5kiw A 3.41 BS01 ANP A 1 D205 I206 G207 P247 G248 T249 G250 K251 T252 L253 I380 H384 G408 A409 D185 I186 G187 P227 G228 T229 G230 K231 T232 L233 I360 H364 G388 A389 3.6.4.6 P55072 29238611 NRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEESWNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSN 5mwp A 1.82 BS01 ECV A 1 L769 N770 L772 A773 Q776 M807 S810 S811 L814 R817 F829 M845 C849 M852 L938 F941 C942 T945 V954 L35 N36 L38 A39 Q42 M73 S76 S77 L80 R83 F95 M111 C115 M118 L197 F200 C201 T204 V213 P08235 29474466 YFSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTKSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK 5mwy A 1.75 BS01 YNU A 1 L766 L769 N770 A773 Q776 W806 M807 S810 L814 R817 F829 M845 M852 L938 F941 C942 T945 F956 L32 L35 N36 A39 Q42 W72 M73 S76 L80 R83 F95 M111 M118 L198 F201 C202 T205 F216 P08235 29474466 YFSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK 5n56 A 2.07 BS01 MN A 1 H27 H81 D161 H165 H26 H80 D160 H164 1.15.1.1 Q2YT26 AFELPKLPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVEGTDLESKSIEEIVANLDSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKIKEQWGSLEEFKKEFADKAAARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGLDVWEHAYYLKYQNKRPDYIGAFWNVVNWEKVDELYNATK 5n57 A 2.30 BS01 MN A 1 H27 H81 D161 H165 H26 H80 D160 H164 1.15.1.1 W8UU58 AFKLPNLPYAYDALEPYIDQRTMEFHHDKHHNTYVTKLNATVEGTELEHQSLADMIANLDKVPEAMRMSVRNNGGGHFNHSLFWEILSPNSEEKGGVIDDIKAQWGTLDEFKNEFANKATTLFGSGWTWLVVNDGKLEIVTTPNQDNPLTEGKTPILLFDVWEHAYYLKYQNKRPDYMTAFWNIVNWKKVDELYQAAK 5n5i A 2.20 BS03 ZN A 3 S154 E156 S123 E125 Q9XAY4 EYPTVNEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEAEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSANVLYGGCAVHELSSTSAGNVADADLAEWPTSVERIQKHYPEAEVVIPGHGLPGGLDLLQHTANVVKAHKNRS 5n5i A 2.20 BS04 LMP A 1 F62 Y67 P68 W87 H179 E202 G209 N210 H240 F31 Y36 P37 W56 H148 E171 G178 N179 H209 Q9XAY4 EYPTVNEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEAEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSANVLYGGCAVHELSSTSAGNVADADLAEWPTSVERIQKHYPEAEVVIPGHGLPGGLDLLQHTANVVKAHKNRS 5n5l A 1.97 BS01 III B 1 G48 D128 F130 D131 I133 T134 D167 D170 E171 D202 G203 T204 V206 D234 G238 D239 I240 E243 R256 G16 D95 F97 D98 I100 T101 D134 D137 E138 D169 G170 T171 V173 D201 G205 D206 I207 E210 R223 2.7.11.1 P11309 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5n5l A 1.97 BS02 8NZ A 1 L44 F49 V52 A65 R122 L174 I185 D186 L12 F17 V20 A33 R89 L141 I152 D153 2.7.11.1 P11309 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5n5m A 2.21 BS02 8O8 A 1 G45 F49 A65 E121 R122 E171 N172 L174 D186 G13 F17 A33 E89 R90 E139 N140 L142 D154 2.7.11.1 P11309 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIGGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH 5n5o A 2.00 BS01 8O5 A 1 T26 H41 F140 N142 G143 S144 C145 H163 H164 M165 E166 D187 Q189 T26 H41 F140 N142 G143 S144 C145 H163 H164 M165 E166 D187 Q189 3.4.19.12,3.4.22.69,3.4.22.-,2.7.7.48,3.6.4.12,3.6.4.13,2.1.1.- P0C6X7 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ 5n6f A 1.12 BS02 GUN A 1 D102 Y106 D156 I201 Q203 G229 G230 M260 D92 Y96 D137 I181 Q183 G209 G210 M240 2.4.2.29 P28720 DRPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGAATVKALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMKQSEEGVTFKSHSRHMLSPERSIEIQHLLGSDIVMAFDETPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFAR 5n6v A 1.60 BS01 SUC A 1 D231 V434 P435 F436 Q437 Y438 W498 S505 D506 S508 D231 V434 P435 F436 Q437 Y438 W498 S505 D506 S508 2.4.1.4 Q9ZEU2 SPNSQYLKTRILDIYTPEQRAGIEKSEDWRQFSRRMHTHFPKLMNELDSVYGNNEALLPMLEMLLAQAWQSYSQRNSSLKDIDIARENNPDWILSNKQVGGVCYVDLFAGDLKGLKDKIPYFQELGLTYLHLMPLFKCPEGKSDGGYAVSSYRDVNPALGTIGDLREVIAALHEAGISAVVDFIFNHTSNEHEWAQRCAAGDPLFDNFYYIFPDRRMPDQYDRTLREIFPDQHPGGFSQLEDGRWVWTTFNSFQWDLNYSNPWVFRAMAGEMLFLANLGVDILRMDAVAFIWKQMGTSCENLPQAHALIRAFNAVMRIAAPAVFFKSEAIDHPDQVVQYIGQDECQIGYNPLQMALLWNTLATREVNLLHQALTYRHNLPEHTAWVNYVRSHDDIGWTFADEDAAYLGISGYDHRQFLNRFFVNRFDGSFARGVPFQYNPSTGDCRVSGTAAALVGLAQDDPHAVDRIKLLYSIALSTGGLPLIYLGDEVGTLNDDDWSQDSNKSDDSRWAHRPRYNEALYAQRNNPSTAAGQIYQDLRHMIAVRQSNPRFDGGRLVTFNTNNKHIIGYIRNNALLAFGNFSEYPQTVTAHTLQAMPFKAHDLIGGKTISLNQDLTLQPYQVMWLEIA 5n6v A 1.60 BS02 SUC A 2 L12 D13 Y15 T16 P17 R20 L12 D13 Y15 T16 P17 R20 2.4.1.4 Q9ZEU2 SPNSQYLKTRILDIYTPEQRAGIEKSEDWRQFSRRMHTHFPKLMNELDSVYGNNEALLPMLEMLLAQAWQSYSQRNSSLKDIDIARENNPDWILSNKQVGGVCYVDLFAGDLKGLKDKIPYFQELGLTYLHLMPLFKCPEGKSDGGYAVSSYRDVNPALGTIGDLREVIAALHEAGISAVVDFIFNHTSNEHEWAQRCAAGDPLFDNFYYIFPDRRMPDQYDRTLREIFPDQHPGGFSQLEDGRWVWTTFNSFQWDLNYSNPWVFRAMAGEMLFLANLGVDILRMDAVAFIWKQMGTSCENLPQAHALIRAFNAVMRIAAPAVFFKSEAIDHPDQVVQYIGQDECQIGYNPLQMALLWNTLATREVNLLHQALTYRHNLPEHTAWVNYVRSHDDIGWTFADEDAAYLGISGYDHRQFLNRFFVNRFDGSFARGVPFQYNPSTGDCRVSGTAAALVGLAQDDPHAVDRIKLLYSIALSTGGLPLIYLGDEVGTLNDDDWSQDSNKSDDSRWAHRPRYNEALYAQRNNPSTAAGQIYQDLRHMIAVRQSNPRFDGGRLVTFNTNNKHIIGYIRNNALLAFGNFSEYPQTVTAHTLQAMPFKAHDLIGGKTISLNQDLTLQPYQVMWLEIA 5n6v A 1.60 BS03 GLC A 1 H414 F417 H414 F417 2.4.1.4 Q9ZEU2 SPNSQYLKTRILDIYTPEQRAGIEKSEDWRQFSRRMHTHFPKLMNELDSVYGNNEALLPMLEMLLAQAWQSYSQRNSSLKDIDIARENNPDWILSNKQVGGVCYVDLFAGDLKGLKDKIPYFQELGLTYLHLMPLFKCPEGKSDGGYAVSSYRDVNPALGTIGDLREVIAALHEAGISAVVDFIFNHTSNEHEWAQRCAAGDPLFDNFYYIFPDRRMPDQYDRTLREIFPDQHPGGFSQLEDGRWVWTTFNSFQWDLNYSNPWVFRAMAGEMLFLANLGVDILRMDAVAFIWKQMGTSCENLPQAHALIRAFNAVMRIAAPAVFFKSEAIDHPDQVVQYIGQDECQIGYNPLQMALLWNTLATREVNLLHQALTYRHNLPEHTAWVNYVRSHDDIGWTFADEDAAYLGISGYDHRQFLNRFFVNRFDGSFARGVPFQYNPSTGDCRVSGTAAALVGLAQDDPHAVDRIKLLYSIALSTGGLPLIYLGDEVGTLNDDDWSQDSNKSDDSRWAHRPRYNEALYAQRNNPSTAAGQIYQDLRHMIAVRQSNPRFDGGRLVTFNTNNKHIIGYIRNNALLAFGNFSEYPQTVTAHTLQAMPFKAHDLIGGKTISLNQDLTLQPYQVMWLEIA 5n6v A 1.60 BS04 FRU A 1 R86 Q98 T128 G176 S178 R86 Q98 T128 G176 S178 2.4.1.4 Q9ZEU2 SPNSQYLKTRILDIYTPEQRAGIEKSEDWRQFSRRMHTHFPKLMNELDSVYGNNEALLPMLEMLLAQAWQSYSQRNSSLKDIDIARENNPDWILSNKQVGGVCYVDLFAGDLKGLKDKIPYFQELGLTYLHLMPLFKCPEGKSDGGYAVSSYRDVNPALGTIGDLREVIAALHEAGISAVVDFIFNHTSNEHEWAQRCAAGDPLFDNFYYIFPDRRMPDQYDRTLREIFPDQHPGGFSQLEDGRWVWTTFNSFQWDLNYSNPWVFRAMAGEMLFLANLGVDILRMDAVAFIWKQMGTSCENLPQAHALIRAFNAVMRIAAPAVFFKSEAIDHPDQVVQYIGQDECQIGYNPLQMALLWNTLATREVNLLHQALTYRHNLPEHTAWVNYVRSHDDIGWTFADEDAAYLGISGYDHRQFLNRFFVNRFDGSFARGVPFQYNPSTGDCRVSGTAAALVGLAQDDPHAVDRIKLLYSIALSTGGLPLIYLGDEVGTLNDDDWSQDSNKSDDSRWAHRPRYNEALYAQRNNPSTAAGQIYQDLRHMIAVRQSNPRFDGGRLVTFNTNNKHIIGYIRNNALLAFGNFSEYPQTVTAHTLQAMPFKAHDLIGGKTISLNQDLTLQPYQVMWLEIA 5npu A 3.50 BS01 MG A 1 D441 I466 N468 G470 D425 I450 N452 G454 TYTVGHYLATRLAQIGLKHHFAVAGDYNLVLLDQLLKNKDLEQVYCCNELNCGFSAEGYARANGVGAAVVTFSVGALSAFNAIGGAYAENLPVILISGAPNTNDHGSGHILHHTIGTTDYGYQLEMAKQITCAAVSITHAEDAPALIDHAIRTALREKKPAYIEIACNVAAQPCARPGPVSALLNEPTSDEETLKAAVEAALDFIEKREKPVLLVGGKLRAAGAEEAVVELADALGCAVATMAAAKSFFPEDHPGYVGTYWGEVSSPGVEEIVDWADGIICLGPVFNDYSTVGWTAWPKGENVVLVDPHHITVGGEEFTGIHLKDFLTALTERVPKKDATLDAADPNAPLTRAELCRQIQGLLNPNTTLIAETGDSWFNAMRMKLPHGARVELEMQWGHIGWSVPATFGYAVAEPERRNVLMVGDGSFQLTAQEVAQMVRRKLPIIIFLINNRGYTIEVKIHDGPYNNIKNWDYAGLMEVFNAEDGKGLGLKATTGGELAEAIKKALAHREGPTLIECVIDRDDCTPELVTWGKKVATANARPPQAI 5npu A 3.50 BS02 TPP A 1 D391 G414 H415 I416 G440 D441 G442 S443 L446 N468 G470 Y471 T472 I473 E474 D375 G398 H399 I400 G424 D425 G426 S427 L430 N452 G454 Y455 T456 I457 E458 TYTVGHYLATRLAQIGLKHHFAVAGDYNLVLLDQLLKNKDLEQVYCCNELNCGFSAEGYARANGVGAAVVTFSVGALSAFNAIGGAYAENLPVILISGAPNTNDHGSGHILHHTIGTTDYGYQLEMAKQITCAAVSITHAEDAPALIDHAIRTALREKKPAYIEIACNVAAQPCARPGPVSALLNEPTSDEETLKAAVEAALDFIEKREKPVLLVGGKLRAAGAEEAVVELADALGCAVATMAAAKSFFPEDHPGYVGTYWGEVSSPGVEEIVDWADGIICLGPVFNDYSTVGWTAWPKGENVVLVDPHHITVGGEEFTGIHLKDFLTALTERVPKKDATLDAADPNAPLTRAELCRQIQGLLNPNTTLIAETGDSWFNAMRMKLPHGARVELEMQWGHIGWSVPATFGYAVAEPERRNVLMVGDGSFQLTAQEVAQMVRRKLPIIIFLINNRGYTIEVKIHDGPYNNIKNWDYAGLMEVFNAEDGKGLGLKATTGGELAEAIKKALAHREGPTLIECVIDRDDCTPELVTWGKKVATANARPPQAI 5npu B 3.50 BS01 MG B 1 D441 N468 G470 T472 D423 N450 G452 T454 TYTVGHYLATRLAQIGLKHHFAVAGDYNLVLLDQLLKNKDLEQVYCCNELNCGFSAEGYARANGVGAAVVTFSVGALSAFNAIGGAYAENLPVILISGAPNTNDHGSGHILHHTIGTTDYGYQLEMAKQITCAAVSITHAEDAPALIDHAIRTALREKKPAYIEIACNVAAQPCARPGPVSALLNEPTSDEETLKAAVEAALDFIEKREKPVLLVGGKLRAAGAEEAVVELADALGCAVATMAAAKSFFPEDHPGYVGTYWGEVSSPGVEEIVDWADGIICLGPVFNDYSTVGWTAWPKGENVVLVDPHHITVGGEEFTGIHLKDFLTALTERVPKKDATLADPNAPLTRAELCRQIQGLLNPNTTLIAETGDSWFNAMRMKLPHGARVELEMQWGHIGWSVPATFGYAVAEPERRNVLMVGDGSFQLTAQEVAQMVRRKLPIIIFLINNRGYTIEVKIHDGPYNNIKNWDYAGLMEVFNAEDGKGLGLKATTGGELAEAIKKALAHREGPTLIECVIDRDDCTPELVTWGKKVATANARPPQAI 5npu C 3.50 BS02 TPP C 1 T389 G390 D391 G414 H415 I416 G440 D441 G442 S443 L446 N468 G470 Y471 T472 I473 E474 T373 G374 D375 G398 H399 I400 G424 D425 G426 S427 L430 N452 G454 Y455 T456 I457 E458 TYTVGHYLATRLAQIGLKHHFAVAGDYNLVLLDQLLKNKDLEQVYCCNELNCGFSAEGYARANGVGAAVVTFSVGALSAFNAIGGAYAENLPVILISGAPNTNDHGSGHILHHTIGTTDYGYQLEMAKQITCAAVSITHAEDAPALIDHAIRTALREKKPAYIEIACNVAAQPCARPGPVSALLNEPTSDEETLKAAVEAALDFIEKREKPVLLVGGKLRAAGAEEAVVELADALGCAVATMAAAKSFFPEDHPGYVGTYWGEVSSPGVEEIVDWADGIICLGPVFNDYSTVGWTAWPKGENVVLVDPHHITVGGEEFTGIHLKDFLTALTERVPKKDATLPAADPNAPLTRAELCRQIQGLLNPNTTLIAETGDSWFNAMRMKLPHGARVELEMQWGHIGWSVPATFGYAVAEPERRNVLMVGDGSFQLTAQEVAQMVRRKLPIIIFLINNRGYTIEVKIHDGPYNNIKNWDYAGLMEVFNAEDGKGLGLKATTGGELAEAIKKALAHREGPTLIECVIDRDDCTPELVTWGKKVATANARPPQAI 5nt4 A 1.90 BS02 97Z A 1 H1031 G1032 F1035 R1047 H1048 A1049 Y1050 Y1060 A1062 K1067 S1068 Y1071 H80 G81 F84 R96 H97 A98 Y99 Y109 A111 K116 S117 Y120 2.4.2.30 Q9H2K2 29374194 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSA 5nt4 B 1.90 BS02 97Z B 1 H1031 G1032 S1033 F1035 R1047 H1048 Y1050 Y1060 F1061 A1062 K1067 S1068 Y1071 I1075 H80 G81 S82 F84 R96 H97 Y99 Y109 F110 A111 K116 S117 Y120 I124 2.4.2.30 Q9H2K2 29374194 GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAM 5nty A 2.00 BS01 PLM A 1 K29 P32 L35 F36 L37 A55 A57 M73 M88 Y90 H104 R121 Y133 K29 P32 L35 F36 L37 A55 A57 M73 M88 Y90 H104 R121 Y133 P02753 29414511 ERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYC 5nu2 A 1.50 BS01 PLM A 1 K29 P32 L35 F36 L37 A55 M73 M88 Y90 H104 Y133 F135 K29 P32 L35 F36 L37 A55 M73 M88 Y90 H104 Y133 F135 P02753 29414511 ERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYC 5nu6 A 1.68 BS01 PLM A 1 K29 P32 L35 F36 L37 F45 A57 M73 M88 Y133 F135 F137 K29 P32 L35 F36 L37 F45 A57 M73 M88 Y133 F135 F137 P02753 29414511 ERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYC 5nu7 A 1.50 BS01 RTL A 1 L35 F36 V61 M73 M88 Y90 Q98 H104 F135 L35 F36 V61 M73 M88 Y90 Q98 H104 F135 P02753 29414511 ERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYC 5nua A 1.60 BS01 DAO A 1 K29 P32 F36 L37 A55 A57 M88 Y90 Y133 K29 P32 F36 L37 A55 A57 M88 Y90 Y133 P02753 29414511 ERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYC 5nwl A 3.93 BS01 MG A 1 T134 T165 D222 T114 T145 D202 Q06609 GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 5nwl A 3.93 BS02 ATP A 1 F129 R130 G132 K133 T134 Q135 R170 Q268 R310 I329 N330 A331 F109 R110 G112 K113 T114 Q115 R150 Q248 R272 I291 N292 A293 Q06609 GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 5nwl A 3.93 BS03 ATP B 1 S317 C319 L320 P321 E322 S279 C281 L282 P283 E284 Q06609 GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 5nwl C 3.93 BS01 MG C 1 T134 E163 T165 D222 T114 E143 T145 D202 Q06609 GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 5nwl C 3.93 BS02 ATP C 1 R130 G132 K133 T134 Q135 R170 Q268 R310 I329 N330 R110 G112 K113 T114 Q115 R150 Q248 R272 I291 N292 Q06609 GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 5nwl C 3.93 BS03 ATP D 1 S317 L320 P321 E322 S279 L282 P283 E284 Q06609 GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 5nwl D 3.93 BS02 ATP D 1 F129 R130 G132 K133 T134 Q135 R170 Q268 R310 I329 F109 R110 G112 K113 T114 Q115 R150 Q248 R273 I292 Q06609 GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 5nwl E 3.93 BS02 ATP E 1 R130 G132 K133 T134 Q135 R170 Q268 R310 R110 G112 K113 T114 Q115 R150 Q248 R272 Q06609 GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 5nwl H 3.93 BS01 MG H 1 T134 T165 T114 T145 Q06609 GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 5nwl I 3.93 BS02 ATP I 1 R130 G132 K133 T134 Q135 R170 Q268 R310 N330 R110 G112 K113 T114 Q115 R150 Q248 R271 N291 Q06609 GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 5nwl J 3.93 BS02 ATP J 1 R130 G132 K133 T134 Q135 R170 Q268 N330 A331 R110 G112 K113 T114 Q115 R150 Q248 N291 A292 Q06609 GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 5nwl K 3.93 BS03 ATP L 1 C319 L320 P321 E322 C281 L282 P283 E284 Q06609 GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 5oi2 A 2.20 BS01 MG A 1 D64 C65 N117 N120 D8 C9 N61 N64 A0A0U2K7W4 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNKKRKYSAGERIVDIIATDI 5oi2 A 2.20 BS02 MG A 2 P58 G59 W61 H78 P109 I204 P2 G3 W5 H22 P53 I127 A0A0U2K7W4 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNKKRKYSAGERIVDIIATDI 5oi2 A 2.20 BS03 MG A 3 Y83 I84 E85 V180 N184 Y27 I28 E29 V108 N112 A0A0U2K7W4 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNKKRKYSAGERIVDIIATDI 5oi2 A 2.20 BS04 MG A 4 E87 V88 K173 V176 Q177 E31 V32 K101 V104 Q105 A0A0U2K7W4 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNKKRKYSAGERIVDIIATDI 5oi5 A 2.40 BS01 9VK A 1 A169 E170 H171 T174 A97 E98 H99 T102 A0A0U2K7W4 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNKKRKYSAGERIVDIIATDI 5oi5 A 2.40 BS02 MG A 1 K71 H171 K15 H99 A0A0U2K7W4 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNKKRKYSAGERIVDIIATDI 5oi8 A 2.35 BS02 9VN A 1 Q95 L102 A124 A125 A128 A129 W132 Q39 L46 A68 A69 A72 A73 W76 I0BY59 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSAAVKAACWWAGIKQMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNKKRKYSAGERIVDIIATDI 5oia A 2.20 BS02 MG A 2 S123 A124 A125 S67 A68 A69 I0BY59 SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSAAVKAACWWAGIKQMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNKKRKYSAGERIVDIIATDI 5ol4 C 1.28 BS03 9XN C 1 H137 H139 A170 K220 H222 H249 H275 G280 C322 H323 R339 D363 A366 M367 H137 H139 A170 K220 H222 H249 H275 G280 C322 H323 R339 D363 A366 M367 3.5.1.5 A0A0H3YL32 28857549 MKINRQQYAESYGPTVGDQVRLADTDLWIEVEKDYTTYGDEANFGGGKVLREGMGENGTYTRTENVLDLLLTNALILDYTGIYKADIGVKDGYIVGIGKGGNPDIMDGVTPNMIVGTATEVIAAEGKIVTAGGIDTHVHFINPDQVDVALANGITTLFGGGTGPAEGSKATTVTPGPWNIEKMLKSTEGLPINVGILGKGHGSSIAPIMEQIDAGAAGLKIHEDWGATPASIDRSLTVADEADVQVAIHSDTLNEAGFLEDTLRAINGRVIHSFHVEGAGGGHAPDIMAMAGHPNVLPSSTNPTRPFTVNTIDEHLDMLMVCHHLKQNIPEDVAFADSRIRPETIAAEDILHDLGIISMMSTDALAMGRAGEMVLRTWQTADKMKKQRGPLAEEKNGSDNFRAKRYVSKYTINPAIAQGIAHEVGSIEEGKFADLVLWEPKFFGVKADRVIKGGIIAYAQIGDPSASIPTPQPVMGRRMYGTVGDLIHDTNITFMSKSSIQQGVPAKLGLKRRIGTVKNCRNIGKKDMKWNDVTTDIDINPETYEVKVDGEVLTCEPVKELPMAQRYFLF 5on7 A 3.35 BS01 PIO A 1 Y16 R24 T27 A28 N29 R62 H72 Y16 R24 T27 A28 N29 R62 H72 Q05785 29362354 MSKQFVRSAKNMMKGYSSTQVLVRDATANDSRTPSIDTLDDLAQRSYDSVDFFEIMDMLDKRLNDKGKYWRHVAKSLTVLDYLVRFGSENCVLWCRENFYVIKTLREFRHENESGFDEGQIIRVKAKELVSLLNDEERLREERSMNT 5oog A 1.33 BS01 A0B A 1 S111 F113 W116 R124 L125 H132 P151 P152 H153 S110 F112 W115 R123 L124 H131 P150 P151 H152 1.5.1.30,1.3.1.24 P30043 AVKKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAADVDKTVAGQDAVIVLLGTRNDLSPTTVMSEGARNIVAAMKAHGVDKVVACTSAFLLWDPTKVPPRLQAVTDDHIRMHKVLRESGLKYVAVMPPHIGDQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTDEYDGHSTYPSHQYQ 5oog A 1.33 BS02 NAP A 1 G10 A11 T12 G13 Q14 T15 R35 R39 D54 V55 L74 L75 G76 R78 V86 M87 C109 T110 S111 V128 H132 P151 P152 H153 I154 G9 A10 T11 G12 Q13 T14 R34 R38 D53 V54 L73 L74 G75 R77 V85 M86 C108 T109 S110 V127 H131 P150 P151 H152 I153 1.5.1.30,1.3.1.24 P30043 AVKKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAADVDKTVAGQDAVIVLLGTRNDLSPTTVMSEGARNIVAAMKAHGVDKVVACTSAFLLWDPTKVPPRLQAVTDDHIRMHKVLRESGLKYVAVMPPHIGDQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTDEYDGHSTYPSHQYQ 5ooh A 1.20 BS02 9ZZ A 1 T77 N79 L81 S111 F113 L125 V128 H153 T76 N78 L80 S110 F112 L124 V127 H152 1.5.1.30,1.3.1.24 P30043 AVKKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAADVDKTVAGQDAVIVLLGTRNDLSPTTVMSEGARNIVAAMKAHGVDKVVACTSAFLLWDPTKVPPRLQAVTDDHIRMHKVLRESGLKYVAVMPPHIGDQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTDEYDGHSTYPSHQYQ 5ovc A 1.55 BS01 III B 1 G590 F591 G592 F593 V594 L595 R596 G597 A598 K599 T602 Y618 E620 S621 D623 H652 V656 I659 R660 G12 F13 G14 F15 V16 L17 R18 G19 A20 K21 T24 Y40 E42 S43 D45 H74 V78 I81 R82 Q9JLU4 29473168 SVAILQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWKAGLRTGDFLIEVNGVNVVKVGHKQVVGLIRQGGNRLVMKVVSVT 5ovp A 1.50 BS01 III B 1 G590 F591 G592 F593 V594 L595 R596 G597 A598 K599 E620 H652 K653 V656 I659 R660 G12 F13 G14 F15 V16 L17 R18 G19 A20 K21 E42 H74 K75 V78 I81 R82 Q9JLU4 29473168 SVAILQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWKAGLRTGDFLIEVNGVNVVKVGHKQVVGLIRQGGNRLVMKVVSVT 5uqz A 1.15 BS01 CA A 1 S347 N349 E360 S224 N226 E237 Q8DTF1 NTAVADYQKAKAEFPQKQEQYNKDFEKYQSDVKEYEAQKAAYEQYKKEVAQGLASGRVEKAQGLVFINEPEAKLSIEGVNQYLTKEARQKHATEDILQQYNTDNYTASDFTQANPYDPKEDTWFKMKVGDQISVTYDNIVNSKYNDKKISKVKINYTLNSSTNNEGSALVNLFHDPTKTIFIGAQTSNAGRNDKISVTMQIIFYDENGNEIDLSGNNAIMSLSSLNHWTTKYGDHVEKVNLGDNEFVKIPGSSVDLHGNEIYSAKDNQYKANGATFNGDGADGWDAVNADGTPRAATAYYGAGAMTYKGEPFTFTVGGNDQNLPTTIWFATNSAVAVPKDPGAKPTPPEKPELK 5uti A 1.36 BS02 GGB A 1 D102 Y106 D156 C158 G229 G230 L231 M260 D92 Y96 D144 C146 G217 G218 L219 M248 2.4.2.29 P28720 RPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSTKQSEEGVTFKSHLDGSRHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFA 5utj A 1.55 BS02 AZA A 1 Y106 Q107 D156 Q203 G229 G230 M260 G261 Y97 Q98 D137 Q184 G210 G211 M241 G242 2.4.2.29 P28720 DRPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMTKQSEEGVTFKSRHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFA 5uzj A 3.30 BS01 8UV A 1 I82 G85 F87 G88 E89 V90 A103 K105 L107 M153 E154 Y155 M156 L205 A215 D216 F368 I77 G80 F82 G83 E84 V85 A98 K100 L102 M144 E145 Y146 M147 L196 A206 D207 F355 2.7.11.1 Q13464 SFETRFEKMDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEETFPIPKAFVGNQLPFVGFTYYSNRRY 5uzj B 3.30 BS01 8UV B 1 I82 R84 G85 G88 E89 V90 A103 K105 L107 M153 E154 Y155 M156 L205 A215 D216 F368 I78 R80 G81 G84 E85 V86 A99 K101 L103 M149 E150 Y151 M152 L201 A211 D212 F358 2.7.11.1 Q13464 MSFETRFEKMDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEETFPIPKAFVGNQLPFVGFTYYSN 5uzk A 2.30 BS01 III I 1 E127 F129 S130 R133 K168 P169 E170 F187 L198 C199 G200 T201 P202 E203 E230 Y235 P236 F239 A240 D241 I246 D328 Y330 E114 F116 S117 R120 K155 P156 E157 F174 L185 C186 G187 T188 P189 E190 E217 Y222 P223 F226 A227 D228 I233 D315 Y317 2.7.11.11 P17612 SVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 5uzk A 2.30 BS02 504 A 1 L49 G52 S53 F54 G55 R56 V57 A70 K72 V104 M120 E121 Y122 V123 D166 L173 T183 D184 G186 F187 F327 L36 G39 S40 F41 G42 R43 V44 A57 K59 V91 M107 E108 Y109 V110 D153 L160 T170 D171 G173 F174 F314 2.7.11.11 P17612 SVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 5uzp A 2.29 BS01 OAA A 1 H265 N269 H301 R356 F424 R428 H238 N242 H274 R329 F397 R401 2.3.3.1 O75390 ASSTNLKDILADLIPKEQARIKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEGLFWLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESNFARAYAQGISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSHNFTNMLGYTDHQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHGVLRKTDPRYTCQREFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFVDS 5v02 R 1.78 BS01 657 R 1 E54 V55 I63 F68 M71 M72 E53 V54 I62 F67 M70 M71 P0DP23 DQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 5v03 B 1.58 BS01 658 R 1 Q470 N474 A477 L480 Q67 N71 A74 L77 Q9H2S1 GRKLELTKADTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQLE 5v03 R 1.58 BS01 658 R 1 F19 D50 M51 E54 V55 I63 F68 M71 F17 D48 M49 E52 V53 I61 F66 M69 P0DP23 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 5v0w A 1.80 BS01 MYA A 1 Y28 K29 F30 W31 N94 Y95 V96 V160 N161 F162 L163 C164 V165 R170 S171 K172 R173 L174 A175 P176 T183 I186 W192 Q193 A194 Y196 T197 L202 Y393 Y3 K4 F5 W6 N69 Y70 V71 V135 N136 F137 L138 C139 V140 R145 S146 K147 R148 L149 A150 P151 T158 I161 W167 Q168 A169 Y171 T172 L177 Y368 2.3.1.97 A0A1G4HIY1 PDYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFSSLNSRLTMSRAIKLYRVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL 5v0w A 1.80 BS02 KFK A 1 V96 D98 F103 R104 F105 Y107 N161 T197 G199 Y211 H213 S319 Y334 N365 A366 L367 L388 L409 L410 V71 D73 F78 R79 F80 Y82 N136 T172 G174 Y186 H188 S294 Y309 N340 A341 L342 L363 L384 L385 2.3.1.97 A0A1G4HIY1 PDYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFSSLNSRLTMSRAIKLYRVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL 5v0w C 1.80 BS01 MYA C 1 Y28 K29 F30 W31 Y95 V96 V160 F162 L163 C164 V165 R170 S171 K172 R173 L174 A175 P176 I179 T183 I186 N187 W192 A194 Y196 T197 L202 Y393 Y4 K5 F6 W7 Y71 V72 V136 F138 L139 C140 V141 R146 S147 K148 R149 L150 A151 P152 I155 T159 I162 N163 W168 A170 Y172 T173 L178 Y360 2.3.1.97 A0A1G4HIY1 GPDYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFSRAIKLYRVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL 5v0w C 1.80 BS02 KFK C 1 V96 F103 R104 F105 Y107 N161 T197 G199 Y211 H213 S319 Y334 N365 A366 L367 L388 L409 L410 V72 F79 R80 F81 Y83 N137 T173 G175 Y187 H189 S286 Y301 N332 A333 L334 L355 L376 L377 2.3.1.97 A0A1G4HIY1 GPDYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFSRAIKLYRVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL 5v0x A 2.10 BS02 8RD A 1 V96 D98 F103 R104 F105 Y107 T197 Y211 F226 S319 L330 A332 Y334 V363 N365 A366 L367 L388 L409 L410 V71 D73 F78 R79 F80 Y82 T172 Y186 F201 S294 L305 A307 Y309 V338 N340 A341 L342 L363 L384 L385 2.3.1.97 A0A1G4HIY1 PDYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFSSLNSRLTMSRAIKLYRVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL 5v0x C 2.10 BS01 MYA C 1 Y28 K29 F30 W31 N94 Y95 V96 F162 L163 C164 V165 R170 S171 K172 R173 L174 A175 P176 I179 T183 I186 N187 W192 A194 Y196 T197 A198 L202 Y393 Y3 K4 F5 W6 N69 Y70 V71 F137 L138 C139 V140 R145 S146 K147 R148 L149 A150 P151 I154 T158 I161 N162 W167 A169 Y171 T172 A173 L177 Y356 2.3.1.97 A0A1G4HIY1 PDYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFIKLYRVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL 5v12 E 2.45 BS01 8QJ F 1 S47 F48 F134 K247 S26 F27 F113 K226 4.4.1.- A7UX13 GPLPFGNSLLKEFVLDPAYRNLNHGSFGTIPSAIQQKLRSYQTAAEARPCPFLRYQTPVLLDESRAAVANLLKVPVETVVFVANATMGVNTVLRNIVWSADGKDEILYFDTIFGACGKTIDYVIEDKRGIVSSRCIPLIYPAEDDDVVAAFRDAIKKSREEGKRPRLAVIDVVSSMPGVRFPFEDIVKICKEEEIISCVDGAQGIGMVDLKITETDPDFLISNCHKWLFTPRGCAVFYVPVRNQHLIRSTLPTSHGFVPQKSAFVSNFEFVGTVDNSPFFCVKDAIKWREEVLGGEERIMEYMTKLAREGGQKVAEILGTRVLENSTGTLIRCAMVNIALPFVVGEDPKAPVKLTEKEEKDVEGLYEIPHEEANMAFKWMYNVLQDEFNTFVPMTFHRRRFWARLSAQVYLEMSDFEWAGKTLKELCERVAKGEYK 5v12 F 2.45 BS01 8QJ F 1 R75 H276 F304 T307 R55 H256 F274 T277 4.4.1.- A7UX13 TGPLPFGNSLLKEFVLDPAYRNLNHGSFGTIPSAIQQKLRSYQTAAEARPCPFLRYQTPVLLDESRAAVANLLKVPVETVVFVANATMGVNTVLRNIVWSADGKDEILYFDTIFGACGKTIDYVIEDKRGIVSSRCIPLIYPAEDDDVVAAFRDAIKKSREEGKRPRLAVIDVVSSMPGVRFPFEDIVKICKEEEIISCVDGAQGIGMVDLKITETDPDFLISNCHKWLFTPRGCAVFYVPVRNQHLIRSTLPTSHGFVPQAGNKSAFVSNFEFVGTVDNSPFFCVKDAIKWREEVLGGEERIMEYMTKLAREGGQKVAEILGTRVLENSTGTLIRCAMVNIALPFVVGEDPKAPVKLTEKEEKDVEGLYEIPHEEANMAFKWMYNVLQDEFNTFVPMTFHRRRFWARLSAQVYLEMSDFEWAGKTLKELCERVAKGEYK 5v12 A 2.45 BS01 8QJ A 1 F134 K247 F113 K226 4.4.1.- A7UX13 GPLPFGNSLLKEFVLDPAYRNLNHGSFGTIPSAIQQKLRSYQTAAEARPCPFLRYQTPVLLDESRAAVANLLKVPVETVVFVANATMGVNTVLRNIVWSADGKDEILYFDTIFGACGKTIDYVIEDKRGIVSSRCIPLIYPAEDDDVVAAFRDAIKKSREEGKRPRLAVIDVVSSMPGVRFPFEDIVKICKEEEIISCVDGAQGIGMVDLKITETDPDFLISNCHKWLFTPRGCAVFYVPVRNQHLIRSTLPTSHGFVPQVGKSAFVSNFEFVGTVDNSPFFCVKDAIKWREEVLGGEERIMEYMTKLAREGGQKVAEILGTRVLENSTGTLIRCAMVNIALPFVVGEDPKAPVKLTEKEEKDVEGLYEIPHEEANMAFKWMYNVLQDEFNTFVPMTFHRRRFWARLSAQVYLEMSDFEWAGKTLKELCERVAKGEYKE 5v12 B 2.45 BS01 8QJ A 1 R75 H276 F304 R54 H255 F271 4.4.1.- A7UX13 GPLPFGNSLLKEFVLDPAYRNLNHGSFGTIPSAIQQKLRSYQTAAEARPCPFLRYQTPVLLDESRAAVANLLKVPVETVVFVANATMGVNTVLRNIVWSADGKDEILYFDTIFGACGKTIDYVIEDKRGIVSSRCIPLIYPAEDDDVVAAFRDAIKKSREEGKRPRLAVIDVVSSMPGVRFPFEDIVKICKEEEIISCVDGAQGIGMVDLKITETDPDFLISNCHKWLFTPRGCAVFYVPVRNQHLIRSTLPTSHGFVPQNKSAFVSNFEFVGTVDNSPFFCVKDAIKWREEVLGGEERIMEYMTKLAREGGQKVAEILGTRVLENSTGTLIRCAMVNIALPFVVGEDPKAPVKLTEKEEKDVEGLYEIPHEEANMAFKWMYNVLQDEFNTFVPMTFHRRRFWARLSAQVYLEMSDFEWAGKTLKELCERVAKGEYK 5v1x D 2.56 BS01 8VV C 1 R75 F304 R55 F281 4.4.1.- A7UX13 TGPLPFGNSLLKEFVLDPAYRNLNHGSFGTIPSAIQQKLRSYQTAAEARPCPFLRYQTPVLLDESRAAVANLLKVPVETVVFVANATMGVNTVLRNIVWSADGKDEILYFDTIFGACGKTIDYVIEDKRGIVSSRCIPLIYPAEDDDVVAAFRDAIKKSREEGKRPRLAVIDVVSSMPGVRFPFEDIVKICKEEEIISCVDGAQGIGMVDLKITETDPDFLISNCHKWLFTPRGCAVFYVPVRNQHLIRSTLPTSHGFVPQVFNPLVPAGNKSAFVSNFEFVGTVDNSPFFCVKDAIKWREEVLGGEERIMEYMTKLAREGGQKVAEILGTRVLENSTGTLIRCAMVNIALPFVVGEDPKAPVKLTEKEEKDVEGLYEIPHEEANMAFKWMYNVLQDEFNTFVPMTFHRRRFWARLSAQVYLEMSDFEWAGKTLKELCERVAKGEYK 5v1x C 2.56 BS01 8VV C 1 S47 F134 Q224 K247 R438 S26 F113 Q203 K226 R406 4.4.1.- A7UX13 GPLPFGNSLLKEFVLDPAYRNLNHGSFGTIPSAIQQKLRSYQTAAEARPCPFLRYQTPVLLDESRAAVANLLKVPVETVVFVANATMGVNTVLRNIVWSADGKDEILYFDTIFGACGKTIDYVIEDKRGIVSSRCIPLIYPAEDDDVVAAFRDAIKKSREEGKRPRLAVIDVVSSMPGVRFPFEDIVKICKEEEIISCVDGAQGIGMVDLKITETDPDFLISNCHKWLFTPRGCAVFYVPVRNQHLIRSTLPTSHGFVPQVNKSAFVSNFEFVGTVDNSPFFCVKDAIKWREEVLGGEERIMEYMTKLAREGGQKVAEILGTRVLENSTGTLIRCAMVNIALPFVVGEDPKAPVKLTEKEEKDVEGLYEIPHEEANMAFKWMYNVLQDEFNTFVPMTFHRRRFWARLSAQVYLEMSDFEWAGKTLKELCERVAKGEYK 5v1x A 2.56 BS01 8VV A 1 G46 S47 F134 S196 Q224 K247 R438 G25 S26 F113 S175 Q203 K226 R407 4.4.1.- A7UX13 GPLPFGNSLLKEFVLDPAYRNLNHGSFGTIPSAIQQKLRSYQTAAEARPCPFLRYQTPVLLDESRAAVANLLKVPVETVVFVANATMGVNTVLRNIVWSADGKDEILYFDTIFGACGKTIDYVIEDKRGIVSSRCIPLIYPAEDDDVVAAFRDAIKKSREEGKRPRLAVIDVVSSMPGVRFPFEDIVKICKEEEIISCVDGAQGIGMVDLKITETDPDFLISNCHKWLFTPRGCAVFYVPVRNQHLIRSTLPTSHGFVPQVGNKSAFVSNFEFVGTVDNSPFFCVKDAIKWREEVLGGEERIMEYMTKLAREGGQKVAEILGTRVLENSTGTLIRCAMVNIALPFVVGEDPKAPVKLTEKEEKDVEGLYEIPHEEANMAFKWMYNVLQDEFNTFVPMTFHRRRFWARLSAQVYLEMSDFEWAGKTLKELCERVAKGEYK 5v26 A 1.79 BS02 FE2 A 2 C125 C128 C162 C165 Q167 C125 C128 C162 C165 Q167 1.13.11.6 Q1LCS4 MLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERADLKEGDIFLLPPHVRHSHQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSIVTDLPPLFESFYASEDKRRCPHCGQVHPG 5v2d A 1.90 BS01 FE A 1 H168 H219 H284 H475 H175 H226 H291 H482 W8QAY8 LVPRGSHMSIPFPQTPEFSGALYKPSRIEAEVFDLEIEGVLPASIHGTFYQVAPDPQYPPMLGTDIFFNGDGMVSGFHFANGKVSLRRRYVQTDRLLAQRREGRSLNGVYRNAFTNDSLAAKNNTTANTSVIPHNGVLLALKEDALPWAMDLETLETLGEWTFDGQIKSATFTAHPKLDPATGNLLAFSYEAKGDGTPDLVYFELSPDGKLLHEIWFQAPYAAMVHDFAATERYVVFPLIPLTVDVERMKNGGPHFQWQPDLPQLFAVVPRNGRAQDVRWFKGPMDGFQGHTLNAFDEDGKVYVDMPVTGGNIFYFFPQADGHVPPPETLAACLMRWTFDLNSGRDEVEPQPLTDYPCEFPRCDDRYIGRQYAHGFLLAFDPERPYNPANGPIPFQFFNLLVHLNLKTGLSDAWFPGDSGCFQEPIFIPRSADAEEADGYVVALLNLIAEERSELVVLDSRDMASGPIARIRIPFRMRMSLHGCWAPG 5v37 A 1.42 BS05 8WD A 1 C180 N181 S182 F183 T184 M190 E192 I237 Y239 L240 D241 Y257 V368 C178 N179 S180 F181 T182 M188 E190 I235 Y237 L238 D239 Y255 V366 2.1.1.43 Q9H7B4 PLKVEKFATANRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIR 5v3j E 2.06 BS01 NUC A 1 L408 R411 F428 R430 H433 R436 H437 I440 R457 Y458 Q461 K510 H517 R520 H521 S523 V524 K538 F540 R541 R542 E545 R548 H549 F568 E573 R576 H577 V580 R585 K594 I597 R598 E601 K622 F624 R626 E629 R632 H633 L47 R50 F67 R69 H72 R75 H76 I79 R96 Y97 Q100 K149 H156 R159 H160 S162 V163 K177 F179 R180 R181 E184 R187 H188 F207 E212 R215 H216 V219 R224 K233 I236 R237 E240 K261 F263 R265 E268 R271 H272 E9PYI1 PHKCKECGKAFHTPSQLSHHQKLHVGEKPYKCQECGKAFPSNAQLSLHHRVHTDEKCFECKECGKAFMRPSHLLRHQRIHTGEKPHKCKECGKAFRYDTQLSLHLLTHAGARRFECKDCDKVYSCASQLALHQMSHTGEKPHKCKECGKGFISDSHLLRHQSVHTGETPYKCKECGKGFRRGSELARHQRAHSGDKPYKCKECGKSFTCTTELFRHQKVHTGDRPHKCKECGKAFIRRSELTHHERSHSGEKPYECKECGKTFGRGSELSRHQKIHT 5v3j E 2.06 BS02 NUC B 1 S402 Q405 R430 S432 D459 C486 A487 S488 S514 S516 H517 T571 T572 F575 R576 K579 H587 R599 S600 R626 S628 S631 R632 K635 S41 Q44 R69 S71 D98 C125 A126 S127 S153 S155 H156 T210 T211 F214 R215 K218 H226 R238 S239 R265 S267 S270 R271 K274 E9PYI1 PHKCKECGKAFHTPSQLSHHQKLHVGEKPYKCQECGKAFPSNAQLSLHHRVHTDEKCFECKECGKAFMRPSHLLRHQRIHTGEKPHKCKECGKAFRYDTQLSLHLLTHAGARRFECKDCDKVYSCASQLALHQMSHTGEKPHKCKECGKGFISDSHLLRHQSVHTGETPYKCKECGKGFRRGSELARHQRAHSGDKPYKCKECGKSFTCTTELFRHQKVHTGDRPHKCKECGKAFIRRSELTHHERSHSGEKPYECKECGKTFGRGSELSRHQKIHT 5v3j E 2.06 BS03 ZN E 1 C365 C368 H381 H385 C4 C7 H20 H24 E9PYI1 PHKCKECGKAFHTPSQLSHHQKLHVGEKPYKCQECGKAFPSNAQLSLHHRVHTDEKCFECKECGKAFMRPSHLLRHQRIHTGEKPHKCKECGKAFRYDTQLSLHLLTHAGARRFECKDCDKVYSCASQLALHQMSHTGEKPHKCKECGKGFISDSHLLRHQSVHTGETPYKCKECGKGFRRGSELARHQRAHSGDKPYKCKECGKSFTCTTELFRHQKVHTGDRPHKCKECGKAFIRRSELTHHERSHSGEKPYECKECGKTFGRGSELSRHQKIHT 5v3j E 2.06 BS13 MG E 1 C477 C480 C116 C119 E9PYI1 PHKCKECGKAFHTPSQLSHHQKLHVGEKPYKCQECGKAFPSNAQLSLHHRVHTDEKCFECKECGKAFMRPSHLLRHQRIHTGEKPHKCKECGKAFRYDTQLSLHLLTHAGARRFECKDCDKVYSCASQLALHQMSHTGEKPHKCKECGKGFISDSHLLRHQSVHTGETPYKCKECGKGFRRGSELARHQRAHSGDKPYKCKECGKSFTCTTELFRHQKVHTGDRPHKCKECGKAFIRRSELTHHERSHSGEKPYECKECGKTFGRGSELSRHQKIHT 5v3j F 2.06 BS02 NUC D 1 S402 Q405 R430 T460 C486 A487 S488 L492 S514 S516 H517 T571 T572 F575 R576 K579 H587 R598 R599 S600 G627 S628 S631 R632 S41 Q44 R69 T99 C125 A126 S127 L131 S153 S155 H156 T210 T211 F214 R215 K218 H226 R237 R238 S239 G266 S267 S270 R271 E9PYI1 PHKCKECGKAFHTPSQLSHHQKLHVGEKPYKCQECGKAFPSNAQLSLHHRVHTDEKCFECKECGKAFMRPSHLLRHQRIHTGEKPHKCKECGKAFRYDTQLSLHLLTHAGARRFECKDCDKVYSCASQLALHQMSHTGEKPHKCKECGKGFISDSHLLRHQSVHTGETPYKCKECGKGFRRGSELARHQRAHSGDKPYKCKECGKSFTCTTELFRHQKVHTGDRPHKCKECGKAFIRRSELTHHERSHSGEKPYECKECGKTFGRGSELSRHQKIHTG 5v3j F 2.06 BS13 MG F 1 C477 C480 D481 C116 C119 D120 E9PYI1 PHKCKECGKAFHTPSQLSHHQKLHVGEKPYKCQECGKAFPSNAQLSLHHRVHTDEKCFECKECGKAFMRPSHLLRHQRIHTGEKPHKCKECGKAFRYDTQLSLHLLTHAGARRFECKDCDKVYSCASQLALHQMSHTGEKPHKCKECGKGFISDSHLLRHQSVHTGETPYKCKECGKGFRRGSELARHQRAHSGDKPYKCKECGKSFTCTTELFRHQKVHTGDRPHKCKECGKAFIRRSELTHHERSHSGEKPYECKECGKTFGRGSELSRHQKIHTG 5v3m C 2.09 BS01 NUC A 1 L408 R411 F428 R430 H433 R436 H437 R457 Y458 Q461 S496 K501 F512 H517 R520 H521 S523 F540 R541 R542 E545 R548 F568 T572 E573 R576 H577 V580 R585 R598 E601 F624 R626 E629 R632 H633 I636 L47 R50 F67 R69 H72 R75 H76 R96 Y97 Q100 S135 K140 F151 H156 R159 H160 S162 F179 R180 R181 E184 R187 F207 T211 E212 R215 H216 V219 R224 R237 E240 F263 R265 E268 R271 H272 I275 E9PYI1 PHKCKECGKAFHTPSQLSHHQKLHVGEKPYKCQECGKAFPSNAQLSLHHRVHTDEKCFECKECGKAFMRPSHLLRHQRIHTGEKPHKCKECGKAFRYDTQLSLHLLTHAGARRFECKDCDKVYSCASQLALHQMSHTGEKPHKCKECGKGFISDSHLLRHQSVHTGETPYKCKECGKGFRRGSELARHQRAHSGDKPYKCKECGKSFTCTTELFRHQKVHTGDRPHKCKECGKAFIRRSELTHHERSHSGEKPYECKECGKTFGRGSELSRHQKIHT 5v3m C 2.09 BS02 NUC B 1 S402 A404 Q405 R430 P431 S432 R436 D459 T460 C486 A487 S488 S514 S516 H517 T571 T572 F575 R576 R598 S600 R626 S628 S631 R632 S41 A43 Q44 R69 P70 S71 R75 D98 T99 C125 A126 S127 S153 S155 H156 T210 T211 F214 R215 R237 S239 R265 S267 S270 R271 E9PYI1 PHKCKECGKAFHTPSQLSHHQKLHVGEKPYKCQECGKAFPSNAQLSLHHRVHTDEKCFECKECGKAFMRPSHLLRHQRIHTGEKPHKCKECGKAFRYDTQLSLHLLTHAGARRFECKDCDKVYSCASQLALHQMSHTGEKPHKCKECGKGFISDSHLLRHQSVHTGETPYKCKECGKGFRRGSELARHQRAHSGDKPYKCKECGKSFTCTTELFRHQKVHTGDRPHKCKECGKAFIRRSELTHHERSHSGEKPYECKECGKTFGRGSELSRHQKIHT 5v3m C 2.09 BS12 ZN C 10 C617 E619 C620 H633 H637 C256 E258 C259 H272 H276 E9PYI1 PHKCKECGKAFHTPSQLSHHQKLHVGEKPYKCQECGKAFPSNAQLSLHHRVHTDEKCFECKECGKAFMRPSHLLRHQRIHTGEKPHKCKECGKAFRYDTQLSLHLLTHAGARRFECKDCDKVYSCASQLALHQMSHTGEKPHKCKECGKGFISDSHLLRHQSVHTGETPYKCKECGKGFRRGSELARHQRAHSGDKPYKCKECGKSFTCTTELFRHQKVHTGDRPHKCKECGKAFIRRSELTHHERSHSGEKPYECKECGKTFGRGSELSRHQKIHT 5vbs A 1.75 BS01 NUC B 1 Y64 P100 R116 K120 Y41 P77 R88 K92 2.7.7.49,2.7.7.7 P03355 28752992 TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLGIKPHIQRLLDQGILVPCQSPWNTPLLPVKDYRPVQDLREVNKRVEDIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPSGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR 5vmo A 1.70 BS01 III B 1 V29 S32 S34 L35 T38 F42 R44 P46 N47 E50 I51 N54 I55 S57 D58 N62 W63 G64 R65 L67 I68 L69 I72 L118 V26 S29 S31 L32 T35 F39 R41 P43 N44 E47 I48 N51 I52 S54 D55 N59 W60 G61 R62 L64 I65 L66 I69 L115 Q5GAF0 INFSALLRGERMCPLTREIHSQMLIVTKSYSLVETFRAFPRLPNILEIGNNIVSDGNLNWGRILILLGISQLYFTKSESESERTQITEQLERFFRQDAISNWIASNGGWVTCASL 5vxn A 3.38 BS01 NUC E 1 S152 K154 R177 S178 K180 T181 S184 Q185 S144 K146 R169 S170 K172 T173 S176 Q177 P0DMC7 NNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKIKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVT 5vxn A 3.38 BS02 NUC F 1 L167 V168 T169 S183 K186 K187 L159 V160 T161 S175 K178 K179 P0DMC7 NNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKIKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVT 5vxn B 3.38 BS01 NUC E 1 L167 V168 T169 K180 S183 K186 K187 L151 V152 T153 K164 S167 K170 K171 P0DMC7 NNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKESVSRLLEKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSS 5vxn B 3.38 BS02 NUC F 1 S152 P153 K154 R177 S178 K180 T181 S184 Q185 S136 P137 K138 R161 S162 K164 T165 S168 Q169 P0DMC7 NNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKESVSRLLEKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSS 5w0f A 1.60 BS01 9U7 A 1 P1106 L1109 P1110 F1111 V1115 L1120 I1122 N1168 R1173 V1174 F1177 P24 L27 P28 F29 V33 L38 I40 N86 R91 V92 F95 2.3.1.48 Q92793 28892380 KIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSL 5w43 A 3.15 BS01 NUC E 1 S152 K154 R177 S178 K180 T181 Q185 S145 K147 R170 S171 K173 T174 Q178 P0DMC7 NNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKIDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVT 5w43 A 3.15 BS02 NUC F 1 L167 V168 T169 I179 K180 S183 K186 K187 L160 V161 T162 I172 K173 S176 K179 K180 P0DMC7 NNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKIDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVT 5wjq D 2.79 BS01 NUC A 1 R411 K426 F428 R430 H433 R436 H437 I440 Y458 Q461 K482 S496 K501 H517 R520 H521 S523 V524 K538 F540 R541 R542 E545 R548 H549 F568 R576 H577 V580 R585 K594 R598 E601 S608 F624 R626 E629 R632 H633 R654 H657 Q660 H661 R26 K41 F43 R45 H48 R51 H52 I55 Y73 Q76 K97 S111 K116 H132 R135 H136 S138 V139 K153 F155 R156 R157 E160 R163 H164 F183 R191 H192 V195 R200 K209 R213 E216 S223 F239 R241 E244 R247 H248 R269 H272 Q275 H276 E9PYI1 GSEKPYKCQECGKAFPSNAQLSLHHRVHTDEKCFECKECGKAFMRPSHLLRHQRIHTGEKPHKCKECGKAFRYDTQLSLHLLTHAGARRFECKDCDKVYSCASQLALHQMSHTGEKPHKCKECGKGFISDSHLLRHQSVHTGETPYKCKECGKGFRRGSELARHQRAHSGDKPYKCKECGKSFTCTTELFRHQKVHTGDRPHKCKECGKAFIRRSELTHHERSHSGEKPYECKECGKTFGRGSELSRHQKIHTGEKPYKCQQCGKAFIRGSHLTQHQRIHT 5wjq D 2.79 BS02 NUC B 1 S402 A404 Q405 R430 D459 C486 S488 S514 S516 H517 R520 T572 F575 R576 K579 R599 R626 S628 S631 R654 S17 A19 Q20 R45 D74 C101 S103 S129 S131 H132 R135 T187 F190 R191 K194 R214 R241 S243 S246 R269 E9PYI1 GSEKPYKCQECGKAFPSNAQLSLHHRVHTDEKCFECKECGKAFMRPSHLLRHQRIHTGEKPHKCKECGKAFRYDTQLSLHLLTHAGARRFECKDCDKVYSCASQLALHQMSHTGEKPHKCKECGKGFISDSHLLRHQSVHTGETPYKCKECGKGFRRGSELARHQRAHSGDKPYKCKECGKSFTCTTELFRHQKVHTGDRPHKCKECGKAFIRRSELTHHERSHSGEKPYECKECGKTFGRGSELSRHQKIHTGEKPYKCQQCGKAFIRGSHLTQHQRIHT 5wpp A 1.70 BS01 CA A 1 G37 E39 E95 N98 D216 G11 E13 E69 N72 D190 A0A076NBW8 SVVSIPINNAGFEDPFIEVVDDYTVDTPPGWTTYNPNNLVPEKRTTMTSNNGVGYVGPGTQFYNQLAPEGRNIGYIYLAQKPGSGVAGFEQILDATLEPDTKYTLMVDVGNFGGEFQKISLAGFPGYRVELLAGDTVLAADHNNLYIKDGEFKTSTVTFTATPDNPYLDQKLGIRLINLLQGTFSGLDFDNVRLTVEPA 5wpp A 1.70 BS02 CA A 2 N137 F138 L147 A148 G149 D175 N111 F112 L121 A122 G123 D149 A0A076NBW8 SVVSIPINNAGFEDPFIEVVDDYTVDTPPGWTTYNPNNLVPEKRTTMTSNNGVGYVGPGTQFYNQLAPEGRNIGYIYLAQKPGSGVAGFEQILDATLEPDTKYTLMVDVGNFGGEFQKISLAGFPGYRVELLAGDTVLAADHNNLYIKDGEFKTSTVTFTATPDNPYLDQKLGIRLINLLQGTFSGLDFDNVRLTVEPA 5wpp A 1.70 BS03 CA A 3 D48 Y49 D22 Y23 A0A076NBW8 SVVSIPINNAGFEDPFIEVVDDYTVDTPPGWTTYNPNNLVPEKRTTMTSNNGVGYVGPGTQFYNQLAPEGRNIGYIYLAQKPGSGVAGFEQILDATLEPDTKYTLMVDVGNFGGEFQKISLAGFPGYRVELLAGDTVLAADHNNLYIKDGEFKTSTVTFTATPDNPYLDQKLGIRLINLLQGTFSGLDFDNVRLTVEPA 5x1o A 1.90 BS01 I3P A 1 R81 L82 Q123 Y124 R64 L65 Q106 Y107 P09038 KDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSA 5x1o A 1.90 BS02 I3P A 2 K77 E78 R81 L83 S85 K60 E61 R64 L66 S68 P09038 KDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSA 5x7j A 1.84 BS01 CA A 1 G15 K16 T17 T18 G14 K15 T16 T17 2.7.4.9 Q5SHX3 PGLFLTLEGLDGSGKTTQARRLAAFLEAQGRPVLLTREPGGGLPEVRSLQELSPEAEYLLFSADRAEHVRKVILPGLAAGKVVISDRYLDSSLAYQGYGRGLPLPWLREVAREATRGLKPRLTFLLDLPPEAALRRVRLGLEFFRRVREGYLALARAEPGRFVVLDATLPEEEIARAIQAHLRPLLP 5x7j A 1.84 BS02 CA A 2 G10 L11 L130 D131 L132 G9 L10 L126 D127 L128 2.7.4.9 Q5SHX3 PGLFLTLEGLDGSGKTTQARRLAAFLEAQGRPVLLTREPGGGLPEVRSLQELSPEAEYLLFSADRAEHVRKVILPGLAAGKVVISDRYLDSSLAYQGYGRGLPLPWLREVAREATRGLKPRLTFLLDLPPEAALRRVRLGLEFFRRVREGYLALARAEPGRFVVLDATLPEEEIARAIQAHLRPLLP 5x7j A 1.84 BS03 CA A 3 Y62 S66 R69 L93 A115 A118 Y58 S62 R65 L89 A111 A114 2.7.4.9 Q5SHX3 PGLFLTLEGLDGSGKTTQARRLAAFLEAQGRPVLLTREPGGGLPEVRSLQELSPEAEYLLFSADRAEHVRKVILPGLAAGKVVISDRYLDSSLAYQGYGRGLPLPWLREVAREATRGLKPRLTFLLDLPPEAALRRVRLGLEFFRRVREGYLALARAEPGRFVVLDATLPEEEIARAIQAHLRPLLP 5x7j A 1.84 BS04 CA A 4 T7 E9 Y92 D94 T127 T6 E8 Y88 D90 T123 2.7.4.9 Q5SHX3 PGLFLTLEGLDGSGKTTQARRLAAFLEAQGRPVLLTREPGGGLPEVRSLQELSPEAEYLLFSADRAEHVRKVILPGLAAGKVVISDRYLDSSLAYQGYGRGLPLPWLREVAREATRGLKPRLTFLLDLPPEAALRRVRLGLEFFRRVREGYLALARAEPGRFVVLDATLPEEEIARAIQAHLRPLLP 5x7j A 1.84 BS05 CA A 5 Q19 R22 L23 A186 I189 Q18 R21 L22 A175 I178 2.7.4.9 Q5SHX3 PGLFLTLEGLDGSGKTTQARRLAAFLEAQGRPVLLTREPGGGLPEVRSLQELSPEAEYLLFSADRAEHVRKVILPGLAAGKVVISDRYLDSSLAYQGYGRGLPLPWLREVAREATRGLKPRLTFLLDLPPEAALRRVRLGLEFFRRVREGYLALARAEPGRFVVLDATLPEEEIARAIQAHLRPLLP 5x7j B 1.84 BS02 CA B 2 L11 D12 Y99 R143 L147 F155 L10 D11 Y98 R142 L146 F154 2.7.4.9 Q5SHX3 PGLFLTLEGLDGSGKTTQARRLAAFLEAQGRPVLLTREPGGGLPEVRSLLLTQELSPEAEYLLFSADRAEHVRKVILPGLAAGKVVISDRYLDSSLAYQGYGRGLPLPWLREVAREATRGLKPRLTFLLDLPPEAALRRVRRPDRLEGLGLEFFRRVREGYLALARAEPGRFVVLDATLPEEEIARAIQAHLRPLLP 5x7j B 1.84 BS04 CA B 4 Q19 R22 L23 A186 I189 Q190 Q18 R21 L22 A185 I188 Q189 2.7.4.9 Q5SHX3 PGLFLTLEGLDGSGKTTQARRLAAFLEAQGRPVLLTREPGGGLPEVRSLLLTQELSPEAEYLLFSADRAEHVRKVILPGLAAGKVVISDRYLDSSLAYQGYGRGLPLPWLREVAREATRGLKPRLTFLLDLPPEAALRRVRRPDRLEGLGLEFFRRVREGYLALARAEPGRFVVLDATLPEEEIARAIQAHLRPLLP 5x7j B 1.84 BS05 CA B 5 E39 P40 F65 D68 R69 E38 P39 F64 D67 R68 2.7.4.9 Q5SHX3 PGLFLTLEGLDGSGKTTQARRLAAFLEAQGRPVLLTREPGGGLPEVRSLLLTQELSPEAEYLLFSADRAEHVRKVILPGLAAGKVVISDRYLDSSLAYQGYGRGLPLPWLREVAREATRGLKPRLTFLLDLPPEAALRRVRRPDRLEGLGLEFFRRVREGYLALARAEPGRFVVLDATLPEEEIARAIQAHLRPLLP 5x8o A 2.80 BS01 GTP A 1 R93 A94 Q95 I99 P102 R103 R123 V127 G128 C129 L206 T208 S210 D211 K214 R91 A92 Q93 I97 P100 R101 R121 V125 G126 C127 L204 T206 S208 D209 K212 1.1.1.205 Q57ZS7 FNESASIPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMAREGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAREGLNWKGRVGGVGCLLVVNCKNERKLLGIITRHDLKLADESTTVESLMTPVDKMVVSTNTSISLEEVTHLMRKGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIRLVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDIIAGNIASAEAAEALIDAGADGLKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAGADTVMLGNMLAGTDEAPGACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGA 5x9i A 1.50 BS01 OOA A 1 S1 R16 A18 F26 I64 E66 F70 G75 A87 L88 S89 L153 F277 S1 R16 A18 F26 I64 E66 F70 G75 A87 L88 S89 L153 F277 3.5.1.24 A3QAQ5 SSRLVTETQYGTMLMRTADWVSTAPFDGHMSVFPVGTERTMRGQVAEYQQAMTKWQTKYHTLSIEEHGAFGGLSGQTSNEKGLSVMALSQHDSEPYLSQHKDNGAPAVNTADVVSFITERYATTAEVKAALDNGEFQIAWASAPNGMEHAAPLHYSVVDADGNIMLIQLVKGGEQKIYLGDAESDLRVKTNDPLQEKHREYMQQFDLKDPSVATKMPWSIGGLERNSRLLAMSTHMDLEGLSYTETVARQKGTFDAAALVPFGVQDPKTGEDYPSFFSMQYNLDNGDIWFRSLMSGKEIKFNLEDTKQFKTPMHADIMAQVDKGAQTITWSKM 5x9i B 1.50 BS01 OOA B 1 S1 R16 A18 I64 E66 G75 A87 L88 S89 L153 S1 R16 A18 I64 E66 G75 A87 L88 S89 L153 3.5.1.24 A3QAQ5 SSRLVTETQYGTMLMRTADWVSTAPFDGHMSVFPVGTERTMRGQVAEYQQAMTKWQTKYHTLSIEEHGAFGGLSGQTSNEKGLSVMALSQHDSEPYLSQHKDNGAPAVNTADVVSFITERYATTAEVKAALDNGEFQIAWASAPNGMEHAAPLHYSVVDADGNIMLIQLVKGGEQKIYLGDAESDLRVKTNDPLQEKHREYMQQFDLKDPSVATKMPWSIGGLERNSRLLAMSTHMDLEGLSYTETVARQKGTFDAAALVPFGVQDPKTGEDYPSFFSMQYNLDNGDIWFRSLMSGKEIKFNLEDTKQFKTPMHADIMAQVDKGAQTITWSKM 5xig A 2.41 BS01 ANP A 1 R470 E472 F479 L480 R481 T482 F485 W487 Q555 T592 R594 R134 E136 F143 L144 R145 T146 F149 W151 Q219 T256 R258 6.1.1.15 S8G8I1 28867614 AMVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKEGFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIETGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xig A 2.41 BS02 87F A 1 F415 E418 P438 T439 E441 R470 W487 F534 T558 H560 W589 G590 F79 E82 P102 T103 E105 R134 W151 F198 T222 H224 W253 G254 6.1.1.15 S8G8I1 28867614 AMVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKEGFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIETGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xig B 2.41 BS01 ANP B 1 R470 E472 K474 F479 L480 R481 T482 F485 Q555 T558 T592 R594 R131 E133 K135 F140 L141 R142 T143 F146 Q216 T219 T253 R255 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIEGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xig B 2.41 BS02 87F B 1 F415 E418 P438 T439 E441 R470 W487 F534 T558 H560 S588 W589 F76 E79 P99 T100 E102 R131 W148 F195 T219 H221 S249 W250 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAIEGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xig C 2.41 BS01 ANP C 1 R470 E472 F479 L480 R481 T482 F485 Q555 T558 T592 R594 R132 E134 F141 L142 R143 T144 F147 Q217 T220 T254 R256 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKGFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILNTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xig D 2.41 BS02 87F D 1 F415 E418 P438 T439 E441 R470 W487 H491 F534 T558 H560 F77 E80 P100 T101 E103 R132 W149 H153 F196 T220 H222 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKEFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQAGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xih B 2.20 BS02 86U B 1 F415 E418 V419 P438 T439 E441 R470 W487 H491 F534 T558 H560 S588 W589 F77 E80 V81 P100 T101 E103 R132 W149 H153 F196 T220 H222 S250 W251 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKGFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xih C 2.20 BS02 86U C 1 F415 E418 V419 P438 T439 E441 R470 W487 H491 F534 T558 H560 W589 G590 F77 E80 V81 P100 T101 E103 R132 W149 H153 F196 T220 H222 W251 G252 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKGFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xih D 2.20 BS01 ANP D 1 R470 E472 K474 F479 L480 R481 T482 F485 Q555 A556 A557 T558 T592 R594 R132 E134 K136 F141 L142 R143 T144 F147 Q217 A218 A219 T220 T254 R256 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKGFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xii A 2.17 BS01 ANP A 1 R470 E472 R481 T482 F485 Q555 T558 T592 R594 R132 E134 R143 T144 F147 Q217 T220 T254 R256 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKGFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEITGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xii C 2.17 BS02 86X C 1 L405 F415 E418 V419 P438 T439 E441 R470 W487 F534 T558 H560 L73 F77 E80 V81 P100 T101 E103 R132 W149 F196 T220 H222 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKGFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xij B 2.50 BS02 873 B 1 F415 E418 P438 T439 E441 R470 W487 H491 F534 H560 W589 F77 E80 P100 T101 E103 R132 W149 H153 F196 H222 W251 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKGFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQGAMKTLCIPFDQPPMPTKCFYTGKPAKRWTLWGRSY 5xik A 2.50 BS02 87C A 1 S416 E418 T439 E441 R470 W487 F534 H560 W589 G590 S77 E79 T100 E102 R131 W148 F195 H221 W250 G251 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKESPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFNTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xik B 2.50 BS02 87C B 1 S416 E418 T439 E441 R470 W487 H491 F534 T558 H560 S77 E79 T100 E102 R131 W148 H152 F195 T219 H221 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKESPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPIILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xik C 2.50 BS02 87C C 1 S416 P438 T439 E441 R470 W487 H491 F534 H560 W589 S77 P99 T100 E102 R131 W148 H152 F195 H221 W250 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKESPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xik D 2.50 BS02 87C D 1 S416 E418 T439 E441 R470 W487 F534 T558 H560 W589 S77 E79 T100 E102 R131 W147 F194 T218 H220 W249 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKESPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPITGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xil A 1.90 BS01 ZN A 1 C687 C692 C737 C383 C388 C426 6.1.1.5,6.1.1.7 Q4QDS0 28867614 MGIAAKREENFSAWYIDVITKAEMIEYYIIRPWAYYVWKCVQRFLGGKIEKLGVEDCYFPTSETVMYPYYAKWIRSHRDLPVRLNMWNNVIPTPFIRTREFLWQEGHCAWAKAEECAKEVLEILECYASVYEQLLAVPVVRGRKTEKEKFAGGDYTTTVETFIEAVGRGCQGATSHNLGQNFGKMFDIRFQDPENNEQTLIPWQNSWGLSTRVIGVMIMVHGDNRGMVMPPRVASTQVIIIPVGITKDTTEEARQELLASCWRLESELCEGGVRARCDLRDNYSPGWRFNHWEVKGVPLRVELGPRELAERSLAVAVRHSGARHSVAWDAQTPAAVAALLEDVHAQMYARAKETMETHRVRVTEWTEFVPTLNRKCLILAPWCGAMECENQVKKDSAEESKAPSMGAKTLCIPFEQPEEPAEGHECICKGCTKPATTWVLFGRSY 5xil A 1.90 BS02 MG A 1 E468 H662 E164 H358 6.1.1.5,6.1.1.7 Q4QDS0 28867614 MGIAAKREENFSAWYIDVITKAEMIEYYIIRPWAYYVWKCVQRFLGGKIEKLGVEDCYFPTSETVMYPYYAKWIRSHRDLPVRLNMWNNVIPTPFIRTREFLWQEGHCAWAKAEECAKEVLEILECYASVYEQLLAVPVVRGRKTEKEKFAGGDYTTTVETFIEAVGRGCQGATSHNLGQNFGKMFDIRFQDPENNEQTLIPWQNSWGLSTRVIGVMIMVHGDNRGMVMPPRVASTQVIIIPVGITKDTTEEARQELLASCWRLESELCEGGVRARCDLRDNYSPGWRFNHWEVKGVPLRVELGPRELAERSLAVAVRHSGARHSVAWDAQTPAAVAALLEDVHAQMYARAKETMETHRVRVTEWTEFVPTLNRKCLILAPWCGAMECENQVKKDSAEESKAPSMGAKTLCIPFEQPEEPAEGHECICKGCTKPATTWVLFGRSY 5xio A 2.46 BS01 HFG A 1 F307 E310 V311 P330 T331 E333 R362 W379 E381 H383 F426 H452 W481 G482 F78 E81 V82 P101 T102 E104 R133 W150 E152 H154 F197 H223 W252 G253 Q5CWN3 28867614 MGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLETEFSPEVAWVTKSGKSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARLSGAMKSLCIPNDQIFKIEEGKTKCFFCDKLAKKFTLFGRSY 5xio B 2.46 BS02 HFG B 1 F307 E310 V311 P330 T331 E333 R362 W379 H383 F426 T450 H452 W481 G482 F78 E81 V82 P101 T102 E104 R133 W150 H154 F197 T221 H223 W252 G253 Q5CWN3 28867614 MGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLETEFSPEVAWVTKSGKSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARLSGAMKSLCIPNDQIFKIEEGKTKCFFCDKLAKKFTLFGRSY 5xip A 3.10 BS01 ANP A 1 R390 E392 F399 L400 R401 T402 F405 Q475 A476 T478 T512 R514 R131 E133 F140 L141 R142 T143 F146 Q216 A217 T219 T253 R255 U6KWI1 28867614 VTAKKSTNFADWYTQVIVRGELVEYYDISGCYIIRPWAYRIWEAVQKFFDDGIKRLGVENCYFPMFVSQAKLEKEFKPEVAWVTHYGDSELPEKVAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAYTLVLEILELYRQWYEDYLAVPVIKGEKSENEKFAGGKKTTTIEGIIPDTGRGIQAATSHLLGQNFSRMFSIEFEDEKGAKQLVHQTSWGCTTRSLGVMIMTHGDDKGLVLPPRVVAVQAVIIPIIFGMEIVAKCRELERLLNAAGVRVKVDDRTNYTPGWKFNDWELKGVPLRLEIGPRDVESCQTRVVRRDTSEARNVPWAEAASTIPAMLETMQKDLFNKAKAKFEASIEQITTFDEVMPALNRRHVVLAPWCEDPETETQIKRETQRLGAMKPLCIPFDQPPMPEGTRCFFTGRPAKRWCLFGRSY 5xip A 3.10 BS02 HFG A 1 F335 E338 V339 P358 T359 E361 R390 W407 F454 T478 H480 W509 F76 E79 V80 P99 T100 E102 R131 W148 F195 T219 H221 W250 U6KWI1 28867614 VTAKKSTNFADWYTQVIVRGELVEYYDISGCYIIRPWAYRIWEAVQKFFDDGIKRLGVENCYFPMFVSQAKLEKEFKPEVAWVTHYGDSELPEKVAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAYTLVLEILELYRQWYEDYLAVPVIKGEKSENEKFAGGKKTTTIEGIIPDTGRGIQAATSHLLGQNFSRMFSIEFEDEKGAKQLVHQTSWGCTTRSLGVMIMTHGDDKGLVLPPRVVAVQAVIIPIIFGMEIVAKCRELERLLNAAGVRVKVDDRTNYTPGWKFNDWELKGVPLRLEIGPRDVESCQTRVVRRDTSEARNVPWAEAASTIPAMLETMQKDLFNKAKAKFEASIEQITTFDEVMPALNRRHVVLAPWCEDPETETQIKRETQRLGAMKPLCIPFDQPPMPEGTRCFFTGRPAKRWCLFGRSY 5xip B 3.10 BS02 HFG B 1 F335 E338 V339 P358 T359 E361 R390 W407 F454 H480 F76 E79 V80 P99 T100 E102 R131 W148 F195 H221 U6KWI1 28867614 VTAKKSTNFADWYTQVIVRGELVEYYDISGCYIIRPWAYRIWEAVQKFFDDGIKRLGVENCYFPMFVSQAKLEKEFKPEVAWVTHYGDSELPEKVAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAYTLVLEILELYRQWYEDYLAVPVIKGEKSENEKFAGGKKTTTIEGIIPDTGRGIQAATSHLLGQNFSRMFSIEFEDEKGAKQLVHQTSWGCTTRSLGVMIMTHGDDKGLVLPPRVVAVQAVIIPIIFKETGGMEIVAKCRELERLLNAAGVRVKVDDRTNYTPGWKFNDWELKGVPLRLEIGPRDVESCQTRVVRRDTSEARNVPWAEAASTIPAMLETMQKDLFNKAKAKFEASIEQITTFDEVMPALNRRHVVLAPWCEDPETETQIKRETQRLGAMKPLCIPFDQPPMPEGTRCFFTGRPAKRWCLFGRSY 5xip C 3.10 BS01 ANP C 1 R390 F399 R401 T402 F405 Q475 T512 R514 R127 F136 R138 T139 F142 Q212 T249 R251 U6KWI1 28867614 TAKKSTNFADWYTQVIVRGELVEYYDISGCYIIRPWAYRIWEAVQKFFDDGIKRLGVENCYFPMFVSQAKLEKPEVAWVTHYGDSELPEKVAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAYTLVLEILELYRQWYEDYLAVPVIKGEKSENEKFAGGKKTTTIEGIIPDTGRGIQAATSHLLGQNFSRMFSIEFEDEKGAKQLVHQTSWGCTTRSLGVMIMTHGDDKGLVLPPRVVAVQAVIIPIIFMEIVAKCRELERLLNAAGVRVKVDDRTNYTPGWKFNDWELKGVPLRLEIGPRDVESCQTRVVRRDTSEARNVPWAEAASTIPAMLETMQKDLFNKAKAKFEASIEQITTFDEVMPALNRRHVVLAPWCEDPETETQIKRETQRLGAMKPLCIPFDQPPMPEGTRCFFTGRRWCLFGRSY 5xip D 3.10 BS01 ANP D 1 R390 E392 F399 R401 T402 F405 Q475 T512 R514 R127 E129 F136 R138 T139 F142 Q212 T249 R251 U6KWI1 28867614 TAKKSTNFADWYTQVIVRGELVEYYDISGCYIIRPWAYRIWEAVQKFFDDGIKRLGVENCYFPMFVSQAKLEKPEVAWVTHYGDSELPEKVAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAYTLVLEILELYRQWYEDYLAVPVIKGEKSENEKFAGGKKTTTIEGIIPDTGRGIQAATSHLLGQNFSRMFSIEFEDEKGAKQLVHQTSWGCTTRSLGVMIMTHGDDKGLVLPPRVVAVQAVIIPIIFMEIVAKCRELERLLNAAGVRVKVDDRTNYTPGWKFNDWELKGVPLRLEIGPRDVESCQTRVVRRDTSEARNVPWAEAASTIPAMLETMQKDLFNKAKAKFEASIEQITTFDEVMPALNRRHVVLAPWCEDPETETQIKRETQRLGAMKPLCIPFDQPPMCFFTGRWCLFGRSY 5xiq A 2.19 BS02 HFG A 1 L405 F415 E418 V419 P438 T439 E441 R470 W487 E489 H491 F534 T558 H560 W589 G590 L73 F76 E79 V80 P99 T100 E102 R131 W148 E150 H152 F195 T219 H221 W250 G251 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQTGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xiq B 2.19 BS03 MG B 1 E532 K796 E192 K446 6.1.1.15 S8G8I1 28867614 MVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIQATGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGRSY 5xis A 1.78 BS01 XYZ A 1 S134 E138 S25 E29 2.3.2.27 Q8IYW5 29330428 LSKPGELRREYEEEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLSIDINN 5xis D 1.78 BS01 XYZ D 1 R117 E121 R11 E15 2.3.2.27 Q8IYW5 29330428 GHMLSKPGELRREYEEEISKVAAERRASEEEENKASEEYIQRLLAEEEEEEKRQAEKRRRAMEEQLKSDEELARKLSIDINN 5xm0 D 2.87 BS01 NUC I 1 R31 G32 R33 G53 I54 S55 S56 R86 S87 T88 R1 G2 R3 G23 I24 S25 S26 R56 S57 T58 Q9D2U9 RGRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSS 5xm1 A 3.45 BS02 NUC J 1 H39 R40 Y41 P43 G44 T45 V46 A47 R49 R63 K64 L65 R69 D81 R83 H2 R3 Y4 P6 G7 T8 V9 A10 R12 R26 K27 L28 R32 D44 R46 PHRYRPGTVALREIRRYQKATELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER 5xm1 E 3.45 BS02 NUC J 1 H39 R40 Y41 R42 P43 T45 R63 R72 R83 F84 Q85 S86 R116 V117 T118 H2 R3 Y4 R5 P6 T8 R26 R35 R46 F47 Q48 S49 R79 V80 T81 PHRYRPGTVALREIRRYQKATELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA 5ydj B 3.04 BS01 CO B 1 E410 H416 E249 H255 3.1.1.7 Q869C3 DNDPLVVNTDKGRIRGITVDAPSGKKVDVWLGIPYAQPPVGPLRFRHPRPAEKWTGVLNTTTPPNSCVQIVDTVFGDFPGATMWNPNTPLSEDCLYINVVAPRPRPKNAAVMLWIFGGGFYSGTATLDVYDHRALASEENVIVVSLQYRVASLGFLFLGTPEAPGNAGLFDQNLALRWVRDNIHRFGGDPSRVTLFGESAGAVSVSLHLLSALSRDLFQRAILQSGSPTAPWALVSREEATLRALRLAEAVGCPHEPSKLSDAVECLRGKDPHVLVNNEWGTLGICEFPFVPVVDGAFLDETPQRSLASGRFKKTEILTGSNTEEGYYFIIYYLTELLRKEEGVTVTREEFLQAVRELNPYVNGAARQAIVFEYTDWTEPDNPNSNRDALDKMVGDYHFTCNVNEFAQRYAEEGNNVYMYLYTHRSKGNPWPRWTGVMHGDEINYVFGEPLNPTLGYTEDEKDFSRKIMRYWSNFAKTGNPNPNTASSEFPEWPKHTAHGRHYLELGLNTSFVGRGPRLRQCAFWKKYLPQLVAATSN 5ygr A 2.50 BS01 PO4 A 1 T124 D125 G126 N127 H128 D194 G296 T106 D107 G108 N109 H110 D172 G269 4.3.1.15 29294403 QFNTRRKKYGTSLLNGNVGHEVLAFHKKLPNYAVTPLHNLAHLSQRLGLGSIHIKDESWRFGLNAFGLGGSYAVGKYLADKLQCDIALNTPEIKEKIKDCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPLIRAENIRHHGAECTITDLNYDDAVRLAHRMAQTKGWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYEQLAETNSPLPTHLILQAGVGSFAGSVMGYFVEKMQENIPNIIVVEPHQANCLYQSAVMDDGQPHCVTIMAGLACGEPNIISWPIIRDNTSCFISADDCLAAKGMRISAAPRPGTDTPFISGESGAIGVGLLYELMNNMHYQDLANRLQLDASAHVLLISTEGDTSPDIYEDIVWNG 5ygr B 2.50 BS01 PO4 B 1 T124 D125 N127 H128 T101 D102 N104 H105 4.3.1.15 29294403 QFNTRRKKYGTSLLNGNVGHEVLAFHKKLPNYAVTPLHNLAHLSQRLGLGSIHIKDESWRFGLNAFGLGGSYAVGKYLADKLQCDINSKEKIKDCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRAENIRHHGAECTITDLNYDDAVRLAHRMAQTKGWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYEQLAENSPLPTHLILQAGVGSFAGSVMGYFVEKMQENIPNIIVVEPHQANCLYQSAVMIMAGLACGEPNIISWPIIRDNTSCFISADDCLAAKGMRISAAPRPGTDTPFISGESGAIGVGLLYELMNNMHYQDLARLQLDAAHVLLISTEGDTSPDIYEDIVWNGRSA 5ygr C 2.50 BS01 PO4 C 1 T124 D125 G126 N127 H128 D194 T107 D108 G109 N110 H111 D174 4.3.1.15 29294403 YQFNTRRKKYGTSLLNGNVGHEVLAFHKKLPNYAVTPLHNLAHLSQRLGLGSIHIKDESWRFGLNAFGLGGSYAVGKYLADKLQCDINSLSFAIKEKIKDCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKLIRAENIRHHGAECTITDLNYDDAVRLAHRMAQTKGWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYEQLAETNSPLPTHLILQAGVGSFAGSVMGYFVEKMQENIPNIIVVEPHQANCLYQSAVMDDGQPHCVTIMAGLACGEPNIISWPIIRDNTSCFISADDCLAAKGMRISAAPRPGTDTPFISGESGAIGVGLLYELMNNMHYQDLANRLQLDASAHVLLISTEGDTSPDIYEDIVWNGRSA 5ygr C 2.50 BS02 PO4 C 2 H49 N50 T341 H39 N40 T316 4.3.1.15 29294403 YQFNTRRKKYGTSLLNGNVGHEVLAFHKKLPNYAVTPLHNLAHLSQRLGLGSIHIKDESWRFGLNAFGLGGSYAVGKYLADKLQCDINSLSFAIKEKIKDCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKLIRAENIRHHGAECTITDLNYDDAVRLAHRMAQTKGWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYEQLAETNSPLPTHLILQAGVGSFAGSVMGYFVEKMQENIPNIIVVEPHQANCLYQSAVMDDGQPHCVTIMAGLACGEPNIISWPIIRDNTSCFISADDCLAAKGMRISAAPRPGTDTPFISGESGAIGVGLLYELMNNMHYQDLANRLQLDASAHVLLISTEGDTSPDIYEDIVWNGRSA 5ygr D 2.50 BS01 PO4 D 1 T124 D125 N127 H128 G296 T112 D113 N115 H116 G281 4.3.1.15 29294403 QFNTRRKKYGTSLLNGNVGHEVLAFHKKLPNYAVTPLHNLAHLSQRLGLGSIHIKDESWRFGLNAFGLGGSYAVGKYLADKLQCDINSLSFAALNTPEIKEKIKDCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRAENIRHHGAECTITDLNYDDAVRLAHRMAQTKGWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYEQLAETNSPLPTHLILQAGVGSFAGSVMGYFVEKMQENIPNIIVVEPHQANCLYQSAVMDDGQPHCVTATIMAGLACGEPNIISWPIIRDNTSCFISADDCLAAKGMRISAAPRPGTDTPFISGESGAIGVGLLYELMNNHYQDLANRLQLDAAHVLLISTEGDTSPDIYEDIVWNGRSA 5yhi A 2.85 BS01 PO4 A 1 Q115 S118 S200 W201 Q93 S96 S178 W179 P32157 29459651 PMRYPVDVYTGKIQVDGELMLTELGLEGDGPDRALCHYPREHYLYWAREFPEQAELFVAPAFGENLSTDGLTESNVYMGDIFRWGEALIQVSQPRSPCYKLNYHFDISDIAQLMQNTGKVGWLYSVIAPGKVSADAPLELVSRVSDVTVQEAAAIAWHMPFDDDQYHRLLSAAGLSKSWTRTMQKRRLSGKIEDFSRRLWGK 5yzf A 1.77 BS01 HEM A 1 T40 C43 F44 R46 H65 T68 V69 A72 L90 S93 H94 H98 I100 Y104 L105 I108 F139 T40 C43 F44 R46 H65 T68 V69 A72 L90 S93 H94 H98 I100 Y104 L105 I108 F139 P02185 29477977 MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLECFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG 5z25 A 1.70 BS01 HEC A 1 G55 C56 C59 H60 V67 G68 P69 I74 Y78 L85 F88 L89 A95 I96 G55 C56 C59 H60 V67 G68 P69 I74 Y78 L85 F88 L89 A95 I96 O67504 29484831 VDPAKEAIMKPQLTMLKGLSDAELKALADFILRIAKQAQEKQQQDVAKAIFQQKGCGSCHQANVDTVGPSLAKIAQAYAGKEDQLIKFLKGEAPAI 5z2l A 1.70 BS01 NDP A 1 G13 G14 S15 R16 G17 I18 Y37 A38 G39 S40 T58 D59 S60 A61 N82 A83 G84 I85 I105 I130 G131 S132 Y146 K150 P176 G177 P178 I179 T181 A183 N184 G12 G13 S14 R15 G16 I17 Y36 A37 G38 S39 T57 D58 S59 A60 N81 A82 G83 I84 I104 I129 G130 S131 Y145 K149 P175 G176 P177 I178 T180 A182 N183 P39333 29462616 GAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGEALELNADDIDRLFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSLMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGALEH 5za2 A 1.50 BS01 NXL A 1 G63 S64 L119 Q120 Y150 N152 Y222 K314 T315 G316 S317 I345 G56 S57 L112 Q113 Y143 N145 Y215 K307 T308 G309 S310 I338 3.5.2.6 Q9L387 29439972 LTATVDGIIQPMLKAYRIPGMAVAVLKDGKAHYFNYGVANRESGQRVSEQTLFEIGSVSKTLTATLGAYAAVKGGFELDDKVSQHAPWLKGSAFDGVTMAELATYSAGGLPLQFPDEVDSNDKMQTYYRSWSPVYPAGTHRQYSNPSIGLFGHLAANSLGQPFEQLMSQTLLPKLGLHHTYIQVPESAMANYAYGYSKEDKPIRATPGVLAAEAYGIKTGSADLLKFVEANMGYQGDAALKSAIALTHTGFHSVGEMTQGLGWESYDYPVTEQVLLAGNSPAVSFQANPVTRFAVPKAMGEQRLYNKTGSTGGFGAYVAFVPARGIAIVMLANRNYPIEARVKAAHAILSQLAE 6al7 A 1.69 BS01 CA A 1 N137 S138 L147 A148 G149 D175 N110 S111 L120 A121 G122 D148 A0A076NBW8 VVSIPINNAGFEDPFIEVVDDYTVDTPPGWTTYNPNNLVPEKRTTWTSNNGVGYVGPGTQFYNQLAPEGRNIGYIYLAQKPGSGVAGFEQILDATLEPDTKYTLKVDVGNSGGEFQKISLAGFPGYRVELLAGDTVLAADHNNLYIKDGEFKTSTVTFTATPDNPYLDQKLGIRLINLLQGTFSGLDFDNVRLTVEPA 6al8 A 1.64 BS01 CA A 1 D134 F178 T180 D106 F150 T152 A0A076NBW8 VSIPINNAGFEDPFIEVVDDYTVDTPPGWTTYNPNNLVPEKRTTWTSNNGVGYVGPGTQFYNQLAPEGRNIGFIYLAQKPGSGVAGFEQILDATLEPDTKYTLKVDVGNSGGEFQKISLAGFPGYRVELLAGDTVLAADHNNLYIKDGEFKTSTVTFTATPDNPYLDQKLGIRLINLLQGTFSGLDFDNVRLTVEPA 6asc A 2.15 BS03 BU7 A 1 L59 N64 P66 L71 P91 W96 L99 F115 L66 N71 P73 L78 P98 W103 L106 F122 Q9X1X0 IHHHHHHVINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHDWKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEALRKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGIEQGREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIE 6asc B 2.15 BS03 BU7 B 1 N64 P66 L74 P91 H94 W96 L99 F102 V106 F115 N61 P63 L71 P88 H91 W93 L96 F99 V103 F112 Q9X1X0 LKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHDWKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEALRKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGIEQGREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIE 6b21 A 2.45 BS01 C9V A 1 N72 N73 F74 F75 L152 S155 H156 L353 E357 W365 V369 N72 N73 F74 F75 L152 S155 H156 L337 E341 W349 V353 P69681 GASVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTLSYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGKPHNLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLKRPCDVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLADLTVGLRV 6bl8 A 2.50 BS01 PVB A 1 L248 G249 G250 V256 A269 V299 T315 E316 F317 M318 T319 G321 N322 L370 F382 L16 G17 G18 V24 A37 V67 T83 E84 F85 M86 T87 G89 N90 L138 F150 2.7.10.2 P00519 29474075 DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTFTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDPSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSI 6bl8 B 2.50 BS01 PVB B 1 L248 V256 A269 T315 E316 F317 M318 T319 G321 N322 R367 L370 F382 L16 V21 A34 T80 E81 F82 M83 T84 G86 N87 R132 L135 F147 2.7.10.2 P00519 29474075 DKWEMERTDITMKHKLGYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTFTAHGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDPSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISD 6bqb L 1.77 BS01 III P 1 Y32 Y92 T93 A94 Y38 Y98 T99 A100 DIVMTQSPDSLAVSLGERATINCRSSQSVLSSSNNKNYLAWYQHKPRQPPKLLIYWASTRESGVPDRFSGSGSGTDFTLTISSLQAEDVAVYYCQQYYTASPFFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE 6bqb H 1.77 BS01 III P 1 D31 Y32 G33 W52 Y52A V97 G98 I99 D30 Y31 G32 W51 Y52 V100 G101 I102 VQLVESGGGVVQPGRSLRLSCAASGFRFSDYGMHWVRQAPGKGLEWVALIWYDGSNESYLDSVKGRFTISRDNSKNTLYLQMNNLRTEDTAVYYCAKLLVGITTDVFDVWGQGTVVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK 6br5 A 2.04 BS02 GYG A 1 R118 E119 D151 R152 R156 W178 S179 I222 R224 E227 A246 E276 E277 R292 N294 H347 R371 Y406 R36 E37 D69 R70 R74 W96 S97 I140 R142 E145 A164 E194 E195 R210 N212 H265 R289 Y324 3.2.1.18 E0UY46 29453852 EYRNWSKPQCDITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPDKCYQFALGQGTTLNNVHSNNTVRDRTPYRTLLMNELGVPFHLGTKQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYNGRLVDSVVSWSKEILRTQESECVCINGTCTVVMTDGSASGKADTKILFIEEGKIVHTSTLSGSAQHVEECSCYPRYPGVRCVCRDNWKGSNRPIVDINIKDHSIVSSYVCSGLVGDTPRKNDSSSSSHCLDPNNEEGGHGVKGWAFDDGNDVWMGRTISEKSRLGYETFKVIEGWSNPKSKLQINRQVIVDRGNRSGYSGIFSVEGKSCINRCFYVELIRGRKEETEVLWTSNSIVVFCGTSGTYGTGSWPDGADINLMPI 6br6 A 2.04 BS02 E3M A 1 R118 E119 D151 R152 W178 I222 R224 A246 E276 E277 R292 N294 H347 R371 Y406 R36 E37 D69 R70 W96 I140 R142 A164 E194 E195 R210 N212 H265 R289 Y324 3.2.1.18 E0UY46 29453852 EYRNWSKPQCDITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPDKCYQFALGQGTTLNNVHSNNTVRDRTPYRTLLMNELGVPFHLGTKQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYNGRLVDSVVSWSKEILRTQESECVCINGTCTVVMTDGSASGKADTKILFIEEGKIVHTSTLSGSAQHVEECSCYPRYPGVRCVCRDNWKGSNRPIVDINIKDHSIVSSYVCSGLVGDTPRKNDSSSSSHCLDPNNEEGGHGVKGWAFDDGNDVWMGRTISEKSRLGYETFKVIEGWSNPKSKLQINRQVIVDRGNRSGYSGIFSVEGKSCINRCFYVELIRGRKEETEVLWTSNSIVVFCGTSGTYGTGSWPDGADINLMPI 6c0s A 2.35 BS01 EEJ A 1 R39 H40 L41 C42 H57 C58 Y143 L147 I151 D189 A190 C191 K192 G193 D194 S195 T213 S214 W215 G216 G218 C219 G226 V227 Y228 R26 H27 L28 C29 H44 C45 Y134 L137 I141 D182 A183 C184 K185 G186 D187 S188 T206 S207 W208 G209 G211 C212 G219 V220 Y221 3.4.21.27 P03951 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVGYGDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV 6c12 B 2.15 BS01 FAD B 1 G14 A15 G16 G17 A18 S37 K38 V39 S44 H45 T46 S48 A49 Q50 W164 Y165 A166 A201 T202 G203 T213 N214 D221 H354 Y355 G387 E388 G402 S404 L405 L408 G14 A15 G16 G17 A18 S37 K38 V39 S44 H45 T46 S48 A49 Q50 W118 Y119 A120 A155 T156 G157 T167 N168 D175 H308 Y309 G341 E342 G356 S358 L359 L362 1.3.5.1 P0AC43 MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQGGNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMADRTGHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESMTRRSVNMEPKLRPAFPP 6c3a A 1.53 BS01 EGV A 1 T17 E20 A33 H34 S95 F119 N121 N167 K235 R367 T4 E7 A20 H21 S82 F106 N108 N154 K222 R354 29466666 LDLTQHEIQALTMKYNLADAHTHQRQSASQQSIVSRLPQLWYEAEEGLQATYEKRFTEAFFQLHRQPTALVKNKTMLSYAASISTMVAGMFLKKERLAVTLIEPCFDNLYDVLANMDVPLYPIDESVFYDVDRIYPELERRVRTDALFLVDPNNPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASFTLFEPELARFDMYELLENSGVRYLAIEDTGKTWPVQDAKCALITASDDIWETVYNLHTSVLLNVSPFVLNMLTQYVRDSAADRLASVREVLTRNRECARKTLDGSILEYQEPVVKVSVAWFRVDHPELTATDVHRLLSADGVYVLPGRYFYWSEPSKGDAYVRMALAREPEMFADAMALTRQVLDRH 6c3a A 1.53 BS02 EGV B 1 T262 S263 V264 L265 L266 T249 S250 V251 L252 L253 29466666 LDLTQHEIQALTMKYNLADAHTHQRQSASQQSIVSRLPQLWYEAEEGLQATYEKRFTEAFFQLHRQPTALVKNKTMLSYAASISTMVAGMFLKKERLAVTLIEPCFDNLYDVLANMDVPLYPIDESVFYDVDRIYPELERRVRTDALFLVDPNNPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASFTLFEPELARFDMYELLENSGVRYLAIEDTGKTWPVQDAKCALITASDDIWETVYNLHTSVLLNVSPFVLNMLTQYVRDSAADRLASVREVLTRNRECARKTLDGSILEYQEPVVKVSVAWFRVDHPELTATDVHRLLSADGVYVLPGRYFYWSEPSKGDAYVRMALAREPEMFADAMALTRQVLDRH 6c3b A 1.51 BS01 PGE A 1 N86 K87 D251 W254 N60 K61 D225 W228 29466666 KYNLADAHTHQRQSASQQSIVSRLPQLWYEAEEGLQATYEKRFTEAFFQLHRQPTALVKNKTMLSYAASISTMVAGMFLKKERLAVTLIEPCFDNLYDVLANMDVPLYPIDESVFYDVDRIYPELERRVRTDALFLVDPNNPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASFTLFEPELARFDMYELLENSGVRYLAIEDTGKTWPVQDAKCALITASDDIWETVYNLHTSVLLNVSPFVLNMLTQYVRDSAADRLASVREVLTRNRECARKTLDGSILEYQEPVVKVSVAWFRVDHPELTATDVHRLLSADGVYVLPGRYFYWSEPSKGDAYVRMALAREPEMFADAMALTRQVLDR 6c3b A 1.51 BS02 PGE A 2 E66 T88 M89 L90 H261 N267 E40 T62 M63 L64 H235 N241 29466666 KYNLADAHTHQRQSASQQSIVSRLPQLWYEAEEGLQATYEKRFTEAFFQLHRQPTALVKNKTMLSYAASISTMVAGMFLKKERLAVTLIEPCFDNLYDVLANMDVPLYPIDESVFYDVDRIYPELERRVRTDALFLVDPNNPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASFTLFEPELARFDMYELLENSGVRYLAIEDTGKTWPVQDAKCALITASDDIWETVYNLHTSVLLNVSPFVLNMLTQYVRDSAADRLASVREVLTRNRECARKTLDGSILEYQEPVVKVSVAWFRVDHPELTATDVHRLLSADGVYVLPGRYFYWSEPSKGDAYVRMALAREPEMFADAMALTRQVLDR 6c3b B 1.51 BS01 PGE B 1 Y142 R175 E315 V317 Y116 R149 E289 V291 29466666 KYNLADAHTHQRQSASQQSIVSRLPQLWYEAEEGLQATYEKRFTEAFFQLHRQPTALVKNKTMLSYAASISTMVAGMFLKKERLAVTLIEPCFDNLYDVLANMDVPLYPIDESVFYDVDRIYPELERRVRTDALFLVDPNNPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASFTLFEPELARFDMYELLENSGVRYLAIEDTGKTWPVQDAKCALITASDDIWETVYNLHTSVLLNVSPFVLNMLTQYVRDSAADRLASVREVLTRNRECARKTLDGSILEYQEPVVKVSVAWFRVDHPELTATDVHRLLSADGVYVLPGRYFYWSEPSKGDAYVRMALAREPEMFADAMALTRQVLDR 6c3c A 1.50 BS01 EJ1 A 1 D32 A33 A93 A94 S95 F119 N121 N167 D198 C200 K235 K243 R367 D7 A8 A68 A69 S70 F94 N96 N142 D173 C175 K210 K218 R342 29466666 MKYNLADAHTHQRQSASQQSIVSRLPQLWYEAEEGLQATYEKRFTEAFFQLHRQPTALVKNKTMLSYAASISTMVAGMFLKKERLAVTLIEPCFDNLYDVLANMDVPLYPIDESVFYDVDRIYPELERRVRTDALFLVDPNNPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASFTLFEPELARFDMYELLENSGVRYLAIEDTGKTWPVQDAKCALITASDDIWETVYNLHTSVLLNVSPFVLNMLTQYVRDSAADRLASVREVLTRNRECARKTLDGSILEYQEPVVKVSVAWFRVDHPELTATDVHRLLSADGVYVLPGRYFYWSEPSKGDAYVRMALAREPEMFADAMALTRQVLDR 6c3c A 1.50 BS02 EJ1 B 1 T262 L265 T237 L240 29466666 MKYNLADAHTHQRQSASQQSIVSRLPQLWYEAEEGLQATYEKRFTEAFFQLHRQPTALVKNKTMLSYAASISTMVAGMFLKKERLAVTLIEPCFDNLYDVLANMDVPLYPIDESVFYDVDRIYPELERRVRTDALFLVDPNNPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASFTLFEPELARFDMYELLENSGVRYLAIEDTGKTWPVQDAKCALITASDDIWETVYNLHTSVLLNVSPFVLNMLTQYVRDSAADRLASVREVLTRNRECARKTLDGSILEYQEPVVKVSVAWFRVDHPELTATDVHRLLSADGVYVLPGRYFYWSEPSKGDAYVRMALAREPEMFADAMALTRQVLDR 6c3c B 1.50 BS01 EJ1 A 1 T262 L265 L266 T237 L240 L241 29466666 MKYNLADAHTHQRQSASQQSIVSRLPQLWYEAEEGLQATYEKRFTEAFFQLHRQPTALVKNKTMLSYAASISTMVAGMFLKKERLAVTLIEPCFDNLYDVLANMDVPLYPIDESVFYDVDRIYPELERRVRTDALFLVDPNNPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASFTLFEPELARFDMYELLENSGVRYLAIEDTGKTWPVQDAKCALITASDDIWETVYNLHTSVLLNVSPFVLNMLTQYVRDSAADRLASVREVLTRNRECARKTLDGSILEYQEPVVKVSVAWFRVDHPELTATDVHRLLSADGVYVLPGRYFYWSEPSKGDAYVRMALAREPEMFADAMALTRQVLDRH 6c3d A 1.55 BS01 EMS A 1 T17 E20 A33 H34 A93 A94 S95 F119 N121 V163 N167 D198 C200 K235 K243 R367 T4 E7 A20 H21 A80 A81 S82 F106 N108 V150 N154 D185 C187 K222 K230 R354 29466666 LDLTQHEIQALTMKYNLADAHTHQRQSASQQSIVSRLPQLWYEAEEGLQATYEKRFTEAFFQLHRQPTALVKNKTMLSYAASISTMVAGMFLKKERLAVTLIEPCFDNLYDVLANMDVPLYPIDESVFYDVDRIYPELERRVRTDALFLVDPNNPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASFTLFEPELARFDMYELLENSGVRYLAIEDTGKTWPVQDAKCALITASDDIWETVYNLHTSVLLNVSPFVLNMLTQYVRDSAADRLASVREVLTRNRECARKTLDGSILEYQEPVVKVSVAWFRVDHPELTATDVHRLLSADGVYVLPGRYFYWSEPSKGDAYVRMALAREPEMFADAMALTRQVLDR 6c3d A 1.55 BS02 EMS B 1 T262 S263 L265 L266 T249 S250 L252 L253 29466666 LDLTQHEIQALTMKYNLADAHTHQRQSASQQSIVSRLPQLWYEAEEGLQATYEKRFTEAFFQLHRQPTALVKNKTMLSYAASISTMVAGMFLKKERLAVTLIEPCFDNLYDVLANMDVPLYPIDESVFYDVDRIYPELERRVRTDALFLVDPNNPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASFTLFEPELARFDMYELLENSGVRYLAIEDTGKTWPVQDAKCALITASDDIWETVYNLHTSVLLNVSPFVLNMLTQYVRDSAADRLASVREVLTRNRECARKTLDGSILEYQEPVVKVSVAWFRVDHPELTATDVHRLLSADGVYVLPGRYFYWSEPSKGDAYVRMALAREPEMFADAMALTRQVLDR 6c9x A 1.46 BS01 VOG A 1 D73 W169 D197 I198 W271 W305 D307 M308 R404 W417 D420 F453 H478 D76 W172 D200 I201 W274 W308 D310 M311 R407 W420 D423 F456 H481 3.2.1.- A5ZY13 SNAMIRKYRYGAPFDTEALTEKIETAEEAFPYGEISQKEGFAFTYIMDEDDIVYGLGESNRGINKRGYCYISNCTDDPIHTEDKRSLYGAHNFIIVSGKTTFGLFFDYPSKLTFDIGYTRMDTLKVSCENADLDIYVIEGENAYDIVKQFRRVIGRSYIPPKFAFGFGQSRWGYTTKEDFRAVAKGYRENHIPIDMIYMDIDYMQDFKDFTVNEKNFPDFPEFVKEMKDQELRLIPIIDAGVKVEKGYEVYEEGVKNNYFCKREDGSDFVAAVWPGDTHFPDMLNPEARKWFGDKYRFLIDQGIEGFWNDMNEPAIFYSSEGLAEAKEFAGEFAKDTEGKIHPWAMQAKMKDIVNSPEDYKRFYHNVNGKKIRHDKVHNLFGYNMTRAAGEAFERIDPEKRFLMFSRSSYIGMHRYGGIWMGDNKSWWSHILLNLKMLPSLNMCGFMYTGADLGGFGDDTTRDLLLRFLALGVFTPLMRDHAAEGTREQECYQFENIEDFRSVINARYRLVPYLYSEYMKAALNDDMYFKPLGFVYPDDKMAIRVEDQLMLGNEIMIAPVYEQNARGRYVYLPEEMKFIKFMPDGSISEEVLEKGVHYVDVALNEVPLFIRSGKCIPVAEAAECVKDIDTENMQLIGYEGSSYTLYEDDGIHKDYDKKENYRVLTK 6cau A 2.50 BS01 ANP A 1 T130 H131 G132 K133 T134 T135 E177 N197 H295 N299 T115 H116 G117 K118 T119 T120 E162 N182 H274 N278 6.3.2.8 B7GV74 HHHMRRIKHIHFVGIGGAGMCGIAEVLANQGYKISGSDIKASKTTQQLEENGIKVYIGHEAENIKNANVLVVSTAIDPENPEVKAAIEQRIPIVRRAEMLGELMRYRHGIAVAGTHGKTTTTSLLTTMLAEENLDPTYVIGGLLNSTGVNAALGESRFIVAEADESDASFLYLQPMAAIVTNIDADGSFDKLKDTFVQFLHNLPFYGLAVVCGDDANIREILPRVGRPVITYGFNEDNDIRAIDVEQDGMRSHFTVLRKGREPLRLTINQPGLHNVLNALAAIGVATDEGVSDEAISRALKGFSGVG 6cau A 2.50 BS02 MG A 1 T134 E177 T119 E162 6.3.2.8 B7GV74 HHHMRRIKHIHFVGIGGAGMCGIAEVLANQGYKISGSDIKASKTTQQLEENGIKVYIGHEAENIKNANVLVVSTAIDPENPEVKAAIEQRIPIVRRAEMLGELMRYRHGIAVAGTHGKTTTTSLLTTMLAEENLDPTYVIGGLLNSTGVNAALGESRFIVAEADESDASFLYLQPMAAIVTNIDADGSFDKLKDTFVQFLHNLPFYGLAVVCGDDANIREILPRVGRPVITYGFNEDNDIRAIDVEQDGMRSHFTVLRKGREPLRLTINQPGLHNVLNALAAIGVATDEGVSDEAISRALKGFSGVG 6cbk A 1.75 BS01 PMP A 1 S103 G104 T105 Y129 H130 G131 S176 D204 V206 K231 S98 G99 T100 Y124 H125 G126 S171 D199 V201 K226 2.6.1.93,2.6.1.95 Q53U08 SLLAEFPTCPRDEKDRPRVFTAASGAWLTDESGFRWIDFDNARGSILLGHGDPVVAEAVARAATGADGTATGWSRRVDAVLERLHALCGGEVVGLFRSGTAAVRAAVLAVREATGRPLLLSAGYHGYDPMWYPSEAPLEPNADGVVDFFFDLGLLRELLRAPERVAAVVVSPDHMHLSPGWYRELRRLCSAAGVVLVADEVKVGLRYAPGLSTAELLAPDVWVVAKGMANGHAVSAVGGSRRLLKPLKEVSFTSFFEPTILAAADAALARVATGEPQRAVREAGDRFLRHARKALDDASLPVEIAGDGTFFQFVPATEELEEALYGAANAEGLLFYAGDNQGVSAAFDEAVLGEAERRFARVCERLAPYAGGEPVGDAARYRVAWNVMDGLRQAPRDREETTGLLARLL 6cbk B 1.75 BS02 PMP B 1 G104 T105 Y129 H130 G131 S176 D204 V206 K207 K231 H424 G99 T100 Y124 H125 G126 S171 D199 V201 K202 K226 H419 2.6.1.93,2.6.1.95 Q53U08 SLLAEFPTCPRDEKDRPRVFTAASGAWLTDESGFRWIDFDNARGSILLGHGDPVVAEAVARAATGADGTATGWSRRVDAVLERLHALCGGEVVGLFRSGTAAVRAAVLAVREATGRPLLLSAGYHGYDPMWYPSEAPLEPNADGVVDFFFDLGLLRELLRAPERVAAVVVSPDHMHLSPGWYRELRRLCSAAGVVLVADEVKVGLRYAPGLSTAELLAPDVWVVAKGMANGHAVSAVGGSRRLLKPLKEVSFTSFFEPTILAAADAALARVATGEPQRAVREAGDRFLRHARKALDDASLPVEIAGDGTFFQFVPATEELEEALYGAANAEGLLFYAGDNQGVSAAFDEAVLGEAERRFARVCERLAPYAGGEPVGDAARYRVAWNVMDGLRQAPRDREETTGLLARLLDDLEHHHHHH 6ccf A 2.10 BS01 H1N A 1 I134 G135 V142 A155 K157 V212 F230 D231 L232 L233 R234 G236 N280 L282 D293 I12 G13 V20 A33 K35 V61 F79 D80 L81 L82 R83 G85 N129 L131 D142 2.7.11.17 Q8N5S9 MQLNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTK 6ccf B 2.10 BS01 H1N B 1 I134 G135 V142 A155 K157 F230 D231 L232 L233 R234 K235 G236 N280 L282 A292 D293 I12 G13 V20 A33 K35 F81 D82 L83 L84 R85 K86 G87 N131 L133 A143 D144 2.7.11.17 Q8N5S9 MQLNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTK 6cct A 2.40 BS01 III B 1 Q132 L159 I161 E237 G251 A252 S253 Y258 Y273 S278 Q282 Q9 L36 I38 E114 G125 A126 S127 Y132 Y147 S152 Q156 Q8IVV7 SGSKFRGHQKSKGNSYDVEVVLQHVDTGNSYLCGYLKIKGLTEEYPTLTTFFEGEIISKKHPFLTRKWDADEDVDRKHWGKFLAFYQYAKSFNSDDFDYEELKNGDYVFMRWKEQFLVPDHTISGASFAGFYYICFQKSAASIEGYYYHRSSEWYQSLNLTHV 6ccu A 1.75 BS01 III B 1 Q132 L159 I161 L164 E237 G251 A252 S253 Y258 Y273 H275 S278 Q8 L35 I37 L40 E112 G126 A127 S128 Y133 Y148 H150 S153 Q8IVV7 GSKFRGHQKSKGNSYDVEVVLQHVDTGNSYLCGYLKIKGLTEEYPTLTTFFEGEIISKKHPFLTRKWDADEDVDRKHWGKFLAFYQYASFNSDDFDYEELKNGDYVFMRWKEQFLVPDHTIKDISGASFAGFYYICFQKSAASIEGYYYHRSSEWYQSLNLTHV 6cd6 A 2.20 BS01 DXV A 1 I134 K136 G137 V142 A155 K157 F230 D231 L232 L233 G236 P237 N280 L282 D293 I10 K12 G13 V18 A31 K33 F85 D86 L87 L88 G91 P92 N135 L137 D148 2.7.11.17 Q8N5S9 LNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTK 6cd6 B 2.20 BS01 DXV B 1 I134 G135 K136 G137 V142 A155 K157 F230 D231 L232 L233 G236 P237 N280 L282 D293 I12 G13 K14 G15 V20 A33 K35 F86 D87 L88 L89 G92 P93 N136 L138 D149 2.7.11.17 Q8N5S9 MQLNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTK 6cd6 C 2.20 BS01 DXV C 1 I134 G137 V142 A155 K157 F230 D231 L232 L233 G236 P237 N280 L282 D293 I11 G14 V19 A32 K34 F85 D86 L87 L88 G91 P92 N135 L137 D148 2.7.11.17 Q8N5S9 QLNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTK 6cd8 A 1.60 BS01 III C 1 Q132 Y139 I161 L164 E237 G251 A252 S253 Y258 Y273 S278 Q282 Q10 Y17 I39 L42 E115 G129 A130 S131 Y136 Y151 S156 Q160 Q8IVV7 GSGSKFRGHQKSKGNSYDVEVVLQHVDTGNSYLCGYLKIKGLTEEYPTLTTFFEGEIISKKHPFLTRKWDADEDVDRKHWGKFLAFYQYAKSFNSDDFDYEELKNGDYVFMRWKEQFLVPDHTIKDISGASFAGFYYICFQKSAASIEGYYYHRSSEWYQSLNLTHV 6cd8 B 1.60 BS01 III D 1 Q132 Y139 L164 E237 G251 A252 S253 Y258 Y273 Q282 Q8 Y15 L40 E113 G127 A128 S129 Y134 Y149 Q158 Q8IVV7 GSKFRGHQKSKGNSYDVEVVLQHVDTGNSYLCGYLKIKGLTEEYPTLTTFFEGEIISKKHPFLTRKWDADEDVDRKHWGKFLAFYQYAKSFNSDDFDYEELKNGDYVFMRWKEQFLVPDHTIKDISGASFAGFYYICFQKSAASIEGYYYHRSSEWYQSLNLTHV 6cd9 A 1.55 BS01 III B 1 Q132 N137 Y139 I161 G163 L164 E237 G251 A252 S253 Y258 Y273 H275 S277 S278 Q282 Q9 N14 Y16 I38 G40 L41 E114 G128 A129 S130 Y135 Y150 H152 S154 S155 Q159 Q8IVV7 SGSKFRGHQKSKGNSYDVEVVLQHVDTGNSYLCGYLKIKGLTEEYPTLTTFFEGEIISKKHPFLTRKWDADEDVDRKHWGKFLAFYQYAKSFNSDDFDYEELKNGDYVFMRWKEQFLVPDHTIKDISGASFAGFYYICFQKSAASIEGYYYHRSSEWYQSLNLTHV 6cdc A 1.75 BS01 III C 1 Q132 S134 K135 I161 L164 E237 G251 A252 S253 Y258 Y273 H275 S277 S278 E279 Q282 Q9 S11 K12 I38 L41 E111 G125 A126 S127 Y132 Y147 H149 S151 S152 E153 Q156 Q8IVV7 SGSKFRGHQKSKGNSYDVEVVLQHVDTGNSYLCGYLKIKGLTEEYPTLTTFFEGEIISKKHPFLTRKWDADEDVDRKHWGKFLAFYQYFNSDDFDYEELKNGDYVFMRWKEQFLVPDHTIKDISGASFAGFYYICFQKSAASIEGYYYHRSSEWYQSLNLTHV 6cdg A 1.60 BS01 III B 1 Q132 S134 L164 E237 I249 G251 A252 S253 Y258 Y273 R276 S277 S278 E279 Q282 Q9 S11 L41 E112 I124 G126 A127 S128 Y133 Y148 R151 S152 S153 E154 Q157 Q8IVV7 SGSKFRGHQKSKGNSYDVEVVLQHVDTGNSYLCGYLKIKGLTEEYPTLTTFFEGEIISKKHPFLTRKWDADEDVDRKHWGKFLAFYQYAKNSDDFDYEELKNGDYVFMRWKEQFLVPDHTIKDISGASFAGFYYICFQKSAASIEGYYYHRSSEWYQSLNLTHV 6cfm A 2.45 BS01 EA7 A 1 I43 V69 K71 E83 Y87 P111 M131 D132 R133 F134 G135 D137 L184 V196 D197 I23 V44 K46 E58 Y62 P86 M106 D107 R108 F109 G110 D112 L159 V171 D172 2.7.11.1 Q99986 EQFAVGEIITDMAAAAWKVGLPIGCIYLADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKAYAADPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPAANAPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDL 6cfm B 2.45 BS01 EA7 B 1 I51 K71 E83 M131 D132 F134 G135 L184 V196 D197 I22 K37 E45 M87 D88 F90 G91 L140 V152 D153 2.7.11.1 Q99986 FAVGEIITDMAAAAWKVGLPCIYLADMNGSDAPCVVKVEPPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKAYAADPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPAANAPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDL 6cfm D 2.45 BS01 EA7 D 1 V69 K71 E83 M131 D132 R133 F134 G135 L184 V196 D197 V41 K43 E55 M103 D104 R105 F106 G107 L156 V168 D169 2.7.11.1 Q99986 QFAVGEIITDMAAAAWKVGLPIGCIYLADMNESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKAYAADPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPAANAPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDL 6chd A 2.50 BS01 KAA A 1 G277 A299 E301 R323 E325 T330 H331 N332 F335 T337 E339 Y341 E494 I495 N497 Y499 E501 G546 W547 G548 G550 R553 I564 G207 A229 E231 R253 E255 T260 H261 N262 F265 T267 E269 Y271 E424 I425 N427 Y429 E431 G476 W477 G478 G480 R483 I494 2.7.7.-,6.1.1.6 Q15046 VDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPE 6ci6 A 2.80 BS01 NBO A 1 N390 C391 F402 R409 Y410 K413 L429 V432 G433 C437 S448 L452 S488 N388 C389 F400 R407 Y408 K411 L427 V430 G431 C435 S446 L450 S486 P35747 HKSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGREDKEACFAEEGPKLVASSQLALA 6ci6 A 2.80 BS02 NBO A 2 D401 N404 A405 K540 E541 K544 L547 D399 N402 A403 K538 E539 K542 L545 P35747 HKSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGREDKEACFAEEGPKLVASSQLALA 6ci6 A 2.80 BS03 KNA A 1 A212 L326 K350 L480 A481 A210 L324 K348 L478 A479 P35747 HKSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGREDKEACFAEEGPKLVASSQLALA 6cia A 2.30 BS01 NDP A 1 G20 T21 W22 D50 Y55 H113 S142 N143 Q165 Y193 C194 P195 L196 A197 Q198 A199 R201 A224 I240 P241 K242 A243 A244 S245 H248 Q251 N252 G20 T21 W22 D50 Y55 H113 S142 N143 Q165 Y193 C194 P195 L196 A197 Q198 A199 R201 A224 I240 P241 K242 A243 A244 S245 H248 Q251 N252 1.1.1.- W9BFN4 MVKKTVRFGEQAAVPAIGLGTWYMGEHAAQRQQEVAALRAGIDHGLTVIDTAEMYADGGAEEVVGQAIRGLRDRVVLVSKVYPWHAGKAAMHRACENSLRRLQTDYLDMYLLHWRGDIPLQETVEAMEKLVAEGKIRRWGVSNLDTEDMQALWRTADGEHCATNQVLYHLASRGIEYDLLPWCQQHSLPVMAYCPLAQAGRLRDGLFQHSDIINMANARGITVAQLLLAWVIRHPGVLAIPKAASIEHVVQNAAALDIVLSGEELAQLDRLYPPPQRKTRLDMV 6cig A 1.65 BS01 T3A A 1 G149 F150 W151 D152 D239 F241 R266 G146 F147 W148 D149 D236 F238 R263 2.1.1.150 O24529 11224575 SINGRKPSEIFKAQALLYKHIYAFIDSMSLKWAVEMNIPNIIQNHGKPISLSNLVSILQVPSSKIGNVRRLMRYLAHNGFFEIITKEEESYALTVASELLVRGSDLCLAPMVECVLDPTLSGSYHELKKWIYEEDLTLFGVTLGSGFWDFLDKNPEYNTSFNDAMASDSKLINLALRDCDFVFDGLESIVDVGGGTGTTAKIICETFPKLKCIVFDRPQVVENLSGSNNLTYVGGDMFTSIPNADAVLLKYILHNWTDKDCLRILKKCKEAVTNDGKRGKVTIIDMVIDKKKDENQVTQIKLLMDVNMACLNGKERNEEEWKKLFIEAGFQHYKISPLTGFLSLIEIYP 6cig A 1.65 BS02 SAH A 1 W151 F164 M168 G196 D219 R220 D239 M240 F241 K253 Y254 I255 W148 F161 M165 G193 D216 R217 D236 M237 F238 K250 Y251 I252 2.1.1.150 O24529 11224575 SINGRKPSEIFKAQALLYKHIYAFIDSMSLKWAVEMNIPNIIQNHGKPISLSNLVSILQVPSSKIGNVRRLMRYLAHNGFFEIITKEEESYALTVASELLVRGSDLCLAPMVECVLDPTLSGSYHELKKWIYEEDLTLFGVTLGSGFWDFLDKNPEYNTSFNDAMASDSKLINLALRDCDFVFDGLESIVDVGGGTGTTAKIICETFPKLKCIVFDRPQVVENLSGSNNLTYVGGDMFTSIPNADAVLLKYILHNWTDKDCLRILKKCKEAVTNDGKRGKVTIIDMVIDKKKDENQVTQIKLLMDVNMACLNGKERNEEEWKKLFIEAGFQHYKISPLTGFLSLIEIYP 6ck7 A 1.65 BS01 ZN A 1 Q51 C91 H133 H137 Q53 C93 H135 H139 3.5.1.88 A0A128NM93 HHMAIRKILYLPDERLRKIAKPVETFDESLQTLINDMFDTMYDARGVGLAAPQIGVSLRLSVIDIVGDKKEQIVIVNPEIVSSHGEKEFEEGCLSVPGAYDTVVRAEKVTVKALDRFGKPFEITGEGLLAECLQHEIDHMNGKLFVDMLSPLKRMMARRKLDKFKRLQARKP 6ck7 A 1.65 BS02 BB2 A 1 G44 V45 G46 Q51 E88 G90 C91 L92 E129 C130 H133 E134 H137 G46 V47 G48 Q53 E90 G92 C93 L94 E131 C132 H135 E136 H139 3.5.1.88 A0A128NM93 HHMAIRKILYLPDERLRKIAKPVETFDESLQTLINDMFDTMYDARGVGLAAPQIGVSLRLSVIDIVGDKKEQIVIVNPEIVSSHGEKEFEEGCLSVPGAYDTVVRAEKVTVKALDRFGKPFEITGEGLLAECLQHEIDHMNGKLFVDMLSPLKRMMARRKLDKFKRLQARKP 6ck7 C 1.65 BS03 BB2 D 1 E88 Y98 E90 Y100 3.5.1.88 A0A128NM93 HHMAIRKILYLPDERLRKIAKPVETFDESLQTLINDMFDTMYDARGVGLAAPQIGVSLRLSVIDIVGDKKEQIVIVNPEIVSSHGEKEFEEGCLSVPGAYDTVVRAEKVTVKALDRFGKPFEITGEGLLAECLQHEIDHMNGKLFVDMLSPLKRMMARRKLDKFKRLQARKP 6ei1 A 1.73 BS01 AYE A 1 G357 W358 C360 W423 G490 H491 G118 W119 C121 W184 G247 H248 Q96AP4 29476094 LQQEEDRKRRSEESRQEIEEFQKLQRQYGLDNSGGYKQQQLRNMEIEVNRGRMPPSEFHRRKADMMESLALGFDDGKTKTSGIIEALHRYYQNAATDVRRVWLSSVVDHFHSSLGDKGWGCGYRNFQMLLSSLLQNDAYNDCLKGMLIPCIPKIQSMIEDAWKEGFDPQGASQLNNRLQGTKAWIGACEVYILLTSLRVKCHIVDFHKSTGPLGTHPRLFEWILNYYSSSPKVVCTSKPPIYLQHQGHSRTVIGIEEKKNRTLCLLILDPGCPSREMQKLLKQDIEASSLKQLRKSMGNLKHKQYQILAVEGALSLEEKLARRQASQVFTAEKIP 6elh A 4.50 BS01 CA A 1 G76 Y78 E411 Y412 G75 Y77 E410 Y411 C6S880 29483528 GQYKKLWYLLFAVLAVCFTILGYMGSEVYKKAPPYPEQVVSASGKVLMAKDDILAGQSAWQTTGGMEVGSVLGHGAYQAPDWTADWLHRELSAWLDLTAQQTYGKKFDEVSPEEQAVLKTRLADEYRNQSRIKEDGSVVISDTRVKAIESILPYYHGVYGDDPALQTTREHFAMKNNTLPSQEAREKLFDFFFWTSWSASTNRPDETFTYTNNWPHEPLINNVPTTENYMWSFTSVVLLLMGIGLLMWGYSFLTKHEEVEVPTEDPISKVQLTPSQKALGKYVFLTVALFVVQVLLGGLTAHYTVEGQGFYGIDEALGFEMSDWFPYALTRTWHIQSAIFWIATGFLTAGLFLAPIVNGGKDPKFQRAGVNFLYIALFIVVGGSYAGNFFALTHILPPEFNFWFGHQGYEYLDLGRFWQLLLMVGLLLWLFLMLRCTVSAFKEKGVDKNLLAIFVASMVGVGVFYAPGLFYGEKSPIAVMEYWRWWVVHLWVEGFFEVFATAAFAFVFYNMGFVRRSTATASTLAAAAIFMLGGVPGTLHHLYFSGSTSASMAIGACFSALEVVPLVLLGREAYEHWSYQHLSEWAKRLRWPLMCFVAVAFWNMIGAGVFGFLINPPISLFYIQGLNTSAVHAHAALFGVYGFLALGFVLLVARYLKPNVQFDDKLMTWGFWLLNGGLVGMIAISLLPVGVIQAYASITHGLWYARSEEFLQMEILDTLRWVRTAADLIFIGGAICVAIQATKIVFGRD 6elh A 4.50 BS02 HEM A 1 Y78 E411 Y412 W486 H490 E494 H541 H542 S560 E563 A608 G612 I615 L621 Q625 S630 H633 A634 A637 Y642 Y77 E410 Y411 W485 H489 E493 H540 H541 S559 E562 A607 G611 I614 L620 Q624 S629 H632 A633 A636 Y641 C6S880 29483528 GQYKKLWYLLFAVLAVCFTILGYMGSEVYKKAPPYPEQVVSASGKVLMAKDDILAGQSAWQTTGGMEVGSVLGHGAYQAPDWTADWLHRELSAWLDLTAQQTYGKKFDEVSPEEQAVLKTRLADEYRNQSRIKEDGSVVISDTRVKAIESILPYYHGVYGDDPALQTTREHFAMKNNTLPSQEAREKLFDFFFWTSWSASTNRPDETFTYTNNWPHEPLINNVPTTENYMWSFTSVVLLLMGIGLLMWGYSFLTKHEEVEVPTEDPISKVQLTPSQKALGKYVFLTVALFVVQVLLGGLTAHYTVEGQGFYGIDEALGFEMSDWFPYALTRTWHIQSAIFWIATGFLTAGLFLAPIVNGGKDPKFQRAGVNFLYIALFIVVGGSYAGNFFALTHILPPEFNFWFGHQGYEYLDLGRFWQLLLMVGLLLWLFLMLRCTVSAFKEKGVDKNLLAIFVASMVGVGVFYAPGLFYGEKSPIAVMEYWRWWVVHLWVEGFFEVFATAAFAFVFYNMGFVRRSTATASTLAAAAIFMLGGVPGTLHHLYFSGSTSASMAIGACFSALEVVPLVLLGREAYEHWSYQHLSEWAKRLRWPLMCFVAVAFWNMIGAGVFGFLINPPISLFYIQGLNTSAVHAHAALFGVYGFLALGFVLLVARYLKPNVQFDDKLMTWGFWLLNGGLVGMIAISLLPVGVIQAYASITHGLWYARSEEFLQMEILDTLRWVRTAADLIFIGGAICVAIQATKIVFGRD 6elh A 4.50 BS03 HEM A 2 Y78 F291 Q294 V295 G298 G299 T301 A302 R332 H335 I336 E411 A634 H635 L638 F639 M682 R721 R724 D728 F731 I732 Y77 F290 Q293 V294 G297 G298 T300 A301 R331 H334 I335 E410 A633 H634 L637 F638 M681 R720 R723 D727 F730 I731 C6S880 29483528 GQYKKLWYLLFAVLAVCFTILGYMGSEVYKKAPPYPEQVVSASGKVLMAKDDILAGQSAWQTTGGMEVGSVLGHGAYQAPDWTADWLHRELSAWLDLTAQQTYGKKFDEVSPEEQAVLKTRLADEYRNQSRIKEDGSVVISDTRVKAIESILPYYHGVYGDDPALQTTREHFAMKNNTLPSQEAREKLFDFFFWTSWSASTNRPDETFTYTNNWPHEPLINNVPTTENYMWSFTSVVLLLMGIGLLMWGYSFLTKHEEVEVPTEDPISKVQLTPSQKALGKYVFLTVALFVVQVLLGGLTAHYTVEGQGFYGIDEALGFEMSDWFPYALTRTWHIQSAIFWIATGFLTAGLFLAPIVNGGKDPKFQRAGVNFLYIALFIVVGGSYAGNFFALTHILPPEFNFWFGHQGYEYLDLGRFWQLLLMVGLLLWLFLMLRCTVSAFKEKGVDKNLLAIFVASMVGVGVFYAPGLFYGEKSPIAVMEYWRWWVVHLWVEGFFEVFATAAFAFVFYNMGFVRRSTATASTLAAAAIFMLGGVPGTLHHLYFSGSTSASMAIGACFSALEVVPLVLLGREAYEHWSYQHLSEWAKRLRWPLMCFVAVAFWNMIGAGVFGFLINPPISLFYIQGLNTSAVHAHAALFGVYGFLALGFVLLVARYLKPNVQFDDKLMTWGFWLLNGGLVGMIAISLLPVGVIQAYASITHGLWYARSEEFLQMEILDTLRWVRTAADLIFIGGAICVAIQATKIVFGRD 6en6 A 1.80 BS01 FUC A 1 D417 T418 D412 T413 3.2.1.-,3.4.15.1 P12821 29206036 LDPGLQPGQFSADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLPCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMVGLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEG 6en6 A 1.80 BS02 FUC A 2 T478 H483 T473 H478 3.2.1.-,3.4.15.1 P12821 29206036 LDPGLQPGQFSADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLPCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMVGLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEG 6eom A 2.10 BS01 ZN A 1 H379 H383 E412 H348 H352 E381 H1XW48 29420664 LKRMIAQFAPTEIKYDHSLLDERKQKVVENLYRAAKIMDEIFLDQVYSKNFEIREQLRASSDPLDQLRLEYFTIMFGPFDRLNHDKPFIGNTPKPKGANFYPPDMTREEFENWLKAHPEDEAAFTSEFTVIRRQDGKLVAIPYSEYYKEYLTRAADYLKKAAEFADNPSLKKYLQLRAEAFLNNDYYESDLAWMDLNDHTIEVVIGPYEVYEDKLFNYKAAFEAFITLRDPVESAKLKKFVGYLDEMEKNLPIPDAYKNFNRGSESPMVVVQEVFSAGDTKAGVQTLAFNLPNDERVREAKGSKKVMLKNIHEAKFDKLLKPIAEKVLFAEQLPLVTFEGFFNHTLMHEISHGLGPGKIVLNGRQTEVKKELKETYSSIEECKADVLGMYNNLFMIEKGVYPPEFEKQIYVTFLAGIFRTIRFGINEAHGAGNAVIFNYLLEKGAYQFDPAAHRVKVNFEKIKDGVRDLANKVLTIQAQGDYMAAKNLLETYAVESEPIMIMRARLQELPVDIKPIFQIEKELG 6eom A 2.10 BS02 ALA A 1 L318 A319 L287 A288 H1XW48 29420664 LKRMIAQFAPTEIKYDHSLLDERKQKVVENLYRAAKIMDEIFLDQVYSKNFEIREQLRASSDPLDQLRLEYFTIMFGPFDRLNHDKPFIGNTPKPKGANFYPPDMTREEFENWLKAHPEDEAAFTSEFTVIRRQDGKLVAIPYSEYYKEYLTRAADYLKKAAEFADNPSLKKYLQLRAEAFLNNDYYESDLAWMDLNDHTIEVVIGPYEVYEDKLFNYKAAFEAFITLRDPVESAKLKKFVGYLDEMEKNLPIPDAYKNFNRGSESPMVVVQEVFSAGDTKAGVQTLAFNLPNDERVREAKGSKKVMLKNIHEAKFDKLLKPIAEKVLFAEQLPLVTFEGFFNHTLMHEISHGLGPGKIVLNGRQTEVKKELKETYSSIEECKADVLGMYNNLFMIEKGVYPPEFEKQIYVTFLAGIFRTIRFGINEAHGAGNAVIFNYLLEKGAYQFDPAAHRVKVNFEKIKDGVRDLANKVLTIQAQGDYMAAKNLLETYAVESEPIMIMRARLQELPVDIKPIFQIEKELG 6eom A 2.10 BS03 LYS A 1 V315 L318 K346 R450 F454 V284 L287 K315 R419 F423 H1XW48 29420664 LKRMIAQFAPTEIKYDHSLLDERKQKVVENLYRAAKIMDEIFLDQVYSKNFEIREQLRASSDPLDQLRLEYFTIMFGPFDRLNHDKPFIGNTPKPKGANFYPPDMTREEFENWLKAHPEDEAAFTSEFTVIRRQDGKLVAIPYSEYYKEYLTRAADYLKKAAEFADNPSLKKYLQLRAEAFLNNDYYESDLAWMDLNDHTIEVVIGPYEVYEDKLFNYKAAFEAFITLRDPVESAKLKKFVGYLDEMEKNLPIPDAYKNFNRGSESPMVVVQEVFSAGDTKAGVQTLAFNLPNDERVREAKGSKKVMLKNIHEAKFDKLLKPIAEKVLFAEQLPLVTFEGFFNHTLMHEISHGLGPGKIVLNGRQTEVKKELKETYSSIEECKADVLGMYNNLFMIEKGVYPPEFEKQIYVTFLAGIFRTIRFGINEAHGAGNAVIFNYLLEKGAYQFDPAAHRVKVNFEKIKDGVRDLANKVLTIQAQGDYMAAKNLLETYAVESEPIMIMRARLQELPVDIKPIFQIEKELG 6f09 P 1.59 BS01 III A 1 N42 S45 V46 R56 R127 Y128 P165 I166 L172 N173 V176 E180 L220 D223 N224 W228 N40 S43 V44 R54 R125 Y126 P162 I163 L169 N170 V173 E177 L217 D220 N221 W225 P63104 29473952 DKNELVQKAKLAEQAERYDDMAACMKSVTEQGELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAADDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 6f09 Q 1.59 BS01 III B 1 N42 V46 R56 R60 R127 Y128 G169 L172 N173 V176 E180 D213 L216 L220 D223 N224 L227 W228 N41 V45 R55 R59 R123 Y124 G165 L168 N169 V172 E176 D209 L212 L216 D219 N220 L223 W224 P63104 29473952 DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEAEQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWT 6f09 R 1.59 BS01 III C 1 K49 R56 R60 K120 R127 Y128 G169 L172 N173 V176 L216 L220 D223 N224 L227 W228 K48 R55 R59 K118 R125 Y126 G167 L170 N171 V174 L211 L215 D218 N219 L222 W223 P63104 29473952 DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIALDSEESYKDSTLIMQLLRDNLTLWTS 6f09 S 1.59 BS01 III D 1 K49 R56 R60 K120 R127 Y128 G169 L172 N173 V176 Y179 E180 D213 L216 L220 N224 L227 W228 K48 R55 R59 K119 R126 Y127 G167 L170 N171 V174 Y177 E178 D211 L214 L218 N222 L225 W226 P63104 29473952 DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 6f1x A 1.90 BS01 C9Q A 1 Y7 T8 L9 F27 N33 G34 F72 M81 M116 W117 D119 D120 W123 F124 Y5 T6 L7 F25 N31 G32 F70 M79 M114 W115 D117 D118 W121 F122 3.6.1.55,3.6.1.56 P36639 29485874 ASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 6f1x B 1.90 BS01 C9Q B 1 Y7 T8 L9 L11 N33 G34 F72 M81 W117 D119 D120 F124 Y6 T7 L8 L10 N32 G33 F71 M80 W116 D118 D119 F123 3.6.1.55,3.6.1.56 P36639 29485874 GASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 6f20 A 2.00 BS01 C9E A 1 T8 L9 N33 F72 M81 W117 D119 D120 T8 L9 N33 F72 M81 W117 D119 D120 3.6.1.55,3.6.1.56 P36639 29485874 MGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 6f20 B 2.00 BS01 C9E B 1 T8 L9 F27 N33 F72 M81 W117 D119 D120 T5 L6 F24 N30 F69 M78 W114 D116 D117 3.6.1.55,3.6.1.56 P36639 29485874 SRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 6f22 A 1.55 BS01 C9B A 1 T8 L9 F27 N33 G36 G37 F72 M81 W117 D119 D120 T9 L10 F28 N34 G37 G38 F73 M82 W118 D120 D121 3.6.1.55,3.6.1.56 P36639 29485874 HMGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 6f22 B 1.55 BS01 C9B B 1 T8 L9 K23 F27 N33 G36 F72 M81 W117 D119 D120 T6 L7 K21 F25 N31 G34 F70 M79 W115 D117 D118 3.6.1.55,3.6.1.56 P36639 29485874 ASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 6f23 A 1.84 BS01 C8Z A 1 T8 L9 F27 F72 M81 W117 D119 D120 T11 L12 F30 F75 M84 W120 D122 D123 3.6.1.55,3.6.1.56 P36639 29485874 GSHMGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 6f23 B 1.84 BS01 C8Z B 1 T8 F27 F72 M81 W117 D119 D120 F139 T6 F25 F70 M79 W115 D117 D118 F137 3.6.1.55,3.6.1.56 P36639 29485874 ASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV 6f9r A 1.85 BS01 FUC A 1 N416 D417 T418 N413 D414 T415 3.2.1.-,3.4.15.1 P12821 29476645 LDPGLQPGQFSADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMVGLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEG 6f9r A 1.85 BS03 D0W A 1 Q259 H331 A332 S333 A334 T358 H361 E362 H365 Y369 E389 D393 F435 K489 H491 Y498 Y501 F505 Q256 H328 A329 S330 A331 T355 H358 E359 H362 Y366 E386 D390 F432 K486 H488 Y495 Y498 F502 3.2.1.-,3.4.15.1 P12821 29476645 LDPGLQPGQFSADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMVGLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEG 6f9t A 1.60 BS03 D0Z A 1 Q281 A354 S355 A356 H383 E384 H387 E403 H410 E411 F457 K511 H513 Y520 Y523 F527 Q242 A315 S316 A317 H344 E345 H348 E364 H371 E372 F418 K472 H474 Y481 Y484 F488 3.2.1.-,3.4.15.1 P12821 29476645 DEAEASKFVEEYDRTSQVVWNEYAGANWNYNTNITTETSKILLQKNMQIAQHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPQGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWQKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPQMSASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTPNS 6f9u A 1.90 BS03 D0W A 1 Q281 H353 A354 S355 A356 V380 H383 E384 H387 E411 F457 K511 H513 Y520 Y523 F527 Q242 H314 A315 S316 A317 V341 H344 E345 H348 E372 F418 K472 H474 Y481 Y484 F488 3.2.1.-,3.4.15.1 P12821 29476645 DEAEASKFVEEYDRTSQVVWNEYAGANWNYNTNITTETSKILLQKNMQIAQHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPQGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWQKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPQMSASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTPNS 6f9v A 1.69 BS02 D0Z A 1 Q259 H331 A332 S333 A334 T358 H361 E362 H365 Y369 R381 H388 E389 D393 F435 K489 H491 Y498 Y501 F505 Q255 H327 A328 S329 A330 T354 H357 E358 H361 Y365 R377 H384 E385 D389 F431 K485 H487 Y494 Y497 F501 3.2.1.-,3.4.15.1 P12821 29476645 LDPGLQPGQFSADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMVGLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPE 6f9v A 1.69 BS03 FUC A 1 T478 N480 H483 T474 N476 H479 3.2.1.-,3.4.15.1 P12821 29476645 LDPGLQPGQFSADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMVGLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPE 6f9v A 1.69 BS05 MG A 2 E262 D354 E258 D350 3.2.1.-,3.4.15.1 P12821 29476645 LDPGLQPGQFSADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMVGLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPE 6f9v B 1.69 BS02 D0Z B 1 Q259 H331 A332 S333 A334 T358 H361 E362 H365 Y369 H388 E389 F435 K489 H491 Y498 Y501 Q254 H326 A327 S328 A329 T353 H356 E357 H360 Y364 H383 E384 F430 K484 H486 Y493 Y496 3.2.1.-,3.4.15.1 P12821 29476645 LDPGLQPGQFSADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLTCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMVGLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPE 6ffh A 2.65 BS01 D7W A 1 G624 I625 G628 I651 S654 P655 S658 Y659 L1744 W1785 F1788 M1802 S1805 V1806 S1809 A1810 A1813 G57 I58 G61 I84 S87 P88 S91 Y92 L326 W367 F370 M384 S387 V388 S391 A392 A395 3.2.1.17 P41594 29455526 SPVQYLRWGDPAPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTYRAARILAMSKKNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYKISACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPEVYLICNTTNLGVVAPLGYNGLLILACTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERN 6ffi A 2.20 BS01 D8B A 1 G624 I625 S654 P655 S658 Y659 L904 I944 W945 F948 S965 V966 S969 A973 G57 I58 S87 P88 S91 Y92 L322 I362 W363 F366 S383 V384 S387 A391 3.2.1.17 P41594 29455526 SPVQYLRWGDPAPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTYRAARILAMSKKNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYKISACAQLVIAFILICIQLGIIVALFIMEPPDIMEVYLICNTTNLGVVAPLGYNGLLILACTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERN 6flp C 4.10 BS01 NUC N 1 R151 R200 R542 V547 R150 R199 R541 V546 2.7.7.6 P0A8V2 VYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE 6flp C 4.10 BS02 NUC R 1 Q510 Q513 R687 Q688 H1237 Q509 Q512 R686 Q687 H1209 2.7.7.6 P0A8V2 VYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE 6flp C 4.10 BS03 NUC T 1 R143 R202 K203 K496 S508 F514 G1261 K1262 R1269 M1273 R142 R201 K202 K495 S507 F513 G1233 K1234 R1241 M1245 2.7.7.6 P0A8V2 VYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE 6flp D 4.10 BS01 NUC N 1 R47 L120 P131 L132 R278 T317 R1148 K1170 R32 L105 P116 L117 R263 T302 R1107 K1129 2.7.7.6 P0A8T7 EFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTSSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAA 6flp D 4.10 BS02 NUC R 1 V253 R322 Q335 P427 D462 D464 V238 R307 Q320 P412 D447 D449 2.7.7.6 P0A8T7 EFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTSSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAA 6flp D 4.10 BS03 NUC T 1 S210 E211 A261 K332 K334 R339 R352 T790 A791 G794 Y795 S195 E196 A246 K317 K319 R324 R337 T775 A776 G779 Y780 2.7.7.6 P0A8T7 EFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTSSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAA 6flp D 4.10 BS05 ZN D 1 C70 L71 C72 C55 L56 C57 2.7.7.6 P0A8T7 EFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTSSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAA 6fnu A 1.56 BS01 FAD A 1 T49 W50 A52 H78 T80 L105 L107 R108 G109 Y129 A130 A150 Y152 H156 D171 Y174 E177 K178 I187 Q189 Y286 T55 W56 A58 H84 T86 L111 L113 R114 G115 Y130 A131 A151 Y153 H157 D166 Y169 E172 K173 I182 Q184 Y281 1.5.1.20 P46151 NLYFQSMSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKTLTLASLAQQTLNIPVCMHLTCTNTEKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDSPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGQDPLKDLVYLKEKVEAGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPPAILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQS