CEthreader results for example

[Click result.zip to download all results on this page]

Input Sequence in FASTA format

>example (69 residues)
AGCNAGQLTVCTGAIAGGARPTAACCSSLRAQQGCFCQFAKDPRYGRYVNSPNARKAVSS
CGIALPTCH

Predicted Secondary Structure

Sequence	20 40 60 \| \| \| AGCNAGQLTVCTGAIAGGARPTAACCSSLRAQQGCFCQFAKDPRYGRYVNSPNARKAVSSCGIALPTCH
Prediction	CCCCHHHCSSCHHHHHCCCCCCHHHHHHHHHHCCCCCCSSCCCCHHHHCCCHHHHHHHHHCCCCCCCCC
Conf.Score	998855564449999879999999999999877985545359557987899999999998799999899
	H:Helix; S:Strand; C:Coil

Contact Prediction used to guide CEthreader

Download contact map.

Top 20 Templates Identified by CEthreader

Rank

PDB
Hit

ID1

ID2

Cov

Norm.
Zscore

Download
Alignment

                  20                  40                  60

                   |                   |                   |

Sec.Str.
Seq

CCCCHHHCSSCHHHHHCCCCCCHHHHHHHHHHCCCCCCSSCCCCHHHHCCCHHHHHHHHHCCCCCCCCC
AGCNAGQLTVCTGAIAGGARPTAACCSSLRAQQGCFCQFAKDPRYGRYVNSPNARKAVSSCGIALPTCH

1gh1A

0.26

0.25

0.96

1.52

CEthreader_1

CGHVDSLVRPCLSYVQGGPGPSGQCCDGVKNLHNCLKGIARG---IHNLNEDNARSIPPKCGVNLPYTI

1tukA

0.60

0.58

0.97

1.52

CEthreader_2

-ACQASQLAVCASAILSGAKPSGECCGNLRAQQGCFCQYAKDPTYGQYIRSPHARDTLTSCGLAVPHC-

5tviV

0.25

1.00

1.45

CEthreader_3

CGQVDANLAPCVPFLTQGGEPGAACCSGVKTLNGNAQSIKAAANRYPNLKDDAAQSLPSKCGISLNVPI

1bv2A

0.30

1.00

1.45

CEthreader_4

ITCVNSAVGPCLTYARGGAGPSAACCSGVRSLKATACNLKNAARGIKGLNAGNAASIPSKCGVSVPYTI

4xuwA

0.25

0.99

1.43

CEthreader_5

LTCPKGNLTPCVLYLKNGGVLPPSCCKGVRAVNDCNCLKDTAKGIAG-LNPNLAAGLPGKCGVNIPYKI

2rknA

0.25

1.00

1.39

CEthreader_6

CGMSQDELNECKPAVSKPTSPSQPCCTALQHAFACLCGYKNSPWLGSFVDPELASALPKQCGLANAPTC

2n2zA

0.22

0.99

1.27

CEthreader_7

LTCGTGALAPCLGYLRTSVPVPLTCCNGVRGLNNCNCLKQTANAIAD-LNLNAAAGLPAKCGVNIPYKI

1siyA

0.25

0.99

1.21

CEthreader_8

CGQVQGNLAQCIGFLQKGGVVPPSCCTGVKNILNCSCLKAAAGAVRG-INPNNAEALPGKCGVNIPYKI

2ljoA

0.24

0.23

0.99

1.18

CEthreader_9

CGAVTSDLSPCLTYLTGGPGPSPQCCGGVKKLLACNCLKSAAGSITK-LNTNNAAALPGKCGVNIPYKI

1t12A

0.21

0.20

0.97

1.09

CEthreader_10

CGQVTSNLAPCLAYLRNTGP-LGRCCGGVKALVNCTCLKSAAGAISG-INLGKAAGLPSTCGVNIPYKI

5domA

0.17

1.00

1.02

CEthreader_11

QFQTQQRLRACQRVIRRWSPTLQRCCRQLRNSPFCRCPSLRQAVQSAQQMYRVASRIPAICNLQPMRCP

1l6hA

1.00

1.02

CEthreader_12

AGCNAGQLTVCTGAIAGGARPTAACCSSLRAQQGCFCQFAKDPRYGRYVNSPNARKAVSSCGIALPTCH

1pavA

0.06

0.91

0.93

CEthreader_13

DVKPDRVIDARGSYCPGPLMELIKAYKQAKVGEVISVYSTDA------GTKKDAPAWIQKSGQELVGVF

3lxzA2

0.07

1.00

0.93

CEthreader_14

ELYIELPARTCYAESFFGSVEKEKARADLLAGFATLKRNGRQLTLADLFSVDLANAVGKKVLNIDFLAD

5o84A

0.09

1.00

0.88

CEthreader_15

ADYIDKKTYVPKALWSESGEKQEAAKIEFIEVLKTLDSELGDKYYFGGNEYSWFRTYEEVANLSIVLEF

1psyA

0.21

0.20

0.99

0.88

CEthreader_16

QEVQRKDLSSCERYLRQESQQLQQCCNQVKQVRDCQCEAIKHGEESERVA-QRAGEIVSSCGVRCMRQT

3au2A

0.04

1.00

0.84

CEthreader_17

QKAKEKGVAVEIDGYYDRMDLPDDLARMAYGMGLWISLSTDAHQTDHLRFMELAVGTAQRAWIGPERVL

3ab7A2

0.12

1.00

0.84

CEthreader_18

APGEPVELEGALLGYDASESALHALAPLARALLGVRVVSVHEDPARAEAWALEAEAYLRDHGVEASALV

2pd6D1

0.18

0.14

0.83

0.84

CEthreader_19

-NRLRSALALVTGAGSGIGR--AVSVRLAGEGATVAACDL---------DRAAAQETVRLLNHAAFQAD

3au2A3

0.04

1.00

0.84

CEthreader_20

QKAKEKGVAVEIDGYYDRMDLPDDLARMAYGMGLWISLSTDAHQTDHLRFMELAVGTAQRAWIGPERVL

(a)	ID1 is the number of template residues identical to query divided by number of aligned residues.
(b)	ID2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A normalized Z-score ≥1 means a good alignment.
(e)	Sec.Str. is predicted secondary structure, with H, S and C representing helix, strand, and coil, respectively.

Top Final Models

CEthreader uses MODELLER to reconstruct full length models from top 5 templates. By dragging your mouse on the images, you rotate and zoom the structure.

Download Model 1

Download Model 2

Download Model 3

Download Model 4

Download Model 5

[Click result.zip to download all results on this page]

References:
1.	W Zheng, Q Wuyun, Y Li, SM Mortuza, C Zhang, J Ruan and Y Zhang. Detecting distant-homology protein structures using contact-map guided threading. Submitted.