sequence (NextProt isoform, UniProt entry, common name, gene name) | COFACTOR (MF in red, BP in blue, CC in green) | UniProt GO (reviewed in black; IEA-only in grey) UniProt annotation score (1 to 5) NextProt GO (GOLD in black; SILVER in grey) | Tissue-specific protein expression (Human Protein Atlas) | Tissue-specific RNA expression (GTEx Portal) | |
1 | >NX_Q8TBR7-2|FA57A_HUMAN FAM57A GN=FAM57A MLLTLAGGALFFPGLFALCTWALRRSQPGWSRTDCVMISTRLVSSVHAVL ATGSGIVIIRSCDDVITGRHWLAREYVWFLIPYMIYDSYAMYLCEWCRTR DQNRAPSLTLRNFLSRNRLMITHHAVILFVLVPVAQRLRGDLGDFFVGCI FTAELSTPFVSLGRVLIQLKQQHTLLYKVNGILTLATFLSCRILLFPFMY WSYGRQQGLSLLQVPFSIPFYCNVANAFLVAPQIYWFCLLCRKAVRLFDT PQAKKDG chromosome location: 732412-742972 (17p13.3) Database cross references: | MF: GO:0016740_(1.00)_transferase_activity GO:0050291_(0.99)_sphingosine_N-acyltransferase activity BP: GO:0032502_(0.69)_developmental_process GO:0044767_(0.64)_single-organism_developmental process GO:0048856_(0.59)_anatomical_structure_development GO:1901564_(0.57)_organonitrogen_compound metabolic_process GO:0006629_(0.57)_lipid_metabolic_process GO:0048869_(0.55)_cellular_developmental_process GO:0016043_(0.54)_cellular_component_organization GO:0007420_(0.54)_brain_development GO:0021952_(0.53)_central_nervous_system projection_neuron_axonogenesis GO:0001654_(0.53)_eye_development GO:0006672_(0.46)_ceramide_metabolic_process GO:0046467_(0.42)_membrane_lipid_biosynthetic process GO:0046513_(0.41)_ceramide_biosynthetic_process GO:0048523_(0.31)_negative_regulation_of_cellular process CC: GO:0005887_(1.00)_integral_component_of_plasma membrane GO:0005886_(1.00)_plasma_membrane GO:0005783_(0.98)_endoplasmic_reticulum GO:0097458_(0.37)_neuron_part GO:0042995_(0.37)_cell_projection | UniProt annotation: GO:0005886_plasma_membrane GO:0005515_protein_binding GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ NextProt annotation: GO:0005515_protein_binding | ||
2 | >NX_A6NGC4-1|TLCD2_HUMAN TLC domain-containing protein 2 GN=TLCD2 MAPTGLLVAGASFLAFRGLHWGLRRLPTPESAARDRWQWWNLCVSLAHSL LSGTGALLGLSLYPQMAADPIHGHPRWALVLVAVSVGYFLADGADLLWNQ TLGKTWDLLCHHLVVVSCLSTAVLSGHYVGFSMVSLLLELNSACLHLRKL LLLSRQAPSLAFSVTSWASLATLALFRLVPLGWMSLWLFRQHHQVPLALV TLGGIGLVTVGIMSIILGIRILVNDVLQSRPHPPSPGHEKTRGTRTRRDN GPVTSNSSTLSLKD chromosome location: 1702790-1710438 (17p13.3) Database cross references: | MF: GO:0016740_(0.86)_transferase_activity GO:0050291_(0.76)_sphingosine_N-acyltransferase activity GO:0005216_(0.59)_ion_channel_activity GO:0009881_(0.55)_photoreceptor_activity BP: GO:0006643_(0.76)_membrane_lipid_metabolic_process GO:0006672_(0.73)_ceramide_metabolic_process GO:0044765_(0.61)_single-organism_transport GO:0006811_(0.60)_ion_transport GO:0034220_(0.58)_ion_transmembrane_transport GO:0019538_(0.58)_protein_metabolic_process GO:0044267_(0.56)_cellular_protein_metabolic process GO:0050896_(0.55)_response_to_stimulus GO:0006464_(0.54)_cellular_protein_modification process GO:0018298_(0.53)_protein-chromophore_linkage GO:0007602_(0.53)_phototransduction GO:0032502_(0.52)_developmental_process GO:0048856_(0.50)_anatomical_structure_development GO:0046467_(0.48)_membrane_lipid_biosynthetic process GO:0046513_(0.46)_ceramide_biosynthetic_process CC: GO:0016021_(1.00)_integral_component_of_membrane GO:0016020_(1.00)_membrane GO:0005783_(0.75)_endoplasmic_reticulum GO:0005886_(0.55)_plasma_membrane | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
3 | >NX_O43149-1|ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand domain-containing protein 1 GN=ZZEF1 MGNAPSHSSEDEAAAAGGEGWGPHQDWAAVSGTTPGPGVAAPALPPAAAL LEPARLREAAAALLPTPPCESLVSRHRGALFRWLEERLGRGEESVTLEQF RELLEARGAGCSSEQFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQG ELSHIIRQLQACSLVPGFTDIFSESKEGLDIHSSMILRFLHRNRLSSAVM PYPMLEHCNNMCTMRSSVLKESLDQLVQKEKESPGDLTRSPEMDKLKSVA KCYAYIETSSNSADIDKMTNGETSSYWQSDGSACSHWIRLKMKPDVVLRH LSIAVAATDQSYMPQQVTVAVGRNASDLQEVRDVHIPSNVTGYVTLLENA NVSQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYW SLLTSLVTASMETNPAFVQTVLHNTQKALRHMPPLSLSPGSTDFSTFLSP NVLEEVDSFLIRITSCCSTPEVELTLLAFALARGSVAKVMSSLCTITDHL DTQYDASSLILSMASVRQNLLLKYGKPLQLTLQACDVKGKEDKSGPENLL VEPWTRDGFLTETGKTRASTIFSTGTESAFQVTQIRIMVRRGGIGAQCGL VFAYNSSSDKFCAEEHFKRFEKYDKWKLQELRQFVKSRIGCSSDDLGEDD PIGWFELEEEWDEADVKLQQCRVAKYLMVKFLCTRQESAERLGVQGLTIS GYLRPARAEAEQSVTCAHCRKDTEESVCGATLLLRTLQFIQQLAHDLVQQ KESGLKYKSFLDFAGLDLQIFWNFYSKLKQNPREECVSAQTLLLQLLQSC FSVLQGDVLAASEEEKAPIQSPKGVEAAKELYTHLCDVVDKVDGDSVPME ILKQEVRNTLLNGAAIFFPNRQTRRNHLFTMMNVTEQEHKQSLQLTFRSL CTYFSDKDPGGLLLLPEKNDLAKMNISEVLAVMDTLVSVAARECELLMLS GAPGEVGSVLFSLFWSVQGSLLSWCYLQLKSTDSGAKDLAVDLIEKYVGQ FLASMRAILESLFSQYSGKTIVERLCNSVFSMAARQLVIFLLDFCTLDIP HCVLLREFSVLTELLKKLCSGPEGGLRKLDVETWQQEQPVVLHTWTKESA HNYENNCHEVSVFVSPGATYFEVEFDDRCETEKRYDYLEFTDARGRKTRY DTKVGTDKWPKKVTFKAGPRLQFLFHSDSSHNEWGYKFTVTACGLPDVAV SWGLDLQLLVSRLMGRLASQCMALKSVRQLGSNMVVPQAKMALVLSSPLW KPVFRHQVCPELELEASWPTHPHRNSKEVKNIPDDPCRHFLLDFAQSEPA QNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPD LYEKLQKYVNSGGKIALSEEFAQVYSLADGIRIWMLEMKQKSLMSLGNEA EEKHSSEATEVNPESLAKECIEKSLLLLKFLPTGISSKESCEKLETADET SHLQPLNKRQRTSSVVEEHFQASVSPTEAAPPATGDQSPGLGTQPKLPSS SGLPAADVSPATAEEPLSPSTPTRRPPFTRGRLRLLSFRSMEEARLVPTV KEKYPVLKDVMDFIKDQSLSHRSVVKVLSLRKAQAQSILEVLKITQHCAE SLGQPHCFHPPFILFLLELLTCQKDFTNYFGHLEGCGADLHKEIRDTYYQ LVLFLVKAVKGFSSLNDRSLLPALSCVQTALLHLLDMGWEPNDLAFFVDI QLPDLLMKMSQENISVHDSVISQWSEEDELADAKQNSEWMDECQDGMFEA WYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQC SDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMNCNVCD DFDLCYGCYAAKKYSYGHLPTHSITAHPMVTIRISDRQRLIQPYIHNYSW LLFAALALYSAHLASAEDVDGEKLDPQTRSSATTLRSQCMQLVGDCLMKA HQGKGLKALALLGVLPDGDSSLEDQALPVTVPTGASEEQLEKKAVQGAEL SEAGNGKRAVHEEIRPVDFKQRNKADKGVSLSKDPSCQTQISDSPADASP PTGLPDAEDSEVSSQKPIEEKAVTPSPEQVFAECSQKRILGLLAAMLPPL KSGPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLLPA EVDAAVIKVLSAKHNLFAAGDSSIVPDGWKTTHLLFSLGAVCLDSRVGLD WACSMAEILRSLNSAPLWRDVIATFTDHCIKQLPFQLKHTNIFTLLVLVG FPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKD YQLVQKGGGQECGDSRAQLSQYSQHFAFIASHLLQSSMDSHCPEAVEATW VLSLALKGLYKTLKAHGFEEIRATFLQTDLLKLLVKKCSKGTGFSKTWLL RDLEILSIMLYSSKKEINALAEHGDLELDERGDREEEVERPVSSPGDPEQ KKLDPLEGLDEPTRICFLMAHDALNAPLHILRAIYELQMKKTDYFFLEVQ KRFDGDELTTDERIRSLAQRWQPSKSLRLEEQSAKAVDTDMIILPCLSRP ARCDQATAESNPVTQKLISSTESELQQSYAKQRRSKSAALLHKELNCKSK RAVRDYLFRVNEATAVLYARHVLASLLAEWPSHVPVSEDILELSGPAHMT YILDMFMQLEEKHEWEKILQKVLQGCREDMLGTMALAACQFMEEPGMEVQ VRESKHPYNNNTNFEDKVHIPGAIYLSIKFDSQCNTEEGCDELAMSSSSD FQQDRHSFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLG RFQTGFEILKQMLSEERVVPHLPLAKIWEWLVGVACRQTGHQRLKAIHLL LRIVRCCGHSDLCDLALLKPLWQLFTHMEYGLFEDVTQPGILLPLHRALT ELFFVTENRAQELGVLQDYLLALTTDDHLLRCAAQALQNIAAISLAINYP NKATRLWNVEC chromosome location: 4004445-4143020 (17p13.2) Database cross references: | MF: GO:0016740_(0.53)_transferase_activity GO:0004842_(0.32)_ubiquitin-protein_transferase activity BP: GO:0019538_(0.61)_protein_metabolic_process GO:0006464_(0.50)_cellular_protein_modification process GO:0032446_(0.36)_protein_modification_by_small protein_conjugation GO:0016567_(0.35)_protein_ubiquitination CC: GO:0005634_(0.47)_nucleus GO:0005737_(0.46)_cytoplasm | UniProt annotation: GO:0008270_zinc_ion_binding GO:0005509_calcium_ion_binding GO:0046872_metal_ion_binding UniProt annotation score: ◉◉◉◉◉ NextProt annotation: GO:0005509_calcium_ion_binding GO:0008270_zinc_ion_binding | ||
4 | >NX_Q2TAL5-1|SMTL2_HUMAN Smoothelin-like protein 2 GN=SMTNL2 MEPAPDAQEARTVREALGRYEAALEGAVRALHEDMRGLQRGVERRVAEAM RLAGPLARTVADLQRDNQRLQAQLERLTRQVEALGLASGMSPVPGTPGTP SPPPAPGVPDRAPRLGSARFASHATFSLSGRGQSLDHDEASESEMRKTSN SCIMENGHQPGAGPGDGPPEIAQNFSAPDPPRPRPVSLSLRLPHQPVTAI TRVSDRFSGETSAAALSPMSAATLGGLNPSPSEVITPWTPSPSEKNSSFT WSVPSSGYGAVTASKHSNSPPLVTPPQSPVSPQPPAITQVHRQGERRREL VRSQTLPRTSEAQARKALFEKWEQETAAGKGKGEARARLKRSQSFGVASA SSIKQILLEWCRSKTLGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDY NSLSPTQRQKNFELAFTMAENLANCERLIEVEDMMVMGRKPDPMCVFTYV QSLYNHLRRFE chromosome location: 4583999-4608319 (17p13.2) Database cross references: | MF: GO:0008092_(0.77)_cytoskeletal_protein_binding GO:0003779_(0.42)_actin_binding GO:1901363_(0.40)_heterocyclic_compound_binding GO:0097159_(0.40)_organic_cyclic_compound_binding GO:0050660_(0.37)_flavin_adenine_dinucleotide binding BP: GO:0016043_(0.70)_cellular_component_organization GO:0032502_(0.69)_developmental_process GO:0044767_(0.63)_single-organism_developmental process GO:0048856_(0.59)_anatomical_structure_development GO:0006996_(0.47)_organelle_organization GO:0007010_(0.45)_cytoskeleton_organization GO:1902589_(0.42)_single-organism_organelle organization GO:0048869_(0.41)_cellular_developmental_process GO:0030029_(0.41)_actin_filament-based_process GO:0030036_(0.39)_actin_cytoskeleton_organization GO:0048519_(0.32)_negative_regulation_of biological_process GO:0031032_(0.31)_actomyosin_structure organization CC: GO:0005737_(0.66)_cytoplasm GO:0016020_(0.52)_membrane GO:0043232_(0.51)_intracellular_non-membrane- bounded_organelle GO:0044430_(0.50)_cytoskeletal_part GO:0005856_(0.43)_cytoskeleton GO:0005886_(0.42)_plasma_membrane GO:0042995_(0.38)_cell_projection GO:0043234_(0.37)_protein_complex GO:0044459_(0.36)_plasma_membrane_part GO:0030054_(0.36)_cell_junction GO:0030055_(0.32)_cell-substrate_junction GO:0005912_(0.31)_adherens_junction | UniProt annotation: UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
5 | >NX_O14894-1|T4S5_HUMAN Transmembrane 4 L6 family member 5 GN=TM4SF5 MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLM GGFIGGGLMVLCPGIAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVLG AIYCLSVSGAGLRNGPRCLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPR VVPWNVTLFSLLVAASCLEIVLCGIQLVNATIGVFCGDCRKKQDTPH chromosome location: 4771884-4783213 (17p13.2) Database cross references: | MF: GO:0015370_(0.50)_solute:sodium_symporter_activity GO:0005326_(0.50)_neurotransmitter_transporter activity BP: GO:0048856_(1.00)_anatomical_structure_development GO:0044767_(1.00)_single-organism_developmental process GO:2000227_(0.64)_negative_regulation_of pancreatic_A_cell_differentiation GO:2000077_(0.64)_negative_regulation_of_type_B pancreatic_cell_development GO:0090104_(0.64)_pancreatic_epsilon_cell differentiation GO:0031018_(0.64)_endocrine_pancreas_development GO:0042246_(0.36)_tissue_regeneration GO:0044765_(0.34)_single-organism_transport CC: GO:0016021_(1.00)_integral_component_of_membrane | UniProt annotation: GO:0005887_integral_component_of_plasma_membrane GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
6 | >NX_Q7Z5L0-1|VMO1_HUMAN Vitelline membrane outer layer protein 1 homolog GN=VMO1 MERGAGAKLLPLLLLLRATGFTCAQTDGRNGYTAVIEVTSGGPWGDWAWP EMCPDGFFASGFSLKVEPPQGIPGDDTALNGIRLHCARGNVLGNTHVVES QSGSWGEWSEPLWCRGGAYLVAFSLRVEAPTTLGDNTAANNVRFRCSDGE ELQGPGLSWGDFGDWSDHCPKGACGLQTKIQGPRGLGDDTALNDARLFCC RS chromosome location: 4785285-4786433 (17p13.2) Database cross references: | MF: GO:0016787_(0.53)_hydrolase_activity GO:0008061_(0.36)_chitin_binding GO:0004568_(0.36)_chitinase_activity BP: GO:0048856_(0.35)_anatomical_structure_development CC: GO:0070062_(1.00)_extracellular_exosome | UniProt annotation: GO:0070062_extracellular_exosome GO:0005576_extracellular_region UniProt annotation score: ◉◉◉○○ NextProt annotation: | ||
7 | >NX_A8MU93-1|CQ100_HUMAN Uncharacterized protein C17orf100 GN=C17orf100 MASARGAKQSSPRVGTTRYTETSTVRVETSSHRVETSSRRVETSQRRSEG PSLSPSGKRLPRILEASSRHVESSSQRTETTSRHVRASSLRVETSLHCAE SPTPRPSRPPARTKKRPDEMLLPKGHQGARALSQDRKASSCQPASQLPGG PIIFGFMETNHKSM chromosome location: 6651718-6693202 (17p13.1) Database cross references: | BP: GO:0030308_(0.84)_negative_regulation_of_cell growth CC: GO:0005737_(0.88)_cytoplasm GO:0005634_(0.81)_nucleus GO:0043234_(0.77)_protein_complex GO:0016459_(0.76)_myosin_complex GO:0031988_(0.60)_membrane-bounded_vesicle GO:0016020_(0.59)_membrane GO:0042995_(0.44)_cell_projection GO:0016023_(0.44)_cytoplasmic,_membrane-bounded vesicle | UniProt annotation: UniProt annotation score: ◉○○○○ NextProt annotation: | ||
8 | >NX_Q8N2U0-1|TM256_HUMAN Transmembrane protein 256 GN=TMEM256 MAGPAAAFRRLGALSGAAALGFASYGAHGAQFPDAYGKELFDKANKHHFL HSLALLGVPHCRKPLWAGLLLASGTTLFCTSFYYQALSGDPSIQTLAPAG GTLLLLGWLALAL chromosome location: 7402975-7404137 (17p13.1) Database cross references: | MF: GO:0022892_(0.57)_substrate-specific_transporter activity GO:0017128_(0.55)_phospholipid_scramblase_activity GO:0008865_(0.45)_fructokinase_activity GO:0004454_(0.45)_ketohexokinase_activity BP: GO:0046835_(0.57)_carbohydrate_phosphorylation GO:0006810_(0.46)_transport GO:0044351_(0.43)_macropinocytosis CC: GO:0070062_(0.51)_extracellular_exosome GO:0016020_(0.41)_membrane | UniProt annotation: GO:0070062_extracellular_exosome GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
9 | >NX_Q0P670-1|SPEM2_HUMAN Uncharacterized protein SPEM2 GN=SPEM2 MENQLWHNTVRCCNQYQESPHDAEDILLLLLGLIVLVNIGINVATMMWHG LQNALDKMIDWATQKNEIQASESPPSGPPDKAQDVHIHCILDPVQVKMSR PTQYSSFSCHHFSNHHSSSLLRCVRRRRRRHRRCRRRCCNHQQRPQNYRQ IPHSHSVFRNPHRSQKMSQLHRVPFFDQEDPDSYLEEEDNLPFPYPKYPR RGWGGFYQRAGLPSNVGLWGHQGGILASLPPPSLYLSPELRCMPKRVEAR SELRLQSYGRHGSQSRLWGNVEAEQWASSPPPPHRLPPNPSWVPVGHSPY PSVGWMLYDSWDQRRRGTEGFERPPASVSRNARPEAQGCREHHSPQSHQQ SLLGHAYGQSHRSPHPSTEPLGYSSQDPREVRRRAADWAEALPAWRPLTT SASLTVLDEASHQRTPAPSSVLVPHSSQPWPKVQAADPAPPPTMFVPLSR NPGGNANYQVYDSLELKRQVQKSRARSSSLPPASTSTLRPSLHRSQTEKL N chromosome location: 7425615-7427568 (17p13.1) Database cross references: | BP: GO:0044767_(0.36)_single-organism_developmental process CC: GO:0043234_(0.57)_protein_complex GO:0005737_(0.53)_cytoplasm GO:0044428_(0.31)_nuclear_part GO:0043232_(0.31)_intracellular_non-membrane- bounded_organelle GO:0016020_(0.31)_membrane | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
10 | >NX_Q96T59-1|CDRTF_HUMAN CMT1A duplicated region transcript 15 protein GN=CDRT15 MFSCCFPTSRGCCFRNGGSESLFRRCRRRLIPHPRRLSPVVIRRIQVPQD SLGQALAGQATPEIPLGLQLHTVLVQEIQELIEAQTLAPGPCAEVRALPA PAAEPEPAWEEAPPERALELEGAPAKDQTNEELPEITEVPESIKRRLGRR VPAATPAPRGNLLLQAWMRVHSWASRLFAPNVLPGTGP chromosome location: 14235673-14236862 (17p12) Database cross references: | MF: GO:0030234_(0.57)_enzyme_regulator_activity GO:0016887_(0.55)_ATPase_activity GO:0003777_(0.55)_microtubule_motor_activity GO:0043178_(0.49)_alcohol_binding GO:0032934_(0.49)_sterol_binding GO:0015248_(0.49)_sterol_transporter_activity GO:0008047_(0.49)_enzyme_activator_activity GO:0071814_(0.40)_protein-lipid_complex_binding GO:0070405_(0.40)_ammonium_ion_binding GO:0042277_(0.40)_peptide_binding BP: GO:0006810_(0.68)_transport GO:0016043_(0.57)_cellular_component_organization GO:0071702_(0.55)_organic_substance_transport GO:0006928_(0.55)_movement_of_cell_or_subcellular component GO:0007165_(0.54)_signal_transduction GO:0065008_(0.53)_regulation_of_biological_quality GO:0044707_(0.53)_single-multicellular_organism process GO:0051239_(0.52)_regulation_of_multicellular organismal_process GO:0055092_(0.49)_sterol_homeostasis GO:0045940_(0.49)_positive_regulation_of_steroid metabolic_process GO:0042157_(0.49)_lipoprotein_metabolic_process GO:0034645_(0.49)_cellular_macromolecule biosynthetic_process GO:0034377_(0.49)_plasma_lipoprotein_particle assembly GO:0016101_(0.49)_diterpenoid_metabolic_process GO:0015914_(0.49)_phospholipid_transport CC: GO:0016020_(0.79)_membrane GO:0043234_(0.54)_protein_complex GO:0016021_(0.54)_integral_component_of_membrane GO:0044430_(0.47)_cytoskeletal_part GO:0005886_(0.47)_plasma_membrane GO:0005871_(0.44)_kinesin_complex GO:0070062_(0.35)_extracellular_exosome GO:0005829_(0.33)_cytosol GO:0005634_(0.33)_nucleus | UniProt annotation: UniProt annotation score: ◉○○○○ NextProt annotation: | ||
11 | >NX_Q8NAA5-1|LR75A_HUMAN Leucine-rich repeat-containing protein 75A GN=LRRC75A MGTRQTKGSLAERASPGAAPGPRRERPDFWASLLLRAGDKAGRAGAGMPP YHRRVGMVQELLRMVRQGRREEAGTLLQHLRQDLGMESTSLDDVLYRYAS FRNLVDPITHDLIISLARYIHCPKPEGDALGAMEKLCRQLTYHLSPHSQW RRHRGLVKRKPQACLKAVLAGSPPDNTVDLSGIPLTSRDLERVTSYLQRC GEQVDSVELGFTGLTDDMVLQLLPALSTLPRLTTLALNGNRLTRAVLRDL TDILKDPSKFPNVTWIDLGNNVDIFSLPQPFLLSLRKRSPKQGHLPTILE LGEGPGSGEEVREGTVGQEDPGGGPVAPAEDHHEGKETVAAAQT chromosome location: 16441577-16492153 (17p11.2) Database cross references: | MF: GO:0030234_(0.37)_enzyme_regulator_activity GO:0004857_(0.36)_enzyme_inhibitor_activity BP: GO:0044767_(0.48)_single-organism_developmental process GO:0065009_(0.45)_regulation_of_molecular_function GO:0050790_(0.44)_regulation_of_catalytic_activity GO:0051239_(0.43)_regulation_of_multicellular organismal_process GO:0019222_(0.40)_regulation_of_metabolic_process GO:0048518_(0.39)_positive_regulation_of biological_process GO:0044092_(0.39)_negative_regulation_of_molecular function GO:0009057_(0.39)_macromolecule_catabolic_process GO:0060255_(0.38)_regulation_of_macromolecule metabolic_process GO:0050793_(0.38)_regulation_of_developmental process GO:0031323_(0.38)_regulation_of_cellular_metabolic process GO:2000026_(0.37)_regulation_of_multicellular organismal_development GO:0090304_(0.37)_nucleic_acid_metabolic_process GO:0044265_(0.37)_cellular_macromolecule_catabolic process GO:0080090_(0.36)_regulation_of_primary_metabolic process CC: GO:0005737_(0.69)_cytoplasm GO:0043234_(0.58)_protein_complex GO:0016020_(0.57)_membrane GO:0005886_(0.45)_plasma_membrane GO:0044421_(0.38)_extracellular_region_part GO:0005634_(0.37)_nucleus GO:0031988_(0.36)_membrane-bounded_vesicle GO:0070062_(0.35)_extracellular_exosome GO:0031224_(0.32)_intrinsic_component_of_membrane GO:0044428_(0.31)_nuclear_part | UniProt annotation: UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
12 | >NX_Q5M775-1|CYTSB_HUMAN Cytospin-B GN=SPECC1 MRSAAKPWNPAIRAGGHGPDRVRPLPAASSGMKSSKSSTSLAFESRLSRL KRASSEDTLNKPGSTAASGVVRLKKTATAGAISELTESRLRSGTGAFTTT KRTGIPAPREFSVTVSRERSVPRGPSNPRKSVSSPTSSNTPTPTKHLRTP STKPKQENEGGEKAALESQVRELLAEAKAKDSEINRLRSELKKYKEKRTL NAEGTDALGPNVDGTSVSPGDTEPMIRALEEKNKNFQKELSDLEEENRVL KEKLIYLEHSPNSEGAASHTGDSSCPTSITQESSFGSPTGNQMSSDIDEY KKNIHGNALRTSGSSSSDVTKASLSPDASDFEHITAETPSRPLSSTSNPF KSSKCSTAGSSPNSVSELSLASLTEKIQKMEENHHSTAEELQATLQELSD QQQMVQELTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQER VKNEEPTTQEGKIIELEQKCTGILEQGRFEREKLLNIQQQLTCSLRKVEE ENQGALEMIKRLKEENEKLNEFLELERHNNNMMAKTLEECRVTLEGLKME NGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVARAEKDLLELSCNE LRQELLKANGEIKHVSSLLAKVEKDYSYLKEICDHQAEQLSRTSLKLQEK ASESDAEIKDMKETIFELEDQVEQHRAVKLHNNQLISELESSVIKLEEQK SDLERQLKTLTKQMKEETEEWRRFQADLQTAVVVANDIKCEAQQELRTVK RKLLEEEEKNARLQKELGDVQGHGRVVTSRAAPPPVDEEPESSEVDAAGR WPGVCVSRTSPTPPESATTVKSLIKSFDLGRPGGAGQNISVHKTPRSPLS GIPVRTAPAAAVSPMQRHSTYSSVRPASRGVTQRLDLPDLPLSDILKGRT ETLKPDPHLRKSPSLESLSRPPSLGFGDTRLLSASTRAWKPQSKLSVERK DPLAALAREYGGSKRNALLKWCQKKTQGYANIDITNFSSSWSDGLAFCAL LHTYLPAHIPYQELNSQEKKRNLLLAFEAAESVGIKPSLELSEMLYTDRP DWQSVMQYVAQIYKYFET chromosome location: 20009344-20319026 (17p11.2) Database cross references: | MF: GO:0008092_(0.53)_cytoskeletal_protein_binding GO:0046983_(0.45)_protein_dimerization_activity GO:0042802_(0.45)_identical_protein_binding GO:0019899_(0.45)_enzyme_binding GO:0003779_(0.43)_actin_binding GO:0042805_(0.42)_actinin_binding GO:0005198_(0.41)_structural_molecule_activity GO:1901363_(0.40)_heterocyclic_compound_binding GO:0097367_(0.40)_carbohydrate_derivative_binding GO:0097159_(0.40)_organic_cyclic_compound_binding GO:0032403_(0.40)_protein_complex_binding GO:0051015_(0.38)_actin_filament_binding GO:0044389_(0.38)_ubiquitin-like_protein_ligase binding GO:0003676_(0.38)_nucleic_acid_binding GO:0001948_(0.38)_glycoprotein_binding BP: GO:0016043_(0.67)_cellular_component_organization GO:0032502_(0.62)_developmental_process GO:0044767_(0.60)_single-organism_developmental process GO:0006996_(0.55)_organelle_organization GO:0048856_(0.51)_anatomical_structure_development GO:1902589_(0.49)_single-organism_organelle organization GO:0007010_(0.48)_cytoskeleton_organization GO:0048869_(0.46)_cellular_developmental_process GO:0051179_(0.45)_localization GO:0006928_(0.43)_movement_of_cell_or_subcellular component GO:0030029_(0.42)_actin_filament-based_process GO:0009653_(0.42)_anatomical_structure morphogenesis GO:0030036_(0.41)_actin_cytoskeleton_organization GO:0051641_(0.39)_cellular_localization GO:0022607_(0.37)_cellular_component_assembly CC: GO:0044430_(0.66)_cytoskeletal_part GO:0016020_(0.59)_membrane GO:0043232_(0.54)_intracellular_non-membrane- bounded_organelle GO:0030054_(0.51)_cell_junction GO:0005856_(0.51)_cytoskeleton GO:0005886_(0.48)_plasma_membrane GO:0044459_(0.47)_plasma_membrane_part GO:0042995_(0.45)_cell_projection GO:0005912_(0.45)_adherens_junction GO:0005737_(0.42)_cytoplasm GO:0030055_(0.41)_cell-substrate_junction GO:0005924_(0.38)_cell-substrate_adherens_junction GO:0005911_(0.36)_cell-cell_junction GO:0044449_(0.35)_contractile_fiber_part GO:0044448_(0.34)_cell_cortex_part | UniProt annotation: GO:0016020_membrane GO:0005634_nucleus UniProt annotation score: ◉◉◉◉◉ NextProt annotation: | High: cells) center_cells) glandular_cells) glandular_cells) germinal_center_cells) | |
13 | >NX_Q8N6N6-1|NATD1_HUMAN NATD1 GN=NATD1 MAHSAAAVPLGALEQGCPIRVEHDRRRRQFTVRLNGCHDRAVLLYEYVGK RIVDLQHTEVPDAYRGRGIAKHLAKAALDFVVEEDLKAHLTCWYIQKYVK ENPLPQYLERLQP chromosome location: 21238870-21253410 (17p11.2) Database cross references: | MF: GO:0004402_(0.33)_histone_acetyltransferase activity BP: GO:0006473_(0.68)_protein_acetylation GO:0018393_(0.44)_internal_peptidyl-lysine acetylation GO:0001702_(0.37)_gastrulation_with_mouth_forming second GO:0016573_(0.35)_histone_acetylation GO:0006474_(0.35)_N-terminal_protein_amino_acid acetylation CC: GO:0043234_(0.64)_protein_complex GO:0031248_(0.55)_protein_acetyltransferase complex GO:0005737_(0.36)_cytoplasm GO:0044428_(0.33)_nuclear_part GO:0044427_(0.33)_chromosomal_part | UniProt annotation: GO:0005515_protein_binding UniProt annotation score: ◉◉○○○ NextProt annotation: GO:0005515_protein_binding | ||
14 | >NX_A8MSI8-1|LYRM9_HUMAN LYR motif-containing protein 9 GN=LYRM9 MAPLPGAELVRRPLQLYRYLLRCCQQLPTKGIQQHYKHAVRQSFRVHSDE DNPERIQQIIKRAIEDADWIMNKYKKQN chromosome location: 27878314-27894752 (17q11.2) Database cross references: | MF: GO:0008137_(0.52)_NADH_dehydrogenase_(ubiquinone) activity BP: GO:0022607_(0.41)_cellular_component_assembly GO:0043623_(0.36)_cellular_protein_complex assembly GO:0070271_(0.32)_protein_complex_biogenesis GO:0033108_(0.32)_mitochondrial_respiratory_chain complex_assembly CC: GO:0005737_(0.56)_cytoplasm GO:0005739_(0.53)_mitochondrion GO:0044421_(0.42)_extracellular_region_part GO:0070062_(0.40)_extracellular_exosome GO:0016020_(0.40)_membrane GO:0005576_(0.40)_extracellular_region | UniProt annotation: UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
15 | >NX_P0DI83-1|NARR_HUMAN Ras-related protein Rab-34, isoform NARR GN=RAB34 MVGQPQPRDDVGSPRPRVIVGTIRPRVIVGTIRPRVIVGSARARPPPDGT PRPQLAAEESPRPRVIFGTPRARVILGSPRPRVIVSSPWPAVVVASPRPR TPVGSPWPRVVVGTPRPRVIVGSPRARVADADPASAPSQGALQGRRQDEH SGTRAEGSRPGGAAPVPEEGGRFARAQRLPPPRHLRLPGAPDRHRGQI chromosome location: 28714281-28718429 (17q11.2) Database cross references: | BP: GO:0032502_(0.51)_developmental_process GO:0016043_(0.32)_cellular_component_organization GO:0080090_(0.31)_regulation_of_primary_metabolic process GO:0060255_(0.31)_regulation_of_macromolecule metabolic_process GO:0031323_(0.31)_regulation_of_cellular_metabolic process CC: GO:0016020_(0.46)_membrane GO:0043234_(0.43)_protein_complex GO:0031224_(0.36)_intrinsic_component_of_membrane GO:0016021_(0.31)_integral_component_of_membrane | UniProt annotation: GO:0005730_nucleolus GO:0005634_nucleus UniProt annotation score: ◉◉◉◉◉ NextProt annotation: | High: nerve/ganglion) | |
16 | >NX_Q8WU58-1|F222B_HUMAN FAM222B GN=FAM222B MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAK KVANNPLTIKIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAG LLAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYATVAPSTLAHPQAQ ALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQ PMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPPNVTVSTSTIP LSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISR SLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGIS RVPTGYPSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAG PGFVGKAPAYPQELCLAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYF QPLWNNILPTPNSDSSGSQDLAMPFHGGQPTGAPLDCAAAPGAHYRAGTG GGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRAPGNRAPDPTE SRSLHIQHPGYR chromosome location: 28755978-28855232 (17q11.2) Database cross references: | MF: GO:0003676_(0.52)_nucleic_acid_binding GO:0043169_(0.32)_cation_binding BP: GO:0019222_(0.33)_regulation_of_metabolic_process GO:0060255_(0.32)_regulation_of_macromolecule metabolic_process GO:0031323_(0.32)_regulation_of_cellular_metabolic process CC: GO:0005654_(1.00)_nucleoplasm | UniProt annotation: GO:0005654_nucleoplasm UniProt annotation score: ◉◉○○○ NextProt annotation: | High: cells) center_cells;_squamous_epithelial_cells) glandular_cells) | |
17 | >NX_A4FU69-1|EFCB5_HUMAN EF-hand calcium-binding domain-containing protein 5 GN=EFCAB5 MNESASQEELRPAQENRKEDKERKWNLTEVKELHETLQSVPDVPVKEDTN SVVEKAMDEIKSQELNLEGQRKISPGSIKDSKTEASGNIAIRKSAKVIFA LDETELKSKPEHTWKKNLFERMEARAQAMQQKIIDKENLKKELEKKAEKK LPRDNLAKEWFNTDSMTLNNTAYLLDKLLPTLVPGVENMLTQVEKKKVLT EADTPSKFDPINYLGEYLIRNNPNYIKDPGMSGYQRLMKEVTEDLKIYVP DTICNRVSKMKENVKQNRKQRESIDKIIVKVANTRKQALQEQFDEWILDP KGMIPKSVIQNVLQEFFQNPDFKLGSHCKQLDITDSTEPRLNKMEFTEYI SSHIKDLKSEMFEELLKHLCHSADEFREVIKADMRRQMFAELFLHCDHGK VGFLDRQRTLALLELFYDHSSQMLRSLLRNPRQWPFIEFEEINLTELWGD MDNQKHIYEGFDKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTST PSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHT ESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSR ESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQK SEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEK RSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQK IEGKSWSGEFFTCNWKMKYVTFEDEEQANLIYGNSRFTDLHSIIRNIQSC KEVKGRTAFNGVSFNLLQFVQLLETFVGEDAPLSVSETLTSFFKEGYVET EQEKMNALEQFSQNAFQVRQRLLLEAIFQKWDSDGSGFLDLKEVDELLYT YKEGMEKESMKKAKLHIQFPKPHPGHEVRLSSKQFQNYIELVVSELRGNE DQVLESVVEFLMNALERSHIESLRNSARRKWLHQIQCAAETSGVSLEPVY SETFKALMQDAEAHGNKKISAHISLLEENLLLPEKGNVLLRNVACTLDDA QFVLNRVLYRDMKGISFTVVDEGKPIHVPQVQYHGNIFFWNQSRNKHDYN GSFLALPLQDAYMRIFGVLAVDTLRDPHEINIFLPHEIRFYQGVANVFST AYHYVHSREHILHIVITGIGWLYDVTSSITSITTYFVEPSPAQDSDYVLR NMMVTGQLGLTEIHKNPPTIHRKSCIFRDFLFKCTDSSEVVLASACGETH IVVPLRERTGEALGVLDFNIGQNRMLLCQEYKDLQKMMKVVQVACYEILG EFSGEIKKKYILEIENVREVQRAGILFFRIMLLELQESIQLLNSMEFVSL LLYDHTLVTEPNSPQDSKSMELEANVKLVRDILKAVILFFHPELEFSSDF GSWDKCKFYVNKYLVNNICAFDPTAKHVEVNVQLIDEYIRDHSRTEVWKF GNVVIEHLYHWIHICSALMKITKQLNSGITPPLPSKTDNYMYAKMPGEGL QEK chromosome location: 29929200-30108452 (17q11.2) Database cross references: | BP: GO:0016043_(0.40)_cellular_component_organization GO:0032502_(0.32)_developmental_process GO:0044767_(0.31)_single-organism_developmental process | UniProt annotation: GO:0005509_calcium_ion_binding GO:0046872_metal_ion_binding UniProt annotation score: ◉◉◉○○ NextProt annotation: GO:0005509_calcium_ion_binding | ||
18 | >NX_P34910-1|EVI2B_HUMAN EVI2B GN=EVI2B MDPKYFILILFCGHLNNTFFSKTETITTEKQSQPTLFTSSMSQVLANSQN TTGNPLGQPTQFSDTFSGQSISPAKVTAGQPTPAVYTSSEKPEAHTSAGQ PLAYNTKQPTPIANTSSQQAVFTSARQLPSARTSTTQPPKSFVYTFTQQS SSVQIPSRKQITVHNPSTQPTSTVKNSPRSTPGFILDTTSNKQTPQKNNY NSIAAILIGVLLTSMLVAIIIIVLWKCLRKPVLNDQNWAGRSPFADGETP DICMDNIRENEISTKRTSIISLTPWKPSKSTLLADDLEIKLFESSENIED SNNPKTEKIKDQVNGTSEDSADGSTVGTAVSSSDDADLPPPPPLLDLEGQ ESNQSDKPTMTIVSPLPNDSTSLPPSLDCLNQDCGDHKSEIIQSFPPLDS LNLPLPPVDFMKNQEDSNLEIQCQEFSIPPNSDQDLNESLPPPPAELL chromosome location: 31303766-31314112 (17q11.2) Database cross references: | MF: GO:0005198_(0.37)_structural_molecule_activity BP: GO:0051179_(0.43)_localization GO:0051234_(0.42)_establishment_of_localization GO:0006810_(0.41)_transport GO:0051649_(0.39)_establishment_of_localization_in cell GO:0051641_(0.39)_cellular_localization GO:0046907_(0.37)_intracellular_transport GO:0071702_(0.34)_organic_substance_transport GO:0051169_(0.33)_nuclear_transport GO:0050658_(0.32)_RNA_transport GO:0045184_(0.32)_establishment_of_protein localization CC: GO:0005887_(1.00)_integral_component_of_plasma membrane | UniProt annotation: Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells. {ECO:0000269|PubMed:28186500}. GO:2000035_regulation_of_stem_cell_division GO:0030854_positive_regulation_of_granulocyte differentiation GO:0061515_myeloid_cell_development GO:0005887_integral_component_of_plasma_membrane GO:0043066_negative_regulation_of_apoptotic process GO:0071157_negative_regulation_of_cell_cycle arrest GO:0045660_positive_regulation_of_neutrophil differentiation GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉◉◉ NextProt annotation: GO:0030854_positive_regulation_of_granulocyte differentiation GO:0043066_negative_regulation_of_apoptotic process GO:0045660_positive_regulation_of_neutrophil differentiation GO:0061515_myeloid_cell_development GO:0071157_negative_regulation_of_cell_cycle arrest GO:2000035_regulation_of_stem_cell_division | High: cells) germinal_center_cells) pulp) center_cells) | |
19 | >NX_Q96QE4-1|LR37B_HUMAN Leucine-rich repeat-containing protein 37B GN=LRRC37B MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSS RSSHLPWESPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKE LDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLP RLKWVQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERW SLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPG PPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEV TMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPP SDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPG LAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQD SLVQSETAPEEQKASTSTNICELCTCGDETLSCVGLSPKQRLRQVPVPEP DTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFE GLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAW HGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILT MTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEE ASVGNPEGAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLEI QLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLM KLLSEQQEAKALNVEWDTDQQKTNYINENMEQNEQKEQKSSELMKEVPGD DYKNKLIFAISVTVILIILIIIFCLIEVNSHKRASEKYKDNPSISGA chromosome location: 32007872-32053504 (17q11.2) Database cross references: | MF: GO:0005215_(0.35)_transporter_activity GO:0022892_(0.34)_substrate-specific_transporter activity BP: GO:0007165_(0.45)_signal_transduction GO:0032502_(0.42)_developmental_process GO:0044767_(0.41)_single-organism_developmental process GO:0051179_(0.35)_localization GO:0016043_(0.35)_cellular_component_organization GO:0051641_(0.34)_cellular_localization GO:0006810_(0.34)_transport GO:0051649_(0.33)_establishment_of_localization_in cell GO:0008104_(0.33)_protein_localization GO:0048583_(0.32)_regulation_of_response_to stimulus GO:0006886_(0.32)_intracellular_protein_transport GO:0007166_(0.31)_cell_surface_receptor_signaling pathway CC: GO:0005737_(0.49)_cytoplasm | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ NextProt annotation: | Medium: | |
20 | >NX_Q9Y2Y6-1|TMM98_HUMAN Transmembrane protein 98 GN=TMEM98 METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLI GAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKI CHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPL DPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVL REAALASEPDKGLPGPEGFLQEQSAI chromosome location: 32927910-32945106 (17q11.2) Database cross references: | MF: GO:0046914_(0.50)_transition_metal_ion_binding GO:0046906_(0.50)_tetrapyrrole_binding GO:0016676_(0.50)_oxidoreductase_activity,_acting on_a_heme_group_of_donors,_oxygen_as_acceptor GO:0015078_(0.50)_hydrogen_ion_transmembrane transporter_activity GO:0015002_(0.50)_heme-copper_terminal_oxidase activity GO:0009055_(0.50)_electron_carrier_activity BP: GO:0098662_(0.50)_inorganic_cation_transmembrane transport GO:0046034_(0.50)_ATP_metabolic_process GO:0045333_(0.50)_cellular_respiration GO:0016310_(0.50)_phosphorylation GO:0015672_(0.50)_monovalent_inorganic_cation transport GO:0006818_(0.50)_hydrogen_transport CC: GO:0005634_(0.52)_nucleus GO:0005783_(0.48)_endoplasmic_reticulum | UniProt annotation: GO:0005783_endoplasmic_reticulum GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ NextProt annotation: | ||
21 | >NX_Q8TC99-1|FNDC8_HUMAN Fibronectin type III domain-containing protein 8 GN=FNDC8 MASEALHQVGDGEEAVLKKENFNMMNALDQLPKPFSNPKSMNRTVTTKGL PLASKGNLVNFLEDDTINLLKPLPVEDSDCSSDETSISAFSSTLLNPIKL AVTQPNSSFFAGMLEGELNKLSFSPMAKNAENEDLALGPCPCPSKSQMAT RGLLDLDNPELETETSSTHSESSVVVDLPDTPFIFEHTVNNSTAVISWTY ALGKQPVSFYQLLLQEVAKTQENELPEAKNRPWIFNKILGTTVKLMELKP NTCYCLSVRAANTAGVGKWCKPYKFATLATDFSSFPENYPIQITVRRKEP RQKIVSIGPEEMRRLEDLEYLFPC chromosome location: 35121579-35130732 (17q12) Database cross references: | MF: GO:0097367_(0.51)_carbohydrate_derivative_binding GO:1901363_(0.50)_heterocyclic_compound_binding GO:0097159_(0.50)_organic_cyclic_compound_binding GO:0035639_(0.49)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.49)_adenyl_ribonucleotide_binding GO:0032550_(0.49)_purine_ribonucleoside_binding GO:0016740_(0.37)_transferase_activity GO:0004872_(0.37)_receptor_activity GO:0016787_(0.35)_hydrolase_activity GO:0004888_(0.35)_transmembrane_signaling_receptor activity GO:0004672_(0.35)_protein_kinase_activity GO:0008186_(0.31)_RNA-dependent_ATPase_activity GO:0008026_(0.31)_ATP-dependent_helicase_activity GO:0003724_(0.31)_RNA_helicase_activity BP: GO:0032502_(0.67)_developmental_process GO:0044767_(0.63)_single-organism_developmental process GO:0048856_(0.54)_anatomical_structure_development GO:0048869_(0.52)_cellular_developmental_process GO:0006928_(0.40)_movement_of_cell_or_subcellular component GO:0016043_(0.39)_cellular_component_organization GO:0019538_(0.36)_protein_metabolic_process GO:0006464_(0.35)_cellular_protein_modification process GO:0009653_(0.34)_anatomical_structure morphogenesis GO:0006796_(0.34)_phosphate-containing_compound metabolic_process GO:0051239_(0.32)_regulation_of_multicellular organismal_process GO:0007411_(0.32)_axon_guidance CC: GO:0005634_(0.96)_nucleus | UniProt annotation: GO:0005634_nucleus UniProt annotation score: ◉◉○○○ NextProt annotation: | High: preleptotene_spermatocytes;_sertoli_cells; spermatogonia) | |
22 | >NX_Q8WW18-1|CQ050_HUMAN Uncharacterized protein C17orf50 GN=C17orf50 MDKHGVKTPLWKKETEELRAEDAEQEEGKEGSEDEDEDNQRPLEDSATEG EEPPRVAEEGEGRERRSVSYCPLRQESSTQQVALLRRADSGFWGWLGPLA LLGGLTAPTDRKRSLPEEPCVLEIRRRPPRRGGCACCELLFCKKCRSLHS HPAYVAHCVLDHPDLGKAGAAGNS chromosome location: 35760897-35765079 (17q12) Database cross references: | CC: GO:0005737_(1.00)_cytoplasm GO:0043657_(0.90)_host_cell GO:0070062_(0.77)_extracellular_exosome GO:0016020_(0.77)_membrane GO:0005829_(0.77)_cytosol GO:0005634_(0.77)_nucleus GO:0044428_(0.56)_nuclear_part GO:0072372_(0.37)_primary_cilium GO:0034399_(0.37)_nuclear_periphery GO:0031965_(0.37)_nuclear_membrane GO:0015630_(0.37)_microtubule_cytoskeleton GO:0005739_(0.37)_mitochondrion GO:0005694_(0.37)_chromosome GO:0000775_(0.37)_chromosome,_centromeric_region GO:0000159_(0.37)_protein_phosphatase_type_2A complex | UniProt annotation: UniProt annotation score: ◉○○○○ NextProt annotation: | ||
23 | >NX_A8MV24-1|CQ098_HUMAN Uncharacterized protein C17orf98 GN=C17orf98 MAYLSECRLRLEKGFILDGVAVSTAARAYGRSRPKLWSAIPPYNAQQDYH ARSYFQSHVVPPLLRKTDQDHGGTGRDGWIVDYIHIFGQGQRYLNRRNWA GTGHSLQQVTGHDHYNADLKPIDGFNGRFGYRRNTPALRQSTSVFGEVTH FPLF chromosome location: 38835088-38841455 (17q12) Database cross references: | MF: GO:0015926_(0.48)_glucosidase_activity BP: GO:0051275_(0.37)_beta-glucan_catabolic_process GO:0030243_(0.37)_cellulose_metabolic_process CC: GO:0005576_(0.75)_extracellular_region | UniProt annotation: UniProt annotation score: ◉○○○○ NextProt annotation: | ||
24 | >NX_Q9BQS6-1|HSPB9_HUMAN Heat shock protein beta-9 GN=HSPB9 MQRVGNTFSNESRVASRCPSVGLAERNRVATMPVRLLRDSPAAQEDNDHA RDGFQMKLDAHGFAPEELVVQVDGQWLMVTGQQQLDVRDPERVSYRMSQK VHRKMLPSNLSPTAMTCCLTPSGQLWVRGQCVALALPEAQTGPSPRLGSL GSKASNLTR chromosome location: 42121431-42123352 (17q21.2) Database cross references: | MF: GO:0042802_(0.76)_identical_protein_binding GO:0042803_(0.63)_protein_homodimerization activity GO:0051082_(0.52)_unfolded_protein_binding GO:0005212_(0.50)_structural_constituent_of_eye lens GO:0032182_(0.39)_ubiquitin-like_protein_binding GO:0030291_(0.39)_protein_serine/threonine_kinase inhibitor_activity GO:0019900_(0.39)_kinase_binding GO:0003723_(0.37)_RNA_binding GO:0043169_(0.35)_cation_binding BP: GO:0050896_(0.82)_response_to_stimulus GO:0006950_(0.80)_response_to_stress GO:0009628_(0.71)_response_to_abiotic_stimulus GO:0042221_(0.60)_response_to_chemical GO:0009408_(0.60)_response_to_heat GO:0016043_(0.56)_cellular_component_organization GO:0044767_(0.52)_single-organism_developmental process GO:0048523_(0.51)_negative_regulation_of_cellular process GO:0042981_(0.51)_regulation_of_apoptotic_process GO:0006457_(0.51)_protein_folding GO:0043066_(0.50)_negative_regulation_of_apoptotic process GO:0022607_(0.49)_cellular_component_assembly GO:1901700_(0.48)_response_to_oxygen-containing compound GO:0048856_(0.48)_anatomical_structure_development GO:0031323_(0.48)_regulation_of_cellular_metabolic process CC: GO:0005634_(0.97)_nucleus GO:0005737_(0.96)_cytoplasm | UniProt annotation: GO:0005737_cytoplasm GO:0005634_nucleus GO:0005515_protein_binding UniProt annotation score: ◉◉◉○○ NextProt annotation: GO:0005515_protein_binding | ||
25 | >NX_Q96A25-1|T106A_HUMAN Transmembrane protein 106A GN=TMEM106A MGKTFSQLGSWREDENKSILSSKPAIGSKAVNYSSTGSSKSFCSCVPCEG TADASFVTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAV LICLVTSSFIVFFLFPRSVIVQPAGLNSSTVAFDEADIYLNITNILNISN GNYYPIMVTQLTLEVLHLSLVVGQVSNNLLLHIGPLASEQMFYAVATKIR DENTYKICTWLEIKVHHVLLHIQGTLTCSYLSHSEQLVFQSYEYVDCRGN ASVPHQLTPHPP chromosome location: 43211835-43220041 (17q21.31) Database cross references: | MF: GO:0008236_(0.36)_serine-type_peptidase_activity GO:0004175_(0.36)_endopeptidase_activity BP: GO:0048813_(1.00)_dendrite_morphogenesis GO:0032418_(1.00)_lysosome_localization GO:0007041_(0.93)_lysosomal_transport GO:0007040_(0.93)_lysosome_organization CC: GO:0016020_(0.97)_membrane | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
26 | >NX_B2RV13-1|CF97D_HUMAN Uncharacterized protein C17orf105 GN=C17orf105 MNNSLDYLAYPVIVSNHRQSTTFRKKLDFGHYVSHKNRIQIAKPTVDTKP PVAHTNHILKLSKLQGEQKKINKIEYENKQLCQKIANAHRGPAKVDCWNE YFSKSLNRETRNRELVRITMENQGILKRLVDRKPHYDRRASEIDWQNSRR YIRNTTRYLLSQNE chromosome location: 43780435-43787612 (17q21.31) Database cross references: | MF: GO:0016740_(0.44)_transferase_activity GO:0004842_(0.41)_ubiquitin-protein_transferase activity GO:0004185_(0.36)_serine-type_carboxypeptidase activity GO:0004181_(0.36)_metallocarboxypeptidase_activity BP: GO:0019538_(0.94)_protein_metabolic_process GO:0006464_(0.51)_cellular_protein_modification process GO:0042787_(0.49)_protein_ubiquitination_involved in_ubiquitin-dependent_protein_catabolic_process GO:1901564_(0.47)_organonitrogen_compound metabolic_process GO:0043603_(0.47)_cellular_amide_metabolic_process GO:0016485_(0.44)_protein_processing GO:0006518_(0.44)_peptide_metabolic_process CC: GO:0005737_(0.88)_cytoplasm GO:0005634_(0.81)_nucleus GO:0005829_(0.76)_cytosol GO:0044428_(0.54)_nuclear_part GO:0016020_(0.51)_membrane GO:0005654_(0.51)_nucleoplasm GO:0044421_(0.48)_extracellular_region_part GO:0044454_(0.45)_nuclear_chromosome_part GO:0005615_(0.44)_extracellular_space GO:0000790_(0.41)_nuclear_chromatin | UniProt annotation: UniProt annotation score: ◉◉○○○ NextProt annotation: | High: | |
27 | >NX_Q3MHD2-1|LSM12_HUMAN Protein LSM12 homolog GN=LSM12 MAAPPGEYFSVGSQVSCRTCQEQRLQGEVVAFDYQSKMLALKCPSSSGKP NHADILLINLQYVSEVEIINDRTETPPPLASLNVSKLASKARTEKEEKLS QAYAISAGVSLEGQQLFQTIHKTIKDCKWQEKNIVVMEEVVITPPYQVEN CKGKEGSALSHVRKIVEKHFRDVESQKILQRSQAQQPQKEAALSS chromosome location: 44034635-44067619 (17q21.31) Database cross references: | MF: GO:0003723_(0.59)_RNA_binding BP: GO:0090304_(0.79)_nucleic_acid_metabolic_process GO:0016070_(0.73)_RNA_metabolic_process GO:0022618_(0.39)_ribonucleoprotein_complex assembly GO:0000387_(0.32)_spliceosomal_snRNP_assembly CC: GO:0005576_(0.55)_extracellular_region GO:0005829_(0.47)_cytosol GO:0005634_(0.33)_nucleus GO:0036464_(0.31)_cytoplasmic_ribonucleoprotein granule | UniProt annotation: UniProt annotation score: ◉◉◉○○ NextProt annotation: | High: peripheral_nerve/ganglion) center_cells;_squamous_epithelial_cells) germinal_center_cells) | |
28 | >NX_Q8N3J3-1|CQ053_HUMAN Uncharacterized protein C17orf53 GN=C17orf53 MACSLQKLFAVEEEFEDEDFLSAVEDAENRFTGSLPVNAGRLRPVSSRPQ ETVQAQSSRLLLLHPTAPSEALGLPDLDLCLPASSTPSADSRPSCIGAAP LRPVSTSSSWIGNQRRVTVTEVLRETARPQSSALHPLLTFESQQQQVGGF EGPEQDEFDKVLASMELEEPGMELECGVSSEAIPILPAQQREGSVLAKKA RVVDLSGSCQKGPVPAIHKAGIMSAQDESLDPVIQCRTPRPPLRPGAVGH LPVPTALTVPTQQLHWEVCPQRSPVQALQPLQAARGTIQSSPQNRFPCQP FQSPSSWLSGKAHLPRPRTPNSSCSTPSRTSSGLFPRIPLQPQAPVSSIG SPVGTPKGPQGALQTPIVTNHLVQLVTAASRTPQQPTHPSTRAKTRRFPG PAGILPHQQSGRSLEDIMVSAPQTPTHGALAKFQTEIVASSQASVEEDFG RGPWLTMKSTLGLDERDPSCFLCTYSIVMVLRKQAALKQLPRNKVPNMAV MIKSLTRSTMDASVVFKDPTGEMQGTVHRLLLETCQNELKPGSVLLLKQI GVFSPSLRNHYLNVTPNNLVHIYSPDSGDGSFLKPSQPFPKDSGSFQHDV AAKPEEGFRTAQNLEAEASPEEELPEADDLDGLLSELPEDFFCGTSS chromosome location: 44141906-44162476 (17q21.31) Database cross references: | MF: GO:0016787_(0.43)_hydrolase_activity GO:0004175_(0.37)_endopeptidase_activity GO:0004252_(0.36)_serine-type_endopeptidase activity BP: GO:0016043_(0.62)_cellular_component_organization GO:0048518_(0.60)_positive_regulation_of biological_process GO:0051179_(0.58)_localization GO:0048519_(0.58)_negative_regulation_of biological_process GO:0065008_(0.57)_regulation_of_biological_quality GO:0048523_(0.57)_negative_regulation_of_cellular process GO:0006810_(0.57)_transport GO:0051239_(0.54)_regulation_of_multicellular organismal_process GO:0048583_(0.54)_regulation_of_response_to stimulus GO:1902578_(0.53)_single-organism_localization GO:0048584_(0.52)_positive_regulation_of_response to_stimulus GO:0044765_(0.52)_single-organism_transport GO:0016192_(0.52)_vesicle-mediated_transport GO:0051240_(0.51)_positive_regulation_of multicellular_organismal_process GO:0042127_(0.51)_regulation_of_cell_proliferation CC: GO:0005576_(0.91)_extracellular_region GO:0044421_(0.70)_extracellular_region_part GO:0005615_(0.67)_extracellular_space GO:0031982_(0.55)_vesicle GO:0031988_(0.54)_membrane-bounded_vesicle GO:0070062_(0.53)_extracellular_exosome GO:0016020_(0.53)_membrane GO:0005886_(0.36)_plasma_membrane | UniProt annotation: UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
29 | >NX_Q71RG4-1|TMUB2_HUMAN Transmembrane and ubiquitin-like domain-containing protein 2 GN=TMUB2 MISRHLQNNLMSVDPASSQAMELSDVTLIEGVGNEVMVVAGVVVLILALV LAWLSTYVADSGSNQLLGAIVSAGDTSVLHLGHVDHLVAGQGNPEPTELP HPSEGNDEKAEEAGEGRGDSTGEAGAGGGVEPSLEHLLDIQGLPKRQAGA GSSSPEAPLRSEDSTCLPPSPGLITVRLKFLNDTEELAVARPEDTVGALK SKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHCHRSPPGSAVP GPSASLAPSATEPPSLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPA TVSLVGVTVFFSFLVFGMYGR chromosome location: 44186970-44191731 (17q21.31) Database cross references: | MF: GO:1990841_(0.41)_promoter-specific_chromatin binding GO:0051718_(0.41)_DNA (cytosine-5-)-methyltransferase_activity,_acting on_CpG_substrates GO:0045322_(0.41)_unmethylated_CpG_binding GO:0042826_(0.41)_histone_deacetylase_binding GO:0030331_(0.41)_estrogen_receptor_binding GO:0019904_(0.41)_protein_domain_specific_binding GO:0008327_(0.41)_methyl-CpG_binding GO:0008270_(0.41)_zinc_ion_binding GO:0003723_(0.41)_RNA_binding GO:0003690_(0.41)_double-stranded_DNA_binding BP: GO:0019538_(0.78)_protein_metabolic_process GO:0019941_(0.63)_modification-dependent_protein catabolic_process GO:0006511_(0.62)_ubiquitin-dependent_protein catabolic_process GO:0043412_(0.56)_macromolecule_modification GO:0071840_(0.54)_cellular_component_organization or_biogenesis GO:0016043_(0.53)_cellular_component_organization GO:0048519_(0.49)_negative_regulation_of biological_process GO:0080090_(0.48)_regulation_of_primary_metabolic process GO:0060255_(0.48)_regulation_of_macromolecule metabolic_process GO:0090304_(0.47)_nucleic_acid_metabolic_process GO:0051246_(0.47)_regulation_of_protein_metabolic process GO:0050896_(0.47)_response_to_stimulus GO:0048523_(0.47)_negative_regulation_of_cellular process GO:0043161_(0.47)_proteasome-mediated_ubiquitin- dependent_protein_catabolic_process GO:0031323_(0.47)_regulation_of_cellular_metabolic process CC: GO:0005634_(1.00)_nucleus GO:0044428_(0.89)_nuclear_part GO:0005737_(0.81)_cytoplasm GO:0005654_(0.79)_nucleoplasm GO:0043234_(0.64)_protein_complex GO:0044427_(0.44)_chromosomal_part GO:0043025_(0.44)_neuronal_cell_body GO:0005721_(0.43)_pericentric_heterochromatin GO:0005657_(0.43)_replication_fork | UniProt annotation: GO:0005515_protein_binding GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ NextProt annotation: GO:0005515_protein_binding | High: peripheral_nerve/ganglion) cells) | |
30 | >NX_A8MVW0-1|F1712_HUMAN FAM171A2 GN=FAM171A2 MPPASGPSVLARLLPLLGLLLGSASRAPGKSPPEPPSPQEILIKVQVYVS GELVPLARASVDVFGNRTLLAAGTTDSEGVATLPLSYRLGTWVLVTAARP GFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLGSPGARS QPLVQFQRRAARLPVSSTYSQLWASLTPASTQQEMRAFPAFLGTEASSSG NGSWLELMPLTAVSVHLLTGNGTEVPLSGPIHLSLPVPSETRALTVGTSI PAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTAGL VTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQ HRKLQLSGPSDGNKRDQATSMSQLHLICGGPLEPAPSGDPEAPPPGPLHS AFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESAGLKGARSAEGP GGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFLL SQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLG GEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGG GEGWGAGRAAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPH PRAWFVSLDGRSNSQVRHSYIDLQAGGGARSTDASLDSGVDVHEARPARR RPAREERERAPPAAPPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLT PLLDEVAAPEGRAATVPRGRGRSRGDSSRSSASELRRDSLTSPEDELGAE VGDEAGDKKSPWQRREERPLMVFNVK chromosome location: 44353215-44363875 (17q21.31) Database cross references: | MF: GO:1901363_(0.58)_heterocyclic_compound_binding GO:0097159_(0.58)_organic_cyclic_compound_binding GO:0003676_(0.56)_nucleic_acid_binding GO:0019899_(0.54)_enzyme_binding GO:0017016_(0.52)_Ras_GTPase_binding GO:0022892_(0.47)_substrate-specific_transporter activity BP: GO:0016043_(0.52)_cellular_component_organization GO:0051179_(0.49)_localization GO:0006810_(0.46)_transport GO:0060255_(0.42)_regulation_of_macromolecule metabolic_process GO:0006996_(0.42)_organelle_organization GO:0080090_(0.41)_regulation_of_primary_metabolic process GO:0031323_(0.41)_regulation_of_cellular_metabolic process GO:0048519_(0.40)_negative_regulation_of biological_process GO:0019538_(0.40)_protein_metabolic_process GO:0051171_(0.39)_regulation_of_nitrogen_compound metabolic_process GO:0050896_(0.39)_response_to_stimulus GO:0048523_(0.39)_negative_regulation_of_cellular process GO:0032879_(0.39)_regulation_of_localization GO:0016192_(0.39)_vesicle-mediated_transport GO:0010468_(0.39)_regulation_of_gene_expression CC: GO:0005737_(0.66)_cytoplasm GO:0043234_(0.64)_protein_complex GO:0031982_(0.53)_vesicle GO:0031988_(0.52)_membrane-bounded_vesicle GO:0044421_(0.51)_extracellular_region_part GO:0070062_(0.48)_extracellular_exosome GO:0005634_(0.48)_nucleus GO:0044428_(0.40)_nuclear_part GO:0016020_(0.40)_membrane GO:0005829_(0.35)_cytosol GO:0031090_(0.34)_organelle_membrane | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ NextProt annotation: | ||
31 | >NX_Q96MW1-1|CCD43_HUMAN Coiled-coil domain-containing protein 43 GN=CCDC43 MAAPSEVAAIAPGEGDGGGGGFGSWLDGRLEALGVDRAVYGAYILGILQE EEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEV QAIATLIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDD SGATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRE RDKLAKQERKEKEKKRTQRGERKR chromosome location: 44673069-44689779 (17q21.31) Database cross references: | BP: GO:0006810_(0.44)_transport GO:0046907_(0.41)_intracellular_transport GO:0006886_(0.38)_intracellular_protein_transport GO:0006606_(0.35)_protein_import_into_nucleus GO:0006607_(0.32)_NLS-bearing_protein_import_into nucleus CC: GO:0005829_(0.70)_cytosol GO:0044428_(0.66)_nuclear_part GO:0005737_(0.53)_cytoplasm GO:0005654_(0.51)_nucleoplasm GO:0016020_(0.50)_membrane GO:0043234_(0.43)_protein_complex GO:0043228_(0.37)_non-membrane-bounded_organelle GO:0031090_(0.37)_organelle_membrane GO:0005643_(0.35)_nuclear_pore GO:0044463_(0.33)_cell_projection_part GO:0043232_(0.32)_intracellular_non-membrane- bounded_organelle GO:0030054_(0.31)_cell_junction | UniProt annotation: GO:0005829_cytosol GO:0005515_protein_binding UniProt annotation score: ◉◉◉○○ NextProt annotation: GO:0005515_protein_binding | Medium: cells) center_cells;_squamous_epithelial_cells) germinal_center_cells) | |
32 | >NX_Q9P298-1|HIG1B_HUMAN HIG1 domain family member 1B GN=HIGD1B MSANRRWWVPPDDEDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLR SRGSTKMSIHLIHTRVAAQACAVGAIMLGAVYTMYSDYVKRMAQDAGEK chromosome location: 44846353-44850480 (17q21.31) Database cross references: | MF: GO:0016740_(0.79)_transferase_activity GO:0061630_(0.71)_ubiquitin_protein_ligase activity BP: GO:0043066_(0.32)_negative_regulation_of_apoptotic process GO:0043623_(0.31)_cellular_protein_complex assembly CC: GO:0043234_(0.88)_protein_complex GO:0005634_(0.71)_nucleus GO:0044429_(0.53)_mitochondrial_part GO:0005737_(0.46)_cytoplasm GO:0044428_(0.45)_nuclear_part GO:0044427_(0.45)_chromosomal_part GO:0005739_(0.42)_mitochondrion GO:0016020_(0.38)_membrane GO:0043232_(0.37)_intracellular_non-membrane- bounded_organelle GO:0016021_(0.36)_integral_component_of_membrane GO:0097249_(0.32)_mitochondrial_respiratory_chain supercomplex GO:0031305_(0.32)_integral_component_of mitochondrial_inner_membrane | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
33 | >NX_A6NFU0-1|F187A_HUMAN Ig-like V-type domain-containing protein FAM187A GN=FAM187A MHLALTTVLLWAWGLQAFEIVEKENIFQRTPCPAFLMFENAAYLADMSFE LPCHCKPEEVPAVVWFYQKHLGSSHTKVLTDFDGRVLTEAAQVRVGSDML TRFSIRMFSLLVFRAQSEDSGLYFCGTRKGDYFYAYDVDIQNSEGMVATF QDKGQEPFADEYYGHLHVFTTFWEWTPCDRCGVRGEQWRIGLCYLQSPDL SPRYLKAVPDVVSCGSRAVPRKLRTKARDHTPEVLVRSCLVPCEKTKTIR EGVLAIINYVSKVGSRPWVPQVPIQFHQQRLGHGLIISCPGARPEHAVAW DKDRQHLYRTQYLKGVNRSMRVFIDHGNQLHIRFTQLDDRGIYYCWRQGV LVAGFRLGVTSHGHYPASFSDPETRSAVELTLIGYLLITAVFVTIHFCRC CCYLFHCCPSFSP chromosome location: 44899712-44905390 (17q21.31) Database cross references: | MF: GO:0004872_(0.55)_receptor_activity GO:0042802_(0.50)_identical_protein_binding GO:0046983_(0.48)_protein_dimerization_activity GO:0004888_(0.46)_transmembrane_signaling_receptor activity GO:0097367_(0.42)_carbohydrate_derivative_binding BP: GO:0006928_(0.64)_movement_of_cell_or_subcellular component GO:0032502_(0.63)_developmental_process GO:0044767_(0.60)_single-organism_developmental process GO:0007411_(0.59)_axon_guidance GO:0048856_(0.55)_anatomical_structure_development GO:0048869_(0.53)_cellular_developmental_process GO:0016043_(0.53)_cellular_component_organization GO:0051239_(0.52)_regulation_of_multicellular organismal_process GO:0007155_(0.52)_cell_adhesion GO:0048518_(0.51)_positive_regulation_of biological_process GO:0050793_(0.50)_regulation_of_developmental process GO:0048583_(0.50)_regulation_of_response_to stimulus GO:0009653_(0.50)_anatomical_structure morphogenesis GO:2000026_(0.49)_regulation_of_multicellular organismal_development GO:0098609_(0.49)_cell-cell_adhesion CC: GO:0031224_(0.93)_intrinsic_component_of_membrane GO:0016020_(0.92)_membrane GO:0016021_(0.82)_integral_component_of_membrane GO:0005886_(0.71)_plasma_membrane GO:0044459_(0.66)_plasma_membrane_part GO:0097458_(0.59)_neuron_part GO:0044421_(0.55)_extracellular_region_part GO:0043005_(0.53)_neuron_projection GO:0030424_(0.52)_axon GO:0031226_(0.51)_intrinsic_component_of_plasma membrane GO:0005887_(0.50)_integral_component_of_plasma membrane GO:0030054_(0.43)_cell_junction GO:0043025_(0.40)_neuronal_cell_body GO:0005737_(0.32)_cytoplasm GO:0005576_(0.32)_extracellular_region | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ NextProt annotation: | High: | |
34 | >NX_A6NMS7-1|L37A1_HUMAN Leucine-rich repeat-containing protein 37A GN=LRRC37A MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLT SNPLGPPESWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQ ESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKL KKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELR VKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLL EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP MEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHH QTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVE PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAA EHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG FTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ VQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTL PPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPD LGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPA QDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQ RLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVIT ELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLV PLTTLKNILMMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNSAC LTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIVEPEEPSDSSGINL SGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNS LAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA AEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKP FSKGTPSTSSPAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVH ARKKYRFHKTRSHVTHRTTKVKKSPKVRKKSYLSRLMLANRLPFSAAKSL INSPSQGAFSSLGDLSPQENPFLEVSALSEHFIEKNNTKHTTARNAFEEN DFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNV GTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIEN YINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFC LIVICCHRRSLQEDEEGFSRGIFRFLPWRGCSSRRESQDGLSSFGQPLWF KDLYKPLSATRINNHAWKLHKKSSNEDKILNRDPGDSEAPTEEEESEALP chromosome location: 46292733-46337794 (17q21.31) Database cross references: | BP: GO:0032502_(0.44)_developmental_process GO:0007165_(0.44)_signal_transduction GO:0044767_(0.42)_single-organism_developmental process GO:0016043_(0.35)_cellular_component_organization GO:0048583_(0.32)_regulation_of_response_to stimulus CC: GO:0005737_(0.38)_cytoplasm | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ NextProt annotation: | High: early_spermatids) spermatocytes) | |
35 | >NX_A6NM11-1|L37A2_HUMAN Leucine-rich repeat-containing protein 37A2 GN=LRRC37A2 MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLT SNPLGPPDSWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQ ESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKL KKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELR VKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLL EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP MEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHH QTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVE PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAA EHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG FTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ VQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTL PPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPD LGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPA QDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQ RLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVIT ELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLV PLTTLKNILMMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNSAC LTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIVEPEEPSDSSGINL SGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNS LAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKP FSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVH ARKKYRFHKTRSHVTHRTPKVKKSPKVRKKSYLSRLMLANRLPFSAAKSL INSPSQGAFSSLGDLSPQENPFLEVSAPSEHFIENNNTKHTTARNAFEEN DFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQTETKWEYNNV GTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIEN YINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFC LIVICCHRRSLQEDEEGFSRGIFRFLPWRGCSSRRESQDGLSSFGQPLWF KDMYKPLSATRINNHAWKLHKKSSNEDKILNRDPGDSEAPTEEEESEALP chromosome location: 46511511-46555650 (17q21.31) Database cross references: | BP: GO:0007165_(0.45)_signal_transduction GO:0032502_(0.44)_developmental_process GO:0044767_(0.42)_single-organism_developmental process GO:0016043_(0.35)_cellular_component_organization GO:0048583_(0.32)_regulation_of_response_to stimulus CC: GO:0005737_(0.37)_cytoplasm | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ NextProt annotation: | High: early_spermatids) spermatocytes) | |
36 | >NX_Q9BU68-1|PR15L_HUMAN Proline-rich protein 15-like protein GN=PRR15L MTTEIGWWKLTFLRKKKSTPKVLYEIPDTYAQTEGDAEPPRPDAGGPNSD FNTRLEKIVDKSTKGKHVKVSNSGRFKEKKKVRATLAENPNLFDDHEEGR SSK chromosome location: 47951967-47957878 (17q21.32) Database cross references: | MF: GO:0044877_(0.31)_macromolecular_complex_binding GO:0005524_(0.31)_ATP_binding GO:0004672_(0.31)_protein_kinase_activity BP: GO:0018108_(0.42)_peptidyl-tyrosine phosphorylation GO:0008283_(0.42)_cell_proliferation GO:0006955_(0.42)_immune_response GO:0006952_(0.42)_defense_response GO:2001236_(0.31)_regulation_of_extrinsic apoptotic_signaling_pathway GO:2001234_(0.31)_negative_regulation_of_apoptotic signaling_pathway GO:0043068_(0.31)_positive_regulation_of programmed_cell_death GO:0022610_(0.31)_biological_adhesion CC: GO:0005737_(0.84)_cytoplasm GO:0016020_(0.74)_membrane GO:0044459_(0.58)_plasma_membrane_part GO:0005829_(0.58)_cytosol GO:0098590_(0.37)_plasma_membrane_region GO:0005886_(0.37)_plasma_membrane GO:0043234_(0.32)_protein_complex GO:0005634_(0.32)_nucleus | UniProt annotation: UniProt annotation score: ◉○○○○ NextProt annotation: | High: | |
37 | >NX_Q9C073-1|F117A_HUMAN FAM117A GN=FAM117A MAGAAAGGRGGGAWGPGRGGAGGLRRGCSPPAPAGSPRAGLQPLRATIPF QLQQPHQRRDGGGRAASVPCSVAPEKSVCRPQPLQVRRTFSLDTILSSYL LGQWPRDADGAFTCCTNDKATQTPLSWQELEGERASSCAHKRSASWGSTD HRKEISKLKQQLQRTKLSRSGKEKERGSPLLGDHAVRGALRASPPSFPSG SPVLRLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILDIPDGHRAPAPP QSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTP NDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVF EEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRN CPSNPGSPLPPASPRPPPRKDPEASKASPLPFEPWQRTPPSEEPVLFQSS LMV chromosome location: 49710332-49789180 (17q21.33) Database cross references: | MF: GO:0022891_(0.51)_substrate-specific_transmembrane transporter_activity GO:0005459_(0.40)_UDP-galactose_transmembrane transporter_activity BP: GO:0032501_(0.48)_multicellular_organismal_process GO:0044767_(0.46)_single-organism_developmental process GO:0048856_(0.44)_anatomical_structure_development GO:0048869_(0.42)_cellular_developmental_process GO:0003008_(0.40)_system_process GO:0051179_(0.37)_localization GO:0072015_(0.36)_glomerular_visceral_epithelial cell_development GO:0006810_(0.36)_transport GO:0003094_(0.36)_glomerular_filtration CC: GO:0005737_(0.57)_cytoplasm | UniProt annotation: UniProt annotation score: ◉◉○○○ NextProt annotation: | High: peripheral_nerve/ganglion) | |
38 | >NX_Q8IZD0-1|SAM14_HUMAN Sterile alpha motif domain-containing protein 14 GN=SAMD14 MASSKLREPVDEVFDLDLAVPETARLDSSLHKARAQLLAKGRRHRPSRSR LRDSASSAEDGEGSDGPGGKVTDGCGSPLHRLRSPLHSGPGSPAGGSFCL DPPGLRRSLDEDEPPPSPLTRYRPLHNAASHEGLAAASCSPPRSAPSSDS SPSFVRRHPRAEPHSEDDSRDASPPEPASPTIGLDKKTRRKFLDLGVTLR RASTGKSRKEKGSNRLSMGSRESVEGSGRSGGSPFLPFSWFTDSGKGSAS SGSTTSPTCSPKHEGFSPKKSASQESTLSDDSTPPSSSPKIPSGPWQEAK CSYPYHTLSQSSDEFLDEPLPPVHHWTSQQVGQWLQSLNLEQYAAEFAAR QVDGPQLLQLDGSKLKSLGLSNSHDRALVKRKLKEMAAAAEKERKAQEKA ARQREKLRRREQEAKKS chromosome location: 50110040-50129882 (17q21.33) Database cross references: | MF: GO:0044877_(0.48)_macromolecular_complex_binding GO:0032403_(0.47)_protein_complex_binding GO:0051015_(0.45)_actin_filament_binding GO:1901363_(0.43)_heterocyclic_compound_binding GO:0097159_(0.43)_organic_cyclic_compound_binding GO:0043169_(0.42)_cation_binding GO:0097367_(0.41)_carbohydrate_derivative_binding GO:0017076_(0.41)_purine_nucleotide_binding GO:0035639_(0.40)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.40)_adenyl_ribonucleotide_binding GO:0032550_(0.40)_purine_ribonucleoside_binding GO:0016879_(0.40)_ligase_activity,_forming_carbon- nitrogen_bonds BP: GO:0016043_(0.64)_cellular_component_organization GO:0007165_(0.61)_signal_transduction GO:0030030_(0.49)_cell_projection_organization GO:0035556_(0.47)_intracellular_signal transduction GO:0019932_(0.46)_second-messenger-mediated signaling GO:0031175_(0.45)_neuron_projection_development GO:0019722_(0.45)_calcium-mediated_signaling GO:0007015_(0.44)_actin_filament_organization CC: GO:0005737_(0.81)_cytoplasm GO:0043232_(0.61)_intracellular_non-membrane- bounded_organelle GO:0097458_(0.53)_neuron_part GO:0042995_(0.51)_cell_projection GO:0044456_(0.50)_synapse_part GO:0043005_(0.50)_neuron_projection GO:0016020_(0.50)_membrane GO:0005856_(0.50)_cytoskeleton GO:0015629_(0.42)_actin_cytoskeleton GO:0014069_(0.42)_postsynaptic_density GO:0030425_(0.38)_dendrite GO:0005829_(0.33)_cytosol | UniProt annotation: UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
39 | >NX_Q6AI12-1|ANR40_HUMAN Ankyrin repeat domain-containing protein 40 GN=ANKRD40 MNALLEQKEQQERLREAAALGDIREVQKLVESGVDVNSQNEVNGWTCLHW ACKRNHGQVVSYLLKSGADKEILTTKGEMPVQLTSRREIRKIMGVEEEDD DDDDDDNLPQLKKESELPFVPNYLANPAFPFIYTPTAEDSAQMQNGGPST PPASPPADGSPPLLPPGEPPLLGTFPRDHTSLALVQNGDVSAPSAILRTP ESTKPGPVCQPPVSQSRSLFSSVPSKPPMSLEPQNGTYAGPAPAFQPFFF TGAFPFNMQELVLKVRIQNPSLRENDFIEIELDRQELTYQELLRVCCCEL GVNPDQVEKIRKLPNTLLRKDKDVARLQDFQELELVLMISENNFLFRNAA STLTERPCYNRRASKLTY chromosome location: 50693190-50707924 (17q21.33) Database cross references: | MF: GO:0019899_(0.64)_enzyme_binding GO:0044389_(0.62)_ubiquitin-like_protein_ligase binding GO:0008092_(0.62)_cytoskeletal_protein_binding GO:0030507_(0.57)_spectrin_binding GO:0008093_(0.57)_cytoskeletal_adaptor_activity GO:0044877_(0.51)_macromolecular_complex_binding GO:0008134_(0.51)_transcription_factor_binding GO:0005048_(0.50)_signal_sequence_binding GO:0005200_(0.49)_structural_constituent_of cytoskeleton GO:0051117_(0.48)_ATPase_binding BP: GO:0060255_(0.62)_regulation_of_macromolecule metabolic_process GO:0007165_(0.62)_signal_transduction GO:0080090_(0.61)_regulation_of_primary_metabolic process GO:0031323_(0.61)_regulation_of_cellular_metabolic process GO:0051179_(0.60)_localization GO:0048522_(0.60)_positive_regulation_of_cellular process GO:0016043_(0.60)_cellular_component_organization GO:0065008_(0.58)_regulation_of_biological_quality GO:0050896_(0.58)_response_to_stimulus GO:0048519_(0.58)_negative_regulation_of biological_process GO:0006355_(0.58)_regulation_of_transcription, DNA-templated GO:0048523_(0.57)_negative_regulation_of_cellular process GO:0010604_(0.57)_positive_regulation_of macromolecule_metabolic_process GO:0006810_(0.57)_transport GO:0031325_(0.56)_positive_regulation_of_cellular metabolic_process CC: GO:0005737_(0.77)_cytoplasm GO:0005634_(0.65)_nucleus GO:0016020_(0.63)_membrane GO:0005886_(0.55)_plasma_membrane GO:0044459_(0.51)_plasma_membrane_part GO:0043234_(0.51)_protein_complex GO:0016021_(0.46)_integral_component_of_membrane GO:0005829_(0.43)_cytosol GO:0097458_(0.34)_neuron_part | UniProt annotation: GO:0005515_protein_binding UniProt annotation score: ◉◉◉○○ NextProt annotation: GO:0005515_protein_binding | High: peripheral_nerve/ganglion) center_cells;_squamous_epithelial_cells) glandular_cells) Langerhans) cells;_neuronal_cells) germinal_center_cells) | |
40 | >NX_Q0P5P2-1|CQ067_HUMAN Uncharacterized protein C17orf67 GN=C17orf67 MASFKLADSVWEDSLSKRQRNQGRMKTLPVLVLSLTLLTVFSETSPILTE KQAKQLLRSRRQDRPSKPGFPDEPMREYMHHLLALEHRAEEQFLEHWLNP HCKPHCDRNRIHPV chromosome location: 56791913-56838773 (17q22) Database cross references: | MF: GO:0043169_(0.58)_cation_binding GO:0004112_(0.58)_cyclic-nucleotide phosphodiesterase_activity GO:0032561_(0.48)_guanyl_ribonucleotide_binding GO:0030551_(0.48)_cyclic_nucleotide_binding BP: GO:0046068_(0.48)_cGMP_metabolic_process GO:0009214_(0.48)_cyclic_nucleotide_catabolic process GO:0009154_(0.48)_purine_ribonucleotide_catabolic process GO:2000243_(0.37)_positive_regulation_of reproductive_process GO:1900542_(0.37)_regulation_of_purine_nucleotide metabolic_process GO:0090075_(0.37)_relaxation_of_muscle GO:0071902_(0.37)_positive_regulation_of_protein serine/threonine_kinase_activity GO:0060281_(0.37)_regulation_of_oocyte_development GO:0055117_(0.37)_regulation_of_cardiac_muscle contraction GO:0050868_(0.37)_negative_regulation_of_T_cell activation GO:0050672_(0.37)_negative_regulation_of lymphocyte_proliferation GO:0045988_(0.37)_negative_regulation_of_striated muscle_contraction GO:0045822_(0.37)_negative_regulation_of_heart contraction GO:0043902_(0.37)_positive_regulation_of_multi- organism_process GO:0043410_(0.37)_positive_regulation_of_MAPK cascade CC: GO:0005829_(0.53)_cytosol GO:0005737_(0.47)_cytoplasm GO:0016020_(0.33)_membrane | UniProt annotation: GO:0005515_protein_binding GO:0005576_extracellular_region UniProt annotation score: ◉◉○○○ NextProt annotation: GO:0005515_protein_binding | ||
41 | >NX_Q9NWM3-1|CUED1_HUMAN CUE domain-containing protein 1 GN=CUEDC1 MTSLFRRSSSGSGGGGTAGARGGGGGTAAPQELNNSRPARQVRRLEFNQA MDDFKTMFPNMDYDIIECVLRANSGAVDATIDQLLQMNLEGGGSSGGVYE DSSDSEDSIPPEILERTLEPDSSDEEPPPVYSPPAYHMHVFDRPYPLAPP TPPPRIDALGSGAPTSQRRYRNWNPPLLGNLPDDFLRILPQQLDSIQGNA GGPKPGSGEGCPPAMAGPGPGDQESRWKQYLEDERIALFLQNEEFMKELQ RNRDFLLALERDRLKYESQKSKSSSVAVGNDFGFSSPVPGTGDANPAVSE DALFRDKLKHMGKSTRRKLFELARAFSEKTKMRKSKRKHLLKHQSLGAAA STANLLDDVEGHACDEDFRGRRQEAPKVEEGLREGQ chromosome location: 57861243-57955323 (17q22) Database cross references: | MF: GO:0022892_(0.35)_substrate-specific_transporter activity GO:0019899_(0.32)_enzyme_binding BP: GO:0006796_(0.55)_phosphate-containing_compound metabolic_process GO:0016310_(0.52)_phosphorylation CC: GO:0005634_(0.85)_nucleus GO:0005737_(0.75)_cytoplasm GO:0044428_(0.66)_nuclear_part GO:0016020_(0.60)_membrane GO:0043234_(0.58)_protein_complex GO:0070062_(0.56)_extracellular_exosome GO:0005643_(0.54)_nuclear_pore GO:0005829_(0.36)_cytosol | UniProt annotation: UniProt annotation score: ◉◉○○○ NextProt annotation: | High: peripheral_nerve/ganglion) cells) epithelial_cells) | |
42 | >NX_Q8NEP4-1|CQ047_HUMAN Uncharacterized protein C17orf47 GN=C17orf47 MVKTNKPGAKVAVSAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSH RRSEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPRGPETGPRTESSRHS SPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHASSI PDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGVRVPRRILSYPKDE AVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESET GPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYS AYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHV TVPSVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKP SIHAELELTPRPLPPRSLPRYGPDSSWWPLLNPEVETPQSQLTTPDFEPK CSPSLDLLLSGFKIDSSPFCEDLKFQREKASLSPPSPPKEFPSWAPLSEV PQTPKHTCKQPIQRFTAFFLDVSEEMYNRVIWWLKGLCFSLLWAHCGSLG DGRTGEEWHLCIYRAGSFRR chromosome location: 58541587-58544368 (17q22) Database cross references: | MF: GO:1901363_(0.37)_heterocyclic_compound_binding GO:0097159_(0.37)_organic_cyclic_compound_binding GO:0003676_(0.35)_nucleic_acid_binding CC: GO:0043234_(0.68)_protein_complex GO:0005737_(0.41)_cytoplasm GO:1990234_(0.34)_transferase_complex GO:0043232_(0.33)_intracellular_non-membrane- bounded_organelle GO:0016020_(0.33)_membrane | UniProt annotation: UniProt annotation score: ◉○○○○ NextProt annotation: | ||
43 | >NX_Q86X59-1|CQ082_HUMAN Putative uncharacterized protein C17orf82 GN=C17orf82 MGRPLEGQPLRALDLYPEPAFLRSGKDPKSSPASSPSFAVLGPEVRSTGG QAGSRRRPSAPCSQDRAAAEGAPALLGGSPSSGSPGHPPGSAFGVEAGCR ALNVSEHARGGFALGLPFGLSGGAYLFLLLDGAGDPKPTPEAPISSADGR AWFPSESSWQLPQLPAGSTSGSEPRARPGLGPRQLLTGPRDGAAGQGPGR GLTARLGREREIDCGPRQAGHGGTATDTGRAGSGARHRPPRDRGTPGLRT H chromosome location: 61411751-61413280 (17q23.2) Database cross references: | MF: GO:0015926_(0.39)_glucosidase_activity GO:0003676_(0.34)_nucleic_acid_binding BP: GO:0016043_(0.55)_cellular_component_organization GO:0032502_(0.52)_developmental_process GO:0048856_(0.48)_anatomical_structure_development GO:0051179_(0.45)_localization GO:0006810_(0.44)_transport GO:0043933_(0.42)_macromolecular_complex_subunit organization GO:0022607_(0.42)_cellular_component_assembly GO:0065003_(0.39)_macromolecular_complex_assembly GO:0051641_(0.39)_cellular_localization GO:0051649_(0.38)_establishment_of_localization_in cell GO:0048731_(0.38)_system_development GO:0006139_(0.38)_nucleobase-containing_compound metabolic_process GO:0090304_(0.37)_nucleic_acid_metabolic_process GO:0034622_(0.37)_cellular_macromolecular_complex assembly GO:0046907_(0.36)_intracellular_transport CC: GO:0005576_(0.53)_extracellular_region GO:0016020_(0.48)_membrane GO:0005737_(0.44)_cytoplasm GO:0043234_(0.39)_protein_complex GO:0005886_(0.33)_plasma_membrane | UniProt annotation: GO:0005515_protein_binding UniProt annotation score: ◉○○○○ NextProt annotation: GO:0005515_protein_binding | ||
44 | >NX_Q8N7B9-1|EFCB3_HUMAN EF-hand calcium-binding domain-containing protein 3 GN=EFCAB3 MAVSEIKPKLKLNPLTKVPISHNKRDRDLPGSLQCQLQHKEKKLSASQMA AFQDAYNFFYKDKTGCIDFHGLMCTVAKLGMNLTKHDVYNELKCADIDRD GKVNFSDFIKVLTDKNLFLKAVVPEKETCLDLAGNPGILLFEILSRLLET SALPRKSIIEIVSYFQRKFQHTGPGMLWSPYTMGYGKRTLKPDICTPPSS SMAAFANAARIAIMKEKDLFKFLEELKRCNSGSDSPYSKIPIFPLFPNVD GVVMGKPFKDMQKLEMLRIKEPLHFFEDYFFHKRDWKTQAANIKSMDPAS GYSNNIFTIDQMLKKKQTCTVADATAIKQHVKRATDTYNLGIALEHRKEM LNLWQKIRGDLIGMDSRNESFYDTFSTYTWSWNVCQELLSPKDLRLYDAY VNRNSSHNSRSSSSSDTSECYTDSGRKRKRKGLKGFQQ chromosome location: 62343941-62416479 (17q23.2) Database cross references: | MF: GO:0043169_(0.74)_cation_binding GO:0005509_(0.47)_calcium_ion_binding BP: GO:0019538_(0.58)_protein_metabolic_process GO:0044267_(0.52)_cellular_protein_metabolic process GO:0007165_(0.46)_signal_transduction GO:0050896_(0.43)_response_to_stimulus GO:0035556_(0.43)_intracellular_signal transduction GO:0006796_(0.42)_phosphate-containing_compound metabolic_process GO:0006464_(0.41)_cellular_protein_modification process GO:0051179_(0.40)_localization GO:0006468_(0.40)_protein_phosphorylation GO:0046777_(0.39)_protein_autophosphorylation GO:0042221_(0.39)_response_to_chemical GO:0018105_(0.39)_peptidyl-serine_phosphorylation GO:0051234_(0.38)_establishment_of_localization GO:0010038_(0.37)_response_to_metal_ion GO:0009738_(0.34)_abscisic_acid-activated signaling_pathway CC: GO:0016020_(0.82)_membrane GO:0005737_(0.68)_cytoplasm GO:0005886_(0.66)_plasma_membrane GO:0005634_(0.62)_nucleus GO:0043234_(0.45)_protein_complex GO:0044459_(0.44)_plasma_membrane_part GO:0005829_(0.39)_cytosol GO:0044430_(0.38)_cytoskeletal_part GO:0097458_(0.33)_neuron_part GO:0031090_(0.31)_organelle_membrane | UniProt annotation: GO:0005509_calcium_ion_binding GO:0046872_metal_ion_binding UniProt annotation score: ◉◉○○○ NextProt annotation: GO:0005509_calcium_ion_binding | ||
45 | >NX_Q96GE4-1|CEP95_HUMAN Centrosomal protein of 95 kDa GN=CEP95 MAGSDAEWVTIANNLLFKCHIHLRIHELQDCDANVFIALYQSILGEKVPD LIVIPRSQEDDAHNVQAVIDSLALDYLQVSLSHITGENIVKGDKESIKNL LEIFDGLLEYLTERISETSHEKSETEQYFKESDRGERLEEPESTKESKSS WKRVSFGRCSLSSEMLGPSWDGDEAESTGEIIRLGDTAHTFSLRSNGAQC PNEMLSKKALASPSSKSHEDMLYPPSVLSKSRTSFVEDTETLSVSGIPNA RKLGEPIRAAIPLHPPYHPSEPRAPCPIGKEYLHSSHCSPAVNSTGEHTE FSGDLDDGLFLISKLPKGSKWEVYPAQVQGPRTRKPPKGKRNENRATASS CNSPFPQRPRKRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDH KEENTGNEEVEDGTEETLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSL SPSPVNKHKQFHLERKRQRKPRETDVRQFQAQAFTEAFERELRRHKVQEN IGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKTTTQSLRGGLP KPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKE ACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQR LTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGL NIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQE HQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELE AERFRSRLQLASFQYSKSPSL chromosome location: 64506588-64542461 (17q23.3) Database cross references: | MF: GO:0035639_(0.32)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.32)_adenyl_ribonucleotide_binding GO:0032550_(0.32)_purine_ribonucleoside_binding GO:0003676_(0.32)_nucleic_acid_binding BP: GO:0016043_(0.38)_cellular_component_organization CC: GO:0005813_(1.00)_centrosome GO:0000922_(1.00)_spindle_pole | UniProt annotation: GO:0005813_centrosome GO:0000922_spindle_pole GO:0005515_protein_binding GO:0005815_microtubule_organizing_center GO:0005737_cytoplasm GO:0005856_cytoskeleton UniProt annotation score: ◉◉◉◉○ NextProt annotation: GO:0005515_protein_binding | High: glandular_cells) | |
46 | >NX_O60309-1|L37A3_HUMAN Leucine-rich repeat-containing protein 37A3 GN=LRRC37A3 MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLT SNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQ ESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKL KKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELR VKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLL EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP MEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHH QTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVE PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAA EHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG FTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ VQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTL PPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPD LGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPA QDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQ RLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVIT ELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLV PLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSAC LTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINL SGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNS LAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENT AEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKP FSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVH SRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSL INSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEEN VFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNV GTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRT LKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTEN YINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLC LIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP chromosome location: 64854312-64919480 (17q24.1) Database cross references: | BP: GO:0007165_(0.47)_signal_transduction GO:0032502_(0.45)_developmental_process GO:0044767_(0.44)_single-organism_developmental process GO:0016043_(0.35)_cellular_component_organization GO:0048583_(0.34)_regulation_of_response_to stimulus GO:0007166_(0.32)_cell_surface_receptor_signaling pathway GO:0009653_(0.31)_anatomical_structure morphogenesis CC: GO:0005737_(0.38)_cytoplasm | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ NextProt annotation: | High: early_spermatids) spermatocytes) | |
47 | >NX_Q2M2W7-1|CQ058_HUMAN UPF0450 protein C17orf58 GN=C17orf58 MNRLYLTPDGFFFRVHMLALDSSSCNKPCPEFKPGSRYIVMGHIYHKRRQ LPTALLQVLRGRLRPGDGLLRSSSSYVKRFNRKREGQIQGAIHTQCI chromosome location: 67991101-67996431 (17q24.2) Database cross references: | BP: GO:0052548_(0.37)_regulation_of_endopeptidase activity GO:0010466_(0.37)_negative_regulation_of_peptidase activity CC: GO:0005615_(0.67)_extracellular_space GO:0005576_(0.67)_extracellular_region GO:0031988_(0.60)_membrane-bounded_vesicle GO:0070062_(0.53)_extracellular_exosome GO:0016020_(0.33)_membrane | UniProt annotation: UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
48 | >NX_Q969W3-1|F104A_HUMAN FAM104A GN=FAM104A MGGRGADAGSSGGTGPTEGYSPPAASTRAAARAKARGGGRGGRRNTTPSV PSLRGAAPRSFHPPAAMSERLRPRKRRRNGNEEDNHLPPQTKRSSRNPVF QDSWDTESSGSDSGGSSSSSSSSINSPDRASGPEGSLSQTMAGSSPNTPQ PVPEQSALCQGLYFHINQTLREAHFHSLQHRGRPLT chromosome location: 73207353-73236753 (17q25.1) Database cross references: | BP: GO:0006950_(0.81)_response_to_stress GO:0042276_(0.80)_error-prone_translesion synthesis CC: GO:0043234_(0.85)_protein_complex GO:0005634_(0.84)_nucleus GO:0061695_(0.81)_transferase_complex, transferring_phosphorus-containing_groups GO:0016035_(0.80)_zeta_DNA_polymerase_complex GO:0005829_(0.68)_cytosol GO:0016020_(0.57)_membrane GO:0005737_(0.57)_cytoplasm GO:0031982_(0.51)_vesicle GO:0005886_(0.51)_plasma_membrane GO:0043232_(0.45)_intracellular_non-membrane- bounded_organelle GO:0031410_(0.45)_cytoplasmic_vesicle GO:0030054_(0.45)_cell_junction GO:0044459_(0.40)_plasma_membrane_part GO:0031988_(0.40)_membrane-bounded_vesicle GO:0005773_(0.40)_vacuole | UniProt annotation: GO:0005515_protein_binding UniProt annotation score: ◉◉○○○ NextProt annotation: GO:0005515_protein_binding | ||
49 | >NX_Q9BSJ5-1|CQ080_HUMAN Uncharacterized protein C17orf80 GN=C17orf80 MSDNPPRMEVCPYCKKPFKRLKSHLPYCKMIGPTIPTDQKVYQSKPATLP RAKKMKGPIKDLIKAKGKELETENEERNSKLVVDKPEQTVKTFPLPAVGL ERAATTKADKDIKNPIQPSFKMLKNTKPMTTFQEETKAQFYASEKTSPKR ELAKDLPKSGESRCNPSEAGASLLVGSIEPSLSNQDRKYSSTLPNDVQTT SGDLKLDKIDPQRQELLVKLLDVPTGDCHISPKNVSDGVKRVRTLLSNER DSKGRDHLSGVPTDVTVTETPEKNTESLILSLKMSSLGKIQVMEKQEKGL TLGVETCGSKGNAEKSMSATEKQERTVMSHGCENFNTRDSVTGKESQGER PHLSLFIPRETTYQFHSVSQSSSQSLASLATTFLQEKKAEAQNHHCVPDV KALMESPEGQLSLEPKSDSQFQASHTGCQSPLCSAQRHTPQSPFTNHAAA AGRKTLRSCMGLEWFPELYPGYLGLGVLPGKPQCWNAMTQKPQLISPQGE RLSQVSLLERSSTHIRSLEPPAGLTTSNFSLMRLLGAVQKGWIRCNTTIR KSGFGGITMLFTGYFVLCCSWSFRRLKKLCRPLPWKSTVPPCIGVAKTTG DCRSKTCLD chromosome location: 73232233-73248947 (17q25.1) Database cross references: | MF: GO:1901363_(0.43)_heterocyclic_compound_binding GO:0097159_(0.43)_organic_cyclic_compound_binding GO:0097367_(0.40)_carbohydrate_derivative_binding GO:0035639_(0.39)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.39)_adenyl_ribonucleotide_binding GO:0032550_(0.39)_purine_ribonucleoside_binding GO:0008092_(0.35)_cytoskeletal_protein_binding GO:0003676_(0.35)_nucleic_acid_binding BP: GO:0032501_(0.47)_multicellular_organismal_process GO:0044767_(0.46)_single-organism_developmental process GO:0016043_(0.46)_cellular_component_organization GO:0065008_(0.44)_regulation_of_biological_quality GO:0044707_(0.37)_single-multicellular_organism process GO:0006996_(0.33)_organelle_organization CC: GO:0070062_(0.97)_extracellular_exosome | UniProt annotation: GO:0070062_extracellular_exosome GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ NextProt annotation: | ||
50 | >NX_Q7RTS6-1|OTOP2_HUMAN Otopetrin-2 GN=OTOP2 MSEELAQGPKESPPAPRAGPREVWKKGGRLLSVLLAVNVLLLACTLISGG AFNKVAVYDTDVFALLTAMMLLATLWILFYLLRTVRCPCAVPYRDAHAGP IWLRGGLVLFGICTLIMDVFKTGYYSSFFECQSAIKILHPLIQAVFVIIQ TYFLWVSAKDCVHVHLDLTWCGLMFTLTTNLAIWMAAVVDESVHQSHSYS SSHSNASHARLISDQHADNPVGGDSCLCSTAVCQIFQQGYFYLYPFNIEY SLFASTMLYVMWKNVGRFLASTPGHSHTPTPVSLFRETFFAGPVLGLLLF VVGLAVFIIYEVQVSGDGSRTRQALVIYYSFNIVCLGLTTLVSLSGSIIY RFDRRAMDHHKNPTRTLDVALLMGAALGQYAISYYSIVAVVAGTPQDLLA GLNLTHALLMIAQHTFQNMFIIESLHRGPPGAEPHSTHPKEPCQDLTFTN LDALHTLSACPPNPGLVSPSPSDQREAVAIVSTPRSQWRRQCLKDISLFL LLCNVILWIMPAFGARPHFSNTVEVDFYGYSLWAVIVNICLPFGIFYRMH AVSSLLEVYVLS chromosome location: 74924275-74933912 (17q25.1) Database cross references: | MF: GO:0046983_(0.55)_protein_dimerization_activity GO:0046873_(0.55)_metal_ion_transmembrane transporter_activity GO:0042802_(0.55)_identical_protein_binding GO:0031420_(0.55)_alkali_metal_ion_binding GO:0015077_(0.55)_monovalent_inorganic_cation transmembrane_transporter_activity GO:0009678_(0.39)_hydrogen-translocating pyrophosphatase_activity GO:0004427_(0.39)_inorganic_diphosphatase_activity BP: GO:0042472_(1.00)_inner_ear_morphogenesis GO:0009590_(0.51)_detection_of_gravity GO:0045299_(0.49)_otolith_mineralization GO:0032475_(0.49)_otolith_formation GO:0098662_(0.41)_inorganic_cation_transmembrane transport GO:0030001_(0.41)_metal_ion_transport CC: GO:0016020_(0.86)_membrane GO:0016021_(0.61)_integral_component_of_membrane GO:0005886_(0.35)_plasma_membrane GO:0043234_(0.31)_protein_complex | UniProt annotation: Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. {ECO:0000250|UniProtKB:Q80SX5}. GO:1902600_proton_transmembrane_transport GO:0015252_proton_channel_activity GO:0005886_plasma_membrane GO:0016020_membrane GO:0006811_ion_transport GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
51 | >NX_Q86X02-1|CDR2L_HUMAN Cerebellar degeneration-related protein 2-like GN=CDR2L MRRAAGMEDFSAEEEESWYDQQDLEQDLHLAAELGKTLLERNKELEGSLQ QMYSTNEEQVQEIEYLTKQLDTLRHVNEQHAKVYEQLDLTARDLELTNHR LVLESKAAQQKIHGLTETIERLQAQVEELQAQVEQLRGLEQLRVLREKRE RRRTIHTFPCLKELCTSPRCKDAFRLHSSSLELGPRPLEQENERLQTLVG ALRSQVSQERQRKERAEREYTAVLQEYSELERQLCEMEACRLRVQELEAE LLELQQMKQAKTYLLGPDDHLAEALLAPLTQAPEADDPQPGRGDDLGAQD GVSSPAASPGHVVRKSCSDTALNAIVAKDPASRHAGNLTLHANSVRKRGM SILREVDEQYHALLEKYEELLSKCRQHGAGVRHAGVQTSRPISRDSSWRD LRGGEEGQGEVKAGEKSLSQHVEAVDKRLEQSQPEYKALFKEIFSRIQKT KADINATKVKTHSSK chromosome location: 74987632-75005800 (17q25.1) Database cross references: | MF: GO:0016787_(0.46)_hydrolase_activity GO:0017111_(0.45)_nucleoside-triphosphatase activity GO:0008092_(0.37)_cytoskeletal_protein_binding GO:1901363_(0.35)_heterocyclic_compound_binding GO:0097159_(0.35)_organic_cyclic_compound_binding GO:0035639_(0.33)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.33)_adenyl_ribonucleotide_binding GO:0032550_(0.33)_purine_ribonucleoside_binding BP: GO:0016043_(0.52)_cellular_component_organization GO:0006996_(0.44)_organelle_organization GO:0022607_(0.37)_cellular_component_assembly GO:0007010_(0.36)_cytoskeleton_organization GO:0070925_(0.33)_organelle_assembly GO:0043933_(0.31)_macromolecular_complex_subunit organization CC: GO:0044430_(0.87)_cytoskeletal_part GO:0005737_(0.80)_cytoplasm GO:0043234_(0.64)_protein_complex GO:0043232_(0.61)_intracellular_non-membrane- bounded_organelle GO:0016459_(0.54)_myosin_complex GO:0016020_(0.49)_membrane GO:0042995_(0.32)_cell_projection GO:0032982_(0.31)_myosin_filament | UniProt annotation: GO:0005515_protein_binding UniProt annotation score: ◉◉◉○○ NextProt annotation: GO:0005515_protein_binding | High: cells) epithelial_cells) nerve/ganglion) | |
52 | >NX_Q12767-1|TMM94_HUMAN Transmembrane protein 94 GN=TMEM94 MDLKEKHLGEPPSALGLSTRKALSVLKEQLEAVLEGHLRERKKCLTWKEV WRSSFLHHSNRCSCFHWPGASLMLLAVLLLLGCCGGQPAGSRGVGLVNAS ALFLLLLLNLVLIGRQDRLKRREVERRLRGIIDQIQDALRDGREIQWPSA MYPDLHMPFAPSWSLHWAYRDGHLVNLPVSLLVEGDIIALRPGQESFASL RGIKDDEHIVLEPGDLFPPFSPPPSPRGEVERGPQSPQQHRLFRVLETPV IDNIRWCLDMALSRPVTALDNERFTVQSVMLHYAVPVVLAGFLITNALRF IFSAPGVTSWQYTLLQLQVNGVLPILPLLFPVLWVLATACGEARVLAQMS KASPSSLLAKFSEDTLSSYTEAVSSQEMLRCIWGHFLRVLGGTSPTLSHS SSLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPPHSSHEDLT DGLSTRSFCHPEPHERDALLAGSLNNTLHLSNEQERGDWPGEAPKPPEPY SHHKAHGRSKHPSGSNVSFSRDTEGGEEEPSKTQPGMESDPYEAEDFVCD YHLEMLSLSQDQQNPSCIQFDDSNWQLHLTSLKPLGLNVLLNLCDASVTE RLCRFSDHLCNIALQESHSAVLPVHVPWGLCELARLIGFTPGAKELFKQE NHLALYRLPSAETMKETSLGRLSCVTKRRPPLSHMISLFIKDTTTSTEQM LSHGTADVVLEACTDFWDGADIYPLSGSDRKKVLDFYQRACLSGYCSAFA YKPMNCALSSQLNGKCIELVQVPGQSSIFTMCELPSTIPIKQNARRSSWS SDEGIGEVLEKEDCMQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIR FVYFSLEDELKSKVFAEKMGLETGWNCHISLTPNGDMPGSEIPPSSPSHA GSLHDDLNQVSRDDAEGLLLMEEEGHSDLISFQPTDSDIPSFLEDSNRAK LPRGIHQVRPHLQNIDNVPLLVPLFTDCTPETMCEMIKIMQEYGEVTCCL GSSANLRNSCLFLQSDISIALDPLYPSRCSWETFGYATSISMAQASDGLS PLQLSGQLNSLPCSLTFRQEETISIIRLIEQARHATYGIRKCFLFLLQCQ LTLVVIQFLSCLVQLPPLLSTTDILWLSCFCYPLLSISLLGKPPHSSIMS MATGKNLQSIPKKTQHYFLLCFLLKFSLTISSCLICFGFTLQSFCDSSRD RNLTNCSSVMLPSNDDRAPAWFEDFANGLLSAQKLTAALIVLHTVFISIT HVHRTKPLWRKSPLTNLWWAVTVPVVLLGQVVQTAVDLQLWTHRDSHVHF GLEDVPLLTWLLGCLSLVLVVVTNEIVKLHEIRVRVRYQKRQKLQFETKL GMNSPF chromosome location: 75441159-75500090 (17q25.1) Database cross references: | MF: GO:0043492_(0.91)_ATPase_activity,_coupled_to movement_of_substances GO:0022892_(0.91)_substrate-specific_transporter activity GO:0019829_(0.74)_cation-transporting_ATPase activity GO:0022890_(0.61)_inorganic_cation_transmembrane transporter_activity GO:0015662_(0.61)_ATPase_activity,_coupled_to transmembrane_movement_of_ions,_phosphorylative mechanism GO:0046873_(0.57)_metal_ion_transmembrane transporter_activity GO:0015077_(0.41)_monovalent_inorganic_cation transmembrane_transporter_activity GO:0005524_(0.37)_ATP_binding GO:0005391_(0.37)_sodium:potassium-exchanging ATPase_activity BP: GO:0065008_(0.80)_regulation_of_biological_quality GO:0098771_(0.77)_inorganic_ion_homeostasis GO:0030003_(0.77)_cellular_cation_homeostasis GO:0006875_(0.72)_cellular_metal_ion_homeostasis GO:0006810_(0.71)_transport GO:0006812_(0.68)_cation_transport GO:0034220_(0.66)_ion_transmembrane_transport GO:0098662_(0.65)_inorganic_cation_transmembrane transport GO:1902600_(0.64)_hydrogen_ion_transmembrane transport GO:0090662_(0.60)_ATP_hydrolysis_coupled transmembrane_transport GO:0015988_(0.60)_energy_coupled_proton transmembrane_transport,_against_electrochemical gradient GO:0030004_(0.57)_cellular_monovalent_inorganic cation_homeostasis GO:0030001_(0.56)_metal_ion_transport GO:0071805_(0.52)_potassium_ion_transmembrane transport GO:0071436_(0.52)_sodium_ion_export CC: GO:0005654_(1.00)_nucleoplasm | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ NextProt annotation: | High: | |
53 | >NX_Q8WXE0-1|CSKI2_HUMAN Caskin-2 GN=CASKIN2 MGREQDLILAVKNGDVTGVQKLVAKVKATKTKLLGSTKRLNVNYQDADGF SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRL LLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKT PLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNG HREVIRQLLRAGIEINRQTKTGTALHEAALYGKTEVVRLLLEGGVDVNIR NTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDFWNLHDPTA LNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVG IPAARLPSAPTPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGD RNSVGSEGSVGSIRSAGSGQSSEGTNGHGPGLLIENAQPLPSAGEDQVLP GLHPPSLADNLSHRPLANCRSGEQIFTQDVRPEQLLEGKDAQAIHNWLSE FQLEGYTAHFLQAGYDVPTISRMTPEDLTAIGVTKPGHRKKIASEIAQLS IAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLTWEELQE IGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEG LENGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQES IGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQG PPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHS LSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPA RGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGAT GPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGL PFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCRERE PLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVP TPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGT APKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQAQQRLEQ TSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTMFDALADQLDAM LD chromosome location: 75500261-75515583 (17q25.1) Database cross references: | MF: GO:0016740_(0.39)_transferase_activity GO:0019899_(0.31)_enzyme_binding BP: GO:0007165_(0.41)_signal_transduction CC: GO:0005737_(0.60)_cytoplasm GO:0005634_(0.36)_nucleus | UniProt annotation: GO:0016020_membrane GO:0005737_cytoplasm UniProt annotation score: ◉◉◉○○ NextProt annotation: | High: peripheral_nerve/ganglion) cells) | |
54 | >NX_Q71RC9-1|SMIM5_HUMAN Small integral membrane protein 5 GN=SMIM5 MAATDFVQEMRAVGERLLLKLQRLPQAEPVEIVAFSVIILFTATVLLLLL IACSCCCTHCCCPERRGRKVQVQPTPP chromosome location: 75633434-75641404 (17q25.1) Database cross references: | MF: GO:0051015_(0.33)_actin_filament_binding GO:0030274_(0.33)_LIM_domain_binding GO:0017166_(0.33)_vinculin_binding GO:0005200_(0.33)_structural_constituent_of cytoskeleton GO:0005178_(0.33)_integrin_binding BP: GO:0098876_(0.48)_vesicle-mediated_transport_to the_plasma_membrane GO:0071702_(0.48)_organic_substance_transport GO:0051278_(0.48)_fungal-type_cell_wall polysaccharide_biosynthetic_process GO:0045184_(0.48)_establishment_of_protein localization GO:0030010_(0.48)_establishment_of_cell_polarity GO:0006892_(0.48)_post-Golgi_vesicle-mediated transport GO:0006038_(0.48)_cell_wall_chitin_biosynthetic process GO:0000281_(0.48)_mitotic_cytokinesis GO:0070527_(0.33)_platelet_aggregation GO:0030866_(0.33)_cortical_actin_cytoskeleton organization GO:0007044_(0.33)_cell-substrate_junction_assembly GO:0007016_(0.33)_cytoskeletal_anchoring_at_plasma membrane CC: GO:0016020_(0.93)_membrane GO:0043234_(0.60)_protein_complex GO:0044431_(0.53)_Golgi_apparatus_part GO:0005794_(0.53)_Golgi_apparatus GO:0031988_(0.47)_membrane-bounded_vesicle GO:0005737_(0.47)_cytoplasm GO:0070062_(0.40)_extracellular_exosome GO:0044430_(0.40)_cytoskeletal_part GO:0034044_(0.40)_exomer_complex GO:0005925_(0.40)_focal_adhesion GO:0005886_(0.40)_plasma_membrane GO:0005856_(0.40)_cytoskeleton GO:0032587_(0.33)_ruffle_membrane GO:0009986_(0.33)_cell_surface GO:0005815_(0.33)_microtubule_organizing_center | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ NextProt annotation: | High: cells) center_cells;_squamous_epithelial_cells) glandular_cells) glandular_cells) Langerhans) cells;_neuronal_cells) | |
55 | >NX_Q96LD4-1|TRI47_HUMAN Tripartite motif-containing protein 47 GN=TRIM47 MDGSGPFSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGG AARCPLCQEPFPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPS APSALPSVPEPSAPCAPEPWPAGEEPVRCDACPEGAALPAALSCLSCLAS FCPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLRPLERYCRAERVCL CEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSR RTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRS QGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPG PGPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSE ADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKGVK RVLCPINYPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGWVSMGVMAE DFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVGV CLEYADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSH FAGLFTHRLKPAFFLESVDAHLQIGPLKKSCISVLKRR chromosome location: 75874161-75878575 (17q25.1) Database cross references: | MF: GO:0004842_(0.76)_ubiquitin-protein_transferase activity GO:0061630_(0.31)_ubiquitin_protein_ligase activity BP: GO:0031323_(0.54)_regulation_of_cellular_metabolic process GO:0019538_(0.54)_protein_metabolic_process GO:0060255_(0.53)_regulation_of_macromolecule metabolic_process GO:0080090_(0.52)_regulation_of_primary_metabolic process GO:0048518_(0.50)_positive_regulation_of biological_process GO:0006464_(0.50)_cellular_protein_modification process GO:0032446_(0.48)_protein_modification_by_small protein_conjugation GO:0048522_(0.47)_positive_regulation_of_cellular process GO:0016567_(0.47)_protein_ubiquitination GO:0065008_(0.46)_regulation_of_biological_quality GO:0044764_(0.46)_multi-organism_cellular_process GO:0051715_(0.43)_cytolysis_in_other_organism GO:0010468_(0.41)_regulation_of_gene_expression GO:2001141_(0.40)_regulation_of_RNA_biosynthetic process GO:2000112_(0.40)_regulation_of_cellular macromolecule_biosynthetic_process CC: GO:0005737_(0.57)_cytoplasm GO:0016020_(0.41)_membrane GO:0005634_(0.41)_nucleus GO:0005576_(0.41)_extracellular_region GO:0043232_(0.38)_intracellular_non-membrane- bounded_organelle GO:0043234_(0.35)_protein_complex GO:0044428_(0.32)_nuclear_part | UniProt annotation: GO:0005829_cytosol GO:0008270_zinc_ion_binding GO:0005622_intracellular GO:0046872_metal_ion_binding GO:0005737_cytoplasm GO:0005634_nucleus UniProt annotation score: ◉◉◉◉○ NextProt annotation: GO:0008270_zinc_ion_binding | ||
56 | >NX_Q8IYN6-1|UBAD2_HUMAN UBA-like domain-containing protein 2 GN=UBALD2 MSVNMDELRHQVMINQFVLAAGCAADQAKQLLQAAHWQFETALSTFFQET NIPNSHHHHQMMCTPSNTPATPPNFPDALAMFSKLRASEGLQSSNSPMTA AACSPPANFSPFWASSPPSHQAPWIPPSSPTTFHHLHRPQPTWPPGAQQG GAQQKAMAAMDGQR chromosome location: 76265202-76271299 (17q25.1) Database cross references: | MF: GO:1901363_(0.46)_heterocyclic_compound_binding GO:0097159_(0.46)_organic_cyclic_compound_binding GO:0043169_(0.41)_cation_binding GO:0016491_(0.40)_oxidoreductase_activity GO:0046906_(0.39)_tetrapyrrole_binding GO:0016684_(0.39)_oxidoreductase_activity,_acting on_peroxide_as_acceptor GO:0016209_(0.39)_antioxidant_activity BP: GO:0044248_(0.53)_cellular_catabolic_process GO:0050896_(0.44)_response_to_stimulus GO:0044710_(0.41)_single-organism_metabolic process GO:0006950_(0.41)_response_to_stress GO:1990748_(0.39)_cellular_detoxification GO:0042743_(0.39)_hydrogen_peroxide_metabolic process GO:0016043_(0.38)_cellular_component_organization CC: GO:0005576_(0.55)_extracellular_region GO:0043234_(0.44)_protein_complex GO:0005634_(0.43)_nucleus GO:0044428_(0.42)_nuclear_part GO:0044451_(0.36)_nucleoplasm_part GO:0005737_(0.31)_cytoplasm | UniProt annotation: UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
57 | >NX_Q9H0J4-1|QRIC2_HUMAN Glutamine-rich protein 2 GN=QRICH2 MKDAAEELSFARVLLQRVDELEKLFKDREQFLELVSRKLSLVPGAEEVTM VTWEELEQAITDGWRASQAGSETLMGFSKHGGFTSLTSPEGTLSGDSTKQ PSIEQALDSASGLGPDRTASGSGGTAHPSDGVSSREQSKVPSGTGRQQQP RARDEAGVPRLHQSSTFQFKSDSDRHRSREKLTSTQPRRNARPGPVQQDL PLARDQPSSVPASQSQVHLRPDRRGLEPTGMNQPGLVPASTYPHGVVPLS MGQLGVPPPEMDDRELIPFVVDEQRMLPPSVPGRDQQGLELPSTDQHGLV SVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQGLVPPGIDQQGLT LPVVDQHGLVLPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPGTE QHDLIQSGRFQRALVQRGAYQPGLVQPGADQRGLVRPGMDQSGLAQPGAD QRGLVWPGMDQSGLAQPGRDQHGLIQPGTGQHDLVQSGTGQGVLVQPGVD QPGMVQPGRFQRALVQPGAYQPGLVQPGADQIDVVQPGADQHGLVQSGAD QSDLAQPGAVQHGLVQPGVDQRGLAQPRADHQRGLVPPGADQRGLVQPGA DQHGLVQPGVDQHGLAQPGEVQRSLVQPGIVQRGLVQPGAVQRGLVQPGA VQRGLVQPGVDQRGLVQPGAVQRGLVQPGAVQHGLVQPGADQRGLVQPGV DQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQPGAGQLGMVQPGI GQQGMVQPQADPHGLVQPGAYPLGLVQPGAYLHDLSQSGTYPRGLVQPGM DQYGLRQPGAYQPGLIAPGTKLRGSSTFQADSTGFISVRPYQHGMVPPGR EQYGQVSPLLASQGLASPGIDRRSLVPPETYQQGLMHPGTDQHSPIPLST GLGSTHPDQQHVASPGPGEHDQVYPDAAQHGHAFSLFDSHDSMYPGYRGP GYLSADQHGQEGLDPNRTRASDRHGIPAQKAPGQDVTLFRSPDSVDRVLS EGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKD LDEEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAK VERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQ DRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAH TLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKA KLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQ GLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQFDATTEQLNHMMQE LVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDPVKQLLEDRWKSLRQQL RERPPLYQADEAAAMRRQLLAHFHCLSCDRPLETPVTGHAIPVTPAGPGL PGHHSIRPYTVFELEQVRQHSRNLKLGSAFPRGDLAQMEQSVGRLRSMHS KMLMNIEKVQIHFGGSTKASSQIIRELLHAQCLGSPCYKRVTDMADYTYS TVPRRCGGSHTLTYPYHRSRPQHLPRGLYPTEEIQIAMKHDEVDILGLDG HIYKGRMDTRLPGILRKDSSGTSKRKSQQPRPHVHRPPSLSSNGQLPSRP QSAQISAGNTSER chromosome location: 76274049-76307998 (17q25.1) Database cross references: | BP: GO:0016043_(0.43)_cellular_component_organization GO:0006996_(0.31)_organelle_organization CC: GO:0044430_(0.40)_cytoskeletal_part GO:0043234_(0.36)_protein_complex | UniProt annotation: UniProt annotation score: ◉◉◉○○ NextProt annotation: | High: | |
58 | >NX_P84157-1|MXRA7_HUMAN Matrix-remodeling-associated protein 7 GN=MXRA7 MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEA TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAA APAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRG NQYKKMMTKEELEEEQRVQKEQLAAIFKLMKDNKETFGEMSDGDVQEQLR LYDM chromosome location: 76672551-76711016 (17q25.1) Database cross references: | MF: GO:0003676_(0.40)_nucleic_acid_binding BP: GO:0050896_(0.43)_response_to_stimulus GO:0051716_(0.37)_cellular_response_to_stimulus GO:0006950_(0.31)_response_to_stress CC: GO:0005634_(0.59)_nucleus GO:0044428_(0.53)_nuclear_part | UniProt annotation: GO:0031012_extracellular_matrix GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ NextProt annotation: | ||
59 | >NX_O43934-1|MFS11_HUMAN UNC93-like protein MFSD11 GN=MFSD11 MSPESKKLFNIIILGVAFMFMFTAFQTCGNVAQTVIRSLNRTDFHGSGYT SMAIIYGVFSASNLITPSVVAIVGPQLSMFASGLFYSMYIAVFIQPFPWS FYTASVFIGIAAAVLWTAQGNCLTINSDEHSIGRNSGIFWALLQSSLFFG NLYIYFAWQGKTQISESDRRTVFIALTVISLVGTVLFFLIRKPDSENVLG EDESSDDQDMEVNESAQNNLTKAVDAFKKSFKLCVTKEMLLLSITTAYTG LELTFFSGVYGTCIGATNKFGAEEKSLIGLSGIFIGIGEILGGSLFGLLS KNNRFGRNPVVLLGILVHFIAFYLIFLNMPGDAPIAPVKGTDSSAYIKSS KEVAILCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAIFKFVQSICAA VAFFYSNYLLLHWQLLVMVIFGFFGTISFFTVEWEAAAFVARGSDYRSI chromosome location: 76735865-76781449 (17q25.1) Database cross references: | MF: GO:0005215_(0.85)_transporter_activity GO:0022857_(0.84)_transmembrane_transporter activity GO:0022892_(0.78)_substrate-specific_transporter activity GO:0022891_(0.77)_substrate-specific_transmembrane transporter_activity GO:0051119_(0.74)_sugar_transmembrane_transporter activity GO:0015145_(0.72)_monosaccharide_transmembrane transporter_activity GO:0015149_(0.71)_hexose_transmembrane_transporter activity GO:0005355_(0.70)_glucose_transmembrane transporter_activity GO:0008324_(0.67)_cation_transmembrane_transporter activity GO:0005351_(0.66)_sugar:proton_symporter_activity GO:0051183_(0.34)_vitamin_transporter_activity GO:0048029_(0.33)_monosaccharide_binding GO:0015146_(0.33)_pentose_transmembrane transporter_activity GO:0015148_(0.32)_D-xylose_transmembrane transporter_activity BP: GO:0006810_(0.82)_transport GO:0071702_(0.70)_organic_substance_transport GO:0055085_(0.69)_transmembrane_transport GO:0008643_(0.68)_carbohydrate_transport GO:0015749_(0.67)_monosaccharide_transport GO:0008645_(0.66)_hexose_transport GO:0015758_(0.64)_glucose_transport GO:0034219_(0.61)_carbohydrate_transmembrane transport GO:0035428_(0.60)_hexose_transmembrane_transport GO:0046323_(0.47)_glucose_import GO:0050896_(0.38)_response_to_stimulus GO:0006820_(0.38)_anion_transport GO:0051716_(0.35)_cellular_response_to_stimulus GO:0042221_(0.34)_response_to_chemical GO:1901700_(0.33)_response_to_oxygen-containing compound CC: GO:0016021_(1.00)_integral_component_of_membrane GO:0016020_(1.00)_membrane GO:0005887_(0.77)_integral_component_of_plasma membrane GO:0005886_(0.70)_plasma_membrane | UniProt annotation: GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉◉○○ NextProt annotation: | ||
60 | >NX_Q6UX52-1|CQ099_HUMAN Uncharacterized protein C17orf99 GN=C17orf99 MGLPGLFCLAVLAASSFSKAREEEITPVVSIAYKVLEVFPKGRWVLITCC APQPPPPITYSLCGTKNIKVAKKVVKTHEPASFNLNVTLKSSPDLLTYFC WASSTSGAHVDSARLQMHWELWSKPVSELRANFTLQDRGAGPRVEMICQA SSGSPPITNSLIGKDGQVHLQQRPCHRQPANFSFLPSQTSDWFWCQAANN ANVQHSALTVVPPGGDQKMEDWQGPLESPILALPLYRSTRRLSEEEFGGF RIGNGEVRGRKAAAM chromosome location: 78146353-78166177 (17q25.3) Database cross references: | MF: GO:0004872_(0.63)_receptor_activity GO:0004888_(0.56)_transmembrane_signaling_receptor activity GO:0004672_(0.53)_protein_kinase_activity GO:0019199_(0.50)_transmembrane_receptor_protein kinase_activity GO:0097367_(0.49)_carbohydrate_derivative_binding GO:0035639_(0.47)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.47)_adenyl_ribonucleotide_binding GO:0032550_(0.47)_purine_ribonucleoside_binding GO:0046983_(0.39)_protein_dimerization_activity BP: GO:0032502_(0.68)_developmental_process GO:0044767_(0.67)_single-organism_developmental process GO:0048869_(0.61)_cellular_developmental_process GO:0016043_(0.61)_cellular_component_organization GO:0009653_(0.60)_anatomical_structure morphogenesis GO:0006928_(0.58)_movement_of_cell_or_subcellular component GO:0048856_(0.54)_anatomical_structure_development GO:0030030_(0.54)_cell_projection_organization GO:0032989_(0.53)_cellular_component_morphogenesis GO:0048812_(0.52)_neuron_projection_morphogenesis GO:0016477_(0.52)_cell_migration GO:0006796_(0.51)_phosphate-containing_compound metabolic_process GO:0006464_(0.51)_cellular_protein_modification process GO:0016310_(0.50)_phosphorylation GO:0061564_(0.48)_axon_development CC: GO:0031224_(1.00)_intrinsic_component_of_membrane GO:0016020_(1.00)_membrane GO:0016021_(0.95)_integral_component_of_membrane GO:0005886_(0.90)_plasma_membrane GO:0044459_(0.75)_plasma_membrane_part GO:0005887_(0.63)_integral_component_of_plasma membrane GO:0031982_(0.42)_vesicle GO:0097458_(0.41)_neuron_part GO:0042995_(0.40)_cell_projection GO:0031988_(0.38)_membrane-bounded_vesicle GO:0009986_(0.38)_cell_surface GO:0043005_(0.35)_neuron_projection GO:0030054_(0.35)_cell_junction GO:0030424_(0.34)_axon GO:0044421_(0.32)_extracellular_region_part | UniProt annotation: GO:0002313_mature_B_cell_differentiation_involved in_immune_response GO:0005615_extracellular_space GO:2000558_positive_regulation_of_immunoglobulin production_in_mucosal_tissue GO:0005576_extracellular_region UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
61 | >NX_O43760-1|SNG2_HUMAN Synaptogyrin-2 GN=SYNGR2 MESGAYGAAKAGGSFDLRRFLTQPQVVARAVCLVFALIVFSCIYGEGYSN AHESKQMYCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAYFPQISNATD RKYLVIGDLLFSALWTFLWFVGFCFLTNQWAVTNPKDVLVGADSVRAAIT FSFFSIFSWGVLASLAYQRYKAGVDDFIQNYVDPTPDPNTAYASYPGASV DNYQQPPFTQNAETTEGYQPPPVY chromosome location: 78168558-78173527 (17q25.3) Database cross references: | MF: GO:0043169_(0.37)_cation_binding BP: GO:0006810_(0.66)_transport GO:0051649_(0.64)_establishment_of_localization_in cell GO:0051641_(0.64)_cellular_localization GO:0006605_(0.52)_protein_targeting GO:0051049_(0.31)_regulation_of_transport CC: GO:0031594_(1.00)_neuromuscular_junction GO:0030672_(1.00)_synaptic_vesicle_membrane | UniProt annotation: May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane. {ECO:0000250|UniProtKB:O54980}. (Microbial infection) May play a role in the assembly of cytoplasmic inclusion bodies required for SFTS phlebovirus replication. {ECO:0000269|PubMed:27226560}. GO:0030672_synaptic_vesicle_membrane GO:0005515_protein_binding GO:0070062_extracellular_exosome GO:0016021_integral_component_of_membrane GO:0048499_synaptic_vesicle_membrane_organization GO:0045055_regulated_exocytosis GO:0031594_neuromuscular_junction GO:0030054_cell_junction GO:0005811_lipid_droplet GO:0031410_cytoplasmic_vesicle GO:0045202_synapse GO:0016020_membrane GO:0008021_synaptic_vesicle GO:0030659_cytoplasmic_vesicle_membrane UniProt annotation score: ◉◉◉◉◉ NextProt annotation: GO:0045055_regulated_exocytosis GO:0048499_synaptic_vesicle_membrane_organization GO:0005515_protein_binding | High: center_cells;_squamous_epithelial_cells) germinal_center_cells) | |
62 | >NX_Q96MC4-1|C295L_HUMAN CEP295 N-terminal-like protein GN=CEP295NL MCSGWSSSVIWRHTQFAVERCGFCGSSGPGAPLEPSTLGSKHLPWEAVSA GFADRNRNMDGAMWLSLCPDNEDLLWRKKHKLLQARGKGDLALQRRADAK LWKNYQLQRLAEELRRGYQEAQHLHVGGLDRLQSARLLGWGGGRARENEP DSQGPIQRRSARPPRAKEKHRAALSEERSCREELGQQHPRHSRPRKTAAS PEKPQTTKATGRMNSHLAPPEKRKGRPEPSTKSGGGRCAIHPRRSKGADL ERSNPLVAAVGEIGLVEEKEKGTARAGRRQLGKGAVCFVPALTSRSQGQS LEGKLRDLGQLWPADSSCRREAVSPASQCTLREKNKWQKELELAFEELFN INRKLKKHLCLYLALKPRMDQRPGEGHAFSEMQECGAGTPRGKKMADPEM LPAGEPRSPAEEEAQQAASKTDLKTFMGKAQNQKYQGTVKPTFRNGSQTL SPEAGIFINKEDSLLYSTESGQETPKLGTLAEGSLQLHLQDQADRVGSTA SRQRQKAEMEQRRQKQLESLEQMEHPDMSLEIHYKAELEKERREQRRARL AHLKSSSTRAQERERGSELSTTSPSGTSLADDDRHSQMIRDQQQQILQQN RLHKQFLEEARKCLREFQNIC chromosome location: 78870910-78903217 (17q25.3) Database cross references: | MF: GO:0016740_(0.50)_transferase_activity GO:0036094_(0.45)_small_molecule_binding GO:1901981_(0.44)_phosphatidylinositol_phosphate binding GO:0030234_(0.44)_enzyme_regulator_activity GO:0033218_(0.43)_amide_binding GO:0030246_(0.43)_carbohydrate_binding GO:0010485_(0.43)_H4_histone_acetyltransferase activity GO:0008375_(0.43)_acetylglucosaminyltransferase activity BP: GO:0051128_(0.64)_regulation_of_cellular_component organization GO:0048518_(0.63)_positive_regulation_of biological_process GO:0048522_(0.62)_positive_regulation_of_cellular process GO:0033043_(0.61)_regulation_of_organelle organization GO:0010638_(0.58)_positive_regulation_of_organelle organization GO:0016043_(0.55)_cellular_component_organization GO:0032502_(0.51)_developmental_process GO:0044767_(0.49)_single-organism_developmental process GO:0051179_(0.48)_localization GO:0006996_(0.48)_organelle_organization GO:0048856_(0.47)_anatomical_structure_development GO:0065008_(0.44)_regulation_of_biological_quality GO:0051641_(0.44)_cellular_localization GO:0022607_(0.44)_cellular_component_assembly GO:0044267_(0.43)_cellular_protein_metabolic process CC: GO:0043234_(0.63)_protein_complex GO:0044430_(0.58)_cytoskeletal_part GO:0005737_(0.53)_cytoplasm GO:0016020_(0.44)_membrane GO:0005829_(0.43)_cytosol GO:0043232_(0.42)_intracellular_non-membrane- bounded_organelle GO:0044428_(0.33)_nuclear_part GO:0005634_(0.33)_nucleus | UniProt annotation: GO:0005929_cilium GO:0042995_cell_projection UniProt annotation score: ◉◉○○○ NextProt annotation: | ||
63 | >NX_Q96N21-1|AP4AT_HUMAN AP-4 complex accessory subunit Tepsin GN=TEPSIN MAAAPPLRDRLSFLHRLPILLKGTSDDDVPCPGYLFEEIAKISHESPGSS QCLLEYLLSRLHSSSGHGKLKVLKILLYLCSHGSSFFLLILKRNSAFIQE AAAFAGPPDPLHGNSLYQKVRAAAQDLGSTLFSDTVLPLAPSQPLGTPPA TGMGSQARPHSTLQGFGYSKEHGRTAVRHQPGQAGGGWDELDSGPSSQNS SQNSDLSRVSDSGSHSGSDSHSGASREPGDLAERVEVVALSDCQQELSLV RTVTRGPRAFLSREEAQHFIKACGLLNCEAVLQLLTCHLRGTSECTQLRA LCAIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEA SCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVS SRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIP GGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAP QTSSQRTAAKEPPGSEPSAFAFLNA chromosome location: 81228277-81239091 (17q25.3) Database cross references: | MF: GO:0043167_(0.43)_ion_binding GO:0043169_(0.42)_cation_binding CC: GO:0043234_(0.63)_protein_complex GO:0005737_(0.60)_cytoplasm GO:0016020_(0.41)_membrane GO:0044428_(0.38)_nuclear_part GO:0043232_(0.33)_intracellular_non-membrane- bounded_organelle GO:1902494_(0.32)_catalytic_complex GO:1990234_(0.31)_transferase_complex | UniProt annotation: Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network. {ECO:0000305|PubMed:22472443, ECO:0000305|PubMed:26542808}. GO:0030124_AP-4_adaptor_complex GO:0005794_Golgi_apparatus GO:0030662_coated_vesicle_membrane GO:0032588_trans-Golgi_network_membrane GO:0031312_extrinsic_component_of_organelle membrane GO:0005515_protein_binding GO:0005737_cytoplasm GO:0031965_nuclear_membrane GO:0016607_nuclear_speck GO:0031410_cytoplasmic_vesicle GO:0016020_membrane GO:0005829_cytosol UniProt annotation score: ◉◉◉◉◉ NextProt annotation: GO:0005515_protein_binding | ||
64 | >NX_Q5BKU9-1|OXLD1_HUMAN Oxidoreductase-like domain-containing protein 1 GN=OXLD1 MLLRRVVEGGRAVAAAVRGSGARRFSSPDCCQRLPGGGSFLQRHHPGAQA PDGRRKFGTDHVEVGSQAGADGTRPPKASLPPELQPPTNCCMSGCPNCVW VEYADRLLQHFQDGGERALAALEEHVADENLKAFLRMEIRLHTRCGG chromosome location: 81665036-81666635 (17q25.3) Database cross references: | MF: GO:0016491_(0.87)_oxidoreductase_activity GO:0000166_(0.82)_nucleotide_binding GO:0071949_(0.73)_FAD_binding GO:0004128_(0.73)_cytochrome-b5_reductase activity,_acting_on_NAD(P)H GO:0016211_(0.52)_ammonia_ligase_activity GO:0035639_(0.33)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.33)_adenyl_ribonucleotide_binding GO:0032550_(0.33)_purine_ribonucleoside_binding BP: GO:0015701_(0.90)_bicarbonate_transport GO:0009084_(0.53)_glutamine_family_amino_acid biosynthetic_process GO:0008652_(0.53)_cellular_amino_acid_biosynthetic process GO:0006541_(0.53)_glutamine_metabolic_process GO:0071941_(0.34)_nitrogen_cycle_metabolic_process CC: GO:0005739_(0.90)_mitochondrion GO:0005737_(0.66)_cytoplasm | UniProt annotation: UniProt annotation score: ◉○○○○ NextProt annotation: | ||
65 | >NX_Q2TAC2-1|CCD57_HUMAN Coiled-coil domain-containing protein 57 GN=CCDC57 MLPLGSEPALNELLLRKEEEWRALQAHRTQLQEAALQDTRSQLEEAQGKL RCLQEDFVYNLQVLEERDLELERYDAAFAQAREWEEARRAEVSELKIEAA KLRQALAREARKVEELQQQQQLAFQEHRLELERVHSDKNGEIDHHREQYE NLKWTLERKLEELDGELALQRQELLLEFESKMRKREHEFRLQADNMSNTA LSRELKVKLLHKELEALKEAGAKAAESLQRAEATNAELERKLQSRAGELQ DLEAMSRARVKDLEDKLHSVQLTRKKEEETFKRKHEELDRLAREKDAVLV AVKGAHVEQLQELQTRVLELQAHCETLEAQLRRAEWRQADTAKEKDAAID QLREDASTVKSAWDAQIAQLSKEMVSRDLQIQTLQEEEVKLKAQVARSQQ DIERYKQQLSLAVERERSLERDQVQLGLDWQRRCDDIERDQIQKSEALIQ GLSMAKSQVAAKLQETEQALQEQEVVLKAVTLERDQAVQALRMHGLPRPG AQMLLRQHEEEISKDFPSSEIQRLREQNTSLRNAIAQMRKEMEALSHQIP PPIQTAAESTDANQPDPEAGGDAATPDYVLALEAEIRTLKHKFKTLEKHL EDVLDPLKMSSPHAESQPSVRTSTETTGGSAQAGQAGGSVQAGQAGGSVQ AGPVSSGLALRKLGDRVQLLNLLVTRLRQKVLREPLEPAALQRELPREVD QVHLEVLELRKQVAELGKHLRIAQHGGAEPSGRKQPPASDAVALGREQDA KSAEDEAPSRHLGKHQPRSAQVGSRLDALQGPKTQHSIHTVTCKSPRQKE DRSPKPPQAPQHPEEHGRQSHSSSSFASGTLQDMWRLLDLGSSPSGVTSQ GDSTPELPAPPAADRRPVKMQAGIATPGMKTAAQAKAKTTGASRSHPAKA KGCQRPPKIRNYNIMD chromosome location: 82101460-82212830 (17q25.3) Database cross references: | MF: GO:0097367_(0.44)_carbohydrate_derivative_binding GO:0035639_(0.41)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.41)_adenyl_ribonucleotide_binding GO:0032550_(0.41)_purine_ribonucleoside_binding GO:0052813_(0.31)_phosphatidylinositol bisphosphate_kinase_activity GO:0052742_(0.31)_phosphatidylinositol_kinase activity GO:0035004_(0.31)_phosphatidylinositol_3-kinase activity GO:0016307_(0.31)_phosphatidylinositol_phosphate kinase_activity BP: GO:0016043_(0.56)_cellular_component_organization GO:0048518_(0.50)_positive_regulation_of biological_process GO:0060255_(0.48)_regulation_of_macromolecule metabolic_process GO:0010604_(0.46)_positive_regulation_of macromolecule_metabolic_process GO:0035556_(0.43)_intracellular_signal transduction GO:0010468_(0.43)_regulation_of_gene_expression GO:0048017_(0.41)_inositol_lipid-mediated signaling GO:1901576_(0.34)_organic_substance_biosynthetic process GO:0044249_(0.34)_cellular_biosynthetic_process GO:0032502_(0.34)_developmental_process GO:0044767_(0.33)_single-organism_developmental process GO:0006796_(0.33)_phosphate-containing_compound metabolic_process GO:0044710_(0.32)_single-organism_metabolic process GO:0016310_(0.32)_phosphorylation GO:0046834_(0.31)_lipid_phosphorylation CC: GO:0016020_(1.00)_membrane GO:0043234_(0.90)_protein_complex GO:0005942_(0.85)_phosphatidylinositol_3-kinase complex GO:0005737_(0.74)_cytoplasm GO:0005886_(0.69)_plasma_membrane GO:0005829_(0.60)_cytosol GO:0044430_(0.47)_cytoskeletal_part GO:0044421_(0.35)_extracellular_region_part GO:0005773_(0.34)_vacuole GO:0044428_(0.33)_nuclear_part GO:0043232_(0.32)_intracellular_non-membrane- bounded_organelle GO:0042995_(0.32)_cell_projection GO:0031982_(0.32)_vesicle GO:0031988_(0.31)_membrane-bounded_vesicle | UniProt annotation: GO:0005515_protein_binding UniProt annotation score: ◉◉◉◉◉ NextProt annotation: GO:0005515_protein_binding | High: | |
66 | >NX_Q9BQA9-1|CQ062_HUMAN Uncharacterized protein C17orf62 GN=C17orf62 MYLQVETRTSSRLHLKRAPGIRSWSLLVGILSIGLAAAYYSGDSLGWKLF YVTGCLFVAVQNLEDWEEAIFDKSTGKVVLKTFSLYKKLLTLFRAGHDQV VVLLHDVRDVSVEEEKVRYFGKGYMVVLRLATGFSHPLTQSAVMGHRSDV EAIAKLITSFLELHCLESPTELSQSSDSEAGDPASQS chromosome location: 82442589-82450829 (17q25.3) Database cross references: | MF: GO:0035639_(0.57)_purine_ribonucleoside triphosphate_binding GO:0032559_(0.57)_adenyl_ribonucleotide_binding GO:0032550_(0.57)_purine_ribonucleoside_binding GO:0051427_(0.37)_hormone_receptor_binding GO:0031701_(0.37)_angiotensin_receptor_binding GO:0005126_(0.37)_cytokine_receptor_binding GO:0004672_(0.37)_protein_kinase_activity BP: GO:0044351_(0.83)_macropinocytosis GO:0048870_(0.32)_cell_motility GO:0048869_(0.32)_cellular_developmental_process GO:0046777_(0.32)_protein_autophosphorylation GO:0018108_(0.32)_peptidyl-tyrosine phosphorylation GO:0008283_(0.32)_cell_proliferation GO:0007165_(0.32)_signal_transduction GO:0006955_(0.32)_immune_response GO:0006952_(0.32)_defense_response CC: GO:0043232_(0.79)_intracellular_non-membrane- bounded_organelle GO:0044430_(0.74)_cytoskeletal_part GO:0005856_(0.74)_cytoskeleton GO:0005737_(0.74)_cytoplasm GO:0005874_(0.68)_microtubule GO:0005829_(0.68)_cytosol GO:0005871_(0.63)_kinesin_complex GO:0016020_(0.53)_membrane GO:0005634_(0.53)_nucleus GO:0005815_(0.42)_microtubule_organizing_center GO:0005819_(0.37)_spindle GO:0005876_(0.32)_spindle_microtubule | UniProt annotation: GO:0005515_protein_binding GO:0016020_membrane GO:0016021_integral_component_of_membrane UniProt annotation score: ◉◉○○○ NextProt annotation: GO:0005515_protein_binding |