6kjj A 2.49 BS01 D9L A 1 A73 K76 W162 Y164 R166 F287 N302 L320 G321 M322 W324 A68 K71 W157 Y159 R161 F282 N297 L315 G316 M317 W319 A0A0U1X4V6 SNPAFDMKQINALNGHYQTMIDNGDLQCASYMMSRGGEVFAAESLGEFTGGQKEKQTFQLDTIREIGALTKVFTAVAVMQLVEKGLLDLKMPVKLILPAFDKPGFGEIKILHLLTHTAGLSFELDIQKAEGIDLTNEEEWINYLVSTPLEYGVDEAWNYSRTGFVILGIIISKVTGVSYEQYVTKHIIEALGLERTYFYVPDTLKEEVCVISEHECVQLEKSHHPYFPNKATSGLYSSLRDIWKLAEMFRNKGRLKDKKLLGRKTVEAMLRNQIKPGLPFYFFGAPREEGGFGLGINLWPAGDHYFMTEGTFSHLGMGWCGMFSDPAEDFTYVFFTPISEFHPHAVLTPLNIVWAGIELEH 6kjp A 2.06 BS01 D9F A 1 S73 Y164 F287 F288 R292 W304 L320 M322 W324 F346 L352 S67 Y158 F281 F282 R286 W298 L314 M316 W318 F340 L346 A0A0U1X4V6 NPAFDMKQINALNGHYQTMIDNGDLQCASYMMSRGGEVFAAESLGEFTGGQKEKQTFQLDTIREIGSLTKVFTAVAVMQLVEKGLLDLKMPVKLILPAFDKPGFGEIKILHLLTHTAGLSFELDIQKAEGIDLTNEEEWINYLVSTPLEYGVDEAWNYSRTGFVILGIIISKVTGVSYEQYVTKHIIEALGLERTYFYVPDTLKEEVCVISEHECVQLEKSHHPYFPNKATSGLYSSLRDIWKLAEMFRNKGRLKDKKLLGRKTVEAMLRNQIKPGLPFYFFGAPREEGGFGLGINLWPAGDHYFMTEGTFSHLGMGWCGMFSDPAEDFTYVFFTPISEFHPHAVLTPLNIVWAGIEL 6kjq A 2.35 BS01 D9F A 1 A73 F127 W162 Y164 F287 F288 R292 N302 W304 L320 M322 W324 F346 A67 F121 W156 Y158 F281 F282 R286 N296 W298 L314 M316 W318 F340 A0A0U1X4V6 NPAFDMKQINALNGHYQTMIDNGDLQCASYMMSRGGEVFAAESLGEFTGGQKEKQTFQLDTIREIGALTAVFTAVAVMQLVEKGLLDLKMPVKLILPAFDKPGFGEIKILHLLTHTAGLSFELDIQKAEGIDLTNEEEWINYLVSTPLEYGVDEAWNYSRTGFVILGIIISKVTGVSYEQYVTKHIIEALGLERTYFYVPDTLKEEVCVISEHECVQLEKSHHPYFPNKATSGLYSSLRDIWKLAEMFRNKGRLKDKKLLGRKTVEAMLRNQIKPGLPFYFFGAPREEGGFGLGINLWPAGDHYFMTEGTFSHLGMGWCGMFSDPAEDFTYVFFTPISEFHPHAVLTPLNIVWAGIELE 6kjr A 2.36 BS01 D9O A 1 G72 A73 K76 Y164 R166 S238 F287 W304 L320 G321 M322 W324 F346 G66 A67 K70 Y158 R160 S232 F281 W298 L314 G315 M316 W318 F340 A0A0U1X4V6 NPAFDMKQINALNGHYQTMIDNGDLQCASYMMSRGGEVFAAESLGEFTGGQKEKQTFQLDTIREIGALTKVFTAVAVMQLVEKGLLDLKMPVKLILPAFDKPGFGEIKILHLLTHTAGLSFELDIQKAEGIDLTNEEEWINYLVSTPLEYGVDEAWNYSRTGFVILGIIISKVTGVSYEQYVTKHIIEALGLERTYFYVPDTLKEEVCVISEHECVQLEKSHHPYFPNKATSGLYSSLRDIWKLAEMFRNKGRLKDKKLLGRKTVEAMLRNQIKPGLPFYFFGAPREEGGFGLGINLWPAGDHYFMTEGTFSHLGMGWCGMFSDPAEDFTYVFFTPISEFHPHAVLTPLNIVWAGIELE 6kkg A 2.15 BS01 III C 1 E308 M309 A310 Y311 T312 Y318 I320 H322 K325 T326 T327 S328 W329 Y361 Y364 V366 D367 H368 R371 T373 Q374 F375 E8 M9 A10 Y11 T12 Y18 I20 H22 K25 T26 T27 S28 W29 Y61 Y64 V66 D67 H68 R71 T73 Q74 F75 Q9WVQ1 DPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDPIYGTYYVDHINRRTQFENPVLEAKRKLQ 6kkg B 2.15 BS01 III D 1 E308 M309 A310 Y311 T312 Y318 I320 H322 K325 T326 T327 S328 W329 Y361 Y364 V366 H368 R371 T373 Q374 F375 E8 M9 A10 Y11 T12 Y18 I20 H22 K25 T26 T27 S28 W29 Y61 Y64 V66 H68 R71 T73 Q74 F75 Q9WVQ1 DPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDPIYGTYYVDHINRRTQFENPVLEAKRKLQ 6kki A 3.06 BS01 IPT A 1 N26 E29 F30 H115 W119 T146 Q320 M335 F338 S339 F342 N343 N17 E20 F21 H106 W110 T132 Q295 M310 F313 S314 F317 N318 P31122 VAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFTVLVISRIGVAFAHAIFWSITASLAIRMAAQALSLIATGTALAMVLGLPLGRIVGQYFGWRMTFFAIGIGALITLLCLIKLLPSLPLLFRRPALMSIYLLTVVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTL 6kkv A 2.56 BS01 DKR A 1 H27 Y31 Y32 P37 I39 S40 D41 F44 H20 Y24 Y25 P30 I32 S33 D34 F37 6.5.1.2 P9WNV1 QTAPEVLRQWQALAEEVREHQFRYYVRDAPIISDAEFDELLRRLEALEEQHPELRTPDSPTQLVGGAGFATDFEPVDHLERMLSLDNAFTADELAAWAGRIHAEVGDAAHYLCELKIDGVALSLVYREGRLTRASTRGDGRTGEDVTLNARTIADVPERLTPGDDYPVPEVLEVRGEVFFRLDDFQALNASLVEEGKAPFANPRNSAAGSLRQKDPAVTARRRLRMICHGLGHVEGFRPATLHQAYLALRAWGLPVSEHTTLATDLAGVRERIDYWGEHRHEVDHEIDGVVVKVDEVALQRRLGSTSRAPRWAIAYKYPPE 6kmp A 1.31 BS01 KVS B 1 R8 L23 D25 G27 A28 D29 D30 I32 G48 G49 I50 P81 I84 R8 L23 D25 G27 A28 D29 D30 I32 G48 G49 I50 P81 I84 Q903T0 32478251 PQITLWKRPLVTIKIGGQLKEALLDTGADDTIIEEMSLPGRWKPKMVGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPTPINIIGRNLLTQIGATLNF 6kmp B 1.31 BS01 KVS B 1 L23 D25 G27 A28 D29 D30 I32 V47 G48 G49 I50 F53 P81 I82 I84 L23 D25 G27 A28 D29 D30 I32 V47 G48 G49 I50 F53 P81 I82 I84 Q903T0 32478251 PQITLWKRPLVTIKIGGQLKEALLDTGADDTIIEEMSLPGRWKPKMVGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPTPINIIGRNLLTQIGATLNF 6kx1 A 1.77 BS01 III C 1 Y31 W32 R51 V101 F102 D103 Y31 W32 R51 V101 F102 D103 VNLEESGGGLVQPGGSMKLSCVASGFTFSNYWMNWVRQSPEKGLEWVAQIRLKSDNYATHYAESVKGRFTISRDDSKSSVYLQMNNLRAEDTGIYYCTGGVFDYWGQGTTLTVSSSKTTPPSVYPLAPGNSMVTLGCLVKGYFPEPVTVTWNSGALSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSQTVTCNVAHPASSTKVDKKIVPR 6kx1 B 1.77 BS01 III C 1 H31 S32 N33 Y37 H39 L51 Y54 F60 S96 H31 S32 N33 Y37 H39 L51 Y54 F60 S96 DVVMTQTPLSLPVSLGDQASISCRSSQSLVHSNGNTYLHWYLQKPGQSPKLLIYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFCSQSTHVPPWTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 6lk2 A 2.50 BS01 NAD A 1 N42 T44 L45 Y49 D71 E73 K76 G104 G105 V106 D109 T129 T130 L132 D136 S137 K142 N152 C169 T172 L173 P174 E177 N43 T45 L46 Y50 D72 E74 K77 G105 G106 V107 D110 T130 T131 L133 D137 S138 K143 N153 C170 T173 L174 P175 E178 4.2.3.4 X6Q997 32661075 GMEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMMRDKKVMGGKLHLILPTTIGHSEMRSDVDASTVTAAISAC 6lk2 A 2.50 BS02 MG A 1 E184 H248 H265 E185 H245 H262 4.2.3.4 X6Q997 32661075 GMEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMMRDKKVMGGKLHLILPTTIGHSEMRSDVDASTVTAAISAC 6lk2 A 2.50 BS03 7LH A 1 D136 K142 E184 K187 K226 R241 L244 N245 H248 T249 H252 H265 D137 K143 E185 K188 K227 R238 L241 N242 H245 T246 H249 H262 4.2.3.4 X6Q997 32661075 GMEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMMRDKKVMGGKLHLILPTTIGHSEMRSDVDASTVTAAISAC 6lk2 B 2.50 BS01 NAD B 1 N42 T44 L45 D71 E73 K76 G104 G105 V106 D109 T129 T130 L132 D136 S137 K142 N152 C169 T172 L173 P174 E177 N43 T45 L46 D72 E74 K77 G105 G106 V107 D110 T130 T131 L133 D137 S138 K143 N153 C170 T173 L174 P175 E178 4.2.3.4 X6Q997 32661075 GMEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEKEGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMMRDKKVMGGKLHLILPTTIGHSEMRSDVDASTVTAAISA 6lk2 B 2.50 BS02 MG B 1 E184 H248 H265 E185 H247 H264 4.2.3.4 X6Q997 32661075 GMEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEKEGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMMRDKKVMGGKLHLILPTTIGHSEMRSDVDASTVTAAISA 6lk2 B 2.50 BS03 7LH B 1 D136 E184 K187 K226 R241 L244 N245 H248 T249 H252 H265 D137 E185 K188 K227 R240 L243 N244 H247 T248 H251 H264 4.2.3.4 X6Q997 32661075 GMEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEKEGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMMRDKKVMGGKLHLILPTTIGHSEMRSDVDASTVTAAISA 6lk2 C 2.50 BS01 NAD C 1 N42 T44 L45 Y49 D71 E73 K76 G104 G105 V106 D109 T129 T130 L132 D136 S137 K142 K151 N152 C169 T172 E177 N42 T44 L45 Y49 D71 E73 K76 G104 G105 V106 D109 T129 T130 L132 D136 S137 K142 K151 N152 C169 T172 E177 4.2.3.4 X6Q997 32661075 MEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMMLHLILPTTIGHSEMRSDVDASTVTAAI 6lk2 C 2.50 BS02 MG C 1 E184 H248 H265 E184 H244 H261 4.2.3.4 X6Q997 32661075 MEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMMLHLILPTTIGHSEMRSDVDASTVTAAI 6lk2 C 2.50 BS03 7LH C 1 D136 K142 K187 K226 R241 N245 H248 T249 H252 D136 K142 K187 K226 R237 N241 H244 T245 H248 4.2.3.4 X6Q997 32661075 MEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMMLHLILPTTIGHSEMRSDVDASTVTAAI 6lk2 D 2.50 BS01 NAD D 1 N42 T44 L45 D71 E73 K76 G104 G105 V106 D109 T129 T130 L132 D136 S137 K142 N152 C169 T172 L173 P174 E177 N42 T44 L45 D71 E73 K76 G104 G105 V106 D109 T129 T130 L132 D136 S137 K142 N152 C169 T172 L173 P174 E177 4.2.3.4 X6Q997 32661075 MEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADSGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTMQPDDYLPHMHLILPTTIGHSEMRSDVDASTVTAAI 6lk2 D 2.50 BS02 MG D 1 E184 H248 H265 E184 H244 H261 4.2.3.4 X6Q997 32661075 MEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADSGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTMQPDDYLPHMHLILPTTIGHSEMRSDVDASTVTAAI 6lk2 D 2.50 BS03 7LH D 1 D136 K142 N152 K226 R241 L244 N245 H248 H252 H265 D136 K142 N152 K226 R237 L240 N241 H244 H248 H261 4.2.3.4 X6Q997 32661075 MEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADSGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTMQPDDYLPHMHLILPTTIGHSEMRSDVDASTVTAAI 6lla A 1.88 BS01 NAD A 1 N42 L45 D71 E73 K76 G104 G105 V106 D109 T129 T130 L132 D136 K142 N152 C169 T172 L173 E177 N42 L45 D71 E73 K76 G104 G105 V106 D109 T129 T130 L132 D136 K142 N152 C169 T172 L173 E177 4.2.3.4 X6Q997 32661075 MEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEKETSGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMMRDKKVMGGKLHLILPTTIGHSEMRSDVDASTVTAAISACIP 6lla A 1.88 BS02 MG A 1 D136 E184 H248 H265 D136 E184 H248 H265 4.2.3.4 X6Q997 32661075 MEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEKETSGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMMRDKKVMGGKLHLILPTTIGHSEMRSDVDASTVTAAISACIP 6lla B 1.88 BS01 NAD B 1 N42 L45 D71 E73 K76 G104 G105 V106 D109 T129 T130 L132 D136 K142 N152 C169 T172 L173 E177 K226 N43 L46 D72 E74 K77 G105 G106 V107 D110 T130 T131 L133 D137 K143 N153 C170 T173 L174 E178 K227 4.2.3.4 X6Q997 32661075 GMEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEKETSGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMMRDKKVMGGKLHLILPTTIGHSEMRSDVDASTVTAAISACIP 6lla B 1.88 BS02 MG B 1 D136 E184 H248 H265 D137 E185 H249 H266 4.2.3.4 X6Q997 32661075 GMEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEKETSGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMMRDKKVMGGKLHLILPTTIGHSEMRSDVDASTVTAAISACIP 6lla C 1.88 BS01 NAD C 1 N42 T44 L45 D71 E73 K76 G104 G105 V106 D109 T129 T130 D136 K142 N152 C169 T172 L173 E177 N43 T45 L46 D72 E74 K77 G105 G106 V107 D110 T130 T131 D137 K143 N153 C170 T173 L174 E178 4.2.3.4 X6Q997 32661075 GMEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEKETSGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMKLHLILPTTIGHSEMRSDVDASTVTAAISACIP 6lla C 1.88 BS02 MG C 1 D136 E184 H248 H265 D137 E185 H249 H266 4.2.3.4 X6Q997 32661075 GMEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEKETSGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMKLHLILPTTIGHSEMRSDVDASTVTAAISACIP 6lla D 1.88 BS01 NAD D 1 N42 T44 L45 D71 E73 K76 G104 G105 V106 D109 T129 T130 L132 D136 S137 K142 N152 C169 T172 L173 E177 N42 T44 L45 D71 E73 K76 G104 G105 V106 D109 T129 T130 L132 D136 S137 K142 N152 C169 T172 L173 E177 4.2.3.4 X6Q997 32661075 MEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEKETSGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMKLHLILPTTIGHSEMRSDVDASTVTAAISACIP 6lla D 1.88 BS02 MG D 1 D136 E184 H248 H265 D136 E184 H248 H265 4.2.3.4 X6Q997 32661075 MEKVTVTLDERSYPINIAPSLYQQQDAFWPLTAGQRAMIVTNETLAPLYLHKIQTVLEVSGVKVDSIILPDGEQYKSLFIMNDVFTALLEKHHNRDTTLIALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVIDLDCLKTLPKRELSSGLAEVIKYGIILDGEFFSWLEENIDALMALDNQAMAYCIRRCCELKAQVVAADEKETSGLRALLNLGHTFGHAIEAEMGYGVWLHGEAVAAGMVMAAKTAELIGQFTPEQTDRVIALLKRAELPVTGPAKMQPDDYLPHMKLHLILPTTIGHSEMRSDVDASTVTAAISACIP 6lmt A 2.66 BS01 Y01 A 1 M33 S36 F37 W62 L66 V69 M27 S30 F31 W56 L60 V63 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt A 2.66 BS02 Y01 A 2 Y49 I53 L56 V114 F128 N131 Y43 I47 L50 V108 F122 N125 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt A 2.66 BS03 Y01 A 3 M19 Q104 L107 I108 M192 A196 I199 R200 R203 M13 Q98 L101 I102 M186 A190 I193 R194 R197 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt A 2.66 BS04 Y01 A 4 M19 A111 V112 S115 V116 M119 L189 M13 A105 V106 S109 V110 M113 L183 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt A 2.66 BS05 Y01 A 5 M7 A27 L28 A31 S35 M1 A21 L22 A25 S29 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt B 2.66 BS01 Y01 A 1 M19 A111 V112 S115 V116 M119 L189 M13 A105 V106 S109 V110 M113 L183 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt B 2.66 BS02 Y01 B 1 M7 A27 L28 A31 S35 M1 A21 L22 A25 S29 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt B 2.66 BS03 Y01 B 2 M33 S36 F37 W62 L66 V69 M27 S30 F31 W56 L60 V63 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt B 2.66 BS04 Y01 B 3 Y49 I53 L56 V114 F128 N131 Y43 I47 L50 V108 F122 N125 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt B 2.66 BS05 Y01 B 4 M19 Q104 L107 I108 M192 A196 I199 R200 R203 M13 Q98 L101 I102 M186 A190 I193 R194 R197 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt C 2.66 BS01 Y01 B 5 M19 A111 V112 S115 V116 M119 L189 M13 A105 V106 S109 V110 M113 L183 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt C 2.66 BS02 Y01 C 1 M7 A27 L28 A31 S35 M1 A21 L22 A25 S29 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt C 2.66 BS03 Y01 C 2 M33 S36 F37 W62 L66 V69 M27 S30 F31 W56 L60 V63 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt C 2.66 BS04 Y01 C 3 Y49 I53 L56 V114 F128 N131 Y43 I47 L50 V108 F122 N125 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt C 2.66 BS05 Y01 C 4 M19 Q104 L107 I108 M192 A196 I199 R200 R203 M13 Q98 L101 I102 M186 A190 I193 R194 R197 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt D 2.66 BS01 Y01 C 5 M19 A111 V112 S115 V116 M119 L189 M13 A105 V106 S109 V110 M113 L183 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt D 2.66 BS02 Y01 D 1 M7 A27 L28 A31 S35 M1 A21 L22 A25 S29 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt D 2.66 BS03 Y01 D 2 M33 S36 F37 W62 L66 V69 M27 S30 F31 W56 L60 V63 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt D 2.66 BS04 Y01 D 3 Y49 I53 L56 V114 F128 N131 Y43 I47 L50 V108 F122 N125 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt D 2.66 BS05 Y01 D 4 M19 Q104 L107 I108 M192 A196 I199 R200 R203 M13 Q98 L101 I102 M186 A190 I193 R194 R197 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt E 2.66 BS01 Y01 D 5 M19 A111 V112 S115 V116 M119 L189 M13 A105 V106 S109 V110 M113 L183 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt E 2.66 BS02 Y01 E 1 M7 A27 L28 A31 S35 M1 A21 L22 A25 S29 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt E 2.66 BS03 Y01 E 2 M33 S36 F37 W62 L66 V69 M27 S30 F31 W56 L60 V63 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt E 2.66 BS04 Y01 E 3 Y49 I53 L56 V114 F128 N131 Y43 I47 L50 V108 F122 N125 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt E 2.66 BS05 Y01 E 4 M19 Q104 L107 I108 M192 A196 I199 R200 R203 M13 Q98 L101 I102 M186 A190 I193 R194 R197 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt F 2.66 BS01 Y01 E 5 M19 A111 V112 S115 V116 M119 L189 M13 A105 V106 S109 V110 M113 L183 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt F 2.66 BS02 Y01 F 1 M7 A27 L28 A31 S35 M1 A21 L22 A25 S29 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt F 2.66 BS03 Y01 F 2 M33 S36 F37 W62 L66 V69 M27 S30 F31 W56 L60 V63 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt F 2.66 BS04 Y01 F 3 Y49 I53 L56 V114 F128 N131 Y43 I47 L50 V108 F122 N125 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt F 2.66 BS05 Y01 F 4 M19 Q104 L107 I108 M192 A196 I199 R200 R203 M13 Q98 L101 I102 M186 A190 I193 R194 R197 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt G 2.66 BS01 Y01 F 5 M19 A111 V112 S115 V116 M119 L189 M13 A105 V106 S109 V110 M113 L183 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt G 2.66 BS02 Y01 G 1 M7 A27 L28 A31 S35 M1 A21 L22 A25 S29 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt G 2.66 BS03 Y01 G 2 M33 S36 F37 W62 L66 V69 M27 S30 F31 W56 L60 V63 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt G 2.66 BS04 Y01 G 3 Y49 I53 L56 V114 F128 N131 Y43 I47 L50 V108 F122 N125 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt G 2.66 BS05 Y01 G 4 M19 Q104 L107 I108 M192 A196 I199 R200 R203 M13 Q98 L101 I102 M186 A190 I193 R194 R197 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt H 2.66 BS01 Y01 A 6 M33 S36 F37 W62 L66 V69 M27 S30 F31 W56 L60 V63 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt H 2.66 BS02 Y01 G 5 M19 A111 V112 S115 V116 M119 L189 M13 A105 V106 S109 V110 M113 L183 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt H 2.66 BS03 Y01 H 1 M7 A27 L28 A31 S35 M1 A21 L22 A25 S29 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt H 2.66 BS04 Y01 H 2 Y49 I53 L56 V114 F128 N131 Y43 I47 L50 V108 F122 N125 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6lmt H 2.66 BS05 Y01 H 3 M19 Q104 L107 I108 M192 A196 I199 R200 R203 M13 Q98 L101 I102 M186 A190 I193 R194 R197 H2MCM1 MFQFLQSNQESFMNGICGIMALASAQMYSSFEFSCPCMPEYNYTYGIGLLIIPPIWFFLLGFVLNNNVSVLAEEWKRPTGRRTKDPSVLRYMLCSITQRSLIAPAVWVSVTLMDGKSFLCAFSINLDIEKFGNASLVIGMTETEKLKFLARIPCKDLFEDNEVRVAATRYIKCISQACGWMFLLMMTFTAFLIRAIRPCFTQAAFLKTKYWSHYIDIERKMFDETCKEHAKSFAKVCIHQYFENISGEMQNFHR 6m3y A 1.93 BS01 MG A 1 S145 S147 T229 S110 S112 T188 32653644 TDNIRPTYQTDANGTYPTNSWQVTGQQNVINQRGGDQVSGWDNNTIWNGDATDTTNSYLKFGDPNNPDYQIRKYAKETNTPGLYDVYLNVKGNKQQNVKPVDIVLVVDMSGSMENRAGAVRTGVKNFLTSIQNAGLGNYVNVGLIGFSSPGYIGGKSGYISVKLGKAGNASQQQAINGALSPRFQGGTYTQIGLRQGSAMLNADTSGNKKMMILLTDGVPTFSNEVINSEWINGTLYGTNFGSSRDEPGNTARLRWPYTDSSGHYIYDTWPATLGEAKIAKDSGNEVHALGIQLADDDHYMTKEKIRQNMQLITNSPDLYEDADSADAVEAYLNNQAKDIIKNFNTVTDGTITDPIGTQFQYANNQATVTSVGKQTVPASELPSAAIQDGQLTVNHMNLGQDQEVQIHYQVRIKTEDAGFKPDFWYQMNGETLLTPKAGAAAVDFGIPSGRAPATTVYVQKQWRQLSNQSLPDTLNVTVQRKLDPNWQQTLVLKKADNWKASFTAPAYNNQGQSFSYVVKSEDASGIDLSSFISSQNMDQQTATLTLTNQQYGFQFQKKTTDGTDLSADQLKAMQFNLTQYSDNSFQQASKTNAITSTDLQALAPGYYGIQEAAAPTGYQLDGTTYLFQLTSDGQWQYHGTKDNVTSGSVINGQQTLNPVGDKSDDFTVTGDHQQILTLTKYDEPKPSMTLRVIKQDNQSQYLAGAAFTLQPSAGEAETITSSATSEGQAFATKLVADGTYTMSETKAPDGYQSNPAKIAIQVATTGKEATVTIDGEALKPGESKNGYTLAIDGSTITLQAINQPLAILPL 6m48 A 2.50 BS01 MG A 1 S145 S147 T229 S108 S110 T190 32653644 NIRPTYQTDANGTYPTNSWQVTGQQNVINQRGGDQVSGWDNNTIWNGDATDTTNSYLKFGDPNNPDYQIRKYAKETNTPGLYDVYLNVKGNKQQNVKPVDIVLVVDMSGSMESWGTNRAGAVRTGVKNFLTSIQNAGLGNYVNVGLIGFSSPGYIGGKSGYISVKLGKAGNASQQQAINGALSPRFQGGTYTQIGLRQGSAMLNADTSGNKKMMILLTDGVPTFSNEVINSEWINGTLYGTNFGSSRDEPGNTARLRWPYTDSSGHYIYDTWPATLGEAKIAKDSGNEVHALGIQLADDDHYMTKEKIRQNMQLITNSPDLYEDADSADAVEAYLNNQAKDIIKNFNTVTDGTITDPIGTQFQYANNQATVTSVGKQTVPASELPSAAIQDGQLTVNHMNLGQDQEVQIHYQVRIKTEDAGFKPDFWYQMNGETLLTPKAGAAAVDFGIPSGRAPATTVYVQKQWRQLSNQSLPDTLNVTVQRKVADGSLDPNWQQTLVLKKADNWKASFTAPAYNNQGQSFSYVVKSEDASGIDLSSFISSQNMDQQTATLTLTNQQYGFQFQKKTTDGTDLSADQLKAMQFNLTQYSDNSFQQASKTNAITSTDLQALAPGYYGIQEAAAPTGYQLDGTTYLFQLTSDGQWQYHGTKDNVTSGSVINGQQTLNPVGDKSDDFTVTGDHQQILTLTKYDEPKPSMTLRVIKQDNQSQYLAGAAFTLQPSAGEAETITSSATSEGQAFATKLVADGTYTMSETKAPDGYQSNPAKIAIQVATTGKEATVTIDGEALKPGESKNGYTLAIDGSTITLQAINQPL 6m48 B 2.50 BS01 MG B 1 S145 S147 D258 S109 S111 D222 32653644 DNIRPTYQTDANGTYPTNSWQVTGQQNVINQRGGDQVSGWDNNTIWNGDATDTTNSYLKFGDPNNPDYQIRKYAKETNTPGLYDVYLNVKGNKQQNVKPVDIVLVVDMSGSMESNRWGTNRAGAVRTGVKNFLTSIQNAGLGNYVNVGLIGFSSPGYIGGKSGYISVKLGKAGNASQQQAINGALSPRFQGGTYTQIGLRQGSAMLNADTSGNKKMMILLTDGVPTFSNEVINSEWINGTLYGTNFGSSRDEPGNTARLRWPYTDSSGHYIYDTWPATLGEAKIAKDSGNEVHALGIQLADDDHYMTKEKIRQNMQLITNSPDLYEDADSADAVEAYLNNQAKDIIKNFNTVTDGTITDPIGTQFQYANNQATVTSVGKQTVPASELPSAAIQDGQLTVNHMNLGQDQEVQIHYQVRIKTEDAGFKPDFWYQMNGETLLTPKAGAAAVDFGIPSGRAPATTVYVQKQWRQLSNQSLPDTLNVTVQRKVADGSLDPNWQQTLVLKKADNWKASFTAPAYNNQGQSFSYVVKSEDLSSFISSQNMDQQTATLTLTNQQYGFQFQKKTTDGTDLSADQLKAMQFNLTQYSDNSFQQASKTNAITSTDLQALAPGYYGIQEAAAPTGYQLDGTTYLFQLTSDGQWQYHGTKDNVTSGSVINGQQTLNPVGDKSDDFTVTGDHQQILTLTKYDEPKPSMTLRVIKQDNQSQYLAGAAFTLQPSAETITSSATSEGQAFATKLVADGTYTMSETKAPDGYQSNPAKIAIQVATTGKEATVTDGEALKPGESKNGYTLAIDGSTITLQAINQPLAILPL 6ntm A 2.55 BS01 FUC C 1 S347 D349 S341 D343 3.1.1.7 P22303 EDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSA 6ntm A 2.55 BS02 L0S A 1 W86 G121 G122 Y133 E202 S203 A204 W236 F295 F297 Y337 H447 W83 G118 G119 Y130 E199 S200 A201 W233 F289 F291 Y331 H441 3.1.1.7 P22303 EDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSA 6ntm A 2.55 BS03 HI6 A 1 Y72 D74 Y124 V282 E285 W286 Y337 Y341 Y69 D71 Y121 V276 E279 W280 Y331 Y335 3.1.1.7 P22303 EDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSA 6ntm B 2.55 BS01 L0S B 1 W86 G121 G122 Y133 E202 S203 A204 F295 F297 Y337 H447 W82 G117 G118 Y129 E198 S199 A200 F286 F288 Y328 H438 3.1.1.7 P22303 DAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSA 6ntm B 2.55 BS02 HI6 B 1 Y72 Y124 W286 F295 F297 S298 Y337 F338 Y341 Y68 Y120 W277 F286 F288 S289 Y328 F329 Y332 3.1.1.7 P22303 DAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSA 6oqi A 2.00 BS01 N14 A 1 I10 G11 V18 A31 F80 E81 L83 D86 Q131 N132 L134 D145 I11 G12 V19 A32 F72 E73 L75 D78 Q123 N124 L126 D137 2.7.11.22 P24941 FMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL 6oql A 2.71 BS01 N1A A 1 I19 G20 Y24 V27 A41 K43 V77 F98 E99 H100 V101 T107 Q149 L152 A162 D163 I9 G10 Y14 V17 A31 K33 V60 F73 E74 H75 V76 T82 Q124 L127 A137 D138 2.7.11.22 Q00534 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVPLSTIREVAVLRHLETFEHPNVVRLFDVCTKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLAVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQ 6oqo A 1.98 BS01 N1J A 1 I19 Y24 V27 A41 K43 F98 E99 V101 Q149 L152 D163 I9 Y14 V17 A31 K33 F79 E80 V82 Q130 L133 D144 2.7.11.22 Q00534 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLAVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQ 6pup A 1.89 BS01 MN A 1 D128 D130 E131 D48 D50 E51 B6K6D6 TDISACSINIFYSTLGGSTQKFAEHVADRIRSSLQTELVEILNLDYIDLDEYFSKGNSNTVYLVLLPSYAIESSIDYFLSALQTTIDDFRIVARPLEKLRGFAVLGFGDFEQYAGDLFCYQAIAADQRLAKLGAQRIAPLGVVNVKLEKAQVYEAMEAWTDLFLQYAKE 6pup A 1.89 BS02 MN A 2 D128 D130 E131 D48 D50 E51 B6K6D6 TDISACSINIFYSTLGGSTQKFAEHVADRIRSSLQTELVEILNLDYIDLDEYFSKGNSNTVYLVLLPSYAIESSIDYFLSALQTTIDDFRIVARPLEKLRGFAVLGFGDFEQYAGDLFCYQAIAADQRLAKLGAQRIAPLGVVNVKLEKAQVYEAMEAWTDLFLQYAKE 6pup A 1.89 BS03 FMN A 1 T94 L95 G96 G97 S98 T99 P147 S148 Y149 A150 G188 D189 Y193 L197 F198 C199 Y200 V225 T14 L15 G16 G17 S18 T19 P67 S68 Y69 A70 G108 D109 Y113 L117 F118 C119 Y120 V145 B6K6D6 TDISACSINIFYSTLGGSTQKFAEHVADRIRSSLQTELVEILNLDYIDLDEYFSKGNSNTVYLVLLPSYAIESSIDYFLSALQTTIDDFRIVARPLEKLRGFAVLGFGDFEQYAGDLFCYQAIAADQRLAKLGAQRIAPLGVVNVKLEKAQVYEAMEAWTDLFLQYAKE 6pwy A 1.81 BS01 DTP A 1 Q77 T78 R134 H143 Y261 D265 R317 H321 Y325 Q38 T39 R95 H104 Y222 D226 R278 H282 Y286 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSQVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTP 6pwy A 1.81 BS02 GTP A 1 L83 V84 P86 R404 K409 R534 L44 V45 P47 R365 K370 R479 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSQVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTP 6pwy A 1.81 BS03 DTP A 2 V84 Y85 V271 H327 K409 V45 Y46 V232 H288 K370 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSQVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTP 6pwy A 1.81 BS04 DTP B 1 R282 K305 D309 K493 R243 K266 D270 K443 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSQVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTP 6pwy A 1.81 BS05 GTP D 1 H44 I45 I46 D65 Q70 R73 F93 H5 I6 I7 D26 Q31 R34 F54 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSQVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTP 6pwy A 1.81 BS06 DTP D 1 I45 N47 I6 N8 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSQVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTP 6pwy B 1.81 BS01 DTP A 3 R282 K305 D309 K493 R243 K266 D270 K447 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATQLKGAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTPRKRSPQ 6pwy B 1.81 BS02 DTP B 2 Q77 T78 H143 H159 Y261 D265 R317 H321 Y325 Q38 T39 H104 H120 Y222 D226 R278 H282 Y286 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATQLKGAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTPRKRSPQ 6pwy B 1.81 BS03 GTP B 1 L83 V84 P86 A329 R404 K409 R534 L44 V45 P47 A290 R365 K370 R482 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATQLKGAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTPRKRSPQ 6pwy B 1.81 BS04 DTP B 1 V84 Y85 V271 K323 H327 K409 V45 Y46 V232 K284 H288 K370 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATQLKGAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTPRKRSPQ 6pwy B 1.81 BS05 GTP C 1 H44 I45 I46 D65 Q70 R73 F93 H5 I6 I7 D26 Q31 R34 F54 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATQLKGAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTPRKRSPQ 6pwy B 1.81 BS06 DTP C 1 I45 N47 I6 N8 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATQLKGAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTPRKRSPQ 6pwy D 1.81 BS01 GTP A 1 H44 I45 I46 D65 Q70 R73 F93 H5 I6 I7 D26 Q31 R34 F54 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENAAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSQVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTP 6pwy D 1.81 BS02 DTP A 4 I45 N47 I6 N8 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENAAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSQVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTP 6pwy D 1.81 BS03 DTP D 2 Q77 T78 R134 H143 H159 D257 Y261 D265 R317 H321 Y325 Q38 T39 R95 H104 H120 D218 Y222 D226 R278 H282 Y286 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENAAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSQVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTP 6pwy D 1.81 BS04 GTP D 1 L83 V84 P86 R404 K409 R534 L44 V45 P47 R365 K370 R478 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENAAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSQVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTP 6pwy D 1.81 BS05 DTP D 1 V84 Y85 V271 K323 H327 K409 V45 Y46 V232 K284 H288 K370 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENAAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSQVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTP 6pwy D 1.81 BS06 DTP C 1 R282 K305 D309 K493 R243 K266 D270 K442 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENAAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSQVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTP 6pwy C 1.81 BS01 GTP B 1 H44 I45 I46 D65 Q70 R73 F93 H5 I6 I7 D26 Q31 R34 F54 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATQLKGAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTPRKRSPQ 6pwy C 1.81 BS02 DTP B 1 I45 N47 I6 N8 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATQLKGAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTPRKRSPQ 6pwy C 1.81 BS03 DTP D 1 R282 K305 D309 K493 R243 K266 D270 K447 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATQLKGAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTPRKRSPQ 6pwy C 1.81 BS04 DTP C 2 Q77 T78 H143 H159 Y261 D265 R317 H321 Y325 Q38 T39 H104 H120 Y222 D226 R278 H282 Y286 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATQLKGAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTPRKRSPQ 6pwy C 1.81 BS05 GTP C 1 L83 V84 P86 R404 K409 R534 L44 V45 P47 R365 K370 R482 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATQLKGAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTPRKRSPQ 6pwy C 1.81 BS06 DTP C 1 V84 Y85 V271 K323 H327 K409 V45 Y46 V232 K284 H288 K370 Q09374 MEPKHIINDNVYGTVKVPRPIDKLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLNITESDLICTSVAALLRNVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPEIKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDALINAGDFLKYKGSNGELYSLKNVTEDVDAFLKTTDYVEQEILNSQITDPKMIEAQTALLKIQRREIGCKLGYFEMNPENATQLKGAAEVVKKVGQKMKEILEQMDDTEEMDGKLKDIQFTVMHSVLGRGLDDKTHPIERQIFYDGKPSVVGFYPSEDYVINNCPRMATKWEIFVMGDRSLRKEPLLADRVKRALQLAGESEKFLTPRKRSPQ 6pwz D 3.00 BS01 P6D D 1 Y65 F83 R174 Y46 F64 R155 2.7.1.48 Q9BZX2 GEPFLIGVSGGTASGKSSVCAKIVQLLGQNDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNG 6pwz E 3.00 BS01 P6D E 1 A76 D84 F114 R174 A59 D67 F97 R157 2.7.1.48 Q9BZX2 GEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILN 6pwz H 3.00 BS01 P6D H 1 D62 D84 I137 R174 Q184 D44 D61 I111 R148 Q158 2.7.1.48 Q9BZX2 EPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNG 6pxf A 1.85 BS01 J0V A 1 N18 G20 Y89 N187 N18 G20 Y89 N187 3.4.22.38 P43235 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLAPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 6pxf A 1.85 BS02 J0V A 2 Q76 K77 R79 R108 Q76 K77 R79 R108 3.4.22.38 P43235 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLAPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 6pxf A 1.85 BS03 J0V A 3 K77 R79 K103 K106 K77 R79 K103 K106 3.4.22.38 P43235 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLAPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 6pxf A 1.85 BS04 J0V A 4 R8 N190 K191 R8 N190 K191 3.4.22.38 P43235 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLAPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 6pxi E 3.45 BS01 ADP E 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 L335 I343 A392 R393 H15 I16 I17 T58 G59 V60 G61 K62 T63 E64 L266 I274 A323 R324 C3SIX7 SEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAEPSAARQAFRKKLREGQKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDQIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxi F 3.45 BS01 ADP F 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 L335 I343 A392 R393 H15 I16 I17 T58 G59 V60 G61 K62 T63 E64 L259 I267 A316 R317 C3SIX7 SEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAPSAARQAFRKKLREIMAPPGMEEMTSQLQSMFQNLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDQIDKICKRGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxk G 3.65 BS01 ADP G 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 L335 I343 A392 R393 H17 I18 I19 T60 G61 V62 G63 K64 T65 E66 L266 I274 A323 R324 C3SIX7 HHSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPVEIMAPPGMEEMTSQLQSMFQNLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxk H 3.65 BS01 ADP H 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H396 H17 I18 I19 T60 G61 V62 G63 K64 T65 E66 I292 A341 R342 H345 C3SIX7 HHSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNEPSAARQAFRKKLREGQLDDKEIEIDLARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxk I 3.65 BS01 ADP I 1 I17 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 I18 I19 T60 G61 V62 G63 K64 T65 E66 I311 A360 R361 C3SIX7 HHSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPSAARQAFRKKLREGQLDDDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxk J 3.65 BS01 ADP J 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H396 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I221 A270 R271 H274 C3SIX7 HSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxk K 3.65 BS01 ADP K 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 L335 I343 A392 R393 H396 H17 I18 I19 T60 G61 V62 G63 K64 T65 E66 L321 I329 A378 R379 H382 C3SIX7 HHSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxk L 3.65 BS01 ADP L 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H396 H17 I18 I19 T60 G61 V62 G63 K64 T65 E66 I294 A343 R344 H347 C3SIX7 HHSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWEPSAARQAFRKKLREGQLDDKEIEIDKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxk A 3.65 BS01 ADP A 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 L335 I343 A392 R393 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 L312 I320 A369 R370 C3SIX7 HSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAEPSAARQAFRKKLREGQLDDKEIEIDLAPMGVEIMAPPGMEEMTSQLQSMFQNLKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxk B 3.65 BS01 ADP B 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H17 I18 I19 T60 G61 V62 G63 K64 T65 E66 I297 A346 R347 C3SIX7 HHSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNPSAARQAFRKKLREGQLDDKEIEIDLAAKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxk C 3.65 BS01 ADP C 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H396 H17 I18 I19 T60 G61 V62 G63 K64 T65 E66 I325 A374 R375 H378 C3SIX7 HHSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxk D 3.65 BS01 ADP D 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 L335 I343 A392 R393 H396 H17 I18 I19 T60 G61 V62 G63 K64 T65 E66 L227 I235 A284 R285 H288 C3SIX7 HHSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVKEVDSIIRDLTDAAVKMVRVQAIEKNRYKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxk E 3.65 BS01 ADP E 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 L335 I343 A392 R393 H17 I18 I19 T60 G61 V62 G63 K64 T65 E66 L318 I326 A375 R376 C3SIX7 HHSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxk F 3.65 BS01 ADP F 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H396 H17 I18 I19 T60 G61 V62 G63 K64 T65 E66 I288 A337 R338 H341 C3SIX7 HHSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPPSAARQAFRKKLREGQLDDKEIEIKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxl A 3.74 BS01 ADP A 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H396 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I269 A318 R319 H322 C3SIX7 HSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAPSAARQAFRKKLREGQMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxl B 3.74 BS01 ADP B 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H17 I18 I19 T60 G61 V62 G63 K64 T65 E66 I317 A366 R367 C3SIX7 HHSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPSAARQAFRKKLREGQLDDKEIEIDLAAMGVEIMAPPGMEEMTSQLQSMFQNLKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxl C 3.74 BS01 ADP C 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H396 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I289 A338 R339 H342 C3SIX7 HSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPEPSAARQAFRKKLREGQLDDKEIEIDLAARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxl D 3.74 BS01 ADP D 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 L335 I343 A392 R393 H396 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 L293 I301 A350 R351 H354 C3SIX7 HSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPSAARQAFRKKLREGQLDDKMGVEIMAPPGMEEMTSQLQSMFQNLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxl E 3.74 BS01 ADP E 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 L335 I343 A392 R393 H396 H14 I15 I16 T57 G58 V59 G60 K61 T62 E63 L227 I235 A284 R285 H288 C3SIX7 EMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxl F 3.74 BS01 ADP F 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H396 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I310 A359 R360 H363 C3SIX7 HSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPPSAARQAFRKKLREGQLDDKEIEIIMAPPGMEEMTSQLQSMFQNLQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxl G 3.74 BS01 ADP G 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 L335 I343 A392 R393 H15 I16 I17 T58 G59 V60 G61 K62 T63 E64 L311 I319 A368 R369 C3SIX7 SEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPEPSAARQAFRKKLRLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxl H 3.74 BS01 ADP H 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H396 H15 I16 I17 T58 G59 V60 G61 K62 T63 E64 I295 A344 R345 H348 C3SIX7 SEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNEPSAARQAFRKKLREGQLDDKEIEIDLAAKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxl I 3.74 BS01 ADP I 1 H16 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H396 H16 I18 T59 G60 V61 G62 K63 T64 E65 I276 A325 R326 H329 C3SIX7 HSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEEDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxl J 3.74 BS01 ADP J 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H396 H17 I18 I19 T60 G61 V62 G63 K64 T65 E66 I231 A280 R281 H284 C3SIX7 HHSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxl K 3.74 BS01 ADP K 1 H16 I17 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H17 I18 I19 T60 G61 V62 G63 K64 T65 E66 I329 A378 R379 C3SIX7 HHSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxl L 3.74 BS01 ADP L 1 H16 I18 T59 G60 V61 G62 K63 T64 E65 I343 A392 R393 H396 H17 I19 T60 G61 V62 G63 K64 T65 E66 I296 A345 R346 H349 C3SIX7 HHSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNEQQQEPSAARQAFRKKLREGQLDDKEIEIDKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL 6pxr L 1.56 BS01 III A 1 Y37 E39 K55 G96 W101 Y37 E39 K55 G96 W101 A2NHM3 DVLMTQTPLSLPVSLGDQASISCKSSQSIVHSNGNTYLEWYLQKPGQSPKLLVYKVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGTYYCFQGSLVPWAFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 6pxr H 1.56 BS01 III A 1 G33 T50 S52 S53 S54 R57 Y59 W100 D101 G102 A103 G32 T49 S51 S52 S53 R56 Y58 W99 D100 G101 A102 VHLVESGGALVKPGGSLKLSCAASGFSFSKYGMSWVRQTPDKRLEWVATISSSGSRTYYPDSVKGQFTISRDNAKNTLYLQMSSLKSEDTAMYYCSISWDGAMDYWGQGTSVTVSSAKTTPPSVYPLAPGSSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRD 6py1 A 1.70 BS01 CA A 1 V218 N220 E224 E305 V40 N42 E46 E127 Q8IUN9 TSCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGSAYTWMGLSDPEGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPDGRWNDDVCQRPYHWVCEAGL 6py1 A 1.70 BS02 CA A 2 D243 D270 E280 D281 D65 D92 E102 D103 Q8IUN9 TSCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGSAYTWMGLSDPEGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPDGRWNDDVCQRPYHWVCEAGL 6py1 A 1.70 BS03 CA A 3 Q267 D269 E280 N292 D293 Q89 D91 E102 N114 D115 Q8IUN9 TSCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGSAYTWMGLSDPEGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPDGRWNDDVCQRPYHWVCEAGL 6py1 A 1.70 BS04 CA A 4 E206 Q210 H215 L216 V251 E28 Q32 H37 L38 V73 Q8IUN9 TSCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGSAYTWMGLSDPEGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPDGRWNDDVCQRPYHWVCEAGL 6pye A 1.48 BS01 P5Y A 1 H463 P464 S531 H573 H574 G582 F583 D612 H614 F643 N645 D705 L712 Y745 H22 P23 S90 H132 H133 G141 F142 D171 H173 F202 N204 D264 L271 Y304 A7YT55 PITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLR 6pye A 1.48 BS02 ZN A 1 D612 H614 D705 D171 H173 D264 A7YT55 PITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLR 6pye B 1.48 BS01 P5Y B 1 H463 P464 S531 H573 H574 G582 F583 D612 H614 F643 N645 D705 L712 Y745 H22 P23 S90 H132 H133 G141 F142 D171 H173 F202 N204 D264 L271 Y304 A7YT55 PITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLR 6pye B 1.48 BS02 ZN B 1 D612 H614 D705 D171 H173 D264 A7YT55 PITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLR 6sxx A 2.01 BS01 LXQ A 1 F1111 V1115 L1120 I1122 Y1125 A1164 Y1167 N1168 V1174 F28 V32 L37 I39 Y42 A81 Y84 N85 V91 2.3.1.48 Q92793 IFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSL 6sxx B 2.01 BS01 LXQ B 1 P1110 V1115 L1120 Y1167 N1168 V1174 P27 V32 L37 Y84 N85 V91 2.3.1.48 Q92793 IFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSL 6t1z A 2.90 BS01 HT1 A 1 A53 V54 N147 I231 M232 F234 D235 A269 C270 E327 M358 P359 S362 A53 V54 N147 I224 M225 F227 D228 A256 C257 E314 M345 P346 S349 Q48658 GKEFWNLDKNLQLRLGIVFLGAFSYGTVFSSMTIYYNQYLGSAITGILLALSAVATFVAGILAGFFADRNGRKPVMVFGTIIQLLGAALAIASNLPGHVNPWSTFIAFLLISFGYNFVITAGNAMIIDASNAENRKVVFMLDYWAQNLSVILGAALGAWLFRPAFEALLVILLLTVLVSFFLTTFVMTETFKPTDNIFQAYKTVLQDKTYMIFMGANIATTFIIMQFDNFLPVHLSNSFKTITYGQRMLTIYLILACVLVVLLMTTLNRLTKDWSHQKGFIWGSLFMAIGMIFSFLTTTFTPIFIAGIVYTLGEIVYTPSVQTLGADLMNPEKIGSYNGVAAIKMPIASILAGLLVSISPMIKAIGVSLVLALTEVLAIILVLVAVNRHQKTK 6t5j A 1.60 BS01 MKB A 1 G15 V16 G17 R34 Q44 L45 G48 Y90 Y92 T94 F135 G137 L138 G6 V7 G8 R25 Q35 L36 G39 Y81 Y83 T85 F126 G128 L129 3.6.1.9 Q9NV35 32690945 RRPGVGVGVVVTSCKHPRCVLLGKRKGSVGAGSFQLPGGHLEFGETWEECAQRETWEEAALHLKNVHFASVVNSFIEKENYHYVTILMKGEVDVTHDSEPKNVEPEKNESWEWVPWEELPPLDQLFWGLRCLKEQGYDPFKEDLNHLVGYKGNH 6t5j A 1.60 BS02 MG A 1 E63 E67 E54 E58 3.6.1.9 Q9NV35 32690945 RRPGVGVGVVVTSCKHPRCVLLGKRKGSVGAGSFQLPGGHLEFGETWEECAQRETWEEAALHLKNVHFASVVNSFIEKENYHYVTILMKGEVDVTHDSEPKNVEPEKNESWEWVPWEELPPLDQLFWGLRCLKEQGYDPFKEDLNHLVGYKGNH 6t5j B 1.60 BS01 MKB B 1 G15 V16 G17 R34 Q44 L45 G48 Y90 Y92 T94 F135 W136 G137 L138 G6 V7 G8 R25 Q35 L36 G39 Y81 Y83 T85 F126 W127 G128 L129 3.6.1.9 Q9NV35 32690945 RRPGVGVGVVVTSCKHPRCVLLGKRKGSVGAGSFQLPGGHLEFGETWEECAQRETWEEAALHLKNVHFASVVNSFIEKENYHYVTILMKGEVDVTHDSEPKNVEPEKNESWEWVPWEELPPLDQLFWGLRCLKEQGYDPFKEDLNHLVGYKGNH 6t5j B 1.60 BS02 MG B 1 E63 E67 E54 E58 3.6.1.9 Q9NV35 32690945 RRPGVGVGVVVTSCKHPRCVLLGKRKGSVGAGSFQLPGGHLEFGETWEECAQRETWEEAALHLKNVHFASVVNSFIEKENYHYVTILMKGEVDVTHDSEPKNVEPEKNESWEWVPWEELPPLDQLFWGLRCLKEQGYDPFKEDLNHLVGYKGNH 6tj0 B 2.20 BS01 C2E B 1 R415 D418 L431 S432 C434 D438 T441 A442 H445 I446 R193 D196 L209 S210 C212 D216 T219 A220 H223 I224 P37657 SDEKRILSNVAVLEGAPPLSEHWQLFNNNEVLFNEARTAQAATVVFSLQQNAQIEPLARSIHTLRRQRGSAMKILVRENTASLRATDERLLLACGANMVIPWNAPLSRCLTMIESVQGQKFSRYVPEDITTLLSMTQPLKLRGFQKWDVFCNAVNNMMNNPLLPAHGKGVLVALRPVPGIRVEQALTLCRPNRTGDIMTIGGNRLVLFLSFCRINDLDTALNHIFPLPTGDIFSNRMVWFEDDQISAELVQMR 6twe A BS01 CU1 A 1 H1 H90 H1 H90 Q62YN7 HGFIEKPGSRAALCSEAFGFLNLNCGSVMYEPQSLEAKKGFPHSGPADGQIASAGGLFGGILDQQSENRWFKHIMTGGEHTFTWTYTAPHNTSQWHYYITKKGWDPDKPLKRADFELIGAVPHDGSPASRNLSHHIYIPEDRLGYHVILAVWDVADTENAFYQVIDVDLVNK 6ubg A 1.70 BS01 III B 1 E32 L33 G34 F35 S36 I37 S38 R44 G45 N46 P47 T58 R59 Q61 L89 E93 K97 E14 L15 G16 F17 S18 I19 S20 R26 G27 N28 P29 T40 R41 Q43 L71 E75 K79 Q96RT1 SSMEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIRLEEAERLLKTFQNTVELIIVREVS 6ubh A 1.80 BS01 III E 1 E32 L33 G34 F35 S36 I37 R44 T58 R59 M89 V93 L96 E13 L14 G15 F16 S17 I18 R25 T39 R40 M70 V74 L77 Q96RT1 SMEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIEMGQAVSLLKTFQNTVELIIVRE 6ubh B 1.80 BS01 III F 1 E32 L33 G34 F35 S36 I37 S38 R44 T58 R59 M89 V93 E14 L15 G16 F17 S18 I19 S20 R26 T40 R41 M71 V75 Q96RT1 SSMEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIEMGQAVSLLKTFQNTVELIIVRE 6ubh C 1.80 BS01 III G 1 L33 G34 F35 S36 I37 S38 R44 T58 R59 Q61 V93 L15 G16 F17 S18 I19 S20 R26 T40 R41 Q43 V75 Q96RT1 SSMEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIEMGQAVSLLKTFQNTVELIIVRE 6ubh D 1.80 BS01 III H 1 L33 G34 F35 S36 I37 S38 R44 T58 R59 Q61 V93 K97 L15 G16 F17 S18 I19 S20 R26 T40 R41 Q43 V75 K79 Q96RT1 SSMEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIEMGQAVSLLKTFQNTVELIIVRE 6ubs A 3.33 BS01 PIO A 1 F319 S320 F289 S290 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6ubs B 3.33 BS01 PIO B 1 F319 S320 F289 S290 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6ubs C 3.33 BS01 PIO C 1 F319 S320 F289 S290 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6ubs D 3.33 BS01 PIO D 1 F319 S320 F289 S290 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6ubs E 3.33 BS01 PIO E 1 F319 S320 F289 S290 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6ubt A 3.55 BS01 GLY A 1 R89 L141 S153 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSED 6ubt A 3.55 BS02 GLY B 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSED 6ubt B 3.55 BS01 GLY B 1 R89 L141 S153 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSED 6ubt B 3.55 BS02 GLY C 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSED 6ubt C 3.55 BS01 GLY C 1 R89 L141 S153 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSED 6ubt C 3.55 BS02 GLY D 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSED 6ubt D 3.55 BS01 GLY D 1 R89 L141 S153 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSED 6ubt D 3.55 BS02 GLY E 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSED 6ubt E 3.55 BS01 GLY A 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSED 6ubt E 3.55 BS02 GLY E 1 R89 L141 S153 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSED 6ud3 A 3.50 BS01 GLY A 1 R89 L141 S153 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDI 6ud3 A 3.50 BS02 GLY B 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDI 6ud3 C 3.50 BS01 GLY C 1 R89 L141 S153 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDI 6ud3 C 3.50 BS02 GLY D 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDI 6ud3 E 3.50 BS01 GLY A 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDI 6ud3 E 3.50 BS02 GLY E 1 R89 L141 S153 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDI 6ud3 D 3.50 BS01 GLY E 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDI 6ud3 D 3.50 BS02 GLY D 1 R89 L141 S153 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDI 6ud3 B 3.50 BS01 GLY C 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDI 6ud3 B 3.50 BS02 GLY B 1 R89 L141 S153 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDI 6umq A 1.85 BS01 MG A 1 D253 N254 D291 D227 N228 D265 3.1.3.-,2.1.1.- Q9H993 32682077 VPASLSGQDVGSFAYLTIKDRIPQILTKVIDTLHRHKSEFFEKHGEEGVEAEKKAISLLSKLRNELQTDKPFIPLVEKFVDTDIWNQYLEYQQSLLNESDGKSRWFYSPWLLVECYMYRRIHEAIIQSPPIDYFDVFKESKEQNFYGSQESIIALCTHLQQLIRTIEDLDENQLKDEFFKLLQISLWLEDLKPFILLNDMEHLWSLLSNCKKTREKASATRVYIVLDNSGFELVTDLILADFLLSSELATEVHFYGKTIPWFVSDTTIHDFNWLIEQVKHSNHKWMSKCGADWEEYIKMGKWVYHNHIFWTLPHEYCAMPQVAPDLYAELQKAHLILFKGDLNYRKLTGDRKWEFSVPFHQALNGFHPAPLCTIRTLKAEIQVGLQPGQGEQLLASEPSWWTTGKYGIFQYDGPL 6umq B 1.85 BS01 MG B 1 D253 N254 D291 D227 N228 D265 3.1.3.-,2.1.1.- Q9H993 32682077 VPASLSGQDVGSFAYLTIKDRIPQILTKVIDTLHRHKSEFFEKHGEEGVEAEKKAISLLSKLRNELQTDKPFIPLVEKFVDTDIWNQYLEYQQSLLNESDGKSRWFYSPWLLVECYMYRRIHEAIIQSPPIDYFDVFKESKEQNFYGSQESIIALCTHLQQLIRTIEDLDENQLKDEFFKLLQISLWLEDLKPFILLNDMEHLWSLLSNCKKTREKASATRVYIVLDNSGFELVTDLILADFLLSSELATEVHFYGKTIPWFVSDTTIHDFNWLIEQVKHSNHKWMSKCGADWEEYIKMGKWVYHNHIFWTLPHEYCAMPQVAPDLYAELQKAHLILFKGDLNYRKLTGDRKWEFSVPFHQALNGFHPAPLCTIRTLKAEIQVGLQPGQGEQLLASEPSWWTTGKYGIFQYDGPL 6uoe H 1.80 BS01 III P 1 H32 S52 D53 T55 N56 R94 G96 Y97 C98 R100B C100C Y100D S100E Q100G H31 S51 D53 T55 N56 R97 G99 Y100 C101 R105 C106 Y107 S108 Q110 P0DOX5 VQLVESGGGVVQPGRSLRLSCAASGFTFSNHGLHWVRQAPGKGLEWVAVVSKDGTNEHYADSVRGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAREGYCGDDRCYSGQPDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP 6uoe L 1.80 BS01 III P 1 Y32 Y49 R91 W94 Y32 Y49 R91 W94 P0DOX7 EIVLTQSPATLSLSPGERATLSCRASQSVGRYLAWYQQKPGQAPRLLIYDSSNRATGVPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQRSHWPPLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6uri N 3.00 BS01 III D 1 S34 R35 D36 L37 E38 H40 N47 N51 N52 L76 P78 M79 T80 Y81 F121 D123 W124 N126 L137 T138 F139 H193 F203 S1 R2 D3 L4 E5 H7 N8 N12 N13 L37 P39 M40 T41 Y42 F82 D84 W85 N87 L98 T99 F100 H154 F164 Q90VU7 SRDLEKHNTAANNAACAWLEAQEEEEVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGVRYPLTFGWCYKLVPVEPDKVEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHVARELHPEYF 6urq A 2.05 BS01 III D 1 R368 S370 L375 G378 Y379 L403 N408 Y412 H414 D432 W434 F436 E441 R447 R36 S38 L43 G46 Y47 L71 N76 Y80 H82 D100 W102 F104 E109 R115 2.4.2.30,2.4.2.- O95271 EYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSE 6urq B 2.05 BS01 III C 1 R368 S370 G378 Y379 L403 N408 Y412 H414 D432 W434 F436 E441 R447 R34 S36 G44 Y45 L69 N74 Y78 H80 D98 W100 F102 E107 R113 2.4.2.30,2.4.2.- O95271 KKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSE 6vi5 A 1.60 BS01 FE2 A 1 H51 E57 H95 E110 H51 E57 H95 E110 1.13.11.6 Q1LCS4 MLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6vi5 A 1.60 BS02 FE2 A 2 C125 C128 C162 C165 C125 C128 C162 C165 1.13.11.6 Q1LCS4 MLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6vi6 A 1.90 BS01 FE2 A 1 H51 E57 H95 E110 H51 E57 H95 E110 1.13.11.6 Q1LCS4 MLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6vi6 A 1.90 BS02 FE2 A 2 C125 C128 C162 C165 C125 C128 C162 C165 1.13.11.6 Q1LCS4 MLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6vi6 A 1.90 BS03 3HA A 1 V41 R47 H51 E57 F59 P97 R99 E110 I142 V41 R47 H51 E57 F59 P97 R99 E110 I142 1.13.11.6 Q1LCS4 MLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6vi8 A 1.95 BS01 FE A 1 H51 E57 H95 E110 H53 E59 H97 E112 1.13.11.6 Q1LCS4 RHMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6vi8 A 1.95 BS02 FE2 A 1 C125 C128 C162 C165 C127 C130 C164 C167 1.13.11.6 Q1LCS4 RHMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6vi8 A 1.95 BS03 O A 1 H51 H95 P97 H53 H97 P99 1.13.11.6 Q1LCS4 RHMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6vi8 A 1.95 BS04 O A 2 R47 H51 R49 H53 1.13.11.6 Q1LCS4 RHMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6vi8 A 1.95 BS05 3HA A 1 V41 H51 E57 F59 P97 R99 E110 I142 V43 H53 E59 F61 P99 R101 E112 I144 1.13.11.6 Q1LCS4 RHMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6vi9 A 2.31 BS01 FE2 A 1 C125 C128 C162 C165 C125 C128 C162 C165 1.13.11.6 Q1LCS4 MLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPG 6vi9 A 2.31 BS02 QXM A 1 V41 R47 H51 E57 F59 H95 P97 R99 E110 V41 R47 H51 E57 F59 H95 P97 R99 E110 1.13.11.6 Q1LCS4 MLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPG 6via A 1.59 BS01 FE2 A 1 C125 C128 C162 C165 C127 C130 C164 C167 1.13.11.6 Q1LCS4 RHMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6via A 1.59 BS02 FE A 1 H51 E57 H95 E110 H53 E59 H97 E112 1.13.11.6 Q1LCS4 RHMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6via A 1.59 BS03 EAY A 1 V41 H51 E57 F59 P97 R99 E110 V43 H53 E59 F61 P99 R101 E112 1.13.11.6 Q1LCS4 RHMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6vib A 1.84 BS01 FE2 A 1 H51 E57 H95 E110 H52 E58 H96 E111 1.13.11.6 Q1LCS4 HMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6vib A 1.84 BS02 FE2 A 2 C125 C128 C162 C165 C126 C129 C163 C166 1.13.11.6 Q1LCS4 HMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6vib A 1.84 BS03 2FO A 1 V41 H51 E57 F59 H95 P97 R99 V108 E110 I142 V42 H52 E58 F60 H96 P98 R100 V109 E111 I143 1.13.11.6 Q1LCS4 HMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRAA 6vm0 A 3.14 BS01 PIO A 1 L316 F317 V413 F418 L286 F287 V331 F336 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 A 3.14 BS02 GLY A 1 F87 R89 L141 S153 F57 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 A 3.14 BS03 IVM A 1 T288 S291 S292 S302 V304 D308 A312 L315 T258 S261 S262 S272 V274 D278 A282 L285 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 A 3.14 BS04 IVM E 1 I249 I253 P254 L257 I260 I219 I223 P224 L227 I230 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 A 3.14 BS05 GLY B 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 E 3.14 BS01 GLY A 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 E 3.14 BS02 IVM E 1 T288 S291 S302 D308 A312 L315 T258 S261 S272 D278 A282 L285 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 E 3.14 BS03 PIO E 1 L316 F317 V413 F418 L286 F287 V331 F336 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 E 3.14 BS04 GLY E 1 F87 R89 L141 S153 F57 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 E 3.14 BS05 IVM D 1 I249 I253 P254 L257 I260 I219 I223 P224 L227 I230 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 C 3.14 BS01 PIO C 1 L316 F317 V413 F418 L286 F287 V331 F336 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 C 3.14 BS02 GLY C 1 F87 R89 L141 S153 F57 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 C 3.14 BS03 IVM C 1 T288 S291 S292 S302 V304 D308 A312 L315 T258 S261 S262 S272 V274 D278 A282 L285 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 C 3.14 BS04 IVM B 1 I249 I253 P254 L257 I260 I219 I223 P224 L227 I230 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 C 3.14 BS05 GLY D 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 B 3.14 BS01 IVM A 1 I249 I253 P254 L257 I260 I219 I223 P224 L227 I230 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 B 3.14 BS02 GLY C 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 B 3.14 BS03 GLY B 1 R89 L141 S153 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 B 3.14 BS04 IVM B 1 T288 S291 S302 D308 A312 L315 T258 S261 S272 D278 A282 L285 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 B 3.14 BS05 PIO B 1 L316 F317 V413 F418 L286 F287 V331 F336 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 D 3.14 BS01 GLY E 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 D 3.14 BS02 IVM C 1 I249 I253 P254 L257 I260 I219 I223 P224 L227 I230 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 D 3.14 BS03 IVM D 1 T288 S291 S292 S302 V304 D308 A312 L315 T258 S261 S262 S272 V274 D278 A282 L285 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 D 3.14 BS04 GLY D 1 F87 R89 L141 S153 F57 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm0 D 3.14 BS05 PIO D 1 L316 F317 V413 F418 L286 F287 V331 F336 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 A 3.34 BS01 PIO A 1 L316 F317 V413 F418 L286 F287 V331 F336 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 A 3.34 BS02 GLY A 1 F87 R89 L141 S153 F57 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 A 3.34 BS03 IVM A 1 T288 S291 S292 S302 V304 D308 A312 L315 T258 S261 S262 S272 V274 D278 A282 L285 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 A 3.34 BS04 IVM E 1 I249 I253 P254 L257 I260 I219 I223 P224 L227 I230 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 A 3.34 BS05 GLY B 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 E 3.34 BS01 GLY A 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 E 3.34 BS02 IVM E 1 T288 S291 S302 D308 A312 L315 T258 S261 S272 D278 A282 L285 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 E 3.34 BS03 PIO E 1 L316 F317 V413 F418 L286 F287 V331 F336 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 E 3.34 BS04 GLY E 1 F87 R89 L141 S153 F57 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 E 3.34 BS05 IVM D 1 I249 I253 P254 L257 I260 I219 I223 P224 L227 I230 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 C 3.34 BS01 PIO C 1 L316 F317 V413 F418 L286 F287 V331 F336 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 C 3.34 BS02 GLY C 1 F87 R89 L141 S153 F57 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 C 3.34 BS03 IVM C 1 T288 S291 S292 S302 V304 D308 A312 L315 T258 S261 S262 S272 V274 D278 A282 L285 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 C 3.34 BS04 IVM B 1 I249 I253 P254 L257 I260 I219 I223 P224 L227 I230 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 C 3.34 BS05 GLY D 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 B 3.34 BS01 IVM A 1 I249 I253 P254 L257 I260 I219 I223 P224 L227 I230 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 B 3.34 BS02 GLY C 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 B 3.34 BS03 GLY B 1 R89 L141 S153 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 B 3.34 BS04 IVM B 1 T288 S291 S302 D308 A312 L315 T258 S261 S272 D278 A282 L285 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 B 3.34 BS05 PIO B 1 L316 F317 V413 F418 L286 F287 V331 F336 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 D 3.34 BS01 GLY E 1 F183 Y226 T228 F231 F153 Y196 T198 F201 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 D 3.34 BS02 IVM C 1 I249 I253 P254 L257 I260 I219 I223 P224 L227 I230 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 D 3.34 BS03 IVM D 1 T288 S291 S292 S302 V304 D308 A312 L315 T258 S261 S262 S272 V274 D278 A282 L285 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 D 3.34 BS04 GLY D 1 F87 R89 L141 S153 F57 R59 L111 S123 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm2 D 3.34 BS05 PIO D 1 L316 F317 V413 F418 L286 F287 V331 F336 O93430 PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 A 3.07 BS01 GLY A 1 F87 R89 S153 F56 R58 S122 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 A 3.07 BS02 IVM A 1 T288 S291 R295 V304 A312 L315 T257 S260 R264 V273 A281 L284 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 A 3.07 BS03 IVM E 1 I249 I253 P254 L257 I218 I222 P223 L226 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 A 3.07 BS04 GLY B 1 F183 Y226 T228 F231 F152 Y195 T197 F200 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 E 3.07 BS01 GLY A 1 F183 Y226 T228 F231 F152 Y195 T197 F200 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 E 3.07 BS02 IVM E 1 T288 S291 R295 V304 A312 L315 T257 S260 R264 V273 A281 L284 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 E 3.07 BS03 GLY D 1 F87 R89 S153 F56 R58 S122 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 E 3.07 BS04 IVM D 1 I249 I253 P254 L257 I218 I222 P223 L226 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 C 3.07 BS01 IVM C 1 T288 S291 R295 V304 A312 L315 T257 S260 R264 V273 A281 L284 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 C 3.07 BS02 GLY B 2 F87 R89 S153 F56 R58 S122 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 C 3.07 BS03 IVM B 1 I249 I253 P254 L257 I218 I222 P223 L226 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 C 3.07 BS04 GLY D 2 F183 Y226 T228 F231 F152 Y195 T197 F200 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 B 3.07 BS01 IVM A 1 I249 I253 P254 L257 I218 I222 P223 L226 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 B 3.07 BS02 GLY B 1 R89 L141 S153 R58 L110 S122 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 B 3.07 BS03 GLY B 3 F183 Y226 T228 F231 F152 Y195 T197 F200 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 B 3.07 BS04 IVM B 1 T288 S291 R295 A312 L315 T257 S260 R264 A281 L284 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 D 3.07 BS01 IVM C 1 I249 I253 P254 L257 I218 I222 P223 L226 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 D 3.07 BS02 GLY D 3 R89 L141 S153 R58 L110 S122 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 D 3.07 BS03 GLY D 1 F183 Y226 T228 F231 F152 Y195 T197 F200 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vm3 D 3.07 BS04 IVM D 1 S291 R295 V304 A312 L315 S260 R264 V273 A281 L284 O93430 MPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ 6vmx A 3.10 BS01 III C 1 Y7 R62 N63 I66 Y67 A69 Q70 T73 E76 S77 N80 Y84 L95 Y99 Y116 Y123 T143 K146 W147 Q155 R156 Y159 E163 W167 Y171 Y7 R62 N63 I66 Y67 A69 Q70 T73 E76 S77 N80 Y84 L95 Y99 Y116 Y123 T143 K146 W147 Q155 R156 Y159 E163 W167 Y171 P01889 GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP 6vmx D 3.10 BS01 III C 1 N29 Y37 S109 T111 G112 N30 Y32 S96 T98 G99 MILNVEQSPQSLHVQEGDSTNFTCSFPSSNFYALHWYRWETAKSPEALFVMTLNGDEKKKGRISATLNTKEGYSYLYIKGSQPEDSATYLCAFGSSNTGKLIFGQGTTLQVKPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPS 6vmx E 3.10 BS01 III C 1 Y58 Q108 D109 L110 T112 Y51 Q95 D96 L97 T99 DTEVTQTPKHLVMGMTNKKSLKCEQHMGHRAMYWYKQKAKKPPELMFVYSYEKLSINESVPSRFSPECPNSSLLNLHLHALQPEDSALYLCASSQDLFTGGYTFGSGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 6vmx F 3.10 BS01 III H 1 Y7 R62 N63 I66 Y67 A69 Q70 T73 E76 S77 N80 Y84 L95 Y99 Y116 Y123 T143 W147 Q155 R156 Y159 E163 W167 Y171 Y7 R62 N63 I66 Y67 A69 Q70 T73 E76 S77 N80 Y84 L95 Y99 Y116 Y123 T143 W147 Q155 R156 Y159 E163 W167 Y171 P01889 GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPEEQRYTCHVQHEGLPKP 6vmx I 3.10 BS01 III H 1 N29 Y37 S109 T111 G112 N30 Y32 S96 T98 G99 MILNVEQSPQSLHVQEGDSTNFTCSFPSSNFYALHWYRWETAKSPEALFVMTLNGDEKKKGRISATLNTKEGYSYLYIKGSQPEDSATYLCAFGSSNTGKLIFGQGTTLQVKPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPS 6vmx J 3.10 BS01 III H 1 R37 Y58 Q108 D109 L110 T112 R29 Y50 Q94 D95 L96 T98 TEVTQTPKHLVMGMTNKKSLKCEQHMGHRAMYWYKQKAKKPPELMFVYSYEKLSINESVPSRFSPECPNSSLLNLHLHALQPEDSALYLCASSQDLFTGGYTFGSGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD 6vpc B 3.20 BS01 NUC A 1 K230 L232 E254 A256 T259 R260 K262 R263 R266 R267 R268 Y269 R271 R272 K273 N274 R275 L298 E299 S301 F302 K308 R312 H313 I319 E322 V323 I332 H357 K360 F361 R362 G363 H364 Y522 H525 H526 K533 R537 F548 Y556 A557 I560 D561 Q599 R600 T601 F602 N604 G605 R644 I645 Y647 P651 L652 A653 R654 N656 S657 F659 W661 R664 I670 P672 Y712 R858 K932 L935 Q936 K939 R950 Q1091 T1121 Q1123 K1126 Y1210 K1294 E1296 V1297 G1300 G1301 F1302 I1307 R1319 K1320 K1321 W1323 Y1328 F1331 M1366 H1546 Q1547 S1548 Y1553 K30 L32 E54 A56 T59 R60 K62 R63 R66 R67 R68 Y69 R71 R72 K73 N74 R75 L98 E99 S101 F102 K108 R112 H113 I119 E122 V123 I132 H157 K160 F161 R162 G163 H164 Y322 H325 H326 K333 R337 F348 Y356 A357 I360 D361 Q399 R400 T401 F402 N404 G405 R444 I445 Y447 P451 L452 A453 R454 N456 S457 F459 W461 R464 I470 P472 Y512 R658 K726 L729 Q730 K733 R744 Q879 T892 Q894 K897 Y981 K1065 E1067 V1068 G1071 G1072 F1073 I1078 R1090 K1091 K1092 W1094 Y1099 F1102 M1137 H1317 Q1318 S1319 Y1324 3.1.-.- A0A4U7H5M9 KYSIGLAIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARENQTNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDAIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGTRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQ 6vpc B 3.20 BS02 NUC C 1 Y647 K723 E824 R858 Q892 A925 R975 K979 R1122 Y1210 V1212 K1304 E1305 S1306 K1531 S1535 Y447 K523 E624 R658 Q692 A719 R763 K767 R893 Y981 V983 K1075 E1076 S1077 K1302 S1306 3.1.-.- A0A4U7H5M9 KYSIGLAIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARENQTNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDAIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGTRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQ 6vpc B 3.20 BS03 NUC D 1 K733 L1201 E1204 V1212 Y1213 F1235 A1250 K1304 R1311 S1313 K1315 D1332 S1333 A1412 S1413 Q1418 R1530 R1532 K533 L972 E975 V983 Y984 F1006 A1021 K1075 R1082 S1084 K1086 D1103 S1104 A1183 S1184 Q1189 R1301 R1303 3.1.-.- A0A4U7H5M9 KYSIGLAIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARENQTNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDAIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGTRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQ 6vpc E 3.20 BS01 ZN E 1 H57 C87 C90 H53 C83 C86 EFSHEYWMRHALTLAKRARDEREVPVGAVLVLNNRVIGEGWNRAIGLHDPTAHAEIMALRQGGLVMQNYRLIDATLYVTFEPCVMCAGAMIHSRIGRVVFGVRNSKRGAAGSLMNVLNYPGMNHRVEITEGILADECAALLCDFY 6vpc F 3.20 BS01 NUC D 1 V30 H57 C87 N108 K110 R111 F148 Y149 R153 Q154 F156 N157 V26 H53 C83 N104 K106 R107 F144 Y145 R149 Q150 F152 N153 EFSHEYWMRHALTLAKRARDEREVPVGAVLVLNNRVIGEGWNRAIGLHDPTAHAEIMALRQGGLVMQNYRLIDATLYVTFEPCVMCAGAMIHSRIGRVVFGVRNSKRGAAGSLMNVLNYPGMNHRVEITEGILADECAALLCDFYRMPRQVFNAQK 6vpc F 3.20 BS02 ZN F 1 H57 C87 C90 H53 C83 C86 EFSHEYWMRHALTLAKRARDEREVPVGAVLVLNNRVIGEGWNRAIGLHDPTAHAEIMALRQGGLVMQNYRLIDATLYVTFEPCVMCAGAMIHSRIGRVVFGVRNSKRGAAGSLMNVLNYPGMNHRVEITEGILADECAALLCDFYRMPRQVFNAQK 6vqt A 3.03 BS01 ADP A 1 Y370 R374 S396 G397 G399 K400 S401 Y356 R360 S382 G383 G385 K386 S387 Q2G506 DGWQTLKRFLPYLWPADNAVLRRRVVGAILMVLLGKATTLALPFAYKKAVDAMTLGGGAQPALTVALAFVLAYALGRFSGVLFDNLRNIVFERVGQDATRHLAENVFARLHKLSLRFHLARRTGEVTKVIERGTKSIDTMLYFLLFNIAPTVIELTAVIVIFWLNFGLGLVTATILAVIAYVWTTRTITEWRTHLREKMNRLDGQALARAVDSLLNYETVKYFGAESREEARYASAARAYADAAVKSENSLGLLNIAQALIVNLLMAGAMAWTVYGWSQGKLTVGDLVFVNTYLTQLFRPLDMLGMVYRTIRQGLIDMAEMFRLIDTHIEVADVPNAPALVVNRPSVTFDNVVFGYDRDREILHGLSFEVAAGSRVAIVGPSGAGKSTIARLLFRFYDPWEGRILIDGQDIAHVTQTSLRAALGIVPQDSVLFNDTIGYNIAYGRDGASRAEVDAAAKGAAIADFIARLPQGYDTEVGERGLKLSGGEKQRVAIARTLVKNPPILLFDEATSALDTRTEQDILSTMRAVASHRTTISIAHRLSTIADSDTILVLDQGRLAEQGSHLDLLRRDGLYAEMWARQAA 6vqt A 3.03 BS02 MG A 1 S401 Q442 S387 Q428 Q2G506 DGWQTLKRFLPYLWPADNAVLRRRVVGAILMVLLGKATTLALPFAYKKAVDAMTLGGGAQPALTVALAFVLAYALGRFSGVLFDNLRNIVFERVGQDATRHLAENVFARLHKLSLRFHLARRTGEVTKVIERGTKSIDTMLYFLLFNIAPTVIELTAVIVIFWLNFGLGLVTATILAVIAYVWTTRTITEWRTHLREKMNRLDGQALARAVDSLLNYETVKYFGAESREEARYASAARAYADAAVKSENSLGLLNIAQALIVNLLMAGAMAWTVYGWSQGKLTVGDLVFVNTYLTQLFRPLDMLGMVYRTIRQGLIDMAEMFRLIDTHIEVADVPNAPALVVNRPSVTFDNVVFGYDRDREILHGLSFEVAAGSRVAIVGPSGAGKSTIARLLFRFYDPWEGRILIDGQDIAHVTQTSLRAALGIVPQDSVLFNDTIGYNIAYGRDGASRAEVDAAAKGAAIADFIARLPQGYDTEVGERGLKLSGGEKQRVAIARTLVKNPPILLFDEATSALDTRTEQDILSTMRAVASHRTTISIAHRLSTIADSDTILVLDQGRLAEQGSHLDLLRRDGLYAEMWARQAA 6vqt A 3.03 BS03 ADP B 1 K497 S499 K483 S485 Q2G506 DGWQTLKRFLPYLWPADNAVLRRRVVGAILMVLLGKATTLALPFAYKKAVDAMTLGGGAQPALTVALAFVLAYALGRFSGVLFDNLRNIVFERVGQDATRHLAENVFARLHKLSLRFHLARRTGEVTKVIERGTKSIDTMLYFLLFNIAPTVIELTAVIVIFWLNFGLGLVTATILAVIAYVWTTRTITEWRTHLREKMNRLDGQALARAVDSLLNYETVKYFGAESREEARYASAARAYADAAVKSENSLGLLNIAQALIVNLLMAGAMAWTVYGWSQGKLTVGDLVFVNTYLTQLFRPLDMLGMVYRTIRQGLIDMAEMFRLIDTHIEVADVPNAPALVVNRPSVTFDNVVFGYDRDREILHGLSFEVAAGSRVAIVGPSGAGKSTIARLLFRFYDPWEGRILIDGQDIAHVTQTSLRAALGIVPQDSVLFNDTIGYNIAYGRDGASRAEVDAAAKGAAIADFIARLPQGYDTEVGERGLKLSGGEKQRVAIARTLVKNPPILLFDEATSALDTRTEQDILSTMRAVASHRTTISIAHRLSTIADSDTILVLDQGRLAEQGSHLDLLRRDGLYAEMWARQAA 6vqt B 3.03 BS01 ADP A 1 K497 S499 K483 S485 Q2G506 DGWQTLKRFLPYLWPADNAVLRRRVVGAILMVLLGKATTLALPFAYKKAVDAMTLGGGAQPALTVALAFVLAYALGRFSGVLFDNLRNIVFERVGQDATRHLAENVFARLHKLSLRFHLARRTGEVTKVIERGTKSIDTMLYFLLFNIAPTVIELTAVIVIFWLNFGLGLVTATILAVIAYVWTTRTITEWRTHLREKMNRLDGQALARAVDSLLNYETVKYFGAESREEARYASAARAYADAAVKSENSLGLLNIAQALIVNLLMAGAMAWTVYGWSQGKLTVGDLVFVNTYLTQLFRPLDMLGMVYRTIRQGLIDMAEMFRLIDTHIEVADVPNAPALVVNRPSVTFDNVVFGYDRDREILHGLSFEVAAGSRVAIVGPSGAGKSTIARLLFRFYDPWEGRILIDGQDIAHVTQTSLRAALGIVPQDSVLFNDTIGYNIAYGRDGASRAEVDAAAKGAAIADFIARLPQGYDTEVGERGLKLSGGEKQRVAIARTLVKNPPILLFDEATSALDTRTEQDILSTMRAVASHRTTISIAHRLSTIADSDTILVLDQGRLAEQGSHLDLLRRDGLYAEMWARQAA 6vqt B 3.03 BS02 ADP B 1 Y370 R374 G397 A398 G399 K400 S401 T402 Y356 R360 G383 A384 G385 K386 S387 T388 Q2G506 DGWQTLKRFLPYLWPADNAVLRRRVVGAILMVLLGKATTLALPFAYKKAVDAMTLGGGAQPALTVALAFVLAYALGRFSGVLFDNLRNIVFERVGQDATRHLAENVFARLHKLSLRFHLARRTGEVTKVIERGTKSIDTMLYFLLFNIAPTVIELTAVIVIFWLNFGLGLVTATILAVIAYVWTTRTITEWRTHLREKMNRLDGQALARAVDSLLNYETVKYFGAESREEARYASAARAYADAAVKSENSLGLLNIAQALIVNLLMAGAMAWTVYGWSQGKLTVGDLVFVNTYLTQLFRPLDMLGMVYRTIRQGLIDMAEMFRLIDTHIEVADVPNAPALVVNRPSVTFDNVVFGYDRDREILHGLSFEVAAGSRVAIVGPSGAGKSTIARLLFRFYDPWEGRILIDGQDIAHVTQTSLRAALGIVPQDSVLFNDTIGYNIAYGRDGASRAEVDAAAKGAAIADFIARLPQGYDTEVGERGLKLSGGEKQRVAIARTLVKNPPILLFDEATSALDTRTEQDILSTMRAVASHRTTISIAHRLSTIADSDTILVLDQGRLAEQGSHLDLLRRDGLYAEMWARQAA 6vqt B 3.03 BS03 MG B 1 S401 Q442 S387 Q428 Q2G506 DGWQTLKRFLPYLWPADNAVLRRRVVGAILMVLLGKATTLALPFAYKKAVDAMTLGGGAQPALTVALAFVLAYALGRFSGVLFDNLRNIVFERVGQDATRHLAENVFARLHKLSLRFHLARRTGEVTKVIERGTKSIDTMLYFLLFNIAPTVIELTAVIVIFWLNFGLGLVTATILAVIAYVWTTRTITEWRTHLREKMNRLDGQALARAVDSLLNYETVKYFGAESREEARYASAARAYADAAVKSENSLGLLNIAQALIVNLLMAGAMAWTVYGWSQGKLTVGDLVFVNTYLTQLFRPLDMLGMVYRTIRQGLIDMAEMFRLIDTHIEVADVPNAPALVVNRPSVTFDNVVFGYDRDREILHGLSFEVAAGSRVAIVGPSGAGKSTIARLLFRFYDPWEGRILIDGQDIAHVTQTSLRAALGIVPQDSVLFNDTIGYNIAYGRDGASRAEVDAAAKGAAIADFIARLPQGYDTEVGERGLKLSGGEKQRVAIARTLVKNPPILLFDEATSALDTRTEQDILSTMRAVASHRTTISIAHRLSTIADSDTILVLDQGRLAEQGSHLDLLRRDGLYAEMWARQAA 6vwy A 1.83 BS01 SF4 A 1 C51 N53 C54 M56 G57 C59 G72 V73 C74 I81 R84 M203 C48 N50 C51 M53 G54 C56 G69 V70 C71 I78 R81 M200 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vwy A 1.83 BS02 SF4 A 2 C42 G45 C50 R52 C39 G42 C47 R49 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vwy A 1.83 BS03 XCC A 1 H266 C301 C302 H319 C340 G447 C448 G477 C478 C519 Y553 S554 K556 H263 C298 C299 H316 C337 G444 C445 G474 C475 C516 Y550 S551 K553 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vwy A 1.83 BS04 CUV A 1 H266 C301 C302 H319 C340 G447 C448 G477 C478 C519 Y553 S554 K556 H263 C298 C299 H316 C337 G444 C445 G474 C475 C516 Y550 S551 K553 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vwy B 1.83 BS01 SF4 A 3 C42 G45 C50 R52 C39 G42 C47 R49 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLT 6vwy B 1.83 BS02 SF4 B 1 C51 N53 C54 M56 G57 C59 G72 V73 C74 I81 R84 M203 C48 N50 C51 M53 G54 C56 G69 V70 C71 I78 R81 M200 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLT 6vwy B 1.83 BS03 XCC B 1 H266 C301 C302 H319 C340 G447 C448 G477 C478 C519 Y553 S554 K556 H263 C298 C299 H316 C337 G444 C445 G474 C475 C516 Y550 S551 K553 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLT 6vwy B 1.83 BS04 CUV B 1 H266 C301 C302 H319 C340 G447 C448 G477 C478 C519 Y553 S554 K556 H263 C298 C299 H316 C337 G444 C445 G474 C475 C516 Y550 S551 K553 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLT 6vwz A 2.49 BS01 SF4 A 1 C51 N53 C54 M56 G57 C59 G72 V73 C74 I81 R84 M203 C47 N49 C50 M52 G53 C55 G68 V69 C70 I77 R80 M199 1.2.7.4 Q72A99 32655979 KTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vwz A 2.49 BS02 CUV A 1 H266 C301 C302 H319 C340 G447 C448 G477 C478 C519 Y553 S554 K556 H262 C297 C298 H315 C336 G443 C444 G473 C474 C515 Y549 S550 K552 1.2.7.4 Q72A99 32655979 KTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vwz A 2.49 BS03 SF4 B 1 C42 G45 C50 R52 R60 C38 G41 C46 R48 R56 1.2.7.4 Q72A99 32655979 KTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vwz B 2.49 BS01 SF4 B 1 C42 F44 G45 C50 R52 R60 C39 F41 G42 C47 R49 R57 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vwz B 2.49 BS02 SF4 B 2 C51 N53 C54 M56 G57 C59 G72 V73 C74 I81 R84 M203 C48 N50 C51 M53 G54 C56 G69 V70 C71 I78 R81 M200 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vwz B 2.49 BS03 CUV B 1 H266 C301 C302 H319 C340 G447 C448 G477 C478 C519 Y553 S554 K556 H263 C298 C299 H316 C337 G444 C445 G474 C475 C516 Y550 S551 K553 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vx0 A 2.21 BS01 SF4 A 1 C51 N53 C54 M56 G57 C59 G72 V73 C74 I81 R84 M203 C48 N50 C51 M53 G54 C56 G69 V70 C71 I78 R81 M200 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vx0 A 2.21 BS02 CUV A 1 H266 C301 C302 H319 C340 G447 C448 G477 C478 C519 Y553 S554 K556 H263 C298 C299 H316 C337 G444 C445 G474 C475 C516 Y550 S551 K553 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vx0 B 2.21 BS01 SF4 B 1 C51 N53 C54 M56 G57 C59 G72 V73 C74 I81 R84 M203 C48 N50 C51 M53 G54 C56 G69 V70 C71 I78 R81 M200 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGL 6vx0 B 2.21 BS02 CUV B 1 H266 C301 C302 H319 C340 V446 G447 C448 G477 C478 C519 Y553 S554 K556 H263 C298 C299 H316 C337 V443 G444 C445 G474 C475 C516 Y550 S551 K553 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGL 6vx1 A 2.78 BS01 SF4 A 1 C51 C54 M56 G57 C59 G72 V73 C74 I81 R84 M203 C45 C48 M50 G51 C53 G66 V67 C68 I75 R78 M197 1.2.7.4 Q72A99 32655979 KTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vx1 A 2.78 BS02 CUV A 1 H266 C301 C302 C340 G447 C448 G477 C478 C519 Y553 S554 K556 H260 C295 C296 C334 G441 C442 G471 C472 C513 Y547 S548 K550 1.2.7.4 Q72A99 32655979 KTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vx1 B 2.78 BS01 SF4 B 1 C51 C54 M56 C59 G72 V73 C74 I81 R84 M203 C46 C49 M51 C54 G67 V68 C69 I76 R79 M198 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vx1 B 2.78 BS02 CUV B 1 H266 C301 C302 C340 V446 G447 C448 G477 C478 C519 Y553 S554 K556 H261 C296 C297 C335 V441 G442 C443 G472 C473 C514 Y548 S549 K551 1.2.7.4 Q72A99 32655979 SKTIRSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPKFGELGTCCRNCIMGPCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIETLEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYNDFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDNDHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKDAVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNELLMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFVTTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQPVSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDSANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKAAAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDPVKAADMLEAHIVARRARLGLTS 6vxr A 2.10 BS01 F7D A 1 I17 V25 A38 K40 C70 L86 E87 Y88 C89 P90 G92 L139 I149 I17 V20 A33 K35 C65 L81 E82 Y83 C84 P85 G87 L134 I144 2.7.11.1,2.7.10.2 Q14680 MKDYDELLKYYELHETIAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRL 6w00 L 1.85 BS01 III P 1 Y91 N92 S93 Y94 S95 R95A I96 Y91 N92 S93 Y94 S95 R96 I97 DIQMTQSPSTLSASVGDRVTITCRASQSVSTSLAWYQQKPGKAPNLLIYQASTLYRGVPSRFSGSGSGTEFTLTIGSLQPDDFATYYCQHYNSYSRITFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 6w00 H 1.85 BS01 III P 1 N31 F32 G33 W52 H52A F58 D95 G97 G98 A99 R100B N31 F32 G33 W52 H53 F59 D99 G101 G102 A103 R106 QVQLVESGGGVVQPGRSLRLSCAASRLTFRNFGMHWVRQTPGKGLEWVAVIWHDGSNKFYADSVEGRFTISRDNSKNTLYLQMNSLRDEDTAIYYCAKDWGGASDRVFDYWGRGTLVIVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC 6w05 H 2.52 BS01 III P 1 N31 F32 G33 W52 H52A F58 D95 S96 Y99 D100 H100A S100D N30 F31 G32 W51 H52 F58 D98 S99 Y102 D103 H104 S107 VQLVESGGGVVQPGRSLRLSCAASGFTFRNFGMHWVRQTPGKGLEWVAVIWHDGSNKFYADSVEGRFTISRDNSKNMIYLQMNSLRVEDTAIYYCARDSLFYDHDNSGYYGYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 6w05 L 2.52 BS01 III P 1 Y91 N92 N93 G94 F96 Y91 N92 N93 G94 F95 QIVMTQSPATVSVSPGERATLSCRASRSVTSKLAWYQQKPGQAPRLLIYGASTRATGIPARFSGSGSGTEFTLTISSLQSEDFAVYFCQQYNNGFTFGPGTKVDFKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6w1i A 1.80 BS01 G4P A 1 V19 L20 K21 V22 N27 E58 S59 S60 K81 S98 T100 D125 F126 A128 N129 K156 V22 L23 K24 V25 N30 E61 S62 S63 K84 S101 T103 D128 F129 A131 N132 K159 2.4.2.22 P42085 32446804 SNAMEALKRKIEEEGVVLSDQVLKVDSFLNHQIDPLLMQRIGDEFASRFAKDGITKIVTIESSGIAPAVMTGLKLGVPVVFARKHKSLTLTDNLLTASVYSFTKQTESQIAVSGTHLSDQDHVLIIDDFLANGQAAHGLVSIVKQAGASIAGIGIVIEKSFQPGRDELVKLGYRVESLARIQSLEEGKVSFVQ 6w1i A 1.80 BS02 G4P B 1 R80 L85 T86 R83 L88 T89 2.4.2.22 P42085 32446804 SNAMEALKRKIEEEGVVLSDQVLKVDSFLNHQIDPLLMQRIGDEFASRFAKDGITKIVTIESSGIAPAVMTGLKLGVPVVFARKHKSLTLTDNLLTASVYSFTKQTESQIAVSGTHLSDQDHVLIIDDFLANGQAAHGLVSIVKQAGASIAGIGIVIEKSFQPGRDELVKLGYRVESLARIQSLEEGKVSFVQ 6w1i B 1.80 BS01 G4P A 1 R80 L85 T86 R82 L87 T88 2.4.2.22 P42085 32446804 NAMEALKRKIEEEGVVLSDQVLKVDSFLNHQIDPLLMQRIGDEFASRFAKDGITKIVTIESSGIAPAVMTGLKLGVPVVFARKHKSLTLTDNLLTASVYSFTKQTESQIAVSGTHLSDQDHVLIIDDFLANGQAAHGLVSIVKQAGASIAGIGIVIEKSFQPGRDELVKLGYRVESLARIQSLEEGKVSFVQEV 6w1i B 1.80 BS02 G4P B 1 Q18 V19 L20 K21 V22 N27 E58 S59 S60 K81 S98 D125 F126 A128 N129 K156 Q20 V21 L22 K23 V24 N29 E60 S61 S62 K83 S100 D127 F128 A130 N131 K158 2.4.2.22 P42085 32446804 NAMEALKRKIEEEGVVLSDQVLKVDSFLNHQIDPLLMQRIGDEFASRFAKDGITKIVTIESSGIAPAVMTGLKLGVPVVFARKHKSLTLTDNLLTASVYSFTKQTESQIAVSGTHLSDQDHVLIIDDFLANGQAAHGLVSIVKQAGASIAGIGIVIEKSFQPGRDELVKLGYRVESLARIQSLEEGKVSFVQEV 6w1i C 1.80 BS01 G4P C 1 V19 L20 K21 V22 N27 E58 S59 S60 K81 S98 F99 T100 D125 F126 A128 N129 K156 V21 L22 K23 V24 N29 E60 S61 S62 K83 S100 F101 T102 D127 F128 A130 N131 K158 2.4.2.22 P42085 32446804 NAMEALKRKIEEEGVVLSDQVLKVDSFLNHQIDPLLMQRIGDEFASRFAKDGITKIVTIESSGIAPAVMTGLKLGVPVVFARKHKSLTLTDNLLTASVYSFTKQTESQIAVSGTHLSDQDHVLIIDDFLANGQAAHGLVSIVKQAGASIAGIGIVIEKSFQPGRDELVKLGYRVESLARIQSLEEGKVSFVQ 6w1i C 1.80 BS02 G4P D 1 R80 L85 T86 R82 L87 T88 2.4.2.22 P42085 32446804 NAMEALKRKIEEEGVVLSDQVLKVDSFLNHQIDPLLMQRIGDEFASRFAKDGITKIVTIESSGIAPAVMTGLKLGVPVVFARKHKSLTLTDNLLTASVYSFTKQTESQIAVSGTHLSDQDHVLIIDDFLANGQAAHGLVSIVKQAGASIAGIGIVIEKSFQPGRDELVKLGYRVESLARIQSLEEGKVSFVQ 6w1i D 1.80 BS01 G4P C 1 R80 L85 T86 R83 L88 T89 2.4.2.22 P42085 32446804 SNAMEALKRKIEEEGVVLSDQVLKVDSFLNHQIDPLLMQRIGDEFASRFAKDGITKIVTIESSGIAPAVMTGLKLGVPVVFARKHKSLTLTDNLLTASVYSFTKQTESQIAVSGTHLSDQDHVLIIDDFLANGQAAHGLVSIVKQAGASIAGIGIVIEKSFQPGRDELVKLGYRVESLARIQSLEEGKVSFVQE 6w1i D 1.80 BS02 G4P D 1 Q18 V19 L20 K21 V22 N27 E58 S59 S60 K81 S98 F99 T100 D125 F126 A128 N129 K156 Q21 V22 L23 K24 V25 N30 E61 S62 S63 K84 S101 F102 T103 D128 F129 A131 N132 K159 2.4.2.22 P42085 32446804 SNAMEALKRKIEEEGVVLSDQVLKVDSFLNHQIDPLLMQRIGDEFASRFAKDGITKIVTIESSGIAPAVMTGLKLGVPVVFARKHKSLTLTDNLLTASVYSFTKQTESQIAVSGTHLSDQDHVLIIDDFLANGQAAHGLVSIVKQAGASIAGIGIVIEKSFQPGRDELVKLGYRVESLARIQSLEEGKVSFVQE 6wfw H 2.09 BS01 III P 1 G31 Y32 G33 I50 W52 F52A Y58 V95 H96 P100 G30 Y31 G32 I49 W51 F52 Y58 V97 H98 P102 QVQLVESGGGVVQPGSLRLSCAASGFTFSGYGMHWVRQVPGKGLEWVAIIWFDGSQKYYADSVQGRFTISRDNKKTLFLRMNSLRAEDTAVYYCAKVHDDEPTQDYWGQGTLVTVFNQIKGPSVFPLAPSSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 6wfw L 2.09 BS01 III P 1 Y91 K92 R93 Y94 W96 Y90 K91 R92 Y93 W94 IQMTQSPSTLSASVGDRVTITCRASQGISTSLAWYQQKPGKAPKLLIYKASSLESGVPSRFSGSGSGTEFTLTITSLQPEDFATYYCQQYKRYWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6wfx H 2.59 BS01 III P 1 C32 Y33 G34 W52 H52A A95 Y98 D99 I100 L100A T100B C31 Y32 G33 W52 H53 A99 Y102 D103 I104 L105 T106 EQLVESGGGVVQPGRSLRLSCAAASEFCFSCYGMHWVRQAPGKGLEWVAVIWHDGSNQHFADSVKGRFTISRDNSKNIMYLQMNSLRAEDTAVYYCASATRYDILTGAFDYWGQGTLVTVVSRRLPPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC 6wfy H 1.23 BS01 III P 1 A33 F50 R52 Y53 H58 Q96 L97 Y100C Q100D Y100E Y100F A33 F50 R52 Y56 H61 Q102 L103 Y109 Q110 Y111 Y112 EVQLVESGGGLVQPGRSLRLPCTASGFSFGDHAMSWVRQAPGKGLEWVGFIRKTTYGATTHYAAAVRGRFTISRDDSKSIVYLQMNSLKTEDTAVYFCTRVQLDYGPGYQYYGMDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 6wfy L 1.23 BS01 III P 1 A29 G30 Y31 D32 Y91 N95A W96 A31 G32 Y33 D34 Y93 N98 W100 ESVLTQPPSVSGAPGQRVTISCTGMNSNIGAGYDVYWYQQLPGRAPKLLIYGNSNRPSGVPDRFSGSRSGTSASLAITGLQAEDEADYYCQSYDTSLNGWAFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLVSDFYPGAVTVAWKADGSPVKVGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCRVTHEGSTVEKTVAPAE 6wfz A 1.84 BS01 III C 1 F50 R52 F53 E58 V95 G96 V97 A100 F50 R52 F56 E61 V101 G102 V103 A106 EVQLVESGGGLVQPGRSLRLSCTTSGFTFGDYAMSWFRQAPGKGLEWVGFIRSKGFGGTAEYAAFVKGRFTISRDDSRSIAYLQMTSLKPEDTAVYYCSRVGVVIATAVYWGQGTLVTVSSASTKGPSVFPLAPSSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP 6wfz B 1.84 BS01 III C 1 R91 I92 D93 L94 W96 R96 I97 D98 L99 W101 DILMTQTPLSLSVTPGQPASISCKSSQSLLDNDGKTYLYWYLQKPGQSPQLLIYEVSNRFSGVPERFSGSGSGTDFTLKIRRVEAEDVGVYYCMQRIDLPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 6wfz H 1.84 BS01 III P 1 A33 F50 R52 F53 E58 V95 G96 V97 A100 A33 F50 R52 F56 E61 V101 G102 V103 A106 EVQLVESGGGLVQPGRSLRLSCTTSGFTFGDYAMSWFRQAPGKGLEWVGFIRSKGFGGTAEYAAFVKGRFTISRDDSRSIAYLQMTSLKPEDTAVYYCSRVGVVIATAVYWGQGTLVTVSSASTKGPSVFPLAPGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP 6wfz L 1.84 BS01 III P 1 R91 I92 D93 L94 W96 R96 I97 D98 L99 W101 DILMTQTPLSLSVTPGQPASISCKSSQSLLDNDGKTYLYWYLQKPGQSPQLLIYEVSNRFSGVPERFSGSGSGTDFTLKIRRVEAEDVGVYYCMQRIDLPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6wg0 H 1.60 BS01 III P 1 T30 D31 F32 Y33 N52 H53 D96 Q97 E98 T30 D31 F32 Y33 N52 H54 D100 Q101 E102 QVQLVQSGAEVKKPGASARVSCKASGYTLTDFYLHWVRQAPGQGLEWMGWLNPHSGGTNYAQKFLGRVSMTRDTSISTAYMELNKLISDDTAVYFCVRSDQEALRGAFDIWGQGTMVFVVSRRLPPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC 6wg0 L 1.60 BS01 III P 1 S28 N30 Y32 S91 H92 L94 W96 S28 N30 Y32 S91 H92 L94 W95 DIQMTQSPSSLSASVGDTVTITCRASQSINDYLNWYQQKPGKAPKLLIYATSSLHSGVPSRFSGSGFGTDFTLTISSLQPEDSATYLCQQSHSLWTFGQGTKVEVKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 6wg1 A 2.09 BS01 III C 1 F50 R52 F53 E58 V95 G96 V97 A100 F50 R52 F56 E61 V101 G102 V103 A106 EVQLVESGGGLVQPGRSLRLSCTTSGFTFGDYAMSWFRQAPGKGLEWVGFIRSKGFGGTAEYAAFVKGRFTISRDDSRSIAYLQMTSLKPEDTAVYYCSRVGVVIATAVYWGQGTLVTVSSASTKGPSVFPLAPGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK 6wg1 B 2.09 BS01 III C 1 R91 D93 L94 W96 R96 D98 L99 W101 DILMTQTPLSLSVTPGQPASISCKSSQSLLDNDGKTYLYWYLQKPGQSPQLLIYEVSNRFSGVPERFSGSGSGTDFTLKIRRVEAEDVGVYYCMQRIDLPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6wg1 H 2.09 BS01 III C 1 F50 R52 F53 E58 V95 G96 V97 A100 F50 R52 F56 E61 V101 G102 V103 A106 EVQLVESGGGLVQPGRSLRLSCTTSGFTFGDYAMSWFRQAPGKGLEWVGFIRSKGFGGTAEYAAFVKGRFTISRDDSRSIAYLQMTSLKPEDTAVYYCSRVGVVIATAVYWGQGTLVTVSSASTKGPSVFPLAPGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP 6wg1 L 2.09 BS01 III C 1 D27D N27E D28 R91 I92 D93 L94 W96 D31 N32 D33 R96 I97 D98 L99 W101 DILMTQTPLSLSVTPGQPASISCKSSQSLLDNDGKTYLYWYLQKPGQSPQLLIYEVSNRFSGVPERFSGSGSGTDFTLKIRRVEAEDVGVYYCMQRIDLPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 6wg2 H 2.53 BS01 III P 1 N31 F32 G33 W52 H52A F58 D95 G97 A99 R100B N31 F32 G33 W52 H53 F59 D99 G101 A103 R106 QVQLVESGGGVVQPGRSLRLSCAASRLTFRNFGMHWVRQTPGKGLEWVAVIWHDGSNKFYADSVEGRFTISRDNSKNTLYLQMNSLRDEDTAIYYCAKDWGGASDRVFDYWGRGTLVIVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 6wg2 I 2.53 BS01 III P 1 N31 F32 G33 W52 H52A F58 D95 G97 A99 R100B N30 F31 G32 W51 H52 F58 D98 G100 A102 R105 VQLVESGGGVVQPGRSLRLSCAASRLTFRNFGMHWVRQTPGKGLEWVAVIWHDGSNKFYADSVEGRFTISRDNSKNTLYLQMNSLRDEDTAIYYCAKDWGGASDRVFDYWGRGTLVIVSSASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS 6wg2 L 2.53 BS01 III P 1 Y91 N92 S93 Y94 S95 I96 Y91 N92 S93 Y94 S95 I97 DIQMTQSPSTLSASVGDRVTITCRASQSVSTSLAWYQQKPGKAPNLLIYQASTLYRGVPSRFSGSGSGTEFTLTIGSLQPDDFATYYCQHYNSYSRITFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6wg2 M 2.53 BS01 III P 1 Y91 N92 S93 Y94 S95 I96 Y91 N92 S93 Y94 S95 I97 DIQMTQSPSTLSASVGDRVTITCRASQSVSTSLAWYQQKPGKAPNLLIYQASTLYRGVPSRFSGSGSGTEFTLTIGSLQPDDFATYYCQHYNSYSRITFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 6wii A 1.85 BS01 U2V A 1 A45 W46 N79 R80 F82 L83 C119 D122 Y125 Q138 F141 I152 A153 M156 R157 M172 H195 A44 W45 N78 R79 F81 L82 C118 D121 Y124 Q137 F140 I151 A152 M155 R156 M161 H184 3.6.1.54 A0A1S0WIC1 32663666 ATLFIADLHLQTEEPAITAGFLRFLQGEARQADALYILGDLFEAWIGDDDPNPLHQQIASAIKAVVDAGVPCYFIHGNRDFLVGQRFARQSGMILLAEEERLDLYGREVLIMHGDTLCTDDQGYLAFRAKVHTPWIQRLFLALPLFIRHRIAARMRADEIMDVNPQAVVDAMERHHVQWLIHGHTHRPAVHELQANGQPAWRVVLGAWHSEGSMVKVTPDDVELIHFPFLEENLYFQS 6wii A 1.85 BS02 MN A 1 D8 H10 D41 H197 D7 H9 D40 H186 3.6.1.54 A0A1S0WIC1 32663666 ATLFIADLHLQTEEPAITAGFLRFLQGEARQADALYILGDLFEAWIGDDDPNPLHQQIASAIKAVVDAGVPCYFIHGNRDFLVGQRFARQSGMILLAEEERLDLYGREVLIMHGDTLCTDDQGYLAFRAKVHTPWIQRLFLALPLFIRHRIAARMRADEIMDVNPQAVVDAMERHHVQWLIHGHTHRPAVHELQANGQPAWRVVLGAWHSEGSMVKVTPDDVELIHFPFLEENLYFQS 6wii A 1.85 BS03 MN A 2 D8 D41 N79 H114 H195 D7 D40 N78 H113 H184 3.6.1.54 A0A1S0WIC1 32663666 ATLFIADLHLQTEEPAITAGFLRFLQGEARQADALYILGDLFEAWIGDDDPNPLHQQIASAIKAVVDAGVPCYFIHGNRDFLVGQRFARQSGMILLAEEERLDLYGREVLIMHGDTLCTDDQGYLAFRAKVHTPWIQRLFLALPLFIRHRIAARMRADEIMDVNPQAVVDAMERHHVQWLIHGHTHRPAVHELQANGQPAWRVVLGAWHSEGSMVKVTPDDVELIHFPFLEENLYFQS 6wn4 A 2.80 BS01 III C 1 I52 H54 W69 Y71 N76 K78 H118 E119 D120 R121 N122 Y123 I33 H35 W50 Y52 N57 K59 H99 E100 D101 R102 N103 Y104 KVQLQQSGAELVKPGASVKLSCKASGYTFTEYIIHWVKQKSGQGLEWIGWFYPGSGNIKYNEKFKDKATLTADKSSSTVYMELSRLTSEDSAVYFCARHEDRNYYSYWDYWGQGTTLTVSSAKTTPPSVYPLAPNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVP 6wn4 B 2.80 BS01 III C 1 W112 N115 W90 N93 QIVLTQSPALMSASPGEKVTMTCSASSSVSNMYWYQQKPRSSPKPWIYLTSNLASGVPARFSGSGSGTSYSLTISSMEAEDAATYYCQQWSSNPLTFGAGTKLELKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHSTSPIVKSFNR 6wn4 H 2.80 BS01 III D 1 I52 H54 W69 Y71 N76 K78 H118 E119 D120 R121 N122 Y123 I33 H35 W50 Y52 N57 K59 H99 E100 D101 R102 N103 Y104 KVQLQQSGAELVKPGASVKLSCKASGYTFTEYIIHWVKQKSGQGLEWIGWFYPGSGNIKYNEKFKDKATLTADKSSSTVYMELSRLTSEDSAVYFCARHEDRNYYSYWDYWGQGTTLTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPR 6wn4 L 2.80 BS01 III D 1 W112 N115 W90 N93 QIVLTQSPALMSASPGEKVTMTCSASSSVSNMYWYQQKPRSSPKPWIYLTSNLASGVPARFSGSGSGTSYSLTISSMEAEDAATYYCQQWSSNPLTFGAGTKLELKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 6wp8 A 2.50 BS01 RET A 1 F72 W75 T79 M107 Y126 S129 C130 Y133 W170 Y173 P174 W177 D200 S203 K204 F72 W75 T79 M107 Y126 S129 C130 Y133 W170 Y173 P174 W177 D200 S203 K204 MTQAWLWIGVISMALGSVFFGFGAHNAKNERWQILYTLNFFICLIAAGLYLAMALGLGVNVINGRPTYWVRFVDWFCSTPLLLLDLTFLGRTSLPLTGSLLGANAYMLVTGFVATVTPKPMSYIWYIVSCAAYLAIVYLLAQPYRIAAERKHPRSKQAFRTLVTVHLVLWTLYPIVWILSPEGFSTFTQGSETMFYTLLDIASKVGFGFLSLNTLHTLEQAT 6wq2 A 4.00 BS01 NUC 1 1 R3 R15 Y16 E53 W57 D60 A90 E93 K94 N98 R1 R13 Y14 E51 W55 D58 A88 E91 K92 N96 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 A 4.00 BS02 NUC 2 1 N5 R6 R7 L8 S12 R15 Y16 K19 R20 W57 Y61 H65 K68 K72 G82 A83 M89 K104 N3 R4 R5 L6 S10 R13 Y14 K17 R18 W55 Y59 H63 K66 K70 G80 A81 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 B 4.00 BS01 NUC 1 1 R3 R15 Y16 K19 R20 E53 W57 D60 A90 E93 R1 R13 Y14 K17 R18 E51 W55 D58 A88 E91 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 B 4.00 BS02 NUC 2 1 N5 R6 L8 S12 R15 Y16 K19 R20 W57 Y61 H65 K68 K72 G82 A83 G86 M89 K104 N3 R4 L6 S10 R13 Y14 K17 R18 W55 Y59 H63 K66 K70 G80 A81 G84 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 C 4.00 BS01 NUC 1 1 R3 R15 Y16 R20 E53 N56 W57 D60 A90 E93 K94 R1 R13 Y14 R18 E51 N54 W55 D58 A88 E91 K92 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 C 4.00 BS02 NUC 2 1 N5 R6 R7 L8 S12 R15 Y16 K19 R20 W57 Y61 H65 K68 G82 M89 K104 N3 R4 R5 L6 S10 R13 Y14 K17 R18 W55 Y59 H63 K66 G80 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 D 4.00 BS01 NUC 1 1 A11 R15 Y16 E53 W57 D60 A90 E93 K94 A9 R13 Y14 E51 W55 D58 A88 E91 K92 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 D 4.00 BS02 NUC 2 1 R6 R7 L8 S12 R15 Y16 K19 R20 W57 Y61 K68 Q85 G86 M89 K104 R4 R5 L6 S10 R13 Y14 K17 R18 W55 Y59 K66 Q83 G84 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 E 4.00 BS01 NUC 1 1 R3 R15 Y16 K19 R20 E53 N56 W57 D60 A90 E93 K94 N98 R1 R13 Y14 K17 R18 E51 N54 W55 D58 A88 E91 K92 N96 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 E 4.00 BS02 NUC 2 1 N5 R6 R7 L8 S12 R15 Y16 K19 R20 W57 Y61 H65 K68 K72 G82 G86 M89 K104 N3 R4 R5 L6 S10 R13 Y14 K17 R18 W55 Y59 H63 K66 K70 G80 G84 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 F 4.00 BS01 NUC 1 1 R3 R15 Y16 E53 W57 D60 A90 E93 K94 R1 R13 Y14 E51 W55 D58 A88 E91 K92 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 F 4.00 BS02 NUC 2 1 N5 R6 R7 L8 S12 R15 Y16 K19 W57 Y61 H65 K68 G82 A83 G86 M89 K104 N3 R4 R5 L6 S10 R13 Y14 K17 W55 Y59 H63 K66 G80 A81 G84 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 G 4.00 BS01 NUC 1 1 R3 R15 Y16 R20 E53 W57 D60 A90 E93 K94 R1 R13 Y14 R18 E51 W55 D58 A88 E91 K92 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 G 4.00 BS02 NUC 2 1 N5 R6 R7 L8 S12 R15 K19 R20 W57 Y61 H65 K68 K72 G82 A83 M89 K104 N3 R4 R5 L6 S10 R13 K17 R18 W55 Y59 H63 K66 K70 G80 A81 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 H 4.00 BS01 NUC 1 1 R3 R15 Y16 K19 R20 E53 N56 W57 D60 A90 E93 K94 N98 R1 R13 Y14 K17 R18 E51 N54 W55 D58 A88 E91 K92 N96 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 H 4.00 BS02 NUC 2 1 N5 R7 L8 S12 R15 Y16 K19 R20 W57 Y61 H65 K68 G82 A83 G86 M89 K104 N3 R5 L6 S10 R13 Y14 K17 R18 W55 Y59 H63 K66 G80 A81 G84 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 I 4.00 BS01 NUC 1 1 R3 R15 Y16 E53 W57 D60 A90 E93 K94 R1 R13 Y14 E51 W55 D58 A88 E91 K92 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 I 4.00 BS02 NUC 2 1 N5 R6 R7 L8 S12 R15 Y16 K19 W57 Y61 H65 K68 K72 G82 A83 G86 M89 K104 N3 R4 R5 L6 S10 R13 Y14 K17 W55 Y59 H63 K66 K70 G80 A81 G84 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 J 4.00 BS01 NUC 1 1 R3 R15 Y16 K19 R20 T27 E53 N56 W57 D60 Y61 A90 E93 K94 A97 R1 R13 Y14 K17 R18 T25 E51 N54 W55 D58 Y59 A88 E91 K92 A95 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 J 4.00 BS02 NUC 2 1 N5 R6 R7 L8 S12 R15 K19 R20 W57 Y61 H65 K68 K72 G82 A83 M89 K104 N3 R4 R5 L6 S10 R13 K17 R18 W55 Y59 H63 K66 K70 G80 A81 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 K 4.00 BS01 NUC 1 1 R3 R15 Y16 K19 E53 W57 D60 A90 E93 R1 R13 Y14 K17 E51 W55 D58 A88 E91 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 K 4.00 BS02 NUC 2 1 N5 R6 R7 L8 S12 R15 Y16 K19 R20 W57 Y61 H65 K68 K72 G82 M89 K104 N3 R4 R5 L6 S10 R13 Y14 K17 R18 W55 Y59 H63 K66 K70 G80 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 L 4.00 BS01 NUC 1 1 R3 R15 Y16 K19 R20 E53 N56 W57 D60 A90 E93 R1 R13 Y14 K17 R18 E51 N54 W55 D58 A88 E91 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 L 4.00 BS02 NUC 2 1 N5 R6 R7 L8 S12 R15 Y16 K19 R20 W57 Y61 H65 K68 K72 G82 M89 K104 N3 R4 R5 L6 S10 R13 Y14 K17 R18 W55 Y59 H63 K66 K70 G80 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 M 4.00 BS01 NUC 1 1 R15 Y16 K19 R20 E53 N56 W57 D60 A90 E93 K94 R13 Y14 K17 R18 E51 N54 W55 D58 A88 E91 K92 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 M 4.00 BS02 NUC 2 1 R6 R7 L8 S12 R15 Y16 K19 R20 W57 Y61 K68 G82 G86 M89 K104 R4 R5 L6 S10 R13 Y14 K17 R18 W55 Y59 K66 G80 G84 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 N 4.00 BS01 NUC 1 1 R3 R15 Y16 E53 N56 W57 D60 A90 E93 K94 R1 R13 Y14 E51 N54 W55 D58 A88 E91 K92 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 N 4.00 BS02 NUC 2 1 N5 R6 R7 L8 S12 R15 Y16 K19 R20 W57 Y61 H65 K68 G82 M89 K104 N3 R4 R5 L6 S10 R13 Y14 K17 R18 W55 Y59 H63 K66 G80 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 P 4.00 BS01 NUC 1 1 R3 R15 Y16 K19 R20 E53 W57 D60 A90 E93 K94 R1 R13 Y14 K17 R18 E51 W55 D58 A88 E91 K92 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 P 4.00 BS02 NUC 2 1 N5 R6 R7 L8 S12 R15 Y16 K19 W57 Y61 H65 K68 K72 G82 A83 M89 K104 N3 R4 R5 L6 S10 R13 Y14 K17 W55 Y59 H63 K66 K70 G80 A81 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 R 4.00 BS01 NUC 1 1 R3 R15 Y16 R20 E53 N56 W57 D60 A90 E93 K94 R1 R13 Y14 R18 E51 N54 W55 D58 A88 E91 K92 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 R 4.00 BS02 NUC 2 1 N5 R6 L8 S12 R15 Y16 K19 R20 W57 Y61 H65 K68 G82 M89 K104 N3 R4 L6 S10 R13 Y14 K17 R18 W55 Y59 H63 K66 G80 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 T 4.00 BS01 NUC 1 1 R3 R15 Y16 E53 W57 D60 A90 E93 R1 R13 Y14 E51 W55 D58 A88 E91 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 T 4.00 BS02 NUC 2 1 N5 R6 R7 L8 S12 R15 K19 W57 Y61 H65 K68 K72 G82 G86 M89 K104 N3 R4 R5 L6 S10 R13 K17 W55 Y59 H63 K66 K70 G80 G84 M87 K102 Q914J5 RRNRRLSSASVYRYYLKRISMNIGTTGHVNGLSIAGNPEIMRAIARLSEQETYNWVTDYAPSHLAKEVVKQISGKYNIPGAYQGLLMAFAEKVLANYILDYKGEPLVEIHHNFLWELMQGFIYTFVRKDGKPVTVDMSKVLTEIEDALFKLVKK 6wq2 a 4.00 BS01 NUC 1 1 R4 I10 D11 V12 T16 R19 Y20 L24 I27 Y48 H60 R64 G74 F77 W80 N163 Y181 R2 I8 D9 V10 T14 R17 Y18 L22 I25 Y46 H58 R62 G72 F75 W78 N161 Y179 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 a 4.00 BS02 NUC 2 1 R13 D15 R19 K23 M44 N47 Y48 F52 Y56 F77 Q81 N84 E85 Y88 T186 R11 D13 R17 K21 M42 N45 Y46 F50 Y54 F75 Q79 N82 E83 Y86 T184 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 b 4.00 BS01 NUC 1 1 I10 D11 V12 R13 T16 R19 Y20 I27 Y48 F52 N57 H60 R64 G74 F77 W80 P162 N163 S164 Y181 I8 D9 V10 R11 T14 R17 Y18 I25 Y46 F50 N55 H58 R62 G72 F75 W78 P160 N161 S162 Y179 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 b 4.00 BS02 NUC 2 1 Q5 R13 D15 R19 Y20 K23 Y31 M44 N47 Y48 F52 Y56 F77 Q81 N84 E85 Y88 R108 T186 Q3 R11 D13 R17 Y18 K21 Y29 M42 N45 Y46 F50 Y54 F75 Q79 N82 E83 Y86 R106 T184 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 c 4.00 BS01 NUC 1 1 I10 D11 V12 R13 T16 R19 Y20 I27 Y48 N57 H60 R64 G74 F77 W80 K95 N163 S164 Y181 I8 D9 V10 R11 T14 R17 Y18 I25 Y46 N55 H58 R62 G72 F75 W78 K93 N161 S162 Y179 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 c 4.00 BS02 NUC 2 1 Q5 R13 D15 R19 Y20 K23 M44 N47 Y48 V51 F52 Y56 F77 Q81 N84 E85 Y88 G183 T186 Q3 R11 D13 R17 Y18 K21 M42 N45 Y46 V49 F50 Y54 F75 Q79 N82 E83 Y86 G181 T184 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 d 4.00 BS01 NUC 1 1 R4 I10 D11 V12 R13 T16 R19 Y20 L24 I27 Y48 N57 H60 R64 G74 F77 W80 N163 S164 Y181 R2 I8 D9 V10 R11 T14 R17 Y18 L22 I25 Y46 N55 H58 R62 G72 F75 W78 N161 S162 Y179 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 d 4.00 BS02 NUC 2 1 Q5 R13 D15 Y20 K23 M44 N47 Y48 F52 Y56 F77 Q81 N84 E85 Y88 T186 Q3 R11 D13 Y18 K21 M42 N45 Y46 F50 Y54 F75 Q79 N82 E83 Y86 T184 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 e 4.00 BS01 NUC 1 1 R4 I10 D11 V12 R13 T16 R19 Y20 I27 Y48 N57 H60 R64 G74 F77 W80 K95 N163 Y181 R2 I8 D9 V10 R11 T14 R17 Y18 I25 Y46 N55 H58 R62 G72 F75 W78 K93 N161 Y179 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 e 4.00 BS02 NUC 2 1 Q5 S6 R13 D15 R19 Y20 K23 M44 Y48 F52 Y56 F77 Q81 N84 E85 Y88 G183 T186 Q3 S4 R11 D13 R17 Y18 K21 M42 Y46 F50 Y54 F75 Q79 N82 E83 Y86 G181 T184 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 f 4.00 BS01 NUC 1 1 I10 D11 V12 T16 R19 Y20 L24 I27 Y48 N57 H60 R64 G74 F77 W80 K95 N163 I8 D9 V10 T14 R17 Y18 L22 I25 Y46 N55 H58 R62 G72 F75 W78 K93 N161 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 f 4.00 BS02 NUC 2 1 Q5 R13 D15 R19 Y20 K23 M44 N47 Y48 F52 Y56 F77 Q81 N84 E85 Y88 Q3 R11 D13 R17 Y18 K21 M42 N45 Y46 F50 Y54 F75 Q79 N82 E83 Y86 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 g 4.00 BS01 NUC 1 1 R4 I10 D11 V12 R13 T16 R19 Y20 L24 I27 Y48 N57 H60 R64 G74 F77 W80 K95 P162 N163 S164 Y181 R2 I8 D9 V10 R11 T14 R17 Y18 L22 I25 Y46 N55 H58 R62 G72 F75 W78 K93 P160 N161 S162 Y179 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 g 4.00 BS02 NUC 2 1 Q5 R13 D15 R19 Y20 K23 M44 N47 Y48 F52 Y56 F77 Q81 N84 E85 Y88 G183 T186 Q3 R11 D13 R17 Y18 K21 M42 N45 Y46 F50 Y54 F75 Q79 N82 E83 Y86 G181 T184 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 h 4.00 BS01 NUC 1 1 G3 R4 I10 D11 V12 T16 R19 Y20 I27 Y48 H60 R64 G74 F77 W80 K95 N163 S164 G1 R2 I8 D9 V10 T14 R17 Y18 I25 Y46 H58 R62 G72 F75 W78 K93 N161 S162 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 h 4.00 BS02 NUC 2 1 Q5 S6 R13 D15 R19 Y20 K23 M44 N47 Y48 F52 Y56 F77 Q81 N84 E85 Y88 Q3 S4 R11 D13 R17 Y18 K21 M42 N45 Y46 F50 Y54 F75 Q79 N82 E83 Y86 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 i 4.00 BS01 NUC 1 1 R4 I10 D11 V12 R13 T16 R19 Y20 K23 L24 I27 Y48 N57 H60 R64 G74 F77 W80 K95 N163 Y181 R2 I8 D9 V10 R11 T14 R17 Y18 K21 L22 I25 Y46 N55 H58 R62 G72 F75 W78 K93 N161 Y179 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 i 4.00 BS02 NUC 2 1 Q5 R13 D15 R19 Y20 K23 M44 Y48 F52 Y56 F77 Q81 N84 E85 Y88 T186 Q3 R11 D13 R17 Y18 K21 M42 Y46 F50 Y54 F75 Q79 N82 E83 Y86 T184 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 j 4.00 BS01 NUC 1 1 R4 I10 D11 V12 R13 T16 R19 Y20 K23 L24 I27 Y48 N57 H60 R64 G74 F77 W80 K95 P162 N163 S164 R2 I8 D9 V10 R11 T14 R17 Y18 K21 L22 I25 Y46 N55 H58 R62 G72 F75 W78 K93 P160 N161 S162 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 j 4.00 BS02 NUC 2 1 Q5 R13 D15 R19 Y20 K23 M44 N47 Y48 V51 F52 Y56 F77 Q81 N84 E85 Y88 Q3 R11 D13 R17 Y18 K21 M42 N45 Y46 V49 F50 Y54 F75 Q79 N82 E83 Y86 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 k 4.00 BS01 NUC 1 1 R4 I10 D11 V12 T16 R19 Y20 I27 Y48 N57 H60 R64 G74 F77 W80 K95 N163 S164 Y181 R2 I8 D9 V10 T14 R17 Y18 I25 Y46 N55 H58 R62 G72 F75 W78 K93 N161 S162 Y179 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 k 4.00 BS02 NUC 2 1 Q5 R13 D15 R19 Y20 K23 M44 N47 Y48 V51 F52 Y56 F77 Q81 N84 E85 Y88 G183 T186 Q3 R11 D13 R17 Y18 K21 M42 N45 Y46 V49 F50 Y54 F75 Q79 N82 E83 Y86 G181 T184 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 l 4.00 BS01 NUC 1 1 I10 D11 V12 R13 T16 R19 Y20 I27 Y48 N57 H60 R64 G74 F77 W80 K95 N163 I8 D9 V10 R11 T14 R17 Y18 I25 Y46 N55 H58 R62 G72 F75 W78 K93 N161 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 l 4.00 BS02 NUC 2 1 Q5 R13 D15 Y20 K23 M44 Y48 F52 Y56 F77 Q81 N84 E85 Y88 Q3 R11 D13 Y18 K21 M42 Y46 F50 Y54 F75 Q79 N82 E83 Y86 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 m 4.00 BS01 NUC 1 1 G3 I10 D11 V12 R13 T16 R19 Y20 L24 I27 Y48 N57 H60 R64 G74 F77 W80 N163 S164 Y181 G1 I8 D9 V10 R11 T14 R17 Y18 L22 I25 Y46 N55 H58 R62 G72 F75 W78 N161 S162 Y179 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 m 4.00 BS02 NUC 2 1 Q5 R13 D15 R19 Y20 K23 M44 N47 Y48 V51 Y56 F77 Q81 N84 E85 Y88 T186 Q3 R11 D13 R17 Y18 K21 M42 N45 Y46 V49 Y54 F75 Q79 N82 E83 Y86 T184 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 n 4.00 BS01 NUC 1 1 G3 R4 I10 D11 V12 T16 R19 Y20 L24 I27 Y48 H60 R64 G74 F77 W80 K95 N163 S164 G1 R2 I8 D9 V10 T14 R17 Y18 L22 I25 Y46 H58 R62 G72 F75 W78 K93 N161 S162 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 n 4.00 BS02 NUC 2 1 D15 Y20 K23 M44 N47 Y48 V51 F52 Y56 F77 Q81 N84 E85 Y88 D13 Y18 K21 M42 N45 Y46 V49 F50 Y54 F75 Q79 N82 E83 Y86 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 p 4.00 BS01 NUC 1 1 R4 I10 D11 V12 R13 T16 R19 Y20 I27 Y48 N57 H60 R64 G74 F77 W80 P162 N163 S164 R2 I8 D9 V10 R11 T14 R17 Y18 I25 Y46 N55 H58 R62 G72 F75 W78 P160 N161 S162 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 p 4.00 BS02 NUC 2 1 Q5 R13 D15 Y20 K23 M44 N47 Y48 V51 F52 Y56 F77 Q81 N84 E85 Y88 Q3 R11 D13 Y18 K21 M42 N45 Y46 V49 F50 Y54 F75 Q79 N82 E83 Y86 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 r 4.00 BS01 NUC 1 1 R4 I10 D11 V12 R13 T16 R19 Y20 K23 I27 Y48 N57 H60 R64 G74 F77 W80 K95 N163 R2 I8 D9 V10 R11 T14 R17 Y18 K21 I25 Y46 N55 H58 R62 G72 F75 W78 K93 N161 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 r 4.00 BS02 NUC 2 1 Q5 R13 D15 R19 Y20 K23 M44 Y48 F52 Y56 F77 Q81 N84 E85 Y88 Q3 R11 D13 R17 Y18 K21 M42 Y46 F50 Y54 F75 Q79 N82 E83 Y86 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 t 4.00 BS01 NUC 1 1 I10 D11 V12 R13 T16 R19 Y20 K23 L24 I27 Y48 N57 H60 R64 G74 F77 W80 K95 N163 I8 D9 V10 R11 T14 R17 Y18 K21 L22 I25 Y46 N55 H58 R62 G72 F75 W78 K93 N161 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6wq2 t 4.00 BS02 NUC 2 1 Q5 R13 D15 R19 Y20 K23 M44 Y48 F52 Y56 F77 Q81 N84 E85 Y88 Q3 R11 D13 R17 Y18 K21 M42 Y46 F50 Y54 F75 Q79 N82 E83 Y86 Q914J4 GRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL 6x11 A 2.10 BS01 FE2 A 1 H51 E57 H95 E110 H52 E58 H96 E111 1.13.11.6 Q1LCS4 HMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRA 6x11 A 2.10 BS02 FE2 A 2 C125 C128 C162 C165 C126 C129 C163 C166 1.13.11.6 Q1LCS4 HMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRA 6x11 A 2.10 BS03 2FO A 1 N27 T39 V41 H51 E57 F59 P97 R99 V108 E110 N28 T40 V42 H52 E58 F60 P98 R100 V109 E111 1.13.11.6 Q1LCS4 HMLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPGRA 6xdm A 1.56 BS01 ZN A 1 D177 H179 D265 D170 H172 D258 3.5.1.98 Q92769 32676157 GKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLP 6xdm A 1.56 BS02 CA A 1 D175 D177 H179 S198 F199 H200 D168 D170 H172 S191 F192 H193 3.5.1.98 Q92769 32676157 GKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLP 6xdm A 1.56 BS03 CA A 2 F188 T191 V194 Y223 F181 T184 V187 Y216 3.5.1.98 Q92769 32676157 GKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLP 6xdm A 1.56 BS04 V1D A 1 G28 H29 P30 M31 D100 G139 L140 H141 H142 G150 F151 C152 D177 H179 F206 D265 G301 G302 Y304 G21 H22 P23 M24 D93 G132 L133 H134 H135 G143 F144 C145 D170 H172 F199 D258 G294 G295 Y297 3.5.1.98 Q92769 32676157 GKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLP 6xdm B 1.56 BS01 ZN B 1 D177 H179 D265 D169 H171 D257 3.5.1.98 Q92769 32676157 KKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLP 6xdm B 1.56 BS02 CA B 1 D175 D177 H179 S198 F199 H200 D167 D169 H171 S190 F191 H192 3.5.1.98 Q92769 32676157 KKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLP 6xdm B 1.56 BS03 CA B 2 F188 T191 V194 Y223 F180 T183 V186 Y215 3.5.1.98 Q92769 32676157 KKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLP 6xdm B 1.56 BS04 V1D B 1 G28 P30 M31 E99 D100 G139 H141 H142 G150 F151 C152 D177 H179 F206 D265 L272 G301 G302 Y304 G20 P22 M23 E91 D92 G131 H133 H134 G142 F143 C144 D169 H171 F198 D257 L264 G293 G294 Y296 3.5.1.98 Q92769 32676157 KKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLP 6xdm C 1.56 BS01 ZN C 1 D177 H179 D265 D168 H170 D256 3.5.1.98 Q92769 32676157 KKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLP 6xdm C 1.56 BS02 CA C 1 F188 T191 V194 Y223 F179 T182 V185 Y214 3.5.1.98 Q92769 32676157 KKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLP 6xdm C 1.56 BS03 CA C 2 D175 D177 H179 S198 F199 H200 D166 D168 H170 S189 F190 H191 3.5.1.98 Q92769 32676157 KKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLP 6xdm C 1.56 BS04 V1D C 1 G28 P30 M31 E99 D100 G139 L140 H141 H142 G150 F151 C152 D177 H179 F206 D265 L272 G301 G302 Y304 G19 P21 M22 E90 D91 G130 L131 H132 H133 G141 F142 C143 D168 H170 F197 D256 L263 G292 G293 Y295 3.5.1.98 Q92769 32676157 KKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLP 6xez A 3.50 BS01 NUC P 1 L758 S759 D760 D761 C813 S814 Q815 R836 A840 K849 L854 R858 S861 L862 D865 L755 S756 D757 D758 C810 S811 Q812 R833 A837 K846 L851 R855 S858 L859 D862 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHT 6xez A 3.50 BS02 NUC T 1 N496 K500 S501 N543 G559 R569 K577 G590 S592 F594 Y595 S682 G683 D684 A685 Y689 E857 R914 Y915 M924 N493 K497 S498 N540 G556 R566 K574 G587 S589 F591 Y592 S679 G680 D681 A682 Y686 E854 R911 Y912 M921 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHT 6xez A 3.50 BS03 ZN A 1 H295 C301 C306 C310 H292 C298 C303 C307 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHT 6xez A 3.50 BS04 ZN A 2 C487 H642 C645 C646 C484 H639 C642 C643 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHT 6xez A 3.50 BS05 MG A 1 N209 D218 N206 D215 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHT 6xez A 3.50 BS06 ADP A 1 N52 H75 R116 N209 Y217 D218 N49 H72 R113 N206 Y214 D215 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHT 6xez A 3.50 BS07 1N7 A 1 V204 I223 V233 V201 I220 V230 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHT 6xez A 3.50 BS08 1N7 A 2 R197 V231 K288 Y289 R194 V228 K285 Y286 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHT 6xez B 3.50 BS01 NUC P 1 D50 A54 D45 A49 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 FSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA 6xez B 3.50 BS02 NUC T 1 N43 K61 N38 K56 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 FSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA 6xez D 3.50 BS01 NUC P 1 D50 R57 D45 R52 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 FSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA 6xez E 3.50 BS01 ZN E 1 C5 C8 C26 C29 C5 C8 C26 C29 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRN 6xez E 3.50 BS02 ZN E 2 C50 C55 C72 H75 C50 C55 C72 H75 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRN 6xez E 3.50 BS03 ZN E 3 C16 C19 H33 H39 C16 C19 H33 H39 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRN 6xez E 3.50 BS04 ADP E 1 P283 G285 T286 G287 H290 R443 E540 P283 G285 T286 G287 H290 R443 E540 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRN 6xez E 3.50 BS05 AF3 E 1 G285 T286 K288 G285 T286 K288 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRN 6xez E 3.50 BS06 MG E 1 K288 S289 K288 S289 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRN 6xez E 3.50 BS07 1N7 E 1 V45 Y70 F90 V45 Y70 F90 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRN 6xez F 3.50 BS01 ZN F 1 C5 C8 C26 C29 C5 C8 C26 C29 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRN 6xez F 3.50 BS02 ZN F 2 C50 A52 C55 C72 H75 C50 A52 C55 C72 H75 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRN 6xez F 3.50 BS03 ZN F 3 C16 C19 H33 H39 C16 C19 H33 H39 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRN 6xez F 3.50 BS04 ADP F 1 G282 P283 P284 G285 T286 G287 K288 K320 R442 G282 P283 P284 G285 T286 G287 K288 K320 R442 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRN 6xez F 3.50 BS05 AF3 F 1 G282 P284 T286 K288 D374 G282 P284 T286 K288 D374 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRN 6xez F 3.50 BS06 MG F 1 K288 S289 D374 K288 S289 D374 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 32676607 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRN 6xiw A 2.80 BS01 Y01 A 1 I51 C54 H63 Y64 T539 F540 P541 I19 C22 H31 Y32 T453 F454 P455 Q8IZF0 INKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMACLQKMMRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSRFRNFCRVVVRARFHQLYDLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIQSCSIIHSLRESQQ 6xiw A 2.80 BS02 Y01 A 2 F960 L963 I967 W971 G981 L985 F630 L633 I637 W641 G651 L655 Q8IZF0 INKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMACLQKMMRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSRFRNFCRVVVRARFHQLYDLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIQSCSIIHSLRESQQ 6xiw A 2.80 BS03 Y01 A 3 P916 Y923 I927 P586 Y593 I597 Q8IZF0 INKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMACLQKMMRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSRFRNFCRVVVRARFHQLYDLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIQSCSIIHSLRESQQ 6xl3 A 2.33 BS01 RET A 1 F72 W75 T79 M107 Y126 S129 C130 Y133 W170 Y173 P174 W177 D200 S203 K204 F72 W75 T79 M107 Y126 S129 C130 Y133 W170 Y173 P174 W177 D200 S203 K204 MTQAWLWIGVISMALGSVFFGFGAHNAKNERWQILYTLNFFICLIAAGLYLAMALGLGVNVINGRPTYWVRFVTWFCSTPLLLLDLTFLGRTSLPLTGSLLGANAYMLVTGFVATVTPKPMSYIWYIVSCAAYLAIVYLLAQPYRIAAERKHPRSKQAFRTLVTVHLVLWTLYPIVWILSPEGFSTFTQGSETMFYTLLDIASKVGFGFLSLNTLHTLEQATE 6xl3 A 2.33 BS02 CL A 1 I45 A46 L49 T74 W75 S78 K204 I45 A46 L49 T74 W75 S78 K204 MTQAWLWIGVISMALGSVFFGFGAHNAKNERWQILYTLNFFICLIAAGLYLAMALGLGVNVINGRPTYWVRFVTWFCSTPLLLLDLTFLGRTSLPLTGSLLGANAYMLVTGFVATVTPKPMSYIWYIVSCAAYLAIVYLLAQPYRIAAERKHPRSKQAFRTLVTVHLVLWTLYPIVWILSPEGFSTFTQGSETMFYTLLDIASKVGFGFLSLNTLHTLEQATE 6xl3 B 2.33 BS01 RET B 1 F72 W75 T79 M107 Y126 S129 C130 Y133 W170 Y173 P174 W177 D200 S203 K204 F72 W75 T79 M107 Y126 S129 C130 Y133 W170 Y173 P174 W177 D200 S203 K204 MTQAWLWIGVISMALGSVFFGFGAHNAKNERWQILYTLNFFICLIAAGLYLAMALGLGVNVINGRPTYWVRFVTWFCSTPLLLLDLTFLGRTSLPLTGSLLGANAYMLVTGFVATVTPKPMSYIWYIVSCAAYLAIVYLLAQPYRIAAERKHPRSKQAFRTLVTVHLVLWTLYPIVWILSPEGFSTFTQGSETMFYTLLDIASKVGFGFLSLNTLHTLEQATE 6xl3 B 2.33 BS02 CL B 1 I45 A46 L49 T74 W75 S78 K204 I45 A46 L49 T74 W75 S78 K204 MTQAWLWIGVISMALGSVFFGFGAHNAKNERWQILYTLNFFICLIAAGLYLAMALGLGVNVINGRPTYWVRFVTWFCSTPLLLLDLTFLGRTSLPLTGSLLGANAYMLVTGFVATVTPKPMSYIWYIVSCAAYLAIVYLLAQPYRIAAERKHPRSKQAFRTLVTVHLVLWTLYPIVWILSPEGFSTFTQGSETMFYTLLDIASKVGFGFLSLNTLHTLEQATE 6xqb A 3.40 BS01 NUC E 1 L498 R513 L758 S759 D760 D761 C813 S814 R836 E857 R858 S861 L862 L394 R409 L650 S651 D652 D653 C705 S706 R728 E749 R750 S753 L754 2.7.7.48 P0DTD1 VYRAFDIYVAGFAKFLKRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELMLTNDNTSRYWEPE 6xqb A 3.40 BS02 NUC F 1 N497 K500 S501 R569 L576 K577 I589 G590 S592 F594 Y595 S682 G683 D684 A685 T686 T687 Y689 E857 Y915 N393 K396 S397 R465 L472 K473 I485 G486 S488 F490 Y491 S578 G579 D580 A581 T582 T583 Y585 E749 Y797 2.7.7.48 P0DTD1 VYRAFDIYVAGFAKFLKRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELMLTNDNTSRYWEPE 6xqb A 3.40 BS03 ZN A 1 H295 C301 C306 C310 H191 C197 C202 C206 2.7.7.48 P0DTD1 VYRAFDIYVAGFAKFLKRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELMLTNDNTSRYWEPE 6xqb A 3.40 BS04 ZN A 2 C487 H642 C645 C646 C383 H538 C541 C542 2.7.7.48 P0DTD1 VYRAFDIYVAGFAKFLKRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELMLTNDNTSRYWEPE 6xqb A 3.40 BS05 MG A 1 W617 D618 D761 E811 W513 D514 D653 E703 2.7.7.48 P0DTD1 VYRAFDIYVAGFAKFLKRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELMLTNDNTSRYWEPE 6xqn C 3.30 BS01 III G 1 S244 V245 F247 G248 I249 L253 S67 V68 F70 G71 I72 L76 D6WIX5 DVKTLVNQLYEALNVREHQLQKEVELTTQLETLQQELLPLEEKKLELEQVANRRSNWMAWAGLGLMSVQFGILARLTWWEYSWDIMEPVTYFVTYGTAMAAYAYFVLTRNDVRDRQQLLLLHKKAKKTGFDVNQYNVLKDQIAKLELDLKRLRD 6xqn D 3.30 BS01 III H 1 L240 S244 V245 F247 G248 I249 R252 L253 L66 S70 V71 F73 G74 I75 R78 L79 D6WIX5 GLSDVKTLVNQLYEALNVREHQLQKEVELTTQLETLQQELLPLEEKKLELEQVANRRSNWMAWAGLGLMSVQFGILARLTWWEYSWDIMEPVTYFVTYGTAMAAYAYFVLTREEYILNDVRDRQQLFDVNQYNVLKDQIAKLELDLKRLRD 6xqo I 3.10 BS01 CA I 1 D231 N233 D235 E237 V238 E242 D85 N87 D89 E91 V92 E96 Q9BPX6 KVMEYENRIRAYSTPDKIFRYFATLKVIEVFMTPEDFVRSITADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSCSALTTYFFGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVDTALSFYHMAGASLDKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQRLM 6xqo I 3.10 BS02 CA I 2 D421 D423 N425 E427 E432 D253 D255 N257 E259 E264 Q9BPX6 KVMEYENRIRAYSTPDKIFRYFATLKVIEVFMTPEDFVRSITADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSCSALTTYFFGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVDTALSFYHMAGASLDKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQRLM 6xqo J 3.10 BS01 CA J 1 D185 D187 N189 M191 E193 E196 D96 D98 N100 M102 E104 E107 Q8IYU8 LRKQRFMQFSSLEHEGEYYMTPRDFLFSVMFEQMEKKLTKKDIEDTLSGIQTAGCGSTFFRDLGDKGLISYTEYLFLLTILTKPHSGFHVAFKMLDTDGNEMIEKREFFKLQKIISKQDDLMNTTLQMRFFGKRGQRKLHYKEFRRFMENLQTEIQEMEFLQFSKGLSFMRKEDFAEWLLFFTNTENKDIYWKNVREKLSAGESISLDEFKSFCHFTTHLEDFAIAMQMFSLAHRPVRLAEFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKNR 6xqo J 3.10 BS02 CA J 2 D375 D377 D379 C381 L382 E386 D267 D269 D271 C273 L274 E278 Q8IYU8 LRKQRFMQFSSLEHEGEYYMTPRDFLFSVMFEQMEKKLTKKDIEDTLSGIQTAGCGSTFFRDLGDKGLISYTEYLFLLTILTKPHSGFHVAFKMLDTDGNEMIEKREFFKLQKIISKQDDLMNTTLQMRFFGKRGQRKLHYKEFRRFMENLQTEIQEMEFLQFSKGLSFMRKEDFAEWLLFFTNTENKDIYWKNVREKLSAGESISLDEFKSFCHFTTHLEDFAIAMQMFSLAHRPVRLAEFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKNR 6xtz A 2.21 BS01 O18 A 1 L164 S168 Q171 F195 L259 I359 V363 P510 L90 S94 Q97 F121 L185 I285 V289 P322 Q9VUG1 QFSPNCSAVTHIFQARGIDAIEIPQKPSNERVLRYCESPSVGTCCTYNMETRMAMQSRQQLEGHTKDQISRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVDLLEVMDKFFNTLYQKMFTVLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEVAKKVLNVRLNADCTGALTKMQHCGACKGYTEKPCTNYCVNVIKGCLHYQHEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGREPILDRIVRDIRQRVKDYKKFWSNLPHSVCSNEDIASSSDGMCWNGHTIDRYMHSITTEHGSNPEFTGNPASTKQTAQMASQLSHLKNAIVHLRNAYNGQD 6xuh A 2.38 BS01 PA5 A 1 I156 G157 G158 S159 S209 K210 T211 T214 Q353 E357 K518 I156 G157 G158 S159 S209 K210 T211 T214 Q353 E357 K518 5.3.1.9 P06744 32682158 AALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQREARV 6xuh B 2.38 BS01 O1B B 1 I156 G157 G158 S159 S209 K210 T211 T214 G270 G271 R272 Q353 E357 Q511 K518 I156 G157 G158 S159 S209 K210 T211 T214 G270 G271 R272 Q353 E357 Q511 K518 5.3.1.9 P06744 32682158 AALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQREARV 6xuh C 2.38 BS01 PA5 C 1 I156 G157 G158 S159 S209 K210 T211 T214 Q353 E357 Q511 V514 K518 I156 G157 G158 S159 S209 K210 T211 T214 Q353 E357 Q511 V514 K518 5.3.1.9 P06744 32682158 AALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQREARV 6xuh D 2.38 BS01 O1B D 1 I156 G157 G158 S159 S209 K210 T211 T214 G271 R272 Q353 E357 V514 K518 I156 G157 G158 S159 S209 K210 T211 T214 G271 R272 Q353 E357 V514 K518 5.3.1.9 P06744 32682158 AALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQREARV 6xui A 1.95 BS01 PA5 A 1 I156 G157 G158 S159 S209 K210 T211 T214 Q353 E357 K518 I156 G157 G158 S159 S209 K210 T211 T214 Q353 E357 K518 5.3.1.9 P06744 32682158 AALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQREARV 6xui B 1.95 BS01 PA5 B 1 I156 G157 G158 S159 S209 K210 T211 T214 Q353 E357 K518 I156 G157 G158 S159 S209 K210 T211 T214 Q353 E357 K518 5.3.1.9 P06744 32682158 AALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQREARV 6xui C 1.95 BS01 PA5 C 1 I156 G157 G158 S159 S209 K210 T211 T214 Q353 E357 K518 I156 G157 G158 S159 S209 K210 T211 T214 Q353 E357 K518 5.3.1.9 P06744 32682158 AALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQREARV 6xui D 1.95 BS01 PA5 D 1 I156 G157 G158 S159 S209 K210 T211 T214 Q353 E357 K518 I156 G157 G158 S159 S209 K210 T211 T214 Q353 E357 K518 5.3.1.9 P06744 32682158 AALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQREARV 6xy4 A 2.05 BS01 III B 1 I42 Y46 E49 F50 I53 F56 I57 I74 I75 E77 T78 R84 S86 A90 S91 L94 F133 I38 Y42 E45 F46 I49 F52 I53 I69 I70 E72 T73 R77 S79 A83 S84 L87 F123 A0A3F2YKH3 32390192 NYNIEKVLNVYLRDLRIESLNNNELEILIMIRECCEVIKKDYKTEFNEICNFILQNNKSCYDINDVKNIIIETINSRPSVILASISLLSIIIKKKKDENNDDDLALNELINKFSSYQKDIISFVEKN 6xy6 A 2.91 BS01 III B 1 I42 D45 Y46 E49 F50 I53 F56 I57 I74 I75 E77 T78 S81 D82 R84 S86 A90 S91 L94 F133 K136 N137 I38 D41 Y42 E45 F46 I49 F52 I53 I70 I71 E73 T74 S77 D78 R80 S82 A86 S87 L90 F129 K132 N133 A0A3F2YKH3 32390192 NYNIEKVLNVYLRDLRIESLNNNELEILIMIRECCEVIKKDYKTEFNEICNFILQNNVKSCYDINDVKNIIIETINSDFRPSVILASISLLSIIIKKKKDENNEVVDDDLALNELINKFSSYQKDIISFVEKNKK 6xy6 C 2.91 BS01 III D 1 I42 Y46 E49 F50 I53 F56 I57 I74 I75 T78 S81 D82 R84 S86 A90 S91 L94 F133 N137 K140 I38 Y42 E45 F46 I49 F52 I53 I70 I71 T74 S77 D78 R80 S82 A86 S87 L90 F129 N133 K136 A0A3F2YKH3 32390192 NYNIEKVLNVYLRDLRIESLNNNELEILIMIRECCEVIKKDYKTEFNEICNFILQNNVKSCYDINDVKNIIIETINSDFRPSVILASISLLSIIIKKKKDENNEVVDDDLALNELINKFSSYQKDIISFVEKNKKKNK 6xy6 E 2.91 BS01 III F 1 I42 Y46 E49 F50 I53 F56 I57 I74 I75 E77 T78 R84 S86 V87 A90 S91 L94 F133 N137 I38 Y42 E45 F46 I49 F52 I53 I70 I71 E73 T74 R80 S82 V83 A86 S87 L90 F129 N133 A0A3F2YKH3 32390192 NYNIEKVLNVYLRDLRIESLNNNELEILIMIRECCEVIKKDYKTEFNEICNFILQNNVKSCYDINDVKNIIIETINSDFRPSVILASISLLSIIIKKKKDENNEVVDDDLALNELINKFSSYQKDIISFVEKN 6xy6 G 2.91 BS01 III H 1 I42 Y46 E49 F50 I53 F56 I57 N73 I74 I75 E77 T78 D82 R84 S86 V87 A90 S91 L94 F133 K136 N137 I38 Y42 E45 F46 I49 F52 I53 N69 I70 I71 E73 T74 D78 R80 S82 V83 A86 S87 L90 F129 K132 N133 A0A3F2YKH3 32390192 NYNIEKVLNVYLRDLRIESLNNNELEILIMIRECCEVIKKDYKTEFNEICNFILQNNVKSCYDINDVKNIIIETINSDFRPSVILASISLLSIIIKKKKDENNEVVDDDLALNELINKFSSYQKDIISFVEKNKK 6xy6 I 2.91 BS01 III J 1 I42 Y46 E49 F50 I53 F56 I57 I74 I75 E77 T78 D82 R84 S86 V87 A90 S91 L94 F133 N137 I38 Y42 E45 F46 I49 F52 I53 I70 I71 E73 T74 D78 R80 S82 V83 A86 S87 L90 F129 N133 A0A3F2YKH3 32390192 NYNIEKVLNVYLRDLRIESLNNNELEILIMIRECCEVIKKDYKTEFNEICNFILQNNVKSCYDINDVKNIIIETINSDFRPSVILASISLLSIIIKKKKDENNEVVDDDLALNELINKFSSYQKDIISFVEKN 6xy6 K 2.91 BS01 III L 1 I42 D45 Y46 E49 F50 I53 F56 I57 I74 I75 E77 T78 S81 R84 S86 V87 A90 S91 L94 F133 N137 I38 D41 Y42 E45 F46 I49 F52 I53 I70 I71 E73 T74 S77 R80 S82 V83 A86 S87 L90 F129 N133 A0A3F2YKH3 32390192 NYNIEKVLNVYLRDLRIESLNNNELEILIMIRECCEVIKKDYKTEFNEICNFILQNNVKSCYDINDVKNIIIETINSDFRPSVILASISLLSIIIKKKKDENNEVVDDDLALNELINKFSSYQKDIISFVEKNK 6xy6 M 2.91 BS01 III N 1 I42 Y46 E49 F50 I53 F56 I57 N60 I74 I75 T78 S81 R84 S86 V87 A90 S91 L94 F133 N137 I38 Y42 E45 F46 I49 F52 I53 N56 I70 I71 T74 S77 R80 S82 V83 A86 S87 L90 F129 N133 A0A3F2YKH3 32390192 NYNIEKVLNVYLRDLRIESLNNNELEILIMIRECCEVIKKDYKTEFNEICNFILQNNVKSCYDINDVKNIIIETINSDFRPSVILASISLLSIIIKKKKDENNEVVDDDLALNELINKFSSYQKDIISFVEKN 6xy6 O 2.91 BS01 III P 1 I42 Y46 E49 F50 I53 F56 I57 I74 I75 T78 S81 R84 S86 V87 A90 S91 L94 F133 I37 Y41 E44 F45 I48 F51 I52 I69 I70 T73 S76 R79 S81 V82 A85 S86 L89 F128 A0A3F2YKH3 32390192 YNIEKVLNVYLRDLRIESLNNNELEILIMIRECCEVIKKDYKTEFNEICNFILQNNVKSCYDINDVKNIIIETINSDFRPSVILASISLLSIIIKKKKDENNEVVDDDLALNELINKFSSYQKDIISFVEKN 6y78 A 1.70 BS01 BGC B 1 R162 E184 R186 R50 E72 R74 P17931 PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI 6y78 A 1.70 BS02 GAL B 1 H158 N160 R162 V172 N174 W181 E184 H46 N48 R50 V60 N62 W69 E72 P17931 PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI 6yaf M 9.10 BS01 III P 1 F174 E238 L241 P404 I430 K431 W432 V433 R434 I436 F168 E220 L223 P386 I412 K413 W414 V415 R416 I418 P84092 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGYPQNSETGALKTFITQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIESMEQKLISEEDLGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC 6yle B 3.30 BS01 III K 1 M1 D2 E3 S20 R270 A271 D355 E372 Y374 M1 D2 E3 S20 R249 A250 D322 E339 Y341 P53877 32668200 MDEQVIFTTNTSGTIASVHSFEQINLRQCSTQSRNSCVQVGNKYLFIAQAQKALINVYNLSGSFKRESVEQRLPLPEILKCLEVVENDGVQYDRIQGVNHNLPDFNLPYLLLGSTESGKLYIWELNSGILLNVKPMAHYQSITKIKSILNGKYIITSGNDSRVIIWQTVDLVSPKPLCILHDHTLPVTDFQVSSSQGKFLSCTDTKLFTVSQDATIRCYDLSLIKTPVLLATFTTPYSIKSIVLDPADRACYIGTAEGCFSLNLFYKLKGNAIVNLLQSAGVNTVQKGRVFSLVQRNLYAMGQLVCENVLNSNVSCLEISMDGTLLLIGDTEGKVSIAEIYSKQIIRTIQTLTVGEVTNLLTNPYRLKIPNLQRVIFDGKNKGHLHDIWYQIGEPEADFNAYLEQVKTQESIFSH 6yle C 3.30 BS01 III K 1 I545 L548 K549 V577 L578 E583 R584 V585 S586 I587 I590 I473 L476 K477 V505 L506 E511 R512 V513 S514 I515 I518 P38883 32668200 EFIAVSTLARNLEIAKGNEFHTILATLRSPVYINEQLLKSELSFLVTKILKLIRSGNDFDLWKGCHTSVVTCAYNPLVLSTHGGQLLAAIYSRLEQKTGFYSSVISSSHGKQLFNTLISSVAIIIDLMKNKPTLSREALVPKLKAIIPTLITLSQYEPELVLPVLQRILKRNTTTFKPFTNKFRTVLINLIISDYASLGTKTQRLVCENFAYLHLLDSNWRTGLMSILSQFKPIIQLCGEILDFEQDNELYKLIKSLPEFLPSLKLDFNAPLTLWEIPQRLSLLADMLVAFISLPTPFPIRVPLGGINSLCEVLLGVSNDNELNGVINTILPQIQFQGIRLWEIMVSKYGKCGLSFFEGILSSIELFIPLKKKSNNEIDFNVVGSLKFEFATVFRLVNMILSHLGHQLNIISVISQLIEVALFLSHDKTLIDSLIYTHPELFVCKNSMNWFNEINDFFITALNNWILPSTPHIQILKYSITQSLRLKERFGYIPESFVNLLRCEVLHPGSERVSILPIAISLLKNINDDMFELLCHPKVPVGMVY 6z2v A 2.60 BS01 KHC A 1 L162 G163 V170 A184 E237 L238 L239 N288 L290 D320 L29 G30 V37 A51 E104 L105 L106 N155 L157 D179 2.7.12.1 P49761 RSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLEKSVKNTSIRVVDFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEER 6z6g A 3.06 BS01 NUC U 1 Q291 R292 K302 H306 F418 C419 G420 K439 P440 R592 A593 R595 R600 T642 K643 Y677 K679 E758 H760 H761 V764 K768 L1113 Q1116 V1118 Y1120 D1123 I1125 Q295 R296 K306 H310 F422 C423 G424 K429 P430 R575 A576 R578 R583 T625 K626 Y660 K662 E741 H743 H744 V747 K751 L1069 Q1072 V1074 Y1076 D1079 I1081 2.7.7.48,3.1.-.- A5HC98 32681014 YFQGMDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSATVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYLSDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKMNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIEALALGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDAEMGRSILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYIGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNSPALVLRAYSKNNPDMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDSLSRSAFLQLIIDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMKSHERVTWNDWINLTITGYNRSITIIGEDNKLTYAELCLTRKTPENITISGRKLLGSRHGLKFENMSKIQNYYITYRKKDRHQFVYQIHSHESITRRNEEHMAIRTRIYNEITPVCVVNVAEVDGDQRILIRSLDYLNNDIFSLSRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLLNLNYDNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHSTPIFNIYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLGCLEAVVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPKCFMGNPITRDINWVMFREFINSLPGTDIPPWNVMTENFKKKCIALINSKFSEFTKLM 6z6g A 3.06 BS02 NUC X 1 N380 I863 N384 I846 2.7.7.48,3.1.-.- A5HC98 32681014 YFQGMDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSATVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYLSDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKMNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIEALALGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDAEMGRSILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYIGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNSPALVLRAYSKNNPDMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDSLSRSAFLQLIIDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMKSHERVTWNDWINLTITGYNRSITIIGEDNKLTYAELCLTRKTPENITISGRKLLGSRHGLKFENMSKIQNYYITYRKKDRHQFVYQIHSHESITRRNEEHMAIRTRIYNEITPVCVVNVAEVDGDQRILIRSLDYLNNDIFSLSRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLLNLNYDNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHSTPIFNIYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLGCLEAVVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPKCFMGNPITRDINWVMFREFINSLPGTDIPPWNVMTENFKKKCIALINSKFSEFTKLM 6z6g A 3.06 BS03 NUC H 1 H312 N313 N318 A320 K323 K368 K370 R372 I378 N380 K381 K382 L383 W395 E396 Q397 Q398 L471 K472 Q506 T513 N517 S520 V521 Y524 R526 R531 M534 C535 A536 N537 N538 N1308 Q1313 S1314 I1511 L1512 F1513 H1515 K1516 H316 N317 N322 A324 K327 K372 K374 R376 I382 N384 K385 K386 L387 W399 E400 Q401 Q402 L461 K462 Q496 T503 N507 S510 V511 Y514 R516 R521 M524 C525 A526 N527 N528 N1264 Q1269 S1270 I1454 L1455 F1456 H1458 K1459 2.7.7.48,3.1.-.- A5HC98 32681014 YFQGMDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSATVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYLSDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKMNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIEALALGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDAEMGRSILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYIGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNSPALVLRAYSKNNPDMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDSLSRSAFLQLIIDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMKSHERVTWNDWINLTITGYNRSITIIGEDNKLTYAELCLTRKTPENITISGRKLLGSRHGLKFENMSKIQNYYITYRKKDRHQFVYQIHSHESITRRNEEHMAIRTRIYNEITPVCVVNVAEVDGDQRILIRSLDYLNNDIFSLSRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLLNLNYDNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHSTPIFNIYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLGCLEAVVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPKCFMGNPITRDINWVMFREFINSLPGTDIPPWNVMTENFKKKCIALINSKFSEFTKLM 6z6g A 3.06 BS04 ZN A 1 C2064 H2169 D2178 H2182 C1961 H2066 D2075 H2079 2.7.7.48,3.1.-.- A5HC98 32681014 YFQGMDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSATVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYLSDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKMNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIEALALGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDAEMGRSILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYIGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNSPALVLRAYSKNNPDMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDSLSRSAFLQLIIDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMKSHERVTWNDWINLTITGYNRSITIIGEDNKLTYAELCLTRKTPENITISGRKLLGSRHGLKFENMSKIQNYYITYRKKDRHQFVYQIHSHESITRRNEEHMAIRTRIYNEITPVCVVNVAEVDGDQRILIRSLDYLNNDIFSLSRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLLNLNYDNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHSTPIFNIYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLGCLEAVVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPKCFMGNPITRDINWVMFREFINSLPGTDIPPWNVMTENFKKKCIALINSKFSEFTKLM 6z6g A 3.06 BS05 MG A 1 A1059 D1060 D1188 E1237 A1015 D1016 D1144 E1193 2.7.7.48,3.1.-.- A5HC98 32681014 YFQGMDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPSATVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYLSDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKMNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIEALALGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDAEMGRSILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYIGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNSPALVLRAYSKNNPDMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDSLSRSAFLQLIIDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMKSHERVTWNDWINLTITGYNRSITIIGEDNKLTYAELCLTRKTPENITISGRKLLGSRHGLKFENMSKIQNYYITYRKKDRHQFVYQIHSHESITRRNEEHMAIRTRIYNEITPVCVVNVAEVDGDQRILIRSLDYLNNDIFSLSRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLLNLNYDNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHSTPIFNIYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLGCLEAVVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPKCFMGNPITRDINWVMFREFINSLPGTDIPPWNVMTENFKKKCIALINSKFSEFTKLM 6z8k A 3.02 BS01 NUC C 1 Q291 R292 K302 H306 F418 C419 G420 K439 P440 R592 A593 R595 R600 T642 K643 Y677 K679 E758 H760 H761 V764 K768 L1113 Q1116 V1118 Y1120 D1123 Q291 R292 K302 H306 F418 C419 G420 K425 P426 R570 A571 R573 R578 T620 K621 Y655 K657 E736 H738 H739 V742 K746 L1060 Q1063 V1065 Y1067 D1070 2.7.7.48,3.1.-.- A5HC98 32681014 MDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPATVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYLSDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIELGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDAEMDPSDIMGETSDMRGRSILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYINLGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNLKLIHHSPALVLRAYSKNNPDPTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSHKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDSLSRSAFLQLIIDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMKSHERVTWNDWINLTITGYNRSITIIGEDNKLTYAELCLTRKTPENITISGRKLLGSRHGLKFENMSKIQNYYITYRKKDRHQFVYQIHSHESITRRNEEHMAIRTRIYNEITPVCVVNVAEVDGDQRILIRSLDYLNNDIFSLSRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLLNLNYDNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHSTPIFNIYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLGCLEAVVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPKCFMGNPITRDINWVMFREFINSLPGTDIPPWNVMTENFKKKCIALINSKFSEFTKLM 6z8k A 3.02 BS02 NUC H 1 H312 N313 N318 A320 K323 L367 K368 R372 I378 M379 N380 K381 K382 L383 W395 E396 Q397 Q398 L471 K472 Q506 N517 S520 V521 Y524 R526 R531 M534 C535 A536 N537 N538 N1308 Q1313 S1314 I1511 L1512 F1513 H1515 K1516 H312 N313 N318 A320 K323 L367 K368 R372 I378 M379 N380 K381 K382 L383 W395 E396 Q397 Q398 L457 K458 Q492 N503 S506 V507 Y510 R512 R517 M520 C521 A522 N523 N524 N1255 Q1260 S1261 I1458 L1459 F1460 H1462 K1463 2.7.7.48,3.1.-.- A5HC98 32681014 MDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPATVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYLSDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIELGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDAEMDPSDIMGETSDMRGRSILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYINLGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNLKLIHHSPALVLRAYSKNNPDPTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSHKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDSLSRSAFLQLIIDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMKSHERVTWNDWINLTITGYNRSITIIGEDNKLTYAELCLTRKTPENITISGRKLLGSRHGLKFENMSKIQNYYITYRKKDRHQFVYQIHSHESITRRNEEHMAIRTRIYNEITPVCVVNVAEVDGDQRILIRSLDYLNNDIFSLSRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLLNLNYDNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHSTPIFNIYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLGCLEAVVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPKCFMGNPITRDINWVMFREFINSLPGTDIPPWNVMTENFKKKCIALINSKFSEFTKLM 6z8k A 3.02 BS03 NUC T 1 T836 K841 S842 F948 I960 F961 V962 K968 R976 K979 E992 P993 G994 G1146 N1149 Y1150 I1266 Y1269 E1270 A1273 S1277 K1284 R1424 S1425 K1705 I1706 K1707 T814 K819 S820 F905 I917 F918 V919 K925 R933 K936 E949 P950 G951 G1093 N1096 Y1097 I1213 Y1216 E1217 A1220 S1224 K1231 R1371 S1372 K1632 I1633 K1634 2.7.7.48,3.1.-.- A5HC98 32681014 MDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPATVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYLSDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIELGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDAEMDPSDIMGETSDMRGRSILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYINLGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNLKLIHHSPALVLRAYSKNNPDPTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSHKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDSLSRSAFLQLIIDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMKSHERVTWNDWINLTITGYNRSITIIGEDNKLTYAELCLTRKTPENITISGRKLLGSRHGLKFENMSKIQNYYITYRKKDRHQFVYQIHSHESITRRNEEHMAIRTRIYNEITPVCVVNVAEVDGDQRILIRSLDYLNNDIFSLSRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLLNLNYDNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHSTPIFNIYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLGCLEAVVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPKCFMGNPITRDINWVMFREFINSLPGTDIPPWNVMTENFKKKCIALINSKFSEFTKLM 6z8k A 3.02 BS04 NUC P 1 Y750 K754 S840 R958 W1064 Q1145 G1146 N1149 H1185 S1186 D1187 V1239 S1240 R1254 F1255 T1258 D1262 C1263 A1264 V1472 K1474 F1494 S1497 Y1696 Y728 K732 S818 R915 W1011 Q1092 G1093 N1096 H1132 S1133 D1134 V1186 S1187 R1201 F1202 T1205 D1209 C1210 A1211 V1419 K1421 F1441 S1444 Y1625 2.7.7.48,3.1.-.- A5HC98 32681014 MDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPATVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYLSDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIELGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDAEMDPSDIMGETSDMRGRSILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYINLGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNLKLIHHSPALVLRAYSKNNPDPTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSHKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDSLSRSAFLQLIIDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMKSHERVTWNDWINLTITGYNRSITIIGEDNKLTYAELCLTRKTPENITISGRKLLGSRHGLKFENMSKIQNYYITYRKKDRHQFVYQIHSHESITRRNEEHMAIRTRIYNEITPVCVVNVAEVDGDQRILIRSLDYLNNDIFSLSRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLLNLNYDNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHSTPIFNIYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLGCLEAVVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPKCFMGNPITRDINWVMFREFINSLPGTDIPPWNVMTENFKKKCIALINSKFSEFTKLM 6z8k A 3.02 BS05 ZN A 1 C2064 H2169 D2178 H2182 C1977 H2082 D2091 H2095 2.7.7.48,3.1.-.- A5HC98 32681014 MDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPATVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYLSDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIELGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDAEMDPSDIMGETSDMRGRSILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYINLGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNLKLIHHSPALVLRAYSKNNPDPTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSHKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDSLSRSAFLQLIIDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMKSHERVTWNDWINLTITGYNRSITIIGEDNKLTYAELCLTRKTPENITISGRKLLGSRHGLKFENMSKIQNYYITYRKKDRHQFVYQIHSHESITRRNEEHMAIRTRIYNEITPVCVVNVAEVDGDQRILIRSLDYLNNDIFSLSRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLLNLNYDNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHSTPIFNIYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLGCLEAVVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPKCFMGNPITRDINWVMFREFINSLPGTDIPPWNVMTENFKKKCIALINSKFSEFTKLM 6z8k A 3.02 BS06 MG A 1 A1059 D1060 D1188 E1237 A1006 D1007 D1135 E1184 2.7.7.48,3.1.-.- A5HC98 32681014 MDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEYRNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSNESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELYPTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVAHGDFTLTAPWCKTGCPEFWKHPIYKEFKMSMPVPERRLFEESVKFNAYESERWNTNLVKIREYTKKDYSEHISKSAKNIFLASGFYKQPNKNEISEGWTLMVERVQDQREISKSLHDQKPSIHFIWGAHNPGNSNNATFKLILLSKSLQSIKGISTYTEAFKSLGKMMDIGDKAIEYEEFCMSLKSKARSSWKQIMNKKLEPKQINNALVLWEQQFMINNDLIDKSEKLKLFKNFCGIGKSKPKILDFDDANMYLASLTMMEQSKKILSKSNGLKPDNFILNEFGSRIKDANKETYDNMHKIFETGYWQCISDFSTLMKNILSVSQYNRHNTFRIAMCANNNVFAIVFPATVVYSIIVLHKEEENIFNPGCLHGTFKCMNGYISISRAIRLDKERCQRIVSSPGLFLTTCLLFKHDNPTLVMSDIMNFSIYTSLSITKSVLSLTEPARYMIMNSLAISSNVKDYIAEKFSPYTKTLFSVYMTRLIKNACFDAYDQRQRVQLRDIYLSDYDITQKGIKDNRELTSIWFPGSVTLKEYLTQIYLPFYFNAKGLHEKHHVMVDLAKTILEIECEQRENIKEIWSTNCTKQTVNLKILIHSLCKNLLADTSRHNHLRNRIENRNNFRRSITTISTFTSSKSCLKIGDFRKEKELQSVKQKKILEVQSRKNYEMLRNAMPNYTDYISTKVFDRLYELLDKKVLTDKPVIEQIMDMMIDHKKFYFTFFNKGQKTSKDREIFVGEYEAKMCMYAVERIAKERCKLNPDEMISEPGDGKLKVLEQKSEQEIRFLVETTRQKNREIDEAIELGKIEKLSLGKAKGLKMEINADMSKWSAQDVFYKYFWLIALDPILYPQEKERILYFMCNYMDKELILPDELLFNLLDQKVAYQNDIIATMTNQLNSNTVLIKRNWLQGNFNYTSSYVHSCAMSVYKEILKEAITLLDGSILVNSLVHSDDNQTSITIVQDKMENDKIIDFAMKEFERACLTFGCQANMKKTYVTNCIKEFVSLFNLYGEPFSIYGRFLLTSVGDCAYIGPYEDLASRISSAQTAIKHGCPPSLAWVSIAISHWMTSLTYNMLPGQSNDPIDYFPAENRKDIPIELNGVLDAPLSMISTVGLESGNLYFLIKLLSKYTPVMQKRESVVNQIAEVKNWKVEDLTDNEIFRLKILRYLVLDAEMDPSDIMGETSDMRGRSILTPRKFTTAGSLRKLYSFSKYQDRLSSPGGMVELFTYLLEKPELLVTKGEDMKDYMESVIFRYNSKRFKESLSIQNPAQLFIEQILFSHKPVIDFSGIRDKYINLGKVTFTEAYRLLMRDLSSLELTNDDIQVIYSYIILNDPMMITIANTHILSIYGSPQRRMGMSCSTMPEFRNLKLIHHSPALVLRAYSKNNPDPTEMARDLVHLKEFVENTNLEEKMKVRIAMNEAEKGQRDIVFELKEMTRFYQVCYEYVKSHKIKVFILPAKSYTTTDFCSLMQGNLIKDKEWYTVHYLKQILSGGHKAIMQHNATSEQNIAFECFKLITHFADSFIDSLSRSAFLQLIIDEFSYKDVKVSKLYDIIKNGYNRTDFIPLLFRTGDLRQADLDKYDAMKSHERVTWNDWINLTITGYNRSITIIGEDNKLTYAELCLTRKTPENITISGRKLLGSRHGLKFENMSKIQNYYITYRKKDRHQFVYQIHSHESITRRNEEHMAIRTRIYNEITPVCVVNVAEVDGDQRILIRSLDYLNNDIFSLSRIKVGLDEFATIKKAHFSKMVSFEGPPIKTGLLDLTELMKSQDLLNLNYDNIRNSNLISFSKLICCEGSDNINDGLEFLSDDPMNFTEGEAIHSTPIFNIYYSKRGERHMTYRNAIKLLIERETKIFEEAFTFSENGFISPENLGCLEAVVSLIKLLKTNEWSTVIDKCIHICLIKNGMDHMYHSFDVPKCFMGNPITRDINWVMFREFINSLPGTDIPPWNVMTENFKKKCIALINSKFSEFTKLM 6zad A 2.24 BS01 QDW A 1 M752 P758 W760 I777 K779 Y813 I825 E826 V827 V828 M900 I910 D911 M592 P598 W600 I617 K619 Y653 I665 E666 V667 V668 M740 I750 D751 2.7.1.153 O35904 32676144 DRVKKLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGNRALLVNVKFEGSEESFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYALQVNGRHEYLYGNYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVDCPIAWANLMLFDYKDQLKTGERCLYMWPSVLLNPAGTVRGNPNTESAAALVIYLPEVAPHPVYFPALEKILELGRHGERGRITEEEQLQLREILERGELYEHEKDLVWKMRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVN 6zcm A 1.24 BS01 QF2 A 1 K361 S362 N363 N367 W377 S378 T379 L380 R404 W428 P431 M434 L439 D476 K18 S19 N20 N24 W34 S35 T36 L37 R61 W85 P88 M91 L96 D133 Q96MU7 GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDESIDLYQVIHKM 6zcm B 1.24 BS01 QF2 B 1 K361 S362 N363 W377 S378 T379 L380 R404 W428 L430 P431 M434 D476 K18 S19 N20 W34 S35 T36 L37 R61 W85 L87 P88 M91 D133 Q96MU7 GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDESIDLYQVIHKM 6zcn A 1.60 BS01 6MZ A 1 K361 S362 N363 N367 W377 S378 L380 R404 W428 M434 D476 K18 S19 N20 N24 W34 S35 L37 R61 W85 M91 D133 Q96MU7 GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDESIDLYQVIHKM 6zcn B 1.60 BS01 6MZ B 1 K361 S362 N363 N367 W377 S378 L380 W428 M434 D476 K18 S19 N20 N24 W34 S35 L37 W85 M91 D133 Q96MU7 GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDESIDLYQVIHKM 6zgc A 2.67 BS01 H8H A 1 V214 Y219 V222 A233 K235 L263 L281 T283 H284 Y285 H286 G289 S290 K340 L343 A353 V10 Y15 V18 A29 K31 L59 L77 T79 H80 Y81 H82 G85 S86 K136 L139 A149 2.7.11.30 Q04771 ARDITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKID 6zgc B 2.67 BS01 H8H B 1 V214 G215 V222 A233 K235 L263 L281 T283 H284 Y285 H286 E287 G289 S290 K340 L343 A353 V12 G13 V20 A31 K33 L61 L78 T80 H81 Y82 H83 E84 G86 S87 K137 L140 A150 2.7.11.30 Q04771 TVARDITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKID 6zgc C 2.67 BS01 H8H C 1 V214 V222 A233 K235 L263 L281 T283 H284 Y285 H286 E287 M288 G289 K340 L343 A353 V14 V22 A33 K35 L63 L81 T83 H84 Y85 H86 E87 M88 G89 K140 L143 A153 2.7.11.30 Q04771 QRTVARDITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI 6zgc D 2.67 BS01 H8H D 1 V214 G215 V222 A233 K235 E248 L263 L281 T283 H284 Y285 H286 E287 M288 G289 S290 K340 L343 A353 V12 G13 V18 A29 K31 E44 L59 L77 T79 H80 Y81 H82 E83 M84 G85 S86 K136 L139 A149 2.7.11.30 Q04771 TVARDITLLECVGKYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI 6zgv A 2.30 BS01 GAL A 1 E43 H44 D46 Y47 C182 G183 M185 D186 Y236 G346 E42 H43 D45 Y46 C181 G182 M184 D185 Y235 G342 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgv A 2.30 BS02 HFK A 1 T77 S79 G81 D83 R105 W106 Y109 V129 S131 L135 S141 S142 R228 T76 S78 G80 D82 R104 W105 Y108 V128 S130 L134 S140 S141 R227 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgv B 2.30 BS01 GAL B 1 E43 H44 D46 Y47 C182 G183 M185 D186 Y236 G346 E42 H43 D45 Y46 C177 G178 M180 D181 Y231 G341 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgv B 2.30 BS02 HFK B 1 G81 D83 R105 W106 Y109 V129 S131 L135 G136 S141 S142 L145 G80 D82 R100 W101 Y104 V124 S126 L130 G131 S136 S137 L140 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgv E 2.30 BS01 GAL E 1 E43 H44 D46 Y47 C182 G183 M185 D186 Y236 G346 E42 H43 D45 Y46 C181 G182 M184 D185 Y235 G345 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgv E 2.30 BS02 HFK E 1 S79 G81 D83 R105 W106 Y109 V129 S131 L135 G136 S141 S142 L145 R228 S78 G80 D82 R104 W105 Y108 V128 S130 L134 G135 S140 S141 L144 R227 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgv D 2.30 BS01 QKZ D 1 L40 M55 G196 L213 S214 D215 P216 L218 V220 Y300 L355 Q382 A383 L33 M48 G176 L193 S194 D195 P196 L198 V200 Y280 L335 Q362 A363 2.7.1.6 P51570 QVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgw A 2.30 BS01 GAL A 1 R37 E43 H44 D46 Y47 C182 G183 M185 D186 Y236 G346 R36 E42 H43 D45 Y46 C181 G182 M184 D185 Y235 G345 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgw A 2.30 BS02 HFK A 1 T77 S79 D83 R105 W106 Y109 V129 S131 L135 S141 S142 L145 R228 T76 S78 D82 R104 W105 Y108 V128 S130 L134 S140 S141 L144 R227 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgw B 2.30 BS01 GAL B 1 E43 H44 D46 Y47 C182 G183 D186 Y236 G346 E41 H42 D44 Y45 C180 G181 D184 Y234 G344 2.7.1.6 P51570 ALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgw B 2.30 BS02 HFK B 1 S79 R105 W106 Y109 V129 S131 L135 G136 S141 S142 L145 S77 R103 W104 Y107 V127 S129 L133 G134 S139 S140 L143 2.7.1.6 P51570 ALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgw E 2.30 BS01 GAL E 1 R37 E43 H44 D46 C182 G183 M185 D186 Y236 G346 R36 E42 H43 D45 C181 G182 M184 D185 Y235 G345 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgw E 2.30 BS02 HFK E 1 S79 G81 D83 R105 W106 Y109 V129 S131 L135 G136 S141 S142 L145 R228 S78 G80 D82 R104 W105 Y108 V128 S130 L134 G135 S140 S141 L144 R227 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgw D 2.30 BS01 QKW D 1 L40 M55 G196 L213 S214 D215 P216 L218 A219 V220 F303 L355 Q382 A383 L32 M47 G175 L192 S193 D194 P195 L197 A198 V199 F282 L334 Q361 A362 2.7.1.6 P51570 PQVAELLAEARRAFREEFEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgx A 1.86 BS01 GAL A 1 R37 E43 H44 D46 Y47 C182 G183 M185 D186 Y236 G346 R36 E42 H43 D45 Y46 C181 G182 M184 D185 Y235 G345 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgx A 1.86 BS02 HFK A 1 T61 S79 G81 D83 R105 W106 Y109 V129 S131 L135 S141 S142 L145 T60 S78 G80 D82 R104 W105 Y108 V128 S130 L134 S140 S141 L144 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgx B 1.86 BS01 GAL B 1 E43 H44 D46 Y47 C182 G183 M185 D186 Y236 G346 E42 H43 D45 Y46 C181 G182 M184 D185 Y235 G345 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgx B 1.86 BS02 HFK B 1 G81 R105 W106 Y109 V129 S131 L135 S141 S142 L145 G80 R104 W105 Y108 V128 S130 L134 S140 S141 L144 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgx D 1.86 BS01 S6V D 1 L40 M55 G196 L213 D215 P216 L218 A219 V220 L295 Y300 L355 Q382 A383 L24 M39 G163 L180 D182 P183 L185 A186 V187 L262 Y267 L322 Q349 A350 2.7.1.6 P51570 PQVAELLAEAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPLVSLLTTQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgx E 1.86 BS01 GAL E 1 E43 H44 D46 Y47 C182 G183 M185 D186 Y236 G345 G346 E42 H43 D45 Y46 C181 G182 M184 D185 Y235 G344 G345 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgx E 1.86 BS02 HFK E 1 G81 D83 R105 W106 Y109 V129 S131 L135 G136 S141 S142 L145 R228 G80 D82 R104 W105 Y108 V128 S130 L134 G135 S140 S141 L144 R227 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgy A 2.30 BS01 GAL A 1 R37 E43 H44 D46 Y47 C182 G183 M185 D186 Y236 G346 R36 E42 H43 D45 Y46 C181 G182 M184 D185 Y235 G345 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgy A 2.30 BS02 HFK A 1 T77 S79 D83 R105 W106 Y109 V129 S131 L135 G136 S141 S142 L145 T76 S78 D82 R104 W105 Y108 V128 S130 L134 G135 S140 S141 L144 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgy A 2.30 BS03 QL5 A 1 L213 S214 D215 L218 L295 F303 L355 L212 S213 D214 L217 L294 F302 L354 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgy B 2.30 BS01 GAL B 1 E43 H44 D46 Y47 C182 G183 M185 D186 Y236 G346 E42 H43 D45 Y46 C181 G182 M184 D185 Y235 G345 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgy B 2.30 BS02 HFK B 1 D83 R105 W106 Y109 V129 S131 S141 S142 L145 D82 R104 W105 Y108 V128 S130 S140 S141 L144 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgy B 2.30 BS03 QL5 B 1 L40 L213 D215 L218 A219 L295 F303 L355 S381 Q382 L39 L212 D214 L217 A218 L294 F302 L354 S380 Q381 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgy E 2.30 BS01 GAL E 1 R37 E43 H44 D46 Y47 C182 G183 M185 D186 Y236 G346 R36 E42 H43 D45 Y46 C181 G182 M184 D185 Y235 G345 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgy E 2.30 BS02 HFK E 1 S79 G81 D83 R105 W106 Y109 V129 S131 L135 G136 S141 S142 L145 R228 S78 G80 D82 R104 W105 Y108 V128 S130 L134 G135 S140 S141 L144 R227 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgz A 2.30 BS01 GAL A 1 R37 E43 H44 D46 Y47 C182 G183 M185 D186 Y236 G346 R36 E42 H43 D45 Y46 C181 G182 M184 D185 Y235 G342 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgz A 2.30 BS02 HFK A 1 T77 S79 D83 R105 W106 Y109 V129 S131 L135 S141 S142 L145 R228 T76 S78 D82 R104 W105 Y108 V128 S130 L134 S140 S141 L144 R227 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgz B 2.30 BS01 GAL B 1 R37 E43 H44 D46 Y47 C182 G183 D186 Y236 G346 R36 E42 H43 D45 Y46 C178 G179 D182 Y232 G342 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgz B 2.30 BS02 HFK B 1 R105 W106 Y109 V129 L135 G136 S141 S142 L145 R101 W102 Y105 V125 L131 G132 S137 S138 L141 2.7.1.6 P51570 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgz E 2.30 BS01 GAL E 1 E43 H44 D46 Y47 C182 G183 M185 D186 Y236 G346 E41 H42 D44 Y45 C180 G181 M183 D184 Y234 G344 2.7.1.6 P51570 ALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgz E 2.30 BS02 HFK E 1 T77 G81 D83 R105 W106 Y109 V129 S131 L135 G136 S141 S142 L145 R228 T75 G79 D81 R103 W104 Y107 V127 S129 L133 G134 S139 S140 L143 R226 2.7.1.6 P51570 ALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zgz D 2.30 BS01 SSY D 1 M55 L213 S214 D215 P216 L218 V220 Y300 L355 Q382 M47 L189 S190 D191 P192 L194 V196 Y276 L331 Q358 2.7.1.6 P51570 PQVAELLAEARRAFREEFEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPLVSLLTTQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGAASLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATFYLSQAADGAKVLCL 6zjf A 1.75 BS01 QM2 A 1 K37 L39 V47 A60 K62 E111 Y112 A113 A114 G116 L165 D179 K21 L23 V31 A44 K46 E95 Y96 A97 A98 G100 L149 D163 2.7.11.1 O94768 TENLYFQSMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFENLFHPEETSS 6zl6 A 1.70 BS01 UDP A 1 T178 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 T178 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zl6 A 1.70 BS02 NAD A 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zl6 B 1.70 BS01 UDP B 1 R88 T178 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 R88 T178 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zl6 B 1.70 BS02 NAD B 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zla A 2.20 BS01 NAD A 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N97 V101 I120 S121 T122 Y145 K149 Y172 V175 R181 M184 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYKGDAAWS 6zla B 2.20 BS01 NAD B 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N97 V101 I120 S121 T122 Y145 K149 Y172 V175 R181 M184 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zla C 2.20 BS01 NAD C 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N97 V101 I120 S121 T122 Y145 K149 Y172 T174 V175 R181 M184 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zla D 2.20 BS01 NAD D 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 F177 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N98 V102 I121 S122 T123 Y146 K150 Y173 F174 V176 R182 M185 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYKGDAAWSH 6zld A 1.80 BS01 NAD A 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 P85 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 P85 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zld A 1.80 BS02 UGA A 1 P85 V87 R88 T126 S127 S128 Y149 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 V87 R88 T126 S127 S128 Y149 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zld B 1.80 BS01 NAD B 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 D62 I63 L81 A82 A83 P85 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 D62 I63 L81 A82 A83 P85 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zld B 1.80 BS02 UGA B 1 P85 V87 R88 T126 S127 S128 Y149 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 V87 R88 T126 S127 S128 Y149 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zlj A 1.70 BS01 NAD A 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 K153 Y176 T178 V179 R185 M188 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPFGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zlj A 1.70 BS02 UGF A 1 P85 V87 R88 T126 S127 S128 F149 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 V87 R88 T126 S127 S128 F149 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPFGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zlj B 1.70 BS01 NAD B 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 K153 Y176 T178 V179 R185 M188 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPFGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zlj B 1.70 BS02 UGF B 1 P85 R88 T126 S127 S128 F149 Y176 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 R88 T126 S127 S128 F149 Y176 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPFGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zlk A 1.50 BS01 NAD A 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 D62 I63 L81 A82 A83 P85 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 D62 I63 L81 A82 A83 P85 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zlk A 1.50 BS02 UGA A 1 P85 R88 T126 S127 Y149 Y176 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 R88 T126 S127 Y149 Y176 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zlk A 1.50 BS03 UGB A 1 P85 G86 V87 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 G86 V87 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zlk B 1.50 BS01 NAD B 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zlk B 1.50 BS02 UGA B 1 P85 R88 T126 S127 Y149 Y176 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 R88 T126 S127 Y149 Y176 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zlk B 1.50 BS03 UGB B 1 P85 G86 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 G86 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zlk C 1.50 BS01 NAD C 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zlk C 1.50 BS02 UGA C 1 P85 R88 T126 S127 Y149 Y176 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 R88 T126 S127 Y149 Y176 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zlk C 1.50 BS03 UGB C 1 P85 G86 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 G86 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLY 6zlk D 1.50 BS01 NAD D 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zlk D 1.50 BS02 UGA D 1 P85 R88 T126 S127 Y149 Y176 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 R88 T126 S127 Y149 Y176 F177 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zlk D 1.50 BS03 UGB D 1 P85 G86 V87 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 G86 V87 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zll A 1.85 BS01 UGB A 1 P85 G86 V87 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 G86 V87 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYKGDAAWS 6zll A 1.85 BS02 NAD A 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 P85 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 P85 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYKGDAAWS 6zll B 1.85 BS01 UGB B 1 P85 G86 V87 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 G86 V87 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zll B 1.85 BS02 NAD B 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zll C 1.85 BS01 UGB C 1 G86 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 G86 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zll C 1.85 BS02 NAD C 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYK 6zll D 1.85 BS01 UGB D 1 P85 V87 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 P85 V87 R88 T126 S127 S128 Y149 Y176 T178 R185 M188 A189 R192 T204 I205 F206 Q211 R213 I250 E276 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYKGDAAWS 6zll D 1.85 BS02 NAD D 1 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 G7 G10 F11 I12 D32 H33 F34 I35 K43 E61 D62 I63 L81 A82 A83 N101 V105 I124 S125 T126 Y149 K153 Y176 T178 V179 R185 M188 J8BY31 32661196 MKILVTGAAGFIGSHLCQALLKNSAYHVVGIDHFIGPTPATLKTGNIQSLELNSRFQFIREDILNTDLSKLLQDIDVVYHLAAIPGVRTSWGKDFQPYVTNNIMVTQQLLEACKHIKLDKFIHISTSSVYGEKSGAVSEDLLPIPLSPYGVTKLSGEHLCHVYHKNFHIPIVILRYFTVYGPRQRPDMAFHRLIKQMLEDKPLTIFGDGTQTRDFTYIDDCIRGTVAALETKKNIIGEVINIGGKEQASILDIISMLEKISGKSATKNFLKSVPGEPKQTWADISKASTLLQYSPTVSLSDGLEAEYDYIKQLYKGDAAWS 6zlw c 2.60 BS01 ZN c 1 C23 C26 C74 C77 C22 C25 C73 C76 P62854 32680882 TKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPPRFR 6zlw f 2.60 BS01 ZN f 1 C21 C24 C39 C42 C19 C22 C37 C40 P62273 32680882 HQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD 6zlw g 2.60 BS01 ZN g 1 V130 F131 C141 G142 V53 F54 C64 G65 P62979 32680882 KKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMASHFDRHYCGKCCLTYC 6zn5 D 3.20 BS01 III i 1 E105 V106 I109 P111 Q113 T122 E146 V147 I151 E47 V48 I51 P53 Q55 T64 E88 V89 I93 P15880 32680882 EWMPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKT 6zn5 F 3.20 BS01 III i 1 A114 V115 R116 L142 M150 A112 V113 R114 L140 M148 4.2.99.18 P23396 32680882 VQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDPTGKIGPKKPLPDHVSIVEPKDEILPTTPISEQK 6zn5 c 3.20 BS01 ZN c 1 C23 C26 C74 C77 C22 C25 C73 C76 P62854 32680882 TKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPPRFR 6zn5 f 3.20 BS01 ZN f 1 C21 C24 C39 C42 C19 C22 C37 C40 P62273 32680882 HQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD 6zn5 g 3.20 BS01 ZN g 1 E125 C126 K143 E48 C49 K66 Q5RKT7 32680882 KKRKKKSCTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMASHFDRHYCGKCCLTYC 6znl A 3.80 BS01 ADP A 1 G17 S18 V20 K22 Q142 D162 K215 K218 E219 G302 G303 S304 L306 F307 L337 G11 S12 V14 K16 Q136 D156 K209 K212 E213 G296 G297 S298 L300 F301 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6znl B 3.80 BS01 ADP B 1 G17 V20 K22 Q142 D159 G161 D162 K218 E219 G303 S304 F307 L337 G11 V14 K16 Q136 D153 G155 D156 K212 E213 G297 S298 F301 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6znl C 3.80 BS01 ADP C 1 G17 S18 K22 Q142 G161 D162 K218 E219 G302 G303 S304 F307 L337 G16 S17 K21 Q141 G160 D161 K217 E218 G301 G302 S303 F306 L336 F2Z5G5 ESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6znl D 3.80 BS01 ADP D 1 G17 S18 K22 Q142 G161 D162 K215 K218 E219 G302 G303 S304 L306 F307 L337 G11 S12 K16 Q136 G155 D156 K209 K212 E213 G296 G297 S298 L300 F301 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6znl E 3.80 BS01 ADP E 1 G17 S18 K22 Q142 G161 D162 K218 E219 G302 G303 S304 L306 F307 L337 G11 S12 K16 Q136 G155 D156 K212 E213 G296 G297 S298 L300 F301 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6znl F 3.80 BS01 ADP F 1 G17 V20 K22 Q142 D162 K218 E219 G303 S304 L306 L337 G11 V14 K16 Q136 D156 K212 E213 G297 S298 L300 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6znl G 3.80 BS01 ADP G 1 G17 K22 D162 K215 K218 E219 G302 G303 S304 L306 F307 L337 G11 K16 D156 K209 K212 E213 G296 G297 S298 L300 F301 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6znl H 3.80 BS01 ATP H 1 D11 G13 S14 G15 M16 K18 Q137 G156 D157 R210 K213 E214 G302 M305 Y306 K336 V339 D6 G8 S9 G10 M11 K13 Q132 G151 D152 R205 K208 E209 G297 M300 Y301 K331 V334 Q6QAQ1 AALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 6znl I 3.80 BS01 ADP I 1 G17 K22 Q142 G161 D162 K218 E219 G302 G303 S304 L306 L337 G11 K16 Q136 G155 D156 K212 E213 G296 G297 S298 L300 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6znl J 3.80 BS01 ADP J 1 G21 E22 A23 F24 K26 G142 Y143 H172 E208 K211 V212 G308 T309 M311 N351 G10 E11 A12 F13 K15 G131 Y132 H161 E197 K200 V201 G297 T298 M300 N340 I3LHK5 EKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKKAGMPKPIKVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLLEQCTVDTGAAKEQSLPSVMGSIPEGVLEDIKVRTCFVSDLTRGLKIQAAKFNIDGNTERPSPPPNVDYPLDGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLMQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKTFRIHTPPAKANCVAWLGGAIFGALQDILGSRSVSKEYYNQTGRIPDWCSL 6znl Y 3.80 BS01 ADP J 1 R255 Q262 R201 Q208 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6znl Y 3.80 BS02 ZN Y 1 C30 C33 R37 C287 C29 C32 R36 C233 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6znl Y 3.80 BS03 ZN Y 2 C51 C54 C70 C73 C50 C53 C69 C72 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6znl Y 3.80 BS04 ZN Y 3 C76 C79 C111 C114 C75 C78 C93 C96 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6znm G 4.10 BS01 ADP G 1 G17 K22 D162 K215 K218 E219 G302 G303 S304 L306 F307 L337 G11 K16 D156 K209 K212 E213 G296 G297 S298 L300 F301 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6znm H 4.10 BS01 ATP H 1 D11 G13 S14 G15 M16 K18 Q137 G156 D157 R210 K213 E214 G302 M305 Y306 K336 V339 D6 G8 S9 G10 M11 K13 Q132 G151 D152 R205 K208 E209 G297 M300 Y301 K331 V334 Q6QAQ1 AALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 6znm I 4.10 BS01 ADP I 1 G17 K22 Q142 G161 D162 K218 E219 G302 G303 S304 L306 L337 G11 K16 Q136 G155 D156 K212 E213 G296 G297 S298 L300 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6znm J 4.10 BS01 ADP J 1 G21 E22 A23 F24 K26 G142 Y143 H172 E208 K211 V212 G308 T309 M311 N351 G10 E11 A12 F13 K15 G131 Y132 H161 E197 K200 V201 G297 T298 M300 N340 I3LHK5 EKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKKAGMPKPIKVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLLEQCTVDTGAAKEQSLPSVMGSIPEGVLEDIKVRTCFVSDLTRGLKIQAAKFNIDGNTERPSPPPNVDYPLDGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLMQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKTFRIHTPPAKANCVAWLGGAIFGALQDILGSRSVSKEYYNQTGRIPDWCSL 6znm Y 4.10 BS01 ADP J 1 R255 Q262 R201 Q208 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6znm Y 4.10 BS02 ZN Y 1 C30 C33 R37 C287 C29 C32 R36 C233 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6znm Y 4.10 BS03 ZN Y 2 C51 C54 C70 C73 C50 C53 C69 C72 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6znm Y 4.10 BS04 ZN Y 3 C76 C79 C111 C114 C75 C78 C93 C96 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6znn G 4.50 BS01 ADP G 1 G17 K22 D162 K215 K218 E219 G302 G303 S304 L306 F307 L337 G11 K16 D156 K209 K212 E213 G296 G297 S298 L300 F301 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6znn H 4.50 BS01 ATP H 1 D11 G13 S14 G15 M16 K18 Q137 G156 D157 R210 K213 E214 G302 M305 Y306 K336 V339 D6 G8 S9 G10 M11 K13 Q132 G151 D152 R205 K208 E209 G297 M300 Y301 K331 V334 Q6QAQ1 AALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 6znn I 4.50 BS01 ADP I 1 G17 K22 Q142 G161 D162 K218 E219 G302 G303 S304 L306 L337 G11 K16 Q136 G155 D156 K212 E213 G296 G297 S298 L300 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6znn J 4.50 BS01 ADP J 1 G21 E22 A23 F24 K26 G142 Y143 H172 E208 K211 V212 G308 T309 M311 N351 G10 E11 A12 F13 K15 G131 Y132 H161 E197 K200 V201 G297 T298 M300 N340 I3LHK5 EKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKKAGMPKPIKVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLLEQCTVDTGAAKEQSLPSVMGSIPEGVLEDIKVRTCFVSDLTRGLKIQAAKFNIDGNTERPSPPPNVDYPLDGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLMQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKTFRIHTPPAKANCVAWLGGAIFGALQDILGSRSVSKEYYNQTGRIPDWCSL 6znn Y 4.50 BS01 ADP J 1 R255 Q262 R201 Q208 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6znn Y 4.50 BS02 ZN Y 1 C30 C33 R37 C287 C29 C32 R36 C233 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6znn Y 4.50 BS03 ZN Y 2 C51 C54 C70 C73 C50 C53 C69 C72 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6znn Y 4.50 BS04 ZN Y 3 C76 C79 C111 C114 C75 C78 C93 C96 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6zno G 6.80 BS01 ADP G 1 G17 K22 D162 K215 K218 E219 G302 G303 S304 L306 F307 L337 G11 K16 D156 K209 K212 E213 G296 G297 S298 L300 F301 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6zno H 6.80 BS01 ATP H 1 D11 G13 S14 G15 M16 K18 Q137 G156 D157 R210 K213 E214 G302 M305 Y306 K336 V339 D6 G8 S9 G10 M11 K13 Q132 G151 D152 R205 K208 E209 G297 M300 Y301 K331 V334 Q6QAQ1 AALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 6zno I 6.80 BS01 ADP I 1 G17 K22 Q142 G161 D162 K218 E219 G302 G303 S304 L306 L337 G11 K16 Q136 G155 D156 K212 E213 G296 G297 S298 L300 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6zno J 6.80 BS01 ADP J 1 G21 E22 A23 F24 K26 G142 Y143 H172 E208 K211 V212 G308 T309 M311 N351 G10 E11 A12 F13 K15 G131 Y132 H161 E197 K200 V201 G297 T298 M300 N340 I3LHK5 EKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKKAGMPKPIKVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLLEQCTVDTGAAKEQSLPSVMGSIPEGVLEDIKVRTCFVSDLTRGLKIQAAKFNIDGNTERPSPPPNVDYPLDGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLMQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKTFRIHTPPAKANCVAWLGGAIFGALQDILGSRSVSKEYYNQTGRIPDWCSL 6zno Y 6.80 BS01 ADP J 1 R255 Q262 R201 Q208 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6zno Y 6.80 BS02 ZN Y 1 C30 C33 R37 C287 C29 C32 R36 C233 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6zno Y 6.80 BS03 ZN Y 2 C51 C54 C70 C73 C50 C53 C69 C72 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6zno Y 6.80 BS04 ZN Y 3 C76 C79 C111 C114 C75 C78 C93 C96 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6zo4 G 8.20 BS01 ADP G 1 G17 K22 D162 K215 K218 E219 G302 G303 S304 L306 F307 L337 G11 K16 D156 K209 K212 E213 G296 G297 S298 L300 F301 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6zo4 H 8.20 BS01 ATP H 1 D11 G13 S14 G15 M16 K18 Q137 G156 D157 R210 K213 E214 G302 M305 Y306 K336 V339 D6 G8 S9 G10 M11 K13 Q132 G151 D152 R205 K208 E209 G297 M300 Y301 K331 V334 Q6QAQ1 AALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 6zo4 I 8.20 BS01 ADP I 1 G17 K22 Q142 G161 D162 K218 E219 G302 G303 S304 L306 L337 G11 K16 Q136 G155 D156 K212 E213 G296 G297 S298 L300 L331 F2Z5G5 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF 6zo4 J 8.20 BS01 ADP J 1 G21 E22 A23 F24 K26 G142 Y143 H172 E208 K211 V212 G308 T309 M311 N351 G10 E11 A12 F13 K15 G131 Y132 H161 E197 K200 V201 G297 T298 M300 N340 I3LHK5 EKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKKAGMPKPIKVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLLEQCTVDTGAAKEQSLPSVMGSIPEGVLEDIKVRTCFVSDLTRGLKIQAAKFNIDGNTERPSPPPNVDYPLDGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLMQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKTFRIHTPPAKANCVAWLGGAIFGALQDILGSRSVSKEYYNQTGRIPDWCSL 6zo4 Y 8.20 BS01 ADP J 1 R255 Q262 R201 Q208 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6zo4 Y 8.20 BS02 ZN Y 1 C30 C33 R37 C287 C29 C32 R36 C233 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6zo4 Y 8.20 BS03 ZN Y 2 C51 C54 C70 C73 C50 C53 C69 C72 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6zo4 Y 8.20 BS04 ZN Y 3 C76 C79 C111 C114 C75 C78 C93 C96 A0A4X1TB62 ASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATAYYLACGFCRWTSRDVGMADKSVASGGWQEPDHPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPICASQLYPRHKHLLIKRSLRCRQCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLLECEEGDPDDTNSTAKVSVPPTELVLAGKDAAAEYDELAEPQDFPDDPDVVAFRKANKVGVFIKVTPQREEGDVTVCFKLKHDFKNLAAPIRPVEEADPGAEVSWLTQHVELSLGP 6zok L 2.80 BS01 MG L 1 K98 N100 K97 N99 P62280 ADIQTERAYQKQPTIFQNKKRVLLGETGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAGTK 6zok X 2.80 BS01 MG X 1 P62 N63 P61 N62 P62266 GKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPR 6zok a 2.80 BS01 ZN a 1 C23 C26 C74 C77 C22 C25 C73 C76 P62854 TKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPPRFR 6zsl B 1.94 BS01 ZN B 1 C16 C19 H33 H39 C15 C18 H32 H38 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 VGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPAVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIP 6zsl B 1.94 BS02 ZN B 2 C5 C8 C26 C29 C4 C7 C25 C28 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 VGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPAVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIP 6zsl B 1.94 BS03 ZN B 3 C50 C55 C72 H75 C49 C54 C71 H74 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 VGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPAVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIP 6zsl A 1.94 BS01 ZN A 1 C50 C55 C72 H75 C50 C55 C72 H75 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYQIGEYTFEKDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEI 6zsl A 1.94 BS02 ZN A 2 C16 C19 H33 H39 C16 C19 H33 H39 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYQIGEYTFEKDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEI 6zsl A 1.94 BS03 ZN A 3 C5 C8 C26 C29 C5 C8 C26 C29 3.4.19.12,3.4.22.-,3.4.22.69,2.7.7.48,3.6.4.12,3.6.4.13,3.1.13.- P0DTD1 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYQIGEYTFEKDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEI 7c38 A 1.20 BS01 FUC A 1 R97 E109 C111 Y122 G124 A125 L149 F165 W171 R96 E108 C110 Y121 G123 A124 L148 F164 W170 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVAA 7c38 A 1.20 BS02 FUL A 1 R150 E162 A175 P200 W218 W223 R149 E161 A174 P199 W217 W222 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVAA 7c38 A 1.20 BS03 FUL A 2 R192 R203 E215 R224 G226 Q227 F228 N268 W272 R191 R202 E214 R223 G225 Q226 F227 N267 W271 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVAA 7c38 A 1.20 BS04 FUC A 2 R192 R203 E215 G226 Q227 F228 N268 W272 R191 R202 E214 G225 Q226 F227 N267 W271 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVAA 7c38 B 1.20 BS01 FUC B 1 R97 E109 C111 Y122 G124 A125 L149 F165 W171 R96 E108 C110 Y121 G123 A124 L148 F164 W170 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVA 7c38 B 1.20 BS02 FUL B 1 R150 E162 A175 P200 W218 W223 R149 E161 A174 P199 W217 W222 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVA 7c38 B 1.20 BS03 FUL B 2 R192 R203 E215 R224 G226 Q227 F228 N268 W272 R191 R202 E214 R223 G225 Q226 F227 N267 W271 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVA 7c38 B 1.20 BS04 FUC B 2 R192 R203 E215 Q227 F228 N268 W272 R191 R202 E214 Q226 F227 N267 W271 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVA 7c39 A 1.85 BS01 MFU A 1 R97 E109 G124 A125 L149 F165 W171 R96 E108 G123 A124 L148 F164 W170 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVAAAL 7c39 A 1.85 BS02 MFU A 2 R192 R203 E215 V217 R224 G226 Q227 F228 N268 W272 R191 R202 E214 V216 R223 G225 Q226 F227 N267 W271 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVAAAL 7c39 A 1.85 BS03 MFU A 3 R150 E162 A175 P200 W218 W223 R149 E161 A174 P199 W217 W222 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVAAAL 7c39 B 1.85 BS01 MFU B 1 R192 R203 E215 G226 Q227 F228 N268 W272 R191 R202 E214 G225 Q226 F227 N267 W271 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVAA 7c39 B 1.85 BS02 MFU B 2 R97 E109 C111 Y122 G124 A125 L149 F165 W171 R96 E108 C110 Y121 G123 A124 L148 F164 W170 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVAA 7c39 B 1.85 BS03 MFU B 3 R150 E162 A175 P200 W218 W223 R149 E161 A174 P199 W217 W222 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVAA 7c3d A 1.60 BS01 SEJ A 1 R97 E109 C111 Y122 G124 A125 L149 F165 W171 R96 E108 C110 Y121 G123 A124 L148 F164 W170 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVA 7c3d A 1.60 BS02 64K A 1 R203 E215 R224 Q227 F228 W272 R202 E214 R223 Q226 F227 W271 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVA 7c3d B 1.60 BS01 SEJ B 1 R97 E109 C111 Y122 A125 L149 F165 W171 R96 E108 C110 Y121 A124 L148 F164 W170 G1XA82 PVEFPKSLRASSHSSEGGTTKEEDIYGYELLYRSAFASYIAPTGAWNLVWFQAADGSIKQARWYGEWVISTVLAPGKALQGTPLTALLWGPQDTVRLYYLSPQFELQEWCWDTKNGADNKYDGALNAAKVKVAPYSKLGAVSFGGANLRVYYQGTNNKLEEYTFGGGQGWKKGATLPGDPLPGTYISFVNRNKWDANPPSIRGYFQTVTGSLAEQVWETGGWRIGQFVIPAAPFLTPISATVSPEKDFPKIHVYWLSVESTIIESVNWHGWKAPKQIDNISVVKADISATSFTRDDGTVDVRIYGTAQLNVLFERIFRYGVWEEKIHSISVGKEIPIEVVGVAAAL 7c61 A 3.00 BS01 ERM A 1 W125 D129 I130 C133 T134 C199 V200 V201 W367 F370 F371 F391 D392 T395 Y399 W88 D92 I93 C96 T97 C154 V155 V156 W309 F312 F313 F331 D332 T335 Y339 P28222 32669569 YIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLRKATKTLGIILGAFIVCWLPFFIISLVMPICACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHK 7c6a A 3.40 BS01 III B 1 S36 P39 W100 Y103 Y104 Y108 L124 T125 M128 R182 I187 E188 Y189 C195 I196 M197 Y204 K215 D279 W283 D297 L300 P301 I304 F308 S2 P5 W66 Y69 Y70 Y74 L90 T91 M94 R143 I148 E149 Y150 C156 I157 M158 Y165 K176 D329 W333 D347 L350 P351 I354 F358 P50052 32669569 CSQKPSDKHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLVLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIWFITCMSVDRYQSVIYPFNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKAMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGN 7c7p A 1.74 BS01 SV6 A 1 T26 H41 M49 N142 G143 S144 C145 H164 M165 E166 L167 P168 D187 R188 Q189 Q192 T26 H41 M49 N142 G143 S144 C145 H164 M165 E166 L167 P168 D187 R188 Q189 Q192 3.4.22.69 P0DTD1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCS 7c7p B 1.74 BS01 FK3 B 1 T25 T26 H41 G143 S144 C145 H164 M165 D187 R188 Q189 T25 T26 H41 G137 S138 C139 H158 M159 D181 R182 Q183 3.4.22.69 P0DTD1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 7cgq A 2.21 BS01 NAP A 1 G13 K14 I15 S37 R38 H39 C67 A68 P69 V72 R73 Q76 E90 K91 H119 Q156 W158 D169 Y266 G10 K11 I12 S34 R35 H36 C64 A65 P66 V69 R70 Q73 E87 K88 H116 Q153 W155 D166 Y263 1.1.1.376,1.1.1.120,1.1.1.48 Q53TZ2 QVSLGVVGIGKIARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLAAERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFATWHSRCASAVEPAREWLATRAIRAVQVRWKADVRRWHPGQQWIWEPGGLGVFDPGINALSIVTRILPRELVLREATLIVPSDVQTPIAAELDCADTDGVPVRAEFDWRHGPVEQWEIAVDTADGVLAISRGGAQLSIAGEPVELGPEREYPALYAHFHALIARGESDVDVRPLRLVADAFLFGRRVQTDAFGR 7cgq A 2.21 BS02 ARA A 1 K91 H119 W152 H153 D169 P170 N173 K88 H116 W149 H150 D166 P167 N170 1.1.1.376,1.1.1.120,1.1.1.48 Q53TZ2 QVSLGVVGIGKIARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLAAERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFATWHSRCASAVEPAREWLATRAIRAVQVRWKADVRRWHPGQQWIWEPGGLGVFDPGINALSIVTRILPRELVLREATLIVPSDVQTPIAAELDCADTDGVPVRAEFDWRHGPVEQWEIAVDTADGVLAISRGGAQLSIAGEPVELGPEREYPALYAHFHALIARGESDVDVRPLRLVADAFLFGRRVQTDAFGR 7cgq B 2.21 BS01 NAP B 1 G13 K14 I15 S37 R38 H39 A68 P69 V72 G10 K11 I12 S34 R35 H36 A65 P66 V69 1.1.1.376,1.1.1.120,1.1.1.48 Q53TZ2 QVSLGVVGIGKIARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLAAERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFATWHSRCASAVEPAREWLATRAIRAVQVRWKADVRRQQWIWEPGGLGVFDPGINALSIVTRILPRELVLREATLIVPSDVQTPIAAELDCADTDGVPVRAEFDWRHGPVEQWEIAVDTADGVLAISRGGAQLSIAGEPVELGPEREYPALYAHFHALIARGESDVDVRPLRLVADAFLFGRRVQTDAF 7cgq C 2.21 BS01 NAP C 1 G13 S37 R38 H39 A68 P69 V72 G11 S35 R36 H37 A66 P67 V70 1.1.1.376,1.1.1.120,1.1.1.48 Q53TZ2 DQVSLGVVGIGKIARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLAAERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFATWHSRCASAVEPAREWLATRAIRAVQVRWKADVRRWHPGQQWIWEPGGLGVFDPGINALSIVTRILPRELVLREATLIVPSDVQTPIAAELDCADTDGVPVRAEFDWRHGPVEQWEIAVDTADGVLAISRGGAQLSIAGEPVELGPEREYPALYAHFHALIARGESDVDVRPLRLVADAFLFGRRVQTDAFG 7cgq D 2.21 BS01 NAP D 1 G13 K14 I15 S37 R38 H39 C67 A68 P69 P70 V72 R73 E90 K91 H119 H153 Q156 W158 D169 Y266 G10 K11 I12 S34 R35 H36 C64 A65 P66 P67 V69 R70 E87 K88 H116 H150 Q153 W155 D166 Y263 1.1.1.376,1.1.1.120,1.1.1.48 Q53TZ2 QVSLGVVGIGKIARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLAAERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFATWHSRCASAVEPAREWLATRAIRAVQVRWKADVRRWHPGQQWIWEPGGLGVFDPGINALSIVTRILPRELVLREATLIVPSDVQTPIAAELDCADTDGVPVRAEFDWRHGPVEQWEIAVDTADGVLAISRGGAQLSIAGEPVELGPEREYPALYAHFHALIARGESDVDVRPLRLVADAFLFGRRVQTDAFG 7cgr A 2.09 BS01 NAP A 1 G13 K14 I15 S37 R38 H39 C67 A68 P69 V72 R73 E90 K91 H119 W152 H153 Q156 W158 D169 Y266 G10 K11 I12 S34 R35 H36 C64 A65 P66 V69 R70 E87 K88 H116 W149 H150 Q153 W155 D166 Y263 1.1.1.376,1.1.1.120,1.1.1.48 Q53TZ2 QVSLGVVGIGKIARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLAAERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFATWHSRCASAVEPAREWLATRAIRAVQVRWKADVRRWHPGQQWIWEPGGLGVFDPGINALSIVTRILPRELVLREATLIVPSDVQTPIAAELDCADTDGVPVRAEFDWRHGPVEQWEIAVDTADGVLAISRGGAQLSIAGEPVELGPEREYPALYAHFHALIARGESDVDVRPLRLVADAFLFGRRVQTDAFGR 7cgr A 2.09 BS02 GOL A 1 K91 H119 W152 H153 D169 P170 N173 K88 H116 W149 H150 D166 P167 N170 1.1.1.376,1.1.1.120,1.1.1.48 Q53TZ2 QVSLGVVGIGKIARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLAAERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFATWHSRCASAVEPAREWLATRAIRAVQVRWKADVRRWHPGQQWIWEPGGLGVFDPGINALSIVTRILPRELVLREATLIVPSDVQTPIAAELDCADTDGVPVRAEFDWRHGPVEQWEIAVDTADGVLAISRGGAQLSIAGEPVELGPEREYPALYAHFHALIARGESDVDVRPLRLVADAFLFGRRVQTDAFGR 7cgr A 2.09 BS03 GOL A 2 E27 A271 H274 A275 E24 A268 H271 A272 1.1.1.376,1.1.1.120,1.1.1.48 Q53TZ2 QVSLGVVGIGKIARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLAAERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFATWHSRCASAVEPAREWLATRAIRAVQVRWKADVRRWHPGQQWIWEPGGLGVFDPGINALSIVTRILPRELVLREATLIVPSDVQTPIAAELDCADTDGVPVRAEFDWRHGPVEQWEIAVDTADGVLAISRGGAQLSIAGEPVELGPEREYPALYAHFHALIARGESDVDVRPLRLVADAFLFGRRVQTDAFGR 7cgr B 2.09 BS01 NAP B 1 G11 G13 S37 R38 H39 A68 P69 V72 G8 G10 S34 R35 H36 A65 P66 V69 1.1.1.376,1.1.1.120,1.1.1.48 Q53TZ2 QVSLGVVGIGKIARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLAAERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFATWHSRCASAVEPAREWLATRAIRAVQVRWKADVRRQWIWEPGGLGVFDPGINALSIVTRILPRELVLREATLIVPSDVQTPIAAELDCADTDGVPVRAEFDWRHGPVEQWEIAVDTADGVLAISRGGAQLSIAGEPVELGPEREYPALYAHFHALIARGESDVDVRPLRLVADAFLFGRRVQTDAF 7cgr C 2.09 BS01 NAP C 1 G11 G13 S37 R38 H39 A68 P69 V72 W158 G9 G11 S35 R36 H37 A66 P67 V70 W156 1.1.1.376,1.1.1.120,1.1.1.48 Q53TZ2 DQVSLGVVGIGKIARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLAAERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFATWHSRCASAVEPAREWLATRAIRAVQVRWKADVRRWHPGQQWIWEPGGLGVFDPGINALSIVTRILPRELVLREATLIVPSDVQTPIAAELDCADTDGVPVRAEFDWRHGPVEQWEIAVDTADGVLAISRGGAQLSIAGEPVELGPEREYPALYAHFHALIARGESDVDVRPLRLVADAFLFGRRVQTDAFG 7cgr D 2.09 BS01 NAP D 1 G11 G13 K14 I15 S37 R38 H39 C67 A68 P69 P70 V72 R73 Q76 E90 K91 H119 Q156 W158 D169 Y266 G8 G10 K11 I12 S34 R35 H36 C64 A65 P66 P67 V69 R70 Q73 E87 K88 H116 Q153 W155 D166 Y263 1.1.1.376,1.1.1.120,1.1.1.48 Q53TZ2 QVSLGVVGIGKIARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLAAERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFATWHSRCASAVEPAREWLATRAIRAVQVRWKADVRRWHPGQQWIWEPGGLGVFDPGINALSIVTRILPRELVLREATLIVPSDVQTPIAAELDCADTDGVPVRAEFDWRHGPVEQWEIAVDTADGVLAISRGGAQLSIAGEPVELGPEREYPALYAHFHALIARGESDVDVRPLRLVADAFLFGRRVQTDAFG 7cgr D 2.09 BS02 GOL D 1 K91 H119 H153 N173 K88 H116 H150 N170 1.1.1.376,1.1.1.120,1.1.1.48 Q53TZ2 QVSLGVVGIGKIARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLAAERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFATWHSRCASAVEPAREWLATRAIRAVQVRWKADVRRWHPGQQWIWEPGGLGVFDPGINALSIVTRILPRELVLREATLIVPSDVQTPIAAELDCADTDGVPVRAEFDWRHGPVEQWEIAVDTADGVLAISRGGAQLSIAGEPVELGPEREYPALYAHFHALIARGESDVDVRPLRLVADAFLFGRRVQTDAFG 7ckj A 1.50 BS01 C5P A 1 S11 K15 S33 G34 Y37 R38 V97 A101 R107 G125 R126 D127 M128 S11 K15 S33 G34 Y37 R38 V97 A101 R107 G125 R126 D127 M128 2.7.4.25 Q5SL35 32469932 MRGIVTIDGPSASGKSSVARRVAAALGVPYLSSGLLYRAAAFLALRAGVDPGDEEGLLALLEGLGVRLLAQAEGNRVLADGEDLTSFLHTPEVDRVVSAVARLPGVRAWVNRRLKEVPPPFVAEGRDMGTAVFPEAAHKFYLTASPEVRAWRRARERPQAYEEVLRDLLRRDERDQSAPAPDALVLDTGGMTLDEVVAWVLAHIRR