4r04 A 3.26 BS01 ZN A 1 E544 D545 H655 C700 H759 E541 D542 H652 C697 H756 P16154 ISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENKYLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWIGGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEIQNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDETVLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLALKNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENFDKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGSYLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIAPYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLSQLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKIPSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLSDDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLDTIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIGANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPGLASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDDLIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVETEKEIFSKYSEHITKEISTIKNSIITDVNGQLDHTSQVNTLNAAFFIQSLIDYSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEGIPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIGAEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKILVPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSIYSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPGKFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGAGGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDINKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNYLISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILEFYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKVNGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTLVGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDISTSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKVNINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKDIKKLSLGYIMSNFKSFNS 4u40 A 2.30 BS01 ANP A 1 G32 N33 T35 V39 A52 K54 M105 E106 C108 S112 D153 K155 Q157 N158 L160 D171 G16 N17 T19 V23 A36 K38 M89 E90 C92 S96 D137 K139 Q141 N142 L144 D155 2.7.11.1 O95819 SLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRK 4u40 A 2.30 BS02 MG A 1 N158 D171 N142 D155 2.7.11.1 O95819 SLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRK 4u40 A 2.30 BS03 MG A 2 S77 H79 I82 A83 T84 S61 H63 I66 A67 T68 2.7.11.1 O95819 SLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRK 4u40 A 2.30 BS04 MG A 3 Q157 N158 V170 D171 Q141 N142 V154 D155 2.7.11.1 O95819 SLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRK 4u41 A 2.20 BS01 3C8 A 1 Y36 V39 A52 I53 K54 L103 M105 E106 F107 C108 L160 V170 D171 Y21 V24 A37 I38 K39 L79 M81 E82 F83 C84 L136 V146 D147 2.7.11.1 O95819 SSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEIKLEINMLKKYSHHRNIATYYGAFIKKSDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTR 4u41 A 2.20 BS02 MG A 1 S77 H79 I82 T84 S57 H59 I62 T64 2.7.11.1 O95819 SSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEIKLEINMLKKYSHHRNIATYYGAFIKKSDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTR 4u42 A 2.50 BS01 3C8 A 1 Y36 V39 A52 K54 L73 L103 M105 E106 F107 C108 L160 V170 D171 Y21 V24 A37 K39 L58 L88 M90 E91 F92 C93 L145 V155 D156 2.7.11.1 O95819 SSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTR 4u42 A 2.50 BS02 MG A 1 S77 H78 H79 R80 I82 T84 S62 H63 H64 R65 I67 T69 2.7.11.1 O95819 SSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTR 4u42 B 2.50 BS01 3C8 B 1 Y36 V39 A52 K54 L103 M105 E106 F107 C108 L160 V170 D171 Y20 V23 A36 K38 L69 M71 E72 F73 C74 L126 V136 D137 2.7.11.1 O95819 SLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTKYSHHRNIATYYGAFIKKSPPDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTR 4u42 B 2.50 BS02 MG B 1 S77 H78 H79 I82 T84 E106 K168 S46 H47 H48 I51 T53 E72 K134 2.7.11.1 O95819 SLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTKYSHHRNIATYYGAFIKKSPPDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTR 4xh0 A 1.99 BS01 ADP A 1 I23 R38 I82 D83 L84 L85 L135 I148 I16 R31 I75 D76 L77 L78 L128 I141 2.7.11.1 Q6FS46 LRVGRKFRIGRKIGDIYHGTNLISGEEVAIRLESIRSRHPQLDYESRVYKYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRKFSFKTVIMLALQMICRVQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYMLIYFCKGSLPWQGLKATTKKQKYDRILEKKLCISVETLCAGLPLEFSEYMNYCRNLKFDERPDYLYLARLFKDLSIKLEYHNDHLFDWTMLRYTKAMVEKNDSFNKVKLLAMKKFASHFHYCKNDDKHYPTPEEIKQQTVQNNNAAPELLSAIDK 4xhg A 2.15 BS01 ADP A 1 I15 S17 G18 I23 A36 R38 D83 L84 L85 L135 I148 I14 S16 G17 I22 A35 R37 D82 L83 L84 L134 I147 Q6FS46 DLRVGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIRLESIRSRHPQLDYESRVYKYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRKFSFKTVIMLALQMICRVQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYMLIYFCKGSLPWQGLKATTKKQKYDRILEKKLCISVETLCAGLPLEFSEYMNYCRNLKFDERPDYLYLARLFKDLSIKLEYHNDHLFDWTMLRYTKAMVEKKNDSFNKVKLLAMKKFASHFHYCKNDDKHYPTPEEIKQQTVQNNNAAPELLSAIDK 4xhl A 3.01 BS01 CKI A 1 I15 I23 A36 Y56 D83 L85 P87 S88 D91 L135 I148 I11 I14 A27 Y47 D74 L76 P78 S79 D82 L126 I139 2.7.11.1 P29295 VGRKFRIGRKIGDIYHGTNLISGEEVAIRLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFLARLFKDLSIKLEYHNDHLFDWTMLRYTKAMTFNKIKLLAMKKFPTHFHYYKNEDKHNPSPEEIKQQTILN 4y6l A 1.60 BS01 III C 1 F96 F119 F131 L138 P140 F143 I169 D170 H187 F190 I232 V233 F235 G236 E237 S238 L239 F244 Q265 V266 Q267 P268 F41 F56 F68 L75 P77 F80 I106 D107 H124 F127 I169 V170 F172 G173 E174 S175 L176 F181 Q202 V203 Q204 P205 3.5.1.- Q8IXJ6 25897714 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 4y6l A 1.60 BS02 ZN A 1 C195 C200 C221 C224 C132 C137 C158 C161 3.5.1.- Q8IXJ6 25897714 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 4y6l B 1.60 BS01 III D 1 F96 R97 F131 A135 L138 Y139 F143 I169 D170 H187 F190 I232 V233 F235 G236 E237 L239 F244 Q265 V266 Q267 P268 F42 R43 F63 A67 L70 Y71 F75 I101 D102 H119 F122 I164 V165 F167 G168 E169 L171 F176 Q197 V198 Q199 P200 3.5.1.- Q8IXJ6 25897714 KERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 4y6l B 1.60 BS02 ZN B 1 C195 C200 C221 C224 C127 C132 C153 C156 3.5.1.- Q8IXJ6 25897714 KERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 4y6o A 1.60 BS01 III C 1 F96 E116 F119 F143 I169 H187 F190 I232 V233 F235 G236 E237 S238 L239 A241 F244 Q265 V266 Q267 P268 F40 E52 F55 F79 I105 H123 F126 I168 V169 F171 G172 E173 S174 L175 A177 F180 Q201 V202 Q203 P204 3.5.1.- Q8IXJ6 25897714 RLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 4y6o A 1.60 BS02 ZN A 1 C195 C200 C221 C224 C131 C136 C157 C160 3.5.1.- Q8IXJ6 25897714 RLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 4y6o B 1.60 BS01 III D 1 F96 R97 F119 F131 A135 F143 I169 D170 H187 F190 I232 V233 F235 G236 E237 S238 L239 A241 F244 Q265 V266 Q267 P268 F42 R43 F53 F65 A69 F77 I103 D104 H121 F124 I166 V167 F169 G170 E171 S172 L173 A175 F178 Q199 V200 Q201 P202 3.5.1.- Q8IXJ6 25897714 KERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 4y6o B 1.60 BS02 ZN B 1 C195 C200 C221 C224 C129 C134 C155 C158 3.5.1.- Q8IXJ6 25897714 KERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 4y6q A 1.90 BS01 ZN A 1 C195 C200 C221 C224 C140 C145 C166 C169 3.5.1.- Q8IXJ6 25897714 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 4y6q A 1.90 BS02 OMR A 1 G84 A85 G86 T89 D95 F96 R97 Y104 F119 L138 P140 F143 Q167 I169 H187 F190 I232 F235 G261 T262 S263 V266 N286 K287 E288 G322 E323 C324 G29 A30 G31 T34 D40 F41 R42 Y49 F64 L83 P85 F88 Q112 I114 H132 F135 I177 F180 G206 T207 S208 V211 N231 K232 E233 G254 E255 C256 3.5.1.- Q8IXJ6 25897714 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 4y6q B 1.90 BS01 ZN B 1 C195 C200 C221 C224 C140 C145 C166 C169 3.5.1.- Q8IXJ6 25897714 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 4y6q B 1.90 BS02 OMR B 1 G84 A85 G86 T89 D95 F96 R97 Y104 F119 L138 P140 Q167 I169 H187 F190 I232 F235 G261 T262 S263 V266 N286 K287 E288 G322 E323 C324 G29 A30 G31 T34 D40 F41 R42 Y49 F64 L83 P85 Q112 I114 H132 F135 I177 F180 G206 T207 S208 V211 N231 K232 E233 G254 E255 C256 3.5.1.- Q8IXJ6 25897714 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQ 4y6q C 1.90 BS01 ZN C 1 C195 C200 C221 C224 C140 C145 C166 C169 3.5.1.- Q8IXJ6 25897714 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDA 4y6q C 1.90 BS02 OMR C 1 G84 A85 G86 T89 D95 F96 R97 Y104 F119 L138 P140 Q167 I169 H187 F190 F235 G261 T262 S263 V266 N286 K287 E288 G322 E323 C324 G29 A30 G31 T34 D40 F41 R42 Y49 F64 L83 P85 Q112 I114 H132 F135 F180 G206 T207 S208 V211 N231 K232 E233 G254 E255 C256 3.5.1.- Q8IXJ6 25897714 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDA 4y6q D 1.90 BS01 ZN D 1 C195 C200 C221 C224 C126 C131 C152 C155 3.5.1.- Q8IXJ6 25897714 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDA 4y6q D 1.90 BS02 OMR D 1 G84 A85 G86 T89 D95 R97 F119 L138 I169 H187 F190 G261 T262 S263 V266 N286 K287 E288 G322 E323 C324 G29 A30 G31 T34 D40 R42 F50 L69 I100 H118 F121 G192 T193 S194 V197 N217 K218 E219 G240 E241 C242 3.5.1.- Q8IXJ6 25897714 ERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDA 4yye A 2.30 BS01 NUC C 1 Q44 A165 S166 G167 A168 S170 G171 V355 N356 T357 K358 N400 E401 P402 V403 G404 Y405 I407 K408 I411 I420 G422 D423 E424 E425 N432 R434 F442 Q9 A130 S131 G132 A133 S135 G136 V311 N312 T313 K314 N356 E357 P358 V359 G360 Y361 I363 K364 I367 I376 G378 D379 E380 E381 N388 R390 F398 6.1.1.3 P07236 26704982 ATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPSNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIELEKNYK 4yye A 2.30 BS02 NUC D 1 K96 K123 K142 K143 D144 S146 Y147 N148 K306 Q308 N310 K61 K88 K107 K108 D109 S111 Y112 N113 K262 Q264 N266 6.1.1.3 P07236 26704982 ATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPSNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIELEKNYK 4yye A 2.30 BS03 ZN A 1 C133 H184 H319 C98 H149 H275 6.1.1.3 P07236 26704982 ATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPSNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIELEKNYK 4yye A 2.30 BS04 TSB A 1 M131 C133 R162 E164 T173 R174 L175 F178 Q180 D182 H184 Y270 Q287 V288 T290 Q292 H319 G324 S325 R328 M96 C98 R127 E129 T138 R139 L140 F143 Q145 D147 H149 Y226 Q243 V244 T246 Q248 H275 G280 S281 R284 6.1.1.3 P07236 26704982 ATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPSNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIELEKNYK 4yye B 2.30 BS01 NUC C 1 K96 K123 K142 K143 D144 S146 Y147 N148 K306 Q308 N310 Y312 K61 K88 K107 K108 D109 S111 Y112 N113 K262 Q264 N266 Y268 6.1.1.3 P07236 26704982 ATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPSNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNKSFEKLTMSQIWEKFIELEKNYK 4yye B 2.30 BS02 NUC D 1 A36 Q44 P56 A165 S166 G167 A168 L169 S170 G171 V355 N356 T357 N400 E401 P402 V403 G404 Y405 I407 K408 I411 I420 G422 D423 E424 E425 N432 R434 F442 A1 Q9 P21 A130 S131 G132 A133 L134 S135 G136 V311 N312 T313 N356 E357 P358 V359 G360 Y361 I363 K364 I367 I376 G378 D379 E380 E381 N388 R390 F397 6.1.1.3 P07236 26704982 ATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPSNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNKSFEKLTMSQIWEKFIELEKNYK 4yye B 2.30 BS03 ZN B 1 C133 H184 H319 C98 H149 H275 6.1.1.3 P07236 26704982 ATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPSNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNKSFEKLTMSQIWEKFIELEKNYK 4yye B 2.30 BS04 TSB B 1 M131 C133 R162 E164 T173 R174 L175 F178 Q180 D182 H184 Y270 Q287 V288 T290 Q292 H319 R320 G324 S325 R328 M96 C98 R127 E129 T138 R139 L140 F143 Q145 D147 H149 Y226 Q243 V244 T246 Q248 H275 R276 G280 S281 R284 6.1.1.3 P07236 26704982 ATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPSNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNKSFEKLTMSQIWEKFIELEKNYK 5cj6 A 2.07 BS01 III B 1 V716 K720 V730 Q733 M734 I737 Q738 M894 E897 I898 V46 K50 V60 Q63 M64 I67 Q68 M220 E223 I224 P10275 26683992 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT 5cj6 A 2.07 BS02 51Y A 1 L701 L704 N705 L707 Q711 M742 M745 M749 R752 F764 M780 L873 T877 M895 L31 L34 N35 L37 Q41 M72 M75 M79 R82 F94 M110 L199 T203 M221 P10275 26683992 PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT 5d8k B 1.73 BS01 NUC A 1 F10 F53 K54 H55 N57 S60 R63 Q64 Y68 R109 F5 F48 K49 H50 N52 S55 R58 Q59 Y63 R104 Q03933 HMPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKV 5d8l B 2.07 BS01 NUC A 1 F10 F53 K54 H55 N57 S60 R63 Q64 Y68 R109 F5 F48 K49 H50 N52 S55 R58 Q59 Y63 R104 Q03933 HMPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKV 5d8l B 2.07 BS02 NUC C 1 K54 R63 N66 R71 K72 K110 K49 R58 N61 R66 K67 K105 Q03933 HMPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKV 5d8l D 2.07 BS01 NUC A 1 R63 N66 R71 K72 K110 R58 N61 R66 K67 K96 Q03933 HMPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIDGPVEFQHPYFKQGQDDLLENIKRKV 5d8l D 2.07 BS02 NUC C 1 A9 F10 F53 K54 H55 N57 S60 R63 Q64 Y68 R109 A4 F5 F48 K49 H50 N52 S55 R58 Q59 Y63 R95 Q03933 HMPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIDGPVEFQHPYFKQGQDDLLENIKRKV 5d8l F 2.07 BS01 NUC E 1 A9 F10 F53 K54 H55 N57 S60 R63 Q64 Y68 R109 A4 F5 F48 K49 H50 N52 S55 R58 Q59 Y63 R96 Q03933 HMPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIDDGPVEFQHPYFKQGQDDLLENIKRKV 5d8l F 2.07 BS02 NUC G 1 R63 N66 R71 K72 K110 R58 N61 R66 K67 K97 Q03933 HMPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIDDGPVEFQHPYFKQGQDDLLENIKRKV 5d8l H 2.07 BS01 NUC E 1 H6 R63 N66 R71 K72 K110 H1 R58 N61 R66 K67 K105 Q03933 HMPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKV 5d8l H 2.07 BS02 NUC G 1 F10 F53 K54 H55 N57 S60 R63 Q64 Y68 R109 F5 F48 K49 H50 N52 S55 R58 Q59 Y63 R104 Q03933 HMPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKV 5e6o A 1.80 BS01 III H 1 D29 I33 Q37 K40 P42 R59 K61 F62 L63 P65 L73 I76 R80 F118 D16 I20 Q24 K27 P29 R46 K48 F49 L50 P52 L60 I63 R67 F105 Q23536 26687600 PGSFKERRPFHERQKDVEEIRSQQPNKVPVIIERFDGERSLPLMDRCKFLVPEHITVAELMSIVRRRLQLHPQQAFFLLVNERSMVSNSMSMSNLYSQERDPDGFVYMVYTSQPAFG 5e6o B 1.80 BS01 III E 1 D29 I33 Q37 K40 P42 R59 K61 F62 L63 P65 L73 R80 F118 D15 I19 Q23 K26 P28 R45 K47 F48 L49 P51 L59 R66 F104 Q23536 26687600 GSFKERRPFHERQKDVEEIRSQQPNKVPVIIERFDGERSLPLMDRCKFLVPEHITVAELMSIVRRRLQLHPQQAFFLLVNERSMVSNSMSMSNLYSQERDPDGFVYMVYTSQPAFG 5e6o C 1.80 BS01 III G 1 D29 Q37 K40 P42 K61 F62 L63 V64 L73 R80 F118 D15 Q23 K26 P28 K47 F48 L49 V50 L59 R66 F104 Q23536 26687600 GSFKERRPFHERQKDVEEIRSQQPNKVPVIIERFDGERSLPLMDRCKFLVPEHITVAELMSIVRRRLQLHPQQAFFLLVNERSMVSNSMSMSNLYSQERDPDGFVYMVYTSQPA 5e6o D 1.80 BS01 III F 1 D29 I33 Q37 K40 P42 K61 F62 L63 L73 R80 F118 D15 I19 Q23 K26 P28 K47 F48 L49 L59 R66 F104 Q23536 26687600 GSFKERRPFHERQKDVEEIRSQQPNKVPVIIERFDGERSLPLMDRCKFLVPEHITVAELMSIVRRRLQLHPQQAFFLLVNERSMVSNSMSMSNLYSQERDPDGFVYMVYTSQPA 5eke A 3.00 BS01 UDP A 1 P10 M11 Y12 E14 D43 K74 D94 A95 D96 P14 M15 Y16 E18 D47 K78 D98 A99 D100 2.4.-.- Q55487 FQSNATIELSIVIPMYNEEDNLEHLFARLLEVLTPLKITYEIICVNDGSKDKTLKQLIDCYQSNRQIKIVNLSRNFGKEIALSAGIDYAQGNAVIPIDADLQDPPELIHELVDKWREGYDIVYATRRSRQGMTEIKIPPNTGDFRLMDRKVVNAIKQLPERTRFMKGLFAWVGYRQTFVLFDRNYWKLWNAALDGIFSFSLLPLKVWTYLGSIISLLSLAYASFLILKTITLGDVPGYASLMVAILFLGGVQLISLGVIGEYLGRVYEEVKARPLYLVSDLWGLEYLP 5eke B 3.00 BS01 UDP B 1 P10 M11 Y12 D43 K74 A95 D96 Q98 P14 M15 Y16 D47 K78 A99 D100 Q102 2.4.-.- Q55487 FQSNATIELSIVIPMYNEEDNLEHLFARLLEVLTPLKITYEIICVNDGSKDKTLKQLIDCYQSNRQIKIVNLSRNFGKEIALSAGIDYAQGNAVIPIDADLQDPPELIHELVDKWREGYDIVYATRRSQFTAKMFYKVIGRMTEIKIPPNTGDFRLMDRKVVNAIKQLPERTRFMKGLFAWVGYRQTFVLFDRTKWNYWKLWNAALDGIFSFSLLPLKVWTYLGSIISLLSLAYASFLILVDVPGYASLMVAILFLGGVQLISLGVIGEYLGRVYEEVKARPLYLVSDLWGLEYLPLEK 5eke B 3.00 BS02 MG B 1 D96 Q98 D100 Q102 2.4.-.- Q55487 FQSNATIELSIVIPMYNEEDNLEHLFARLLEVLTPLKITYEIICVNDGSKDKTLKQLIDCYQSNRQIKIVNLSRNFGKEIALSAGIDYAQGNAVIPIDADLQDPPELIHELVDKWREGYDIVYATRRSQFTAKMFYKVIGRMTEIKIPPNTGDFRLMDRKVVNAIKQLPERTRFMKGLFAWVGYRQTFVLFDRTKWNYWKLWNAALDGIFSFSLLPLKVWTYLGSIISLLSLAYASFLILVDVPGYASLMVAILFLGGVQLISLGVIGEYLGRVYEEVKARPLYLVSDLWGLEYLPLEK 5eke C 3.00 BS01 UDP C 1 P9 M10 Y11 E13 D42 K73 A94 D95 Q97 P14 M15 Y16 E18 D47 K78 A99 D100 Q102 2.4.-.- Q55487 FQSNATIELSIVIPMYNEEDNLEHLFARLLEVLTPLKITYEIICVNDGSKDKTLKQLIDCYQSNRQIKIVNLSRNFGKEIALSAGIDYAQGNAVIPIDADLQDPPELIHELVDKWREGYDIVYATRRSRQGETWVKQFTAKMFYKVIGRMTEIKIPPNTGDFRLMDRKVVNAIKQLPERTRFMKGLFAWVGYRQTFVLFDRNYWKLWNAALDGIFSFSLLPLKVWTYLGSIISLLSLAYASFLILKTITLVDVPGYASLMVAILFLGGVQLISLGVIGEYLGRVYEEVKARPLYLVSDLWGLEYLPL 5eke C 3.00 BS02 MG C 1 D93 D95 Q97 D98 D100 Q102 2.4.-.- Q55487 FQSNATIELSIVIPMYNEEDNLEHLFARLLEVLTPLKITYEIICVNDGSKDKTLKQLIDCYQSNRQIKIVNLSRNFGKEIALSAGIDYAQGNAVIPIDADLQDPPELIHELVDKWREGYDIVYATRRSRQGETWVKQFTAKMFYKVIGRMTEIKIPPNTGDFRLMDRKVVNAIKQLPERTRFMKGLFAWVGYRQTFVLFDRNYWKLWNAALDGIFSFSLLPLKVWTYLGSIISLLSLAYASFLILKTITLVDVPGYASLMVAILFLGGVQLISLGVIGEYLGRVYEEVKARPLYLVSDLWGLEYLPL 5eke D 3.00 BS01 UDP D 1 P10 M11 Y12 E14 D43 N71 K74 A95 D96 P14 M15 Y16 E18 D47 N75 K78 A99 D100 2.4.-.- Q55487 FQSNATIELSIVIPMYNEEDNLEHLFARLLEVLTPLKITYEIICVNDGSKDKTLKQLIDCYQSNRQIKIVNLSRNFGKEIALSAGIDYAQGNAVIPIDADLQDPPELIHELVDKWREGYDIVYATRRTWVKQFTAKMFYKVIGRMTEIKIPPNTGDFRLMDRKVVNAIKQLPERTRFMKGLFAWVGYRQTFVLFWNYWKLWNAALDGIFSFSLLPLKVWTYLGSIISLLSLAYASFLILKDVPGYASLMVAILFLGGVQLISLGVIGEYLGRVYEEVKARPLYLVSDLWGLEYLPL 5eke D 3.00 BS02 MG D 1 D96 Q98 D100 Q102 2.4.-.- Q55487 FQSNATIELSIVIPMYNEEDNLEHLFARLLEVLTPLKITYEIICVNDGSKDKTLKQLIDCYQSNRQIKIVNLSRNFGKEIALSAGIDYAQGNAVIPIDADLQDPPELIHELVDKWREGYDIVYATRRTWVKQFTAKMFYKVIGRMTEIKIPPNTGDFRLMDRKVVNAIKQLPERTRFMKGLFAWVGYRQTFVLFWNYWKLWNAALDGIFSFSLLPLKVWTYLGSIISLLSLAYASFLILKDVPGYASLMVAILFLGGVQLISLGVIGEYLGRVYEEVKARPLYLVSDLWGLEYLPL 5ekh A 1.34 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5ekh A 1.34 BS02 5RD A 1 H94 H96 H119 V121 V135 L198 T199 T200 P202 W209 H91 H93 H116 V118 V131 L194 T195 T196 P198 W205 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5ekj A 1.13 BS01 ZN A 1 H94 H96 H119 H92 H94 H117 4.2.1.1 P00918 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5ekj A 1.13 BS02 TG4 A 1 H94 H96 H119 V121 L198 T199 T200 P202 W209 H92 H94 H117 V119 L195 T196 T197 P199 W206 4.2.1.1 P00918 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5ekm A 1.33 BS01 ZN A 1 H94 H96 H119 H91 H93 H116 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5ekm A 1.33 BS02 TG5 A 1 E69 Q92 H94 H96 H119 F131 L198 T199 T200 W209 E66 Q89 H91 H93 H116 F127 L194 T195 T196 W205 4.2.1.1 P00918 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5ekp C 3.19 BS01 UDP C 1 P10 M11 Y12 D43 K74 A95 D96 Q98 P14 M15 Y16 D47 K78 A99 D100 Q102 2.4.-.- Q55487 FQSNATIELSIVIPMYNEEDNLEHLFARLLEVLTPLKITYEIICVNDGSKDKTLKQLIDCYQSNRQIKIVNLSRNFGKEIALSAGIDYAQGNAVIPIDADLQDPPELIHELVDKWREGYDIVYATRRSRQGETWVKQFTAKMFYKVIGRMTEIKIPPNTGDFRLMDRKVVNAIKQLPERTRFMKGLFAWVGYRQTFVLFDRNYWKLWNFALDGIFSFSLLPLKVWTYLGSIISLLSLAYASFLILKTITLVDVPGYASLMVAILFLGGVQLISLGVIGEYLGRVYEEVKARPLYLVSDLWGLEYLPL 5ekp C 3.19 BS02 MG C 1 D96 Q98 D100 Q102 2.4.-.- Q55487 FQSNATIELSIVIPMYNEEDNLEHLFARLLEVLTPLKITYEIICVNDGSKDKTLKQLIDCYQSNRQIKIVNLSRNFGKEIALSAGIDYAQGNAVIPIDADLQDPPELIHELVDKWREGYDIVYATRRSRQGETWVKQFTAKMFYKVIGRMTEIKIPPNTGDFRLMDRKVVNAIKQLPERTRFMKGLFAWVGYRQTFVLFDRNYWKLWNFALDGIFSFSLLPLKVWTYLGSIISLLSLAYASFLILKTITLVDVPGYASLMVAILFLGGVQLISLGVIGEYLGRVYEEVKARPLYLVSDLWGLEYLPL 5ekp A 3.19 BS01 UDP A 1 P10 M11 Y12 E14 D43 N71 K74 A95 P14 M15 Y16 E18 D47 N75 K78 A99 2.4.-.- Q55487 FQSNATIELSIVIPMYNEEDNLEHLFARLLEVLTPLKITYEIICVNDGSKDKTLKQLIDCYQSNRQIKIVNLSRNFGKEIALSAGIDYAQGNAVIPIDADLQDPPELIHELVDKWREGYDIVYATRRSRQGMTEIKIPPNTGDFRLMDRKVVNAIKQLPERTRFMKGLFAWVGYRQTFVLFDRNYWKLWNFALDGIFSFSLLPLKVWTYLGSIISLLSLAYASFLILKTITLGDVPGYASLMVAILFLGGVQLISLGVIGEYLGRVYEEVKARPLYLVSDLWGLEYLP 5ekp B 3.19 BS01 UDP B 1 P10 M11 Y12 D43 N71 K74 A95 D96 Q98 P14 M15 Y16 D47 N75 K78 A99 D100 Q102 2.4.-.- Q55487 FQSNATIELSIVIPMYNEEDNLEHLFARLLEVLTPLKITYEIICVNDGSKDKTLKQLIDCYQSNRQIKIVNLSRNFGKEIALSAGIDYAQGNAVIPIDADLQDPPELIHELVDKWREGYDIVYATRRSQFTAKMFYKVIGRMTEIKIPPNTGDFRLMDRKVVNAIKQLPERTRFMKGLFAWVGYRQTFVLFDRTKWNYWKLWNFALDGIFSFSLLPLKVWTYLGSIISLLSLAYASFLILVDVPGYASLMVAILFLGGVQLISLGVIGEYLGRVYEEVKARPLYLVSDLWGLEYLPLEK 5ekp B 3.19 BS02 MG B 1 D96 Q98 D100 Q102 2.4.-.- Q55487 FQSNATIELSIVIPMYNEEDNLEHLFARLLEVLTPLKITYEIICVNDGSKDKTLKQLIDCYQSNRQIKIVNLSRNFGKEIALSAGIDYAQGNAVIPIDADLQDPPELIHELVDKWREGYDIVYATRRSQFTAKMFYKVIGRMTEIKIPPNTGDFRLMDRKVVNAIKQLPERTRFMKGLFAWVGYRQTFVLFDRTKWNYWKLWNFALDGIFSFSLLPLKVWTYLGSIISLLSLAYASFLILVDVPGYASLMVAILFLGGVQLISLGVIGEYLGRVYEEVKARPLYLVSDLWGLEYLPLEK 5ekp D 3.19 BS01 UDP D 1 P10 M11 Y12 E14 D43 N71 K74 D94 A95 D96 P14 M15 Y16 E18 D47 N75 K78 D98 A99 D100 2.4.-.- Q55487 FQSNATIELSIVIPMYNEEDNLEHLFARLLEVLTPLKITYEIICVNDGSKDKTLKQLIDCYQSNRQIKIVNLSRNFGKEIALSAGIDYAQGNAVIPIDADLQDPPELIHELVDKWREGYDIVYATRRTWVKQFTAKMFYKVIGRMTEIKIPPNTGDFRLMDRKVVNAIKQLPERTRFMKGLFAWVGYRQTFVLFWNYWKLWNFALDGIFSFSLLPLKVWTYLGSIISLLSLAYASFLILKDVPGYASLMVAILFLGGVQLISLGVIGEYLGRVYEEVKARPLYLVSDLWGLEYLPL 5eqe A 2.40 BS01 5R8 A 1 D306 Q308 Y333 Y354 W420 F435 Y440 D202 Q204 Y229 Y250 W316 F331 Y336 2.7.1.32,2.7.1.82 P35790 26700752 DEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGAIMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV 5eqe B 2.40 BS01 5R8 B 1 D306 Q308 Y333 Y354 W420 W423 I433 F435 Y437 Y440 D193 Q195 Y220 Y241 W307 W310 I320 F322 Y324 Y327 2.7.1.32,2.7.1.82 P35790 26700752 TRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV 5eqp A 2.35 BS01 5R9 A 1 D306 Y333 Y354 W420 W423 F435 Y440 D201 Y228 Y249 W315 W318 F330 Y335 2.7.1.32,2.7.1.82 P35790 26700752 QPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGAEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV 5eqp B 2.35 BS01 5R9 B 1 D306 Q308 Y333 Y354 W420 W423 I433 F435 Y440 D198 Q200 Y225 Y246 W312 W315 I325 F327 Y332 2.7.1.32,2.7.1.82 P35790 26700752 QPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV 5eqy A 2.50 BS01 5RA A 1 D306 Q308 Y333 E349 Y354 F361 W420 W423 E434 F435 D201 Q203 Y228 E244 Y249 F256 W315 W318 E329 F330 2.7.1.32,2.7.1.82 P35790 26700752 QPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGAEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV 5eqy B 2.50 BS01 5RA B 1 D306 Q308 Y333 E349 Y354 W420 W423 I433 E434 F435 D200 Q202 Y227 E243 Y248 W314 W317 I327 E328 F329 2.7.1.32,2.7.1.82 P35790 26700752 QPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGAAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV 5f6m A 1.10 BS01 CA A 1 E70 N72 V75 V76 E80 E52 N54 V57 V58 E62 3.4.21.4 P00760 IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN