(0.83)_single-organism_process GO:0044763_(0.79)_single-organism_cellular_process GO:0006810_(0.68)_transport GO:0050794_(0.64)_regulation_of_cellular_process GO:0016043_(0.57)_cellular_component_organization GO:0071702_(0.55)_organic_substance_transport GO:0006928_(0.55)_movement_of_cell_or_subcellular component GO:0007165_(0.54)_signal_transduction GO:0065008_(0.53)_regulation_of_biological_quality GO:0044707_(0.53)_single-multicellular_organism process GO:0051239_(0.52)_regulation_of_multicellular organismal_process GO:0055092_(0.49)_sterol_homeostasis GO:0045940_(0.49)_positive_regulation_of_steroid metabolic_process GO:0042157_(0.49)_lipoprotein_metabolic_process CC: GO:0044464_(0.97)_cell_part GO:0044424_(0.91)_intracellular_part GO:0016020_(0.79)_membrane GO:0044446_(0.73)_intracellular_organelle_part GO:0032991_(0.71)_macromolecular_complex GO:0044425_(0.62)_membrane_part GO:0044444_(0.60)_cytoplasmic_part GO:0043234_(0.54)_protein_complex GO:0043226_(0.54)_organelle GO:0016021_(0.54)_integral_component_of_membrane GO:0043229_(0.49)_intracellular_organelle GO:0043227_(0.49)_membrane-bounded_organelle GO:0044430_(0.47)_cytoskeletal_part GO:0005886_(0.47)_plasma_membrane GO:0043231_(0.44)_intracellular_membrane-bounded organelle | UniProt annotation score: ◉○○○○ | ||
11 | >NX_Q8NAA5-1|LR75A_HUMAN Leucine-rich repeat-containing protein 75A GN=LRRC75A MGTRQTKGSLAERASPGAAPGPRRERPDFWASLLLRAGDKAGRAGAGMPP YHRRVGMVQELLRMVRQGRREEAGTLLQHLRQDLGMESTSLDDVLYRYAS FRNLVDPITHDLIISLARYIHCPKPEGDALGAMEKLCRQLTYHLSPHSQW RRHRGLVKRKPQACLKAVLAGSPPDNTVDLSGIPLTSRDLERVTSYLQRC GEQVDSVELGFTGLTDDMVLQLLPALSTLPRLTTLALNGNRLTRAVLRDL TDILKDPSKFPNVTWIDLGNNVDIFSLPQPFLLSLRKRSPKQGHLPTILE LGEGPGSGEEVREGTVGQEDPGGGPVAPAEDHHEGKETVAAAQT chromosome location: 16441577-16492153 (17p11.2) Database cross references: | MF: GO:0030234_(0.37)_enzyme_regulator_activity GO:0004857_(0.36)_enzyme_inhibitor_activity GO:0005102_(0.20)_receptor_binding GO:0008134_(0.19)_transcription_factor_binding GO:0042974_(0.17)_retinoic_acid_receptor_binding GO:0003824_(0.16)_catalytic_activity GO:0097159_(0.14)_organic_cyclic_compound_binding GO:1901363_(0.13)_heterocyclic_compound_binding GO:0097367_(0.11)_carbohydrate_derivative_binding GO:0019899_(0.10)_enzyme_binding GO:0016740_(0.10)_transferase_activity GO:0019904_(0.09)_protein_domain_specific_binding GO:0004872_(0.08)_receptor_activity GO:0003676_(0.08)_nucleic_acid_binding GO:0008092_(0.07)_cytoskeletal_protein_binding BP: GO:0065007_(0.73)_biological_regulation GO:0050789_(0.73)_regulation_of_biological_process GO:0009987_(0.67)_cellular_process GO:0044699_(0.61)_single-organism_process GO:0050794_(0.54)_regulation_of_cellular_process GO:0071704_(0.48)_organic_substance_metabolic process GO:0044767_(0.48)_single-organism_developmental process GO:0044238_(0.47)_primary_metabolic_process GO:0043170_(0.47)_macromolecule_metabolic_process GO:0065009_(0.45)_regulation_of_molecular_function GO:0050790_(0.44)_regulation_of_catalytic_activity GO:0044237_(0.44)_cellular_metabolic_process GO:0051239_(0.43)_regulation_of_multicellular organismal_process GO:0044260_(0.43)_cellular_macromolecule_metabolic process GO:0019222_(0.40)_regulation_of_metabolic_process CC: GO:0044464_(1.00)_cell_part GO:0044424_(0.89)_intracellular_part GO:0043226_(0.76)_organelle GO:0043227_(0.72)_membrane-bounded_organelle GO:0005737_(0.69)_cytoplasm GO:0043229_(0.63)_intracellular_organelle GO:0044444_(0.60)_cytoplasmic_part GO:0044446_(0.59)_intracellular_organelle_part GO:0043234_(0.58)_protein_complex GO:0016020_(0.57)_membrane GO:0043231_(0.56)_intracellular_membrane-bounded organelle GO:0005886_(0.45)_plasma_membrane GO:0044421_(0.38)_extracellular_region_part GO:0005634_(0.37)_nucleus GO:0031988_(0.36)_membrane-bounded_vesicle | UniProt annotation score: ◉◉○○○ | ||
12 | >NX_Q5M775-1|CYTSB_HUMAN Cytospin-B GN=SPECC1 MRSAAKPWNPAIRAGGHGPDRVRPLPAASSGMKSSKSSTSLAFESRLSRL KRASSEDTLNKPGSTAASGVVRLKKTATAGAISELTESRLRSGTGAFTTT KRTGIPAPREFSVTVSRERSVPRGPSNPRKSVSSPTSSNTPTPTKHLRTP STKPKQENEGGEKAALESQVRELLAEAKAKDSEINRLRSELKKYKEKRTL NAEGTDALGPNVDGTSVSPGDTEPMIRALEEKNKNFQKELSDLEEENRVL KEKLIYLEHSPNSEGAASHTGDSSCPTSITQESSFGSPTGNQMSSDIDEY KKNIHGNALRTSGSSSSDVTKASLSPDASDFEHITAETPSRPLSSTSNPF KSSKCSTAGSSPNSVSELSLASLTEKIQKMEENHHSTAEELQATLQELSD QQQMVQELTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQER VKNEEPTTQEGKIIELEQKCTGILEQGRFEREKLLNIQQQLTCSLRKVEE ENQGALEMIKRLKEENEKLNEFLELERHNNNMMAKTLEECRVTLEGLKME NGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVARAEKDLLELSCNE LRQELLKANGEIKHVSSLLAKVEKDYSYLKEICDHQAEQLSRTSLKLQEK ASESDAEIKDMKETIFELEDQVEQHRAVKLHNNQLISELESSVIKLEEQK SDLERQLKTLTKQMKEETEEWRRFQADLQTAVVVANDIKCEAQQELRTVK RKLLEEEEKNARLQKELGDVQGHGRVVTSRAAPPPVDEEPESSEVDAAGR WPGVCVSRTSPTPPESATTVKSLIKSFDLGRPGGAGQNISVHKTPRSPLS GIPVRTAPAAAVSPMQRHSTYSSVRPASRGVTQRLDLPDLPLSDILKGRT ETLKPDPHLRKSPSLESLSRPPSLGFGDTRLLSASTRAWKPQSKLSVERK DPLAALAREYGGSKRNALLKWCQKKTQGYANIDITNFSSSWSDGLAFCAL LHTYLPAHIPYQELNSQEKKRNLLLAFEAAESVGIKPSLELSEMLYTDRP DWQSVMQYVAQIYKYFET chromosome location: 20009344-20319026 (17p11.2) Database cross references: | MF: GO:0008092_(0.53)_cytoskeletal_protein_binding GO:0046983_(0.45)_protein_dimerization_activity GO:0042802_(0.45)_identical_protein_binding GO:0019899_(0.45)_enzyme_binding GO:0003779_(0.43)_actin_binding GO:0042805_(0.42)_actinin_binding GO:0005198_(0.41)_structural_molecule_activity GO:1901363_(0.40)_heterocyclic_compound_binding GO:0097367_(0.40)_carbohydrate_derivative_binding GO:0097159_(0.40)_organic_cyclic_compound_binding GO:0032403_(0.40)_protein_complex_binding GO:0003824_(0.39)_catalytic_activity GO:0051015_(0.38)_actin_filament_binding GO:0044389_(0.38)_ubiquitin-like_protein_ligase binding GO:0003676_(0.38)_nucleic_acid_binding BP: GO:0009987_(0.84)_cellular_process GO:0044699_(0.82)_single-organism_process GO:0044763_(0.74)_single-organism_cellular_process GO:0016043_(0.67)_cellular_component_organization GO:0032502_(0.62)_developmental_process GO:0044767_(0.60)_single-organism_developmental process GO:0006996_(0.55)_organelle_organization GO:0065007_(0.51)_biological_regulation GO:0048856_(0.51)_anatomical_structure_development GO:1902589_(0.49)_single-organism_organelle organization GO:0050789_(0.48)_regulation_of_biological_process GO:0007010_(0.48)_cytoskeleton_organization GO:0050794_(0.47)_regulation_of_cellular_process GO:0048869_(0.46)_cellular_developmental_process GO:0051179_(0.45)_localization CC: GO:0044464_(0.98)_cell_part GO:0044424_(0.97)_intracellular_part GO:0044422_(0.78)_organelle_part GO:0044446_(0.76)_intracellular_organelle_part GO:0043226_(0.75)_organelle GO:0043229_(0.71)_intracellular_organelle GO:0044430_(0.66)_cytoskeletal_part GO:0044444_(0.64)_cytoplasmic_part GO:0016020_(0.59)_membrane GO:0043232_(0.54)_intracellular_non-membrane- bounded_organelle GO:0044425_(0.52)_membrane_part GO:0030054_(0.51)_cell_junction GO:0005856_(0.51)_cytoskeleton GO:0005886_(0.48)_plasma_membrane GO:0044459_(0.47)_plasma_membrane_part | UniProt annotation: GO:0016020_membrane GO:0005634_nucleus UniProt annotation score: ◉◉◉◉◉ | High: cells) center_cells) glandular_cells) glandular_cells) germinal_center_cells) peripheral_nerve) | |
13 | >NX_Q8N6N6-1|NATD1_HUMAN NATD1 GN=NATD1 MAHSAAAVPLGALEQGCPIRVEHDRRRRQFTVRLNGCHDRAVLLYEYVGK RIVDLQHTEVPDAYRGRGIAKHLAKAALDFVVEEDLKAHLTCWYIQKYVK ENPLPQYLERLQP chromosome location: 21238870-21253410 (17p11.2) Database cross references: | MF: GO:0004402_(0.33)_histone_acetyltransferase activity BP: GO:0006473_(0.68)_protein_acetylation GO:0018393_(0.44)_internal_peptidyl-lysine acetylation GO:0001702_(0.37)_gastrulation_with_mouth_forming second GO:0016573_(0.35)_histone_acetylation GO:0006474_(0.35)_N-terminal_protein_amino_acid acetylation GO:0050794_(0.33)_regulation_of_cellular_process GO:0048523_(0.27)_negative_regulation_of_cellular process GO:0048518_(0.20)_positive_regulation_of biological_process GO:0007162_(0.17)_negative_regulation_of_cell adhesion GO:0050435_(0.14)_beta-amyloid_metabolic_process GO:0043066_(0.14)_negative_regulation_of_apoptotic process GO:0018003_(0.14)_peptidyl-lysine_N6-acetylation GO:0010628_(0.14)_positive_regulation_of_gene expression GO:0006749_(0.10)_glutathione_metabolic_process GO:0051586_(0.06)_positive_regulation_of_dopamine uptake_involved_in_synaptic_transmission CC: GO:0044424_(1.00)_intracellular_part GO:0043227_(0.78)_membrane-bounded_organelle GO:0043231_(0.70)_intracellular_membrane-bounded organelle GO:0043234_(0.64)_protein_complex GO:0031248_(0.55)_protein_acetyltransferase complex GO:0044444_(0.53)_cytoplasmic_part GO:0044446_(0.46)_intracellular_organelle_part GO:0005737_(0.36)_cytoplasm GO:0044428_(0.33)_nuclear_part GO:0044427_(0.33)_chromosomal_part GO:0044425_(0.30)_membrane_part GO:0005634_(0.30)_nucleus GO:0005777_(0.28)_peroxisome GO:0016021_(0.26)_integral_component_of_membrane GO:0044454_(0.22)_nuclear_chromosome_part | UniProt annotation: GO:0005515_protein_binding UniProt annotation score: ◉◉○○○ NextProt annotation: GO:0005515_protein_binding | ||
14 | >NX_A8MSI8-1|LYRM9_HUMAN LYR motif-containing protein 9 GN=LYRM9 MAPLPGAELVRRPLQLYRYLLRCCQQLPTKGIQQHYKHAVRQSFRVHSDE DNPERIQQIIKRAIEDADWIMNKYKKQN chromosome location: 27878314-27894752 (17q11.2) Database cross references: | MF: GO:0003824_(0.63)_catalytic_activity GO:0008137_(0.52)_NADH_dehydrogenase_(ubiquinone) activity GO:0031071_(0.11)_cysteine_desulfurase_activity GO:0051536_(0.06)_iron-sulfur_cluster_binding BP: GO:0009987_(0.71)_cellular_process GO:0044699_(0.50)_single-organism_process GO:0044763_(0.42)_single-organism_cellular_process GO:0022607_(0.41)_cellular_component_assembly GO:0043623_(0.36)_cellular_protein_complex assembly GO:0008152_(0.33)_metabolic_process GO:0070271_(0.32)_protein_complex_biogenesis GO:0033108_(0.32)_mitochondrial_respiratory_chain complex_assembly GO:0050794_(0.31)_regulation_of_cellular_process GO:0050896_(0.29)_response_to_stimulus GO:0044237_(0.28)_cellular_metabolic_process GO:0034553_(0.28)_mitochondrial_respiratory_chain complex_II_assembly GO:0016192_(0.28)_vesicle-mediated_transport GO:0051716_(0.26)_cellular_response_to_stimulus GO:0044710_(0.26)_single-organism_metabolic process CC: GO:0044424_(0.88)_intracellular_part GO:0044444_(0.83)_cytoplasmic_part GO:0043227_(0.82)_membrane-bounded_organelle GO:0043231_(0.75)_intracellular_membrane-bounded organelle GO:0044446_(0.65)_intracellular_organelle_part GO:0005737_(0.56)_cytoplasm GO:0005739_(0.53)_mitochondrion GO:0044421_(0.42)_extracellular_region_part GO:0070062_(0.40)_extracellular_exosome GO:0016020_(0.40)_membrane GO:0005576_(0.40)_extracellular_region GO:0031090_(0.26)_organelle_membrane GO:0005829_(0.26)_cytosol GO:0098805_(0.25)_whole_membrane GO:0098588_(0.25)_bounding_membrane_of_organelle | UniProt annotation score: ◉◉○○○ | ||
15 | >NX_P0DI83-1|NARR_HUMAN Ras-related protein Rab-34, isoform NARR GN=RAB34 MVGQPQPRDDVGSPRPRVIVGTIRPRVIVGTIRPRVIVGSARARPPPDGT PRPQLAAEESPRPRVIFGTPRARVILGSPRPRVIVSSPWPAVVVASPRPR TPVGSPWPRVVVGTPRPRVIVGSPRARVADADPASAPSQGALQGRRQDEH SGTRAEGSRPGGAAPVPEEGGRFARAQRLPPPRHLRLPGAPDRHRGQI chromosome location: 28714281-28718429 (17q11.2) Database cross references: | MF: GO:0003824_(0.33)_catalytic_activity GO:0003700_(0.25)_transcription_factor_activity, sequence-specific_DNA_binding GO:0000981_(0.23)_RNA_polymerase_II_transcription factor_activity,_sequence-specific_DNA_binding GO:1901363_(0.19)_heterocyclic_compound_binding GO:0097159_(0.19)_organic_cyclic_compound_binding GO:0016740_(0.19)_transferase_activity GO:0016787_(0.18)_hydrolase_activity GO:0016772_(0.17)_transferase_activity, transferring_phosphorus-containing_groups GO:0003676_(0.17)_nucleic_acid_binding GO:0003723_(0.14)_RNA_binding GO:0005198_(0.12)_structural_molecule_activity GO:0044877_(0.10)_macromolecular_complex_binding GO:0016779_(0.10)_nucleotidyltransferase_activity GO:0034062_(0.09)_RNA_polymerase_activity GO:0008092_(0.09)_cytoskeletal_protein_binding BP: GO:0009987_(0.59)_cellular_process GO:0065007_(0.56)_biological_regulation GO:0032502_(0.51)_developmental_process GO:0050794_(0.50)_regulation_of_cellular_process GO:0044699_(0.49)_single-organism_process GO:0044763_(0.41)_single-organism_cellular_process GO:0016043_(0.32)_cellular_component_organization GO:0080090_(0.31)_regulation_of_primary_metabolic process GO:0060255_(0.31)_regulation_of_macromolecule metabolic_process GO:0031323_(0.31)_regulation_of_cellular_metabolic process GO:0031326_(0.30)_regulation_of_cellular biosynthetic_process GO:2000112_(0.29)_regulation_of_cellular macromolecule_biosynthetic_process GO:0019219_(0.29)_regulation_of_nucleobase- containing_compound_metabolic_process GO:0006355_(0.28)_regulation_of_transcription, DNA-templated GO:0008152_(0.27)_metabolic_process CC: GO:0044464_(0.88)_cell_part GO:0044424_(0.73)_intracellular_part GO:0044422_(0.50)_organelle_part GO:0044446_(0.48)_intracellular_organelle_part GO:0032991_(0.46)_macromolecular_complex GO:0016020_(0.46)_membrane GO:0044425_(0.44)_membrane_part GO:0043234_(0.43)_protein_complex GO:0043226_(0.42)_organelle GO:0043229_(0.41)_intracellular_organelle GO:0043227_(0.38)_membrane-bounded_organelle GO:0044444_(0.36)_cytoplasmic_part GO:0031224_(0.36)_intrinsic_component_of_membrane GO:0043231_(0.35)_intracellular_membrane-bounded organelle GO:0016021_(0.31)_integral_component_of_membrane | UniProt annotation: GO:0005730_nucleolus GO:0005634_nucleus UniProt annotation score: ◉◉◉◉◉ | High: nerve/ganglion) epithelial_cells) cells) Langerhans;_melanocytes) | |
16 | >NX_Q8WU58-1|F222B_HUMAN FAM222B GN=FAM222B MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAK KVANNPLTIKIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAG LLAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYATVAPSTLAHPQAQ ALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQ PMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPPNVTVSTSTIP LSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISR SLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGIS RVPTGYPSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAG PGFVGKAPAYPQELCLAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYF QPLWNNILPTPNSDSSGSQDLAMPFHGGQPTGAPLDCAAAPGAHYRAGTG GGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRAPGNRAPDPTE SRSLHIQHPGYR chromosome location: 28755978-28855232 (17q11.2) Database cross references: | MF: GO:0003676_(0.52)_nucleic_acid_binding GO:0003824_(0.48)_catalytic_activity GO:0043169_(0.32)_cation_binding GO:0003712_(0.20)_transcription_cofactor_activity GO:0003723_(0.18)_RNA_binding GO:0016787_(0.14)_hydrolase_activity GO:0016740_(0.14)_transferase_activity GO:0003713_(0.14)_transcription_coactivator activity GO:0044822_(0.12)_poly(A)_RNA_binding GO:0003677_(0.10)_DNA_binding GO:0016772_(0.09)_transferase_activity, transferring_phosphorus-containing_groups GO:0008134_(0.07)_transcription_factor_binding GO:0003700_(0.07)_transcription_factor_activity, sequence-specific_DNA_binding GO:0001104_(0.07)_RNA_polymerase_II_transcription cofactor_activity GO:0044877_(0.06)_macromolecular_complex_binding BP: GO:0009987_(0.61)_cellular_process GO:0065007_(0.55)_biological_regulation GO:0050789_(0.52)_regulation_of_biological_process GO:0050794_(0.49)_regulation_of_cellular_process GO:0044699_(0.41)_single-organism_process GO:0019222_(0.33)_regulation_of_metabolic_process GO:0060255_(0.32)_regulation_of_macromolecule metabolic_process GO:0031323_(0.32)_regulation_of_cellular_metabolic process GO:0044763_(0.31)_single-organism_cellular_process GO:0080090_(0.30)_regulation_of_primary_metabolic process GO:0071704_(0.30)_organic_substance_metabolic process GO:0044238_(0.30)_primary_metabolic_process GO:0044237_(0.30)_cellular_metabolic_process GO:0010468_(0.30)_regulation_of_gene_expression GO:0051171_(0.29)_regulation_of_nitrogen_compound metabolic_process CC: GO:0005654_(1.00)_nucleoplasm | UniProt annotation: GO:0005654_nucleoplasm UniProt annotation score: ◉◉○○○ | High: cells) center_cells;_squamous_epithelial_cells) glandular_cells) epithelial_cells) Langerhans) germinal_center_cells) Langerhans;_melanocytes) | |
17 | >NX_A4FU69-1|EFCB5_HUMAN EF-hand calcium-binding domain-containing protein 5 GN=EFCAB5 MNESASQEELRPAQENRKEDKERKWNLTEVKELHETLQSVPDVPVKEDTN SVVEKAMDEIKSQELNLEGQRKISPGSIKDSKTEASGNIAIRKSAKVIFA LDETELKSKPEHTWKKNLFERMEARAQAMQQKIIDKENLKKELEKKAEKK LPRDNLAKEWFNTDSMTLNNTAYLLDKLLPTLVPGVENMLTQVEKKKVLT EADTPSKFDPINYLGEYLIRNNPNYIKDPGMSGYQRLMKEVTEDLKIYVP DTICNRVSKMKENVKQNRKQRESIDKIIVKVANTRKQALQEQFDEWILDP KGMIPKSVIQNVLQEFFQNPDFKLGSHCKQLDITDSTEPRLNKMEFTEYI SSHIKDLKSEMFEELLKHLCHSADEFREVIKADMRRQMFAELFLHCDHGK VGFLDRQRTLALLELFYDHSSQMLRSLLRNPRQWPFIEFEEINLTELWGD MDNQKHIYEGFDKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTST PSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHT ESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSR ESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQK SEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEK RSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQK IEGKSWSGEFFTCNWKMKYVTFEDEEQANLIYGNSRFTDLHSIIRNIQSC KEVKGRTAFNGVSFNLLQFVQLLETFVGEDAPLSVSETLTSFFKEGYVET EQEKMNALEQFSQNAFQVRQRLLLEAIFQKWDSDGSGFLDLKEVDELLYT YKEGMEKESMKKAKLHIQFPKPHPGHEVRLSSKQFQNYIELVVSELRGNE DQVLESVVEFLMNALERSHIESLRNSARRKWLHQIQCAAETSGVSLEPVY SETFKALMQDAEAHGNKKISAHISLLEENLLLPEKGNVLLRNVACTLDDA QFVLNRVLYRDMKGISFTVVDEGKPIHVPQVQYHGNIFFWNQSRNKHDYN GSFLALPLQDAYMRIFGVLAVDTLRDPHEINIFLPHEIRFYQGVANVFST AYHYVHSREHILHIVITGIGWLYDVTSSITSITTYFVEPSPAQDSDYVLR NMMVTGQLGLTEIHKNPPTIHRKSCIFRDFLFKCTDSSEVVLASACGETH IVVPLRERTGEALGVLDFNIGQNRMLLCQEYKDLQKMMKVVQVACYEILG EFSGEIKKKYILEIENVREVQRAGILFFRIMLLELQESIQLLNSMEFVSL LLYDHTLVTEPNSPQDSKSMELEANVKLVRDILKAVILFFHPELEFSSDF GSWDKCKFYVNKYLVNNICAFDPTAKHVEVNVQLIDEYIRDHSRTEVWKF GNVVIEHLYHWIHICSALMKITKQLNSGITPPLPSKTDNYMYAKMPGEGL QEK chromosome location: 29929200-30108452 (17q11.2) Database cross references: | MF: GO:0003824_(0.32)_catalytic_activity GO:0005198_(0.19)_structural_molecule_activity GO:1901363_(0.17)_heterocyclic_compound_binding GO:0097159_(0.17)_organic_cyclic_compound_binding GO:0016787_(0.16)_hydrolase_activity GO:0016740_(0.16)_transferase_activity GO:0008092_(0.16)_cytoskeletal_protein_binding GO:0005102_(0.14)_receptor_binding GO:0003676_(0.14)_nucleic_acid_binding GO:0016887_(0.13)_ATPase_activity GO:0046789_(0.10)_host_cell_surface_receptor binding GO:0044877_(0.10)_macromolecular_complex_binding GO:0004674_(0.10)_protein_serine/threonine_kinase activity GO:0032403_(0.09)_protein_complex_binding GO:0003774_(0.09)_motor_activity BP: GO:0009987_(0.71)_cellular_process GO:0044699_(0.66)_single-organism_process GO:0044763_(0.50)_single-organism_cellular_process GO:0016043_(0.40)_cellular_component_organization GO:0065007_(0.38)_biological_regulation GO:0032502_(0.32)_developmental_process GO:0050789_(0.31)_regulation_of_biological_process GO:0044767_(0.31)_single-organism_developmental process GO:0050794_(0.30)_regulation_of_cellular_process GO:0048856_(0.23)_anatomical_structure_development GO:0008152_(0.23)_metabolic_process GO:0006996_(0.23)_organelle_organization GO:1902589_(0.21)_single-organism_organelle organization GO:0007010_(0.21)_cytoskeleton_organization GO:0071704_(0.20)_organic_substance_metabolic process CC: GO:0044464_(0.81)_cell_part GO:0044424_(0.74)_intracellular_part GO:0044422_(0.46)_organelle_part GO:0043226_(0.42)_organelle GO:0044446_(0.41)_intracellular_organelle_part GO:0043229_(0.40)_intracellular_organelle GO:0043227_(0.34)_membrane-bounded_organelle GO:0043231_(0.29)_intracellular_membrane-bounded organelle GO:0044430_(0.26)_cytoskeletal_part GO:0032991_(0.26)_macromolecular_complex GO:0044444_(0.25)_cytoplasmic_part GO:0043234_(0.24)_protein_complex GO:0005634_(0.22)_nucleus GO:0005737_(0.21)_cytoplasm GO:0043232_(0.17)_intracellular_non-membrane- bounded_organelle | UniProt annotation: GO:0005509_calcium_ion_binding GO:0046872_metal_ion_binding UniProt annotation score: ◉◉◉○○ NextProt annotation: GO:0005509_calcium_ion_binding | ||
18 | >NX_P34910-1|EVI2B_HUMAN EVI2B GN=EVI2B MDPKYFILILFCGHLNNTFFSKTETITTEKQSQPTLFTSSMSQVLANSQN TTGNPLGQPTQFSDTFSGQSISPAKVTAGQPTPAVYTSSEKPEAHTSAGQ PLAYNTKQPTPIANTSSQQAVFTSARQLPSARTSTTQPPKSFVYTFTQQS SSVQIPSRKQITVHNPSTQPTSTVKNSPRSTPGFILDTTSNKQTPQKNNY NSIAAILIGVLLTSMLVAIIIIVLWKCLRKPVLNDQNWAGRSPFADGETP DICMDNIRENEISTKRTSIISLTPWKPSKSTLLADDLEIKLFESSENIED SNNPKTEKIKDQVNGTSEDSADGSTVGTAVSSSDDADLPPPPPLLDLEGQ ESNQSDKPTMTIVSPLPNDSTSLPPSLDCLNQDCGDHKSEIIQSFPPLDS LNLPLPPVDFMKNQEDSNLEIQCQEFSIPPNSDQDLNESLPPPPAELL chromosome location: 31303766-31314112 (17q11.2) Database cross references: | MF: GO:0005198_(0.37)_structural_molecule_activity GO:0003824_(0.30)_catalytic_activity GO:0016740_(0.17)_transferase_activity GO:1901363_(0.13)_heterocyclic_compound_binding GO:0097159_(0.13)_organic_cyclic_compound_binding GO:0016787_(0.12)_hydrolase_activity GO:0016772_(0.11)_transferase_activity, transferring_phosphorus-containing_groups GO:0003676_(0.11)_nucleic_acid_binding GO:0008092_(0.09)_cytoskeletal_protein_binding GO:0005215_(0.08)_transporter_activity GO:0016773_(0.06)_phosphotransferase_activity, alcohol_group_as_acceptor GO:0016301_(0.06)_kinase_activity GO:0008190_(0.06)_eukaryotic_initiation_factor_4E binding GO:0005201_(0.06)_extracellular_matrix_structural constituent GO:0003779_(0.06)_actin_binding BP: GO:0009987_(0.62)_cellular_process GO:0044699_(0.48)_single-organism_process GO:0065007_(0.45)_biological_regulation GO:0051179_(0.43)_localization GO:0051234_(0.42)_establishment_of_localization GO:0006810_(0.41)_transport GO:0051649_(0.39)_establishment_of_localization_in cell GO:0051641_(0.39)_cellular_localization GO:0050789_(0.39)_regulation_of_biological_process GO:0050794_(0.37)_regulation_of_cellular_process GO:0046907_(0.37)_intracellular_transport GO:0044763_(0.36)_single-organism_cellular_process GO:0071702_(0.34)_organic_substance_transport GO:0051169_(0.33)_nuclear_transport GO:0050658_(0.32)_RNA_transport CC: GO:0005887_(1.00)_integral_component_of_plasma membrane | UniProt annotation: Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells. {ECO:0000269|PubMed:28186500}. GO:2000035_regulation_of_stem_cell_division GO:0030854_positive_regulation_of_granulocyte differentiation GO:0061515_myeloid_cell_development GO:0005887_integral_component_of_plasma_membrane GO:0043066_negative_regulation_of_apoptotic process GO:0071157_negative_regulation_of_cell_cycle arrest GO:0045660_positive_regulation_of_neutrophil differentiation GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉◉◉ NextProt annotation: Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells. GO:0030854_positive_regulation_of_granulocyte differentiation GO:0043066_negative_regulation_of_apoptotic process GO:0045660_positive_regulation_of_neutrophil differentiation GO:0061515_myeloid_cell_development GO:0071157_negative_regulation_of_cell_cycle arrest GO:2000035_regulation_of_stem_cell_division | High: cells) germinal_center_cells) pulp) center_cells) | |
19 | >NX_Q96QE4-1|LR37B_HUMAN Leucine-rich repeat-containing protein 37B GN=LRRC37B MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSS RSSHLPWESPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKE LDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLP RLKWVQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERW SLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPG PPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEV TMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPP SDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPG LAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQD SLVQSETAPEEQKASTSTNICELCTCGDETLSCVGLSPKQRLRQVPVPEP DTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFE GLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAW HGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILT MTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEE ASVGNPEGAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLEI QLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLM KLLSEQQEAKALNVEWDTDQQKTNYINENMEQNEQKEQKSSELMKEVPGD DYKNKLIFAISVTVILIILIIIFCLIEVNSHKRASEKYKDNPSISGA chromosome location: 32007872-32053504 (17q11.2) Database cross references: | MF: GO:0005215_(0.35)_transporter_activity GO:0022892_(0.34)_substrate-specific_transporter activity GO:0098772_(0.28)_molecular_function_regulator GO:0004857_(0.27)_enzyme_inhibitor_activity GO:0004860_(0.26)_protein_kinase_inhibitor activity GO:0005102_(0.16)_receptor_binding GO:0097367_(0.15)_carbohydrate_derivative_binding GO:0004872_(0.15)_receptor_activity GO:0005539_(0.14)_glycosaminoglycan_binding GO:0008201_(0.13)_heparin_binding GO:0048495_(0.12)_Roundabout_binding GO:0004871_(0.12)_signal_transducer_activity GO:0003824_(0.12)_catalytic_activity GO:1901363_(0.11)_heterocyclic_compound_binding GO:0097159_(0.11)_organic_cyclic_compound_binding BP: GO:0065007_(0.62)_biological_regulation GO:0050789_(0.61)_regulation_of_biological_process GO:0009987_(0.60)_cellular_process GO:0050794_(0.59)_regulation_of_cellular_process GO:0044699_(0.53)_single-organism_process GO:0044763_(0.48)_single-organism_cellular_process GO:0007165_(0.45)_signal_transduction GO:0032502_(0.42)_developmental_process GO:0044767_(0.41)_single-organism_developmental process GO:0051179_(0.35)_localization GO:0016043_(0.35)_cellular_component_organization GO:0051641_(0.34)_cellular_localization GO:0006810_(0.34)_transport GO:0051649_(0.33)_establishment_of_localization_in cell GO:0008104_(0.33)_protein_localization CC: GO:0044464_(0.72)_cell_part GO:0044424_(0.53)_intracellular_part GO:0005737_(0.49)_cytoplasm GO:0044421_(0.30)_extracellular_region_part GO:0005615_(0.25)_extracellular_space GO:0005578_(0.23)_proteinaceous_extracellular matrix GO:0044425_(0.17)_membrane_part GO:0031224_(0.15)_intrinsic_component_of_membrane GO:0044459_(0.14)_plasma_membrane_part GO:0016021_(0.14)_integral_component_of_membrane GO:0031226_(0.13)_intrinsic_component_of_plasma membrane GO:0005887_(0.12)_integral_component_of_plasma membrane GO:0016020_(0.11)_membrane GO:0005886_(0.09)_plasma_membrane GO:0043227_(0.06)_membrane-bounded_organelle | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ | Medium: | |
20 | >NX_Q9Y2Y6-1|TMM98_HUMAN Transmembrane protein 98 GN=TMEM98 METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLI GAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKI CHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPL DPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVL REAALASEPDKGLPGPEGFLQEQSAI chromosome location: 32927910-32945106 (17q11.2) Database cross references: | MF: GO:0046914_(0.50)_transition_metal_ion_binding GO:0046906_(0.50)_tetrapyrrole_binding GO:0016676_(0.50)_oxidoreductase_activity,_acting on_a_heme_group_of_donors,_oxygen_as_acceptor GO:0015078_(0.50)_hydrogen_ion_transmembrane transporter_activity GO:0015002_(0.50)_heme-copper_terminal_oxidase activity GO:0009055_(0.50)_electron_carrier_activity BP: GO:0098662_(0.50)_inorganic_cation_transmembrane transport GO:0046034_(0.50)_ATP_metabolic_process GO:0045333_(0.50)_cellular_respiration GO:0016310_(0.50)_phosphorylation GO:0015672_(0.50)_monovalent_inorganic_cation transport GO:0006818_(0.50)_hydrogen_transport GO:0050794_(0.35)_regulation_of_cellular_process CC: GO:0043231_(1.00)_intracellular_membrane-bounded organelle GO:0005634_(0.52)_nucleus GO:0005783_(0.48)_endoplasmic_reticulum GO:0005654_(0.07)_nucleoplasm GO:0005737_(0.04)_cytoplasm | UniProt annotation: GO:0005783_endoplasmic_reticulum GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ | ||
21 | >NX_Q8TC99-1|FNDC8_HUMAN Fibronectin type III domain-containing protein 8 GN=FNDC8 MASEALHQVGDGEEAVLKKENFNMMNALDQLPKPFSNPKSMNRTVTTKGL PLASKGNLVNFLEDDTINLLKPLPVEDSDCSSDETSISAFSSTLLNPIKL AVTQPNSSFFAGMLEGELNKLSFSPMAKNAENEDLALGPCPCPSKSQMAT RGLLDLDNPELETETSSTHSESSVVVDLPDTPFIFEHTVNNSTAVISWTY ALGKQPVSFYQLLLQEVAKTQENELPEAKNRPWIFNKILGTTVKLMELKP NTCYCLSVRAANTAGVGKWCKPYKFATLATDFSSFPENYPIQITVRRKEP RQKIVSIGPEEMRRLEDLEYLFPC chromosome location: 35121579-35130732 (17q12) Database cross references: | MF: GO:0003824_(0.61)_catalytic_activity GO:0097367_(0.51)_carbohydrate_derivative_binding GO:1901363_(0.50)_heterocyclic_compound_binding GO:0097159_(0.50)_organic_cyclic_compound_binding GO:0035639_(0.49)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.49)_adenyl_ribonucleotide_binding GO:0032550_(0.49)_purine_ribonucleoside_binding GO:0016740_(0.37)_transferase_activity GO:0004872_(0.37)_receptor_activity GO:0016787_(0.35)_hydrolase_activity GO:0004888_(0.35)_transmembrane_signaling_receptor activity GO:0004672_(0.35)_protein_kinase_activity GO:0008186_(0.31)_RNA-dependent_ATPase_activity GO:0008026_(0.31)_ATP-dependent_helicase_activity GO:0003724_(0.31)_RNA_helicase_activity BP: GO:0044699_(0.83)_single-organism_process GO:0009987_(0.83)_cellular_process GO:0044763_(0.77)_single-organism_cellular_process GO:0065007_(0.72)_biological_regulation GO:0050789_(0.72)_regulation_of_biological_process GO:0050794_(0.69)_regulation_of_cellular_process GO:0032502_(0.67)_developmental_process GO:0044767_(0.63)_single-organism_developmental process GO:0048856_(0.54)_anatomical_structure_development GO:0048869_(0.52)_cellular_developmental_process GO:0071704_(0.41)_organic_substance_metabolic process GO:0044238_(0.40)_primary_metabolic_process GO:0044237_(0.40)_cellular_metabolic_process GO:0043170_(0.40)_macromolecule_metabolic_process GO:0006928_(0.40)_movement_of_cell_or_subcellular component CC: GO:0044464_(1.00)_cell_part GO:0005634_(0.96)_nucleus GO:0005887_(0.04)_integral_component_of_plasma membrane | UniProt annotation: GO:0005634_nucleus UniProt annotation score: ◉◉○○○ | High: preleptotene_spermatocytes;_sertoli_cells; spermatogonia) | |
22 | >NX_Q8WW18-1|CQ050_HUMAN Uncharacterized protein C17orf50 GN=C17orf50 MDKHGVKTPLWKKETEELRAEDAEQEEGKEGSEDEDEDNQRPLEDSATEG EEPPRVAEEGEGRERRSVSYCPLRQESSTQQVALLRRADSGFWGWLGPLA LLGGLTAPTDRKRSLPEEPCVLEIRRRPPRRGGCACCELLFCKKCRSLHS HPAYVAHCVLDHPDLGKAGAAGNS chromosome location: 35760897-35765079 (17q12) Database cross references: | MF: GO:0046982_(0.12)_protein_heterodimerization activity GO:0008601_(0.12)_protein_phosphatase_type_2A regulator_activity GO:0004722_(0.12)_protein_serine/threonine phosphatase_activity GO:0003823_(0.12)_antigen_binding BP: GO:2001241_(0.12)_positive_regulation_of_extrinsic apoptotic_signaling_pathway_in_absence_of_ligand GO:1903538_(0.12)_regulation_of_meiotic_cell_cycle process_involved_in_oocyte_maturation GO:0070262_(0.12)_peptidyl-serine dephosphorylation GO:0051754_(0.12)_meiotic_sister_chromatid cohesion,_centromeric GO:0051306_(0.12)_mitotic_sister_chromatid separation GO:0051232_(0.12)_meiotic_spindle_elongation GO:0042518_(0.12)_negative_regulation_of_tyrosine phosphorylation_of_Stat3_protein GO:0034047_(0.12)_regulation_of_protein phosphatase_type_2A_activity GO:0030308_(0.12)_negative_regulation_of_cell growth GO:0030155_(0.12)_regulation_of_cell_adhesion GO:0030111_(0.12)_regulation_of_Wnt_signaling pathway GO:0019932_(0.12)_second-messenger-mediated signaling GO:0010033_(0.12)_response_to_organic_substance GO:0008380_(0.12)_RNA_splicing GO:0007143_(0.12)_female_meiotic_division CC: GO:0044446_(1.00)_intracellular_organelle_part GO:0005737_(1.00)_cytoplasm GO:0043657_(0.90)_host_cell GO:0070062_(0.77)_extracellular_exosome GO:0016020_(0.77)_membrane GO:0005829_(0.77)_cytosol GO:0005634_(0.77)_nucleus GO:0044428_(0.56)_nuclear_part GO:0072372_(0.37)_primary_cilium GO:0034399_(0.37)_nuclear_periphery GO:0031965_(0.37)_nuclear_membrane GO:0015630_(0.37)_microtubule_cytoskeleton GO:0005739_(0.37)_mitochondrion GO:0005694_(0.37)_chromosome GO:0000775_(0.37)_chromosome,_centromeric_region | UniProt annotation score: ◉○○○○ | ||
23 | >NX_A8MV24-1|CQ098_HUMAN Uncharacterized protein C17orf98 GN=C17orf98 MAYLSECRLRLEKGFILDGVAVSTAARAYGRSRPKLWSAIPPYNAQQDYH ARSYFQSHVVPPLLRKTDQDHGGTGRDGWIVDYIHIFGQGQRYLNRRNWA GTGHSLQQVTGHDHYNADLKPIDGFNGRFGYRRNTPALRQSTSVFGEVTH FPLF chromosome location: 38835088-38841455 (17q12) Database cross references: | MF: GO:0015926_(0.48)_glucosidase_activity BP: GO:0051275_(0.37)_beta-glucan_catabolic_process GO:0030243_(0.37)_cellulose_metabolic_process CC: GO:0005576_(0.75)_extracellular_region GO:0009507_(0.25)_chloroplast | UniProt annotation score: ◉○○○○ | ||
24 | >NX_Q9BQS6-1|HSPB9_HUMAN Heat shock protein beta-9 GN=HSPB9 MQRVGNTFSNESRVASRCPSVGLAERNRVATMPVRLLRDSPAAQEDNDHA RDGFQMKLDAHGFAPEELVVQVDGQWLMVTGQQQLDVRDPERVSYRMSQK VHRKMLPSNLSPTAMTCCLTPSGQLWVRGQCVALALPEAQTGPSPRLGSL GSKASNLTR chromosome location: 42121431-42123352 (17q21.2) Database cross references: | MF: GO:0042802_(0.76)_identical_protein_binding GO:0042803_(0.63)_protein_homodimerization activity GO:0051082_(0.52)_unfolded_protein_binding GO:0005212_(0.50)_structural_constituent_of_eye lens GO:0032182_(0.39)_ubiquitin-like_protein_binding GO:0030291_(0.39)_protein_serine/threonine_kinase inhibitor_activity GO:0019900_(0.39)_kinase_binding GO:0003723_(0.37)_RNA_binding GO:0043169_(0.35)_cation_binding GO:0043130_(0.07)_ubiquitin_binding GO:0008426_(0.07)_protein_kinase_C_inhibitor activity GO:0005080_(0.07)_protein_kinase_C_binding GO:0044822_(0.05)_poly(A)_RNA_binding GO:0008017_(0.03)_microtubule_binding GO:0008022_(0.02)_protein_C-terminus_binding BP: GO:0050896_(0.82)_response_to_stimulus GO:0006950_(0.80)_response_to_stress GO:0009987_(0.75)_cellular_process GO:0009628_(0.71)_response_to_abiotic_stimulus GO:0065007_(0.63)_biological_regulation GO:0050789_(0.63)_regulation_of_biological_process GO:0044699_(0.63)_single-organism_process GO:0042221_(0.60)_response_to_chemical GO:0009408_(0.60)_response_to_heat GO:0050794_(0.58)_regulation_of_cellular_process GO:0016043_(0.56)_cellular_component_organization GO:0044763_(0.53)_single-organism_cellular_process GO:0044767_(0.52)_single-organism_developmental process GO:0048523_(0.51)_negative_regulation_of_cellular process GO:0042981_(0.51)_regulation_of_apoptotic_process CC: GO:0044424_(1.00)_intracellular_part GO:0005634_(0.97)_nucleus GO:0005737_(0.96)_cytoplasm GO:0044422_(0.10)_organelle_part GO:0044444_(0.09)_cytoplasmic_part GO:0070062_(0.08)_extracellular_exosome GO:0044449_(0.07)_contractile_fiber_part GO:0043232_(0.07)_intracellular_non-membrane- bounded_organelle GO:0044446_(0.06)_intracellular_organelle_part GO:0043292_(0.06)_contractile_fiber GO:0016020_(0.06)_membrane GO:0030018_(0.05)_Z_disc GO:0005829_(0.05)_cytosol GO:0005886_(0.04)_plasma_membrane GO:0005654_(0.04)_nucleoplasm | UniProt annotation: GO:0005737_cytoplasm GO:0005634_nucleus GO:0005515_protein_binding UniProt annotation score: ◉◉◉○○ NextProt annotation: GO:0005515_protein_binding | ||
25 | >NX_Q96A25-1|T106A_HUMAN Transmembrane protein 106A GN=TMEM106A MGKTFSQLGSWREDENKSILSSKPAIGSKAVNYSSTGSSKSFCSCVPCEG TADASFVTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAV LICLVTSSFIVFFLFPRSVIVQPAGLNSSTVAFDEADIYLNITNILNISN GNYYPIMVTQLTLEVLHLSLVVGQVSNNLLLHIGPLASEQMFYAVATKIR DENTYKICTWLEIKVHHVLLHIQGTLTCSYLSHSEQLVFQSYEYVDCRGN ASVPHQLTPHPP chromosome location: 43211835-43220041 (17q21.31) Database cross references: | MF: GO:0008236_(0.36)_serine-type_peptidase_activity GO:0004175_(0.36)_endopeptidase_activity BP: GO:0048813_(1.00)_dendrite_morphogenesis GO:0032418_(1.00)_lysosome_localization GO:0007041_(0.93)_lysosomal_transport GO:0007040_(0.93)_lysosome_organization GO:0019538_(0.22)_protein_metabolic_process GO:1900006_(0.07)_positive_regulation_of_dendrite development CC: GO:0016020_(0.97)_membrane GO:0044424_(0.28)_intracellular_part GO:0005765_(0.26)_lysosomal_membrane GO:0043227_(0.13)_membrane-bounded_organelle GO:0070062_(0.11)_extracellular_exosome GO:0043231_(0.06)_intracellular_membrane-bounded organelle GO:0005764_(0.02)_lysosome | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ | ||
26 | >NX_B2RV13-1|CF97D_HUMAN Uncharacterized protein C17orf105 GN=C17orf105 MNNSLDYLAYPVIVSNHRQSTTFRKKLDFGHYVSHKNRIQIAKPTVDTKP PVAHTNHILKLSKLQGEQKKINKIEYENKQLCQKIANAHRGPAKVDCWNE YFSKSLNRETRNRELVRITMENQGILKRLVDRKPHYDRRASEIDWQNSRR YIRNTTRYLLSQNE chromosome location: 43780435-43787612 (17q21.31) Database cross references: | MF: GO:0003824_(0.95)_catalytic_activity GO:0016740_(0.44)_transferase_activity GO:0004842_(0.41)_ubiquitin-protein_transferase activity GO:0004185_(0.36)_serine-type_carboxypeptidase activity GO:0004181_(0.36)_metallocarboxypeptidase_activity GO:0003755_(0.19)_peptidyl-prolyl_cis-trans isomerase_activity GO:0043565_(0.09)_sequence-specific_DNA_binding GO:0030412_(0.09)_formimidoyltetrahydrofolate cyclodeaminase_activity GO:0003690_(0.09)_double-stranded_DNA_binding GO:0030409_(0.05)_glutamate_formimidoyltransferase activity GO:0019903_(0.05)_protein_phosphatase_binding GO:0019215_(0.05)_intermediate_filament_binding GO:0008017_(0.05)_microtubule_binding GO:0005542_(0.05)_folic_acid_binding GO:0005102_(0.05)_receptor_binding BP: GO:0044238_(1.00)_primary_metabolic_process GO:0044237_(1.00)_cellular_metabolic_process GO:0043170_(1.00)_macromolecule_metabolic_process GO:0019538_(0.94)_protein_metabolic_process GO:0044260_(0.58)_cellular_macromolecule_metabolic process GO:0034641_(0.53)_cellular_nitrogen_compound metabolic_process GO:0006464_(0.51)_cellular_protein_modification process GO:0042787_(0.49)_protein_ubiquitination_involved in_ubiquitin-dependent_protein_catabolic_process GO:1901564_(0.47)_organonitrogen_compound metabolic_process GO:0043603_(0.47)_cellular_amide_metabolic_process GO:0016485_(0.44)_protein_processing GO:0006518_(0.44)_peptide_metabolic_process GO:1901360_(0.10)_organic_cyclic_compound metabolic_process GO:0046483_(0.10)_heterocycle_metabolic_process GO:0042592_(0.10)_homeostatic_process CC: GO:0044464_(1.00)_cell_part GO:0044424_(0.90)_intracellular_part GO:0043231_(0.88)_intracellular_membrane-bounded organelle GO:0005737_(0.88)_cytoplasm GO:0005634_(0.81)_nucleus GO:0005829_(0.76)_cytosol GO:0044446_(0.65)_intracellular_organelle_part GO:0044428_(0.54)_nuclear_part GO:0016020_(0.51)_membrane GO:0005654_(0.51)_nucleoplasm GO:0044421_(0.48)_extracellular_region_part GO:0044454_(0.45)_nuclear_chromosome_part GO:0032991_(0.45)_macromolecular_complex GO:0005615_(0.44)_extracellular_space GO:0000790_(0.41)_nuclear_chromatin | UniProt annotation score: ◉◉○○○ | High: | |
27 | >NX_Q3MHD2-1|LSM12_HUMAN Protein LSM12 homolog GN=LSM12 MAAPPGEYFSVGSQVSCRTCQEQRLQGEVVAFDYQSKMLALKCPSSSGKP NHADILLINLQYVSEVEIINDRTETPPPLASLNVSKLASKARTEKEEKLS QAYAISAGVSLEGQQLFQTIHKTIKDCKWQEKNIVVMEEVVITPPYQVEN CKGKEGSALSHVRKIVEKHFRDVESQKILQRSQAQQPQKEAALSS chromosome location: 44034635-44067619 (17q21.31) Database cross references: | MF: GO:0003723_(0.59)_RNA_binding GO:0003729_(0.13)_mRNA_binding GO:0046872_(0.11)_metal_ion_binding GO:0008810_(0.06)_cellulase_activity BP: GO:0009987_(1.00)_cellular_process GO:0044238_(0.80)_primary_metabolic_process GO:0044237_(0.80)_cellular_metabolic_process GO:0043170_(0.80)_macromolecule_metabolic_process GO:0090304_(0.79)_nucleic_acid_metabolic_process GO:0044260_(0.74)_cellular_macromolecule_metabolic process GO:0016070_(0.73)_RNA_metabolic_process GO:0022618_(0.39)_ribonucleoprotein_complex assembly GO:0000387_(0.32)_spliceosomal_snRNP_assembly GO:0051170_(0.11)_nuclear_import GO:0000398_(0.11)_mRNA_splicing,_via_spliceosome GO:0033962_(0.07)_cytoplasmic_mRNA_processing_body assembly GO:0031087_(0.07)_deadenylation-independent decapping_of_nuclear-transcribed_mRNA GO:0030245_(0.05)_cellulose_catabolic_process CC: GO:0044424_(1.00)_intracellular_part GO:0044444_(0.75)_cytoplasmic_part GO:0043229_(0.64)_intracellular_organelle GO:0032991_(0.60)_macromolecular_complex GO:0005576_(0.55)_extracellular_region GO:0005829_(0.47)_cytosol GO:0005634_(0.33)_nucleus GO:0036464_(0.31)_cytoplasmic_ribonucleoprotein granule GO:0034719_(0.29)_SMN-Sm_protein_complex GO:0032797_(0.29)_SMN_complex GO:0044422_(0.26)_organelle_part GO:0005737_(0.26)_cytoplasm GO:0010494_(0.25)_cytoplasmic_stress_granule GO:0005840_(0.25)_ribosome GO:0016604_(0.19)_nuclear_body | UniProt annotation score: ◉◉◉○○ | High: peripheral_nerve/ganglion) center_cells;_squamous_epithelial_cells) germinal_center_cells) cells) Langerhans;_melanocytes) Langerhans) | |
28 | >NX_Q8N3J3-1|CQ053_HUMAN Uncharacterized protein C17orf53 GN=C17orf53 MACSLQKLFAVEEEFEDEDFLSAVEDAENRFTGSLPVNAGRLRPVSSRPQ ETVQAQSSRLLLLHPTAPSEALGLPDLDLCLPASSTPSADSRPSCIGAAP LRPVSTSSSWIGNQRRVTVTEVLRETARPQSSALHPLLTFESQQQQVGGF EGPEQDEFDKVLASMELEEPGMELECGVSSEAIPILPAQQREGSVLAKKA RVVDLSGSCQKGPVPAIHKAGIMSAQDESLDPVIQCRTPRPPLRPGAVGH LPVPTALTVPTQQLHWEVCPQRSPVQALQPLQAARGTIQSSPQNRFPCQP FQSPSSWLSGKAHLPRPRTPNSSCSTPSRTSSGLFPRIPLQPQAPVSSIG SPVGTPKGPQGALQTPIVTNHLVQLVTAASRTPQQPTHPSTRAKTRRFPG PAGILPHQQSGRSLEDIMVSAPQTPTHGALAKFQTEIVASSQASVEEDFG RGPWLTMKSTLGLDERDPSCFLCTYSIVMVLRKQAALKQLPRNKVPNMAV MIKSLTRSTMDASVVFKDPTGEMQGTVHRLLLETCQNELKPGSVLLLKQI GVFSPSLRNHYLNVTPNNLVHIYSPDSGDGSFLKPSQPFPKDSGSFQHDV AAKPEEGFRTAQNLEAEASPEEELPEADDLDGLLSELPEDFFCGTSS chromosome location: 44141906-44162476 (17q21.31) Database cross references: | MF: GO:0003824_(0.54)_catalytic_activity GO:0016787_(0.43)_hydrolase_activity GO:0004175_(0.37)_endopeptidase_activity GO:0004252_(0.36)_serine-type_endopeptidase activity GO:1901363_(0.18)_heterocyclic_compound_binding GO:0097159_(0.18)_organic_cyclic_compound_binding GO:0016740_(0.17)_transferase_activity GO:0003676_(0.16)_nucleic_acid_binding GO:0016772_(0.12)_transferase_activity, transferring_phosphorus-containing_groups GO:0005215_(0.11)_transporter_activity GO:0015075_(0.09)_ion_transmembrane_transporter activity GO:0004672_(0.09)_protein_kinase_activity GO:0003723_(0.09)_RNA_binding GO:0019899_(0.08)_enzyme_binding GO:0005261_(0.08)_cation_channel_activity BP: GO:0009987_(0.80)_cellular_process GO:0065007_(0.75)_biological_regulation GO:0050789_(0.72)_regulation_of_biological_process GO:0044699_(0.71)_single-organism_process GO:0050794_(0.70)_regulation_of_cellular_process GO:0044763_(0.67)_single-organism_cellular_process GO:0071704_(0.62)_organic_substance_metabolic process GO:0044237_(0.62)_cellular_metabolic_process GO:0016043_(0.62)_cellular_component_organization GO:0044260_(0.61)_cellular_macromolecule_metabolic process GO:0048518_(0.60)_positive_regulation_of biological_process GO:0051179_(0.58)_localization GO:0048519_(0.58)_negative_regulation_of biological_process GO:0065008_(0.57)_regulation_of_biological_quality GO:0048523_(0.57)_negative_regulation_of_cellular process CC: GO:0005576_(0.91)_extracellular_region GO:0044464_(0.90)_cell_part GO:0044424_(0.77)_intracellular_part GO:0044421_(0.70)_extracellular_region_part GO:0043226_(0.70)_organelle GO:0005615_(0.67)_extracellular_space GO:0043227_(0.66)_membrane-bounded_organelle GO:0031982_(0.55)_vesicle GO:0031988_(0.54)_membrane-bounded_vesicle GO:0070062_(0.53)_extracellular_exosome GO:0016020_(0.53)_membrane GO:0044422_(0.48)_organelle_part GO:0044446_(0.47)_intracellular_organelle_part GO:0044444_(0.42)_cytoplasmic_part GO:0043229_(0.39)_intracellular_organelle | UniProt annotation score: ◉◉○○○ | ||
29 | >NX_Q71RG4-1|TMUB2_HUMAN Transmembrane and ubiquitin-like domain-containing protein 2 GN=TMUB2 MISRHLQNNLMSVDPASSQAMELSDVTLIEGVGNEVMVVAGVVVLILALV LAWLSTYVADSGSNQLLGAIVSAGDTSVLHLGHVDHLVAGQGNPEPTELP HPSEGNDEKAEEAGEGRGDSTGEAGAGGGVEPSLEHLLDIQGLPKRQAGA GSSSPEAPLRSEDSTCLPPSPGLITVRLKFLNDTEELAVARPEDTVGALK SKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHCHRSPPGSAVP GPSASLAPSATEPPSLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPA TVSLVGVTVFFSFLVFGMYGR chromosome location: 44186970-44191731 (17q21.31) Database cross references: | MF: GO:1990841_(0.41)_promoter-specific_chromatin binding GO:0051718_(0.41)_DNA (cytosine-5-)-methyltransferase_activity,_acting on_CpG_substrates GO:0045322_(0.41)_unmethylated_CpG_binding GO:0042826_(0.41)_histone_deacetylase_binding GO:0030331_(0.41)_estrogen_receptor_binding GO:0019904_(0.41)_protein_domain_specific_binding GO:0008327_(0.41)_methyl-CpG_binding GO:0008270_(0.41)_zinc_ion_binding GO:0003723_(0.41)_RNA_binding GO:0003690_(0.41)_double-stranded_DNA_binding BP: GO:0009987_(0.92)_cellular_process GO:0044260_(0.90)_cellular_macromolecule_metabolic process GO:0044238_(0.90)_primary_metabolic_process GO:0019538_(0.78)_protein_metabolic_process GO:0019941_(0.63)_modification-dependent_protein catabolic_process GO:0006511_(0.62)_ubiquitin-dependent_protein catabolic_process GO:0065007_(0.57)_biological_regulation GO:0043412_(0.56)_macromolecule_modification GO:0050789_(0.55)_regulation_of_biological_process GO:0071840_(0.54)_cellular_component_organization or_biogenesis GO:0050794_(0.54)_regulation_of_cellular_process GO:0016043_(0.53)_cellular_component_organization GO:0048519_(0.49)_negative_regulation_of biological_process GO:0080090_(0.48)_regulation_of_primary_metabolic process GO:0060255_(0.48)_regulation_of_macromolecule metabolic_process CC: GO:0005634_(1.00)_nucleus GO:0044446_(0.91)_intracellular_organelle_part GO:0044428_(0.89)_nuclear_part GO:0005737_(0.81)_cytoplasm GO:0005654_(0.79)_nucleoplasm GO:0032991_(0.67)_macromolecular_complex GO:0043234_(0.64)_protein_complex GO:0044427_(0.44)_chromosomal_part GO:0043025_(0.44)_neuronal_cell_body GO:0005721_(0.43)_pericentric_heterochromatin GO:0005657_(0.43)_replication_fork GO:0044444_(0.39)_cytoplasmic_part GO:0005829_(0.27)_cytosol GO:0044445_(0.13)_cytosolic_part GO:0016020_(0.11)_membrane | UniProt annotation: GO:0005515_protein_binding GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ NextProt annotation: GO:0005515_protein_binding | High: peripheral_nerve/ganglion) cells) center_cells;_squamous_epithelial_cells) neuropil) germinal_center_cells) cells) pulp) | |
30 | >NX_A8MVW0-1|F1712_HUMAN FAM171A2 GN=FAM171A2 MPPASGPSVLARLLPLLGLLLGSASRAPGKSPPEPPSPQEILIKVQVYVS GELVPLARASVDVFGNRTLLAAGTTDSEGVATLPLSYRLGTWVLVTAARP GFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLGSPGARS QPLVQFQRRAARLPVSSTYSQLWASLTPASTQQEMRAFPAFLGTEASSSG NGSWLELMPLTAVSVHLLTGNGTEVPLSGPIHLSLPVPSETRALTVGTSI PAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTAGL VTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQ HRKLQLSGPSDGNKRDQATSMSQLHLICGGPLEPAPSGDPEAPPPGPLHS AFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESAGLKGARSAEGP GGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFLL SQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLG GEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGG GEGWGAGRAAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPH PRAWFVSLDGRSNSQVRHSYIDLQAGGGARSTDASLDSGVDVHEARPARR RPAREERERAPPAAPPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLT PLLDEVAAPEGRAATVPRGRGRSRGDSSRSSASELRRDSLTSPEDELGAE VGDEAGDKKSPWQRREERPLMVFNVK chromosome location: 44353215-44363875 (17q21.31) Database cross references: | MF: GO:1901363_(0.58)_heterocyclic_compound_binding GO:0097159_(0.58)_organic_cyclic_compound_binding GO:0003676_(0.56)_nucleic_acid_binding GO:0019899_(0.54)_enzyme_binding GO:0017016_(0.52)_Ras_GTPase_binding GO:0022892_(0.47)_substrate-specific_transporter activity GO:0003824_(0.27)_catalytic_activity GO:0016740_(0.16)_transferase_activity GO:0022857_(0.10)_transmembrane_transporter activity GO:0008092_(0.10)_cytoskeletal_protein_binding GO:0022891_(0.09)_substrate-specific_transmembrane transporter_activity GO:0016772_(0.09)_transferase_activity, transferring_phosphorus-containing_groups GO:0005198_(0.09)_structural_molecule_activity GO:0016787_(0.08)_hydrolase_activity GO:0005261_(0.08)_cation_channel_activity BP: GO:0009987_(0.74)_cellular_process GO:0065007_(0.66)_biological_regulation GO:0050789_(0.60)_regulation_of_biological_process GO:0050794_(0.58)_regulation_of_cellular_process GO:0016043_(0.52)_cellular_component_organization GO:0051179_(0.49)_localization GO:0071704_(0.47)_organic_substance_metabolic process GO:0044238_(0.47)_primary_metabolic_process GO:0044699_(0.46)_single-organism_process GO:0043170_(0.46)_macromolecule_metabolic_process GO:0006810_(0.46)_transport GO:0060255_(0.42)_regulation_of_macromolecule metabolic_process GO:0006996_(0.42)_organelle_organization GO:0080090_(0.41)_regulation_of_primary_metabolic process GO:0031323_(0.41)_regulation_of_cellular_metabolic process CC: GO:0043226_(0.90)_organelle GO:0044464_(0.89)_cell_part GO:0043227_(0.88)_membrane-bounded_organelle GO:0044424_(0.87)_intracellular_part GO:0044422_(0.75)_organelle_part GO:0043229_(0.75)_intracellular_organelle GO:0044446_(0.74)_intracellular_organelle_part GO:0043231_(0.73)_intracellular_membrane-bounded organelle GO:0005737_(0.66)_cytoplasm GO:0032991_(0.65)_macromolecular_complex GO:0044444_(0.64)_cytoplasmic_part GO:0043234_(0.64)_protein_complex GO:0031982_(0.53)_vesicle GO:0031988_(0.52)_membrane-bounded_vesicle GO:0044421_(0.51)_extracellular_region_part | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ | ||
31 | >NX_Q96MW1-1|CCD43_HUMAN Coiled-coil domain-containing protein 43 GN=CCDC43 MAAPSEVAAIAPGEGDGGGGGFGSWLDGRLEALGVDRAVYGAYILGILQE EEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEV QAIATLIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDD SGATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRE RDKLAKQERKEKEKKRTQRGERKR chromosome location: 44673069-44689779 (17q21.31) Database cross references: | MF: GO:0008565_(0.13)_protein_transporter_activity GO:0008139_(0.13)_nuclear_localization_sequence binding GO:0005509_(0.10)_calcium_ion_binding GO:0005198_(0.10)_structural_molecule_activity GO:0004871_(0.10)_signal_transducer_activity GO:0004435_(0.10)_phosphatidylinositol phospholipase_C_activity GO:0098641_(0.05)_cadherin_binding_involved_in cell-cell_adhesion GO:0005516_(0.05)_calmodulin_binding BP: GO:0044699_(0.77)_single-organism_process GO:0009987_(0.53)_cellular_process GO:0006810_(0.44)_transport GO:0046907_(0.41)_intracellular_transport GO:0044763_(0.39)_single-organism_cellular_process GO:0006886_(0.38)_intracellular_protein_transport GO:0006606_(0.35)_protein_import_into_nucleus GO:0050794_(0.32)_regulation_of_cellular_process GO:0006607_(0.32)_NLS-bearing_protein_import_into nucleus GO:0016043_(0.29)_cellular_component_organization GO:0071704_(0.25)_organic_substance_metabolic process GO:0044238_(0.25)_primary_metabolic_process GO:0006928_(0.25)_movement_of_cell_or_subcellular component GO:0032502_(0.23)_developmental_process GO:0080090_(0.20)_regulation_of_primary_metabolic process CC: GO:0044464_(1.00)_cell_part GO:0044424_(0.97)_intracellular_part GO:0044422_(0.88)_organelle_part GO:0044446_(0.84)_intracellular_organelle_part GO:0044444_(0.71)_cytoplasmic_part GO:0005829_(0.70)_cytosol GO:0044428_(0.66)_nuclear_part GO:0043226_(0.56)_organelle GO:0005737_(0.53)_cytoplasm GO:0005654_(0.51)_nucleoplasm GO:0016020_(0.50)_membrane GO:0043229_(0.49)_intracellular_organelle GO:0043227_(0.46)_membrane-bounded_organelle GO:0032991_(0.46)_macromolecular_complex GO:0043231_(0.44)_intracellular_membrane-bounded organelle | UniProt annotation: GO:0005829_cytosol GO:0005515_protein_binding UniProt annotation score: ◉◉◉○○ NextProt annotation: GO:0005515_protein_binding | Medium: cells) center_cells;_squamous_epithelial_cells) germinal_center_cells) Langerhans;_melanocytes) cells) | |
32 | >NX_Q9P298-1|HIG1B_HUMAN HIG1 domain family member 1B GN=HIGD1B MSANRRWWVPPDDEDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLR SRGSTKMSIHLIHTRVAAQACAVGAIMLGAVYTMYSDYVKRMAQDAGEK chromosome location: 44846353-44850480 (17q21.31) Database cross references: | MF: GO:0016740_(0.79)_transferase_activity GO:0061630_(0.71)_ubiquitin_protein_ligase activity GO:1901265_(0.28)_nucleoside_phosphate_binding GO:0036094_(0.28)_small_molecule_binding GO:0034061_(0.28)_DNA_polymerase_activity GO:0004527_(0.28)_exonuclease_activity BP: GO:0009987_(0.57)_cellular_process GO:0065007_(0.51)_biological_regulation GO:0043066_(0.32)_negative_regulation_of_apoptotic process GO:0043623_(0.31)_cellular_protein_complex assembly GO:0044699_(0.29)_single-organism_process GO:0044260_(0.26)_cellular_macromolecule_metabolic process GO:0044238_(0.26)_primary_metabolic_process GO:0033617_(0.25)_mitochondrial_respiratory_chain complex_IV_assembly GO:0034654_(0.24)_nucleobase-containing_compound biosynthetic_process GO:0034645_(0.24)_cellular_macromolecule biosynthetic_process GO:0006259_(0.24)_DNA_metabolic_process GO:0055070_(0.19)_copper_ion_homeostasis GO:0048149_(0.19)_behavioral_response_to_ethanol GO:0090201_(0.10)_negative_regulation_of_release of_cytochrome_c_from_mitochondria GO:0071902_(0.10)_positive_regulation_of_protein serine/threonine_kinase_activity CC: GO:0044464_(0.95)_cell_part GO:0044424_(0.94)_intracellular_part GO:0032991_(0.90)_macromolecular_complex GO:0044446_(0.88)_intracellular_organelle_part GO:0043234_(0.88)_protein_complex GO:0043229_(0.86)_intracellular_organelle GO:0044444_(0.85)_cytoplasmic_part GO:0043231_(0.80)_intracellular_membrane-bounded organelle GO:0005634_(0.71)_nucleus GO:0044429_(0.53)_mitochondrial_part GO:0005737_(0.46)_cytoplasm GO:0044428_(0.45)_nuclear_part GO:0044427_(0.45)_chromosomal_part GO:0044425_(0.43)_membrane_part GO:0005739_(0.42)_mitochondrion | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ | ||
33 | >NX_A6NFU0-1|F187A_HUMAN Ig-like V-type domain-containing protein FAM187A GN=FAM187A MHLALTTVLLWAWGLQAFEIVEKENIFQRTPCPAFLMFENAAYLADMSFE LPCHCKPEEVPAVVWFYQKHLGSSHTKVLTDFDGRVLTEAAQVRVGSDML TRFSIRMFSLLVFRAQSEDSGLYFCGTRKGDYFYAYDVDIQNSEGMVATF QDKGQEPFADEYYGHLHVFTTFWEWTPCDRCGVRGEQWRIGLCYLQSPDL SPRYLKAVPDVVSCGSRAVPRKLRTKARDHTPEVLVRSCLVPCEKTKTIR EGVLAIINYVSKVGSRPWVPQVPIQFHQQRLGHGLIISCPGARPEHAVAW DKDRQHLYRTQYLKGVNRSMRVFIDHGNQLHIRFTQLDDRGIYYCWRQGV LVAGFRLGVTSHGHYPASFSDPETRSAVELTLIGYLLITAVFVTIHFCRC CCYLFHCCPSFSP chromosome location: 44899712-44905390 (17q21.31) Database cross references: | MF: GO:0004872_(0.55)_receptor_activity GO:0042802_(0.50)_identical_protein_binding GO:0046983_(0.48)_protein_dimerization_activity GO:0004888_(0.46)_transmembrane_signaling_receptor activity GO:0097367_(0.42)_carbohydrate_derivative_binding GO:0098632_(0.30)_protein_binding_involved_in cell-cell_adhesion GO:0042803_(0.21)_protein_homodimerization activity GO:0005102_(0.21)_receptor_binding GO:0050839_(0.14)_cell_adhesion_molecule_binding GO:0003824_(0.14)_catalytic_activity GO:0016740_(0.12)_transferase_activity GO:0004672_(0.11)_protein_kinase_activity GO:0005198_(0.09)_structural_molecule_activity GO:0003823_(0.09)_antigen_binding GO:0008046_(0.08)_axon_guidance_receptor_activity BP: GO:0044699_(0.82)_single-organism_process GO:0009987_(0.80)_cellular_process GO:0044763_(0.79)_single-organism_cellular_process GO:0065007_(0.65)_biological_regulation GO:0050789_(0.65)_regulation_of_biological_process GO:0006928_(0.64)_movement_of_cell_or_subcellular component GO:0050794_(0.63)_regulation_of_cellular_process GO:0032502_(0.63)_developmental_process GO:0044767_(0.60)_single-organism_developmental process GO:0007411_(0.59)_axon_guidance GO:0048856_(0.55)_anatomical_structure_development GO:0048869_(0.53)_cellular_developmental_process GO:0016043_(0.53)_cellular_component_organization GO:0051239_(0.52)_regulation_of_multicellular organismal_process GO:0007155_(0.52)_cell_adhesion CC: GO:0044464_(0.98)_cell_part GO:0031224_(0.93)_intrinsic_component_of_membrane GO:0016020_(0.92)_membrane GO:0016021_(0.82)_integral_component_of_membrane GO:0005886_(0.71)_plasma_membrane GO:0044459_(0.66)_plasma_membrane_part GO:0097458_(0.59)_neuron_part GO:0044421_(0.55)_extracellular_region_part GO:0043005_(0.53)_neuron_projection GO:0030424_(0.52)_axon GO:0031226_(0.51)_intrinsic_component_of_plasma membrane GO:0005887_(0.50)_integral_component_of_plasma membrane GO:0044424_(0.48)_intracellular_part GO:0030054_(0.43)_cell_junction GO:0043025_(0.40)_neuronal_cell_body | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ | High: | |
34 | >NX_A6NMS7-1|L37A1_HUMAN Leucine-rich repeat-containing protein 37A GN=LRRC37A MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLT SNPLGPPESWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQ ESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKL KKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELR VKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLL EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP MEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHH QTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVE PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAA EHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG FTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ VQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTL PPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPD LGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPA QDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQ RLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVIT ELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLV PLTTLKNILMMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNSAC LTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIVEPEEPSDSSGINL SGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNS LAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA AEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKP FSKGTPSTSSPAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVH ARKKYRFHKTRSHVTHRTTKVKKSPKVRKKSYLSRLMLANRLPFSAAKSL INSPSQGAFSSLGDLSPQENPFLEVSALSEHFIEKNNTKHTTARNAFEEN DFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNV GTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIEN YINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFC LIVICCHRRSLQEDEEGFSRGIFRFLPWRGCSSRRESQDGLSSFGQPLWF KDLYKPLSATRINNHAWKLHKKSSNEDKILNRDPGDSEAPTEEEESEALP chromosome location: 46292733-46337794 (17q21.31) Database cross references: | MF: GO:0098772_(0.27)_molecular_function_regulator GO:0030234_(0.26)_enzyme_regulator_activity GO:0004860_(0.25)_protein_kinase_inhibitor activity GO:0005102_(0.16)_receptor_binding GO:0097367_(0.15)_carbohydrate_derivative_binding GO:0004872_(0.15)_receptor_activity GO:0005539_(0.14)_glycosaminoglycan_binding GO:0008201_(0.13)_heparin_binding GO:0097159_(0.12)_organic_cyclic_compound_binding GO:0003824_(0.12)_catalytic_activity GO:0048495_(0.11)_Roundabout_binding GO:0038023_(0.11)_signaling_receptor_activity GO:0003676_(0.11)_nucleic_acid_binding GO:0004888_(0.08)_transmembrane_signaling_receptor activity GO:0003723_(0.08)_RNA_binding BP: GO:0065007_(0.61)_biological_regulation GO:0050789_(0.59)_regulation_of_biological_process GO:0009987_(0.59)_cellular_process GO:0050794_(0.58)_regulation_of_cellular_process GO:0044699_(0.53)_single-organism_process GO:0044763_(0.47)_single-organism_cellular_process GO:0032502_(0.44)_developmental_process GO:0007165_(0.44)_signal_transduction GO:0044767_(0.42)_single-organism_developmental process GO:0016043_(0.35)_cellular_component_organization GO:0048583_(0.32)_regulation_of_response_to stimulus GO:0007166_(0.30)_cell_surface_receptor_signaling pathway GO:0019222_(0.29)_regulation_of_metabolic_process GO:0009653_(0.29)_anatomical_structure morphogenesis GO:0031323_(0.28)_regulation_of_cellular_metabolic process CC: GO:0044464_(0.78)_cell_part GO:0044424_(0.59)_intracellular_part GO:0005737_(0.38)_cytoplasm GO:0044421_(0.24)_extracellular_region_part GO:0044425_(0.19)_membrane_part GO:0043226_(0.19)_organelle GO:0031012_(0.19)_extracellular_matrix GO:0005615_(0.18)_extracellular_space GO:0043229_(0.16)_intracellular_organelle GO:0005578_(0.16)_proteinaceous_extracellular matrix GO:0044459_(0.15)_plasma_membrane_part GO:0044444_(0.15)_cytoplasmic_part GO:0043227_(0.15)_membrane-bounded_organelle GO:0032991_(0.15)_macromolecular_complex GO:0031224_(0.15)_intrinsic_component_of_membrane | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ | High: early_spermatids) spermatocytes) | |
35 | >NX_A6NM11-1|L37A2_HUMAN Leucine-rich repeat-containing protein 37A2 GN=LRRC37A2 MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLT SNPLGPPDSWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQ ESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKL KKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELR VKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLL EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP MEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHH QTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVE PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAA EHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG FTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ VQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTL PPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPD LGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPA QDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQ RLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVIT ELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLV PLTTLKNILMMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNSAC LTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIVEPEEPSDSSGINL SGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNS LAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKP FSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVH ARKKYRFHKTRSHVTHRTPKVKKSPKVRKKSYLSRLMLANRLPFSAAKSL INSPSQGAFSSLGDLSPQENPFLEVSAPSEHFIENNNTKHTTARNAFEEN DFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQTETKWEYNNV GTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIEN YINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFC LIVICCHRRSLQEDEEGFSRGIFRFLPWRGCSSRRESQDGLSSFGQPLWF KDMYKPLSATRINNHAWKLHKKSSNEDKILNRDPGDSEAPTEEEESEALP chromosome location: 46511511-46555650 (17q21.31) Database cross references: | MF: GO:0098772_(0.27)_molecular_function_regulator GO:0004857_(0.26)_enzyme_inhibitor_activity GO:0004860_(0.25)_protein_kinase_inhibitor activity GO:0097367_(0.16)_carbohydrate_derivative_binding GO:0005102_(0.16)_receptor_binding GO:0004872_(0.16)_receptor_activity GO:0005539_(0.14)_glycosaminoglycan_binding GO:0008201_(0.13)_heparin_binding GO:0048495_(0.12)_Roundabout_binding GO:1901363_(0.11)_heterocyclic_compound_binding GO:0097159_(0.11)_organic_cyclic_compound_binding GO:0038023_(0.11)_signaling_receptor_activity GO:0003824_(0.11)_catalytic_activity GO:0003676_(0.10)_nucleic_acid_binding GO:0004888_(0.08)_transmembrane_signaling_receptor activity BP: GO:0065007_(0.61)_biological_regulation GO:0050789_(0.60)_regulation_of_biological_process GO:0009987_(0.59)_cellular_process GO:0050794_(0.58)_regulation_of_cellular_process GO:0044699_(0.53)_single-organism_process GO:0044763_(0.47)_single-organism_cellular_process GO:0007165_(0.45)_signal_transduction GO:0032502_(0.44)_developmental_process GO:0044767_(0.42)_single-organism_developmental process GO:0016043_(0.35)_cellular_component_organization GO:0048583_(0.32)_regulation_of_response_to stimulus GO:0007166_(0.30)_cell_surface_receptor_signaling pathway GO:0031323_(0.29)_regulation_of_cellular_metabolic process GO:0009653_(0.29)_anatomical_structure morphogenesis GO:0080090_(0.28)_regulation_of_primary_metabolic process CC: GO:0044464_(0.78)_cell_part GO:0044424_(0.58)_intracellular_part GO:0005737_(0.37)_cytoplasm GO:0044421_(0.24)_extracellular_region_part GO:0044425_(0.19)_membrane_part GO:0043226_(0.19)_organelle GO:0031012_(0.19)_extracellular_matrix GO:0005615_(0.18)_extracellular_space GO:0005578_(0.17)_proteinaceous_extracellular matrix GO:0044459_(0.16)_plasma_membrane_part GO:0043229_(0.16)_intracellular_organelle GO:0044444_(0.15)_cytoplasmic_part GO:0043227_(0.15)_membrane-bounded_organelle GO:0031224_(0.15)_intrinsic_component_of_membrane GO:0016020_(0.15)_membrane | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ | High: early_spermatids) spermatocytes) | |
36 | >NX_Q9BU68-1|PR15L_HUMAN Proline-rich protein 15-like protein GN=PRR15L MTTEIGWWKLTFLRKKKSTPKVLYEIPDTYAQTEGDAEPPRPDAGGPNSD FNTRLEKIVDKSTKGKHVKVSNSGRFKEKKKVRATLAENPNLFDDHEEGR SSK chromosome location: 47951967-47957878 (17q21.32) Database cross references: | MF: GO:0044877_(0.31)_macromolecular_complex_binding GO:0005524_(0.31)_ATP_binding GO:0004672_(0.31)_protein_kinase_activity BP: GO:0018108_(0.42)_peptidyl-tyrosine phosphorylation GO:0008283_(0.42)_cell_proliferation GO:0006955_(0.42)_immune_response GO:0006952_(0.42)_defense_response GO:2001236_(0.31)_regulation_of_extrinsic apoptotic_signaling_pathway GO:2001234_(0.31)_negative_regulation_of_apoptotic signaling_pathway GO:0043068_(0.31)_positive_regulation_of programmed_cell_death GO:0022610_(0.31)_biological_adhesion CC: GO:0044464_(0.95)_cell_part GO:0044424_(0.89)_intracellular_part GO:0005737_(0.84)_cytoplasm GO:0016020_(0.74)_membrane GO:0044425_(0.68)_membrane_part GO:0044444_(0.63)_cytoplasmic_part GO:0044459_(0.58)_plasma_membrane_part GO:0043226_(0.58)_organelle GO:0005829_(0.58)_cytosol GO:0043227_(0.53)_membrane-bounded_organelle GO:0043231_(0.47)_intracellular_membrane-bounded organelle GO:0098590_(0.37)_plasma_membrane_region GO:0005886_(0.37)_plasma_membrane GO:0044446_(0.32)_intracellular_organelle_part GO:0043234_(0.32)_protein_complex | UniProt annotation score: ◉○○○○ | High: Langerhans) Langerhans;_melanocytes) molecular_layer) neuropil) epithelial_cells) | |
37 | >NX_Q9C073-1|F117A_HUMAN FAM117A GN=FAM117A MAGAAAGGRGGGAWGPGRGGAGGLRRGCSPPAPAGSPRAGLQPLRATIPF QLQQPHQRRDGGGRAASVPCSVAPEKSVCRPQPLQVRRTFSLDTILSSYL LGQWPRDADGAFTCCTNDKATQTPLSWQELEGERASSCAHKRSASWGSTD HRKEISKLKQQLQRTKLSRSGKEKERGSPLLGDHAVRGALRASPPSFPSG SPVLRLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILDIPDGHRAPAPP QSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTP NDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVF EEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRN CPSNPGSPLPPASPRPPPRKDPEASKASPLPFEPWQRTPPSEEPVLFQSS LMV chromosome location: 49710332-49789180 (17q21.33) Database cross references: | MF: GO:0022891_(0.51)_substrate-specific_transmembrane transporter_activity GO:0005459_(0.40)_UDP-galactose_transmembrane transporter_activity GO:0003824_(0.23)_catalytic_activity GO:0072341_(0.17)_modified_amino_acid_binding GO:0033218_(0.17)_amide_binding GO:0019842_(0.17)_vitamin_binding GO:0005261_(0.10)_cation_channel_activity GO:0022843_(0.09)_voltage-gated_cation_channel activity GO:0005262_(0.09)_calcium_channel_activity GO:0005245_(0.08)_voltage-gated_calcium_channel activity GO:0016740_(0.06)_transferase_activity GO:0008092_(0.06)_cytoskeletal_protein_binding GO:0016772_(0.05)_transferase_activity, transferring_phosphorus-containing_groups GO:0008331_(0.05)_high_voltage-gated_calcium channel_activity GO:0008332_(0.04)_low_voltage-gated_calcium channel_activity BP: GO:0044699_(0.84)_single-organism_process GO:0009987_(0.62)_cellular_process GO:0044763_(0.55)_single-organism_cellular_process GO:0032501_(0.48)_multicellular_organismal_process GO:0044767_(0.46)_single-organism_developmental process GO:0048856_(0.44)_anatomical_structure_development GO:0048869_(0.42)_cellular_developmental_process GO:0003008_(0.40)_system_process GO:0051179_(0.37)_localization GO:0072015_(0.36)_glomerular_visceral_epithelial cell_development GO:0006810_(0.36)_transport GO:0003094_(0.36)_glomerular_filtration GO:0044765_(0.28)_single-organism_transport GO:0071702_(0.26)_organic_substance_transport GO:0065007_(0.26)_biological_regulation CC: GO:0044464_(1.00)_cell_part GO:0044424_(0.96)_intracellular_part GO:0044444_(0.62)_cytoplasmic_part GO:0005737_(0.57)_cytoplasm GO:0044422_(0.38)_organelle_part GO:0044446_(0.36)_intracellular_organelle_part GO:0043229_(0.35)_intracellular_organelle GO:0032991_(0.29)_macromolecular_complex GO:0043234_(0.28)_protein_complex GO:0044425_(0.25)_membrane_part GO:0043227_(0.25)_membrane-bounded_organelle GO:0043231_(0.24)_intracellular_membrane-bounded organelle GO:0016021_(0.22)_integral_component_of_membrane GO:0044431_(0.21)_Golgi_apparatus_part GO:0030176_(0.21)_integral_component_of endoplasmic_reticulum_membrane | UniProt annotation score: ◉◉○○○ | High: peripheral_nerve/ganglion) center_cells;_squamous_epithelial_cells) cells;_neuronal_cells) molecular_layer) peripheral_nerve) melanocytes) | |
38 | >NX_Q8IZD0-1|SAM14_HUMAN Sterile alpha motif domain-containing protein 14 GN=SAMD14 MASSKLREPVDEVFDLDLAVPETARLDSSLHKARAQLLAKGRRHRPSRSR LRDSASSAEDGEGSDGPGGKVTDGCGSPLHRLRSPLHSGPGSPAGGSFCL DPPGLRRSLDEDEPPPSPLTRYRPLHNAASHEGLAAASCSPPRSAPSSDS SPSFVRRHPRAEPHSEDDSRDASPPEPASPTIGLDKKTRRKFLDLGVTLR RASTGKSRKEKGSNRLSMGSRESVEGSGRSGGSPFLPFSWFTDSGKGSAS SGSTTSPTCSPKHEGFSPKKSASQESTLSDDSTPPSSSPKIPSGPWQEAK CSYPYHTLSQSSDEFLDEPLPPVHHWTSQQVGQWLQSLNLEQYAAEFAAR QVDGPQLLQLDGSKLKSLGLSNSHDRALVKRKLKEMAAAAEKERKAQEKA ARQREKLRRREQEAKKS chromosome location: 50110040-50129882 (17q21.33) Database cross references: | MF: GO:0003824_(0.55)_catalytic_activity GO:0044877_(0.48)_macromolecular_complex_binding GO:0032403_(0.47)_protein_complex_binding GO:0051015_(0.45)_actin_filament_binding GO:1901363_(0.43)_heterocyclic_compound_binding GO:0097159_(0.43)_organic_cyclic_compound_binding GO:0043169_(0.42)_cation_binding GO:0097367_(0.41)_carbohydrate_derivative_binding GO:0017076_(0.41)_purine_nucleotide_binding GO:0035639_(0.40)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.40)_adenyl_ribonucleotide_binding GO:0032550_(0.40)_purine_ribonucleoside_binding GO:0016879_(0.40)_ligase_activity,_forming_carbon- nitrogen_bonds GO:0016421_(0.25)_CoA_carboxylase_activity GO:0016740_(0.13)_transferase_activity BP: GO:0044699_(0.84)_single-organism_process GO:0009987_(0.83)_cellular_process GO:0065007_(0.80)_biological_regulation GO:0050789_(0.78)_regulation_of_biological_process GO:0044763_(0.75)_single-organism_cellular_process GO:0050794_(0.73)_regulation_of_cellular_process GO:0016043_(0.64)_cellular_component_organization GO:0007165_(0.61)_signal_transduction GO:0030030_(0.49)_cell_projection_organization GO:0035556_(0.47)_intracellular_signal transduction GO:0019932_(0.46)_second-messenger-mediated signaling GO:0031175_(0.45)_neuron_projection_development GO:0019722_(0.45)_calcium-mediated_signaling GO:0007015_(0.44)_actin_filament_organization GO:0071704_(0.37)_organic_substance_metabolic process CC: GO:0044424_(1.00)_intracellular_part GO:0043226_(0.84)_organelle GO:0043229_(0.83)_intracellular_organelle GO:0044444_(0.81)_cytoplasmic_part GO:0005737_(0.81)_cytoplasm GO:0044446_(0.64)_intracellular_organelle_part GO:0043232_(0.61)_intracellular_non-membrane- bounded_organelle GO:0043231_(0.61)_intracellular_membrane-bounded organelle GO:0097458_(0.53)_neuron_part GO:0042995_(0.51)_cell_projection GO:0044456_(0.50)_synapse_part GO:0043005_(0.50)_neuron_projection GO:0016020_(0.50)_membrane GO:0005856_(0.50)_cytoskeleton GO:0015629_(0.42)_actin_cytoskeleton | UniProt annotation score: ◉◉○○○ | ||
39 | >NX_Q6AI12-1|ANR40_HUMAN Ankyrin repeat domain-containing protein 40 GN=ANKRD40 MNALLEQKEQQERLREAAALGDIREVQKLVESGVDVNSQNEVNGWTCLHW ACKRNHGQVVSYLLKSGADKEILTTKGEMPVQLTSRREIRKIMGVEEEDD DDDDDDNLPQLKKESELPFVPNYLANPAFPFIYTPTAEDSAQMQNGGPST PPASPPADGSPPLLPPGEPPLLGTFPRDHTSLALVQNGDVSAPSAILRTP ESTKPGPVCQPPVSQSRSLFSSVPSKPPMSLEPQNGTYAGPAPAFQPFFF TGAFPFNMQELVLKVRIQNPSLRENDFIEIELDRQELTYQELLRVCCCEL GVNPDQVEKIRKLPNTLLRKDKDVARLQDFQELELVLMISENNFLFRNAA STLTERPCYNRRASKLTY chromosome location: 50693190-50707924 (17q21.33) Database cross references: | MF: GO:0019899_(0.64)_enzyme_binding GO:0044389_(0.62)_ubiquitin-like_protein_ligase binding GO:0008092_(0.62)_cytoskeletal_protein_binding GO:0030507_(0.57)_spectrin_binding GO:0008093_(0.57)_cytoskeletal_adaptor_activity GO:0044877_(0.51)_macromolecular_complex_binding GO:0008134_(0.51)_transcription_factor_binding GO:0005048_(0.50)_signal_sequence_binding GO:0005200_(0.49)_structural_constituent_of cytoskeleton GO:0051117_(0.48)_ATPase_binding GO:0003824_(0.33)_catalytic_activity GO:0016740_(0.30)_transferase_activity GO:0044325_(0.29)_ion_channel_binding GO:0019901_(0.29)_protein_kinase_binding GO:0004842_(0.26)_ubiquitin-protein_transferase activity BP: GO:0065007_(0.82)_biological_regulation GO:0050789_(0.78)_regulation_of_biological_process GO:0050794_(0.77)_regulation_of_cellular_process GO:0009987_(0.76)_cellular_process GO:0044699_(0.72)_single-organism_process GO:0044763_(0.66)_single-organism_cellular_process GO:0060255_(0.62)_regulation_of_macromolecule metabolic_process GO:0007165_(0.62)_signal_transduction GO:0080090_(0.61)_regulation_of_primary_metabolic process GO:0031323_(0.61)_regulation_of_cellular_metabolic process GO:0051179_(0.60)_localization GO:0048522_(0.60)_positive_regulation_of_cellular process GO:0016043_(0.60)_cellular_component_organization GO:0065008_(0.58)_regulation_of_biological_quality GO:0050896_(0.58)_response_to_stimulus CC: GO:0044464_(0.99)_cell_part GO:0044424_(0.94)_intracellular_part GO:0043229_(0.86)_intracellular_organelle GO:0043227_(0.80)_membrane-bounded_organelle GO:0043231_(0.79)_intracellular_membrane-bounded organelle GO:0005737_(0.77)_cytoplasm GO:0044444_(0.66)_cytoplasmic_part GO:0005634_(0.65)_nucleus GO:0016020_(0.63)_membrane GO:0044425_(0.56)_membrane_part GO:0005886_(0.55)_plasma_membrane GO:0032991_(0.53)_macromolecular_complex GO:0044459_(0.51)_plasma_membrane_part GO:0044422_(0.51)_organelle_part GO:0043234_(0.51)_protein_complex | UniProt annotation: GO:0005515_protein_binding UniProt annotation score: ◉◉◉○○ NextProt annotation: GO:0005515_protein_binding | High: peripheral_nerve/ganglion) center_cells;_squamous_epithelial_cells) glandular_cells) Langerhans) cells;_neuronal_cells) germinal_center_cells) epithelial_cells) molecular_layer;_Purkinje_cells) pulp) fibroblasts;_peripheral_nerve) Langerhans;_melanocytes) | |
40 | >NX_Q0P5P2-1|CQ067_HUMAN Uncharacterized protein C17orf67 GN=C17orf67 MASFKLADSVWEDSLSKRQRNQGRMKTLPVLVLSLTLLTVFSETSPILTE KQAKQLLRSRRQDRPSKPGFPDEPMREYMHHLLALEHRAEEQFLEHWLNP HCKPHCDRNRIHPV chromosome location: 56791913-56838773 (17q22) Database cross references: | MF: GO:0043169_(0.58)_cation_binding GO:0004112_(0.58)_cyclic-nucleotide phosphodiesterase_activity GO:0032561_(0.48)_guanyl_ribonucleotide_binding GO:0030551_(0.48)_cyclic_nucleotide_binding BP: GO:0046068_(0.48)_cGMP_metabolic_process GO:0009214_(0.48)_cyclic_nucleotide_catabolic process GO:0009154_(0.48)_purine_ribonucleotide_catabolic process GO:2000243_(0.37)_positive_regulation_of reproductive_process GO:1900542_(0.37)_regulation_of_purine_nucleotide metabolic_process GO:0090075_(0.37)_relaxation_of_muscle GO:0071902_(0.37)_positive_regulation_of_protein serine/threonine_kinase_activity GO:0060281_(0.37)_regulation_of_oocyte_development GO:0055117_(0.37)_regulation_of_cardiac_muscle contraction GO:0050868_(0.37)_negative_regulation_of_T_cell activation GO:0050672_(0.37)_negative_regulation_of lymphocyte_proliferation GO:0045988_(0.37)_negative_regulation_of_striated muscle_contraction GO:0045822_(0.37)_negative_regulation_of_heart contraction GO:0043902_(0.37)_positive_regulation_of_multi- organism_process GO:0043410_(0.37)_positive_regulation_of_MAPK cascade CC: GO:0044464_(1.00)_cell_part GO:0044424_(0.87)_intracellular_part GO:0044444_(0.73)_cytoplasmic_part GO:0005829_(0.53)_cytosol GO:0043226_(0.47)_organelle GO:0005737_(0.47)_cytoplasm GO:0043229_(0.33)_intracellular_organelle GO:0016020_(0.33)_membrane GO:0044446_(0.27)_intracellular_organelle_part GO:0043227_(0.27)_membrane-bounded_organelle GO:0097458_(0.20)_neuron_part GO:0043231_(0.20)_intracellular_membrane-bounded organelle GO:0005886_(0.20)_plasma_membrane GO:0098590_(0.13)_plasma_membrane_region GO:0044421_(0.13)_extracellular_region_part | UniProt annotation: GO:0005515_protein_binding GO:0005576_extracellular_region UniProt annotation score: ◉◉○○○ NextProt annotation: GO:0005515_protein_binding | ||
41 | >NX_Q9NWM3-1|CUED1_HUMAN CUE domain-containing protein 1 GN=CUEDC1 MTSLFRRSSSGSGGGGTAGARGGGGGTAAPQELNNSRPARQVRRLEFNQA MDDFKTMFPNMDYDIIECVLRANSGAVDATIDQLLQMNLEGGGSSGGVYE DSSDSEDSIPPEILERTLEPDSSDEEPPPVYSPPAYHMHVFDRPYPLAPP TPPPRIDALGSGAPTSQRRYRNWNPPLLGNLPDDFLRILPQQLDSIQGNA GGPKPGSGEGCPPAMAGPGPGDQESRWKQYLEDERIALFLQNEEFMKELQ RNRDFLLALERDRLKYESQKSKSSSVAVGNDFGFSSPVPGTGDANPAVSE DALFRDKLKHMGKSTRRKLFELARAFSEKTKMRKSKRKHLLKHQSLGAAA STANLLDDVEGHACDEDFRGRRQEAPKVEEGLREGQ chromosome location: 57861243-57955323 (17q22) Database cross references: | MF: GO:0022892_(0.35)_substrate-specific_transporter activity GO:0019899_(0.32)_enzyme_binding GO:0008331_(0.26)_high_voltage-gated_calcium channel_activity GO:0005102_(0.23)_receptor_binding GO:0042393_(0.20)_histone_binding GO:0046872_(0.18)_metal_ion_binding GO:0035325_(0.17)_Toll-like_receptor_binding GO:0019900_(0.17)_kinase_binding GO:0030234_(0.15)_enzyme_regulator_activity GO:0051879_(0.12)_Hsp90_protein_binding GO:0044822_(0.12)_poly(A)_RNA_binding GO:0019904_(0.12)_protein_domain_specific_binding GO:0008565_(0.12)_protein_transporter_activity GO:0008536_(0.12)_Ran_GTPase_binding GO:0008270_(0.12)_zinc_ion_binding BP: GO:0009987_(0.94)_cellular_process GO:0065007_(0.58)_biological_regulation GO:0044237_(0.58)_cellular_metabolic_process GO:0006796_(0.55)_phosphate-containing_compound metabolic_process GO:0050794_(0.52)_regulation_of_cellular_process GO:0016310_(0.52)_phosphorylation GO:0044763_(0.40)_single-organism_cellular_process GO:0022402_(0.28)_cell_cycle_process GO:0080090_(0.27)_regulation_of_primary_metabolic process GO:0050896_(0.27)_response_to_stimulus GO:0031325_(0.27)_positive_regulation_of_cellular metabolic_process GO:0010604_(0.27)_positive_regulation_of macromolecule_metabolic_process GO:0007267_(0.24)_cell-cell_signaling GO:0045944_(0.23)_positive_regulation_of transcription_from_RNA_polymerase_II_promoter GO:0033365_(0.23)_protein_localization_to organelle CC: GO:0044424_(1.00)_intracellular_part GO:0043227_(0.90)_membrane-bounded_organelle GO:0005634_(0.85)_nucleus GO:0044446_(0.81)_intracellular_organelle_part GO:0005737_(0.75)_cytoplasm GO:0044428_(0.66)_nuclear_part GO:0016020_(0.60)_membrane GO:0043234_(0.58)_protein_complex GO:0070062_(0.56)_extracellular_exosome GO:0044444_(0.56)_cytoplasmic_part GO:0005643_(0.54)_nuclear_pore GO:0005829_(0.36)_cytosol GO:0005654_(0.30)_nucleoplasm GO:0044459_(0.24)_plasma_membrane_part GO:1902494_(0.23)_catalytic_complex | UniProt annotation score: ◉◉○○○ | High: peripheral_nerve/ganglion) cells) epithelial_cells) cells;_neuropil) epithelial_cells) molecular_layer) peripheral_nerve) melanocytes) pulp) | |
42 | >NX_Q8NEP4-1|CQ047_HUMAN Uncharacterized protein C17orf47 GN=C17orf47 MVKTNKPGAKVAVSAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSH RRSEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPRGPETGPRTESSRHS SPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHASSI PDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGVRVPRRILSYPKDE AVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESET GPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYS AYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHV TVPSVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKP SIHAELELTPRPLPPRSLPRYGPDSSWWPLLNPEVETPQSQLTTPDFEPK CSPSLDLLLSGFKIDSSPFCEDLKFQREKASLSPPSPPKEFPSWAPLSEV PQTPKHTCKQPIQRFTAFFLDVSEEMYNRVIWWLKGLCFSLLWAHCGSLG DGRTGEEWHLCIYRAGSFRR chromosome location: 58541587-58544368 (17q22) Database cross references: | MF: GO:1901363_(0.37)_heterocyclic_compound_binding GO:0097159_(0.37)_organic_cyclic_compound_binding GO:0003676_(0.35)_nucleic_acid_binding GO:0003824_(0.21)_catalytic_activity GO:0022892_(0.18)_substrate-specific_transporter activity GO:0015075_(0.17)_ion_transmembrane_transporter activity GO:0008324_(0.16)_cation_transmembrane_transporter activity GO:0005216_(0.16)_ion_channel_activity GO:0005261_(0.15)_cation_channel_activity GO:0046873_(0.13)_metal_ion_transmembrane transporter_activity GO:0008092_(0.13)_cytoskeletal_protein_binding GO:0022843_(0.12)_voltage-gated_cation_channel activity GO:0016740_(0.12)_transferase_activity GO:0015085_(0.12)_calcium_ion_transmembrane transporter_activity GO:0005262_(0.11)_calcium_channel_activity BP: GO:0009987_(0.59)_cellular_process GO:0044699_(0.51)_single-organism_process GO:0065007_(0.50)_biological_regulation GO:0044763_(0.42)_single-organism_cellular_process GO:0050789_(0.39)_regulation_of_biological_process GO:0050794_(0.38)_regulation_of_cellular_process GO:0044767_(0.27)_single-organism_developmental process GO:0016043_(0.26)_cellular_component_organization GO:0065008_(0.25)_regulation_of_biological_quality GO:0032501_(0.24)_multicellular_organismal_process GO:0008152_(0.22)_metabolic_process GO:0071704_(0.21)_organic_substance_metabolic process GO:0051179_(0.21)_localization GO:0044238_(0.21)_primary_metabolic_process GO:0044237_(0.21)_cellular_metabolic_process CC: GO:0044464_(0.97)_cell_part GO:0044424_(0.95)_intracellular_part GO:0032991_(0.69)_macromolecular_complex GO:0043234_(0.68)_protein_complex GO:0044444_(0.60)_cytoplasmic_part GO:0043226_(0.57)_organelle GO:0043229_(0.56)_intracellular_organelle GO:0044422_(0.47)_organelle_part GO:0044446_(0.45)_intracellular_organelle_part GO:0005737_(0.41)_cytoplasm GO:0043227_(0.40)_membrane-bounded_organelle GO:0043231_(0.38)_intracellular_membrane-bounded organelle GO:1990234_(0.34)_transferase_complex GO:0043232_(0.33)_intracellular_non-membrane- bounded_organelle GO:0016020_(0.33)_membrane | UniProt annotation score: ◉○○○○ | ||
43 | >NX_Q86X59-1|CQ082_HUMAN Putative uncharacterized protein C17orf82 GN=C17orf82 MGRPLEGQPLRALDLYPEPAFLRSGKDPKSSPASSPSFAVLGPEVRSTGG QAGSRRRPSAPCSQDRAAAEGAPALLGGSPSSGSPGHPPGSAFGVEAGCR ALNVSEHARGGFALGLPFGLSGGAYLFLLLDGAGDPKPTPEAPISSADGR AWFPSESSWQLPQLPAGSTSGSEPRARPGLGPRQLLTGPRDGAAGQGPGR GLTARLGREREIDCGPRQAGHGGTATDTGRAGSGARHRPPRDRGTPGLRT H chromosome location: 61411751-61413280 (17q23.2) Database cross references: | MF: GO:0015926_(0.39)_glucosidase_activity GO:0003676_(0.34)_nucleic_acid_binding BP: GO:0009987_(0.69)_cellular_process GO:0016043_(0.55)_cellular_component_organization GO:0032502_(0.52)_developmental_process GO:0044699_(0.49)_single-organism_process GO:0048856_(0.48)_anatomical_structure_development GO:0051179_(0.45)_localization GO:0071704_(0.44)_organic_substance_metabolic process GO:0006810_(0.44)_transport GO:0043170_(0.43)_macromolecule_metabolic_process GO:0044238_(0.42)_primary_metabolic_process GO:0044237_(0.42)_cellular_metabolic_process GO:0043933_(0.42)_macromolecular_complex_subunit organization GO:0022607_(0.42)_cellular_component_assembly GO:0044260_(0.40)_cellular_macromolecule_metabolic process GO:0065003_(0.39)_macromolecular_complex_assembly CC: GO:0044464_(0.80)_cell_part GO:0044424_(0.65)_intracellular_part GO:0005576_(0.53)_extracellular_region GO:0016020_(0.48)_membrane GO:0005737_(0.44)_cytoplasm GO:0032991_(0.41)_macromolecular_complex GO:0044444_(0.40)_cytoplasmic_part GO:0043234_(0.39)_protein_complex GO:0044422_(0.38)_organelle_part GO:0044446_(0.36)_intracellular_organelle_part GO:0005886_(0.33)_plasma_membrane GO:0043226_(0.31)_organelle GO:0043229_(0.27)_intracellular_organelle GO:0043227_(0.27)_membrane-bounded_organelle GO:0005829_(0.27)_cytosol | UniProt annotation: GO:0005515_protein_binding UniProt annotation score: ◉○○○○ NextProt annotation: GO:0005515_protein_binding | ||
44 | >NX_Q8N7B9-1|EFCB3_HUMAN EF-hand calcium-binding domain-containing protein 3 GN=EFCAB3 MAVSEIKPKLKLNPLTKVPISHNKRDRDLPGSLQCQLQHKEKKLSASQMA AFQDAYNFFYKDKTGCIDFHGLMCTVAKLGMNLTKHDVYNELKCADIDRD GKVNFSDFIKVLTDKNLFLKAVVPEKETCLDLAGNPGILLFEILSRLLET SALPRKSIIEIVSYFQRKFQHTGPGMLWSPYTMGYGKRTLKPDICTPPSS SMAAFANAARIAIMKEKDLFKFLEELKRCNSGSDSPYSKIPIFPLFPNVD GVVMGKPFKDMQKLEMLRIKEPLHFFEDYFFHKRDWKTQAANIKSMDPAS GYSNNIFTIDQMLKKKQTCTVADATAIKQHVKRATDTYNLGIALEHRKEM LNLWQKIRGDLIGMDSRNESFYDTFSTYTWSWNVCQELLSPKDLRLYDAY VNRNSSHNSRSSSSSDTSECYTDSGRKRKRKGLKGFQQ chromosome location: 62343941-62416479 (17q23.2) Database cross references: | MF: GO:0043169_(0.74)_cation_binding GO:0005509_(0.47)_calcium_ion_binding GO:0003824_(0.34)_catalytic_activity GO:0004672_(0.28)_protein_kinase_activity GO:0009931_(0.27)_calcium-dependent_protein serine/threonine_kinase_activity GO:0005516_(0.27)_calmodulin_binding GO:0004683_(0.27)_calmodulin-dependent_protein kinase_activity GO:0008092_(0.13)_cytoskeletal_protein_binding GO:0005198_(0.10)_structural_molecule_activity GO:0003735_(0.07)_structural_constituent_of ribosome GO:0042803_(0.06)_protein_homodimerization activity GO:0016787_(0.06)_hydrolase_activity GO:0051393_(0.05)_alpha-actinin_binding GO:0017166_(0.05)_vinculin_binding GO:0098772_(0.04)_molecular_function_regulator BP: GO:0009987_(0.80)_cellular_process GO:0065007_(0.64)_biological_regulation GO:0071704_(0.61)_organic_substance_metabolic process GO:0050789_(0.61)_regulation_of_biological_process GO:0044238_(0.60)_primary_metabolic_process GO:0043170_(0.59)_macromolecule_metabolic_process GO:0019538_(0.58)_protein_metabolic_process GO:0050794_(0.56)_regulation_of_cellular_process GO:0044237_(0.55)_cellular_metabolic_process GO:0044260_(0.53)_cellular_macromolecule_metabolic process GO:0044267_(0.52)_cellular_protein_metabolic process GO:0007165_(0.46)_signal_transduction GO:0050896_(0.43)_response_to_stimulus GO:0035556_(0.43)_intracellular_signal transduction GO:0006796_(0.42)_phosphate-containing_compound metabolic_process CC: GO:0044464_(1.00)_cell_part GO:0044424_(0.99)_intracellular_part GO:0043226_(0.91)_organelle GO:0043229_(0.87)_intracellular_organelle GO:0043227_(0.82)_membrane-bounded_organelle GO:0016020_(0.82)_membrane GO:0044444_(0.80)_cytoplasmic_part GO:0043231_(0.80)_intracellular_membrane-bounded organelle GO:0005737_(0.68)_cytoplasm GO:0005886_(0.66)_plasma_membrane GO:0044422_(0.64)_organelle_part GO:0005634_(0.62)_nucleus GO:0044446_(0.59)_intracellular_organelle_part GO:0044425_(0.56)_membrane_part GO:0043234_(0.45)_protein_complex | UniProt annotation: GO:0005509_calcium_ion_binding GO:0046872_metal_ion_binding UniProt annotation score: ◉◉○○○ NextProt annotation: GO:0005509_calcium_ion_binding | ||
45 | >NX_Q96GE4-1|CEP95_HUMAN Centrosomal protein of 95 kDa GN=CEP95 MAGSDAEWVTIANNLLFKCHIHLRIHELQDCDANVFIALYQSILGEKVPD LIVIPRSQEDDAHNVQAVIDSLALDYLQVSLSHITGENIVKGDKESIKNL LEIFDGLLEYLTERISETSHEKSETEQYFKESDRGERLEEPESTKESKSS WKRVSFGRCSLSSEMLGPSWDGDEAESTGEIIRLGDTAHTFSLRSNGAQC PNEMLSKKALASPSSKSHEDMLYPPSVLSKSRTSFVEDTETLSVSGIPNA RKLGEPIRAAIPLHPPYHPSEPRAPCPIGKEYLHSSHCSPAVNSTGEHTE FSGDLDDGLFLISKLPKGSKWEVYPAQVQGPRTRKPPKGKRNENRATASS CNSPFPQRPRKRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDH KEENTGNEEVEDGTEETLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSL SPSPVNKHKQFHLERKRQRKPRETDVRQFQAQAFTEAFERELRRHKVQEN IGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKTTTQSLRGGLP KPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKE ACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQR LTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGL NIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQE HQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELE AERFRSRLQLASFQYSKSPSL chromosome location: 64506588-64542461 (17q23.3) Database cross references: | MF: GO:0035639_(0.32)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.32)_adenyl_ribonucleotide_binding GO:0032550_(0.32)_purine_ribonucleoside_binding GO:0003676_(0.32)_nucleic_acid_binding GO:0003824_(0.29)_catalytic_activity BP: GO:0009987_(0.71)_cellular_process GO:0044699_(0.61)_single-organism_process GO:0044763_(0.55)_single-organism_cellular_process GO:0016043_(0.38)_cellular_component_organization GO:0065007_(0.37)_biological_regulation GO:0050789_(0.36)_regulation_of_biological_process GO:0050794_(0.35)_regulation_of_cellular_process GO:0051179_(0.27)_localization GO:0007017_(0.26)_microtubule-based_process GO:0032502_(0.25)_developmental_process GO:0006928_(0.25)_movement_of_cell_or_subcellular component GO:0044767_(0.24)_single-organism_developmental process GO:0008152_(0.23)_metabolic_process GO:0006996_(0.23)_organelle_organization GO:0071704_(0.22)_organic_substance_metabolic process CC: GO:0005813_(1.00)_centrosome GO:0000922_(1.00)_spindle_pole | UniProt annotation: GO:0005813_centrosome GO:0000922_spindle_pole GO:0005515_protein_binding GO:0005815_microtubule_organizing_center GO:0005737_cytoplasm GO:0005856_cytoskeleton UniProt annotation score: ◉◉◉◉○ NextProt annotation: GO:0005515_protein_binding | High: glandular_cells) epithelial_cells) Langerhans;_melanocytes) | |
46 | >NX_O60309-1|L37A3_HUMAN Leucine-rich repeat-containing protein 37A3 GN=LRRC37A3 MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLT SNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQ ESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKL KKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELR VKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLL EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP MEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHH QTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVE PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAA EHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG FTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ VQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTL PPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPD LGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPA QDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQ RLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVIT ELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLV PLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSAC LTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINL SGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNS LAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENT AEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKP FSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVH SRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSL INSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEEN VFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNV GTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRT LKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTEN YINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLC LIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP chromosome location: 64854312-64919480 (17q24.1) Database cross references: | MF: GO:0098772_(0.29)_molecular_function_regulator GO:0004860_(0.28)_protein_kinase_inhibitor activity GO:0097367_(0.17)_carbohydrate_derivative_binding GO:0005102_(0.17)_receptor_binding GO:0004872_(0.16)_receptor_activity GO:0005539_(0.15)_glycosaminoglycan_binding GO:0008201_(0.14)_heparin_binding GO:0048495_(0.13)_Roundabout_binding GO:0004871_(0.12)_signal_transducer_activity GO:0038023_(0.11)_signaling_receptor_activity GO:0003824_(0.10)_catalytic_activity GO:0003676_(0.10)_nucleic_acid_binding GO:0004888_(0.08)_transmembrane_signaling_receptor activity GO:0003723_(0.07)_RNA_binding GO:0004930_(0.06)_G-protein_coupled_receptor activity BP: GO:0065007_(0.62)_biological_regulation GO:0050789_(0.60)_regulation_of_biological_process GO:0050794_(0.59)_regulation_of_cellular_process GO:0009987_(0.59)_cellular_process GO:0044699_(0.54)_single-organism_process GO:0044763_(0.48)_single-organism_cellular_process GO:0007165_(0.47)_signal_transduction GO:0032502_(0.45)_developmental_process GO:0044767_(0.44)_single-organism_developmental process GO:0016043_(0.35)_cellular_component_organization GO:0048583_(0.34)_regulation_of_response_to stimulus GO:0007166_(0.32)_cell_surface_receptor_signaling pathway GO:0009653_(0.31)_anatomical_structure morphogenesis GO:0019222_(0.30)_regulation_of_metabolic_process GO:0048869_(0.29)_cellular_developmental_process CC: GO:0044464_(0.77)_cell_part GO:0044424_(0.57)_intracellular_part GO:0005737_(0.38)_cytoplasm GO:0044421_(0.26)_extracellular_region_part GO:0044425_(0.20)_membrane_part GO:0031012_(0.20)_extracellular_matrix GO:0043226_(0.19)_organelle GO:0005615_(0.19)_extracellular_space GO:0005578_(0.18)_proteinaceous_extracellular matrix GO:0044459_(0.16)_plasma_membrane_part GO:0031224_(0.16)_intrinsic_component_of_membrane GO:0016020_(0.16)_membrane GO:0043229_(0.15)_intracellular_organelle GO:0043227_(0.15)_membrane-bounded_organelle GO:0044444_(0.14)_cytoplasmic_part | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ | High: early_spermatids) spermatocytes) | |
47 | >NX_Q2M2W7-1|CQ058_HUMAN UPF0450 protein C17orf58 GN=C17orf58 MNRLYLTPDGFFFRVHMLALDSSSCNKPCPEFKPGSRYIVMGHIYHKRRQ LPTALLQVLRGRLRPGDGLLRSSSSYVKRFNRKREGQIQGAIHTQCI chromosome location: 67991101-67996431 (17q24.2) Database cross references: | MF: GO:0046872_(0.13)_metal_ion_binding GO:0008191_(0.13)_metalloendopeptidase_inhibitor activity GO:0004252_(0.13)_serine-type_endopeptidase activity GO:0002020_(0.13)_protease_binding GO:0048037_(0.07)_cofactor_binding GO:0031715_(0.07)_C5L2_anaphylatoxin_chemotactic receptor_binding GO:0016504_(0.07)_peptidase_activator_activity GO:0008289_(0.07)_lipid_binding GO:0008201_(0.07)_heparin_binding GO:0008083_(0.07)_growth_factor_activity GO:0005518_(0.07)_collagen_binding GO:0005125_(0.07)_cytokine_activity GO:0001849_(0.07)_complement_component_C1q_binding BP: GO:0052548_(0.37)_regulation_of_endopeptidase activity GO:0010466_(0.37)_negative_regulation_of_peptidase activity CC: GO:0044464_(0.80)_cell_part GO:0043227_(0.80)_membrane-bounded_organelle GO:0005615_(0.67)_extracellular_space GO:0005576_(0.67)_extracellular_region GO:0031988_(0.60)_membrane-bounded_vesicle GO:0070062_(0.53)_extracellular_exosome GO:0044424_(0.47)_intracellular_part GO:0044446_(0.33)_intracellular_organelle_part GO:0043231_(0.33)_intracellular_membrane-bounded organelle GO:0016020_(0.33)_membrane GO:0044444_(0.27)_cytoplasmic_part GO:0044425_(0.27)_membrane_part GO:0032991_(0.27)_macromolecular_complex GO:0031012_(0.27)_extracellular_matrix GO:0005886_(0.27)_plasma_membrane | UniProt annotation score: ◉◉○○○ | ||
48 | >NX_Q969W3-1|F104A_HUMAN FAM104A GN=FAM104A MGGRGADAGSSGGTGPTEGYSPPAASTRAAARAKARGGGRGGRRNTTPSV PSLRGAAPRSFHPPAAMSERLRPRKRRRNGNEEDNHLPPQTKRSSRNPVF QDSWDTESSGSDSGGSSSSSSSSINSPDRASGPEGSLSQTMAGSSPNTPQ PVPEQSALCQGLYFHINQTLREAHFHSLQHRGRPLT chromosome location: 73207353-73236753 (17q25.1) Database cross references: | MF: GO:0042802_(0.13)_identical_protein_binding GO:0005086_(0.13)_ARF_guanyl-nucleotide_exchange factor_activity GO:0035091_(0.07)_phosphatidylinositol_binding GO:0034987_(0.07)_immunoglobulin_receptor_binding GO:0008017_(0.07)_microtubule_binding GO:0005524_(0.07)_ATP_binding GO:0005096_(0.07)_GTPase_activator_activity GO:0004715_(0.07)_non-membrane_spanning_protein tyrosine_kinase_activity BP: GO:0044260_(0.81)_cellular_macromolecule_metabolic process GO:0044238_(0.81)_primary_metabolic_process GO:0006950_(0.81)_response_to_stress GO:0042276_(0.80)_error-prone_translesion synthesis GO:0043547_(0.11)_positive_regulation_of_GTPase activity GO:0006897_(0.11)_endocytosis GO:2000251_(0.06)_positive_regulation_of_actin cytoskeleton_reorganization GO:2000145_(0.06)_regulation_of_cell_motility GO:0090339_(0.06)_negative_regulation_of_formin- nucleated_actin_cable_assembly GO:0051297_(0.06)_centrosome_organization GO:0051056_(0.06)_regulation_of_small_GTPase mediated_signal_transduction GO:0045639_(0.06)_positive_regulation_of_myeloid cell_differentiation GO:0045087_(0.06)_innate_immune_response GO:0043304_(0.06)_regulation_of_mast_cell degranulation GO:0042127_(0.06)_regulation_of_cell_proliferation CC: GO:0044464_(1.00)_cell_part GO:0043229_(0.98)_intracellular_organelle GO:0043231_(0.96)_intracellular_membrane-bounded organelle GO:0044446_(0.90)_intracellular_organelle_part GO:0032991_(0.86)_macromolecular_complex GO:0043234_(0.85)_protein_complex GO:0005634_(0.84)_nucleus GO:0044444_(0.82)_cytoplasmic_part GO:0061695_(0.81)_transferase_complex, transferring_phosphorus-containing_groups GO:0016035_(0.80)_zeta_DNA_polymerase_complex GO:0005829_(0.68)_cytosol GO:0044425_(0.63)_membrane_part GO:0016020_(0.57)_membrane GO:0005737_(0.57)_cytoplasm GO:0031982_(0.51)_vesicle | UniProt annotation: GO:0005515_protein_binding UniProt annotation score: ◉◉○○○ NextProt annotation: GO:0005515_protein_binding | ||
49 | >NX_Q9BSJ5-1|CQ080_HUMAN Uncharacterized protein C17orf80 GN=C17orf80 MSDNPPRMEVCPYCKKPFKRLKSHLPYCKMIGPTIPTDQKVYQSKPATLP RAKKMKGPIKDLIKAKGKELETENEERNSKLVVDKPEQTVKTFPLPAVGL ERAATTKADKDIKNPIQPSFKMLKNTKPMTTFQEETKAQFYASEKTSPKR ELAKDLPKSGESRCNPSEAGASLLVGSIEPSLSNQDRKYSSTLPNDVQTT SGDLKLDKIDPQRQELLVKLLDVPTGDCHISPKNVSDGVKRVRTLLSNER DSKGRDHLSGVPTDVTVTETPEKNTESLILSLKMSSLGKIQVMEKQEKGL TLGVETCGSKGNAEKSMSATEKQERTVMSHGCENFNTRDSVTGKESQGER PHLSLFIPRETTYQFHSVSQSSSQSLASLATTFLQEKKAEAQNHHCVPDV KALMESPEGQLSLEPKSDSQFQASHTGCQSPLCSAQRHTPQSPFTNHAAA AGRKTLRSCMGLEWFPELYPGYLGLGVLPGKPQCWNAMTQKPQLISPQGE RLSQVSLLERSSTHIRSLEPPAGLTTSNFSLMRLLGAVQKGWIRCNTTIR KSGFGGITMLFTGYFVLCCSWSFRRLKKLCRPLPWKSTVPPCIGVAKTTG DCRSKTCLD chromosome location: 73232233-73248947 (17q25.1) Database cross references: | MF: GO:1901363_(0.43)_heterocyclic_compound_binding GO:0097159_(0.43)_organic_cyclic_compound_binding GO:0097367_(0.40)_carbohydrate_derivative_binding GO:0035639_(0.39)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.39)_adenyl_ribonucleotide_binding GO:0032550_(0.39)_purine_ribonucleoside_binding GO:0008092_(0.35)_cytoskeletal_protein_binding GO:0003676_(0.35)_nucleic_acid_binding GO:0003824_(0.34)_catalytic_activity GO:0043169_(0.30)_cation_binding GO:0005198_(0.20)_structural_molecule_activity GO:0005201_(0.16)_extracellular_matrix_structural constituent GO:0030674_(0.14)_protein_binding,_bridging GO:0030507_(0.12)_spectrin_binding GO:0008093_(0.12)_cytoskeletal_adaptor_activity BP: GO:0009987_(0.71)_cellular_process GO:0044699_(0.64)_single-organism_process GO:0065007_(0.63)_biological_regulation GO:0044763_(0.62)_single-organism_cellular_process GO:0032501_(0.47)_multicellular_organismal_process GO:0044767_(0.46)_single-organism_developmental process GO:0016043_(0.46)_cellular_component_organization GO:0065008_(0.44)_regulation_of_biological_quality GO:0050794_(0.42)_regulation_of_cellular_process GO:0044707_(0.37)_single-multicellular_organism process GO:0006996_(0.33)_organelle_organization GO:0051239_(0.30)_regulation_of_multicellular organismal_process GO:0023051_(0.29)_regulation_of_signaling GO:0010646_(0.29)_regulation_of_cell_communication GO:0003008_(0.29)_system_process CC: GO:0070062_(0.97)_extracellular_exosome GO:0005753_(0.03)_mitochondrial_proton- transporting_ATP_synthase_complex | UniProt annotation: GO:0070062_extracellular_exosome GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ | ||
50 | >NX_Q7RTS6-1|OTOP2_HUMAN Otopetrin-2 GN=OTOP2 MSEELAQGPKESPPAPRAGPREVWKKGGRLLSVLLAVNVLLLACTLISGG AFNKVAVYDTDVFALLTAMMLLATLWILFYLLRTVRCPCAVPYRDAHAGP IWLRGGLVLFGICTLIMDVFKTGYYSSFFECQSAIKILHPLIQAVFVIIQ TYFLWVSAKDCVHVHLDLTWCGLMFTLTTNLAIWMAAVVDESVHQSHSYS SSHSNASHARLISDQHADNPVGGDSCLCSTAVCQIFQQGYFYLYPFNIEY SLFASTMLYVMWKNVGRFLASTPGHSHTPTPVSLFRETFFAGPVLGLLLF VVGLAVFIIYEVQVSGDGSRTRQALVIYYSFNIVCLGLTTLVSLSGSIIY RFDRRAMDHHKNPTRTLDVALLMGAALGQYAISYYSIVAVVAGTPQDLLA GLNLTHALLMIAQHTFQNMFIIESLHRGPPGAEPHSTHPKEPCQDLTFTN LDALHTLSACPPNPGLVSPSPSDQREAVAIVSTPRSQWRRQCLKDISLFL LLCNVILWIMPAFGARPHFSNTVEVDFYGYSLWAVIVNICLPFGIFYRMH AVSSLLEVYVLS chromosome location: 74924275-74933912 (17q25.1) Database cross references: | MF: GO:0046983_(0.55)_protein_dimerization_activity GO:0046873_(0.55)_metal_ion_transmembrane transporter_activity GO:0042802_(0.55)_identical_protein_binding GO:0031420_(0.55)_alkali_metal_ion_binding GO:0015077_(0.55)_monovalent_inorganic_cation transmembrane_transporter_activity GO:0009678_(0.39)_hydrogen-translocating pyrophosphatase_activity GO:0004427_(0.39)_inorganic_diphosphatase_activity BP: GO:0042472_(1.00)_inner_ear_morphogenesis GO:0009590_(0.51)_detection_of_gravity GO:0045299_(0.49)_otolith_mineralization GO:0032475_(0.49)_otolith_formation GO:0098662_(0.41)_inorganic_cation_transmembrane transport GO:0030001_(0.41)_metal_ion_transport GO:0015992_(0.28)_proton_transport CC: GO:0016020_(0.86)_membrane GO:0044464_(0.72)_cell_part GO:0016021_(0.61)_integral_component_of_membrane GO:0032991_(0.35)_macromolecular_complex GO:0005886_(0.35)_plasma_membrane GO:0044424_(0.31)_intracellular_part GO:0043234_(0.31)_protein_complex GO:1902494_(0.27)_catalytic_complex GO:0005737_(0.24)_cytoplasm GO:0044459_(0.20)_plasma_membrane_part GO:0009380_(0.20)_excinuclease_repair_complex GO:0044444_(0.13)_cytoplasmic_part GO:0098797_(0.10)_plasma_membrane_protein_complex GO:0070469_(0.10)_respiratory_chain GO:0043226_(0.10)_organelle | UniProt annotation: Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. {ECO:0000250|UniProtKB:Q80SX5}. GO:1902600_proton_transmembrane_transport GO:0015252_proton_channel_activity GO:0005886_plasma_membrane GO:0016020_membrane GO:0006811_ion_transport GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ | ||
51 | >NX_Q86X02-1|CDR2L_HUMAN Cerebellar degeneration-related protein 2-like GN=CDR2L MRRAAGMEDFSAEEEESWYDQQDLEQDLHLAAELGKTLLERNKELEGSLQ QMYSTNEEQVQEIEYLTKQLDTLRHVNEQHAKVYEQLDLTARDLELTNHR LVLESKAAQQKIHGLTETIERLQAQVEELQAQVEQLRGLEQLRVLREKRE RRRTIHTFPCLKELCTSPRCKDAFRLHSSSLELGPRPLEQENERLQTLVG ALRSQVSQERQRKERAEREYTAVLQEYSELERQLCEMEACRLRVQELEAE LLELQQMKQAKTYLLGPDDHLAEALLAPLTQAPEADDPQPGRGDDLGAQD GVSSPAASPGHVVRKSCSDTALNAIVAKDPASRHAGNLTLHANSVRKRGM SILREVDEQYHALLEKYEELLSKCRQHGAGVRHAGVQTSRPISRDSSWRD LRGGEEGQGEVKAGEKSLSQHVEAVDKRLEQSQPEYKALFKEIFSRIQKT KADINATKVKTHSSK chromosome location: 74987632-75005800 (17q25.1) Database cross references: | MF: GO:0003824_(0.49)_catalytic_activity GO:0016787_(0.46)_hydrolase_activity GO:0017111_(0.45)_nucleoside-triphosphatase activity GO:0008092_(0.37)_cytoskeletal_protein_binding GO:1901363_(0.35)_heterocyclic_compound_binding GO:0097159_(0.35)_organic_cyclic_compound_binding GO:0035639_(0.33)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.33)_adenyl_ribonucleotide_binding GO:0032550_(0.33)_purine_ribonucleoside_binding GO:0016887_(0.19)_ATPase_activity GO:0003774_(0.19)_motor_activity GO:0003777_(0.16)_microtubule_motor_activity GO:0019899_(0.07)_enzyme_binding GO:0016740_(0.05)_transferase_activity GO:0008574_(0.05)_ATP-dependent_microtubule_motor activity,_plus-end-directed BP: GO:0009987_(0.90)_cellular_process GO:0044699_(0.83)_single-organism_process GO:0044763_(0.80)_single-organism_cellular_process GO:0016043_(0.52)_cellular_component_organization GO:0006996_(0.44)_organelle_organization GO:0022607_(0.37)_cellular_component_assembly GO:0007010_(0.36)_cytoskeleton_organization GO:0070925_(0.33)_organelle_assembly GO:0043933_(0.31)_macromolecular_complex_subunit organization GO:0043623_(0.30)_cellular_protein_complex assembly GO:0065007_(0.29)_biological_regulation GO:0031106_(0.28)_septin_ring_organization GO:0050789_(0.27)_regulation_of_biological_process GO:0007017_(0.27)_microtubule-based_process GO:0051179_(0.26)_localization CC: GO:0044464_(1.00)_cell_part GO:0044424_(0.99)_intracellular_part GO:0044446_(0.89)_intracellular_organelle_part GO:0044430_(0.87)_cytoskeletal_part GO:0043226_(0.87)_organelle GO:0043229_(0.86)_intracellular_organelle GO:0044444_(0.85)_cytoplasmic_part GO:0005737_(0.80)_cytoplasm GO:0032991_(0.65)_macromolecular_complex GO:0043234_(0.64)_protein_complex GO:0043232_(0.61)_intracellular_non-membrane- bounded_organelle GO:0016459_(0.54)_myosin_complex GO:0016020_(0.49)_membrane GO:0043227_(0.41)_membrane-bounded_organelle GO:0043231_(0.40)_intracellular_membrane-bounded organelle | UniProt annotation: GO:0005515_protein_binding UniProt annotation score: ◉◉◉○○ NextProt annotation: GO:0005515_protein_binding | High: cells) epithelial_cells) nerve/ganglion) germinal_center_cells) Langerhans) melanocytes) | |
52 | >NX_Q12767-1|TMM94_HUMAN Transmembrane protein 94 GN=TMEM94 MDLKEKHLGEPPSALGLSTRKALSVLKEQLEAVLEGHLRERKKCLTWKEV WRSSFLHHSNRCSCFHWPGASLMLLAVLLLLGCCGGQPAGSRGVGLVNAS ALFLLLLLNLVLIGRQDRLKRREVERRLRGIIDQIQDALRDGREIQWPSA MYPDLHMPFAPSWSLHWAYRDGHLVNLPVSLLVEGDIIALRPGQESFASL RGIKDDEHIVLEPGDLFPPFSPPPSPRGEVERGPQSPQQHRLFRVLETPV IDNIRWCLDMALSRPVTALDNERFTVQSVMLHYAVPVVLAGFLITNALRF IFSAPGVTSWQYTLLQLQVNGVLPILPLLFPVLWVLATACGEARVLAQMS KASPSSLLAKFSEDTLSSYTEAVSSQEMLRCIWGHFLRVLGGTSPTLSHS SSLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPPHSSHEDLT DGLSTRSFCHPEPHERDALLAGSLNNTLHLSNEQERGDWPGEAPKPPEPY SHHKAHGRSKHPSGSNVSFSRDTEGGEEEPSKTQPGMESDPYEAEDFVCD YHLEMLSLSQDQQNPSCIQFDDSNWQLHLTSLKPLGLNVLLNLCDASVTE RLCRFSDHLCNIALQESHSAVLPVHVPWGLCELARLIGFTPGAKELFKQE NHLALYRLPSAETMKETSLGRLSCVTKRRPPLSHMISLFIKDTTTSTEQM LSHGTADVVLEACTDFWDGADIYPLSGSDRKKVLDFYQRACLSGYCSAFA YKPMNCALSSQLNGKCIELVQVPGQSSIFTMCELPSTIPIKQNARRSSWS SDEGIGEVLEKEDCMQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIR FVYFSLEDELKSKVFAEKMGLETGWNCHISLTPNGDMPGSEIPPSSPSHA GSLHDDLNQVSRDDAEGLLLMEEEGHSDLISFQPTDSDIPSFLEDSNRAK LPRGIHQVRPHLQNIDNVPLLVPLFTDCTPETMCEMIKIMQEYGEVTCCL GSSANLRNSCLFLQSDISIALDPLYPSRCSWETFGYATSISMAQASDGLS PLQLSGQLNSLPCSLTFRQEETISIIRLIEQARHATYGIRKCFLFLLQCQ LTLVVIQFLSCLVQLPPLLSTTDILWLSCFCYPLLSISLLGKPPHSSIMS MATGKNLQSIPKKTQHYFLLCFLLKFSLTISSCLICFGFTLQSFCDSSRD RNLTNCSSVMLPSNDDRAPAWFEDFANGLLSAQKLTAALIVLHTVFISIT HVHRTKPLWRKSPLTNLWWAVTVPVVLLGQVVQTAVDLQLWTHRDSHVHF GLEDVPLLTWLLGCLSLVLVVVTNEIVKLHEIRVRVRYQKRQKLQFETKL GMNSPF chromosome location: 75441159-75500090 (17q25.1) Database cross references: | MF: GO:0043492_(0.91)_ATPase_activity,_coupled_to movement_of_substances GO:0022892_(0.91)_substrate-specific_transporter activity GO:0019829_(0.74)_cation-transporting_ATPase activity GO:0022890_(0.61)_inorganic_cation_transmembrane transporter_activity GO:0015662_(0.61)_ATPase_activity,_coupled_to transmembrane_movement_of_ions,_phosphorylative mechanism GO:0046873_(0.57)_metal_ion_transmembrane transporter_activity GO:0015077_(0.41)_monovalent_inorganic_cation transmembrane_transporter_activity GO:0005524_(0.37)_ATP_binding GO:0005391_(0.37)_sodium:potassium-exchanging ATPase_activity GO:0046872_(0.29)_metal_ion_binding GO:0031420_(0.28)_alkali_metal_ion_binding GO:0019899_(0.28)_enzyme_binding GO:0072509_(0.24)_divalent_inorganic_cation transmembrane_transporter_activity GO:0004012_(0.24)_phospholipid-translocating ATPase_activity GO:0005388_(0.23)_calcium-transporting_ATPase activity BP: GO:0009987_(0.90)_cellular_process GO:0044699_(0.85)_single-organism_process GO:0044763_(0.84)_single-organism_cellular_process GO:0065007_(0.81)_biological_regulation GO:0065008_(0.80)_regulation_of_biological_quality GO:0098771_(0.77)_inorganic_ion_homeostasis GO:0030003_(0.77)_cellular_cation_homeostasis GO:0006875_(0.72)_cellular_metal_ion_homeostasis GO:0006810_(0.71)_transport GO:0006812_(0.68)_cation_transport GO:0034220_(0.66)_ion_transmembrane_transport GO:0098662_(0.65)_inorganic_cation_transmembrane transport GO:1902600_(0.64)_hydrogen_ion_transmembrane transport GO:0090662_(0.60)_ATP_hydrolysis_coupled transmembrane_transport GO:0015988_(0.60)_energy_coupled_proton transmembrane_transport,_against_electrochemical gradient CC: GO:0005654_(1.00)_nucleoplasm | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ | High: epithelial_cells) | |
53 | >NX_Q8WXE0-1|CSKI2_HUMAN Caskin-2 GN=CASKIN2 MGREQDLILAVKNGDVTGVQKLVAKVKATKTKLLGSTKRLNVNYQDADGF SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRL LLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKT PLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNG HREVIRQLLRAGIEINRQTKTGTALHEAALYGKTEVVRLLLEGGVDVNIR NTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDFWNLHDPTA LNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVG IPAARLPSAPTPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGD RNSVGSEGSVGSIRSAGSGQSSEGTNGHGPGLLIENAQPLPSAGEDQVLP GLHPPSLADNLSHRPLANCRSGEQIFTQDVRPEQLLEGKDAQAIHNWLSE FQLEGYTAHFLQAGYDVPTISRMTPEDLTAIGVTKPGHRKKIASEIAQLS IAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLTWEELQE IGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEG LENGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQES IGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQG PPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHS LSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPA RGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGAT GPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGL PFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCRERE PLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVP TPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGT APKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQAQQRLEQ TSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTMFDALADQLDAM LD chromosome location: 75500261-75515583 (17q25.1) Database cross references: | MF: GO:0003824_(0.44)_catalytic_activity GO:0016740_(0.39)_transferase_activity GO:0019899_(0.31)_enzyme_binding GO:0004842_(0.25)_ubiquitin-protein_transferase activity GO:0008092_(0.21)_cytoskeletal_protein_binding GO:1901363_(0.18)_heterocyclic_compound_binding GO:0097159_(0.18)_organic_cyclic_compound_binding GO:0031625_(0.18)_ubiquitin_protein_ligase_binding GO:0030507_(0.15)_spectrin_binding GO:0008093_(0.15)_cytoskeletal_adaptor_activity GO:0016773_(0.14)_phosphotransferase_activity, alcohol_group_as_acceptor GO:0016301_(0.14)_kinase_activity GO:0005215_(0.14)_transporter_activity GO:0003676_(0.14)_nucleic_acid_binding GO:0008324_(0.13)_cation_transmembrane_transporter activity BP: GO:0065007_(0.71)_biological_regulation GO:0050789_(0.66)_regulation_of_biological_process GO:0050794_(0.65)_regulation_of_cellular_process GO:0009987_(0.42)_cellular_process GO:0007165_(0.41)_signal_transduction GO:0044699_(0.36)_single-organism_process GO:0044763_(0.27)_single-organism_cellular_process GO:0016043_(0.24)_cellular_component_organization GO:0080090_(0.18)_regulation_of_primary_metabolic process GO:0060255_(0.18)_regulation_of_macromolecule metabolic_process GO:0051179_(0.18)_localization GO:0044767_(0.18)_single-organism_developmental process GO:0044237_(0.17)_cellular_metabolic_process GO:0031323_(0.17)_regulation_of_cellular_metabolic process GO:0071704_(0.16)_organic_substance_metabolic process CC: GO:0044464_(0.92)_cell_part GO:0044424_(0.84)_intracellular_part GO:0005737_(0.60)_cytoplasm GO:0043226_(0.46)_organelle GO:0043229_(0.45)_intracellular_organelle GO:0043231_(0.41)_intracellular_membrane-bounded organelle GO:0005634_(0.36)_nucleus GO:0032991_(0.26)_macromolecular_complex GO:0043234_(0.24)_protein_complex GO:1902494_(0.19)_catalytic_complex GO:0044444_(0.19)_cytoplasmic_part GO:0016020_(0.18)_membrane GO:0000151_(0.18)_ubiquitin_ligase_complex GO:0044422_(0.16)_organelle_part GO:0044446_(0.12)_intracellular_organelle_part | UniProt annotation: GO:0016020_membrane GO:0005737_cytoplasm UniProt annotation score: ◉◉◉○○ | High: peripheral_nerve/ganglion) cells) molecular_layer;_Purkinje_cells) germinal_center_cells) center_cells;_squamous_epithelial_cells) | |
54 | >NX_Q71RC9-1|SMIM5_HUMAN Small integral membrane protein 5 GN=SMIM5 MAATDFVQEMRAVGERLLLKLQRLPQAEPVEIVAFSVIILFTATVLLLLL IACSCCCTHCCCPERRGRKVQVQPTPP chromosome location: 75633434-75641404 (17q25.1) Database cross references: | MF: GO:0051015_(0.33)_actin_filament_binding GO:0030274_(0.33)_LIM_domain_binding GO:0017166_(0.33)_vinculin_binding GO:0005200_(0.33)_structural_constituent_of cytoskeleton GO:0005178_(0.33)_integrin_binding BP: GO:0098876_(0.48)_vesicle-mediated_transport_to the_plasma_membrane GO:0071702_(0.48)_organic_substance_transport GO:0051278_(0.48)_fungal-type_cell_wall polysaccharide_biosynthetic_process GO:0045184_(0.48)_establishment_of_protein localization GO:0030010_(0.48)_establishment_of_cell_polarity GO:0006892_(0.48)_post-Golgi_vesicle-mediated transport GO:0006038_(0.48)_cell_wall_chitin_biosynthetic process GO:0000281_(0.48)_mitotic_cytokinesis GO:0070527_(0.33)_platelet_aggregation GO:0030866_(0.33)_cortical_actin_cytoskeleton organization GO:0007044_(0.33)_cell-substrate_junction_assembly GO:0007016_(0.33)_cytoskeletal_anchoring_at_plasma membrane CC: GO:0044424_(1.00)_intracellular_part GO:0044446_(0.93)_intracellular_organelle_part GO:0043229_(0.93)_intracellular_organelle GO:0043227_(0.93)_membrane-bounded_organelle GO:0016020_(0.93)_membrane GO:0044444_(0.60)_cytoplasmic_part GO:0043234_(0.60)_protein_complex GO:0044431_(0.53)_Golgi_apparatus_part GO:0044425_(0.53)_membrane_part GO:0005794_(0.53)_Golgi_apparatus GO:0031988_(0.47)_membrane-bounded_vesicle GO:0005737_(0.47)_cytoplasm GO:0070062_(0.40)_extracellular_exosome GO:0044430_(0.40)_cytoskeletal_part GO:0034044_(0.40)_exomer_complex | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ | High: cells) center_cells;_squamous_epithelial_cells) glandular_cells) glandular_cells) Langerhans) cells;_neuronal_cells) germinal_center_cells) epithelial_cells) molecular_layer;_Purkinje_cells) pulp) | |
55 | >NX_Q96LD4-1|TRI47_HUMAN Tripartite motif-containing protein 47 GN=TRIM47 MDGSGPFSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGG AARCPLCQEPFPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPS APSALPSVPEPSAPCAPEPWPAGEEPVRCDACPEGAALPAALSCLSCLAS FCPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLRPLERYCRAERVCL CEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSR RTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRS QGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPG PGPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSE ADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKGVK RVLCPINYPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGWVSMGVMAE DFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVGV CLEYADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSH FAGLFTHRLKPAFFLESVDAHLQIGPLKKSCISVLKRR chromosome location: 75874161-75878575 (17q25.1) Database cross references: | MF: GO:0003824_(0.79)_catalytic_activity GO:0004842_(0.76)_ubiquitin-protein_transferase activity GO:0061630_(0.31)_ubiquitin_protein_ligase activity GO:0046872_(0.21)_metal_ion_binding GO:0004871_(0.21)_signal_transducer_activity GO:0004872_(0.20)_receptor_activity GO:0008329_(0.19)_signaling_pattern_recognition receptor_activity GO:0008270_(0.19)_zinc_ion_binding GO:0042802_(0.16)_identical_protein_binding GO:0019899_(0.14)_enzyme_binding GO:0016787_(0.14)_hydrolase_activity GO:0042803_(0.12)_protein_homodimerization activity GO:0005102_(0.12)_receptor_binding GO:0050827_(0.11)_toxin_receptor_binding GO:0004222_(0.11)_metalloendopeptidase_activity BP: GO:0009987_(0.85)_cellular_process GO:0065007_(0.84)_biological_regulation GO:0050789_(0.69)_regulation_of_biological_process GO:0050794_(0.66)_regulation_of_cellular_process GO:0071704_(0.60)_organic_substance_metabolic process GO:0044238_(0.60)_primary_metabolic_process GO:0044260_(0.59)_cellular_macromolecule_metabolic process GO:0031323_(0.54)_regulation_of_cellular_metabolic process GO:0019538_(0.54)_protein_metabolic_process GO:0060255_(0.53)_regulation_of_macromolecule metabolic_process GO:0080090_(0.52)_regulation_of_primary_metabolic process GO:0048518_(0.50)_positive_regulation_of biological_process GO:0006464_(0.50)_cellular_protein_modification process GO:0032446_(0.48)_protein_modification_by_small protein_conjugation GO:0048522_(0.47)_positive_regulation_of_cellular process CC: GO:0044464_(0.99)_cell_part GO:0044424_(0.97)_intracellular_part GO:0043226_(0.63)_organelle GO:0043229_(0.59)_intracellular_organelle GO:0005737_(0.57)_cytoplasm GO:0043227_(0.52)_membrane-bounded_organelle GO:0044444_(0.51)_cytoplasmic_part GO:0044422_(0.51)_organelle_part GO:0044446_(0.50)_intracellular_organelle_part GO:0032991_(0.49)_macromolecular_complex GO:0043231_(0.46)_intracellular_membrane-bounded organelle GO:0016020_(0.41)_membrane GO:0005634_(0.41)_nucleus GO:0005576_(0.41)_extracellular_region GO:0043232_(0.38)_intracellular_non-membrane- bounded_organelle | UniProt annotation: GO:0005829_cytosol GO:0008270_zinc_ion_binding GO:0005622_intracellular GO:0046872_metal_ion_binding GO:0005737_cytoplasm GO:0005634_nucleus UniProt annotation score: ◉◉◉◉○ NextProt annotation: GO:0008270_zinc_ion_binding | ||
56 | >NX_Q8IYN6-1|UBAD2_HUMAN UBA-like domain-containing protein 2 GN=UBALD2 MSVNMDELRHQVMINQFVLAAGCAADQAKQLLQAAHWQFETALSTFFQET NIPNSHHHHQMMCTPSNTPATPPNFPDALAMFSKLRASEGLQSSNSPMTA AACSPPANFSPFWASSPPSHQAPWIPPSSPTTFHHLHRPQPTWPPGAQQG GAQQKAMAAMDGQR chromosome location: 76265202-76271299 (17q25.1) Database cross references: | MF: GO:0003824_(0.65)_catalytic_activity GO:1901363_(0.46)_heterocyclic_compound_binding GO:0097159_(0.46)_organic_cyclic_compound_binding GO:0043169_(0.41)_cation_binding GO:0016491_(0.40)_oxidoreductase_activity GO:0046906_(0.39)_tetrapyrrole_binding GO:0016684_(0.39)_oxidoreductase_activity,_acting on_peroxide_as_acceptor GO:0016209_(0.39)_antioxidant_activity GO:0016772_(0.28)_transferase_activity, transferring_phosphorus-containing_groups GO:0016779_(0.26)_nucleotidyltransferase_activity GO:0001055_(0.25)_RNA_polymerase_II_activity GO:0016787_(0.12)_hydrolase_activity GO:0003676_(0.11)_nucleic_acid_binding GO:0001104_(0.11)_RNA_polymerase_II_transcription cofactor_activity GO:0003723_(0.09)_RNA_binding BP: GO:0009987_(0.81)_cellular_process GO:0044699_(0.73)_single-organism_process GO:0008152_(0.64)_metabolic_process GO:0044237_(0.62)_cellular_metabolic_process GO:0044248_(0.53)_cellular_catabolic_process GO:0044763_(0.49)_single-organism_cellular_process GO:0050896_(0.44)_response_to_stimulus GO:0065007_(0.43)_biological_regulation GO:0044710_(0.41)_single-organism_metabolic process GO:0006950_(0.41)_response_to_stress GO:1990748_(0.39)_cellular_detoxification GO:0050794_(0.39)_regulation_of_cellular_process GO:0044238_(0.39)_primary_metabolic_process GO:0043170_(0.39)_macromolecule_metabolic_process GO:0042743_(0.39)_hydrogen_peroxide_metabolic process CC: GO:0044464_(0.99)_cell_part GO:0044424_(0.96)_intracellular_part GO:0043226_(0.73)_organelle GO:0043227_(0.71)_membrane-bounded_organelle GO:0043229_(0.70)_intracellular_organelle GO:0043231_(0.67)_intracellular_membrane-bounded organelle GO:0044444_(0.64)_cytoplasmic_part GO:0044422_(0.62)_organelle_part GO:0044446_(0.61)_intracellular_organelle_part GO:0005576_(0.55)_extracellular_region GO:0032991_(0.46)_macromolecular_complex GO:0043234_(0.44)_protein_complex GO:0005634_(0.43)_nucleus GO:0044428_(0.42)_nuclear_part GO:0044451_(0.36)_nucleoplasm_part | UniProt annotation score: ◉◉○○○ | ||
57 | >NX_Q9H0J4-1|QRIC2_HUMAN Glutamine-rich protein 2 GN=QRICH2 MKDAAEELSFARVLLQRVDELEKLFKDREQFLELVSRKLSLVPGAEEVTM VTWEELEQAITDGWRASQAGSETLMGFSKHGGFTSLTSPEGTLSGDSTKQ PSIEQALDSASGLGPDRTASGSGGTAHPSDGVSSREQSKVPSGTGRQQQP RARDEAGVPRLHQSSTFQFKSDSDRHRSREKLTSTQPRRNARPGPVQQDL PLARDQPSSVPASQSQVHLRPDRRGLEPTGMNQPGLVPASTYPHGVVPLS MGQLGVPPPEMDDRELIPFVVDEQRMLPPSVPGRDQQGLELPSTDQHGLV SVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQGLVPPGIDQQGLT LPVVDQHGLVLPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPGTE QHDLIQSGRFQRALVQRGAYQPGLVQPGADQRGLVRPGMDQSGLAQPGAD QRGLVWPGMDQSGLAQPGRDQHGLIQPGTGQHDLVQSGTGQGVLVQPGVD QPGMVQPGRFQRALVQPGAYQPGLVQPGADQIDVVQPGADQHGLVQSGAD QSDLAQPGAVQHGLVQPGVDQRGLAQPRADHQRGLVPPGADQRGLVQPGA DQHGLVQPGVDQHGLAQPGEVQRSLVQPGIVQRGLVQPGAVQRGLVQPGA VQRGLVQPGVDQRGLVQPGAVQRGLVQPGAVQHGLVQPGADQRGLVQPGV DQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQPGAGQLGMVQPGI GQQGMVQPQADPHGLVQPGAYPLGLVQPGAYLHDLSQSGTYPRGLVQPGM DQYGLRQPGAYQPGLIAPGTKLRGSSTFQADSTGFISVRPYQHGMVPPGR EQYGQVSPLLASQGLASPGIDRRSLVPPETYQQGLMHPGTDQHSPIPLST GLGSTHPDQQHVASPGPGEHDQVYPDAAQHGHAFSLFDSHDSMYPGYRGP GYLSADQHGQEGLDPNRTRASDRHGIPAQKAPGQDVTLFRSPDSVDRVLS EGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKD LDEEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAK VERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQ DRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAH TLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKA KLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQ GLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQFDATTEQLNHMMQE LVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDPVKQLLEDRWKSLRQQL RERPPLYQADEAAAMRRQLLAHFHCLSCDRPLETPVTGHAIPVTPAGPGL PGHHSIRPYTVFELEQVRQHSRNLKLGSAFPRGDLAQMEQSVGRLRSMHS KMLMNIEKVQIHFGGSTKASSQIIRELLHAQCLGSPCYKRVTDMADYTYS TVPRRCGGSHTLTYPYHRSRPQHLPRGLYPTEEIQIAMKHDEVDILGLDG HIYKGRMDTRLPGILRKDSSGTSKRKSQQPRPHVHRPPSLSSNGQLPSRP QSAQISAGNTSER chromosome location: 76274049-76307998 (17q25.1) Database cross references: | MF: GO:0003824_(0.38)_catalytic_activity GO:0016787_(0.29)_hydrolase_activity GO:0017111_(0.26)_nucleoside-triphosphatase activity GO:0016887_(0.25)_ATPase_activity GO:0003774_(0.23)_motor_activity GO:0003777_(0.21)_microtubule_motor_activity GO:0008092_(0.15)_cytoskeletal_protein_binding GO:1901363_(0.12)_heterocyclic_compound_binding GO:0097159_(0.12)_organic_cyclic_compound_binding GO:0019899_(0.11)_enzyme_binding GO:0016740_(0.11)_transferase_activity GO:0003676_(0.11)_nucleic_acid_binding GO:0015631_(0.08)_tubulin_binding GO:0005198_(0.08)_structural_molecule_activity GO:0016301_(0.07)_kinase_activity BP: GO:0009987_(0.79)_cellular_process GO:0044699_(0.64)_single-organism_process GO:0044763_(0.57)_single-organism_cellular_process GO:0016043_(0.43)_cellular_component_organization GO:0065007_(0.36)_biological_regulation GO:0050789_(0.33)_regulation_of_biological_process GO:0050794_(0.31)_regulation_of_cellular_process GO:0006996_(0.31)_organelle_organization GO:0007017_(0.30)_microtubule-based_process GO:0051179_(0.29)_localization GO:0006928_(0.29)_movement_of_cell_or_subcellular component GO:0032502_(0.28)_developmental_process GO:0044767_(0.27)_single-organism_developmental process GO:0051234_(0.26)_establishment_of_localization GO:0051641_(0.22)_cellular_localization CC: GO:0044464_(0.92)_cell_part GO:0044424_(0.87)_intracellular_part GO:0044422_(0.61)_organelle_part GO:0044446_(0.59)_intracellular_organelle_part GO:0043226_(0.45)_organelle GO:0043229_(0.42)_intracellular_organelle GO:0044430_(0.40)_cytoskeletal_part GO:0032991_(0.39)_macromolecular_complex GO:0044444_(0.36)_cytoplasmic_part GO:0043234_(0.36)_protein_complex GO:0043227_(0.26)_membrane-bounded_organelle GO:0043232_(0.24)_intracellular_non-membrane- bounded_organelle GO:0043231_(0.23)_intracellular_membrane-bounded organelle GO:0005737_(0.20)_cytoplasm GO:0044428_(0.17)_nuclear_part | UniProt annotation score: ◉◉◉○○ | High: | |
58 | >NX_P84157-1|MXRA7_HUMAN Matrix-remodeling-associated protein 7 GN=MXRA7 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEA TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAA APAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRG NQYKKMMTKEELEEEQRVQKEQLAAIFKLMKDNKETFGEMSDGDVQEQLR LYDM chromosome location: 76672551-76711016 (17q25.1) Database cross references: | MF: GO:0003676_(0.40)_nucleic_acid_binding GO:0005198_(0.29)_structural_molecule_activity GO:0003824_(0.21)_catalytic_activity GO:0003700_(0.12)_transcription_factor_activity, sequence-specific_DNA_binding GO:0003677_(0.12)_DNA_binding GO:0097157_(0.10)_pre-mRNA_intronic_binding GO:0030623_(0.10)_U5_snRNA_binding GO:0030620_(0.10)_U2_snRNA_binding GO:0030619_(0.10)_U1_snRNA_binding GO:0017070_(0.10)_U6_snRNA_binding GO:0000386_(0.10)_second_spliceosomal transesterification_activity GO:0005543_(0.09)_phospholipid_binding GO:0008324_(0.08)_cation_transmembrane_transporter activity GO:0004702_(0.07)_receptor_signaling_protein serine/threonine_kinase_activity GO:0016787_(0.06)_hydrolase_activity BP: GO:0009987_(0.84)_cellular_process GO:0050896_(0.43)_response_to_stimulus GO:0051716_(0.37)_cellular_response_to_stimulus GO:0006950_(0.31)_response_to_stress GO:0044699_(0.30)_single-organism_process GO:0044238_(0.30)_primary_metabolic_process GO:0043170_(0.30)_macromolecule_metabolic_process GO:0016043_(0.29)_cellular_component_organization GO:0090304_(0.28)_nucleic_acid_metabolic_process GO:0044260_(0.28)_cellular_macromolecule_metabolic process GO:0044763_(0.27)_single-organism_cellular_process GO:0016070_(0.25)_RNA_metabolic_process GO:0006979_(0.24)_response_to_oxidative_stress GO:0065007_(0.23)_biological_regulation GO:0071470_(0.22)_cellular_response_to_osmotic stress CC: GO:0044464_(0.99)_cell_part GO:0044424_(0.85)_intracellular_part GO:0043227_(0.71)_membrane-bounded_organelle GO:0043229_(0.68)_intracellular_organelle GO:0043231_(0.67)_intracellular_membrane-bounded organelle GO:0005634_(0.59)_nucleus GO:0044446_(0.55)_intracellular_organelle_part GO:0044428_(0.53)_nuclear_part GO:0032991_(0.45)_macromolecular_complex GO:0009986_(0.30)_cell_surface GO:0044444_(0.26)_cytoplasmic_part GO:0016020_(0.24)_membrane GO:0071013_(0.23)_catalytic_step_2_spliceosome GO:0043234_(0.23)_protein_complex GO:0005737_(0.23)_cytoplasm | UniProt annotation: GO:0031012_extracellular_matrix GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ | ||
59 | >NX_O43934-1|MFS11_HUMAN UNC93-like protein MFSD11 GN=MFSD11 MSPESKKLFNIIILGVAFMFMFTAFQTCGNVAQTVIRSLNRTDFHGSGYT SMAIIYGVFSASNLITPSVVAIVGPQLSMFASGLFYSMYIAVFIQPFPWS FYTASVFIGIAAAVLWTAQGNCLTINSDEHSIGRNSGIFWALLQSSLFFG NLYIYFAWQGKTQISESDRRTVFIALTVISLVGTVLFFLIRKPDSENVLG EDESSDDQDMEVNESAQNNLTKAVDAFKKSFKLCVTKEMLLLSITTAYTG LELTFFSGVYGTCIGATNKFGAEEKSLIGLSGIFIGIGEILGGSLFGLLS KNNRFGRNPVVLLGILVHFIAFYLIFLNMPGDAPIAPVKGTDSSAYIKSS KEVAILCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAIFKFVQSICAA VAFFYSNYLLLHWQLLVMVIFGFFGTISFFTVEWEAAAFVARGSDYRSI chromosome location: 76735865-76781449 (17q25.1) Database cross references: | MF: GO:0005215_(0.85)_transporter_activity GO:0022857_(0.84)_transmembrane_transporter activity GO:0022892_(0.78)_substrate-specific_transporter activity GO:0022891_(0.77)_substrate-specific_transmembrane transporter_activity GO:0051119_(0.74)_sugar_transmembrane_transporter activity GO:0015145_(0.72)_monosaccharide_transmembrane transporter_activity GO:0015149_(0.71)_hexose_transmembrane_transporter activity GO:0005355_(0.70)_glucose_transmembrane transporter_activity GO:0008324_(0.67)_cation_transmembrane_transporter activity GO:0005351_(0.66)_sugar:proton_symporter_activity GO:0051183_(0.34)_vitamin_transporter_activity GO:0048029_(0.33)_monosaccharide_binding GO:0015146_(0.33)_pentose_transmembrane transporter_activity GO:0015148_(0.32)_D-xylose_transmembrane transporter_activity GO:0009679_(0.27)_hexose:proton_symporter_activity BP: GO:0006810_(0.82)_transport GO:0044699_(0.74)_single-organism_process GO:0071702_(0.70)_organic_substance_transport GO:0055085_(0.69)_transmembrane_transport GO:0008643_(0.68)_carbohydrate_transport GO:0015749_(0.67)_monosaccharide_transport GO:0008645_(0.66)_hexose_transport GO:0015758_(0.64)_glucose_transport GO:0034219_(0.61)_carbohydrate_transmembrane transport GO:0035428_(0.60)_hexose_transmembrane_transport GO:0046323_(0.47)_glucose_import GO:0065007_(0.38)_biological_regulation GO:0050896_(0.38)_response_to_stimulus GO:0006820_(0.38)_anion_transport GO:0051716_(0.35)_cellular_response_to_stimulus CC: GO:0016021_(1.00)_integral_component_of_membrane GO:0016020_(1.00)_membrane GO:0044464_(0.95)_cell_part GO:0005887_(0.77)_integral_component_of_plasma membrane GO:0005886_(0.70)_plasma_membrane GO:0044424_(0.20)_intracellular_part GO:0044444_(0.19)_cytoplasmic_part GO:0043226_(0.18)_organelle GO:0044422_(0.17)_organelle_part GO:0043227_(0.17)_membrane-bounded_organelle GO:0098590_(0.16)_plasma_membrane_region GO:0016324_(0.15)_apical_plasma_membrane GO:0043229_(0.13)_intracellular_organelle GO:0044446_(0.12)_intracellular_organelle_part GO:0043231_(0.12)_intracellular_membrane-bounded organelle | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ | ||
60 | >NX_Q6UX52-1|CQ099_HUMAN Uncharacterized protein C17orf99 GN=C17orf99 MGLPGLFCLAVLAASSFSKAREEEITPVVSIAYKVLEVFPKGRWVLITCC APQPPPPITYSLCGTKNIKVAKKVVKTHEPASFNLNVTLKSSPDLLTYFC WASSTSGAHVDSARLQMHWELWSKPVSELRANFTLQDRGAGPRVEMICQA SSGSPPITNSLIGKDGQVHLQQRPCHRQPANFSFLPSQTSDWFWCQAANN ANVQHSALTVVPPGGDQKMEDWQGPLESPILALPLYRSTRRLSEEEFGGF RIGNGEVRGRKAAAM chromosome location: 78146353-78166177 (17q25.3) Database cross references: | MF: GO:0004872_(0.63)_receptor_activity GO:0004888_(0.56)_transmembrane_signaling_receptor activity GO:0003824_(0.54)_catalytic_activity GO:0004672_(0.53)_protein_kinase_activity GO:0019199_(0.50)_transmembrane_receptor_protein kinase_activity GO:0097367_(0.49)_carbohydrate_derivative_binding GO:0035639_(0.47)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.47)_adenyl_ribonucleotide_binding GO:0032550_(0.47)_purine_ribonucleoside_binding GO:0046983_(0.39)_protein_dimerization_activity GO:0072341_(0.25)_modified_amino_acid_binding GO:0005543_(0.25)_phospholipid_binding GO:0042802_(0.24)_identical_protein_binding GO:0005102_(0.21)_receptor_binding GO:0042803_(0.18)_protein_homodimerization activity BP: GO:0044699_(0.79)_single-organism_process GO:0009987_(0.76)_cellular_process GO:0044763_(0.75)_single-organism_cellular_process GO:0032502_(0.68)_developmental_process GO:0044767_(0.67)_single-organism_developmental process GO:0048869_(0.61)_cellular_developmental_process GO:0016043_(0.61)_cellular_component_organization GO:0009653_(0.60)_anatomical_structure morphogenesis GO:0006928_(0.58)_movement_of_cell_or_subcellular component GO:0065007_(0.56)_biological_regulation GO:0050789_(0.55)_regulation_of_biological_process GO:0048856_(0.54)_anatomical_structure_development GO:0030030_(0.54)_cell_projection_organization GO:0050794_(0.53)_regulation_of_cellular_process GO:0032989_(0.53)_cellular_component_morphogenesis CC: GO:0031224_(1.00)_intrinsic_component_of_membrane GO:0016020_(1.00)_membrane GO:0044464_(0.98)_cell_part GO:0016021_(0.95)_integral_component_of_membrane GO:0005886_(0.90)_plasma_membrane GO:0044459_(0.75)_plasma_membrane_part GO:0005887_(0.63)_integral_component_of_plasma membrane GO:0043226_(0.50)_organelle GO:0043227_(0.49)_membrane-bounded_organelle GO:0031982_(0.42)_vesicle GO:0097458_(0.41)_neuron_part GO:0044424_(0.41)_intracellular_part GO:0042995_(0.40)_cell_projection GO:0031988_(0.38)_membrane-bounded_vesicle GO:0009986_(0.38)_cell_surface | UniProt annotation: GO:0002313_mature_B_cell_differentiation_involved in_immune_response GO:0005615_extracellular_space GO:2000558_positive_regulation_of_immunoglobulin production_in_mucosal_tissue GO:0005576_extracellular_region UniProt annotation score: ◉◉○○○ | ||
61 | >NX_O43760-1|SNG2_HUMAN Synaptogyrin-2 GN=SYNGR2 MESGAYGAAKAGGSFDLRRFLTQPQVVARAVCLVFALIVFSCIYGEGYSN AHESKQMYCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAYFPQISNATD RKYLVIGDLLFSALWTFLWFVGFCFLTNQWAVTNPKDVLVGADSVRAAIT FSFFSIFSWGVLASLAYQRYKAGVDDFIQNYVDPTPDPNTAYASYPGASV DNYQQPPFTQNAETTEGYQPPPVY chromosome location: 78168558-78173527 (17q25.3) Database cross references: | MF: GO:0043169_(0.37)_cation_binding GO:0047485_(0.23)_protein_N-terminus_binding GO:0042169_(0.23)_SH2_domain_binding GO:0016462_(0.22)_pyrophosphatase_activity GO:0015405_(0.22)_P-P-bond-hydrolysis-driven transmembrane_transporter_activity BP: GO:0006810_(0.66)_transport GO:0051649_(0.64)_establishment_of_localization_in cell GO:0051641_(0.64)_cellular_localization GO:0006605_(0.52)_protein_targeting GO:0065007_(0.51)_biological_regulation GO:0050789_(0.51)_regulation_of_biological_process GO:0051049_(0.31)_regulation_of_transport GO:0032411_(0.26)_positive_regulation_of transporter_activity GO:0050794_(0.25)_regulation_of_cellular_process GO:0044699_(0.25)_single-organism_process GO:0048168_(0.20)_regulation_of_neuronal_synaptic plasticity GO:0048172_(0.19)_regulation_of_short-term neuronal_synaptic_plasticity GO:0048169_(0.19)_regulation_of_long-term_neuronal synaptic_plasticity GO:0044765_(0.16)_single-organism_transport GO:0048489_(0.12)_synaptic_vesicle_transport CC: GO:0031594_(1.00)_neuromuscular_junction GO:0030672_(1.00)_synaptic_vesicle_membrane GO:0031988_(0.13)_membrane-bounded_vesicle GO:0008021_(0.10)_synaptic_vesicle GO:0070062_(0.06)_extracellular_exosome GO:0016021_(0.06)_integral_component_of_membrane GO:0043195_(0.01)_terminal_bouton | UniProt annotation: May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane. {ECO:0000250|UniProtKB:O54980}. (Microbial infection) May play a role in the assembly of cytoplasmic inclusion bodies required for SFTS phlebovirus replication. {ECO:0000269|PubMed:27226560}. GO:0030672_synaptic_vesicle_membrane GO:0005515_protein_binding GO:0070062_extracellular_exosome GO:0016021_integral_component_of_membrane GO:0048499_synaptic_vesicle_membrane_organization GO:0045055_regulated_exocytosis GO:0031594_neuromuscular_junction GO:0030054_cell_junction GO:0005811_lipid_droplet GO:0031410_cytoplasmic_vesicle GO:0045202_synapse GO:0016020_membrane GO:0008021_synaptic_vesicle GO:0030659_cytoplasmic_vesicle_membrane UniProt annotation score: ◉◉◉◉◉ NextProt annotation: (Microbial infection) May play a role in the assembly of cytoplasmic inclusion bodies required for SFTS phlebovirus replication. GO:0045055_regulated_exocytosis GO:0048499_synaptic_vesicle_membrane_organization GO:0005515_protein_binding | High: center_cells;_squamous_epithelial_cells) germinal_center_cells) pulp) | |
62 | >NX_Q96MC4-1|C295L_HUMAN CEP295 N-terminal-like protein GN=CEP295NL MCSGWSSSVIWRHTQFAVERCGFCGSSGPGAPLEPSTLGSKHLPWEAVSA GFADRNRNMDGAMWLSLCPDNEDLLWRKKHKLLQARGKGDLALQRRADAK LWKNYQLQRLAEELRRGYQEAQHLHVGGLDRLQSARLLGWGGGRARENEP DSQGPIQRRSARPPRAKEKHRAALSEERSCREELGQQHPRHSRPRKTAAS PEKPQTTKATGRMNSHLAPPEKRKGRPEPSTKSGGGRCAIHPRRSKGADL ERSNPLVAAVGEIGLVEEKEKGTARAGRRQLGKGAVCFVPALTSRSQGQS LEGKLRDLGQLWPADSSCRREAVSPASQCTLREKNKWQKELELAFEELFN INRKLKKHLCLYLALKPRMDQRPGEGHAFSEMQECGAGTPRGKKMADPEM LPAGEPRSPAEEEAQQAASKTDLKTFMGKAQNQKYQGTVKPTFRNGSQTL SPEAGIFINKEDSLLYSTESGQETPKLGTLAEGSLQLHLQDQADRVGSTA SRQRQKAEMEQRRQKQLESLEQMEHPDMSLEIHYKAELEKERREQRRARL AHLKSSSTRAQERERGSELSTTSPSGTSLADDDRHSQMIRDQQQQILQQN RLHKQFLEEARKCLREFQNIC chromosome location: 78870910-78903217 (17q25.3) Database cross references: | MF: GO:0003824_(0.63)_catalytic_activity GO:0016740_(0.50)_transferase_activity GO:0036094_(0.45)_small_molecule_binding GO:1901981_(0.44)_phosphatidylinositol_phosphate binding GO:0030234_(0.44)_enzyme_regulator_activity GO:0033218_(0.43)_amide_binding GO:0030246_(0.43)_carbohydrate_binding GO:0010485_(0.43)_H4_histone_acetyltransferase activity GO:0008375_(0.43)_acetylglucosaminyltransferase activity GO:0016787_(0.21)_hydrolase_activity GO:0017111_(0.20)_nucleoside-triphosphatase activity GO:0016887_(0.19)_ATPase_activity GO:0003774_(0.16)_motor_activity GO:0005198_(0.12)_structural_molecule_activity GO:0003777_(0.12)_microtubule_motor_activity BP: GO:0065007_(0.75)_biological_regulation GO:0050789_(0.72)_regulation_of_biological_process GO:0009987_(0.72)_cellular_process GO:0050794_(0.71)_regulation_of_cellular_process GO:0044699_(0.67)_single-organism_process GO:0044763_(0.65)_single-organism_cellular_process GO:0051128_(0.64)_regulation_of_cellular_component organization GO:0048518_(0.63)_positive_regulation_of biological_process GO:0048522_(0.62)_positive_regulation_of_cellular process GO:0033043_(0.61)_regulation_of_organelle organization GO:0010638_(0.58)_positive_regulation_of_organelle organization GO:0016043_(0.55)_cellular_component_organization GO:0032502_(0.51)_developmental_process GO:0044767_(0.49)_single-organism_developmental process GO:0051179_(0.48)_localization CC: GO:0044464_(1.00)_cell_part GO:0044424_(0.97)_intracellular_part GO:0044444_(0.83)_cytoplasmic_part GO:0043226_(0.83)_organelle GO:0044422_(0.81)_organelle_part GO:0044446_(0.80)_intracellular_organelle_part GO:0043229_(0.74)_intracellular_organelle GO:0043234_(0.63)_protein_complex GO:0043227_(0.59)_membrane-bounded_organelle GO:0044430_(0.58)_cytoskeletal_part GO:0043231_(0.57)_intracellular_membrane-bounded organelle GO:0005737_(0.53)_cytoplasm GO:0016020_(0.44)_membrane GO:0005829_(0.43)_cytosol GO:0043232_(0.42)_intracellular_non-membrane- bounded_organelle | UniProt annotation: GO:0005929_cilium GO:0042995_cell_projection UniProt annotation score: ◉◉○○○ | ||
63 | >NX_Q96N21-1|AP4AT_HUMAN AP-4 complex accessory subunit Tepsin GN=TEPSIN MAAAPPLRDRLSFLHRLPILLKGTSDDDVPCPGYLFEEIAKISHESPGSS QCLLEYLLSRLHSSSGHGKLKVLKILLYLCSHGSSFFLLILKRNSAFIQE AAAFAGPPDPLHGNSLYQKVRAAAQDLGSTLFSDTVLPLAPSQPLGTPPA TGMGSQARPHSTLQGFGYSKEHGRTAVRHQPGQAGGGWDELDSGPSSQNS SQNSDLSRVSDSGSHSGSDSHSGASREPGDLAERVEVVALSDCQQELSLV RTVTRGPRAFLSREEAQHFIKACGLLNCEAVLQLLTCHLRGTSECTQLRA LCAIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEA SCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVS SRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIP GGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAP QTSSQRTAAKEPPGSEPSAFAFLNA chromosome location: 81228277-81239091 (17q25.3) Database cross references: | MF: GO:0003824_(0.47)_catalytic_activity GO:0043167_(0.43)_ion_binding GO:0043169_(0.42)_cation_binding GO:0016740_(0.15)_transferase_activity GO:0016787_(0.11)_hydrolase_activity GO:0005198_(0.11)_structural_molecule_activity GO:1901363_(0.10)_heterocyclic_compound_binding GO:0097159_(0.10)_organic_cyclic_compound_binding GO:0016772_(0.09)_transferase_activity, transferring_phosphorus-containing_groups GO:0044877_(0.08)_macromolecular_complex_binding GO:0003676_(0.08)_nucleic_acid_binding GO:0098772_(0.07)_molecular_function_regulator GO:0005215_(0.07)_transporter_activity GO:0004872_(0.07)_receptor_activity GO:0001104_(0.07)_RNA_polymerase_II_transcription cofactor_activity BP: GO:0009987_(0.61)_cellular_process GO:0044699_(0.53)_single-organism_process GO:0065007_(0.52)_biological_regulation GO:0050789_(0.44)_regulation_of_biological_process GO:0050794_(0.42)_regulation_of_cellular_process GO:0044763_(0.41)_single-organism_cellular_process GO:0044767_(0.27)_single-organism_developmental process GO:0071704_(0.25)_organic_substance_metabolic process GO:0016043_(0.25)_cellular_component_organization GO:0044238_(0.24)_primary_metabolic_process GO:0044237_(0.24)_cellular_metabolic_process GO:0051179_(0.23)_localization GO:0044260_(0.22)_cellular_macromolecule_metabolic process GO:0007165_(0.22)_signal_transduction GO:0006810_(0.22)_transport CC: GO:0044424_(1.00)_intracellular_part GO:0032991_(0.64)_macromolecular_complex GO:0043234_(0.63)_protein_complex GO:0043226_(0.63)_organelle GO:0043229_(0.61)_intracellular_organelle GO:0005737_(0.60)_cytoplasm GO:0044422_(0.49)_organelle_part GO:0044446_(0.48)_intracellular_organelle_part GO:0043227_(0.45)_membrane-bounded_organelle GO:0044444_(0.44)_cytoplasmic_part GO:0043231_(0.42)_intracellular_membrane-bounded organelle GO:0016020_(0.41)_membrane GO:0044428_(0.38)_nuclear_part GO:0043232_(0.33)_intracellular_non-membrane- bounded_organelle GO:1902494_(0.32)_catalytic_complex | UniProt annotation: Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network. {ECO:0000305|PubMed:22472443, ECO:0000305|PubMed:26542808}. GO:0030124_AP-4_adaptor_complex GO:0005794_Golgi_apparatus GO:0030662_coated_vesicle_membrane GO:0032588_trans-Golgi_network_membrane GO:0031312_extrinsic_component_of_organelle membrane GO:0005515_protein_binding GO:0005737_cytoplasm GO:0031965_nuclear_membrane GO:0016607_nuclear_speck GO:0031410_cytoplasmic_vesicle GO:0016020_membrane GO:0005829_cytosol UniProt annotation score: ◉◉◉◉◉ NextProt annotation: Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network. GO:0005515_protein_binding | ||
64 | >NX_Q5BKU9-1|OXLD1_HUMAN Oxidoreductase-like domain-containing protein 1 GN=OXLD1 MLLRRVVEGGRAVAAAVRGSGARRFSSPDCCQRLPGGGSFLQRHHPGAQA PDGRRKFGTDHVEVGSQAGADGTRPPKASLPPELQPPTNCCMSGCPNCVW VEYADRLLQHFQDGGERALAALEEHVADENLKAFLRMEIRLHTRCGG chromosome location: 81665036-81666635 (17q25.3) Database cross references: | MF: GO:0003824_(0.94)_catalytic_activity GO:0016491_(0.87)_oxidoreductase_activity GO:0000166_(0.82)_nucleotide_binding GO:0071949_(0.73)_FAD_binding GO:0004128_(0.73)_cytochrome-b5_reductase activity,_acting_on_NAD(P)H GO:0016211_(0.52)_ammonia_ligase_activity GO:0035639_(0.33)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.33)_adenyl_ribonucleotide_binding GO:0032550_(0.33)_purine_ribonucleoside_binding GO:0030586_(0.14)_[methionine_synthase]_reductase activity BP: GO:0015701_(0.90)_bicarbonate_transport GO:0009084_(0.53)_glutamine_family_amino_acid biosynthetic_process GO:0008652_(0.53)_cellular_amino_acid_biosynthetic process GO:0006541_(0.53)_glutamine_metabolic_process GO:0071941_(0.34)_nitrogen_cycle_metabolic_process CC: GO:0043231_(1.00)_intracellular_membrane-bounded organelle GO:0044444_(0.94)_cytoplasmic_part GO:0005739_(0.90)_mitochondrion GO:0005737_(0.66)_cytoplasm GO:0016020_(0.19)_membrane GO:0005634_(0.18)_nucleus GO:0005886_(0.16)_plasma_membrane GO:0005829_(0.12)_cytosol GO:0044428_(0.11)_nuclear_part GO:0043234_(0.08)_protein_complex GO:0005654_(0.08)_nucleoplasm GO:0070062_(0.04)_extracellular_exosome GO:0045202_(0.04)_synapse GO:0043197_(0.04)_dendritic_spine GO:0034399_(0.04)_nuclear_periphery | UniProt annotation score: ◉○○○○ | ||
65 | >NX_Q2TAC2-1|CCD57_HUMAN Coiled-coil domain-containing protein 57 GN=CCDC57 MLPLGSEPALNELLLRKEEEWRALQAHRTQLQEAALQDTRSQLEEAQGKL RCLQEDFVYNLQVLEERDLELERYDAAFAQAREWEEARRAEVSELKIEAA KLRQALAREARKVEELQQQQQLAFQEHRLELERVHSDKNGEIDHHREQYE NLKWTLERKLEELDGELALQRQELLLEFESKMRKREHEFRLQADNMSNTA LSRELKVKLLHKELEALKEAGAKAAESLQRAEATNAELERKLQSRAGELQ DLEAMSRARVKDLEDKLHSVQLTRKKEEETFKRKHEELDRLAREKDAVLV AVKGAHVEQLQELQTRVLELQAHCETLEAQLRRAEWRQADTAKEKDAAID QLREDASTVKSAWDAQIAQLSKEMVSRDLQIQTLQEEEVKLKAQVARSQQ DIERYKQQLSLAVERERSLERDQVQLGLDWQRRCDDIERDQIQKSEALIQ GLSMAKSQVAAKLQETEQALQEQEVVLKAVTLERDQAVQALRMHGLPRPG AQMLLRQHEEEISKDFPSSEIQRLREQNTSLRNAIAQMRKEMEALSHQIP PPIQTAAESTDANQPDPEAGGDAATPDYVLALEAEIRTLKHKFKTLEKHL EDVLDPLKMSSPHAESQPSVRTSTETTGGSAQAGQAGGSVQAGQAGGSVQ AGPVSSGLALRKLGDRVQLLNLLVTRLRQKVLREPLEPAALQRELPREVD QVHLEVLELRKQVAELGKHLRIAQHGGAEPSGRKQPPASDAVALGREQDA KSAEDEAPSRHLGKHQPRSAQVGSRLDALQGPKTQHSIHTVTCKSPRQKE DRSPKPPQAPQHPEEHGRQSHSSSSFASGTLQDMWRLLDLGSSPSGVTSQ GDSTPELPAPPAADRRPVKMQAGIATPGMKTAAQAKAKTTGASRSHPAKA KGCQRPPKIRNYNIMD chromosome location: 82101460-82212830 (17q25.3) Database cross references: | MF: GO:0097367_(0.44)_carbohydrate_derivative_binding GO:0035639_(0.41)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.41)_adenyl_ribonucleotide_binding GO:0032550_(0.41)_purine_ribonucleoside_binding GO:0052813_(0.31)_phosphatidylinositol bisphosphate_kinase_activity GO:0052742_(0.31)_phosphatidylinositol_kinase activity GO:0035004_(0.31)_phosphatidylinositol_3-kinase activity GO:0016307_(0.31)_phosphatidylinositol_phosphate kinase_activity GO:0004872_(0.08)_receptor_activity GO:0008201_(0.05)_heparin_binding BP: GO:0009987_(0.91)_cellular_process GO:0044699_(0.81)_single-organism_process GO:0044763_(0.77)_single-organism_cellular_process GO:0065007_(0.61)_biological_regulation GO:0050794_(0.59)_regulation_of_cellular_process GO:0016043_(0.56)_cellular_component_organization GO:0048518_(0.50)_positive_regulation_of biological_process GO:0060255_(0.48)_regulation_of_macromolecule metabolic_process GO:0010604_(0.46)_positive_regulation_of macromolecule_metabolic_process GO:0035556_(0.43)_intracellular_signal transduction GO:0010468_(0.43)_regulation_of_gene_expression GO:0048017_(0.41)_inositol_lipid-mediated signaling GO:0071704_(0.40)_organic_substance_metabolic process GO:0044238_(0.40)_primary_metabolic_process GO:0044237_(0.40)_cellular_metabolic_process CC: GO:0044424_(1.00)_intracellular_part GO:0016020_(1.00)_membrane GO:0043234_(0.90)_protein_complex GO:0044425_(0.86)_membrane_part GO:0005942_(0.85)_phosphatidylinositol_3-kinase complex GO:0043226_(0.77)_organelle GO:0044444_(0.76)_cytoplasmic_part GO:0043229_(0.75)_intracellular_organelle GO:0005737_(0.74)_cytoplasm GO:0044446_(0.72)_intracellular_organelle_part GO:0005886_(0.69)_plasma_membrane GO:0043227_(0.67)_membrane-bounded_organelle GO:0043231_(0.66)_intracellular_membrane-bounded organelle GO:0005829_(0.60)_cytosol GO:0044430_(0.47)_cytoskeletal_part | UniProt annotation: GO:0005515_protein_binding UniProt annotation score: ◉◉◉◉◉ NextProt annotation: GO:0005515_protein_binding | High: epithelial_cells) cells) center_cells) glandular_cells) Langerhans) peripheral_nerve) | |
66 | >NX_Q9BQA9-1|CQ062_HUMAN Uncharacterized protein C17orf62 GN=C17orf62 MYLQVETRTSSRLHLKRAPGIRSWSLLVGILSIGLAAAYYSGDSLGWKLF YVTGCLFVAVQNLEDWEEAIFDKSTGKVVLKTFSLYKKLLTLFRAGHDQV VVLLHDVRDVSVEEEKVRYFGKGYMVVLRLATGFSHPLTQSAVMGHRSDV EAIAKLITSFLELHCLESPTELSQSSDSEAGDPASQS chromosome location: 82442589-82450829 (17q25.3) Database cross references: | MF: GO:0035639_(0.57)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.57)_adenyl_ribonucleotide_binding GO:0032550_(0.57)_purine_ribonucleoside_binding GO:0051427_(0.37)_hormone_receptor_binding GO:0031701_(0.37)_angiotensin_receptor_binding GO:0005126_(0.37)_cytokine_receptor_binding GO:0004672_(0.37)_protein_kinase_activity BP: GO:0044351_(0.83)_macropinocytosis GO:0048870_(0.32)_cell_motility GO:0048869_(0.32)_cellular_developmental_process GO:0046777_(0.32)_protein_autophosphorylation GO:0018108_(0.32)_peptidyl-tyrosine phosphorylation GO:0008283_(0.32)_cell_proliferation GO:0007165_(0.32)_signal_transduction GO:0006955_(0.32)_immune_response GO:0006952_(0.32)_defense_response CC: GO:0044424_(1.00)_intracellular_part GO:0044446_(0.95)_intracellular_organelle_part GO:0043226_(0.95)_organelle GO:0043229_(0.89)_intracellular_organelle GO:0044444_(0.84)_cytoplasmic_part GO:0043232_(0.79)_intracellular_non-membrane- bounded_organelle GO:0044430_(0.74)_cytoskeletal_part GO:0043227_(0.74)_membrane-bounded_organelle GO:0005856_(0.74)_cytoskeleton GO:0005737_(0.74)_cytoplasm GO:0043231_(0.68)_intracellular_membrane-bounded organelle GO:0005874_(0.68)_microtubule GO:0005829_(0.68)_cytosol GO:0005871_(0.63)_kinesin_complex GO:0016020_(0.53)_membrane | UniProt annotation: GO:0005515_protein_binding GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ NextProt annotation: GO:0005515_protein_binding |