6e37 A 2.53 BS01 III B 1 H496 N557 H558 P559 Y632 T633 K634 Q839 V895 A896 P897 H183 N244 H245 P246 Y319 T320 K321 Q504 V560 A561 P562 2.4.1.255 O15294 31626249 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFHIYDNRIVLNGIDLKAFLDSLPDVKIVNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMI 6iat A 3.30 BS01 III G 1 L63 D65 F131 L133 N134 T138 R139 L145 A148 T149 N150 A152 L153 G154 Y156 P363 H365 V372 L60 D62 F128 L130 N131 T135 R136 L142 A145 T146 N147 A149 L150 G151 Y153 P360 H362 V369 Q859I3 31663016 QSTKNETALLVAKSAKSALQDFNHDYSKSWTFGDKWDNSNTMFETFVNKYLFPKINETLLIDIALGNRFNWLAKEQDFIGQYSEEYVIMDTVPINMDLSKNEELMLKRNYPRMATKLYGNGIVKKQKFTLNNNDTRFNFQTLADATNYALGVYKKKISDINVLEEKEMRAMLVDYSLNQLSETNVRKATSKEDLASKVFEAILNLQNNSAKYNEVHRASGGAIGQYTTVSKLKDIVILTTDSLKSYLLDTKIANTFQIAGIDFTDHVISFDDLGGVFKVTKEFKLQNQDSIDFLRAYGDYQSQLGDTIPVGAVFTYDVSKLKEFTGNVEEIKPKSDLYAFILDINSIKYKRYTKGMLKPPFHNPEFDEVTHWIHYYSFKAISPFFNKILITD 6iat D 3.30 BS01 III G 1 A67 L68 N70 N73 E78 Y156 I160 S161 N164 R354 Y355 T356 K357 G358 M359 A64 L65 N67 N70 E75 Y153 I157 S158 N161 R351 Y352 T353 K354 G355 M356 Q859I3 31663016 QSTKNETALLVAKSAKSALQDFNHDYSKSWTFGDKWDNSNTMFETFVNKYLFPKINETLLIDIALGNRFNWLAKEQDFIGQYSEEYVIMDTVPINMDLSKNEELMLKRNYPRMATKLYGNGIVKKQKFTLNNNDTRFNFQTLADATNYALGVYKKKISDINVLEEKEMRAMLVDYSLNQLSETNVRKATSKEDLASKVFEAILNLQNNSAKYNEVHRASGGAIGQYTTVSKLKDIVILTTDSLKSYLLDTKIANTFQIAGIDFTDHVISFDDLGGVFKVTKEFKLQNQDSIDFLRAYGDYQSQLGDTIPVGAVFTYDVSKLKEFTGNVEEIKPKSDLYAFILDINSIKYKRYTKGMLKPPFHNPEFDEVTHWIHYYSFKAISPFFNKILITDQ 6iat F 3.30 BS01 III G 1 T58 G59 T54 G55 Q859I2 31663016 MYEGNNMRSMMGTSYEDSRLNKRTELNENMSIDTNKSEDSYGVQIHSLSKQSFTG 6iaw B 3.80 BS01 III Y 1 F259 Q260 A262 F249 Q250 A252 Q859I3 31663016 ALLVAKSAKSALQDFNHDYSKSWTFGDKWDNSNTMFETFVNKYLFPKINETLLIDIALGNRFNWLAKEQDFIGQYSEEYVIMDTVPINMDLSKNEELMLKRNYPRMATKLYGNGIVKKQKFTLNNNDTRFNFQTLADATNYALGVYKKKISDINVLEEKEMRAMLVDYSLNQLSETNVRKATSKEDLASKVFEAILNLQNNSAKYNEVHRASGGAIGQYTTVSKLKDIVILTTDSLKSYLLDTKIANTFQIAGIDFTDHVISFDDLGGVFKVTKEFKLQNQDSIDFLRAYGDYQSQLGDTIPVGAVFTYDVSKLKEFTGNVEEIKPKSDLYAFILDINSIKYKRYTKGMLKPPFHNPEFDEVTHWIHYYSFKAISPFFNKILITDQ 6iaw I 3.80 BS01 III Y 1 Y41 V43 Y41 V43 Q859I2 31663016 MYEGNNMRSMMGTSYEDSRLNKRTELNENMSIDTNKSEDSYGVQIHSLSKQSFTG 6iaw D 3.80 BS01 III Z 1 D39 I45 H46 S47 D15 I21 H22 S23 Q859I2 31663016 ELNENMSIDTNKSEDSYGVQIHSLSKQSFT 6iaw Q 3.80 BS01 III Y 1 Y41 G42 V43 Y41 G42 V43 Q859I2 31663016 MYEGNNMRSMMGTSYEDSRLNKRTELNENMSIDTNKSEDSYGVQIHSLSKQSFTG 6ib1 D 3.50 BS01 III G 1 L133 N134 T138 R139 L145 A148 T149 N150 A152 L153 Y156 P363 H365 V372 H374 L130 N131 T135 R136 L142 A145 T146 N147 A149 L150 Y153 P360 H362 V369 H371 Q859I3 31663016 QSTKNETALLVAKSAKSALQDFNHDYSKSWTFGDKWDNSNTMFETFVNKYLFPKINETLLIDIALGNRFNWLAKEQDFIGQYSEEYVIMDTVPINMDLSKNEELMLKRNYPRMATKLYGNGIVKKQKFTLNNNDTRFNFQTLADATNYALGVYKKKISDINVLEEKEMRAMLVDYSLNQLSETNVRKATSKEDLASKVFEAILNLQNNSAKYNEVHRASGGAIGQYTTVSKLKDIVILTTDSLKSYLLDTKIANTFQIAGIDFTDHVISFDDLGGVFKVTKEFKLQNQDSIDFLRAYGDYQSQLGDTIPVGAVFTYDVSKLKEFTGNVEEIKPKSDLYAFILDINSIKYKRYTKGMLKPPFHNPEFDEVTHWIHYYSFKAISPFFNKILITD 6ib1 A 3.50 BS01 III G 1 L68 N70 R71 N73 W74 E78 Y156 I160 S161 N164 R354 Y355 T356 K357 G358 M359 L360 L65 N67 R68 N70 W71 E75 Y153 I157 S158 N161 R351 Y352 T353 K354 G355 M356 L357 Q859I3 31663016 QSTKNETALLVAKSAKSALQDFNHDYSKSWTFGDKWDNSNTMFETFVNKYLFPKINETLLIDIALGNRFNWLAKEQDFIGQYSEEYVIMDTVPINMDLSKNEELMLKRNYPRMATKLYGNGIVKKQKFTLNNNDTRFNFQTLADATNYALGVYKKKISDINVLEEKEMRAMLVDYSLNQLSETNVRKATSKEDLASKVFEAILNLQNNSAKYNEVHRASGGAIGQYTTVSKLKDIVILTTDSLKSYLLDTKIANTFQIAGIDFTDHVISFDDLGGVFKVTKEFKLQNQDSIDFLRAYGDYQSQLGDTIPVGAVFTYDVSKLKEFTGNVEEIKPKSDLYAFILDINSIKYKRYTKGMLKPPFHNPEFDEVTHWIHYYSFKAISPFFNKILITDQ 6iov A 2.35 BS01 ARG A 1 L123 W141 W147 R152 W154 Y170 D172 S173 A174 F199 D201 L59 W77 W83 R88 W90 Y106 D108 S109 A110 F135 D137 A0A085T373 SVSDSVDEIVDGVSKTTAEVINGRKSIAQYATSLIESNPEPDNVRTIISQPLIKNTFLLVGFGLEKDGSNINNDPSWNPGPTWDPRVRPWYKDAKNAGKLVITAPYADSASGEILVSVATPVKDSATGQFLGSIFYDVSLAELAELVNEVKLFDAGYVFIVSEDGTTIAHPKKEFNGKPMSEFLGESKINVDTHQVIINGKPYAVSFSDVEGEDWYVGVVIDEE 6iqj B 1.92 BS01 III D 1 M1 S2 W3 Y6 W33 Y125 L126 S129 L131 M1 S2 W3 Y6 W33 Y125 L126 S129 L131 Q42418 31653702 MSWQSYVDDHLMCEVEGNHLTHAAIFGQDGSVWAQSSAFPQLKPAEIAGINKDFEEAGHLAPTGLFLGGEKYMVVQGEAGAVIRGKKGPGGVTIKKTTQALVFGIYDEPMTGGQCNLVVERLGDYLIESGL 6iqj A 1.92 BS01 III C 1 M1 W3 Y6 H10 W33 R121 L122 Y125 S129 L131 M1 W3 Y6 H10 W33 R121 L122 Y125 S129 L131 Q42418 31653702 MSWQSYVDDHLMCEVEGNHLTHAAIFGQDGSVWAQSSAFPQLKPAEIAGINKDFEEAGHLAPTGLFLGGEKYMVVQGEAGAVIRGKKGPGGVTIKKTTQALVFGIYDEPMTGGQCNLVVERLGDYLIESGL 6iug A 3.90 BS01 ADP A 1 G15 T16 G17 M18 K20 G158 D159 R212 K215 E216 G304 T305 M307 F308 K338 G9 T10 G11 M12 K14 G152 D153 R206 K209 E210 G298 T299 M301 F302 K332 B6TQ08 31628168 IQPLVCDNGTGMVKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIVSNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDMKEKLAYIALDYDQEMETAKTSSSVEKSYELPDGQVITIGAERFRCPEVLFQPSFIGMEAAGIHETTYNSIMKCDVDIRKDLYGNIVLSGGTTMFPGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQMWIAKAEYDESGPSIVHRKCF 6iup A 2.00 BS01 AX0 A 1 L473 G474 C477 V481 A501 K503 E520 V550 E551 C552 A553 G556 L619 D630 L22 G23 C26 V30 A50 K52 E67 V97 E98 C99 A100 G103 L157 D168 2.7.10.1 P22455 31335138 LDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDEVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAV 6ivj A 2.77 BS03 CL A 1 T95 K188 E191 T75 K168 E171 W9BH30 31263784 LSKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQ 6ivj A 2.77 BS04 CL A 2 H108 H111 R112 H88 H91 R92 W9BH30 31263784 LSKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQ 6ivj B 2.77 BS02 ZN B 2 H108 H111 R112 H290 H87 H90 R91 H269 W9BH30 31263784 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQHP 6ivj C 2.77 BS04 CL C 2 R101 H108 H111 T287 R79 H86 H89 T265 W9BH30 31263784 KIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQHP 6ivj D 2.77 BS04 CL D 2 R101 H108 H111 R80 H87 H90 W9BH30 31263784 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQ 6ivj E 2.77 BS05 CL E 2 H108 H111 T287 H85 H88 T264 W9BH30 31263784 IIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQHPLP 6ivk D 2.65 BS04 CL D 1 I91 T95 K188 E191 I70 T74 K167 E170 W9BH30 31263784 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAAKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQ 6ivm A 2.95 BS04 CL A 2 H108 R112 Q289 H88 R92 Q269 W9BH30 31263784 LSKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLAEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQH 6ivm A 2.95 BS06 LEU B 1 N166 Q170 N146 Q150 W9BH30 31263784 LSKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLAEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQH 6ivm E 2.95 BS04 CL E 2 H108 H111 R112 T287 H85 H88 R89 T264 W9BH30 31263784 IIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLAEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQHPLPE 6ivm E 2.95 BS06 CL E 1 A92 T95 K188 E191 A69 T72 K165 E168 W9BH30 31263784 IIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLAEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQHPLPE 6ivn B 3.10 BS03 CL B 2 H108 H111 G288 H87 H90 G267 W9BH30 31263784 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFATAANDLPLNAMCNTIERNLLDMTGQHP 6ivn C 3.10 BS04 ZN C 2 E46 H51 E24 H29 W9BH30 31263784 KIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFATAANDLPLNAMCNTIERNLLDMTGQHP 6ivn E 3.10 BS01 GLU E 1 L292 P293 L271 P272 W9BH30 31263784 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFATAANDLPLNAMCNTIERNLLDMTGQHPLP 6ivo D 2.45 BS04 CL D 2 H108 H111 R112 T287 G288 H87 H90 R91 T266 G267 W9BH30 31263784 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVAFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQHPLPE 6ivp B 3.80 BS03 CL B 1 H108 H111 R112 G288 H87 H90 R91 G267 W9BH30 31263784 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDAFGTAANDLPLNAMCNTIERNLLDMTGQH 6ivp C 3.80 BS02 CL C 1 I91 A92 T95 K188 E191 I69 A70 T73 K166 E169 W9BH30 31263784 KIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDAFGTAANDLPLNAMCNTIERNLLDMTGQHP 6ivp D 3.80 BS04 CL D 2 R101 H108 T287 R80 H87 T266 W9BH30 31263784 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDAFGTAANDLPLNAMCNTIERNLLDMTGQ 6ivp D 3.80 BS05 CL D 3 H111 R112 T287 H90 R91 T266 W9BH30 31263784 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDAFGTAANDLPLNAMCNTIERNLLDMTGQ 6ivq A 2.65 BS04 CL A 2 H108 H111 T287 Q289 H88 H91 T267 Q269 W9BH30 31263784 LSKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQH 6ivr B 2.80 BS02 ZN B 1 I39 H235 I18 H214 W9BH30 31263784 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQHP 6j0d A 1.90 BS01 ZN A 1 C37 C40 H53 H58 C28 C31 H44 H49 Q653D5 31278262 KVFCYYCDREFDDEKILVQHQKAKHFKCHVCHKKLSTAGGMAIHVLQVHKESVTKVPNAKPERESTEIEIFGMQGIPPDVLAAHYGE 6j0p A 1.79 BS01 COA A 1 N11 S12 Q15 R131 S194 Q195 K256 N306 A308 N343 G344 M345 L347 N348 G391 A392 G393 N413 Y416 I419 L422 F539 R542 N13 S14 Q17 R133 S196 Q197 K258 N308 A310 N345 G346 M347 L349 N350 G393 A394 G395 N415 Y418 I421 L424 F541 R544 O67224 31646188 SHMRILFLSYRFNSLSQRLYCELTEREHEVSVELDVHPDLTVEAAELYKPDLIIAPFLKRKIPQEVWKKYKTLIIHPGPPGDRGPNALDWAIMKGERIWGVTLLEASEEYDAGDVWAYRTFPMRFARKASIYRNEVTEGVVECVLEALENFERGDFKPTPQKEHWWNPKMEQELRRVDWEQDDTKTVLRKVYASDSQPGASSKVLGKEVLLFNAYPEEELKGKPGEVLALRDEAVCIGTRDGAVWITHMRERKKESIKLPSARVLGEFLKGVKEDPIKPWEKVDFKTYREILYEEEDGIGFIHFNFYNGAMSTEQCYRLLETIKYAKKRPVKAIVLLGSEDFFSNGMNLNTIENAESPADESWRNINAIDDVCEEILKTPDKLTVAGMQGNAGAGGVFLALTCDLVFAREGVVLNPHYKNIGNLYGSEFWTYTLPKRVGWEKGKEVMENRMPISSKKAFEIGLIDGVFGKTPKEFRQRLKERIKNFINSKDFYEFIEKKKKERTSGEWLEEIQKCREHELEKMKLNFYGFDTSYHIARYYFVRRKPHFRTPPYLAIHRRLKFSL 6j0p B 1.79 BS01 COA B 1 F10 N11 S12 Q15 R131 S194 Q195 K256 N306 A308 N343 G344 M345 N346 L347 N348 G391 A392 G393 N413 Y416 N418 I419 F539 R547 F12 N13 S14 Q17 R133 S196 Q197 K258 N308 A310 N345 G346 M347 N348 L349 N350 G393 A394 G395 N415 Y418 N420 I421 F541 R549 O67224 31646188 SHMRILFLSYRFNSLSQRLYCELTEREHEVSVELDVHPDLTVEAAELYKPDLIIAPFLKRKIPQEVWKKYKTLIIHPGPPGDRGPNALDWAIMKGERIWGVTLLEASEEYDAGDVWAYRTFPMRFARKASIYRNEVTEGVVECVLEALENFERGDFKPTPQKEHWWNPKMEQELRRVDWEQDDTKTVLRKVYASDSQPGASSKVLGKEVLLFNAYPEEELKGKPGEVLALRDEAVCIGTRDGAVWITHMRERKKESIKLPSARVLGEFLKGVKEDPIKPWEKVDFKTYREILYEEEDGIGFIHFNFYNGAMSTEQCYRLLETIKYAKKRPVKAIVLLGSEDFFSNGMNLNTIENAESPADESWRNINAIDDVCEEILKTPDKLTVAGMQGNAGAGGVFLALTCDLVFAREGVVLNPHYKNIGNLYGSEFWTYTLPKRVGWEKGKEVMENRMPISSKKAFEIGLIDGVFGKTPKEFRQRLKERIKNFINSKDFYEFIEKKKKERTSGEWLEEIQKCREHELEKMKLNFYGFDTSYHIARYYFVRRKPHFRTPPYLAIHRRLKFS 6j15 D 2.60 BS01 FUC D 1 E61 F63 F82 Q99 E34 F36 F50 Q58 Q15116 30952089 DGIQWNPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMTDKLAAFPCRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRAELRVTER 6j1f A 2.10 BS02 THG A 1 L56 K57 R58 K59 I60 W65 I72 G82 P83 S105 Y108 D109 K167 L58 K59 R60 K61 I62 W67 I74 G84 P85 S107 Y110 D111 K169 O67224 31646188 SHMRILFLSYRFNSLSQRLYCELTEREHEVSVELDVHPDLTVEAAELYKPDLIIAPFLKRKIPQEVWKKYKTLIIHPGPPGDRGPNALDWAIMKGERIWGVTLLEASEEYDAGDVWAYRTFPMRFARKASIYRNEVTEGVVECVLEALENFERGDFKPTPQKEHWWNPKMEQELRRVDWEQDDTKTVLRKVYASDSQPGASSKVLGKEVLLFNAYPEEELKGKPGEVLALRDEAVCIGTRDGAVWITHMRERKKESIKLPSARVLGEFLKGVKEDPIKPWEKVDFKTYREILYEEEDGIGFIHFNFYNGAMSTEQCYRLLETIKYAKKRPVKAIVLLGSEDFFSNGMNLNTIENAESPADESWRNINAIDDVCEEILKTPDKLTVAGMQGNAGAGGVFLALTCDLVFAREGVVLNPHYKNIGNLYGSEFWTYTLPKRVGWEKGKEVMENRMPISSKKAFEIGLIDGVFGKTPKEFRQRLKERIKNFINSKDFYEFIEKKKKERTSGEWLEEIQKCREHELEKMKLNFYGFDTSYHIARYYFVRRKPHFRTPPYLAIHRRLKFSL 6j1g A 2.50 BS01 COA A 1 N11 S12 S194 Q195 K256 N306 A308 N343 G344 M345 L347 N348 G391 A392 G393 N413 Y416 I419 F539 N13 S14 S196 Q197 K258 N308 A310 N345 G346 M347 L349 N350 G393 A394 G395 N415 Y418 I421 F541 O67224 31646188 SHMRILFLSYAFNSLSARLYCELTEREHEVSVELDVHPDLTVEAAELYKPDLIIAPFLKRKIPQEVWKKYKTLIIHPGPPGDRGPNALDWAIMKGERIWGVTLLEASEEYDAGDVWAYRTFPMRFARKASIYANEVTEGVVECVLEALENFERGDFKPTPQKEHWWNPKMEQELRRVDWEQDDTKTVLRKVYASDSQPGASSKVLGKEVLLFNAYPEEELKGKPGEVLALRDEAVCIGTRDGAVWITHMRERKKESIKLPSARVLGEFLKGVKEDPIKPWEKVDFKTYREILYEEEDGIGFIHFNFYNGAMSTEQCYRLLETIKYAKKRPVKAIVLLGSEDFFSNGMNLNTIENAESPADESWRNINAIDDVCEEILKTPDKLTVAGMQGNAGAGGVFLALTCDLVFAREGVVLNPHYKNIGNLYGSEFWTYTLPKRVGWEKGKEVMENRMPISSKKAFEIGLIDGVFGKTPKEFRQRLKERIKNFINSKDFYEFIEKKKKERTSGEWLEEIQKCREHELEKMKLNFYGFDTSYHIARYYFVRA 6j1i A 2.29 BS01 COA A 1 N11 S12 F55 K126 Y130 R131 S194 Q195 K256 N306 A308 N343 M345 L347 N348 F539 N13 S14 F57 K128 Y132 R133 S196 Q197 K258 N308 A310 N345 M347 L349 N350 F541 O67224 31646188 SHMRILFLSYRFNSLSQRLYCELTEREHEVSVELDVHPDLTVEAAELYKPDLIIAPFLKRKIPQEVWKKYKTLIIHPGPPGDRGPNALDWAIMKGERIWGVTLLEASEEYDAGDVWAYRTFPMRFARKASIYRNEVTEGVVECVLEALENFERGDFKPTPQKEHWWNPKMEQELRRVDWEQDDTKTVLRKVYASDSQPGASSKVLGKEVLLFNAYPEEELKGKPGEVLALRDEAVCIGTRDGAVWITHMRERKKESIKLPSARVLGEFLKGVKEDPIKPWEKVDFKTYREILYEEEDGIGFIHFNFYNGAMSTEQCYRLLETIKYAKKRPVKAIVLLGSEDFFSNGMNLNTIENAESPADESWRNINAIDDVCEEILKTPDKLTVAGMQGNAGFGGVFLALTCDLVFAREGVVLNPHYKNFGNLYGSEFWTYTLPKRVGWEKGKEVMENRMPISSKKAFEIGLIDGVFGKTPKEFRQRLKERIKNFINSKDFYEFIEKKKKERTSGEWLEEIQKCREHELEKMKLNFYGFDTSYHIARYYFVRRKPHFRTPPYLAIHRRLKFS 6j1j A 2.00 BS01 COA A 1 R9 N11 S12 A53 F55 L56 I72 I73 P75 K126 Y130 R131 S194 Q195 K256 N306 A308 N343 M345 N346 L347 N348 F539 R11 N13 S14 A55 F57 L58 I74 I75 P77 K128 Y132 R133 S196 Q197 K258 N308 A310 N345 M347 N348 L349 N350 F541 O67224 31646188 SHMRILFLSYRFNSLSQRLYCELTEREHEVSVELDVHPDLTVEAAELYKPDLIIAPFLKRKIPQEVWKKYKTLIIHPGPPGDRGPNALDWAIMKGERIWGVTLLEASEEYDAGDVWAYRTFPMRFARKASIYRNEVTEGVVECVLEALENFERGDFKPTPQKEHWWNPKMEQELRRVDWEQDDTKTVLRKVYASDSQPGASSKVLGKEVLLFNAYPEEELKGKPGEVLALRDEAVCIGTRDGAVWITHMRERKKESIKLPSARVLGEFLKGVKEDPIKPWEKVDFKTYREILYEEEDGIGFIHFNFYNGAMSTEQCYRLLETIKYAKKRPVKAIVLLGSEDFFSNGMNLNTIENAESPADESWRNINAIDDVCEEILKTPDKLTVAGMQGNAGFGGVFLALTCDLVFAREGVVLNPHYKNFGNLYGSEFWTYTLPKRVGWEKGKEVMENRMPISSKKAFEIGLIDGVFGKTPKEFRQRLKERIKNFINSKDFYEFIEKKKKERTSGEWLEEIQKCREHELEKMKLNFYGFDTSYHIARYYFVRRKPHFRTPPYLAIHRRLKFS 6jdq A 2.95 BS01 NUC B 1 S57 L58 A59 R62 R63 R66 R69 R70 L71 R73 R74 R75 H77 R78 R81 R83 R84 R88 L102 N108 P110 W111 H133 K136 H137 R138 G139 G190 H191 I192 R193 N194 Q195 R196 Y199 R205 T241 Q242 R243 L246 M254 P466 R473 P475 R479 R485 K486 R493 P834 R836 K837 M838 G840 Q841 G842 H843 V847 K848 S849 K851 L860 R861 N877 R880 E881 K909 Y910 D911 K912 T917 Q918 Q919 K921 A922 V923 R924 V933 R936 N937 N939 G940 R949 S966 W967 A970 K971 R1071 R1074 K1076 P1079 P1080 R1082 S50 L51 A52 R55 R56 R59 R62 R63 L64 R66 R67 R68 H70 R71 R74 R76 R77 R81 L95 N101 P103 W104 H126 K129 H130 R131 G132 G181 H182 I183 R184 N185 Q186 R187 Y190 R196 T232 Q233 R234 L237 M245 P452 R459 P461 R465 R471 K472 R479 P820 R822 K823 M824 G826 Q827 G828 H829 V833 K834 S835 K837 L846 R847 N863 R866 E867 K895 Y896 D897 K898 T903 Q904 Q905 K907 A908 V909 R910 V919 R922 N923 N925 G926 R935 S952 W953 A956 K957 R1057 R1060 K1062 P1065 P1066 R1068 3.1.-.- C9X1G5 SINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQNEGETADKELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDHALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAFDGKTIDKETGEVLHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVRS 6jdv A 3.10 BS01 NUC B 1 R48 S57 L58 A59 R62 R63 A65 R66 R69 R70 L71 T72 R73 R74 H77 R78 L79 R81 R84 R88 L102 N108 P110 W111 H133 K136 H137 R138 G139 Y140 Q143 G190 H191 I192 R193 N194 Q195 R196 R205 T241 Q242 R243 P244 A245 K253 T259 K269 F277 I278 V421 Q422 Y441 H452 Y453 K456 R473 N474 P475 L478 R479 S482 R485 K486 R493 R507 G510 Q523 N526 R527 R530 R557 D598 S599 F600 N668 R675 Q679 Q738 Q739 T742 R746 Y747 R836 K837 M838 S839 G840 Q841 G842 H843 V847 S849 K851 L860 R861 V876 N877 R880 E881 K909 D911 K912 T917 Q918 Q919 V920 K921 A922 V923 R924 V933 R936 N937 N939 G940 R949 S966 W967 A970 K971 Q1062 C1073 K1076 P1080 V1081 R1082 R41 S45 L46 A47 R50 R51 A53 R54 R57 R58 L59 T60 R61 R62 H65 R66 L67 R69 R72 R76 L90 N96 P98 W99 H121 K124 H125 R126 G127 Y128 Q131 G152 H153 I154 R155 N156 Q157 R158 R167 T203 Q204 R205 P206 A207 K215 T221 K231 F239 I240 V383 Q384 Y403 H414 Y415 K418 R435 N436 P437 L440 R441 S444 R447 K448 R455 R469 G472 Q485 N488 R489 R492 R519 D560 S561 F562 N624 R631 Q635 Q694 Q695 T698 R702 Y703 R790 K791 M792 S793 G794 Q795 G796 H797 V801 S803 K805 L814 R815 V830 N831 R834 E835 K863 D865 K866 T871 Q872 Q873 V874 K875 A876 V877 R878 V887 R890 N891 N893 G894 R903 S920 W921 A924 K925 Q1016 C1027 K1030 P1034 V1035 R1036 3.1.-.- C9X1G5 SINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYGKKNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDRNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAFDGKTIDTGEVLHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6jdv A 3.10 BS02 NUC C 1 Y140 R144 A245 L246 M254 L255 G256 K266 N285 R287 K333 K390 F417 D418 K419 F420 R440 D442 H452 Y453 R473 T505 A506 R507 E508 R516 K517 E520 Q523 K549 K555 K581 E585 I586 D587 A588 P591 S593 N611 Q612 G615 N616 R671 Y672 R675 G691 K692 K693 A736 Q739 M844 E845 T846 K870 Q981 N1029 E1048 G1049 I1050 G1051 V1052 K1053 T1054 Y128 R132 A207 L208 M216 L217 G218 K228 N247 R249 K295 K352 F379 D380 K381 F382 R402 D404 H414 Y415 R435 T467 A468 R469 E470 R478 K479 E482 Q485 K511 K517 K543 E547 I548 D549 A550 P553 S555 N573 Q574 G577 N578 R627 Y628 R631 G647 K648 K649 A692 Q695 M798 E799 T800 K824 Q935 N983 E1002 G1003 I1004 G1005 V1006 K1007 T1008 3.1.-.- C9X1G5 SINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYGKKNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDRNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAFDGKTIDTGEVLHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6jdv A 3.10 BS03 NUC D 1 A49 V928 N944 A945 T946 M947 Y965 K1013 H1024 R1025 G1026 T1027 R1033 A42 V882 N898 A899 T900 M901 Y919 K967 H978 R979 G980 T981 R987 3.1.-.- C9X1G5 SINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYGKKNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDRNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAFDGKTIDTGEVLHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6jdv A 3.10 BS04 MG A 1 D587 A588 N611 K614 G615 D549 A550 N573 K576 G577 3.1.-.- C9X1G5 SINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYGKKNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDRNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAFDGKTIDTGEVLHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6je3 A 2.93 BS01 NUC B 1 S57 L58 A59 R62 R63 A65 R66 R69 R70 L71 T72 R73 R74 H77 R78 L79 R81 R83 R84 R88 L102 N108 P110 W111 H133 K136 H137 R138 G139 Q143 H191 I192 R193 N194 Q195 R196 G197 D198 T202 R205 T241 Q242 R243 A245 T259 K269 F277 I278 V421 Q422 Y441 Y463 P466 R473 L478 R479 S482 R485 K486 K511 R836 K837 M838 S839 G840 A841 H842 L846 R847 S848 K850 K862 R863 W865 V878 N879 R884 E885 K916 K917 G918 Q920 L921 V922 K923 A924 V925 R926 V935 L937 N938 K939 N941 A942 T944 R953 A975 W976 A979 E980 C1073 R1074 L1075 P1080 R1082 S51 L52 A53 R56 R57 A59 R60 R63 R64 L65 T66 R67 R68 H71 R72 L73 R75 R77 R78 R82 L96 N102 P104 W105 H127 K130 H131 R132 G133 Q137 H178 I179 R180 N181 Q182 R183 G184 D185 T189 R192 T228 Q229 R230 A232 T246 K256 F264 I265 V404 Q405 Y424 Y442 P445 R452 L457 R458 S461 R464 K465 K489 R612 K613 M614 S615 G616 A617 H618 L622 R623 S624 K626 K638 R639 W641 V654 N655 R660 E661 K692 K693 G694 Q696 L697 V698 K699 A700 V701 R702 V711 L713 N714 K715 N717 A718 T720 R729 A751 W752 A755 E756 C849 R850 L851 P856 R858 3.1.-.- NPINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRARRLLKREGVLQAADFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKKELGALLKGVANNAHALQTGDFRTPAELALNKFEKESGHIRNQRGDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSSELQDEIGTAFSLFKTDEDITGRLKDRVQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPAIHIETAREVGKSFKDRKEIEFLCQFVADHILLTGKGKRRVFASNGQITNLLRGENDRHHALDAVVVACTVAMPWEFFAQEVMIRVFGKPDGKPEFEEADTPEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGAHKDTLRSAKRFVKHNEKISVKRVWLTEIKLADLENMVNYKNGREIELYEALKARLEAYGGNAKQAFDPKDNPFYKKGGQLVKAVRVEKTQESGVLLNKKNAYTIADNGDMVRVDVFCKVDKKGKNQYFIVPIYAWQVAENILPDIDCKGYRIDDSYTFCFSLHKYDLIAFQKDEKSKVEFAYYINCDSSNGRFYLAWHDKGSKEQQFRISTQNLVLIQKYQVNELGKEIRPCRLKKRPPVR 6je3 A 2.93 BS02 NUC C 1 Y140 R144 K145 G156 L158 L159 Y199 A245 L246 M254 L255 G256 K266 N285 R287 K333 G334 K390 D418 F420 R440 D442 E471 I472 K692 K843 D844 T845 K870 N1031 R1033 T1052 N1054 L1055 Y134 R138 K139 G143 L145 L146 Y186 A232 L233 M241 L242 G243 K253 N272 R274 K316 G317 K373 D401 F403 R423 D425 E450 I451 K515 K619 D620 T621 K646 N807 R809 T828 N830 L831 3.1.-.- NPINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRARRLLKREGVLQAADFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKKELGALLKGVANNAHALQTGDFRTPAELALNKFEKESGHIRNQRGDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSSELQDEIGTAFSLFKTDEDITGRLKDRVQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPAIHIETAREVGKSFKDRKEIEFLCQFVADHILLTGKGKRRVFASNGQITNLLRGENDRHHALDAVVVACTVAMPWEFFAQEVMIRVFGKPDGKPEFEEADTPEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGAHKDTLRSAKRFVKHNEKISVKRVWLTEIKLADLENMVNYKNGREIELYEALKARLEAYGGNAKQAFDPKDNPFYKKGGQLVKAVRVEKTQESGVLLNKKNAYTIADNGDMVRVDVFCKVDKKGKNQYFIVPIYAWQVAENILPDIDCKGYRIDDSYTFCFSLHKYDLIAFQKDEKSKVEFAYYINCDSSNGRFYLAWHDKGSKEQQFRISTQNLVLIQKYQVNELGKEIRPCRLKKRPPVR 6je3 A 2.93 BS03 NUC D 1 P52 K53 K843 T930 E932 N948 D950 M951 Y974 K1005 N1026 D1028 S1029 S1030 K1044 P46 K47 K619 T706 E708 N724 D726 M727 Y750 K781 N802 D804 S805 S806 K820 3.1.-.- NPINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRARRLLKREGVLQAADFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKKELGALLKGVANNAHALQTGDFRTPAELALNKFEKESGHIRNQRGDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSSELQDEIGTAFSLFKTDEDITGRLKDRVQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPAIHIETAREVGKSFKDRKEIEFLCQFVADHILLTGKGKRRVFASNGQITNLLRGENDRHHALDAVVVACTVAMPWEFFAQEVMIRVFGKPDGKPEFEEADTPEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGAHKDTLRSAKRFVKHNEKISVKRVWLTEIKLADLENMVNYKNGREIELYEALKARLEAYGGNAKQAFDPKDNPFYKKGGQLVKAVRVEKTQESGVLLNKKNAYTIADNGDMVRVDVFCKVDKKGKNQYFIVPIYAWQVAENILPDIDCKGYRIDDSYTFCFSLHKYDLIAFQKDEKSKVEFAYYINCDSSNGRFYLAWHDKGSKEQQFRISTQNLVLIQKYQVNELGKEIRPCRLKKRPPVR 6je4 A 3.07 BS01 NUC C 1 Y140 R144 K145 G156 L158 L159 Y199 A245 L246 M254 L255 K266 N285 R287 E294 K333 G334 K390 S416 F417 D418 K419 F420 R440 D442 R473 K656 F657 D658 Y672 R675 M844 E845 T846 Q981 K1013 T1027 N1029 E1048 G1049 I1050 G1051 K1053 T1054 Y133 R137 K138 G142 L144 L145 Y185 A231 L232 M240 L241 K252 N271 R273 E280 K319 G320 K376 S402 F403 D404 K405 F406 R426 D428 R454 K637 F638 D639 Y653 R656 M811 E812 T813 Q948 K980 T994 N996 E1015 G1016 I1017 G1018 K1020 T1021 3.1.-.- C9X1G5 SINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6je4 A 3.07 BS02 NUC D 1 P52 K53 V928 K930 N944 A945 T946 M947 Y965 H1024 R1025 T1027 R1033 P45 K46 V895 K897 N911 A912 T913 M914 Y932 H991 R992 T994 R1000 3.1.-.- C9X1G5 SINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6je4 A 3.07 BS03 NUC B 1 R44 S57 L58 A59 R62 R63 R66 R69 R70 L71 T72 R73 R74 R75 H77 R78 L79 R81 R83 R84 R88 L102 N108 P110 W111 H133 K136 H137 R138 G139 Q143 G190 H191 I192 R193 N194 Q195 R196 R205 T241 Q242 R243 P244 A245 T259 F277 I278 V421 Q422 Y441 P466 R473 P475 L478 R479 R485 K486 R493 L654 R665 T670 R675 P834 N835 R836 K837 M838 S839 G840 Q841 G842 H843 V847 K848 S849 K851 R861 V876 N877 R880 E881 K883 D911 K912 T917 Q918 Q919 K921 A922 V923 R924 V933 R936 N939 G940 R949 S966 W967 A970 K971 Q1062 E1065 R1071 C1073 K1076 P1079 P1080 V1081 R1082 R37 S50 L51 A52 R55 R56 R59 R62 R63 L64 T65 R66 R67 R68 H70 R71 L72 R74 R76 R77 R81 L95 N101 P103 W104 H126 K129 H130 R131 G132 Q136 G176 H177 I178 R179 N180 Q181 R182 R191 T227 Q228 R229 P230 A231 T245 F263 I264 V407 Q408 Y427 P447 R454 P456 L459 R460 R466 K467 R474 L635 R646 T651 R656 P801 N802 R803 K804 M805 S806 G807 Q808 G809 H810 V814 K815 S816 K818 R828 V843 N844 R847 E848 K850 D878 K879 T884 Q885 Q886 K888 A889 V890 R891 V900 R903 N906 G907 R916 S933 W934 A937 K938 Q1029 E1032 R1038 C1040 K1043 P1046 P1047 V1048 R1049 3.1.-.- C9X1G5 SINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6je4 E 3.07 BS02 NUC H 1 R48 P52 K53 V928 K930 N944 A945 T946 M947 Y965 H1024 R1025 G1026 T1027 R1033 R47 P51 K52 V902 K904 N918 A919 T920 M921 Y939 H998 R999 G1000 T1001 R1007 3.1.-.- C9X1G5 AAFKPNSINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNALHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6je4 E 3.07 BS03 NUC F 1 R44 S57 L58 A59 R62 R63 R66 R69 R70 L71 T72 R73 R74 R75 H77 R78 L79 R81 R83 R84 R88 L102 N108 P110 W111 H133 K136 H137 R138 G139 Y140 Q143 G190 H191 I192 R193 N194 Q195 R196 R205 T241 Q242 R243 A245 T259 K269 F277 I278 V421 Q422 Y441 P466 R473 P475 L478 R479 S482 R485 K486 R493 Q650 R665 T670 R675 P834 N835 R836 K837 M838 S839 G840 Q841 G842 H843 V847 S849 K851 L860 R861 V876 N877 R880 E881 K909 K912 T917 Q918 Q919 K921 A922 V923 R924 V933 R936 N939 G940 R949 S966 W967 A970 K971 Q1062 R1071 C1073 R1074 L1075 K1076 P1079 P1080 V1081 R1082 R43 S56 L57 A58 R61 R62 R65 R68 R69 L70 T71 R72 R73 R74 H76 R77 L78 R80 R82 R83 R87 L101 N107 P109 W110 H132 K135 H136 R137 G138 Y139 Q142 G182 H183 I184 R185 N186 Q187 R188 R197 T233 Q234 R235 A237 T251 K261 F269 I270 V413 Q414 Y433 P453 R460 P462 L465 R466 S469 R472 K473 R480 Q637 R652 T657 R662 P808 N809 R810 K811 M812 S813 G814 Q815 G816 H817 V821 S823 K825 L834 R835 V850 N851 R854 E855 K883 K886 T891 Q892 Q893 K895 A896 V897 R898 V907 R910 N913 G914 R923 S940 W941 A944 K945 Q1036 R1045 C1047 R1048 L1049 K1050 P1053 P1054 V1055 R1056 3.1.-.- C9X1G5 AAFKPNSINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNALHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6je4 K 3.07 BS01 NUC M 1 Y140 R144 G156 L158 L159 Y199 A245 L246 M254 L255 G256 K266 N285 R287 K333 G334 K390 D418 K419 F420 R440 D442 R473 K656 F657 D658 Y672 R675 M844 E845 T846 K958 Q981 T1027 N1029 K1043 E1048 G1049 I1050 G1051 V1052 K1053 T1054 Y139 R143 G153 L155 L156 Y196 A242 L243 M251 L252 G253 K263 N282 R284 K330 G331 K387 D415 K416 F417 R437 D439 R465 K648 F649 D650 Y664 R667 M822 E823 T824 K936 Q959 T1005 N1007 K1021 E1026 G1027 I1028 G1029 V1030 K1031 T1032 3.1.-.- C9X1G5 AAFKPNSINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNETADKELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6je4 O 3.07 BS01 NUC Q 1 Y140 Q143 R144 K145 G156 L158 L159 Y199 A245 L246 M254 L255 K266 N285 R287 K333 G334 K390 S416 D418 K419 F420 R440 D442 R473 K656 F657 D658 Y672 R675 M844 E845 T846 Q981 T1027 N1029 E1048 G1049 I1050 G1051 V1052 K1053 T1054 Y136 Q139 R140 K141 G145 L147 L148 Y188 A234 L235 M243 L244 K255 N274 R276 K322 G323 K379 S405 D407 K408 F409 R429 D431 R457 K640 F641 D642 Y656 R659 M811 E812 T813 Q948 T994 N996 E1015 G1016 I1017 G1018 V1019 K1020 T1021 3.1.-.- C9X1G5 KPNSINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNATHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6je4 O 3.07 BS02 NUC R 1 R48 P52 K53 V928 K930 N944 A945 T946 M947 Y965 K1013 H1024 R1025 T1027 R1033 R44 P48 K49 V895 K897 N911 A912 T913 M914 Y932 K980 H991 R992 T994 R1000 3.1.-.- C9X1G5 KPNSINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNATHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6je4 O 3.07 BS03 NUC P 1 R44 S57 L58 A59 R62 R63 R66 R69 R70 L71 T72 R73 R74 H77 R78 L79 R81 R83 R84 R88 L102 N108 P110 W111 H133 H137 R138 G139 Y140 Q143 G190 H191 I192 R193 N194 Q195 R196 R205 T241 Q242 R243 A245 T259 K269 F277 I278 V421 Q422 Y441 P466 R473 P475 L478 R479 R485 K486 R493 L654 R665 T670 R675 P834 N835 R836 K837 M838 S839 G840 Q841 G842 H843 V847 S849 K851 R861 V876 N877 R880 E881 K883 K912 T917 Q919 V920 K921 A922 V923 R924 V933 R936 N939 G940 R949 S966 W967 A970 K971 Q1062 E1065 R1071 C1073 K1076 P1079 P1080 V1081 R1082 R40 S53 L54 A55 R58 R59 R62 R65 R66 L67 T68 R69 R70 H73 R74 L75 R77 R79 R80 R84 L98 N104 P106 W107 H129 H133 R134 G135 Y136 Q139 G179 H180 I181 R182 N183 Q184 R185 R194 T230 Q231 R232 A234 T248 K258 F266 I267 V410 Q411 Y430 P450 R457 P459 L462 R463 R469 K470 R477 L638 R649 T654 R659 P801 N802 R803 K804 M805 S806 G807 Q808 G809 H810 V814 S816 K818 R828 V843 N844 R847 E848 K850 K879 T884 Q886 V887 K888 A889 V890 R891 V900 R903 N906 G907 R916 S933 W934 A937 K938 Q1029 E1032 R1038 C1040 K1043 P1046 P1047 V1048 R1049 3.1.-.- C9X1G5 KPNSINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNATHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6je9 A 3.46 BS01 NUC B 1 S57 L58 R62 R63 A65 R66 V68 R69 R70 L71 R73 R74 H77 R78 R81 R84 R88 L102 N108 P110 W111 H133 K136 H137 R138 G139 Y140 Q143 L158 G190 H191 I192 R193 N194 Q195 R196 Y199 R205 T241 Q242 R243 L246 M254 Y463 P466 R473 P475 R479 R485 K486 R493 P834 N835 R836 K837 M838 S839 G840 Q841 G842 H843 V847 S849 K851 L860 R861 V876 N877 R880 K909 K912 T917 Q918 Q919 K921 A922 V923 R924 R936 N937 N939 R949 S966 W967 A970 K971 Q1062 R1071 R1074 K1076 P1080 V1081 R1082 S50 L51 R55 R56 A58 R59 V61 R62 R63 L64 R66 R67 H70 R71 R74 R77 R81 L95 N101 P103 W104 H126 K129 H130 R131 G132 Y133 Q136 L148 G180 H181 I182 R183 N184 Q185 R186 Y189 R195 T231 Q232 R233 L236 M244 Y447 P450 R457 P459 R463 R469 K470 R477 P807 N808 R809 K810 M811 S812 G813 Q814 G815 H816 V820 S822 K824 L833 R834 V849 N850 R853 K882 K885 T890 Q891 Q892 K894 A895 V896 R897 R909 N910 N912 R922 S939 W940 A943 K944 Q1035 R1044 R1047 K1049 P1053 V1054 R1055 3.1.-.- C9X1G5 SINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQEGETADKELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDHALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAFVLHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVRS 6je9 C 3.46 BS01 NUC D 1 S57 L58 A59 R62 R63 A65 R66 V68 R69 R70 L71 T72 R73 R74 H77 R78 L79 R81 R83 R84 R88 L106 N108 P110 W111 H133 K136 H137 R138 G139 Y140 G190 H191 I192 R193 N194 Q195 R196 Y199 R205 T241 Q242 R243 A245 L246 M254 P466 R473 R479 R485 K486 R493 P834 N835 R836 K837 M838 S839 G840 Q841 G842 H843 V847 S849 K851 L860 R861 N877 R880 E881 T917 Q918 Q919 V920 K921 A922 V923 R924 R936 N937 N939 R949 S966 W967 A970 K971 E1065 P1080 V1081 R1082 S50 L51 A52 R55 R56 A58 R59 V61 R62 R63 L64 T65 R66 R67 H70 R71 L72 R74 R76 R77 R81 L99 N101 P103 W104 H126 K129 H130 R131 G132 Y133 G178 H179 I180 R181 N182 Q183 R184 Y187 R193 T229 Q230 R231 A233 L234 M242 P445 R452 R458 R464 K465 R472 P791 N792 R793 K794 M795 S796 G797 Q798 G799 H800 V804 S806 K808 L817 R818 N834 R837 E838 T870 Q871 Q872 V873 K874 A875 V876 R877 R889 N890 N892 R902 S919 W920 A923 K924 E1018 P1033 V1034 R1035 3.1.-.- C9X1G5 SINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQETADKELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEITEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDHALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVRS 6jfu A 3.20 BS01 NUC B 1 R44 S57 L58 A59 R62 R63 A65 R66 R69 R70 L71 T72 R74 R75 H77 R78 L79 R81 R83 L102 N108 P110 W111 H133 K136 H137 R138 G139 H191 I192 R193 N194 Q195 R196 G197 D198 R205 Q242 R243 P244 A245 T259 K269 F277 I278 V421 Q422 Y441 Y463 P466 R473 R479 K511 R675 R746 P834 R836 K837 M838 S839 G840 A841 H842 L846 R847 S848 K850 R863 W865 V878 N879 R884 E885 K916 K917 Q920 L921 K923 A924 V925 R926 L937 N938 N941 A942 T944 R953 A975 W976 A979 E980 C1073 R1074 L1075 P1080 R38 S51 L52 A53 R56 R57 A59 R60 R63 R64 L65 T66 R68 R69 H71 R72 L73 R75 R77 L96 N102 P104 W105 H127 K130 H131 R132 G133 H185 I186 R187 N188 Q189 R190 G191 D192 R199 Q236 R237 P238 A239 T253 K263 F271 I272 V409 Q410 Y429 Y451 P454 R461 R467 K499 R515 R572 P636 R638 K639 M640 S641 G642 A643 H644 L648 R649 S650 K652 R665 W667 V680 N681 R686 E687 K718 K719 Q722 L723 K725 A726 V727 R728 L739 N740 N743 A744 T746 R755 A777 W778 A781 E782 C875 R876 L877 P882 3.1.-.- NPINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRARRLLKREGVLQAADFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNEGETADKELGALLKGVANNAHALQTGDFRTPAELALNKFEKESGHIRNQRGDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLREASTLMEMKAYHAISRALEKEGLKDKKSPLNLSSELQDEIGTAFSLFKTDEDITGRLKDRVQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYGKKNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEDTRYVNRFLCQFVADHIVFASNGQITNLLRGKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTPEKLRTLLAEKLPEAVHEYVTPLFVSRAPNRKMSGAHKDTLRSAKRFVKHNEKISVKRVWLTEIKLADLENMVNYKNGREIELYEALKARLEAYGGNAKQAFDPKDNPFYKKGGQLVKAVRVEKTQESGVLLNKKNAYTIADNGDMVRVDVFCKVDKKGKNQYFIVPIYAWQVAENILPDIDCKGYRIDDSYTFCFSLHKYDLIAFQKDEKSKVEFAYYINCDSSNGRFYLAWHDKGSKEQQFRISTQNLVLIQKYQVNELGKEIRPCRLKKRPPVR 6jfu A 3.20 BS02 NUC C 1 Y140 R144 K145 G156 L158 L159 Y199 A245 L246 M254 L255 G256 K266 N285 R287 K333 K390 D418 F420 D442 I472 R473 T670 R671 Y672 V673 R675 K843 D844 T845 K862 K870 R1033 I1050 T1052 N1054 Y134 R138 K139 G150 L152 L153 Y193 A239 L240 M248 L249 G250 K260 N279 R281 K327 K378 D406 F408 D430 I460 R461 T510 R511 Y512 V513 R515 K645 D646 T647 K664 K672 R835 I852 T854 N856 3.1.-.- NPINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRARRLLKREGVLQAADFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNEGETADKELGALLKGVANNAHALQTGDFRTPAELALNKFEKESGHIRNQRGDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLREASTLMEMKAYHAISRALEKEGLKDKKSPLNLSSELQDEIGTAFSLFKTDEDITGRLKDRVQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYGKKNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEDTRYVNRFLCQFVADHIVFASNGQITNLLRGKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTPEKLRTLLAEKLPEAVHEYVTPLFVSRAPNRKMSGAHKDTLRSAKRFVKHNEKISVKRVWLTEIKLADLENMVNYKNGREIELYEALKARLEAYGGNAKQAFDPKDNPFYKKGGQLVKAVRVEKTQESGVLLNKKNAYTIADNGDMVRVDVFCKVDKKGKNQYFIVPIYAWQVAENILPDIDCKGYRIDDSYTFCFSLHKYDLIAFQKDEKSKVEFAYYINCDSSNGRFYLAWHDKGSKEQQFRISTQNLVLIQKYQVNELGKEIRPCRLKKRPPVR 6jfu A 3.20 BS03 NUC D 1 T930 E932 N948 D950 M951 Y974 N1026 D1028 S1029 S1030 K1044 T732 E734 N750 D752 M753 Y776 N828 D830 S831 S832 K846 3.1.-.- NPINYILGLAIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRARRLLKREGVLQAADFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNEGETADKELGALLKGVANNAHALQTGDFRTPAELALNKFEKESGHIRNQRGDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLREASTLMEMKAYHAISRALEKEGLKDKKSPLNLSSELQDEIGTAFSLFKTDEDITGRLKDRVQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYGKKNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEDTRYVNRFLCQFVADHIVFASNGQITNLLRGKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTPEKLRTLLAEKLPEAVHEYVTPLFVSRAPNRKMSGAHKDTLRSAKRFVKHNEKISVKRVWLTEIKLADLENMVNYKNGREIELYEALKARLEAYGGNAKQAFDPKDNPFYKKGGQLVKAVRVEKTQESGVLLNKKNAYTIADNGDMVRVDVFCKVDKKGKNQYFIVPIYAWQVAENILPDIDCKGYRIDDSYTFCFSLHKYDLIAFQKDEKSKVEFAYYINCDSSNGRFYLAWHDKGSKEQQFRISTQNLVLIQKYQVNELGKEIRPCRLKKRPPVR 6jt5 A 1.50 BS01 CA A 1 S449 L450 D451 S209 L210 D211 A0A0A8IDB7 31604769 FVSCPGAPQPRYQMNVANGFRVAPVLGGLTMPRGITLDTRGNLLVVERGRGLTGHTLDANGCVTSSKVVIQDTQINHGIDVHPSGRRIIASSGDIAWSWDYDPATMTATNRRTLVTGMNNFYHFTRTVHISRKYPNLFALNVGSDGNIDVPTRQQNSGRAQIRVFDYDQLPQNGVPFVSQYGRVLGYGLRNDVGITEDRAGNIHSIENSLDNAYRMVNGQRRDIHTNNPAEKVYNLGDPSNPRAIFGGYPDCYTVWEPSDFTDSPKQPGDWFTQDNSGQYTDAWCNANAVKPTLLLPPHTAPLDMKFGLGNDTNLYVALHGSWNRQPPQGYKVVVVPGQYSASGEWSPTAPLAQSRTAWSDLLTNRNENQCSGFGNANCFRPVGLVWSADGQNLYVSSDTSGEVFIIKR 6ju1 A 1.60 BS01 FAD A 1 I8 G9 G11 P12 S13 E32 R33 Q34 V39 R42 R44 A45 G46 V47 Q102 V127 C158 D159 G160 G163 I164 G285 D286 A296 K297 G298 L299 N300 I9 G10 G12 P13 S14 E33 R34 Q35 V40 R43 R45 A46 G47 V48 Q103 V128 C159 D160 G161 G164 I165 G286 D287 A297 K298 G299 L300 N301 1.14.13.2 A0A367MFY2 31639299 HMKTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGRIRAGVLEQGMVDLLREAGVDRRMARDGLVHEGVEIAFAGQRRRIDLKRLSGGKTVTVYGQTEVTRDLMEAREACGATTVYQAAEVRLHDLQGERPYVTFERDGERLRLDCDYIAGCDGFHGISRQSIPAERLKVFERVYPFGWLGLLADTPPVSHELIYANHPRGFALCSQRSATRSRYYVQVPLSEKVEDWSDERFWTELKARLPSEVAEKLVTGPSLEKSIAPLRSFVVEPMQHGRLFLAGDAAHIVPPTGAKGLNLAASDVSTLYRLLLKAYREGRGELLERYSAICLRRIWKAERFSWWMTSVLHRFPDTDAFSQRIQQTELEYYLGSEAGLATIAENFVGLPYEE 6juh A 3.00 BS01 C9X D 1 M1174 T1175 L1176 T1206 M174 T175 L176 T206 A8EVM5 30981510 MYLRITNIVESSFFTKFIIYLIVLNGITMGLETSKTFMQSFGVYTTLFNQIVITIFTIEIILRIYVHRISFFKDPWSLFDFFVVAISLVPTSSGFEILRVLRVLRLFRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLFGERFPEWFGTLGESFYTLFQVMTLDDWSNGIVRPLMEVYPYAWVFFIPFIFVVTFVMINLVVAIIVDAMAILNQKEEQHIIDEVQSHEDNINNEIIKLREEIVELKELIKT 6juh B 3.00 BS01 C9X D 1 L1176 T1206 I1210 L176 T206 I210 A8EVM5 30981510 MYLRITNIVESSFFTKFIIYLIVLNGITMGLETSKTFMQSFGVYTTLFNQIVITIFTIEIILRIYVHRISFFKDPWSLFDFFVVAISLVPTSSGFEILRVLRVLRLFRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLFGERFPEWFGTLGESFYTLFQVMTLDDWSNGIVRPLMEVYPYAWVFFIPFIFVVTFVMINLVVAIIVDAMAILNQKEEQHIIDEVQSHEDNINNEIIKLREEIVELKELIKT 6juh C 3.00 BS01 G3P C 1 T1162 L1163 G1164 T162 L163 G164 A8EVM5 30981510 MYLRITNIVESSFFTKFIIYLIVLNGITMGLETSKTFMQSFGVYTTLFNQIVITIFTIEIILRIYVHRISFFKDPWSLFDFFVVAISLVPTSSGFEILRVLRVLRLFRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLFGERFPEWFGTLGESFYTLFQVMTLDDWSNGIVRPLMEVYPYAWVFFIPFIFVVTFVMINLVVAIIVDAMAILNQKEEQHIIDEVQSHEDNINNEIIKLREEIVELKELI 6juh D 3.00 BS01 C9X D 1 T1175 L1176 I1210 T175 L176 I210 A8EVM5 30981510 MYLRITNIVESSFFTKFIIYLIVLNGITMGLETSKTFMQSFGVYTTLFNQIVITIFTIEIILRIYVHRISFFKDPWSLFDFFVVAISLVPTSSGFEILRVLRVLRLFRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLFGERFPEWFGTLGESFYTLFQVMTLDDWSNGIVRPLMEVYPYAWVFFIPFIFVVTFVMINLVVAIIVDAMAILNQKEEQHIIDEVQSHEDNINNEIIKLREEIVELKELIKT 6jwf A 1.30 BS01 CA A 1 S449 D451 S209 D211 A0A0A8IDB7 FVSCPGAPQPRYQMNVANGFRVAPVLGGLTMPRGITLDTRGNLLVVERGRGLTGHTLDANGCVTSSKVVIQDTQINHGIDVHPSGRRIIASSGDIAWSWDYDPATMTATNRRTLVTGMNNFYHFTRTVHISRKYPNLFALNVGSDGNIDVPTRQQNSGRAQIRVFDYDQLPQNGVPFVSQYGRVLGYGLRNDVGITEDRAGNIHSIENSLDNAYRMVNGQRRDIHTNNPAEKVYNLGDPSNPRAIFGGYPDCYTVWEPSDFTDSPKQPGDWFTQDNSGQYTDAWCNANAVKPTLLLPPHTAPLDMKFGLGNDTNLYVALHGSWNRQPPQGYKVVVVPGQYSASGEWSPTAPLAQSRTAWSDLLTNRNENQCSGFGNANCFRPVGLVWSADGQNLYVSSDTSGEVFIIKR 6jwf A 1.30 BS02 PQQ A 1 R273 H363 R430 N431 N448 S449 D451 H539 A541 L543 H560 G561 S562 W563 N564 R621 R33 H123 R190 N191 N208 S209 D211 H299 A301 L303 H320 G321 S322 W323 N324 R381 A0A0A8IDB7 FVSCPGAPQPRYQMNVANGFRVAPVLGGLTMPRGITLDTRGNLLVVERGRGLTGHTLDANGCVTSSKVVIQDTQINHGIDVHPSGRRIIASSGDIAWSWDYDPATMTATNRRTLVTGMNNFYHFTRTVHISRKYPNLFALNVGSDGNIDVPTRQQNSGRAQIRVFDYDQLPQNGVPFVSQYGRVLGYGLRNDVGITEDRAGNIHSIENSLDNAYRMVNGQRRDIHTNNPAEKVYNLGDPSNPRAIFGGYPDCYTVWEPSDFTDSPKQPGDWFTQDNSGQYTDAWCNANAVKPTLLLPPHTAPLDMKFGLGNDTNLYVALHGSWNRQPPQGYKVVVVPGQYSASGEWSPTAPLAQSRTAWSDLLTNRNENQCSGFGNANCFRPVGLVWSADGQNLYVSSDTSGEVFIIKR 6k31 A 2.60 BS01 CO A 1 K332 H352 K490 D656 K312 H332 K466 D612 4.1.1.38 PTNSANSAIALRLELLGAPVPETDRLVAPILARQRELTRRLANRPCAADRRIQAFLDSYLDGAAAQPKLPGATLVLDQPGLARALSLPVDATSFTSDYVESYRVLSGVLHNPRNDRRTTAGVFHVAEGGLPIPDDKKAVPRDVFARVLAAAVDAPDDLTLPWASTQADPARCFVSLLLRPVVVPEVPGFSAERSEIRFIAPGGLVSNLDFVEGIFGNGGDPYLPENDASLAPESWTGHTGCVILAPHLTRLTKKELGLPAWEEATERQRRDGCWRGADELYNDGKAFKLVARDERGVIVTIIADNYYGYCKKEVKTQISYSANLFGCVEEEHSGGALAFPRYNLGQEYTDVHTPAGATVERVLARNPGRFEARADGSAVLLDDDGRPDEGIVLVPAGAHFSRTQTVTWDRREASIPLLADRVYIAPGGYRVHAKHREGDATQWHLVGTAPWATQAHKPATVSGGGKSEISKSLLDAFVFGEAYVGDVDADLDAVQKILDPILSERRSLGSVIKLLTPSSYTEEYNAFLESIPAHIKELIFTVKRYYQPGWGADWRSHFSVGIINGRKGNSLRLDGEVIKVNLRVGFEDDGAWRLLSLRPDFSPAAKVQTEDDITSSIVAPGGLESTAGSSVSRKFVTNCESLLFQRPDDAIVRGYDKQTERDSGTGLFISNYQPLTPADARAVADAPGLSRFTEPQELVRRAAAIPEAPREETYWTSTANPRLVGGAPTRNPRYLQVRPDIANPRDVALADLSIHLYRDAPLAAPARHGVDVVAAGRRNNPPEPGVPALCAYNPLHYELPELFEFISSTGKSPSTTGAGSEGALTKSPFNALPPVYDLNAALLSYALGGYDGWLSSAGYIGPKVKVAHDISLLVPEIFSRTPQERDARALIEAGYLERLEDFDHEGRRIEASRLGYRNAAFATAYFGRIFLHPDVVFTEELRPELQDPAIFADSVEVIVATHRAVAKHYVDDGSIQWAVPPLKALLEIYSGRSEEGWTLSSPELRALFERENILASDWYAERVDAKVERDRKQAESAIAALTRFTTTQGNEEVTERLDIEGRLASARAWLDEVTSPAYRAHLVGTLGLQPSLA 6k3l B 2.09 BS01 3NG B 1 V44 G45 R46 G47 V52 I65 K67 T112 Y114 V115 M162 I173 D174 V40 G41 R42 G43 V48 I61 K63 T108 Y110 V111 M158 I169 D170 A0A226BA59 31591414 RSVARVYANVNEKLGRSWWDYDNLVVQWGVQDNYEIVRKVGRGKYSEVFESIHLPTDSKCIVKVLKPVKKKKIKREIKILQNLAGGPNVVGLLDVVRDSQSKTPSIVTEYVNNTEFKTLYPKFSDFDVRYYIFELLKALDFCHSKGIMHRDVKPHNVMIDHEKRTLRLIDWGLAEFYHPGTEYNVRVASRYFKGPELLVDFQEYDYSLDMWSLGCMFASMIFRKEPFFHGHDNADQLVKIAKVLGTDELYTYLERYDIDLDAQFDDILGRYPRKPWSRFVSSENQRYISSEAIDFLDKLLRYDHQERLTAEEAKEHPYFEPVRQAAAQA 6k7t A 1.60 BS01 III C 1 Y7 Y9 Y62 R65 N66 N69 A73 T76 Y77 V79 G80 N83 V84 Y87 R100 Y102 T146 K149 W150 Y155 R158 D159 Y162 W170 Y7 Y9 Y62 R65 N66 N69 A73 T76 Y77 V79 G80 N83 V84 Y87 R100 Y102 T146 K149 W150 Y155 R158 D159 Y162 W170 A0A125R585 31498797 GFHSLRYFYTAWSRPGSGEPRFVAVGYVDDTQFVRFDSDNASPRAEPRAPWMDLVEQQDPQYWDRNTRNARDAAQTYRVGLDNVRGYYNQSEAGSHTIQRMYGCDVGPHGRLLRGYDQLAYDGADYIALNEDLRSWTAADLAAQNTRRKWEEAGYAERDRAYLEGECVEWLLKHLENGRETLLRADPPKTHITHHPIVTLRCWALGFYPEEITLTWMELVETRPDGNGAFQKWAAYTCHVQHEGLPQPLTLRW 6kc7 A 3.30 BS01 NUC B 1 S57 A59 R62 R63 A65 R66 V68 R69 R70 L71 R73 R74 R75 H77 R78 L79 R84 R88 L102 L106 N108 P110 W111 H133 K136 R138 G139 Q143 G190 H191 I192 R193 N194 Q195 R196 S197 Y199 T202 R205 T241 Q242 R243 P466 P475 L478 R479 R485 K486 R493 P834 R836 K837 M838 S839 G840 Q841 G842 H843 V847 S849 K851 V859 L860 R861 N877 R880 K883 K909 D911 K912 T917 Q918 Q919 V920 K921 A922 V923 R924 R936 N939 G940 S966 W967 A970 K971 Q1062 E1065 R1071 P1080 V1081 R1082 S50 A52 R55 R56 A58 R59 V61 R62 R63 L64 R66 R67 R68 H70 R71 L72 R77 R81 L95 L99 N101 P103 W104 H126 K129 R131 G132 Q136 G173 H174 I175 R176 N177 Q178 R179 S180 Y182 T185 R188 T224 Q225 R226 P353 P362 L365 R366 R372 K373 R380 P715 R717 K718 M719 S720 G721 Q722 G723 H724 V728 S730 K732 V740 L741 R742 N758 R761 K764 K790 D792 K793 T798 Q799 Q800 V801 K802 A803 V804 R805 R817 N820 G821 S847 W848 A851 K852 Q943 E946 R952 P961 V962 R963 3.1.-.- C9X1G5 SINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKTYAQARKLLASTLMEMKAYHAISRSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIISFDKFVQIEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAFDGKTIDLHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6kc7 A 3.30 BS02 NUC C 1 G156 A157 L158 L159 Y199 L246 K390 M844 E845 T846 Q981 T1027 N1029 G1049 I1050 G1051 V1052 K1053 T1054 G139 A140 L141 L142 Y182 L229 K324 M725 E726 T727 Q862 T908 N910 G930 I931 G932 V933 K934 T935 3.1.-.- C9X1G5 SINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKTYAQARKLLASTLMEMKAYHAISRSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIISFDKFVQIEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAFDGKTIDLHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6kc7 A 3.30 BS03 NUC D 1 V928 K930 N944 A945 T946 M947 Y965 K1013 H1024 R1025 T1027 R1033 V809 K811 N825 A826 T827 M828 Y846 K894 H905 R906 T908 R914 3.1.-.- C9X1G5 SINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPKTGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQELGALLKGVAGNAHALQTGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKTYAQARKLLASTLMEMKAYHAISRSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIISFDKFVQIEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFPNFVGEPKSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDAALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQKFDEDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAFDGKTIDLHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6kc8 A 2.90 BS01 NUC B 1 R48 S57 A59 M60 R62 R63 R66 V68 R69 R70 L71 R73 R74 R75 H77 R78 R81 R84 R88 N108 P110 W111 H133 K136 H137 R138 G139 Y140 Q143 G190 H191 I192 R193 N194 Q195 R196 R205 Q242 R243 A245 K253 T259 K269 F277 V421 Q422 Y441 H452 Y453 K456 R473 N474 P475 R479 S482 K486 R493 R507 G510 Q523 N526 R527 R530 R665 N666 N668 D669 R675 Q679 Q738 Q739 T742 R746 Y747 P834 R836 K837 M838 S839 G840 Q841 G842 H843 V847 K848 S849 K851 L860 R861 V876 N877 R880 E881 K909 D911 T917 Q918 Q919 K921 A922 V923 R924 R936 N937 N939 G940 R949 S966 W967 A970 K971 Q1062 E1065 R1071 C1073 R1074 K1076 P1080 V1081 R1082 R41 S48 A50 M51 R53 R54 R57 V59 R60 R61 L62 R64 R65 R66 H68 R69 R72 R75 R79 N99 P101 W102 H124 K127 H128 R129 G130 Y131 Q134 G158 H159 I160 R161 N162 Q163 R164 R173 Q210 R211 A213 K221 T227 K237 F245 V389 Q390 Y409 H420 Y421 K424 R441 N442 P443 R447 S450 K454 R461 R475 G478 Q491 N494 R495 R498 R621 N622 N624 D625 R631 Q635 Q694 Q695 T698 R702 Y703 P788 R790 K791 M792 S793 G794 Q795 G796 H797 V801 K802 S803 K805 L814 R815 V830 N831 R834 E835 K863 D865 T871 Q872 Q873 K875 A876 V877 R878 R890 N891 N893 G894 R903 S920 W921 A924 K925 Q1016 E1019 R1025 C1027 R1028 K1030 P1034 V1035 R1036 3.1.-.- C9X1G5 SINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNETGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYGKKNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDHALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAFDGKTIDTGEVLHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6kc8 A 2.90 BS02 NUC C 1 Y140 Q143 R144 K145 A245 L246 M254 L255 G256 K266 N285 R287 K333 K390 D418 K419 F420 R440 D442 H452 Y453 R473 A506 R507 E508 K511 R516 K517 I519 E520 Q523 R671 Y672 R675 K690 G691 K692 K693 A736 Q739 Y131 Q134 R135 K136 A213 L214 M222 L223 G224 K234 N253 R255 K301 K358 D386 K387 F388 R408 D410 H420 Y421 R441 A474 R475 E476 K479 R484 K485 I487 E488 Q491 R627 Y628 R631 K646 G647 K648 K649 A692 Q695 3.1.-.- C9X1G5 SINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNETGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYGKKNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDHALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAFDGKTIDTGEVLHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6kc8 A 2.90 BS03 NUC D 1 V928 K930 N944 A945 T946 M947 Y965 Q981 K1013 H1024 R1025 G1026 R1033 V882 K884 N898 A899 T900 M901 Y919 Q935 K967 H978 R979 G980 R987 3.1.-.- C9X1G5 SINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNETGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYGKKNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDHALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAFDGKTIDTGEVLHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6kc8 A 2.90 BS04 NUC P 1 M844 E845 T846 K870 Q981 K1013 T1027 N1029 G1049 I1050 G1051 K1053 T1054 M798 E799 T800 K824 Q935 K967 T981 N983 G1003 I1004 G1005 K1007 T1008 3.1.-.- C9X1G5 SINYILGLDIGIASVGWAMVEIDEEENPIRLIDLGVRVFERAEVPGDSLAMARRLARSVRRLTRRRAHRLLRTRRLLKREGVLQAANFDENGLIKSLPNTPWQLRAAALDRKLTPLEWSAVLLHLIKHRGYLSQRKNETGDFRTPAELALNKFEKESGHIRNQRSDYSHTFSRKDLQAELILLFEKQKEFGNPHVSGGLKEGIETLLMTQRPALSGDAVQKMLGHCTFEPAEPKAAKNTYTAERFIWLTKLNNLRILEQGSERPLTDTERATLMDEPYRKSKLTYAQARKLLGLEDTAFFKGLRYGKDNAEASTLMEMKAYHAISRALEKEGLKDKKSPLNLSPELQDEIGTAFSLFKTDEDITGRLKDRIQPEILEALLKHISFDKFVQISLKALRRIVPLMEQGKRYDEACAEIYGDHYGKKNTEEKIYLPPIPADEIRNPVVLRALSQARKVINGVVRRYGSPARIHIETAREVGKSFKDRKEIEKRQEENRKDREKAAAKFREYFSKDILKLRLYEQQHGKCLYSGKEINLGRLNEKGYVEIDHALPFSRTWDDSFNNKVLVLGSENQNKGNQTPYEYFNGKDNSREWQEFKARVETSRFPRSKKQRILLQDGFKERNLNDTRYVNRFLCQFVADRMRLTGKGKKRVFASNGQITNLLRGFWGLRKVRAENDRHHALDAVVVACSTVAMQQKITRFVRYKEMNAFDGKTIDTGEVLHQKTHFPQPWEFFAQEVMIRVFGKPDGKPEFEEADTLEKLRTLLAEKLSSRPEAVHEYVTPLFVSRAPNRKMSGQGHMETVKSAKRLDEGVSVLRVPLTQLKLKDLEKMVNREREPKLYEALKARLEAHKDDPAKAFAEPFYKYDKAGNRTQQVKAVRVEQVQKTGVWVRNHNGIADNATMVRVDVFEKGDKYYLVPIYSWQVAKGILPDRAVVQGKDEEDWQLIDDSFNFKFSLHPNDLVEVITKKARMFGYFASCHRGTGNINIRIHDLDHKIGKNGILEGIGVKTALSFQKYQIDELGKEIRPCRLKKRPPVR 6klk A 1.76 BS01 URF A 1 H61 L64 F66 K150 F152 Y155 H183 M288 S289 D316 C318 N337 G338 H60 L63 F65 K149 F151 Y154 H182 M287 S288 D315 C317 N336 G337 3.5.2.2 Q9I676 31481233 SLLIRGATVVTHEESYRADVLCANGLIQAIGENLETPSGCDVLDGGGQYLMPGGIDPHTHMQLPFMGTVASEDFFSGTAAGLAGGTTSIIDFVIPNPRQSLLEAFHTWRGWAQKSAADYGFHVAITWWSDEVAREMGELVAQHGVNSFKHFMAYKNAIMAADDTLVASFERCLELGAVPTVHAENGELVFHLQQKLLAQGLTGPEAHPLSRPPQVEGEAASRAIRIAETLGTPLYLVHISSREALDEIAYARAKGQPVYGEVLAGHLLLDDSVYRHPDWATAAGYVMSPPFRPVEHQEALWRGLQSGNLHTTATDHCCFCAEQKAMGRDDFSKIPNGTAGIEDRMALLWDAGVNSGRLSMHEFVALTSTNTAKIFNLFPRKGAIRVGADADLVLWDPQGSRTLSAATHHQRVDFNIFEGRTVRGIPSHTISQGKLLWAAGDLRAEPGAGRYVERPAYPSVYEVLGRRAERQRPVAVER 6ko6 B 2.40 BS01 ANP B 1 G47 S50 V52 I65 K67 E113 V115 K157 H159 N160 M162 I173 D174 G43 S46 V48 I61 K63 E109 V111 K153 H155 N156 M158 I169 D170 A0A226BA59 31591414 RSVARVYANVNEKLGRSWWDYDNLVVQWGVQDNYEIVRKVGRGKYSEVFESIHLPTDSKCIVKVLKPVKKKKIKREIKILQNLAGGPNVVGLLDVVRDSQSKTPSIVTEYVNNTEFKTLYPKFSDFDVRYYIFELLKALDFCHSKGIMHRDVKPHNVMIDHEKRTLRLIDWGLAEFYHPGTEYNVRVASRYFKGPELLVDFQEYDYSLDMWSLGCMFASMIFRKEPFFHGHDNADQLVKIAKVLGTDELYTYLERYDIDLDAQFDDILGRYPRKPWSRFVSSENQRYISSEAIDFLDKLLRYDHQERLTAEEAKEHPYFEPVRQAAAQAS 6kzy A 2.30 BS01 CU A 1 E25 E60 H63 Q139 E24 E59 H62 Q138 1.16.3.1 D3JCC5 AQTQPRQNFHVESEAGINKQINMELYASYVYQSMYMYFDRDDVALPSFAKYFKHNSEEEREHAEKLMKYQNKRGGRIVLQDIQKPDLDEWGSPLEAMQTTLALEKSVNQALLDLHKIADKHGDAQMMDFLEGEYLKEQVDAIEEISDHITNLKRVGTGLGEYMYDKETM 6kzy A 2.30 BS02 CU A 2 D129 E132 D128 E131 1.16.3.1 D3JCC5 AQTQPRQNFHVESEAGINKQINMELYASYVYQSMYMYFDRDDVALPSFAKYFKHNSEEEREHAEKLMKYQNKRGGRIVLQDIQKPDLDEWGSPLEAMQTTLALEKSVNQALLDLHKIADKHGDAQMMDFLEGEYLKEQVDAIEEISDHITNLKRVGTGLGEYMYDKETM 6kzy B 2.30 BS02 CU B 1 E25 E60 H63 E23 E58 H61 1.16.3.1 D3JCC5 QTQPRQNFHVESEAGINKQINMELYASYVYQSMYMYFDRDDVALPSFAKYFKHNSEEEREHAEKLMKYQNKRGGRIVLQDIQKPDLDEWGSPLEAMQTTLALEKSVNQALLDLHKIADKHGDAQMMDFLEGEYLKEQVDAIEEISDHITNLKRVGTGLGEYMYDKETM 6l55 A 1.78 BS01 FE A 1 E25 E60 H63 V108 E23 E58 H61 V106 1.16.3.1 D3JCC5 QTQPRQNFHVESEAGINKQINMELYASYVYQSMYMYFDRDDVALPSFAKYFKHNSEEEREHAEKLMKYQNKRGGRIVLQDIQKPDLDEWGSPLEAMQTTLALEKSVNQALLDLHKIADKHGDAQMMDFLEGEYLKEQVDAIEEISDHITNLKRVGTGLGEYMYDKETMS 6l55 B 1.78 BS01 FE B 1 E25 E60 H63 V108 Q139 E23 E58 H61 V106 Q137 1.16.3.1 D3JCC5 QTQPRQNFHVESEAGINKQINMELYASYVYQSMYMYFDRDDVALPSFAKYFKHNSEEEREHAEKLMKYQNKRGGRIVLQDIQKPDLDEWGSPLEAMQTTLALEKSVNQALLDLHKIADKHGDAQMMDFLEGEYLKEQVDAIEEISDHITNLKRVGTGLGEYMYDKETMS 6mpb B 3.84 BS01 GLN B 1 S352 S353 A390 A429 G430 I431 P432 G435 D464 C467 T468 N471 S310 S311 A348 A387 G388 I389 P390 G393 D422 C425 T426 N429 Q15758 31580259 DQVRRCLRANLLVLLTVVAVVAGVALGLGVSGAGGALALGPERLSAFVFPGELLLRLLRMIILPLVVCSLIGGAASLDPGALGRLGAWALLFFLVTTLLASALGVGLALALQPGAASAAINASVGAAGSAENAPSKEVLDSFLDLARNIFPSNLVSAAFRSYSTTYEERNITGTRVKVPVGQEVEGMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLMMKCVEENNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVEGDALGAGLLQNYVDR 6mpb C 3.84 BS01 GLN C 1 S351 S352 S353 A390 I431 G435 D464 C467 T468 N471 S309 S310 S311 A348 I389 G393 D422 C425 T426 N429 Q15758 31580259 DQVRRCLRANLLVLLTVVAVVAGVALGLGVSGAGGALALGPERLSAFVFPGELLLRLLRMIILPLVVCSLIGGAASLDPGALGRLGAWALLFFLVTTLLASALGVGLALALQPGAASAAINASVGAAGSAENAPSKEVLDSFLDLARNIFPSNLVSAAFRSYSTTYEERNITGTRVKVPVGQEVEGMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLMMKCVEENNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVEGDALGAGLLQNYVDR 6mpb A 3.84 BS01 GLN A 1 S351 S353 A390 I431 P432 G435 D464 C467 T468 N471 S309 S311 A348 I389 P390 G393 D422 C425 T426 N429 Q15758 31580259 DQVRRCLRANLLVLLTVVAVVAGVALGLGVSGAGGALALGPERLSAFVFPGELLLRLLRMIILPLVVCSLIGGAASLDPGALGRLGAWALLFFLVTTLLASALGVGLALALQPGAASAAINASVGAAGSAENAPSKEVLDSFLDLARNIFPSNLVSAAFRSYSTTYEERNITGTRVKVPVGQEVEGMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLMMKCVEENNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCTVLNVEGDALGAGLLQNYVDR 6mwf A 1.75 BS02 SFY A 1 D10 H12 G35 H36 S37 H44 I59 F63 D65 F70 L78 D10 H12 G35 H36 S37 H44 I59 F63 D65 F70 L78 4.6.1.12 Q3JRA0 MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 6mwf C 1.75 BS02 SFY C 1 D10 H12 G35 H36 S37 H44 I59 F63 L78 D11 H13 G36 H37 S38 H45 I60 F64 L75 4.6.1.12 Q3JRA0 SMDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 6mwi B 1.75 BS02 EZL B 1 D10 H12 H44 I59 F63 S64 F70 D11 H13 H45 I60 F64 S65 F71 4.6.1.12 Q3JRA0 SMDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 6mwj A 2.05 BS02 AZM A 1 D10 H12 S37 H44 I59 G60 F63 S64 D65 F70 L78 D11 H13 S38 H45 I60 G61 F64 S65 D66 F71 L79 4.6.1.12 Q3JRA0 SMDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 6mwk A 1.80 BS02 K4Y A 1 D10 H12 G35 H36 S37 H44 I59 G60 F63 S64 D65 F70 L78 D11 H13 G36 H37 S38 H45 I60 G61 F64 S65 D66 F71 L79 4.6.1.12 Q3JRA0 SMDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 6mwk B 1.80 BS02 K4Y B 1 D10 H12 G35 H36 H44 I59 G60 F63 L78 D11 H13 G36 H37 H45 I60 G61 F64 L79 4.6.1.12 Q3JRA0 SMDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 6mwk C 1.80 BS02 K4Y C 1 D10 H12 G35 H36 H44 I59 F63 L78 D11 H13 G36 H37 H45 I60 F64 L79 4.6.1.12 Q3JRA0 SMDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVRE 6myo A 2.20 BS01 FAD A 1 V24 G25 A26 G27 G28 A29 T48 K49 L50 S55 H56 T57 A59 A60 Q61 G62 G63 Y176 F177 A178 A212 T213 G214 T224 D232 L263 H364 Y365 G396 E397 R408 A411 S413 L414 L417 V15 G16 A17 G18 G19 A20 T39 K40 L41 S46 H47 T48 A50 A51 Q52 G53 G54 Y167 F168 A169 A203 T204 G205 T215 D223 L254 H355 Y356 G387 E388 R399 A402 S404 L405 L408 1.3.5.1 F1NPJ4 TQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEDDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVIELENYGMPFSRTEEGKIYQRAFGGQSLQFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGTIHRFRAKNTVIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTIEIREGRGCGPEKDHVYLQLHHLPPQQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVITHVNGEDKVVPGLYACGEAASASVHGANRLGANSLLDLVVFGRACALTIAETCKPGEPVPSIKPNAGEESVANLDKLRFADGTIRTSEARLNMQKTMQSHAAVFRTGSILQEGCEKLSQIYRDLAHLKTFDRGIVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKLRIDEFDYSKPLQGQQKRPFEEHWRKHTLSYVDVKSGKVTLKYRPVIDRTLNEEDCSSVPPAIRSY 6myo D 2.20 BS02 HEM C 1 R14 L20 L24 L43 H46 G50 L51 R13 L19 L23 L42 H45 G49 L50 Q5ZIS0 SSKAASLHWTSERAVSALLLGLLPAAYLYPGPAVDYSLAAALTLHGHWGLGQVITDYVHGDTPIKVANTGLYVLSAITFTGLCYFNYYDVGICKAVAMLWSI 6myp A 2.10 BS03 BCT A 1 Y98 K375 E430 Y89 K366 E421 1.3.5.1 F1NPJ4 TQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEDDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVIELENYGMPFSRTEEGKIYQRAFGGQSLQFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGTIHRFRAKNTVIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTIEIREGRGCGPEKDHVYLQLHHLPPQQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVITHVNGEDKVVPGLYACGEAASASVHGANRLGANSLLDLVVFGRACALTIAETCKPGEPVPSIKPNAGEESVANLDKLRFADGTIRTSEARLNMQKTMQSHAAVFRTGSILQEGCEKLSQIYRDLAHLKTFDRGIVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKLRIDEFDYSKPLQGQQKRPFEEHWRKHTLSYVDVKSGKVTLKYRPVIDRTLNEEDCSSVPPAIRSY 6myp B 2.10 BS03 F3S B 1 C168 S170 Y178 C215 H216 T217 I218 M219 N220 C221 G232 I235 C161 S163 Y171 C208 H209 T210 I211 M212 N213 C214 G225 I228 1.3.5.1 Q9YHT2 TSRIKKFSIYRWDPDKPGDKPRMQTYEVDLNKCGPMVLDALIKIKNELDSTLTFRRSCREGICGSCAMNIAGGNTLACTKKIDPDLSKTTKIYPLPHMYVVKDLVPDLSNFYAQYKSIEPYLKKKDESKQGKEQYLQSIEDRQKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDYTEERLAQLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKE 6myp B 2.10 BS04 TTF C 1 P169 W173 H216 P162 W166 H209 1.3.5.1 Q9YHT2 TSRIKKFSIYRWDPDKPGDKPRMQTYEVDLNKCGPMVLDALIKIKNELDSTLTFRRSCREGICGSCAMNIAGGNTLACTKKIDPDLSKTTKIYPLPHMYVVKDLVPDLSNFYAQYKSIEPYLKKKDESKQGKEQYLQSIEDRQKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDYTEERLAQLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKE 6myp C 2.10 BS01 TTF C 1 I27 M36 S39 I40 R43 I26 M35 S38 I39 R42 1.3.5.1 D0VWW3 ATTAKEEMARFWEKNTKSSRPLSPHISIYKWSLPMAMSITHRGTGVALSLGVSLFSLAALLLPEQFPHYVAVVKSLSLSPALIYSAKFALVFPLSYHTWNGIRHLVWDMGKGFKLSQVEQSGVVVLILTLLSSAAIAAM 6myp D 2.10 BS01 HEM C 1 R14 L20 L24 L43 H46 G50 R13 L19 L23 L42 H45 G49 Q5ZIS0 SSKAASLHWTSERAVSALLLGLLPAAYLYPGPAVDYSLAAALTLHGHWGLGQVITDYVHGDTPIKVANTGLYVLSAITFTGLCYFNYYDVGICKAVAMLWSI 6myq B 1.97 BS04 9AU C 1 W173 I218 W166 I211 1.3.5.1 Q9YHT2 TSRIKKFSIYRWDPDKPGDKPRMQTYEVDLNKCGPMVLDALIKIKNELDSTLTFRRSCREGICGSCAMNIAGGNTLACTKKIDPDLSKTTKIYPLPHMYVVKDLVPDLSNFYAQYKSIEPYLKKKDESKQGKEQYLQSIEDRQKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDYTEERLAQLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKE 6myq C 1.97 BS02 9AU C 1 I27 M36 I40 I26 M35 I39 1.3.5.1 D0VWW3 ATTAKEEMARFWEKNTKSSRPLSPHISIYKWSLPMAMSITHRGTGVALSLGVSLFSLAALLLPEQFPHYVAVVKSLSLSPALIYSAKFALVFPLSYHTWNGIRHLVWDMGKGFKLSQVEQSGVVVLILTLLSSAAIAAM 6myq D 1.97 BS01 HEM C 1 R14 L20 L43 H46 G50 L51 R13 L19 L42 H45 G49 L50 Q5ZIS0 SSKAASLHWTSERAVSALLLGLLPAAYLYPGPAVDYSLAAALTLHGHWGLGQVITDYVHGDTPIKVANTGLYVLSAITFTGLCYFNYYDVGICKAVAMLWSI 6myt B 2.27 BS04 AT5 C 1 P169 S170 W172 W173 H216 I218 P162 S163 W165 W166 H209 I211 1.3.5.1 Q9YHT2 TSRIKKFSIYRWDPDKPGDKPRMQTYEVDLNKCGPMVLDALIKIKNELDSTLTFRRSCREGICGSCAMNIAGGNTLACTKKIDPDLSKTTKIYPLPHMYVVKDLVPDLSNFYAQYKSIEPYLKKKDESKQGKEQYLQSIEDRQKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDYTEERLAQLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKE 6myt D 2.27 BS02 HEM C 1 R14 L20 L21 L24 L43 H46 G50 V54 R13 L19 L20 L23 L42 H45 G49 V53 Q5ZIS0 SSKAASLHWTSERAVSALLLGLLPAAYLYPGPAVDYSLAAALTLHGHWGLGQVITDYVHGDTPIKVANTGLYVLSAITFTGLCYFNYYDVGICKAVAMLWSI 6myz A 1.66 BS01 K7D A 1 Y204 H263 K265 N283 G458 S459 P461 H493 K495 W590 Y43 H102 K104 N122 G292 S293 P295 H327 K329 W421 3.1.4.- Q9NUW8 NPFQFYLTRVSGVKPKYNSGALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPILLVHGDKREAKAHLHAQAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSPLYPRIADGTHKSGESPTHFKADLISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIGSTPGRFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEFKESMLTLGKESSSVPLYLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQNWLHSYFHKWSAETSGRSNAMPHIKTYMRPSPDFSKIAWFLVTSANLSKAAWGALEKNGTQLMIRSYELGVLFLPSAFGLDSFKVKQKFFAGPMATFPVPYDLPPELYGSKDRPWIWNIPYVKAPDTHGNMWVP 6mz0 A 1.97 BS01 K7A A 1 H263 K265 N283 S459 P461 H493 K495 N516 H102 K104 N122 S293 P295 H327 K329 N350 3.1.4.- Q9NUW8 NPFQFYLTRVSGVKPKYNSGALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPILLVHGDKREAKAHLHAQAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSPLYPRIADGTHKSGESPTHFKADLISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIGSTPGRFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEFKESMLTLGKESSSVPLYLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQNWLHSYFHKWSAETSGRSNAMPHIKTYMRPSPDFSKIAWFLVTSANLSKAAWGALEKNGTQLMIRSYELGVLFLPSAFGLDSFKVKQKFFAPMATFPVPYDLPPELYGSKDRPWIWNIPYVKAPDTHGNMWVP 6mz0 B 1.97 BS01 K7A B 1 H263 K265 N283 S399 S459 P461 H493 K495 N516 H102 K104 N122 S238 S293 P295 H327 K329 N350 3.1.4.- Q9NUW8 NPFQFYLTRVSGVKPKYNSGALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPILLVHGDKREAKAHLHAQAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSPLYPRIADGTHKSGESPTHFKADLISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIGSTPGRFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEFKESMLTLGKESSSVPLYLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQNWLHSYFHKWSAETSGRSNAMPHIKTYMRPSPDFSKIAWFLVTSANLSKAAWGALEKNGTQLMIRSYELGVLFLPSAFGLDSFKVKQKFFAGPMATFPVPYDLPPELYGSKDRPWIWNIPYVKAPDTHGNMWVP 6n7y F 2.00 BS01 KFA F 1 K57 N59 S205 F206 F239 Q242 L246 L344 K347 K45 N47 S191 F192 F225 Q228 L232 L330 K333 2.5.1.10,2.5.1.1 P14324 31577901 YAQEKQDFVQHFSQIVRVLTEGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 6n7z F 2.55 BS01 KF7 F 1 K57 N59 R60 S205 F206 F239 D243 L246 K44 N46 R47 S191 F192 F225 D229 L232 2.5.1.10,2.5.1.1 P14324 31577901 AQEKQDFVQHFSQIVRVLTEGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 6n82 F 2.00 BS01 YF7 F 1 K57 N59 S205 F206 F239 D243 T255 L344 K50 N52 S196 F197 F230 D234 T246 L335 2.5.1.10,2.5.1.1 P14324 31577901 DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 6n82 F 2.00 BS02 YF7 F 2 L315 E318 E319 Y322 L342 A345 R346 Y349 K350 L306 E309 E310 Y313 L333 A336 R337 Y340 K341 2.5.1.10,2.5.1.1 P14324 31577901 DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 6n83 F 2.00 BS01 YL6 F 1 K57 N59 R60 T63 S205 F206 F239 Q242 D243 L344 K347 I348 K350 K48 N50 R51 T54 S196 F197 F230 Q233 D234 L335 K338 I339 K341 2.5.1.10,2.5.1.1 P14324 31577901 SDVYAQEKQDFVQHFSQIVRVLTEGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 6n90 B 1.76 BS01 TEW B 1 S71 G72 S73 R78 S71 G72 S73 R76 A9CID9 MKLVWTLSSWDDYEFWQRTDARMVEKINDLIRNAKRTPFAGLGKPEPLKGDMAGYWSRRITAEHRFVYRVSGSGQRLEVIQCRFHY 6nwc A 2.35 BS01 L6P A 1 K56 L79 L83 S88 I106 H111 L113 Y116 V156 L159 N163 K32 L55 L59 S64 I82 H87 L89 Y92 V132 L135 N139 Q8H1R0 31649167 SQCSSTLVKHIKAPLHLVWSIVRRFDEPQKYKPFISRCVVQGKKLEVGSVREVDLKSGLPATKSTEVLEILDDNEHILGIRIVGGDHRLKNYSSTISLHSETIDGKTGTLAIESFVVDVPEGNTKEETCFFVEALIQCNLNSLADVTERLQAESM 6nzd F 3.60 BS01 GDP F 1 K15 S16 G17 S18 G19 K20 T21 H127 K128 D130 S163 I164 W165 K6 S7 G8 S9 G10 K11 T12 H67 K68 D70 S103 I104 W105 Q7L523 VLLMGKSGSGKTSMRSIIFAVLNLWDVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECACFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAQIIEADEVLLFERATFLVISHYQRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFTSNTYVMVVMSDPSIPSAATLINIRNARK 6nzd G 3.60 BS01 L8S G 1 R70 R71 S72 G73 K74 S75 S76 T90 L91 S95 T96 P118 G119 H178 K179 N181 I220 R9 R10 S11 G12 K13 S14 S15 T29 L30 S34 T35 P57 G58 H117 K118 N120 I159 Q9HB90 PRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQMDFFDPTFDYEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVNPDMNFEVFIHKVNGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKLIPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVSCIYGLAYDKESMAIIKLNNTTVLYLKEVTKFLALVCILREESFERKGLIDYNFHCFRKAIHEVF 6nzd H 3.60 BS01 GDP F 1 R122 V126 R42 V46 Q8NFG4 NAIVALCHFCELHGPRTLFCTEVIKYVSHQHPSHPQLFSIVRQACVRSLSCEVCPGREGPIFFGDEQHGFVFSHTFFIKDSLARGFQRWYSIITIMMDRIYLINSWPFLLGKVRGIIDELQGKALKVFEAEQFGCPQRAQRMNTAFTPFLHQRNGNAARSLTSLTSDDNLWACLHTSFAWLLKACGSRLPVFKSLRHMRQVLGAPSFRMLAWHVLMGNQVIWKSRDVDLVQSAFEVLRTMLPVGCVRIIPYSSQYEEAYRCNFLGLSPHVQIPPHVLSSEFAVIVEVHAQSLSKYEFVVTSGSPVAADRVGPTILNKIEAALTNQNLSVDVVDQCLVCLKEEWMNKVKVLFKFTKRPKEDTQKLLSILGASEEDNVKLLKFWMTGLS 6o4i A 1.75 BS01 UN1 A 1 E121 N167 F168 W175 R301 C302 T303 S460 G461 A462 F468 E119 N165 F166 W173 R299 C300 T301 S458 G459 A460 F466 1.2.1.31,1.2.1.3,1.2.1.8 P49419 31652343 TLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTDTFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ 6o4k A 2.06 BS01 NAD A 1 I163 T164 K190 A192 P193 A227 G230 T231 F244 T245 G246 S247 V250 V254 I161 T162 K188 A190 P191 A225 G228 T229 F242 T243 G244 S245 V248 V252 1.2.1.31,1.2.1.3,1.2.1.8 P49419 31652343 TLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTQTFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ 6o4k B 2.06 BS01 NAD B 1 I163 T164 A165 F166 K190 A192 P193 A227 G230 T231 F244 T245 G246 S247 V250 V254 F401 I161 T162 A163 F164 K188 A190 P191 A225 G228 T229 F242 T243 G244 S245 V248 V252 F399 1.2.1.31,1.2.1.3,1.2.1.8 P49419 31652343 TLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTQTFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ 6o4k E 2.06 BS01 NAD E 1 I163 T164 K190 G191 A192 P193 A227 G230 T231 F244 G246 S247 V250 I161 T162 K188 G189 A190 P191 A225 G228 T229 F242 G244 S245 V248 1.2.1.31,1.2.1.3,1.2.1.8 P49419 31652343 TLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTQTFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ 6o4k G 2.06 BS01 NAD G 1 I163 T164 F166 K190 P193 A227 G230 T231 F244 T245 G246 S247 V250 V254 I161 T162 F164 K188 P191 A225 G228 T229 F242 T243 G244 S245 V248 V252 1.2.1.31,1.2.1.3,1.2.1.8 P49419 31652343 TLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTQTFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIK 6o4l A 1.85 BS01 NAD A 1 I163 T164 A165 F166 K190 A192 P193 A227 G230 T231 F244 T245 G246 S247 V250 V254 G270 G271 C302 D399 F401 I161 T162 A163 F164 K188 A190 P191 A225 G228 T229 F242 T243 G244 S245 V248 V252 G268 G269 C300 D397 F399 1.2.1.31,1.2.1.3,1.2.1.8 P49419 31652343 TLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTDTFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKF 6o67 A 2.52 BS01 LO7 A 1 G284 C285 F287 I341 S342 M364 G67 C68 F70 I124 S125 M147 P37231 31611383 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYK 6o67 A 2.52 BS02 KNA A 1 I262 K263 I341 S342 I56 K57 I124 S125 P37231 31611383 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYK 6o68 A 2.78 BS01 LO4 A 1 G284 C285 R288 I341 M364 G69 C70 R73 I126 M149 P37231 31611383 ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDL 6oag F 2.30 BS01 M2Y F 1 K57 N59 S205 F206 F239 D243 L344 K50 N52 S198 F199 F232 D236 L337 2.5.1.10,2.5.1.1 P14324 31577901 DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 6oag F 2.30 BS02 M2Y F 2 E318 Y322 M326 R346 Y349 K350 E311 Y315 M319 R339 Y342 K343 2.5.1.10,2.5.1.1 P14324 31577901 DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 6oah F 2.20 BS01 M2V F 1 N59 R60 S205 F206 F239 Q242 L344 K347 I348 K350 N52 R53 S198 F199 F232 Q235 L337 K340 I341 K343 2.5.1.10,2.5.1.1 P14324 31577901 SDVYAQEKQDFVQHFSQIVRVLTEEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 6oah F 2.20 BS02 M2V F 2 A312 E318 E319 K350 A305 E311 E312 K343 2.5.1.10,2.5.1.1 P14324 31577901 SDVYAQEKQDFVQHFSQIVRVLTEEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 6oim A 1.65 BS02 MOV A 1 V9 G10 C12 K16 P34 A59 G60 Q61 E62 E63 R68 M72 H95 Y96 Q99 V103 V10 G11 C13 K17 P35 A60 G61 Q62 E63 E64 R69 M73 H96 Y97 Q100 V104 P01116 GMTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEK 6oy3 B 4.00 BS01 CA B 1 N448 E452 E506 E535 N383 E387 E432 E461 C7Z7K1 SNFGVDFVIHYKVPAAERDEAEAGFVQLIRALTTVGLATEVRHGENESLLVFVKVASPDLFAKQVYRARLGDWLHGVRVSAPIAQALQDEPVVEAERLRLIYLMITKPHNWKHVESIFPLHSHSFNKEWIKKWSSKYTLEQTDIDNIRDKFGESVAFYFAFLRSYFRFLVIPSAFGFGAWLLLGQFSYLYALLCGLWSVVFFEYWKKQEVDLAVQWGVRGVSSIQQSRPEFEWEHEAVKVYPPMKRVKTQLLQIPFALACVVAAGALIVTCNSLEVFINEVGKQYLGFLPTIFLVIGTPTISGVLMGAAEKLNAMENYATVDAHDAALIQKQFVLNFMTSYMALFFTAFVYIPFGHILHPFQINPARISNQMFYFTVTAQIVNFATEVVVPYIKQQAFQKAKQDHEEEAEFLQRVREECTLEEYDVSGDYREMVMQFGYVAMFSVAWPLAACCFLVNNWVELRSDALKIAISSRRPIPWRTDSIGPWLTALSFLSWLGSITSSAIVYLCSASPLKAWGLLLSILFAEHFYLVVQLAVRFVLSKLDSPGLQKERKERFQTKKRLLQENLGWQRQRGMQETIEIGRRMIEQQLAAG 6oy3 B 4.00 BS02 CA B 2 N448 E452 D503 E506 E535 N383 E387 D429 E432 E461 C7Z7K1 SNFGVDFVIHYKVPAAERDEAEAGFVQLIRALTTVGLATEVRHGENESLLVFVKVASPDLFAKQVYRARLGDWLHGVRVSAPIAQALQDEPVVEAERLRLIYLMITKPHNWKHVESIFPLHSHSFNKEWIKKWSSKYTLEQTDIDNIRDKFGESVAFYFAFLRSYFRFLVIPSAFGFGAWLLLGQFSYLYALLCGLWSVVFFEYWKKQEVDLAVQWGVRGVSSIQQSRPEFEWEHEAVKVYPPMKRVKTQLLQIPFALACVVAAGALIVTCNSLEVFINEVGKQYLGFLPTIFLVIGTPTISGVLMGAAEKLNAMENYATVDAHDAALIQKQFVLNFMTSYMALFFTAFVYIPFGHILHPFQINPARISNQMFYFTVTAQIVNFATEVVVPYIKQQAFQKAKQDHEEEAEFLQRVREECTLEEYDVSGDYREMVMQFGYVAMFSVAWPLAACCFLVNNWVELRSDALKIAISSRRPIPWRTDSIGPWLTALSFLSWLGSITSSAIVYLCSASPLKAWGLLLSILFAEHFYLVVQLAVRFVLSKLDSPGLQKERKERFQTKKRLLQENLGWQRQRGMQETIEIGRRMIEQQLAAG 6p5r A 2.45 BS01 GDP A 1 P444 Y527 R529 L604 Y605 Q606 R614 V615 Y619 R686 Y690 R694 P53 Y125 R127 L202 Y203 Q204 R212 V213 Y217 R284 Y288 R292 B6SBM0 PRGSHMDDALRGELASTIQLEKLSHPPARFDLLTSFVYKWQTKAALARKVSGPMREWAAELKYRTGVHIELEPTYPERLSENATQWGAYETADDVDITVYLFGSERGIFNCHKLMEAAIQQDPVYVRLGIFRRLANSSEVEWLMLRRINRELRPPDIPPISLKLPGKWTLLYERYKEAAIRTLWEETGITVDASNVYPTGHLYQTVPQYYWRVPVRYFVAEVPSDIRVEGPQVVPLQYMRNWDARLLRQSPDPIDRAWAQLADPATGCAWMKASMIDQLQKPLRGDNYMAIRYTPPPYSNLQEVVGLG 6pbe A 3.78 BS01 O6S A 1 E294 L402 E403 D406 Y415 L421 H426 I429 Y467 F468 M603 R606 E260 L368 E369 D372 Y381 L387 H392 I395 Y433 F434 M569 R572 Q9XSM3 31647410 WEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHD 6pbe A 3.78 BS02 O6S A 2 F487 L490 M491 C494 W495 F453 L456 M457 C460 W461 Q9XSM3 31647410 WEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHD 6pbf A 4.20 BS01 O6V A 1 L490 M491 C494 L451 M452 C455 Q9XSM3 31647410 WEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHH 6pcp A 3.20 BS01 OA7 A 1 H23 R26 H12 R15 A0A0T7MD48 PGPYHFSEQVGHLLRRAYQRHVAIFQQTIPDSKLTAAQFVVLCALRDQGACSLVDVVKATAIDQATVRGVIERLKARKLLAVSHDPADRRKVLVTLTPDGRALVEEMVPFAEQITQSTFGGLNPAERVAIVYLLRKMSDA 6pcp A 3.20 BS02 OA7 A 2 H32 F36 V51 H21 F25 V40 A0A0T7MD48 PGPYHFSEQVGHLLRRAYQRHVAIFQQTIPDSKLTAAQFVVLCALRDQGACSLVDVVKATAIDQATVRGVIERLKARKLLAVSHDPADRRKVLVTLTPDGRALVEEMVPFAEQITQSTFGGLNPAERVAIVYLLRKMSDA 6pcp B 3.20 BS02 OA7 C 1 H32 F36 H21 F25 A0A0T7MD48 PGPYHFSEQVGHLLRRAYQRHVAIFQQTIPDSKLTAAQFVVLCALRDQGACSLVDVVKATAIDQATVRGVIERLKARKLLAVSHDRRKVLVTLTPDGRALVEEMVPFAEQITQSTFGGLNPAERVAIVYLLRKMS 6pcp C 3.20 BS01 OA7 B 1 H32 F36 A47 V51 H20 F24 A35 V39 A0A0T7MD48 GPYHFSEQVGHLLRRAYQRHVAIFQQTIPDSKLTAAQFVVLCALRDQGACSLVDVVKATAIDQATVRGVIERLKARKLLAVSHDPADRRKVLVTLTPDGRALVEEMVPFAEQITQSTFGGLNPAERVAIVYLLRKMSDAD 6pcp D 3.20 BS02 OA7 A 3 Y15 H23 R26 Y3 H11 R14 A0A0T7MD48 GPYHFSEQVGHLLRRAYQRHVAIFQQTIPDSKLTAAQFVVLCALRDQGACSLVDVVKATAIDQATVRGVIERLKARKLLAVSHDPADRRKVLVTLTPDGRALVEEMVPFAEQITQSTFGGLNPAERVAIVYLLRKMSDA 6pcp E 3.20 BS01 OA7 E 1 Y15 G22 H23 R26 Y3 G10 H11 R14 A0A0T7MD48 GPYHFSEQVGHLLRRAYQRHVAIFQQTIPDSKLTAAQFVVLCALRDQGACSLVDVVKATAIDQATVRGVIERLKARKLLAVSHDPADRRKVLVTLTPDGRALVEEMVPFAEQITQSTFGGLNPAERVAIVYLLRKMSDAD 6pcp E 3.20 BS02 OA7 F 1 H32 A47 V51 H20 A35 V39 A0A0T7MD48 GPYHFSEQVGHLLRRAYQRHVAIFQQTIPDSKLTAAQFVVLCALRDQGACSLVDVVKATAIDQATVRGVIERLKARKLLAVSHDPADRRKVLVTLTPDGRALVEEMVPFAEQITQSTFGGLNPAERVAIVYLLRKMSDAD 6pcp F 3.20 BS01 OA7 E 1 H32 F36 V51 I125 H21 F25 V40 I114 A0A0T7MD48 PGPYHFSEQVGHLLRRAYQRHVAIFQQTIPDSKLTAAQFVVLCALRDQGACSLVDVVKATAIDQATVRGVIERLKARKLLAVSHDPADRRKVLVTLTPDGRALVEEMVPFAEQITQSTFGGLNPAERVAIVYLLRKMSDA 6pcp F 3.20 BS02 OA7 F 1 G22 H23 R26 G11 H12 R15 A0A0T7MD48 PGPYHFSEQVGHLLRRAYQRHVAIFQQTIPDSKLTAAQFVVLCALRDQGACSLVDVVKATAIDQATVRGVIERLKARKLLAVSHDPADRRKVLVTLTPDGRALVEEMVPFAEQITQSTFGGLNPAERVAIVYLLRKMSDA 6peu A 1.95 BS01 III M 1 Y66 E82 R86 Y143 P144 T145 R151 G152 N153 T154 R177 L245 C246 V247 E265 Q268 S269 R278 R279 R284 I291 L296 H300 T366 I367 Y66 E82 R86 Y143 P144 T145 R151 G152 N153 T154 R177 L245 C246 V247 E265 Q268 S269 R278 R279 R284 I291 L296 H300 T366 I367 Q58494 31139720 MDIKYKLASYRICSPEETFEKIQEALKKIETVEIKNIQHLDKVNIPVYYLKRRVVVDGKEGIAIHYGKGANDIQAKVSACMEAIERFSASYDKNKVKEKPDNPINVEDLILPQYADKNVKEWVEGIDIINNETIDVPADAVFYPTSGKLFRGNTNGLASGNNLDEAILHATLEIIERDAWSLADLARKIPTKINPEDAKNPLIHELIEKYEKAGVKIILKDLTSEFEIPVVAAISDDLSKNPLMLCVGVGCHLHPEIAILRALTEVAQSRASQLHGFRRDAKLREEFTSKIPYERLKRIHRKWFEFEGEINIADMPNNARYDLKKDLKFIKDKLSEFGFDKLIYVDLNKVGVDAVRVIIPKMEVYTIDRDRLSRRAFERVKKLY 6peu A 1.95 BS02 ATP A 1 R11 K68 V77 S78 M81 E82 E85 A158 S159 N161 E165 H169 E173 E176 R177 V249 E265 R11 K68 V77 S78 M81 E82 E85 A158 S159 N161 E165 H169 E173 E176 R177 V249 E265 Q58494 31139720 MDIKYKLASYRICSPEETFEKIQEALKKIETVEIKNIQHLDKVNIPVYYLKRRVVVDGKEGIAIHYGKGANDIQAKVSACMEAIERFSASYDKNKVKEKPDNPINVEDLILPQYADKNVKEWVEGIDIINNETIDVPADAVFYPTSGKLFRGNTNGLASGNNLDEAILHATLEIIERDAWSLADLARKIPTKINPEDAKNPLIHELIEKYEKAGVKIILKDLTSEFEIPVVAAISDDLSKNPLMLCVGVGCHLHPEIAILRALTEVAQSRASQLHGFRRDAKLREEFTSKIPYERLKRIHRKWFEFEGEINIADMPNNARYDLKKDLKFIKDKLSEFGFDKLIYVDLNKVGVDAVRVIIPKMEVYTIDRDRLSRRAFERVKKLY 6peu A 1.95 BS03 MG A 1 E176 V249 E265 E176 V249 E265 Q58494 31139720 MDIKYKLASYRICSPEETFEKIQEALKKIETVEIKNIQHLDKVNIPVYYLKRRVVVDGKEGIAIHYGKGANDIQAKVSACMEAIERFSASYDKNKVKEKPDNPINVEDLILPQYADKNVKEWVEGIDIINNETIDVPADAVFYPTSGKLFRGNTNGLASGNNLDEAILHATLEIIERDAWSLADLARKIPTKINPEDAKNPLIHELIEKYEKAGVKIILKDLTSEFEIPVVAAISDDLSKNPLMLCVGVGCHLHPEIAILRALTEVAQSRASQLHGFRRDAKLREEFTSKIPYERLKRIHRKWFEFEGEINIADMPNNARYDLKKDLKFIKDKLSEFGFDKLIYVDLNKVGVDAVRVIIPKMEVYTIDRDRLSRRAFERVKKLY 6peu B 1.95 BS02 ATP B 1 R11 K68 Q74 V77 S78 M81 E85 A158 S159 N161 E165 H169 E173 E176 R177 V249 E265 R11 K68 Q74 V77 S78 M81 E85 A158 S159 N161 E165 H169 E173 E176 R177 V249 E265 Q58494 31139720 MDIKYKLASYRICSPEETFEKIQEALKKIETVEIKNIQHLDKVNIPVYYLKRRVVVDGKEGIAIHYGKGANDIQAKVSACMEAIERFSASYDKNKVKEKPDNPINVEDLILPQYADKNVKEWVEGIDIINNETIDVPADAVFYPTSGKLFRGNTNGLASGNNLDEAILHATLEIIERDAWSLADLARKIPTKINPEDAKNPLIHELIEKYEKAGVKIILKDLTSEFEIPVVAAISDDLSKNPLMLCVGVGCHLHPEIAILRALTEVAQSRASQLHGFRRDAKLREEFTSKIPYERLKRIHRKWFEFEGEINIADMPNNARYDLKKDLKFIKDKLSEFGFDKLIYVDLNKVGVDAVRVIIPKMEVYTIDRDRLSRRAFERVKKLYY 6peu C 1.95 BS02 ATP C 1 R11 K68 Q74 V77 S78 M81 E82 E85 A158 S159 N161 E165 H169 E173 E176 R177 V249 R261 E265 R10 K67 Q73 V76 S77 M80 E81 E84 A157 S158 N160 E164 H168 E172 E175 R176 V248 R260 E264 Q58494 31139720 DIKYKLASYRICSPEETFEKIQEALKKIETVEIKNIQHLDKVNIPVYYLKRRVVVDGKEGIAIHYGKGANDIQAKVSACMEAIERFSASYDKNKVKEKPDNPINVEDLILPQYADKNVKEWVEGIDIINNETIDVPADAVFYPTSGKLFRGNTNGLASGNNLDEAILHATLEIIERDAWSLADLARKIPTKINPEDAKNPLIHELIEKYEKAGVKIILKDLTSEFEIPVVAAISDDLSKNPLMLCVGVGCHLHPEIAILRALTEVAQSRASQLHGFRRDAKLREEFTSKIPYERLKRIHRKWFEFEGEINIADMPNNARYDLKKDLKFIKDKLSEFGFDKLIYVDLNKVGVDAVRVIIPKMEVYTIDRDRLSRRAFERVKKLY 6pka A 2.25 BS01 III H 1 D27 I29 Y61 Y63 Q89 I93 L115 M190 D14 I16 Y48 Y50 Q76 I80 L102 M177 3.4.21.92 Q2G036 31588734 IPTVYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVP 6pka A 2.25 BS02 III U 1 V45 L49 A53 T80 H83 V32 L36 A40 T67 H70 3.4.21.92 Q2G036 31588734 IPTVYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVP 6ple A 2.50 BS01 BLA A 1 N7 I9 L19 R22 F23 A27 H28 T55 W57 F63 W66 H75 H78 P82 V83 A84 L89 N6 I8 L18 R21 F22 A26 H27 T54 W56 F62 W65 H74 H77 P81 V82 A83 L88 1.14.99.57 P9WKH3 31638374 PVVKINAIEVPAGAGPELEKRFAHSAHAVENSPGFLGFQLLRPVKGEERYFVVTHWESDEAFQAWANGPAIAAHAGHRANPVATGASLLEFEVVLD 6ple A 2.50 BS02 BLA A 2 A67 A71 R79 P82 A84 G86 A87 S88 L89 A66 A70 R78 P81 A83 G85 A86 S87 L88 1.14.99.57 P9WKH3 31638374 PVVKINAIEVPAGAGPELEKRFAHSAHAVENSPGFLGFQLLRPVKGEERYFVVTHWESDEAFQAWANGPAIAAHAGHRANPVATGASLLEFEVVLD 6ple A 2.50 BS03 BLA B 1 I72 R79 T85 I71 R78 T84 1.14.99.57 P9WKH3 31638374 PVVKINAIEVPAGAGPELEKRFAHSAHAVENSPGFLGFQLLRPVKGEERYFVVTHWESDEAFQAWANGPAIAAHAGHRANPVATGASLLEFEVVLD 6ple B 2.50 BS02 BLA B 2 A67 A71 R79 P82 A84 A87 S88 L89 A66 A70 R78 P81 A83 A86 S87 L88 1.14.99.57 P9WKH3 31638374 PVVKINAIEVPAGAGPELEKRFAHSAHAVENSPGFLGFQLLRPVKGEERYFVVTHWESDEAFQAWANGPAIAAHAGHRANPVATGASLLEFEVVLD 6ple B 2.50 BS03 BLA B 3 N7 I9 R22 F23 A27 H28 T55 W66 H75 H78 P82 V83 A84 L89 N6 I8 R21 F22 A26 H27 T54 W65 H74 H77 P81 V82 A83 L88 1.14.99.57 P9WKH3 31638374 PVVKINAIEVPAGAGPELEKRFAHSAHAVENSPGFLGFQLLRPVKGEERYFVVTHWESDEAFQAWANGPAIAAHAGHRANPVATGASLLEFEVVLD 6pmd A 2.21 BS01 III H 1 R23 L24 D27 I29 Y61 Y63 Q89 I91 F113 M190 R13 L14 D17 I19 Y51 Y53 Q79 I81 F103 M180 3.4.21.92 Q2G036 31588734 LIPTVIAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPET 6pmd E 2.21 BS01 III P 1 V45 L49 Q52 A53 T80 H83 V34 L38 Q41 A42 T69 H72 3.4.21.92 Q2G036 31588734 LIPTVIYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPE 6pmd E 2.21 BS02 III Q 1 R23 L24 D27 I29 Y61 Y63 Q89 I91 L115 M190 R12 L13 D16 I18 Y50 Y52 Q78 I80 L104 M179 3.4.21.92 Q2G036 31588734 LIPTVIYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPE 6pmd F 2.21 BS02 III R 1 R23 D27 I29 Y61 Y63 Q89 I91 I93 F113 M190 R12 D16 I18 Y50 Y52 Q78 I80 I82 F102 M179 3.4.21.92 Q2G036 31588734 LIPTVIYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVP 6pmd M 2.21 BS02 III X 1 L24 D27 I29 Y61 Y63 Q89 I91 F113 L115 L12 D15 I17 Y49 Y51 Q77 I79 F101 L103 3.4.21.92 Q2G036 31588734 LIPTVYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPE 6pmd N 2.21 BS01 III X 1 L49 F50 Q52 A53 T80 H83 L38 F39 Q41 A42 T69 H72 3.4.21.92 Q2G036 31588734 LIPTVIYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPE 6pmd T 2.21 BS01 III Y 1 L49 Q52 T80 H83 L37 Q40 T68 H71 3.4.21.92 Q2G036 31588734 LIPTVYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPE 6pmd T 2.21 BS02 III Z 1 R23 L24 D27 I29 Y61 Y63 Q89 I91 M190 R11 L12 D15 I17 Y49 Y51 Q77 I79 M178 3.4.21.92 Q2G036 31588734 LIPTVYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPE 6pmf A 1.95 BS01 LD9 A 1 H32 F36 P163 T168 M171 H32 F36 P163 T168 M171 P0AEG4 31635355 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 6pml A 2.00 BS01 PEG A 1 K55 M56 T57 M80 L134 K55 M56 T57 M80 L134 P0AEG4 31635355 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 6pml A 2.00 BS02 OR4 A 1 H32 F36 P151 P163 T168 M171 F174 H32 F36 P151 P163 T168 M171 F174 P0AEG4 31635355 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 6poh A 1.67 BS01 OVG A 1 H32 F36 G149 V150 P163 T168 F174 H32 F36 G149 V150 P163 T168 F174 P0AEG4 31635355 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 6poi A 1.77 BS01 OVS A 1 H32 F36 P163 Q164 T168 M171 F174 H32 F36 P163 Q164 T168 M171 F174 P0AEG4 31635355 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 6poq A 1.80 BS01 OVJ A 1 H32 Q35 P151 P163 T168 H32 Q35 P151 P163 T168 P0AEG4 31635355 AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEK 6pvu A 1.49 BS01 P0S A 1 K7 Q11 H12 R39 K41 H119 F120 K7 Q11 H12 R39 K41 H119 F120 4.6.1.18 P61823 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 6pvu B 1.49 BS01 P0S B 1 K7 Q11 H12 K41 H119 F120 K7 Q11 H12 K41 H119 F120 4.6.1.18 P61823 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 6pvv A 1.65 BS01 5FA A 1 K7 Q11 H12 K41 C65 N67 Q69 N71 A109 E111 H119 F120 K7 Q11 H12 K41 C65 N67 Q69 N71 A109 E111 H119 F120 4.6.1.18 P61823 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 6pvx A 1.55 BS02 U5F A 2 K7 R10 Q11 C65 N67 Q69 N71 A109 E111 V118 H119 K7 R10 Q11 C65 N67 Q69 N71 A109 E111 V118 H119 4.6.1.18 P61823 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 6pvx B 1.55 BS01 U5F B 1 K7 R10 Q11 H12 L35 R39 K41 V43 N44 T45 H119 F120 K7 R10 Q11 H12 L35 R39 K41 V43 N44 T45 H119 F120 4.6.1.18 P61823 KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV 6pw3 C 2.34 BS01 GTG C 1 S843 Y844 E847 R879 S882 Y883 E886 Y911 E914 K915 A918 F919 Y922 S47 Y48 E51 R83 S86 Y87 E90 Y115 E118 K119 A122 F123 Y126 Q6PKG0 HPSHELLKENGFTQHVYHKYRRRCLNERKRLGIGQSQEMNTLFRFWSYFLEDHFNKKMYEEFKQLALEDAKEGYRYGLECLFRYYSYGLEKKFRLDIFKDFQEETVKDYEAGQLYGLEKFWAFLKYSKAKNLDIDPKLQEYLGKFRRLE 6pw3 A 2.34 BS01 MG A 1 R871 E875 Y911 R76 E80 Y116 Q6PKG0 QHPSHELLKENGFTQHVYHKYRRRCLNERKRLGIGQSQEMNTLFRFWSYFLEDHFNKKMYEEFKQLALEDAKEGYRYGLECLFRYYSYGLEKKFRLDIFKDFQEETVKDYEAGQLYGLEKFWAFLKYSLDIDPKLQEYLGKFRR 6pw3 B 2.34 BS01 GTG B 1 R840 S843 Y844 E847 R879 Y880 Y883 Y911 E914 K915 R42 S45 Y46 E49 R81 Y82 Y85 Y113 E116 K117 Q6PKG0 HPSHELLKEFTQHVYHKYRRRCLNERKRLGIGQSQEMNTLFRFWSYFLEDHFNKKMYEEFKQLALEDAKEGYRYGLECLFRYYSYGLEKKFRLDIFKDFQEETVKDYEAGQLYGLEKFWAFLKYSNLDIDPKLQEYLGKF 6qb4 A 2.38 BS01 HVN A 1 H224 L235 M250 V253 R263 L267 F270 G271 H45 L56 M71 V74 R84 L88 F91 G92 Q07820 DDLYRQSLEIISRYLREQATGSKDAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHV 6qep A 2.60 BS01 MN A 1 G1274 E1276 D1322 W1325 D1442 G935 E937 D983 W986 D1103 31645583 VASETLKTKKMEVQIKKNFPSVLQYTMTDGKVMYGQSKDVRTVEINGTNIELGDDDVTFKKVSDTEATYTLKVKDEAKKIDAVITVQITVKANQLHLNVTKIKNNLSEGIPEGNGVEENAIQTLSFPNQSLVSVRSSQENAQFTGARMSSNTQKPGDTNFAVTEDTNVTDSDYTYGFISGAGLSAGLWSNSEHDGTYVAAPVRGGSQNTRVYATTQQTGDATSLGLASAPWYYHRTVTDSKGKKYTVAETALPQMAVAIAGDENEDGAVNWQDGAIAYRDIMNNPYKSEEVPELVAWRIAMNFGSQAQNPFLTTLDNVKKVALNTDGLGQSVLLKGYGNEGHDSGHPDYGDIGQRLGGADDMNTMMEEGSKYGARFGVHVNASEMYPEAKAFSEDMVRRNSAGGLSYGWNWLDQGVGIDGIYDLASGSRVSRFADLSKEVGDNMDFIYLDVWGNLTSSGSEDSWETRKMSKMINDNGWRMTTEWGSGNEYDSTFQHWAADLTYGGYTSKGENSEVMRFLRNHQKDSWVGDYPQYGGAANAPLLGGYNMKDFEGWQGRNDYAAYIKNLYTHDVSTKFIQHFKVTRWVNNPLLTADNGNAAAVSDPNTNNGNEQITLKDSNGNVVVVSRGSNDTSSAAYRQRTITFNGVKVASGVVSAGDGSATGDESYLLPWMWDSFTGKLVKDSEQKLYHWNTKGGTTTWTLPDSWKNLSSVKVYQLTDQGKTNEQTVAVSGGKVTLTADAETPYVVYKGEAKQIQVNWSEGMHVVDAGFNGGSNTLTDNWTVSGSGKAEVEGDNNAMLRLTGKVDVSQRLTDLKAGQKYALYVGVDNRSTGDASVTVTSGGKVLATNSTGKSIAKNYIKAYGHNTNSNTENGSSYFQNMYVFFTAPENGDATVTLSHKSTDGAHTYFDDVRIVENQYSGITYEKDGTLKSLTNGFENNAQGIWPFVVSGSEGVEDNRIHLSELHAPFTRAGWDVKKMDDVLDGTWSVKVNGLTQKGTLVYQTIPQNVKFEAGAKYKVSFDYQSGSDDIYAIAVGQGEYSAGSVKLTNLKKALGETGKAEFELTGGVNGDSWFGIYSTATAPDLQGSTGNAQDFGGYKDFVLDNLKIERIESQTRTKAEAQDKVKEIRGKYDSKRAELSDAAWQQYQDTLVKARVLINKNGATAEDFTKAYDILVALDEYMKLKDLDRKLLEAARAGQDDEVRILMANGADVNATDIHGHTPLHLAAAMGHLEIVEVLLKNGADVNANDWRGFTPLHLAALNGHLEIVEVLLKNGADVNATDTAGNTPLHLAAWFGHLEIVEVLLKNGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLG 6qep A 2.60 BS02 MN A 2 E727 D752 H1299 E388 D413 H960 31645583 VASETLKTKKMEVQIKKNFPSVLQYTMTDGKVMYGQSKDVRTVEINGTNIELGDDDVTFKKVSDTEATYTLKVKDEAKKIDAVITVQITVKANQLHLNVTKIKNNLSEGIPEGNGVEENAIQTLSFPNQSLVSVRSSQENAQFTGARMSSNTQKPGDTNFAVTEDTNVTDSDYTYGFISGAGLSAGLWSNSEHDGTYVAAPVRGGSQNTRVYATTQQTGDATSLGLASAPWYYHRTVTDSKGKKYTVAETALPQMAVAIAGDENEDGAVNWQDGAIAYRDIMNNPYKSEEVPELVAWRIAMNFGSQAQNPFLTTLDNVKKVALNTDGLGQSVLLKGYGNEGHDSGHPDYGDIGQRLGGADDMNTMMEEGSKYGARFGVHVNASEMYPEAKAFSEDMVRRNSAGGLSYGWNWLDQGVGIDGIYDLASGSRVSRFADLSKEVGDNMDFIYLDVWGNLTSSGSEDSWETRKMSKMINDNGWRMTTEWGSGNEYDSTFQHWAADLTYGGYTSKGENSEVMRFLRNHQKDSWVGDYPQYGGAANAPLLGGYNMKDFEGWQGRNDYAAYIKNLYTHDVSTKFIQHFKVTRWVNNPLLTADNGNAAAVSDPNTNNGNEQITLKDSNGNVVVVSRGSNDTSSAAYRQRTITFNGVKVASGVVSAGDGSATGDESYLLPWMWDSFTGKLVKDSEQKLYHWNTKGGTTTWTLPDSWKNLSSVKVYQLTDQGKTNEQTVAVSGGKVTLTADAETPYVVYKGEAKQIQVNWSEGMHVVDAGFNGGSNTLTDNWTVSGSGKAEVEGDNNAMLRLTGKVDVSQRLTDLKAGQKYALYVGVDNRSTGDASVTVTSGGKVLATNSTGKSIAKNYIKAYGHNTNSNTENGSSYFQNMYVFFTAPENGDATVTLSHKSTDGAHTYFDDVRIVENQYSGITYEKDGTLKSLTNGFENNAQGIWPFVVSGSEGVEDNRIHLSELHAPFTRAGWDVKKMDDVLDGTWSVKVNGLTQKGTLVYQTIPQNVKFEAGAKYKVSFDYQSGSDDIYAIAVGQGEYSAGSVKLTNLKKALGETGKAEFELTGGVNGDSWFGIYSTATAPDLQGSTGNAQDFGGYKDFVLDNLKIERIESQTRTKAEAQDKVKEIRGKYDSKRAELSDAAWQQYQDTLVKARVLINKNGATAEDFTKAYDILVALDEYMKLKDLDRKLLEAARAGQDDEVRILMANGADVNATDIHGHTPLHLAAAMGHLEIVEVLLKNGADVNANDWRGFTPLHLAALNGHLEIVEVLLKNGADVNATDTAGNTPLHLAAWFGHLEIVEVLLKNGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLG 6qep A 2.60 BS03 MN A 3 D601 N603 D605 A607 D612 D262 N264 D266 A268 D273 31645583 VASETLKTKKMEVQIKKNFPSVLQYTMTDGKVMYGQSKDVRTVEINGTNIELGDDDVTFKKVSDTEATYTLKVKDEAKKIDAVITVQITVKANQLHLNVTKIKNNLSEGIPEGNGVEENAIQTLSFPNQSLVSVRSSQENAQFTGARMSSNTQKPGDTNFAVTEDTNVTDSDYTYGFISGAGLSAGLWSNSEHDGTYVAAPVRGGSQNTRVYATTQQTGDATSLGLASAPWYYHRTVTDSKGKKYTVAETALPQMAVAIAGDENEDGAVNWQDGAIAYRDIMNNPYKSEEVPELVAWRIAMNFGSQAQNPFLTTLDNVKKVALNTDGLGQSVLLKGYGNEGHDSGHPDYGDIGQRLGGADDMNTMMEEGSKYGARFGVHVNASEMYPEAKAFSEDMVRRNSAGGLSYGWNWLDQGVGIDGIYDLASGSRVSRFADLSKEVGDNMDFIYLDVWGNLTSSGSEDSWETRKMSKMINDNGWRMTTEWGSGNEYDSTFQHWAADLTYGGYTSKGENSEVMRFLRNHQKDSWVGDYPQYGGAANAPLLGGYNMKDFEGWQGRNDYAAYIKNLYTHDVSTKFIQHFKVTRWVNNPLLTADNGNAAAVSDPNTNNGNEQITLKDSNGNVVVVSRGSNDTSSAAYRQRTITFNGVKVASGVVSAGDGSATGDESYLLPWMWDSFTGKLVKDSEQKLYHWNTKGGTTTWTLPDSWKNLSSVKVYQLTDQGKTNEQTVAVSGGKVTLTADAETPYVVYKGEAKQIQVNWSEGMHVVDAGFNGGSNTLTDNWTVSGSGKAEVEGDNNAMLRLTGKVDVSQRLTDLKAGQKYALYVGVDNRSTGDASVTVTSGGKVLATNSTGKSIAKNYIKAYGHNTNSNTENGSSYFQNMYVFFTAPENGDATVTLSHKSTDGAHTYFDDVRIVENQYSGITYEKDGTLKSLTNGFENNAQGIWPFVVSGSEGVEDNRIHLSELHAPFTRAGWDVKKMDDVLDGTWSVKVNGLTQKGTLVYQTIPQNVKFEAGAKYKVSFDYQSGSDDIYAIAVGQGEYSAGSVKLTNLKKALGETGKAEFELTGGVNGDSWFGIYSTATAPDLQGSTGNAQDFGGYKDFVLDNLKIERIESQTRTKAEAQDKVKEIRGKYDSKRAELSDAAWQQYQDTLVKARVLINKNGATAEDFTKAYDILVALDEYMKLKDLDRKLLEAARAGQDDEVRILMANGADVNATDIHGHTPLHLAAAMGHLEIVEVLLKNGADVNANDWRGFTPLHLAALNGHLEIVEVLLKNGADVNATDTAGNTPLHLAAWFGHLEIVEVLLKNGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLG 6qep A 2.60 BS04 MN A 4 G1108 N1135 A1136 D1248 G769 N796 A797 D909 31645583 VASETLKTKKMEVQIKKNFPSVLQYTMTDGKVMYGQSKDVRTVEINGTNIELGDDDVTFKKVSDTEATYTLKVKDEAKKIDAVITVQITVKANQLHLNVTKIKNNLSEGIPEGNGVEENAIQTLSFPNQSLVSVRSSQENAQFTGARMSSNTQKPGDTNFAVTEDTNVTDSDYTYGFISGAGLSAGLWSNSEHDGTYVAAPVRGGSQNTRVYATTQQTGDATSLGLASAPWYYHRTVTDSKGKKYTVAETALPQMAVAIAGDENEDGAVNWQDGAIAYRDIMNNPYKSEEVPELVAWRIAMNFGSQAQNPFLTTLDNVKKVALNTDGLGQSVLLKGYGNEGHDSGHPDYGDIGQRLGGADDMNTMMEEGSKYGARFGVHVNASEMYPEAKAFSEDMVRRNSAGGLSYGWNWLDQGVGIDGIYDLASGSRVSRFADLSKEVGDNMDFIYLDVWGNLTSSGSEDSWETRKMSKMINDNGWRMTTEWGSGNEYDSTFQHWAADLTYGGYTSKGENSEVMRFLRNHQKDSWVGDYPQYGGAANAPLLGGYNMKDFEGWQGRNDYAAYIKNLYTHDVSTKFIQHFKVTRWVNNPLLTADNGNAAAVSDPNTNNGNEQITLKDSNGNVVVVSRGSNDTSSAAYRQRTITFNGVKVASGVVSAGDGSATGDESYLLPWMWDSFTGKLVKDSEQKLYHWNTKGGTTTWTLPDSWKNLSSVKVYQLTDQGKTNEQTVAVSGGKVTLTADAETPYVVYKGEAKQIQVNWSEGMHVVDAGFNGGSNTLTDNWTVSGSGKAEVEGDNNAMLRLTGKVDVSQRLTDLKAGQKYALYVGVDNRSTGDASVTVTSGGKVLATNSTGKSIAKNYIKAYGHNTNSNTENGSSYFQNMYVFFTAPENGDATVTLSHKSTDGAHTYFDDVRIVENQYSGITYEKDGTLKSLTNGFENNAQGIWPFVVSGSEGVEDNRIHLSELHAPFTRAGWDVKKMDDVLDGTWSVKVNGLTQKGTLVYQTIPQNVKFEAGAKYKVSFDYQSGSDDIYAIAVGQGEYSAGSVKLTNLKKALGETGKAEFELTGGVNGDSWFGIYSTATAPDLQGSTGNAQDFGGYKDFVLDNLKIERIESQTRTKAEAQDKVKEIRGKYDSKRAELSDAAWQQYQDTLVKARVLINKNGATAEDFTKAYDILVALDEYMKLKDLDRKLLEAARAGQDDEVRILMANGADVNATDIHGHTPLHLAAAMGHLEIVEVLLKNGADVNANDWRGFTPLHLAALNGHLEIVEVLLKNGADVNATDTAGNTPLHLAAWFGHLEIVEVLLKNGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLG 6qev B 2.70 BS01 III D 1 Y1557 A1559 L1564 W1567 D1588 S1589 V1590 Y1592 A1600 E1601 Q1623 I1625 L1630 W1633 Y1634 D1654 F1656 K1658 D1666 Y1219 A1221 L1226 W1229 D1250 S1251 V1252 Y1254 A1262 E1263 Q1285 I1287 L1292 W1295 Y1296 D1316 F1318 K1320 D1328 A0A414FD23 31645583 MVACETLKTKKMEVQIKKNFPSVLQYTMTDGKVMYGQSKDVRTVEINGTNIELGDDDVTFKKVSDTEATYTLKVKDEAKKIDAVITVQITVKANQLHLNVTKIKNNLSEGIPEGNGVEENAIQTLSFPNQSLVSVRSSQENAQFTGARMSSNTQKPGDTNFAVTEDTNVTDSDYTYGFISGAGLSAGLWSNSEHDGTYVAAPVRGGSQNTRVYATTQQTGDATSLGLASAPWYYHRTVTDSKGKKYTVAETALPQMAVAIAGDENEDGAVNWQDGAIAYRDIMNNPYKSEEVPELVAWRIAMNFGSQAQNPFLTTLDNVKKVALNTDGLGQSVLLKGYGNEGHDSGHPDYGDIGQRLGGADDMNTMMEEGSKYGARFGVHVNASEMYPEAKAFSEDMVRRNSAGGLSYGWNWLDQGVGIDGIYDLASGSRVSRFADLSKEVGDNMDFIYLDVWGNLTSSGSEDSWETRKMSKMINDNGWRMTTEWGSGNEYDSTFQHWAADLTYGGYTSKGENSEVMRFLRNHQKDSWVGDYPQYGGAANAPLLGGYNMKDFEGWQGRNDYAAYIKNLYTHDVSTKFIQHFKVTRWVNNPLLTADNGNAAAVSDPNTNNGNEQITLKDSNGNVVVVSRGSNDTSSAAYRQRTITFNGVKVASGVVSAGDGSATGDESYLLPWMWDSFTGKLVKDSEQKLYHWNTKGGTTTWTLPDSWKNLSSVKVYQLTDQGKTNEQTVAVSGGKVTLTADAETPYVVYKGEAKQIQVNWSEGMHVVDAGFNGGSNTLTDNWTVSGSGKAEVEGDNNAMLRLTGKVDVSQRLTDLKAGQKYALYVGVDNRSTGDASVTVTSGGKVLATNSTGKSIAKNYIKAYGHNTNSNTENGSSYFQNMYVFFTAPENGDATVTLSHKSTDGAHTYFDDVRIVENQYSGITYEKDGTLKSLTNGFENNAQGIWPFVVSGSEGVEDNRIHLSELHAPFTRAGWDVKKMDDVLDGTWSVKVNGLTQKGTLVYQTIPQNVKFEAGAKYKVSFDYQSGSDDIYAIAVGQGEYSAGSVKLTNLKKALGETGKAEFELTGGVNGDSWFGIYSTATAPDLQGSTGNAQDFGGYKDFVLDNLKIERIESQTRTKAEAQDKVKEIRGKYDSKRAELSDAAWQQYQDTLVKARVLINKNGATAEDFTKAYDILVALDEYMKLKDLDRKLLEAARAGQDDEVRILMANGADVNAKDEYGATPLHLAAWTGHLEIVEVLLKTGADVNAVDSVGYTPLHLAAAEGHLEIVEVLLKTGADVNAQDAQGITPLHLAAWYGHLEIVEVLLKHGADVNAQDCFGKTPFDLAIDNGNEDIAEVLQKAAKLGS 6qev B 2.70 BS02 MN B 1 D601 N603 D605 A607 N609 D612 D263 N265 D267 A269 N271 D274 A0A414FD23 31645583 MVACETLKTKKMEVQIKKNFPSVLQYTMTDGKVMYGQSKDVRTVEINGTNIELGDDDVTFKKVSDTEATYTLKVKDEAKKIDAVITVQITVKANQLHLNVTKIKNNLSEGIPEGNGVEENAIQTLSFPNQSLVSVRSSQENAQFTGARMSSNTQKPGDTNFAVTEDTNVTDSDYTYGFISGAGLSAGLWSNSEHDGTYVAAPVRGGSQNTRVYATTQQTGDATSLGLASAPWYYHRTVTDSKGKKYTVAETALPQMAVAIAGDENEDGAVNWQDGAIAYRDIMNNPYKSEEVPELVAWRIAMNFGSQAQNPFLTTLDNVKKVALNTDGLGQSVLLKGYGNEGHDSGHPDYGDIGQRLGGADDMNTMMEEGSKYGARFGVHVNASEMYPEAKAFSEDMVRRNSAGGLSYGWNWLDQGVGIDGIYDLASGSRVSRFADLSKEVGDNMDFIYLDVWGNLTSSGSEDSWETRKMSKMINDNGWRMTTEWGSGNEYDSTFQHWAADLTYGGYTSKGENSEVMRFLRNHQKDSWVGDYPQYGGAANAPLLGGYNMKDFEGWQGRNDYAAYIKNLYTHDVSTKFIQHFKVTRWVNNPLLTADNGNAAAVSDPNTNNGNEQITLKDSNGNVVVVSRGSNDTSSAAYRQRTITFNGVKVASGVVSAGDGSATGDESYLLPWMWDSFTGKLVKDSEQKLYHWNTKGGTTTWTLPDSWKNLSSVKVYQLTDQGKTNEQTVAVSGGKVTLTADAETPYVVYKGEAKQIQVNWSEGMHVVDAGFNGGSNTLTDNWTVSGSGKAEVEGDNNAMLRLTGKVDVSQRLTDLKAGQKYALYVGVDNRSTGDASVTVTSGGKVLATNSTGKSIAKNYIKAYGHNTNSNTENGSSYFQNMYVFFTAPENGDATVTLSHKSTDGAHTYFDDVRIVENQYSGITYEKDGTLKSLTNGFENNAQGIWPFVVSGSEGVEDNRIHLSELHAPFTRAGWDVKKMDDVLDGTWSVKVNGLTQKGTLVYQTIPQNVKFEAGAKYKVSFDYQSGSDDIYAIAVGQGEYSAGSVKLTNLKKALGETGKAEFELTGGVNGDSWFGIYSTATAPDLQGSTGNAQDFGGYKDFVLDNLKIERIESQTRTKAEAQDKVKEIRGKYDSKRAELSDAAWQQYQDTLVKARVLINKNGATAEDFTKAYDILVALDEYMKLKDLDRKLLEAARAGQDDEVRILMANGADVNAKDEYGATPLHLAAWTGHLEIVEVLLKTGADVNAVDSVGYTPLHLAAAEGHLEIVEVLLKTGADVNAQDAQGITPLHLAAWYGHLEIVEVLLKHGADVNAQDCFGKTPFDLAIDNGNEDIAEVLQKAAKLGS 6qev B 2.70 BS04 MN B 3 G1108 N1110 N1135 A1136 D1248 G770 N772 N797 A798 D910 A0A414FD23 31645583 MVACETLKTKKMEVQIKKNFPSVLQYTMTDGKVMYGQSKDVRTVEINGTNIELGDDDVTFKKVSDTEATYTLKVKDEAKKIDAVITVQITVKANQLHLNVTKIKNNLSEGIPEGNGVEENAIQTLSFPNQSLVSVRSSQENAQFTGARMSSNTQKPGDTNFAVTEDTNVTDSDYTYGFISGAGLSAGLWSNSEHDGTYVAAPVRGGSQNTRVYATTQQTGDATSLGLASAPWYYHRTVTDSKGKKYTVAETALPQMAVAIAGDENEDGAVNWQDGAIAYRDIMNNPYKSEEVPELVAWRIAMNFGSQAQNPFLTTLDNVKKVALNTDGLGQSVLLKGYGNEGHDSGHPDYGDIGQRLGGADDMNTMMEEGSKYGARFGVHVNASEMYPEAKAFSEDMVRRNSAGGLSYGWNWLDQGVGIDGIYDLASGSRVSRFADLSKEVGDNMDFIYLDVWGNLTSSGSEDSWETRKMSKMINDNGWRMTTEWGSGNEYDSTFQHWAADLTYGGYTSKGENSEVMRFLRNHQKDSWVGDYPQYGGAANAPLLGGYNMKDFEGWQGRNDYAAYIKNLYTHDVSTKFIQHFKVTRWVNNPLLTADNGNAAAVSDPNTNNGNEQITLKDSNGNVVVVSRGSNDTSSAAYRQRTITFNGVKVASGVVSAGDGSATGDESYLLPWMWDSFTGKLVKDSEQKLYHWNTKGGTTTWTLPDSWKNLSSVKVYQLTDQGKTNEQTVAVSGGKVTLTADAETPYVVYKGEAKQIQVNWSEGMHVVDAGFNGGSNTLTDNWTVSGSGKAEVEGDNNAMLRLTGKVDVSQRLTDLKAGQKYALYVGVDNRSTGDASVTVTSGGKVLATNSTGKSIAKNYIKAYGHNTNSNTENGSSYFQNMYVFFTAPENGDATVTLSHKSTDGAHTYFDDVRIVENQYSGITYEKDGTLKSLTNGFENNAQGIWPFVVSGSEGVEDNRIHLSELHAPFTRAGWDVKKMDDVLDGTWSVKVNGLTQKGTLVYQTIPQNVKFEAGAKYKVSFDYQSGSDDIYAIAVGQGEYSAGSVKLTNLKKALGETGKAEFELTGGVNGDSWFGIYSTATAPDLQGSTGNAQDFGGYKDFVLDNLKIERIESQTRTKAEAQDKVKEIRGKYDSKRAELSDAAWQQYQDTLVKARVLINKNGATAEDFTKAYDILVALDEYMKLKDLDRKLLEAARAGQDDEVRILMANGADVNAKDEYGATPLHLAAWTGHLEIVEVLLKTGADVNAVDSVGYTPLHLAAAEGHLEIVEVLLKTGADVNAQDAQGITPLHLAAWYGHLEIVEVLLKHGADVNAQDCFGKTPFDLAIDNGNEDIAEVLQKAAKLGS 6qfk A 2.00 BS01 III B 1 T1557 E1559 Y1567 M1590 F1592 H1596 L1597 A1600 W1601 Q1623 V1625 L1630 Y1633 E1634 D1654 F1656 L1663 T1220 E1222 Y1230 M1253 F1255 H1259 L1260 A1263 W1264 Q1286 V1288 L1293 Y1296 E1297 D1317 F1319 L1326 A0A414FD23 31645583 SMVACETLKTKKMEVQIKKNFPSVLQYTMTDGKVMYGQSKDVRTVEINGTNIELGDDDVTFKKVSDTEATYTLKVKDEAKKIDAVITVQITVKANQLHLNVTKIKNNLSEGIPEGNGVEENAIQTLSFPNQSLVSVRSSQENAQFTGARMSSNTQKPGDTNFAVTEDTNVTDSDYTYGFISGAGLSAGLWSNSEHDGTYVAAPVRGGSQNTRVYATTQQTGDATSLGLASAPWYYHRTVTDSKGKKYTVAETALPQMAVAIAGDENEDGAVNWQDGAIAYRDIMNNPYKSEEVPELVAWRIAMNFGSQAQNPFLTTLDNVKKVALNTDGLGQSVLLKGYGNEGHDSGHPDYGDIGQRLGGADDMNTMMEEGSKYGARFGVHVNASEMYPEAKAFSEDMVRRNSAGGLSYGWNWLDQGVGIDGIYDLASGSRVSRFADLSKEVGDNMDFIYLDVWGNLTSSGSEDSWETRKMSKMINDNGWRMTTEWGSGNEYDSTFQHWAADLTYGGYTSKGENSEVMRFLRNHQKDSWVGDYPQYGGAANAPLLGGYNMKDFEGWQGRNDYAAYIKNLYTHDVSTKFIQHFKVTRWVNNPLLTADNGNAAAVSDPNTNNGNEQITLKDSNGNVVVVSRGSNDTSSAAYRQRTITFNGVKVASGVVSAGDGSATGDESYLLPWMWDSFTGKLVKDSEQKLYHWNTKGGTTTWTLPDSWKNLSSVKVYQLTDQGKTNEQTVAVSGGKVTLTADAETPYVVYKGEAKQIQVNWSEGMHVVDAGFNGGSNTLTDNWTVSGSGKAEVEGDNNAMLRLTGKVDVSQRLTDLKAGQKYALYVGVDNRSTGDASVTVTSGGKVLATNSTGKSIAKNYIKAYGHNTNSNTENGSSYFQNMYVFFTAPENGDATVTLSHKSTDGAHTYFDDVRIVENQYSGITYEKDGTLKSLTNGFENNAQGIWPFVVSGSEGVEDNRIHLSELHAPFTRAGWDVKKMDDVLDGTWSVKVNGLTQKGTLVYQTIPQNVKFEAGAKYKVSFDYQSGSDDIYAIAVGQGEYSAGSVKLTNLKKALGETGKAEFELTGGVNGDSWFGIYSTATAPDLQGSTGNAQDFGGYKDFVLDNLKIERIESQTRTKAEAQDKVKEIRGKYDSKRAELSDAAWQQYQDTLVKARVLINKNGATAEDFTKAYDILVALDEYMKLKDLDRKLLEAARAGQDDEVRILMANGADVNADDNTGETPLHLAAYEGHLEIVEVLLKTGADVNAEDMMGFTPLHLAAAWGHLEIVEVLLKHGADVNAQDNQGVTPLHLAAYEGHLEFVEVLLKHGADVNAQDCFGKTPFDLAIDNGNEDIAEVLQKAAKLGS 6qpt A 1.90 BS01 CU A 1 H94 C135 H143 M148 H89 C130 H138 M143 1.7.2.1 U3G913 PGDFGPPRGEPIHAVLTSPPLVPPPVNRTYPAKVIVELEVVEKEMQISEGVSYTFWTFGGTVPGSFIRVRQGDTVEFHLKNHPSSKMPHNIDLHGVTGPGGGAASSFTAPGHESQFTFKALNEGIYVYHCATAPVGMHIANGMYGLILVEPPEGLPKVDHEYYVMQGDFYTAGKYREKGLQPFDMEKAIDERPSYVLFNGAEGALTGDKALHAKVGETVRIFVGNGGPNLVSSFHVIGAIFDQVRYEGGTNVQKNVQTTLIPAGGAAVVKFTARVPGSYVLVDHSIFRAFNKGAMAILKIDGAENKLVYSGKELDSVYLG 6qpt A 1.90 BS02 CU A 2 H99 H134 H94 H129 1.7.2.1 U3G913 PGDFGPPRGEPIHAVLTSPPLVPPPVNRTYPAKVIVELEVVEKEMQISEGVSYTFWTFGGTVPGSFIRVRQGDTVEFHLKNHPSSKMPHNIDLHGVTGPGGGAASSFTAPGHESQFTFKALNEGIYVYHCATAPVGMHIANGMYGLILVEPPEGLPKVDHEYYVMQGDFYTAGKYREKGLQPFDMEKAIDERPSYVLFNGAEGALTGDKALHAKVGETVRIFVGNGGPNLVSSFHVIGAIFDQVRYEGGTNVQKNVQTTLIPAGGAAVVKFTARVPGSYVLVDHSIFRAFNKGAMAILKIDGAENKLVYSGKELDSVYLG 6qpt A 1.90 BS03 NO2 C 1 H240 I242 H289 I291 H235 I237 H284 I286 1.7.2.1 U3G913 PGDFGPPRGEPIHAVLTSPPLVPPPVNRTYPAKVIVELEVVEKEMQISEGVSYTFWTFGGTVPGSFIRVRQGDTVEFHLKNHPSSKMPHNIDLHGVTGPGGGAASSFTAPGHESQFTFKALNEGIYVYHCATAPVGMHIANGMYGLILVEPPEGLPKVDHEYYVMQGDFYTAGKYREKGLQPFDMEKAIDERPSYVLFNGAEGALTGDKALHAKVGETVRIFVGNGGPNLVSSFHVIGAIFDQVRYEGGTNVQKNVQTTLIPAGGAAVVKFTARVPGSYVLVDHSIFRAFNKGAMAILKIDGAENKLVYSGKELDSVYLG 6qpt B 1.90 BS03 NO2 B 1 D97 H99 H134 D92 H94 H129 1.7.2.1 U3G913 PGDFGPPRGEPIHAVLTSPPLVPPPVNRTYPAKVIVELEVVEKEMQISEGVSYTFWTFGGTVPGSFIRVRQGDTVEFHLKNHPSSKMPHNIDLHGVTGPGGGAASSFTAPGHESQFTFKALNEGIYVYHCATAPVGMHIANGMYGLILVEPPEGLPKVDHEYYVMQGDFYTAGKYREKGLQPFDMEKAIDERPSYVLFNGAEGALTGDKALHAKVGETVRIFVGNGGPNLVSSFHVIGAIFDQVRYEGGTNVQKNVQTTLIPAGGAAVVKFTARVPGSYVLVDHSIFRAFNKGAMAILKIDGAENKLVYSGKELDSVYL 6qpt F 1.90 BS01 NO2 E 1 H240 I242 H289 H235 I237 H284 1.7.2.1 U3G913 PGDFGPPRGEPIHAVLTSPPLVPPPVNRTYPAKVIVELEVVEKEMQISEGVSYTFWTFGGTVPGSFIRVRQGDTVEFHLKNHPSSKMPHNIDLHGVTGPGGGAASSFTAPGHESQFTFKALNEGIYVYHCATAPVGMHIANGMYGLILVEPPEGLPKVDHEYYVMQGDFYTAGKYREKGLQPFDMEKAIDERPSYVLFNGAEGALTGDKALHAKVGETVRIFVGNGGPNLVSSFHVIGAIFDQVRYEGGTNVQKNVQTTLIPAGGAAVVKFTARVPGSYVLVDHSIFRAFNKGAMAILKIDGAENKLVYSGKELDSVYLG 6qpv A 1.60 BS03 HEC A 1 T363 C364 V366 C367 H368 P380 P381 L382 S385 F387 I398 V399 L403 N404 G405 I407 Y414 S416 M418 M421 I432 T360 C361 V363 C364 H365 P377 P378 L379 S382 F384 I395 V396 L400 N401 G402 I404 Y411 S413 M415 M418 I429 1.7.2.1 U3G913 KLPGDFGPPRGEPIHAVLTSPPLVPPPVNRTYPAKVIVELEVVEKEMQISEGVSYTFWTFGGTVPGSFIRVRQGDTVEFHLKNHPSSKMPHNIDLHGVTGPGGGAASSFTAPGHESQFTFKALNEGIYVYHCATAPVGMHIANGMYGLILVEPPEGLPKVDHEYYVMQGDFYTAGKYREKGLQPFDMEKAIDERPSYVLFNGAEGALTGDKALHAKVGETVRIFVGNGGPNLVSSFHVIGAIFDQVRYEGGTNVQKNVQTTLIPAGGAAVVKFTARVPGSYVLVDHSIFRAFNKGAMAILKIDGAENKLVYSGKELDSVALGDRAAPNMSAVTKATQASVSGTLTVQDQVQAGRALFAGTCSVCHQGNGAGLPGVFPPLAKSDFLAADPKRAMNIVLHGLNGKIKVNGQEYDSVMPPMTQLNDDEVANILTYVLNSWDNPGGRVSAEDVKKVRAQ 6qpv I 1.60 BS03 HEC I 1 T363 C364 V366 C367 H368 P380 P381 L382 S385 F387 I398 V399 N404 G405 V409 Y414 S416 M418 M421 T359 C360 V362 C363 H364 P376 P377 L378 S381 F383 I394 V395 N400 G401 V405 Y410 S412 M414 M417 1.7.2.1 U3G913 LPGDFGPPRGEPIHAVLTSPPLVPPPVNRTYPAKVIVELEVVEKEMQISEGVSYTFWTFGGTVPGSFIRVRQGDTVEFHLKNHPSSKMPHNIDLHGVTGPGGGAASSFTAPGHESQFTFKALNEGIYVYHCATAPVGMHIANGMYGLILVEPPEGLPKVDHEYYVMQGDFYTAGKYREKGLQPFDMEKAIDERPSYVLFNGAEGALTGDKALHAKVGETVRIFVGNGGPNLVSSFHVIGAIFDQVRYEGGTNVQKNVQTTLIPAGGAAVVKFTARVPGSYVLVDHSIFRAFNKGAMAILKIDGAENKLVYSGKELDSVALGDRAAPNMSAVTKATQASVSGTLTVQDQVQAGRALFAGTCSVCHQGNGAGLPGVFPPLAKSDFLAADPKRAMNIVLHGLNGKIKVNGQEYDSVMPPMTQLNDDEVANILTYVLNSWDNPGGRVSAEDVKKVRAQP 6qpz I 1.65 BS03 HEC I 1 T363 C364 V366 C367 H368 P380 P381 L382 S385 F387 V399 N404 G405 Y414 S416 V417 M418 M421 T359 C360 V362 C363 H364 P376 P377 L378 S381 F383 V395 N400 G401 Y410 S412 V413 M414 M417 1.7.2.1 I6NAW4 LPGDFGPPRGEPIHAVLTSPPLVPPPVNRTYPAKVIVELEVVEKEMQISEGVSYTFWTFGGTVPGSFIRVRQGDTVEFHLKNHPSSKMPHNIDLHGVTGPGGGAASSFTAPGHESQFTFKALNEGIYVYHCATAPVGMHIANGMYGLILVEPPEGLPKVDHEYYVMQGDFYTAGKYREKGLQPFDMEKAIDERPSYVLFNGAEGALTGDKALHAKVGETVRIFVGNGGPNLVSSFHVIGAIFDQVRYEGGTNVQKNVQTTLIPAGGAAVVKFTARVPGSYVLVDHSIFRAFNKGAMAILKIDGAENKLVYSGKELDSVELGDRAAPNMSAVTKATQASVSGTLTVQDQVQAGRALFAGTCSVCHQGNGAGLPGVFPPLAKSDFLAADPKRAMNIVLHGLNGKIKVNGQEYDSVMPPMTQLNDDEVANILTYVLNSWDNPGGRVSAEDVKKVRAQPA 6qqm A 1.75 BS01 ZN A 1 H117 H119 H142 H94 H96 H119 4.2.1.1 G4VLX3 31508507 EWSYTNILTGPETWHEHYKNMCSGYYQSPIDLKTDISTLDLKLKTVIIYRNTSSTETTTIQNNGHSAEVKFPRNTWFISFDGILDYKYEIIQMHFHWGNTDDRGSEHTIDGFRFPLEGHIVSFRRQMYSSPSEAIGRPGGLAVLGIMHQIVESIKYEQTAFKAYNNFSGVLNSQFVPPNNSTIDDINLALLLSLLNPSRYFRYLGSLTTPPCTENVLWTVFIDPVLITREQINLFRNLPYGSNEKQTRMGDNFRPIQLLNPIDTLASRTLYRATARG 6ra7 A 1.20 BS01 MG A 1 S77 H78 H79 I82 T84 S65 H66 H67 I70 T72 2.7.11.1 Q9UKE5 IDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRG 6ra7 A 1.20 BS02 JWK A 1 V31 Y36 A52 K54 M105 E106 F107 C108 G111 L160 D171 V19 Y24 A40 K42 M93 E94 F95 C96 G99 L148 D159 2.7.11.1 Q9UKE5 IDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRG 6rks A 4.00 BS01 NUC E 1 K42 V44 H78 H80 R91 S172 I174 R272 K35 V37 H71 H73 R84 S165 I167 R262 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDARETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN 6rks A 4.00 BS02 NUC G 1 I174 A175 V176 K239 I167 A168 V169 K232 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDARETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN 6rks A 4.00 BS03 JHN G 1 G71 D82 M120 G64 D75 M113 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDARETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN 6rks B 4.00 BS01 NUC G 1 L451 N452 M461 H505 L780 L50 N51 M60 H96 L190 5.99.1.3 GLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rks B 4.00 BS02 NUC H 1 K406 E424 D426 K5 E23 D25 5.99.1.3 GLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rks C 4.00 BS01 NUC F 1 K42 V44 H78 H80 A84 R91 I174 K35 V37 H71 H73 A77 R84 I167 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDARETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN 6rks C 4.00 BS03 JHN G 1 A67 D82 M120 A60 D75 M113 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDARETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN 6rks D 4.00 BS01 NUC F 1 G448 K449 D502 G47 K48 D93 5.99.1.3 GLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rku A 4.00 BS01 NUC E 1 K42 V44 H45 H78 H80 A84 I174 R272 K35 V37 H38 H71 H73 A77 I167 R265 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN 6rku A 4.00 BS02 NUC G 1 I174 A175 V176 A179 R237 K239 S329 I167 A168 V169 A172 R230 K232 S322 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN 6rku A 4.00 BS03 JHN G 1 D82 M120 D75 M113 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN 6rku B 4.00 BS01 NUC G 1 L451 N452 K455 M461 H505 L780 L50 N51 K54 M60 H96 L371 5.6.2.3 P0AES6 GLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rku B 4.00 BS02 NUC H 1 K406 E424 D426 K5 E23 D25 5.6.2.3 P0AES6 GLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rku C 4.00 BS01 NUC F 1 R32 K42 V44 H80 A84 R91 I174 R272 R25 K35 V37 H73 A77 R84 I167 R265 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN 6rku C 4.00 BS02 NUC H 1 I174 V176 K239 I167 V169 K232 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN 6rku D 4.00 BS01 NUC F 1 K449 D502 K48 D93 5.6.2.3 P0AES6 GLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rku D 4.00 BS03 NUC H 1 L451 N452 K455 M461 L780 L50 N51 K54 M60 L371 5.6.2.3 P0AES6 GLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rkv A 4.60 BS01 NUC E 1 R32 K42 V44 H45 H78 H80 T88 S172 R272 R25 K35 V37 H38 H71 H73 T81 S165 R265 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN 6rkv A 4.60 BS02 NUC G 1 I174 A175 V176 R237 K239 S329 I167 A168 V169 R230 K232 S322 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN 6rkv B 4.60 BS01 NUC G 1 K449 L451 N452 K455 M461 F777 L780 D783 K48 L50 N51 K54 M60 F368 L371 D374 5.6.2.3 P0AES6 GLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rkv C 4.60 BS01 NUC F 1 R32 V44 H80 R91 I174 R25 V37 H73 R84 I167 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN 6rkv C 4.60 BS02 NUC H 1 Y21 I174 V176 R237 K239 S329 Y14 I167 V169 R230 K232 S322 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITAN 6rkv D 4.60 BS01 NUC F 1 G448 K449 F458 D502 G47 K48 F57 D93 5.6.2.3 P0AES6 GLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rkv D 4.60 BS02 NUC H 1 L451 N452 K455 M461 D783 L50 N51 K54 M60 D374 5.6.2.3 P0AES6 GLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rkw A 6.60 BS01 NUC E 1 V44 H80 A84 T88 R91 I174 Q267 R272 K567 S568 E700 K702 R712 M714 G720 V721 K769 G770 V771 I772 V37 H73 A77 T81 R84 I167 Q260 R265 K554 S555 E687 K689 R699 M701 G707 V708 K756 G757 V758 I759 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAE 6rkw A 6.60 BS02 NUC G 1 I174 A175 V176 K239 G564 R722 R725 R766 A767 K775 T777 R779 N780 N818 T819 Q820 I167 A168 V169 K232 G551 R709 R712 R753 A754 K762 T764 R766 N767 N805 T806 Q807 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAE 6rkw C 6.60 BS01 NUC F 1 V44 H78 H80 A84 D87 T88 I174 R272 K567 T654 K702 R712 M714 T719 G720 V721 R722 K769 I772 V776 V37 H71 H73 A77 D80 T81 I167 R265 K554 T641 K689 R699 M701 T706 G707 V708 R709 K756 I759 V763 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAE 6rkw C 6.60 BS02 NUC H 1 I174 A175 V176 K239 G563 K671 N717 R722 I724 R725 L726 G727 E728 A767 K775 R779 E811 N818 T819 Q820 G821 I167 A168 V169 K232 G550 K658 N704 R709 I711 R712 L713 G714 E715 A754 K762 R766 E798 N805 T806 Q807 G808 5.6.2.3 P0AES4 ITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAAGDDAARPEWLEPEFGVGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAE 6rkw B 6.60 BS02 NUC G 1 L451 N452 K455 L780 L450 N451 K454 L771 5.6.2.3 P0AES6 SNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rkw B 6.60 BS03 NUC H 1 E424 D426 K447 E423 D425 K446 5.6.2.3 P0AES6 SNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rkw B 6.60 BS04 ANP B 1 E42 N46 I78 I94 A100 G101 G102 K103 Y109 G114 L115 H116 G117 V118 G119 V120 Q335 E41 N45 I77 I93 A99 G100 G101 K102 Y108 G113 L114 H115 G116 V117 G118 V119 Q334 5.6.2.3 P0AES6 SNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rkw D 6.60 BS02 NUC G 1 K307 K406 E424 D426 K447 K306 K405 E423 D425 K446 5.6.2.3 P0AES6 SNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rkw D 6.60 BS04 ANP D 1 E42 N46 A47 E50 D73 I78 I94 G102 K103 Y109 G114 L115 H116 G117 V118 G119 V120 E41 N45 A46 E49 D72 I77 I93 G101 K102 Y108 G113 L114 H115 G116 V117 G118 V119 5.6.2.3 P0AES6 SNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGETEKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRA 6rwf A 1.64 BS02 CO A 2 Q175 E212 E217 W367 Q174 E211 E216 W366 3.2.1.- G0RVK1 SACTLQSETHPPLTWQKCSSGGTCTQQTGSVVIDANWRWTHATNSSTNCYDGNTWSSTLCPDNETCAKNCCLDGAAYASTYGVTTSGNSLSIGFVTQSAQKNVGARLYLMASDTTYQEFTLLGNEFSFDVDVSQLPCGLNGALYFVSMDADGGVSKYPTNTAGAKYGTGYCDSQCPRDLKFINGQANVEGWEPSSNNANTGIGGHGSCCSEMDIWEANSISEALTPHPCTTVGQEICEGDGCGGCYSDNRYGGTCDPDGCDWNPYRLGNTSFYGPGSSFTLDTTKKLTVVTQFETSGAINRYYVQNGVTFQQPNAELGSYSGNELNDDYCTAEEAEFGGSSFSDKGGLTQFKKATSGGMVLVMSLWDDYCANMLWLDSTYPTNETSSTPGAVRGSCSTSSGVPAQVESQSPNAKVTFSNIKFGPIGSTGNP 6s00 A 2.00 BS01 SLB A 1 D14 N15 S16 C53 W95 R129 H134 R202 W279 F345 N346 Q351 T352 D9 N10 S11 C48 W90 R124 H129 R197 W274 F340 N341 Q346 T347 3.2.1.18 31645552 IPGISLNEDNSHYFYTRAGRRLSAEEVDSWVDQYAGTQVKELMLCPNCMRTSYASQVWDPIWRGYDPAGPDDQPLLASLPPEERVAARGWIHTAWQLHQDGIDIYARWIRRCRQRGISPWISMRMNDVHYVNDERCFLHSEFWRENPQLRRVPYRFAEWTDRAFDYGRAEVREHHLKLIRELAARYDFDGLELDWMRFGFHFRPGYEAEGAEILTAFTAEVRRLLDDWEKRRGHKIHLGARIPSRPATALGLGMDAVTWARRGLVDMLVITPFWASAETDMPVEIWRQLLEGTGVTLAAGLEVLLRPYPDSPLFQTNSLETVRGAAASLLDRGAQRIYLFNYMDSQTAMEDLENYPTLLREIGSLETLAGKPRRHVLTFADTWAPGEPRAIPLPATCRPGEWRAFRLHTGPKPEPGEVIAALGIEGAIGPETLEVRVNGELCAFLGLVDLSKPRPDFPVYGFSVPLAAMRRGYNLIEVTARQELRFGWAEFLIRP 6s0e B 1.90 BS01 DAN B 1 D14 N15 S16 Y20 W95 R129 H134 R202 W279 N346 Q351 T352 D9 N10 S11 Y15 W90 R124 H129 R197 W274 N341 Q346 T347 3.2.1.18 31645552 IPGISLNEDNSHYFYTRAGRRLSAEEVDSWVDQYAGTQVKELMLCPNCMRTSYASQVWDPIWRGYDPAGPDDQPLLASLPPEERVAARGWIHTAWQLHQDGIDIYARWIRRCRQRGISPWISMRMNDVHYVNDERCFLHSEFWRENPQLRRVPYRFAEWTDRAFDYGRAEVREHHLKLIRELAARYDFDGLELDWMRFGFHFRPGYEAEGAEILTAFTAEVRRLLDDWEKRRGHKIHLGARIPSRPATALGLGMDAVTWARRGLVDMLVITPFWASAETDMPVEIWRQLLEGTGVTLAAGLEVLLRPYPDSPLFQTNSLETVRGAAASLLDRGAQRIYLFNYMDSQTAMEDLENYPTLLREIGSLETLAGKPRRHVLTFADTWAPGEPRAIPLPATCRPGEWRAFRLHTGPKPEPGEVIAALGIEGGAIGPETLEVRVNGELCAFLGLVDLSKPRPDFPVYGFSVPLAAMRRGYNLIEVTARQELRFGWAEFLIRP 6s0f A 2.00 BS01 KDN A 1 D14 N15 S16 C53 W95 R129 H134 R202 W279 N346 T352 D9 N10 S11 C48 W90 R124 H129 R197 W274 N341 T347 3.2.1.18 31645552 IPGISLNEDNSHYFYTRAGRRLSAEEVDSWVDQYAGTQVKELMLCPNCMRTSYASQVWDPIWRGYDPAGPDDQPLLASLPPEERVAARGWIHTAWQLHQDGIDIYARWIRRCRQRGISPWISMRMNDVHYVNDERCFLHSEFWRENPQLRRVPYRFAEWTDRAFDYGRAEVREHHLKLIRELAARYDFDGLELDWMRFGFHFRPGYEAEGAEILTAFTAEVRRLLDDWEKRRGHKIHLGARIPSRPATALGLGMDAVTWARRGLVDMLVITPFWASAETDMPVEIWRQLLEGTGVTLAAGLEVLLRPYPDSPLFQTNSLETVRGAAASLLDRGAQRIYLFNYMDSQTAMEDLENYPTLLREIGSLETLAGKPRRHVLTFADTWAPGEPRAIPLPATCRPGEWRAFRLHTGPKPEPGEVIAALGIEGGVAIGPETLEVRVNGELCAFLGLVDLSKPRPDFPVYGFSVPLAAMRRGYNLIEVTARQELRFGWAEFLIRP 6sh9 B 2.40 BS01 III E 1 F1559 L1564 W1567 R1590 H1592 L1597 Y1600 D1621 T1625 L1630 M1633 F1222 L1227 W1230 R1253 H1255 L1260 Y1263 D1284 T1288 L1293 M1296 3.2.1.97 Q3T552 31645583 SMVACETLKTKKMEVQIKKNFPSVLQYTMTDGKVMYGQSKDVRTVEINGTNIELGDDDVTFKKVSDTEATYTLKVKDEAKKIDAVITVQITVKANQLHLNVTKIKNNLSEGIPEGNGVEENAIQTLSFPNQSLVSVRSSQENAQFTGARMSSNTQKPGDTNFAVTEDTNVTDSDYTYGFISGAGLSAGLWSNSEHDGTYVAAPVRGGSQNTRVYATTQQTGDATSLGLASAPWYYHRTVTDSKGKKYTVAETALPQMAVAIAGDENEDGAVNWQDGAIAYRDIMNNPYKSEEVPELVAWRIAMNFGSQAQNPFLTTLDNVKKVALNTDGLGQSVLLKGYGNEGHDSGHPDYGDIGQRLGGADDMNTMMEEGSKYGARFGVHVNASEMYPEAKAFSEDMVRRNSAGGLSYGWNWLDQGVGIDGIYDLASGSRVSRFADLSKEVGDNMDFIYLDVWGNLTSSGSEDSWETRKMSKMINDNGWRMTTEWGSGNEYDSTFQHWAADLTYGGYTSKGENSEVMRFLRNHQKDSWVGDYPQYGGAANAPLLGGYNMKDFEGWQGRNDYAAYIKNLYTHDVSTKFIQHFKVTRWVNNPLLTADNGNAAAVSDPNTNNGNEQITLKDSNGNVVVVSRGSNDTSSAAYRQRTITFNGVKVASGVVSAGDGSATGDESYLLPWMWDSFTGKLVKDSEQKLYHWNTKGGTTTWTLPDSWKNLSSVKVYQLTDQGKTNEQTVAVSGGKVTLTADAETPYVVYKGEAKQIQVNWSEGMHVVDAGFNGGSNTLTDNWTVSGSGKAEVEGDNNAMLRLTGKVDVSQRLTDLKAGQKYALYVGVDNRSTGDASVTVTSGGKVLATNSTGKSIAKNYIKAYGHNTNSNTENGSSYFQNMYVFFTAPENGDATVTLSHKSTDGAHTYFDDVRIVENQYSGITYEKDGTLKSLTNGFENNAQGIWPFVVSGSEGVEDNRIHLSELHAPFTRAGWDVKKMDDVLDGTWSVKVNGLTQKGTLVYQTIPQNVKFEAGAKYKVSFDYQSGSDDIYAIAVGQGEYSAGSVKLTNLKKALGETGKAEFELTGGVNGDSWFGIYSTATAPDLQGSTGNAQDFGGYKDFVLDNLKIERIESQTRTKAEAQDKVKEIRGKYDSKRAELSDAAWQQYQDTLVKARVLINKNGATAEDFTKAYDILVALDEYMKLKDLDRKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHLEIVEVLLKNGADVNIQDCFGKTAFDISIDNGNEDLAEIL 6snc A 3.20 BS01 III C 1 H92 S93 T94 H92 S93 T94 31653484 DIQMTQSPSSLSASVGDKVTITCRASQSVTKYLNWYQFKTGQAPRILIYGTYTLLSGVSPRFSGAGSGSLYTLTITNIQPEDFATYYCQQAHSTPWTFGQGTHVAANRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGG 6snc B 3.20 BS01 III C 1 Y35 T50 Y58 F100 S100B F100E S100F W100H Y34 T51 Y59 F104 S106 F109 S110 W112 31653484 VQLVESGPGLVQPWGTLSLTCRVSGDSVSNDNYYWAWIRQTPGRELQVIGTIYYSGTTYYNPSLRNRVTISLDKSVNVVSLRLGSVSAADTAQYYCVRMPSHGFWSTSFSYWYFDLWGRGHFVAVSWASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVDHKPSNTKVDKKVEPKSC 6snc L 3.20 BS01 III P 1 Y32 H92 S93 T94 W96 Y32 H92 S93 T94 W96 31653484 DIQMTQSPSSLSASVGDKVTITCRASQSVTKYLNWYQFKTGQAPRILIYGTYTLLSGVSPRFSGAGSGSLYTLTITNIQPEDFATYYCQQAHSTPWTFGQGTHVAANRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFN 6snc L 3.20 BS02 PC P 1 T30 K31 Y32 T30 K31 Y32 31653484 DIQMTQSPSSLSASVGDKVTITCRASQSVTKYLNWYQFKTGQAPRILIYGTYTLLSGVSPRFSGAGSGSLYTLTITNIQPEDFATYYCQQAHSTPWTFGQGTHVAANRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFN 6snc H 3.20 BS01 III P 1 Y35 T50 Y58 F100 W100A S100B F100E S100F W100H Y34 T51 Y59 F104 W105 S106 F109 S110 W112 31653484 VQLVESGPGLVQPWGTLSLTCRVSGDSVSNDNYYWAWIRQTPGRELQVIGTIYYSGTTYYNPSLRNRVTISLDKSVNVVSLRLGSVSAADTAQYYCVRMPSHGFWSTSFSYWYFDLWGRGHFVAVSWASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVDHKPSNTKVDKKVEPKS 6snc H 3.20 BS02 DPV H 1 D32 N33 Y52 S97 G99 F100 W100A D31 N32 Y53 S101 G103 F104 W105 31653484 VQLVESGPGLVQPWGTLSLTCRVSGDSVSNDNYYWAWIRQTPGRELQVIGTIYYSGTTYYNPSLRNRVTISLDKSVNVVSLRLGSVSAADTAQYYCVRMPSHGFWSTSFSYWYFDLWGRGHFVAVSWASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVDHKPSNTKVDKKVEPKS 6snd A 3.10 BS01 III C 1 H92 S93 T94 W96 H92 S93 T94 W96 31653484 DIQMTQSPSSLSASVGDKVTITCRASQSVTKYLNWYQFKTGQAPRILIYGTYTLLSGVSPRFSGAGSGSLYTLTITNIQPEDFATYYCQQAHSTPWTFGQGTHVAANRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGG 6snd A 3.10 BS02 DPV A 1 T30 Y32 T30 Y32 31653484 DIQMTQSPSSLSASVGDKVTITCRASQSVTKYLNWYQFKTGQAPRILIYGTYTLLSGVSPRFSGAGSGSLYTLTITNIQPEDFATYYCQQAHSTPWTFGQGTHVAANRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGG 6snd B 3.10 BS01 III C 1 Y35 T50 M95 F100 W100A S100B F100E S100F W100H Y34 T51 M99 F104 W105 S106 F109 S110 W112 31653484 VQLVESGPGLVQPWGTLSLTCRVSGDSVSNDNYYWAWIRQTPGRELQVIGTIYYSGTTYYNPSLRNRVTISLDKSVNVVSLRLGSVSAADTAQYYCVRMPSHGFWSTSFSYWYFDLWGRGHFVAVSWASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVDHKPSNTKVDKKVEPKSC 6snd H 3.10 BS02 PSF H 1 D32 Y52 S97 G99 F100 W100A D32 Y54 S102 G104 F105 W106 31653484 EVQLVESGPGLVQPWGTLSLTCRVSGDSVSNDNYYWAWIRQTPGRELQVIGTIYYSGTTYYNPSLRNRVTISLDKSVNVVSLRLGSVSAADTAQYYCVRMPSHGFWSTSFSYWYFDLWGRGHFVAVSWASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVDHKPSNTKVDKKVEPKS 6sne B 3.90 BS01 PC B 1 T100C S100D Y100G T107 S108 Y111 31653484 VQLVESGPGLVQPWGTLSLTCRVSGDSVSNDNYYWAWIRQTPGRELQVIGTIYYSGTTYYNPSLRNRVTISLDKSVNVVSLRLGSVSAADTAQYYCVRMPSHGFWSTSFSYWYFDLWGRGHFVAVSWASTKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVDHKPSNTKVDKKVEPKS 6sne F 3.90 BS01 PC F 1 D32 N33 G99 D31 N32 G103 31653484 VQLVESGPGLVQPWGTLSLTCRVSGDSVSNDNYYWAWIRQTPGRELQVIGTIYYSGTTYYNPSLRNRVTISLDKSVNVVSLRLGSVSAADTAQYYCVRMPSHGFWSTSFSYWYFDLWGRGHFVAVSWASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVDHKPSNTKVDKKVEPKS 6sne H 3.90 BS01 PC H 1 T100C Y100G T107 Y111 31653484 VQLVESGPGLVQPWGTLSLTCRVSGDSVSNDNYYWAWIRQTPGRELQVIGTIYYSGTTYYNPSLRNRVTISLDKSVNVVSLRLGSVSAADTAQYYCVRMPSHGFWSTSFSYWYFDLWGRGHFVAVSWASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVDHKPSNTKVDKKVEPKS 6sne H 3.90 BS02 PC P 1 Y52 F100 Y53 F104 31653484 VQLVESGPGLVQPWGTLSLTCRVSGDSVSNDNYYWAWIRQTPGRELQVIGTIYYSGTTYYNPSLRNRVTISLDKSVNVVSLRLGSVSAADTAQYYCVRMPSHGFWSTSFSYWYFDLWGRGHFVAVSWASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVDHKPSNTKVDKKVEPKS 6sne D 3.90 BS01 PC D 1 S100D Y100G S108 Y111 31653484 VQLVESGPGLVQPWGTLSLTCRVSGDSVSNDNYYWAWIRQTPGRELQVIGTIYYSGTTYYNPSLRNRVTISLDKSVNVVSLRLGSVSAADTAQYYCVRMPSHGFWSTSFSYWYFDLWGRGHFVAVSWASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVDHKPSNTKVDKKVEPKS 6sne D 3.90 BS02 PC D 2 G99 F100 G103 F104 31653484 VQLVESGPGLVQPWGTLSLTCRVSGDSVSNDNYYWAWIRQTPGRELQVIGTIYYSGTTYYNPSLRNRVTISLDKSVNVVSLRLGSVSAADTAQYYCVRMPSHGFWSTSFSYWYFDLWGRGHFVAVSWASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVDHKPSNTKVDKKVEPKS 6sne J 3.90 BS01 PC C 1 W680 Y681 W13 Y14 Q74599 31653484 SLWNWFNITNWLWYIKLFIMIVGGLVGLRIVFAV 6so9 A BS01 NUC B 1 H523 C525 N526 E529 I551 L552 M553 K554 S555 Q558 F560 L589 R591 S593 T594 R595 Y596 E598 L599 Q600 L601 K602 K603 H14 C16 N17 E20 I42 L43 M44 K45 S46 Q49 F51 L80 R82 S84 T85 R86 Y87 E89 L90 Q91 L92 K93 K94 Q3UQS8 GAMAQRKGAGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEKPAIINGEKLLIRMSTRYKELQLKKPGKNVAAIIQDIHSQRER 6soz C 3.42 BS01 FE C 1 D392 Y426 R456 T457 Y517 H585 D382 Y416 R446 T447 Y507 H575 P02787 31636418 DKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANFFSGSCAPCADGTDFPQLCQLCPGCGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDAKMYLGYEYVTAIRNLREGTCPPVKWCALSHHERLKCDEWSVNSVGKIECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGKCGLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSASDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYNKINHCRFDEFFSEGCAPGSKKDSSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKDKEACVHKILRQQQHLFKDLLFRDDTVCLAKLHDRNTYEKYLGEEYVKAVGNLRKCSTSSLLEACTFRRP 6sqg A 1.90 BS01 RET A 1 W76 T80 M83 M116 G120 G133 G137 W169 Y172 G173 Y176 D191 K195 W75 T79 M82 M115 G119 G132 G136 W168 Y171 G172 Y175 D190 K194 F2Y2Z0 SDLIEYSFYLTYAFLMTTGTITFIEALRTKNESVRHILNLETCISVVAAFFYSNFIGKLEHINYEEINLNRYVDWAITTPIMLLVLVLAFRVNQTNKAMVKFSDFMIILGMNYGMLGTGYLGDIGVIHKTMGTVLGFLFFGGLFYKLNTLRTSNASNDLLYGAFFVLWALYGVFYQMEQLPRNVGYNVLDLFSKCFVGIYFWAFYAKIFT 6sqg B 1.90 BS01 RET B 1 W76 M83 M116 G133 G137 W169 Y172 G173 Y176 D191 K195 W75 M82 M115 G132 G136 W168 Y171 G172 Y175 D190 K194 F2Y2Z0 SDLIEYSFYLTYAFLMTTGTITFIEALRTKNESVRHILNLETCISVVAAFFYSNFIGKLEHINYEEINLNRYVDWAITTPIMLLVLVLAFRVNQTNKAMVKFSDFMIILGMNYGMLGTGYLGDIGVIHKTMGTVLGFLFFGGLFYKLNTLRTSNASNDLLYGAFFVLWALYGVFYQMEQLPRNVGYNVLDLFSKCFVGIYFWAFYAKIFT 6t1i A 1.80 BS01 M7W A 1 F28 H56 S58 F59 P60 S76 G77 Y78 A79 G80 F27 H55 S57 F58 P59 S75 G76 Y77 A78 G79 Q03111 DNQCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVM 6tzm A 1.71 BS01 GDP A 1 G422 C423 G424 K425 T426 T427 R528 D583 K588 S589 S590 G15 C16 G17 K18 T19 T20 R121 D165 K170 S171 S172 6.5.1.3 P43075 STTTKYIFVPIATIGCGKTTVFNTLNNLFPQWTHIQNDNISKKAKLKICDLTLLALEDDDQSVVLFDRNNSASRERRQIFTTIDQKRDEHLDDTVDLKYIAINFIPEDLSEEELWDITYNRVIQLDENLVESVMKGFIQRYQPINTSRSPDDQFDHVIHLKLSKDENSLKSSLENVRIIIDDLVQNFPDLIKEKPADELINECFQKALDYK 6tzo A 1.69 BS01 DGI A 1 G422 C423 G424 K425 T426 T427 R528 R532 G533 D534 D583 K588 S589 S590 G16 C17 G18 K19 T20 T21 R122 R126 G127 D128 D177 K182 S183 S184 6.5.1.3 P43075 LSTTTKYIFVPIATIGCGKTTVFNTLNNLFPQWTHIQNNNISKKAKLKICDLTLLALEDDDQSVVLFDRNNSASRERRQIFTTIDQKRDEHLDDTVDLKYIAINFIPEDLSEEELWDITYNRVIQRGDNHQSIKSQLDENLVESVMKGFIQRYQPINTSRSPDDQFDHVIHLKLSKDENSLKSSLENVRIIIDDLVQNFPDLIKEKPADELINECFQKALDYKP 6tzo A 1.69 BS02 PO4 A 1 N444 N445 D474 R475 N476 H536 N38 N39 D68 R69 N70 H130 6.5.1.3 P43075 LSTTTKYIFVPIATIGCGKTTVFNTLNNLFPQWTHIQNNNISKKAKLKICDLTLLALEDDDQSVVLFDRNNSASRERRQIFTTIDQKRDEHLDDTVDLKYIAINFIPEDLSEEELWDITYNRVIQRGDNHQSIKSQLDENLVESVMKGFIQRYQPINTSRSPDDQFDHVIHLKLSKDENSLKSSLENVRIIIDDLVQNFPDLIKEKPADELINECFQKALDYKP 6tzx A 1.53 BS02 PO4 A 1 K425 N445 N476 H536 K18 N38 N69 H129 6.5.1.3 P43075 STTTKYIFVPIATIGCGKTTVFNTLNNLFPQWTHIQNNNISKKAKLKICDLTLLALEDDDQSVVLFDRNNSASRERRQIFTTIDQKRDEHLDDTVDLKYIAINFIPEDLSEEELWDITYNRVIQRGDNHQSIKSQLDENLVESVMKGFIQRYQPINTSRSPDDQFDHVIHLKLSKDENSLKSSLENVRIIIDDLVQNFPDLIKEKPADELINECFQKALDYKP 6u00 A 1.98 BS01 PO4 A 1 T420 I421 G422 K425 T426 T12 I13 G14 K17 T18 6.5.1.3 P43075 TTTKYIFVPIATIGCGKTTVFNTLNNLFPQWTHIQNDNISKKAKLKICDLTLLALEDDDQSVVLFDRNNSASRERRQIFTTIDQKRDEHLDDTVDLKYIAINFIPEDLSEEELWDITYNRVIQLDENLVESVMKGFIQRYQPINTSRSPDDQFDHVIHLKLSKDENSLKSSLENVRIIIDDLVQNFPDLIKEKPADELINECFQKALDYKP 6u00 B 1.98 BS01 PO4 B 1 I421 G422 C423 G424 T426 I13 G14 C15 G16 T18 6.5.1.3 P43075 TTTKYIFVPIATIGCGKTTVFNTLNNLFPQWTHIQNDNISKKAKLKICDLTLLALEDDDQSVVLFDRNNSASRERRQIFTTIDQKRDEHLDDTVDLKYIAINFIPEDLSEEELWDITYNRVILDENLVESVMKGFIQRYQPINTSRSPDDQFDHVIHLKLSKDENSLKSSLENVRIIIDDLVQNFPDLIKEKPADELINECFQKALDYKP 6u03 A 1.85 BS01 GTP A 1 I421 G422 C423 G424 K425 T426 T427 N445 R528 R532 D583 K588 S589 S590 I15 G16 C17 G18 K19 T20 T21 N39 R122 R126 D169 K174 S175 S176 6.5.1.3 P43075 LSTTTKYIFVPIATIGCGKTTVFNTLNNLFPQWTHIQNNNISKKAKLKICDLTLLALEDDDQSVVLFDRNNSASRERRQIFTTIDQKRDEHLDDTVDLKYIAINFIPEDLSEEELWDITYNRVIQRSQLDENLVESVMKGFIQRYQPINTSRSPDDQFDHVIHLKLSKDENSLKSSLENVRIIIDDLVQNFPDLIKEKPADELINECFQKALDYKP 6u05 A 1.95 BS02 MG A 1 T426 D445 T18 D37 6.5.1.3 P43075 TTTKYIFVPIATIGCGKTTVFNTLNNLFPQWTHIQNDNISKKAKLKICDLTLLALEDDDQSVVLFDRNNSASRERRQIFTTIDQKRDEHLDDTVDLKYIAINFIPEDLSEEELWDITYNRVIQLDENLVESVMKGFIQRYQPINTSRSPDDQFDHVIHLKLSKDENSLKSSLENVRIIIDDLVQNFPDLIKEKPADELINECFQKALDYKPTFVKNMTANTIKKDPTYYGIAMHYSSILENLEIVSHNEHFQNIKSHIQTEFHVTLGHIASSKQDKAGRVKWKKLVKTLGKGDPNKPKSALKFFADVKLLQIVINTDKLACIKVEILKIYDTNDVLQSEIEPINKQLHITIGCIPPATAVESNITLEELYDNPDEQELKPDGTYKCGDDTLHVFNFDNPDLKLFSQQLFVAYQ 6u05 A 1.95 BS03 PO4 A 1 H682 T684 H767 T769 A778 V779 H263 T265 H348 T350 A359 V360 6.5.1.3 P43075 TTTKYIFVPIATIGCGKTTVFNTLNNLFPQWTHIQNDNISKKAKLKICDLTLLALEDDDQSVVLFDRNNSASRERRQIFTTIDQKRDEHLDDTVDLKYIAINFIPEDLSEEELWDITYNRVIQLDENLVESVMKGFIQRYQPINTSRSPDDQFDHVIHLKLSKDENSLKSSLENVRIIIDDLVQNFPDLIKEKPADELINECFQKALDYKPTFVKNMTANTIKKDPTYYGIAMHYSSILENLEIVSHNEHFQNIKSHIQTEFHVTLGHIASSKQDKAGRVKWKKLVKTLGKGDPNKPKSALKFFADVKLLQIVINTDKLACIKVEILKIYDTNDVLQSEIEPINKQLHITIGCIPPATAVESNITLEELYDNPDEQELKPDGTYKCGDDTLHVFNFDNPDLKLFSQQLFVAYQ 6u25 A 2.61 BS01 O5B A 1 Q286 L287 C320 H323 L324 A327 V361 R364 M365 R367 A368 F378 F388 L391 L396 I397 I400 F401 H479 Q23 L24 C57 H60 L61 A64 V98 R101 M102 R104 A105 F115 F125 L128 L133 I134 I137 F138 H216 2.3.1.48 Q15788 31638797 MASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFSKILHRLLQE 6u26 B 1.53 BS01 063 B 1 Y293 C323 A328 S329 A330 P331 V333 T335 R357 C358 D360 R412 R458 V460 W461 A463 I474 A475 R476 C477 A478 K506 Y124 C154 A159 S160 A161 P162 V164 T166 R188 C189 D191 R243 R289 V291 W292 A294 I305 A306 R307 C308 A309 K337 3.4.21.- Q8NBP7 31653597 SIPWNLERITPPRYRSLVEVYLLDTSIQSDHREIEGRVMVTDFENVPEEDASKCDSHGTHLAGVVSGRDAGVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVLNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHGAGWQLFCRTVWSAHSGPTRMATAIARCAPDEELLSCSSFSRSGKRRGERMEAQGGKLVCRAHNAFGGEGVYAIARCCLLPQANCSVHTAPPATRVHCHQQGHVLTGCSSHWEVEDQPNQCVGHREASIHASCCHAPGLECKVKEHGIPEQVTVACEEGWTLTGCSALPSHVLGAYAVDNTCVVRSRAVTAVAICCRSR 6u2n B 2.15 BS01 PV7 B 1 A328 S329 A330 P331 V333 T335 R357 C358 D360 R458 V460 W461 R476 C477 A478 A159 S160 A161 P162 V164 T166 R188 C189 D191 R287 V289 W290 R304 C305 A306 3.4.21.- Q8NBP7 31653597 SIPWNLERITPPRYRASLVEVYLLDTSIQSDHREIEGRVMVTDFENVPEEDSKCDSHGTHLAGVVSGRDAGVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVLNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHGWQLFCRTVWSAHSGPTMATAIARCAPDEELLSCSSFSRSGKRRGERMEAQGGKLVCRAHNAFGGEGVYAIARCCLLPQANCSVHTAPPAMGTRVHCHQQGHVLTGCSSHWEVEDQPNQCVGHREASIHASCCHAPGLECKVKEHGIPQEQVTVACEEGWTLTGCSALPSHVLGAYAVDNTCVVRSRAVTAVAICCRSR 6u2p B 2.04 BS01 PUV B 1 A328 S329 A330 P331 V333 T335 R357 C358 D360 R412 R458 V460 W461 A475 R476 C477 A478 A158 S159 A160 P161 V163 T165 R187 C188 D190 R242 R286 V288 W289 A303 R304 C305 A306 3.4.21.- Q8NBP7 31653597 SIPWNLERITPPRYRLVEVYLLDTSIQSDHREIEGRVMVTDFENVPEEDASKCDSHGTHLAGVVSGRDAGVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVLNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHGWQLFCRTVWSAHSGPTRMATAIARCAPDEELLSCSSFSRSGKRRGERMEAQGGKLVCRAHNAFGGEGVYAIARCCLLPANCSVHTAPPAASMGTRVHCHQQGHVLTGCSSHWEVEDLQPNQCVGHREASIHASCCHAPGLECKVKEHGIPQEQVTVACEEGWTLTGCSALPSHVLGAYAVDNTCVVRSRAVTAVAICCRSR 6u2x A 2.15 BS01 NAD A 1 I163 T164 F166 K190 G191 A192 P193 A227 G230 T231 F244 G246 S247 V250 V254 I161 T162 F164 K188 G189 A190 P191 A225 G228 T229 F242 G244 S245 V248 V252 1.2.1.31,1.2.1.3,1.2.1.8 P49419 31652343 TLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTGTFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ 6u3x B 2.64 BS01 PVV B 1 A328 S329 A330 P331 V333 T335 R357 C358 D360 R458 W461 R476 A161 S162 A163 P164 V166 T168 R190 C191 D193 R289 W292 R307 3.4.21.- Q8NBP7 31653597 SIPWNLERITPPRYRGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVPEEDASKCDSHGTHLAGVVSGRDAGVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVLNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHGWQLFCRTVWSAHSGPTRMATAIARCAPDEELLSCSSFSRSGKRRGERMEAQGGKLVCRAHNAFGGEGVYAIARCCLLPQANCSVHTAPPAEASMGTRVHCHQQGHVLTGCSSHWEVEDLQPNQCVGHREASIHASCCHAPGLECKVKEHGIPQEQVTVACEEGWTLTGCSALPSHVLGAYAVDNTCVVRSRAVTAVAICCRSR 6u7l A 2.75 BS01 CA A 1 Q287 C288 E321 A417 D419 Q240 C241 E274 A354 D356 4.2.1.42 P39829 TPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGAPAAVVPIRTIHNISLNPNFGGEVMVIGKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT 6u7l C 2.75 BS02 CA C 2 E479 E484 E409 E414 4.2.1.42 P39829 TPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLPAAVVPIRTIHNISLNPNFGGEVMVIGEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT 6u9x D 2.60 BS01 NUC H 1 S112 G113 P114 M115 R116 L132 Y197 R199 R219 N221 R222 L224 P226 I229 I232 S233 L234 K235 L274 Y275 Q276 W283 V285 V287 Y289 I326 L351 Q352 L355 R356 Y360 R364 S37 G38 P39 M40 R41 L57 Y111 R113 R133 N135 R136 L138 P140 I143 I146 S147 L148 K149 L188 Y189 Q190 W197 V199 V201 Y203 I240 L265 Q266 L269 R270 Y274 R278 B6SBM0 VHLSTIQLEKLSHPPARFDNSFVYKWQTKAALARKVSGPMREWAAELKYRTGVHIELEPTYPERLSENAVQWGAYETADDVDITVYLFGSERGIFNCHKLMEAAIQQDPVYVRLGIFRRLANSSEVEWLMLRRINRELRPPDIPPISLKLPGKWTLLYERYKEAAIRTLWEETGITVDASNVYPTGHLYQTVPQYYWRVPVRYFVAEVPSDIRVEGPQVVPLQYMRNWDARLLRQSPDPIDRAWAQLADPATGCAWMKASMIDQLQKPLRGDNYMAIRYTPPPYSNLQEVVGLG 6u9x A 2.60 BS01 NUC K 1 S112 M115 R116 L132 Y197 R199 R219 N221 R222 L224 I229 I232 S233 L234 K235 L274 Q276 W283 R284 V285 V287 Y289 I326 Q352 L355 R356 Y360 R364 S38 M41 R42 L58 Y111 R113 R133 N135 R136 L138 I143 I146 S147 L148 K149 L188 Q190 W197 R198 V199 V201 Y203 I240 Q266 L269 R270 Y274 R278 B6SBM0 VHLQQSTIQLEKLSHPPARFDSFVYKWQTKAALARKVSGPMREWAAELKYRTGVHIELEPTYPERLSENAQWGAYETADDVDITVYLFGSERGIFNCHKLMEAAIQQDPVYVRLGIFRRLANSSEVEWLMLRRINRELRPPDIPPISLKLPGKWTLLYERYKEAAIRTLWEETGITVDASNVYPTGHLYQTVPQYYWRVPVRYFVAEVPSDIRVEGPQVVPLQYMRNWDARLLRQSPDPIDRAWAQLADPATGCAWMKASMIDQLQKPLRGDNYMAIRYTPPPYSNLQEVVGLG 6uph A 2.70 BS01 NUC I 1 R177 W178 Q179 S180 I211 T212 R42 W43 Q44 S45 I76 T77 P36012 ELALYEIRKYQRSTDLLISKIPFARLVKEVTDEFTTKDQDLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDMQLARRIRGQF 6uph A 2.70 BS02 NUC J 1 L137 S154 I156 R160 R177 L2 S19 I21 R25 R42 P36012 ELALYEIRKYQRSTDLLISKIPFARLVKEVTDEFTTKDQDLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDMQLARRIRGQF 6uph B 2.70 BS02 NUC J 1 R36 R46 I47 G49 K80 T81 R12 R22 I23 G25 K56 T57 Q6CMU6 DNIQGITKPAIRRLARRGGVKRISGLIYEEVRNVLKTFLESVIRDAVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG 6uph C 2.70 BS01 NUC I 1 R18 R33 R2 R17 Q6CK59 SRSAKAGLTFPVGRVHRLLRKGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIH 6uph C 2.70 BS02 NUC J 1 R30 R43 I44 G45 S46 T77 R78 R14 R27 I28 G29 S30 T61 R62 Q6CK59 SRSAKAGLTFPVGRVHRLLRKGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIH 6uph D 2.70 BS01 NUC I 1 S60 Q61 K91 S92 T93 S27 Q28 K58 S59 T60 Q6CK60 RTKARKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERIATESSKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSS 6uph D 2.70 BS02 NUC J 1 K36 R38 K39 Y45 K3 R5 K6 Y12 Q6CK60 RTKARKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERIATESSKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSS 6uph E 2.70 BS01 NUC I 1 P134 L137 I156 R160 P2 L5 I24 R28 P36012 TPSELALYEIRKYQRSTDLLISKIPFARLVKEVTDEFTTKDQDLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDMQLARRIRGQFI 6uph E 2.70 BS02 NUC J 1 R177 W178 I211 T212 M214 R45 W46 I79 T80 M82 P36012 TPSELALYEIRKYQRSTDLLISKIPFARLVKEVTDEFTTKDQDLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDMQLARRIRGQFI 6uph H 2.70 BS01 NUC I 1 R38 K39 Y45 R1 K2 Y8 Q6CK60 RKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERIATESSKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSS 6uph H 2.70 BS02 NUC J 1 G58 S60 Q61 S92 T93 G21 S23 Q24 S55 T56 Q6CK60 RKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERIATESSKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSS 6urc A 2.20 BS01 QFV A 1 L577 V586 A597 K599 E612 V613 L616 Y628 I640 I642 E643 L644 C645 A646 A647 E651 L695 S710 D711 F712 L18 V27 A38 K40 E53 V54 L57 Y69 I81 I83 E84 L85 C86 A87 A88 E92 L136 S151 D152 F153 2.7.11.1,3.1.26.- O75460 31371506 ETSVVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLTYKGGSVRDLLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYYFH 6urc B 2.20 BS01 QFV B 1 L577 G578 A597 K599 E612 V613 I626 Y628 I640 I642 E643 L644 C645 A646 A647 E651 L695 S710 D711 F712 L18 G19 A38 K40 E53 V54 I67 Y69 I81 I83 E84 L85 C86 A87 A88 E92 L136 S151 D152 F153 2.7.11.1,3.1.26.- O75460 31371506 ETSVVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDYKGGSVRDLLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYYFH 6utp F 3.55 BS01 CO F 1 D82 H190 D81 H180 A0A0G9FES3 ATLATKKATLVAALKDLQRVTVAFSGGIDSTLVLKMALDVLGRDNVTAVVANSELFTDEEFDKAMSLAEELGANVQGTTLDYLSDDHIKNNTPDSWYYAKKMFYSRLNDIAANNGSAAVLDGMIKNKARSEAGARSLLQEADFFKTDVRALAQELGLTNWNKVASCSVSSRFPYGTTLTHDNIAQVMAAEKYLRSLGFPTVRVRFHNDIARIELPEARIGDFLVFNDRVNRQLQSLGFRYVTLDLGGFRS 6uts A 3.09 BS01 NI A 1 H57 H59 H101 H57 H59 H100 A0A4S5WTB9 MIYLRKANERGHANHGWLDSWHTFSFANYYDPNFMGFSALRVINDDVIEAGQGFGTHPHKDMEILTYVLEGTVEHQDSGNKEQVPAGEFQIMSAGTGIRHSEYNPSSTERLHLYQIWIMPEENGITPRYEQRRFAVQGKQLVLSPDARDGSLKVHQDMELYRWALLKDEQSVHQIAAERRVWIQVVKGNVTINGVKASTSDGLAIWDEQAISIHADSDSEVLLFDLPPV