>PF04632 (615 residues) QQPQWALMTAFIVAQPLSGMVVQKGLARLLGTLVGTFMAVVMMGLFAQAPLLFVLAFALW LALCTASSTMLRSAWSYSFVLAGYTVAIIALPAIGKPHVVFDEAIARCTEICLGITCATL SSALLWPQRVERQLAQQARNAWQAGVAASRQALAGEADSRQGLLEVLARIVAVDAQREHA WFEGAQGRQRAVALRVLSRDLLGMLRLARGVARQWRQLSSSEAQAVAPWLQVVDERLQQV QPAGLLELVEQLRQAAQDEELSSGQQLCLERLMVLLLRVEDASRALFSVEEGRAPADAPR ALSWHYDWQTALVYGSRSALTFLVLAAFWLATGWTHATGALLLACVVCSLFARLEAAPQI GMMFLRGIFYALPVAFFVGQILMPQIDGFVMLCMVLGVPLFFGVLGMAKPATAATSTSFC LHFIVLCLPAPGVGYNVEFFLNEAPGMLIGVGCAVMAFKLVVLRNPVWHGRRLMQAILTD LGRLTRRDLGRAENWFGGRMADRLLQLARHYPARPDQARSRWDDGVAGLDLGDELLHLRK CLANADAGLARSQQRFLEHLDDALERGPAPGREDDLNAAVAELQEALRACTPSIDKRLAE AALLQLQSGWRHWCH |
|
Rank | PDB hit | ID1 | ID2 | Cov | Norm. Zscore | Threadingprogram | 20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Seq | QQPQWALMTAFIVAQPLSGMVVQKGLARLLGTLVGTFMAVVMMGLFAQAPLLFVLAFALWLALCTASSTMLRSAWSYSFVLAGYTVAIIALPAIGKPHVVFDEAIARCTEICLGITCATLSSALLWPQRVERQLAQQARNAWQAGVAASRQALAGEADSRQGLLEVLARIVAVDAQREHAWFEGAQGRQRAVALRVLSRDLLGMLRLARGVARQWRQLSSSEAQAVAPWLQVVDERLQQVQPAGLLELVEQLRQAAQDEELSSGQQLCLERLMVLLLRVEDASRALFSVEEGRAPADAPRALSWHYDWQTALVYGSRSALTFLVLAAFWLATGWTHATGALLLACVVCSLFARLEAAPQIGMMFLRGIFYALPVAFFVGQILMPQIDGFVMLCMVLGVPLFFGVLGMAKPATAATSTSFCLHFIVLCLPAPGVGYNVEFFLNEAPGMLIGVGCAVMAFKLVVLRNPVWHGRRLMQAILTDLGRLTRRDLGRAENWFGGRMADRLLQLARHYPARPDQARSRWDDGVAGLDLGDELLHLRKCLANADAGLARSQQRFLEHLDDALERGPAPGREDDLNAAVAELQEALRACTPSIDKRLAEAALLQLQSGWRHWCH | |||||||||||||||||||
1 | 4xriA | 0.10 | 0.10 | 3.61 | 1.23 | SPARKS-K | LSPDATLRHAAEQQLTHAAETNFSQYLLTLVQALAGHIRAAAGIALKNAALQAKWLNTRTRVKQLALETLASPNSKAGQAAAQVIAAIAAIELPRQWPELMHALVRNASEQHQKQASLTAIGFICETQD--TDLRNSLVGHSNAILTAVVQGARKEEPNNEVRFAAITALGDSLEFVGNNFKHEGERNYIMQVVCEATGAFGCLNRIMALYYEHMRYYMEKLFGLTILGMEDVAKLAVEFWSTVCEEEIAIEDDNAQVEQMRPFYNFARVATNEVVPVLLQLLT--------KQDEDASDDEYNISRAAYQCLQLYAQAVGSTIIPPVIQFVEWHFRDAAVSAFGAIMVLEPIVKTGMQPLIAMMEVRDSTAYALGRITEACSEAID----PNTHLEPLIRSLFNGLMNSPKMAASCCWALMNIAERFAAAQNPLTFNQSVTNLLTVTVRTAAYEVLSVFVAANDSLSAVASLSTVILQRLEETLPLEDKLILEDMQTSLCTVLQATVQRLDKEIAPQGDRIMQVLLQILPEGVFAAISALANAMEEEFAKYMEAFAPFLYNALGNQEEPSLCSMAIGLVSDVTRSLGERSTTLANQFKPAILQCFGDIASAIGG | |||||||||||||
2 | 4iggA | 0.11 | 0.10 | 3.66 | 1.91 | FFAS-3D | ESQFLAVEDVRFADDPCS-SVKRGNMVRAARALLSAVTRLLIL--ADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLNELKDVGHRDQMAAARILQKNVPILYTASQACLQHPVAAYKANRDLIYKQLQQAVTGISNAAQATASDDGGGGELAYALNNFDKQIIVDPLSFSE-ERFRPSLEERLESIISGAALMADRRERIVAECNAVRQALQDLLSEYMGNARKERSDALNSAIDKMTKKTRD-LRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGN--------------EKEVKEYAQVF---------------REHANKLIEVANLACSISNNEEGVKLVRMSASQLLCPQVINAALALAAKPQSKLAQENMDLFKEQWLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAVIHVVTSEMDNYEPGVYTEKVLEATVEAAVEALSSDPAQEFIDASRLVYDGIRDIRAIMAQLPQEQKAKIAEQVASFQEEKS--KLDAEVSKWDDVLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRCPDSACKQDLLAYLQRIALYCHQL-- | |||||||||||||
3 | 4mt1A | 0.11 | 0.08 | 2.84 | 0.33 | HHpred | ----EAMVLVFVVMYLFLQN-IRYTLIPTIVVPISLLGGFAFISYMGMSIVLTMFAMILVIGIVVVVENVERGPISGAVIGITAVLISVFVPLAMFSGAAGNIYKQFALTMASSIAFSAFLALTLTPALCATGFFGSWTHGYEGRVAKV-------------------------------------LRKTF--R-MMVVYIGLAVVGVFLFMRLPTSLPAATKERTDATLAQVTQLAKSIPVAVAGKLTGMMGTLKDGPNTGHTLLAKRNELIQKMRASGDIRTALASALSSVATERPSASPATGVST-GQAMEAVQKMVD-----------ELGGGYSFEWGG-QSSEEAKG-------GSQTLILYGLAVAAVFLVLAAL---YESWSIPLAVIIPLGLIGAA---------AGVTGRNLFEGLLGSVPSFANDIYFQV--GFVTVMGLSAKNAILIIE-------FAKDLQASAVEAALEAARLR---FRPIIMTSFAFILGVVPLYIAAG-A-SSASQRAIGTTVFWGMLVGTLLSVF------------------------------------------------------------------------- | |||||||||||||
4 | 1b3uA | 0.12 | 0.11 | 3.76 | 1.16 | MUSTER | DDSLYPIAVLIDELR----VQLRLNSIKKLSTIALALGVERTRSELL--PFLTDTIDEVLLALAEQLGTFT-TLVGGPEYVHCLLPPLESLATVEE------TVVRDKAVESLRAISHEH-----SPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLQDSVRLLAVEACVNIAQLL--PQEDLEALVMPTLRQAAED-KSWRVRYMVADKFTELQKAVGPEITKTDLVPA----------------FQNLMKAEVRAAASHKVKEFCENLSACRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLK-PEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKW---RVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVYAIREAATSNLKKLVEKFG---KEWAHATIIPKVLAMSGD---PNYLHRMTTLFCINVLSEVCGQDITTKHMLPTGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQ----DQDVDVKYFAQEALTVLSLA------ | |||||||||||||
5 | 4c0oA | 0.10 | 0.10 | 3.54 | 1.69 | CNFpred | ---TVVSLLMTCVEKAGTDEKMLMKVFRCLGSWFN-LLALLFEVLQQTSSNLHEAASDCVCSALYAIENVETNLPLAMQLFQGVLTLETAYHMAV-KVLNYCRIFTELCETFLEKIDLRTLELLLICAHPQYEVVEISFNFWYRLGEHLYKTNDEHGIFKAYIQRLLHALARHCQLHEGVPEETDDFGEFRMRVSDLVKDLIFLIGSMECFAQLYSTLPWEVTEAVLFIMAAIAKSVDPENNPTLVEVLEGVVRLPE-TVHTAVRYTSIELVGEMS-FLDPVLGYLMKGLCE-------------KPLASAAAKAIHNICSVC-NGLLEIARSLLSPEAAVGLLKGTALVLARLPKITECLSELCSVQVMALPTVFLDRLAVIFRHT-HPCQKVIQEIWPVLSETLNKHADNRIVERCCRCLRFAVRCVGKGSAALLQPLVTQMVNVYHSCFLYLGSILVDEYGMERQGLLDMLQALCIPTFQLLEQQGLQNHPDTVDDLFRLATRFIQR-----------SPVTLLRSQVVIPILQWAIASTTLHRDANCSVMRFLRDLIHTGKELIGQVMNQLGQQLVSQLLHTCCFCLPPYTLPDVAEVLWEIMQVDRPTFC | |||||||||||||
6 | 1vt4I | 0.10 | 0.08 | 2.86 | 0.78 | HHsearch-2 | ------------------------------------------------------------MDFET-----GEHQYQYKDILSVFEDAFVDNFCQDMPKSIL--SKEEIDHIIMSKDAVSGTLRLFWTLKQEEMVQKFVEEVLRINYKFLMSPIKTEQPSMMTRMYIEQRDRLYNDNQVFAKYNVSRLQPYL----KLRQALLELDVCLSYKVQCKMNLKNCNSPETVLEMLQKLLYQIDPNRSRIHSIQAELRRLLKYENCNVQNAKAWNAFSCLTTRFKQVTDFLSALDHHSMTPEDLPREVLTTNPRSIIAESIRDGLAT---WDNWKHVNCDK-----LTTIIESSLNVLEPAEYRKMFDRL---------------SVFPPSAHIPTIL--------LSLIWFDVIKSDVMVVVNKLHKYSLVEKQPKETISPSIYLE-------------LKVKLENEYA---LHRSIVDHYNIPKTFDSDLIPPYLDQYFYSHIGHHLKNIEHPER------MTLFRMVFLDFRFLE--QKIRHDSTAWN-ASGSILNT-LQQLKFYKPYICDNDPKERLVNAILDFLPKIEENLICSKYTDLLRIAEDFEEAHKQVQR | |||||||||||||
7 | 1b3uA | 0.09 | 0.08 | 3.20 | 1.60 | Neff-PPAS | QLRLNSIKKLSTIALALGVERTRSELLPFLTDTIDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSD---------DTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLAS--DEQDSVRLLAVEACVNIAQLLP--QEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASV-------IMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAED-AKWRVRLAIIEYMPLLAGQLG---------VEFFDEKLNSLCMAWLVD-------------HVYAIREAATSNLKKLVEKFG---KEWAHATIIPKVLAMSGD--PNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA------ | |||||||||||||
8 | 1vt4I3 | 0.09 | 0.03 | 1.32 | 1.14 | HHsearch | ----------------------------------------------------------------------------------------------------------------------------------EYALHRSIVD-----HYNIPKTFDSDDLPQYFYSHIGHHLLDFRFLEQKIRHDSTAWNASG-----------SILNTLQQLKFYKPYICDKYERLVNAILDFLPKIEENLICSKYTDLLR-IA-L--MAEDE--------------AIFEEAHK---QVQRGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG-GGGGGGG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | |||||||||||||
9 | 5ifeC | 0.09 | 0.08 | 3.24 | 1.78 | PROSPECTOR2 | NLPFRKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILTLEDQERHLLVKVIDRIL---YKLDDLVRPYVHKILVVIEPLLI-----DEDYYARVEGREIISNLAKAAGLATMISTMRPDNMDEYVRNTTARAFAVVASALGKAVCKSKKSWQARHTGIKIVQQIAILMG---------CAILPHLRSLVEIIEHGLVSALAIAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFKIVLKVVKQCCGTDGVEANHFWQHRMALDRRNYRQLVDTTVELANKVGAAEIIDIDHKLEEQLIDGILYAFQEQTTEDSVMLNGFGVKPYLPQICGTVLWRLNNKSAKVRQQAADLIMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTIKDLLPRLTPILKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHNRVCTTVAIAIVAETLPALMNEYRVPELNVQNGVLKSLSFLYIGEMGKDLEDALMDRDLVHRQTASAVVQHMSLGV---YGFGCEDSLNHLLNYVWPNV----FETSPHVIQAVMGALEGLRVAIGP | |||||||||||||
10 | 5u6oA | 0.12 | 0.03 | 1.09 | 0.17 | SAM | --------------------------------------------------IGMMLLLCHWDGCLQFLVPLLQDFPSYALFKAMSHMLCIGYGA-QAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYQGKIFDEENILNELNDPL-----REEIVNFNCRKLVATMPLFANADPN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | |||||||||||||
|
|
References: | |
1. | Wei Zheng, Yang Li, Chengxin Zhang, Robin Pearce, S. M. Mortuza, Yang Zhang. "Deep-learning contact-map guided protein structure prediction in CASP13." Proteins: Structure, Function, and Bioinformatics, 87: 1149-1164 (2019). |