>PF12449 (1087 residues) LTFVALQHIEFWIDDWKILDLHKKTSPSLEVPIPRDIETRTREGLMKVNSVERASTQIDA AIMSAAGWKPKAVTTSKTTDQYGLGSEVPSLRSFFSRLTSTATQATAKKQQREEAAAQEE IGEDVTKVSTSTIFLRVTTASVQTSVSTSFATELERATKKPPPKTTKLAILTSSYDETMA SESSRSATISKSVDVFASVLPSKKPGGRIFIGFPTTQTTGAGMHISAQSVIPTVEREAID LNARWVRTWNIEMLRAAGIMTRLAFINEMSDLDAKVKKLVGAGTKIGPEDMAKLLPEALH VFKTFSFTDSTPSGQVSQILEEAFWTAYKRASVEVFSSRGVLPTTKVRIGSEELAKFVDT IPVVPRELIENAFVRKLMDFGLISHITVDDVRTELESKAMNKEQLINFITWAGRKALSGE LDPPSKARLLDVAVATVSEDGSDQGDIIALGTITNYQVANKIPANLPIPPTTIPLAYTNT CTAAELQALGWDPLEVVPWLRFLIEYNANRPDEQNLKKSPKFAVQILTVLSKNWENTSQS SKATIITLLQAHTVMPTKMGMKRPTDSFFPSVKLFDDLPIIQGCQSLKEKFLSAIGVRKT VDLDTIFSRLLSPSAEGGKQRWSHMELIKYLASVKDDIPADDMKKLKETRFCPAEAGEKG MEPTKGTTALHKVSELFEPKDTLRSLRLPILQWPGPPGSYRSNSNEGKFLTKLGLRPYPS VSEMVDLMSSGDADLRVSAMTYFVANHQINGYGSYSLSDSRKAFLPLQNDNKLVAPSSCF TNESAAVLGFDILRKDLHLHANKFGVVRDPPIAECVARLLARPPRDRQMAVTLFEYFAMR LADLGEGSLAKLRDATIVPVTRQTREGNNNSTGEKPVPKVTLVSPRQCYLGSSATYGNIF DFVDFGANANTFLYKCGAKSEPTKPEIAHLACNEPARLLNTLQSPDKYLALLKSLAENMA TLKRDRELFKKMKTSPFLLAAKEIASPPSKDKLIDVDDDEAPIKQYQLATASRIVILDDI ISYRLFKDYLITAPEEEVLEDFYHQLGAQTLSSLVEEEVRIGPHADKQDRAAALRKHVLE RSKIFLH |
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Rank | PDB hit | ID1 | ID2 | Cov | Norm. Zscore | Threadingprogram | 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 1000 1020 1040 1060 1080 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Seq | LTFVALQHIEFWIDDWKILDLHKKTSPSLEVPIPRDIETRTREGLMKVNSVERASTQIDAAIMSAAGWKPKAVTTSKTTDQYGLGSEVPSLRSFFSRLTSTATQATAKKQQREEAAAQEEIGEDVTKVSTSTIFLRVTTASVQTSVSTSFATELERATKKPPPKTTKLAILTSSYDETMASESSRSATISKSVDVFASVLPSKKPGGRIFIGFPTTQTTGAGMHISAQSVIPTVEREAIDLNARWVRTWNIEMLRAAGIMTRLAFINEMSDLDAKVKKLVGAGTKIGPEDMAKLLPEALHVFKTFSFTDSTPSGQVSQILEEAFWTAYKRASVEVFSSRGVLPTTKVRIGSEELAKFVDTIPVVPRELIENAFVRKLMDFGLISHITVDDVRTELESKAMNKEQLINFITWAGRKALSGELDPPSKARLLDVAVATVSEDGSDQGDIIALGTITNYQVANKIPANLPIPPTTIPLAYTNTCTAAELQALGWDPLEVVPWLRFLIEYNANRPDEQNLKKSPKFAVQILTVLSKNWENTSQSSKATIITLLQAHTVMPTKMGMKRPTDSFFPSVKLFDDLPIIQGCQSLKEKFLSAIGVRKTVDLDTIFSRLLSPSAEGGKQRWSHMELIKYLASVKDDIPADDMKKLKETRFCPAEAGEKGMEPTKGTTALHKVSELFEPKDTLRSLRLPILQWPGPPGSYRSNSNEGKFLTKLGLRPYPSVSEMVDLMSSGDADLRVSAMTYFVANHQINGYGSYSLSDSRKAFLPLQNDNKLVAPSSCFTNESAAVLGFDILRKDLHLHANKFGVVRDPPIAECVARLLARPPRDRQMAVTLFEYFAMRLADLGEGSLAKLRDATIVPVTRQTREGNNNSTGEKPVPKVTLVSPRQCYLGSSATYGNIFDFVDFGANANTFLYKCGAKSEPTKPEIAHLACNEPARLLNTLQSPDKYLALLKSLAENMATLKRDRELFKKMKTSPFLLAAKEIASPPSKDKLIDVDDDEAPIKQYQLATASRIVILDDIISYRLFKDYLITAPEEEVLEDFYHQLGAQTLSSLVEEEVRIGPHADKQDRAAALRKHVLERSKIFLH | |||||||||||||||||||
1 | 1u6gC | 0.12 | 0.09 | 3.28 | 1.20 | SPARKS-K | SAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCFVDLIEHLLSELSKNDSMSTTRTYIQCIAAISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYESFVRRC----PKEVYPHVSTIINICLKYLTYDM--------SWKVRRAAAKCLDAVVSTRHEMLPEFYKT---------------------------VSPALISRFKEREE----NVKADVFHAYLSLLKQTPLTMLQSQPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVL----PGALTQHIPVLVPGIIFSLNDKSLYVILCN---------HSPQVFHPHVQALVPPVVACVGDLVTQQLVKVIRPFDATFTCTIKRLKAADIDQEVKERAISCMGQIICLGSDLPNTLQIFLERL-------KNEITRLTTVKALTLIA---GSPLKIDL------RPVLGEGVPILASFLRKNQLGTLSALDILIKNYSDSLTAAMIDAVMHVSQMAISFLTTLLSKISGSILNELIGLVR------------------SPLLQ--------GGALSAMLDFFQALVVTGTLGYMDLLRMLTGPVYSQTHKQSYIAKCVAALTRACPKEGP----AVVGQ-FIQDVKNSR-------------------STDSIRLLALLSLGEVGHHIDLSGQLELKSVILEAFSSPSGNLPEYLPFVLQEQPKRQYLLLHSLKEIISSASVVGLKVENIWALLLKHCECAE----------EGTRNVVAECLGKLTLI-----------DPETLLPRLKGYLIGSSYARSSVVTAVKFTISDHPQPIDPLLKNCIG-----------------------------------------------------DFLKTLEDPDL----NVRRVALVTFNSAAHNKPSRDLLDTVLPHLYNETKVRKEVDDGLDIRKAAECMYTLLDSCL------------DRLDIFEFHVEDG----LKDHYDIKMLTFLMLLSTLCPSAVLQRLDRL-VEPLRATCTT--KVKANSVKQEKQDELKRSAMRAVAALLT | |||||||||||||
2 | 5ijnD | 0.12 | 0.09 | 3.32 | 1.70 | FFAS-3D | --------------------------------------------------------------------------------------SAASLWGPYKDIWHKVGLLDKILKKHKPDFISLFKNPPKNVQQHEKV----QKASTERLLPEQLIKEAFILSDL------------FDIGELAAVELLLAGEHQQLVAVLL--------------------------YWDGKRCIANSLKALIQSRRPELASMTTRFTGLTYKVLTLVSQIDVNNEFEKLQRERGLGSEKHRKEVSDLIKE------------------CRQSLAESLFAWACQSP---------LGKEDT----LLLIGHLERVSLDAVNLALLALLYCFDISFIEQKQYIATIHSRLQLWKLPGLQATVRLAWALALRGISQDEAMAELAIADNVFLFLMESVVVSQEEFYIRRVHNLITD---------FLALMPMKVKQLRNRADLEHLKNPELALEYWSKFVRQMGDLLPPTQGLANGPQCAHYCFSLLKVSWEHFLQKEQDGLIAFLQLTSTIITWSENARLALCETPVVVILGLLQCSIPLKAELLKTLAAF-GKSPEIAASLWQSLEYTILQTVRIPSGIEVELNEIESRCEEYPLQLISTLVESSF-PSNLGAGLRPPGFDPYLQFLRDSVRARAAEKWEVAEVVLEVDFGEEIIAYKPPGFSLMYHL--LNEPMLELALSLLEEGVKKHLEKAVQHCLALLNL---TLQKENLFMDLLRESQLVCPLEQLLQGINPKADNVVNIARYNPELAFESAKIDSSLYIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQDTLEAAKKTM--------------WERLTAPEDVFSKLQREN---------------IAIIESYGAALMEVVCRDACDGHEIGRMLALALLDRIVSVDKQQQWLLYLSNSGYLKVLVDSLVEDDRTLQSL--------------------LTPQPPLLKALYTYESKMAFLTIQQGALELLRSGVIMRPEPTPVDRYRQILLALQLCQVI----LTSSMAQHLQAAGQVLQFLISHSDTI-- | |||||||||||||
3 | 2pffB | 0.16 | 0.07 | 2.26 | 0.78 | HHpred | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAYSTRPLTLSEHVLLVPTASFFIASQL-----------QEQFNKILPEPT-EGFADDEPTTPAELVGLGYVSSLVEPSKVGQFVLNLCLTEFENCYLEGNDIHALAAKLLQENDTTVKTKELIKNYITARIMAKRP------FDKKSNSALFRAVGEGDDYDLYQTYHVLVGDLI-KFSAETLSTLVFQGLNILEWLENPSN-----TPDKDYLLSIPISCPLIGVIQLAHYKLLGFTPGELRSYLKGATGHSQGLVRKAITVLFFIGVRCYEAYPNTSLPPSILEDSLEN---NEGVP-----SPMLSIS------NLTQEQVQDYVNKTN--------------SHLPAGKQVEISLGAKNLVVSGPPQSLYGLNLTLRKAKIPFSERKL---KFSN-----RFLPV----ASPFHSHLLVPAS--DLINK-----DLVKNNV-----SFNAKDIQI---PVYDT---------F---D----------------GSDLRVLSGSISERIVDCIIRLPVKWETTTQ----FKATHILDFGPGHRNKDGTGVRVIVAGTLDI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | |||||||||||||
4 | 1u6gC | 0.13 | 0.12 | 4.15 | 1.28 | MUSTER | FRFMATNDL--------MTELQ-KDSIKLDDDSERKV-----KMILKLLEDKNGEVQNLAKCLGPLVSKVKEYTNMLSDKEQLRDISSIGLKTVIGEL-PSALAANVCKKITGRLTSAIAKQEDVSVQLEA---LDIM-ADMLSRQGGLLVNFHPSILT--------LPQLTSPRLRKRTIIALGHLVMSCFVDLIEHLLNDSMSTTRTYI-----QCIAAISRQAGHRIGEYLE-KIIPLVVKFCNELREYCIQAFESFVRRCPKEVYPHVSTIINICL---KYLTYDMSWKVRRAAAKCLDAVV--STRH-EMLPEFYKTVSPALISR-----FKE----REENVKAD-HAYLSLLKQTRP-------ETPLTMLQSQ--VPNI-VKALHKQMKEKSVTRQCCFNMLTELVNVL--PGALTQHIPVLVPGIIFSLNDKSSSSNKIDALSCLYVIL--CNHSPQVFHPQALVPVACVGDPFYKITSEA----LLVTQQLVKVIRPL-DQPSSFDA---TPYIKDLFTCTIKRLKAIDQEVKERAISCMGQ--II-CNLGDNLGSDL----PNTLQIFLERLKNEITRLTTVKALTAGSPIDLRPVLGEGVPIRKNQRALKLGTLSALDILIKNSDSLTAAMIDAVLD-ELPPLISESDMHVSQMAISFLTTLAKVYISGSILNEL-IGLVRSPLLQGGALS--AMLDFFQALVGTNNLGYMDLLRMLTGPVYKQSYYSIAKCVAALTRACPKEG--PAVVGQFIQDVKNSR--------STDSIRLL---AL-LSLGEVGHHIDLSGQLELKSVILEAFSSPEEVKSAASYALGSISVGLPEYLPFVLQEITSQPIISSASVVGLKPYLKHCECAEEGTRNVVGKLTLIDPETLLPRLKGYLISGSYARSSVVTA-ISDHPQ--PIDPLLKNCIGDFLKTLEDRRVALVTFNSAAHNKPSLIRDPHLYNETKVRKEL--IREVEMGPFKHTVDDSCLDRLDIFEFHVEDG----LKDHMLTFLMLVR--LSTLCPSAVLQRLDRL-VEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLT | |||||||||||||
5 | 3m1iC | 0.10 | 0.06 | 2.20 | 1.72 | CNFpred | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADQILQFSPQSKFIALSILDKLITRKWKLL-------PNDHRIGIRNFVVGMIISMCQDDEKTQKNLINKSDLTLVQIL-----KQEWPQN------WPEFIPELIGSSSSSVCENNMIVLKLLSEEVFDFEQMTQAKALHLKNSMSKE---FEQIFKLCFQVLEQGS----SSSLIVATLE--------------------SLLRYLH--WIPYRYIYETNILELLSTKFMTSPDTRAI------TLKCLTEVSNLK-------IPQDNDLIKRQTVLFFQNTLQQIAMPVTADLKATYANA-----GNDQSFLQDLAMFLTTYLARNRALLELRELLLNAHQYLIQLSKIEERELFKTTLD----------YWHNLVADLFYEKKHIYEEICSQLRLVI----------------------IENMVRPE------EVLVVEND--GEIVR-ESDTIQLYKS--------EREVLVYLTHL---NVIDTEEIMISKLARQIGSEWSWHNINTLSWAIGS------ISGTMSEDTEKR----FVVTVIKDLLDLTVKKRGKDNKAVVASDI------MYVVGQYPRFLKAHWNF-LRTVILKLF--EFMHET------------------HEGVQDMACD-----------TFIKIVQKCKYHFVIQQ----RESEPFIQTIIRDIQKTTADLQQVHTFYKACGIIISEERSVAERNRLLSDLM-QLPNMAWDTIVEQSTANPTLLLD----SETVKIIANIIKTNVAVCTSMGADFYPQLGH--IYYNMLQLYRAV-SSMISAQVAAEGLIATKTPKVRGLRTIKKEILKLVETYIS | |||||||||||||
6 | 2pffB | 0.13 | 0.06 | 2.01 | 1.38 | HHsearch-2 | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAYSTRPLGSLEHVLLVPTASFFIASQQNKILPEPTEGFAA---------------DDEPTTPAELVGLGYVSSLVEPSKVGQFVLNLCLTEFENCYLEGNDIHALAAKLLQENDTTVKTKELIKNYITARI---MA-----KRPKKSNSALFRAVGEGNAQLVAIQGNTDDYFLSELIRTTDAEVF-TQGLNILEWLENPSNT-----PDKDYLLSIPISCPLIGVIQLAHY--------VVTAKLL---------G-FTPGRSYLKGATGHS------------QG------------LVTA-VAIAET------DSWE-----SFFVSVRKAITVLFFIGVRCYEAYPNTSL---------------PPSILEDSLENNEGPSPMLSIS----------------------NLT-------------QEQVQDYVNKT------------------NSHLPAGKQISLVNGANVVSGPPQSLYGL-------NLTLRKA-----------------KAPSGLDQSRIP---FSERKLKF---------SNRFLPVASPFH-------------SHLLVPASDLINKDLVKNNKDIQIPVYDTFDG---SDLRVLS----------------------GSSERIVDCIIRLPVKWET-------TTQFKATHI----------------------------------------------------LDFGPGGA------SGLGVLTHRNKDGVRVIVAGTLDI--------------NPDDDY | |||||||||||||
7 | 1u6gC | 0.10 | 0.09 | 3.30 | 2.18 | Neff-PPAS | ----------------------------------------------------------------------------EKMTSSDKDFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDKNGEVQNLAVCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCFVDLIEHLLSELSKNDSMSTKFCNVDDDELREYCIQAFESFVRCPKEVYPHVSTIINICLKYLTYDMS-----------WKVRRAAAKCLDAVVSTRHEMLPEFYKTVSPALISRFKQVPNI-VKALHKQMKEKSVKRQCCFNMLTELVNVLPGA--LTQHIPVLVPGIIFSLNDKSSSNLKIDALSCLYVILCNHSPQVFHPHVQALV-PPVVACVGDPFYKITSEALLVTQQLVKVIRPLDQPSSFD-----ATPYIKDLFTCTIKRLKAIDQEVKERAISCMGQIICNLGDNLGSDLPNTLQIFLERLKN----EITRLTTVKALTLIAGSPLIDLRPVLGEGVPILASFLRKNGTLSALDILIKNYSDSLTAAMIDAVLDELPPLIS--------ESDMHVSQMAISFLVYPSSLSKISGSILNPLLQGGALSAMLDFFQALVVTGTNN-LGYMDLLRMLTGPHKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDVKNSRSTDSIRLLALLSLGEVGHHIDLSGQLELKSVILEAFSSPSENLPEYLPFVLQEITSQPKRQYLLLHSLKEIISSASVVGLKPYVENIWALLLK---------HCECAEEGTRNVVGKLTLIDPETLLPRLKGYLGSSYARSSVVTAVKFTISDHPQPIDPLLKNCIGDFLKTLEDRRVALVTFNSAAHNKPSLIRDPHLYNETKVR------KELIREVEMGPFKHTVDDGLDIRKAAFECMYTLLSCLDRLDIFEFLNHVEDGDHYDIKMLTFLMLVVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLT | |||||||||||||
8 | 2pffB | 0.11 | 0.06 | 2.04 | 2.08 | HHsearch | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MD-AYSTRPLTLSH-GSLEHVLLVPTASFFIASQFNKILPEPTEGFAADDEPTTPAELVGKFLGSSLVEPSKVGQQVLNLCLTEFE---------------NCYLEGNDIHALAAKLLQENDTLVKTKELIKNYITARI---MA-----KRPKKSNSALFRAVGEGIFNTDDYELQTYHVLVGDLFSAETLSVF-TQGLNILEWLENPSNT-----PDKDYLLSIPISCPLIGVIQLAHY--------VVTAKLL---------GF-TPGRSYLKGATGHSQ------------GLVTA-------------VAIAET------DSW-----ESFFVSVRKAITVLFFIGVRCYEAYPNTSL---------------PPSILEDSLENNEVPSPMLSISN-----LTQEQVQDYVNHLPA-GKQVEISLVNGAKNGPPQSLYGLNLTLRKAKAPSGLDPFSERKLKNRFLPVASPHLLVPASDLINKDKNNSFNAKDIQIVYDFDGSDLRVLSGSISERIVDCIIRLPVKWETT----TQFKATHILDFGPGHRNKDGTGVRVIVAGTLD-----------------INPD---------DDYGFKQGGGGGGGGG----GGGGGGGGGG-----------------GGGGGGGG------GGGGGGGGG---------------------------GGGGGGGGGGGGGGGGGGGGG-------GGGGG-GGGGGGGGGGGGGGG---GGGGGG-GG-----GGGGGGGGGGGGG---------------- | |||||||||||||
9 | 5b2oA | 0.08 | 0.07 | 2.61 | 1.69 | PROSPECTOR2 | MNFKILP-IAIDLGVKNTGVFS--------AFYQKGTSLERLDN--------KNGKVYE---------------------LSKDSYTLLMNNRTARRHQRRGIDRKQLVKRLFKLIWTEQLNLE---------------------WDKDTQQAISFLFNRRGFSFIT-----DGYSVKAILMDIFDDYNGEDDSYLKLATEQ-------------------------------------------ESKISEIYNKLMQKILEFKLMKLCTDIKD------DTLKEITSYEFELLADYLANYSESLKTQKFYNIQEFLKRHATINDRILDT------------------LLTDDLDIWNFNFELHHFVFAVNKIKSEMASGGRHRSQYFQEITNVLDENNHQEGYLKNFCENLHNKKYSNLSVKNLVNLIGNLSNLE-------------LKPLRKYFNDKIHAKADHWDEQKFTETYCHRVGVKDQDKKDGAKYSYKDLCNELKQKVTKAGLVDFLLENPKFLDNQWQQYLQELKKLQSIQNYLFETDLKVLK------SSKDQPYFVEYKSSNQQIASGQRDYKDLDARIL-----------QFIFDR------VKASDELLLNEIYFQAKKLKQESSKKLDEVIANSQLSQILKSQHTNGIFEQGTFLHLVCKYYKQRQRARDSRLYIMPEYRYDKKLHKYNNTGRFDDDNQLNHKPRLLNDLAGVLQVSPNFLKDKIDLFISKWLVEHIRGF---------------------------------------KKACEDSLKIQKDNRGLLNHKINIARNTKGKCEKEIFNLICKIEGYKHGLAYELGVLLFGEP-------------------NEASKPEFDRKIKKFNSIYSFAQIQQIAFAEAVCSADNAHRMQQIKIIAKNIVDDNWQNIKQVLSAKHNAFEFEPALADVLERISPENIFKDKNNRIKEFAEELDLICVTGNRIFCLRDNYRSFINLTPQEQKAFRHALFLADENPIKQAVIRAINNRNREVLANNIYLRAKENLNTDKISFDYFGIPTIGNGRGIAEIRQLYEKVDSDIDK | |||||||||||||
10 | 2c1gA | 0.17 | 0.03 | 0.85 | 0.19 | SAM | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FDDGPNPAKYDIKATFFVLGKNVSGNED---LVKRIKSEGHVVGNHSWSHPILSQLSLDAKKQIT-------DTEDVLTKVLG--------SSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDWKSKNEASILTEIQHQ-VANGSIVLMHDIH----SPTVNALPRVIEYLKNQGYTFVTIPEM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | |||||||||||||
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References: | |
1. | Wei Zheng, Yang Li, Chengxin Zhang, Robin Pearce, S. M. Mortuza, Yang Zhang. "Deep-learning contact-map guided protein structure prediction in CASP13." Proteins: Structure, Function, and Bioinformatics, 87: 1149-1164 (2019). |