2ml1 A BS01 CA A 1 T4 G6 D8 G21 G22 A23 D26 T4 G6 D8 G21 G22 A23 D26 5.1.3.- Q9ZFH0 AQGTDGNDVLIGSDVGEQISGGAGDDRLDGGAGDDLLDGGAGRDRLTGGLGADTFRFALREDSHRSPLGTFSDLILDFDPSQDKIDVSALGFIGLGNGYAGTLAVSLSADGLRTYLKSYDADAQGRSFELALDGNHAATLSAGNIVFAAATPG 2ml1 A BS02 CA A 2 S13 D14 V15 E17 G30 A32 D35 S13 D14 V15 E17 G30 A32 D35 5.1.3.- Q9ZFH0 AQGTDGNDVLIGSDVGEQISGGAGDDRLDGGAGDDLLDGGAGRDRLTGGLGADTFRFALREDSHRSPLGTFSDLILDFDPSQDKIDVSALGFIGLGNGYAGTLAVSLSADGLRTYLKSYDADAQGRSFELALDGNHAATLSAGNIVFAAATPG 2ml1 A BS03 CA A 3 G22 A23 G24 D26 G39 G40 A41 D44 G22 A23 G24 D26 G39 G40 A41 D44 5.1.3.- Q9ZFH0 AQGTDGNDVLIGSDVGEQISGGAGDDRLDGGAGDDLLDGGAGRDRLTGGLGADTFRFALREDSHRSPLGTFSDLILDFDPSQDKIDVSALGFIGLGNGYAGTLAVSLSADGLRTYLKSYDADAQGRSFELALDGNHAATLSAGNIVFAAATPG 2ml1 A BS04 CA A 4 G31 A32 G33 D35 G48 G49 L50 D53 G31 A32 G33 D35 G48 G49 L50 D53 5.1.3.- Q9ZFH0 AQGTDGNDVLIGSDVGEQISGGAGDDRLDGGAGDDLLDGGAGRDRLTGGLGADTFRFALREDSHRSPLGTFSDLILDFDPSQDKIDVSALGFIGLGNGYAGTLAVSLSADGLRTYLKSYDADAQGRSFELALDGNHAATLSAGNIVFAAATPG 2ml1 A BS05 CA A 5 G39 G40 G42 D44 D62 D73 G39 G40 G42 D44 D62 D73 5.1.3.- Q9ZFH0 AQGTDGNDVLIGSDVGEQISGGAGDDRLDGGAGDDLLDGGAGRDRLTGGLGADTFRFALREDSHRSPLGTFSDLILDFDPSQDKIDVSALGFIGLGNGYAGTLAVSLSADGLRTYLKSYDADAQGRSFELALDGNHAATLSAGNIVFAAATPG 2ml1 A BS06 CA A 6 G49 G51 D53 D79 D83 G49 G51 D53 D79 D83 5.1.3.- Q9ZFH0 AQGTDGNDVLIGSDVGEQISGGAGDDRLDGGAGDDLLDGGAGRDRLTGGLGADTFRFALREDSHRSPLGTFSDLILDFDPSQDKIDVSALGFIGLGNGYAGTLAVSLSADGLRTYLKSYDADAQGRSFELALDGNHAATLSAGNIVFAAATPG 2ml2 A BS01 CA A 1 S12 D13 L14 D16 G29 G31 D34 S12 D13 L14 D16 G29 G31 D34 5.1.3.- Q9ZFH0 DPSAEAQPIVGSDLDDQLHGTLLGEEISGGGGADQLYGYGGGDLLDGGAGRDRLTGGEGADTFRFALREDSQRSAAGTFSDLILDFDPTQDKLDVSALGFTGLGNGYAGTLAVSVSDDGTRTYLKSYETDAEGRSFEVSLQGNHAAALSADNILFATPVPV 2ml2 A BS02 CA A 2 G20 T21 L23 E25 E26 G38 G40 D43 G20 T21 L23 E25 E26 G38 G40 D43 5.1.3.- Q9ZFH0 DPSAEAQPIVGSDLDDQLHGTLLGEEISGGGGADQLYGYGGGDLLDGGAGRDRLTGGEGADTFRFALREDSQRSAAGTFSDLILDFDPTQDKLDVSALGFTGLGNGYAGTLAVSVSDDGTRTYLKSYETDAEGRSFEVSLQGNHAAALSADNILFATPVPV 2ml2 A BS03 CA A 3 G29 G30 G31 G32 D34 G47 G48 A49 D52 G29 G30 G31 G32 D34 G47 G48 A49 D52 5.1.3.- Q9ZFH0 DPSAEAQPIVGSDLDDQLHGTLLGEEISGGGGADQLYGYGGGDLLDGGAGRDRLTGGEGADTFRFALREDSQRSAAGTFSDLILDFDPTQDKLDVSALGFTGLGNGYAGTLAVSVSDDGTRTYLKSYETDAEGRSFEVSLQGNHAAALSADNILFATPVPV 2ml2 A BS04 CA A 4 G38 Y39 G40 G41 D43 G56 E58 D61 G38 Y39 G40 G41 D43 G56 E58 D61 5.1.3.- Q9ZFH0 DPSAEAQPIVGSDLDDQLHGTLLGEEISGGGGADQLYGYGGGDLLDGGAGRDRLTGGEGADTFRFALREDSQRSAAGTFSDLILDFDPTQDKLDVSALGFTGLGNGYAGTLAVSVSDDGTRTYLKSYETDAEGRSFEVSLQGNHAAALSADNILFATPVPV 2ml2 A BS05 CA A 5 G48 A49 G50 D52 D70 S80 D81 G48 A49 G50 D52 D70 S80 D81 5.1.3.- Q9ZFH0 DPSAEAQPIVGSDLDDQLHGTLLGEEISGGGGADQLYGYGGGDLLDGGAGRDRLTGGEGADTFRFALREDSQRSAAGTFSDLILDFDPTQDKLDVSALGFTGLGNGYAGTLAVSVSDDGTRTYLKSYETDAEGRSFEVSLQGNHAAALSADNILFATPVPV 2ml2 A BS06 CA A 6 G56 G57 E58 G59 D61 F86 D91 G56 G57 E58 G59 D61 F86 D91 5.1.3.- Q9ZFH0 DPSAEAQPIVGSDLDDQLHGTLLGEEISGGGGADQLYGYGGGDLLDGGAGRDRLTGGEGADTFRFALREDSQRSAAGTFSDLILDFDPTQDKLDVSALGFTGLGNGYAGTLAVSVSDDGTRTYLKSYETDAEGRSFEVSLQGNHAAALSADNILFATPVPV 2ml3 A BS01 CA A 1 G12 S13 L15 D17 G30 G32 D35 G12 S13 L15 D17 G30 G32 D35 5.1.3.- Q9ZFH0 ADPGVEGTPVVGSDLDDELHGTLGSEQILGGGGADQLYGYAGNDLLDGGAGRDKLSGGEGADTFRFALREDSHRSPLGTFGDRILDFDPSQDRIDVSALGFSGLGNGYAGSLAVSVSDDGTRTYLKSYEADAQGLSFEVALEGDHAAALSADNIVFAATDAAAAGELGVIGASGQPDDPTV 2ml3 A BS02 CA A 2 T22 G24 E26 G39 A41 D44 T22 G24 E26 G39 A41 D44 5.1.3.- Q9ZFH0 ADPGVEGTPVVGSDLDDELHGTLGSEQILGGGGADQLYGYAGNDLLDGGAGRDKLSGGEGADTFRFALREDSHRSPLGTFGDRILDFDPSQDRIDVSALGFSGLGNGYAGSLAVSVSDDGTRTYLKSYEADAQGLSFEVALEGDHAAALSADNIVFAATDAAAAGELGVIGASGQPDDPTV 2ml3 A BS03 CA A 3 G30 G31 G32 G33 D35 G48 G49 A50 D53 G30 G31 G32 G33 D35 G48 G49 A50 D53 5.1.3.- Q9ZFH0 ADPGVEGTPVVGSDLDDELHGTLGSEQILGGGGADQLYGYAGNDLLDGGAGRDKLSGGEGADTFRFALREDSHRSPLGTFGDRILDFDPSQDRIDVSALGFSGLGNGYAGSLAVSVSDDGTRTYLKSYEADAQGLSFEVALEGDHAAALSADNIVFAATDAAAAGELGVIGASGQPDDPTV 2ml3 A BS04 CA A 4 Y40 A41 G42 D44 G57 G58 E59 D62 Y40 A41 G42 D44 G57 G58 E59 D62 5.1.3.- Q9ZFH0 ADPGVEGTPVVGSDLDDELHGTLGSEQILGGGGADQLYGYAGNDLLDGGAGRDKLSGGEGADTFRFALREDSHRSPLGTFGDRILDFDPSQDRIDVSALGFSGLGNGYAGSLAVSVSDDGTRTYLKSYEADAQGLSFEVALEGDHAAALSADNIVFAATDAAAAGELGVIGASGQPDDPTV 2ml3 A BS05 CA A 5 G48 G49 G51 D53 D71 D82 G48 G49 G51 D53 D71 D82 5.1.3.- Q9ZFH0 ADPGVEGTPVVGSDLDDELHGTLGSEQILGGGGADQLYGYAGNDLLDGGAGRDKLSGGEGADTFRFALREDSHRSPLGTFGDRILDFDPSQDRIDVSALGFSGLGNGYAGSLAVSVSDDGTRTYLKSYEADAQGLSFEVALEGDHAAALSADNIVFAATDAAAAGELGVIGASGQPDDPTV 2ml3 A BS06 CA A 6 G58 G60 D62 D92 G58 G60 D62 D92 5.1.3.- Q9ZFH0 ADPGVEGTPVVGSDLDDELHGTLGSEQILGGGGADQLYGYAGNDLLDGGAGRDKLSGGEGADTFRFALREDSHRSPLGTFGDRILDFDPSQDRIDVSALGFSGLGNGYAGSLAVSVSDDGTRTYLKSYEADAQGLSFEVALEGDHAAALSADNIVFAATDAAAAGELGVIGASGQPDDPTV 2mrf A BS01 ZN A 1 C204 C207 H219 C223 C10 C13 H25 C29 6.3.2.- Q9NS91 25162118 GSRQVTKVDCPVCGVNIPESHINKHLDSCLSRE 3wiu A 1.80 BS02 CA A 2 L205 D208 V210 D226 L202 D205 V207 D223 3.4.21.- P58502 NTIRVIVSVDKAKFNPHEVLGIGGHIVYQFKLIPAVVVDVPANAVGKLKKMPGVEKVEFDHQAVLLGKPSWLGGGSTQPAQTIPWGIERVKAPSVWSITDGSVSVIQVAVLDTGVDYDHPDLAANIAWCVSTLRGKVSTKLRDCADQNGHGTHVIGTIAALNNDIGVVGVAPGVQIYSVRVLDARGSGSYSDIAIGIEQAILGPDGVADKDGDGIIAGDPDDDAAEVISMSLGGPADDSYLYDMIIQAYNAGIVIVAASGNEGAPSPSYPAAYPEVIAVGAIDSNDNIASFSNRQPEVSAPGVDILSTYPDDSYETLMGTAMATPHVSGVVALIQAAYYQKYGKIAPVGTFDDISKNTVRGILHITADDLGPTGWDADYGYGVVRAALAVQAALG 3wiu C 1.80 BS06 CA C 6 D372 L373 P375 T376 G377 D379 D368 L369 P371 T372 G373 D375 3.4.21.- P58502 NTIRVIVSVDKAKFNPHEVLGIGGHIVYQFKLIPAVVVDVPANAVGKLKKMPGVEKVEFDHQAVLLGKPSWLGGSTQPAQTIPWGIERVKAPSVWSITDGSVSVIQVAVLDTGVDYDHPDLAANIAWCVSTLRGKVSTKLRDCADQNGHGTHVIGTIAALNNDIGVVGVAPGVQIYSVRVLDARGSGSYSDIAIGIEQAILGPDGVADKDGDGIIAGDPDDDAAEVISMSLGGPADDSYLYDMIIQAYNAGIVIVAASGNEGAPSPSYPAAYPEVIAVGAIDSNDNIASFSNRQPEVSAPGVDILSTYPDDSYETLMGTAMATPHVSGVVALIQAAYYQKYGKIAPVGTFDDISKNTVRGILHITADDLGPTGWDADYGYGVVRAALAVQAALG 3wiv C 1.90 BS05 CA C 5 V108 Q110 D226 A227 E229 V107 Q109 D225 A226 E228 3.4.21.- P58502 EQNTIRVIVSVDKAKFNPHEVLGIGGHIVYQFKLIPAVVVDVPANAVGKLKKMPGVEKVEFDHQAVLLGKPSWLGGGSTQPAQTIPWGIERVKAPSVWSITDGSVSVIQVAVLDTGVDYDHPDLAANIAWCVSTLRGKVSTKLRDCADQNGHGTHVIGTIAALNNDIGVVGVAPGVQIYSVRVLDARGSGSYSDIAIGIEQAILGPDGVADKDGDGIIAGDPDDDAAEVISMSLGGPADDSYLYDMIIQAYNAGIVIVAASGNEGAPSPSYPAAYPEVIAVGAIDSNDNIASFSNRQPEVSAPGVDILSTYPDDSYETLMGTAMATPHVSGVVALIQAAYYQKYGKILPVGTFDAISKNTVRGILHITADDLGPTGWDADYGYGVVRAALAVQAALG 3wv5 A 2.20 BS01 2AS A 1 W229 D230 F231 S299 A300 G325 Q326 T327 K330 R331 W207 D208 F209 S273 A274 G299 Q300 T301 K304 R305 6.2.1.- Q76KY2 KDLRYGGLVHDLLADSGKATPNSDAMEDAFGTWTYQELLNHSQAFSAWLDGKGVARGERIVVQLPNIRQTVAVFYGACRRGVVFVPLNPGMKPFHLRSVIADADPRLVIAEDETAADRLRDVTDLPVYSIDSLWADVERLRDAGAGAEAVEVSPEDLAVLIYTSGSTAAPKAVACPHQQIVFAASSINAVLGYHAEDIVFCRMSVSWDFGLYKVLISTLTGAKLVLADIALVKSLRESGATMMPIVPSLASMLTTLIRRDPEGAPTLRMFTNSAAALPQVTIDALRSAFPGAQVVRMYGQTECKRISIMPPHLEHERPDSVGLPLPGTTIEILTLLPPGEPGEITVTGPHVMAGYWRAPEITARAYMRLHTGDYGHLDEDGFLYFGG 3wv5 B 2.20 BS01 2AS B 1 W229 D230 F231 S299 A300 G325 Q326 T327 K330 R331 W206 D207 F208 S259 A260 G285 Q286 T287 K290 R291 6.2.1.- Q76KY2 DLRYGGLVHDLLADSGKATPNSDAMEDAFGTWTYQELLNHSQAFSAWLDGKGVARGERIVVQLPNIRQTVAVFYGACRRGVVFVPLNPGMKPFHLRSVIADADPRLVIAEDETAADRLRDVTDLPVYSIDSLWADVERLRDAGAGAEAVEVSPEDLAVLIYTSGSTAAPKAVACPHQQIVFAASSINAVLGYHAEDIVFCRMSVSWDFGLYKVLISTLTGAKLVLAGVKSLRESGATMMPIVPSLASMLTTTLRMFTNSAAALPQVTIDALRSAFPGAQVVRMYGQTECKRISIMPPHLEHERPDSVGLPLPGTTIEIGEITVTGPHVMAGYWRAPEITARAYMRLHTGDYGHLDFLYF 3wvn A 2.20 BS01 ASP A 1 D230 S299 A300 G325 Q326 K330 R331 D208 S273 A274 G299 Q300 K304 R305 6.2.1.- Q76KY2 KDLRYGGLVHDLLADSGKATPNSDAMEDAFGTWTYQELLNHSQAFSAWLDGKGVARGERIVVQLPNIRQTVAVFYGACRRGVVFVPLNPGMKPFHLRSVIADADPRLVIAEDETAADRLRDVTDLPVYSIDSLWADVERLRDAGAGAEAVEVSPEDLAVLIYTSGSTAAPKAVACPHQQIVFAASSINAVLGYHAEDIVFCRMSVSWDFGLYKVLISTLTGAKLVLADIALVKSLRESGATMMPIVPSLASMLTTLIRRDPEGAPTLRMFTNSAAALPQVTIDALRSAFPGAQVVRMYGQTECKRISIMPPHLEHERPDSVGLPLPGTTIEILTLLPPGEPGEITVTGPHVMAGYWRAPEITARAYMRLHTGDYGHLDEDGFLYFGG 3wvn B 2.20 BS01 ASP B 1 W229 D230 S299 A300 G325 Q326 K330 R331 W206 D207 S260 A261 G286 Q287 K291 R292 6.2.1.- Q76KY2 DLRYGGLVHDLLADSGKATPNSDAMEDAFGTWTYQELLNHSQAFSAWLDGKGVARGERIVVQLPNIRQTVAVFYGACRRGVVFVPLNPGMKPFHLRSVIADADPRLVIAEDETAADRLRDVTDLPVYSIDSLWADVERLRDAGAGAEAVEVSPEDLAVLIYTSGSTAAPKAVACPHQQIVFAASSINAVLGYHAEDIVFCRMSVSWDFGLYKVLISTLTGAKLVLAGLVKSLRESGATMMPIVPSLASMLTTTLRMFTNSAAALPQVTIDALRSAFPGAQVVRMYGQTECKRISIMPPHLEHERVGLPLPGTTIGEITVTGPHVMAGYWRAPEITARAYMRLHTGDYGHLDFLYF 3wvs A 1.40 BS01 HEM A 1 M90 F91 H98 R102 F109 L238 A241 G242 T245 Q249 F282 L287 A292 R295 L318 G345 F346 G347 I350 H351 C353 G355 A359 M82 F83 H90 R94 F101 L230 A233 G234 T237 Q241 F274 L279 A284 R287 L310 G337 F338 G339 I342 H343 C345 G347 A351 G1UDU7 YPESLSYPFGPDEGLALSESYTRARDTDGLIRVKLPYGEPAWLATRYEDARLVLGDARFSRALSEEHDPPRARKFNAQAKSMFNMDAPDHTRLRRLISKAFTIRRVEELRPKVHDLAHRLIDDMLAKGEPADLVADYALPIPTTVICELLGVPFEDREKFGRWTDAILSTSTLNPEEGRVKRMELVGYIGGIIAARRAQPADDLISGMIEARDVQDKLTEQELLDHCIGLLIAGHETTASQIPSFVYALLDQPQHWKRLLDDPELIPSAVEELFRFVPLGSGSAAPRYAREDIEVGGTLVRAGEPVLVALGAANRDGLRFEDPEEIKLDRPSNHHIGFGHGIHHCLGAPLARLELQEALRALLERLPTLKVAGDIAWKSEMMVRGPRSMPVGW 3wvs A 1.40 BS02 RRM A 1 R81 A87 F91 L176 R190 I236 G237 G288 G290 A293 M390 V391 R73 A79 F83 L168 R182 I228 G229 G280 G282 A285 M382 V383 G1UDU7 YPESLSYPFGPDEGLALSESYTRARDTDGLIRVKLPYGEPAWLATRYEDARLVLGDARFSRALSEEHDPPRARKFNAQAKSMFNMDAPDHTRLRRLISKAFTIRRVEELRPKVHDLAHRLIDDMLAKGEPADLVADYALPIPTTVICELLGVPFEDREKFGRWTDAILSTSTLNPEEGRVKRMELVGYIGGIIAARRAQPADDLISGMIEARDVQDKLTEQELLDHCIGLLIAGHETTASQIPSFVYALLDQPQHWKRLLDDPELIPSAVEELFRFVPLGSGSAAPRYAREDIEVGGTLVRAGEPVLVALGAANRDGLRFEDPEEIKLDRPSNHHIGFGHGIHHCLGAPLARLELQEALRALLERLPTLKVAGDIAWKSEMMVRGPRSMPVGW 4c2x A 2.33 BS01 MG A 1 L254 R255 S256 K257 R258 V259 L146 R147 S148 K149 R150 V151 2.3.1.97 O60551 MDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLSDAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPIATCRYWHRSLNPKKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLPSTVMHHPAHKSLKAAYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWRCPGTDSEKVGLVLQ 4c2x A 2.33 BS02 NHW A 1 H115 Y117 Q118 F119 W120 N179 Y180 V181 I245 N246 F247 L248 C249 V250 R255 S256 R258 V259 A260 P261 I264 I267 T268 V271 F277 Q278 A279 Y281 T282 A283 L287 Y479 H7 Y9 Q10 F11 W12 N71 Y72 V73 I137 N138 F139 L140 C141 V142 R147 S148 R150 V151 A152 P153 I156 I159 T160 V163 F169 Q170 A171 Y173 T174 A175 L179 Y371 2.3.1.97 O60551 MDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDKDNVRQEPYSLPQGFMWDTLDLSDAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPKPIATCRYWHRSLNPKKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKTSGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVVESPNGKLTDFLSFYTLPSTVMHHPAHKSLKAAYSFYNIHTETPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWRCPGTDSEKVGLVLQ 4c2y A 1.64 BS02 MG A 1 L254 R255 S256 K257 R258 V259 L140 R141 S142 K143 R144 V145 2.3.1.97 P30419 RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 4c2y B 1.64 BS02 MG B 1 V250 L254 R255 S256 K257 R258 V259 V136 L140 R141 S142 K143 R144 V145 2.3.1.97 P30419 RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 4c2z A 2.08 BS01 MYA A 1 Y117 Q118 F119 W120 Y180 V181 I245 N246 F247 L248 C249 V250 R255 S256 R258 V259 A260 P261 I264 T268 V271 H272 F277 A279 Y281 T282 L287 Y479 Y3 Q4 F5 W6 Y66 V67 I131 N132 F133 L134 C135 V136 R141 S142 R144 V145 A146 P147 I150 T154 V157 H158 F163 A165 Y167 T168 L173 Y365 2.3.1.97 P30419 RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 4c2z A 2.08 BS02 646 A 1 Y180 V181 E182 D183 F188 F190 N246 T282 G284 Y296 H298 F311 S405 L416 Y420 D471 L474 Q496 Y66 V67 E68 D69 F74 F76 N132 T168 G170 Y182 H184 F197 S291 L302 Y306 D357 L360 Q382 2.3.1.97 P30419 RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 4c2z B 2.08 BS02 646 B 1 V181 E182 D183 D184 F188 F190 N246 T282 G284 Y296 H298 F311 S405 Y420 D471 Q496 V67 E68 D69 D70 F74 F76 N132 T168 G170 Y182 H184 F197 S291 Y306 D357 Q382 2.3.1.97 P30419 RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 4c49 A 2.70 BS01 HCY A 1 S19 Q232 R260 I263 N264 S267 F366 H368 W371 S4 Q217 R245 I248 N249 S252 F350 H352 W355 P08185 GLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLRKPIILRFNQPFIIMIFDHFTWSSLFLARVMNPV 4c4x A 2.17 BS01 W9M A 1 F267 D335 Y383 L408 M419 Y466 V498 L499 H524 F33 D101 Y149 L174 M185 Y232 V264 L265 H290 3.3.2.10,3.1.3.76 P34913 SDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 4c4x B 2.17 BS01 W9M B 1 F267 D335 W336 Y383 L408 M419 Y466 V498 L499 H524 F34 D102 W103 Y150 L175 M186 Y233 V265 L266 H291 3.3.2.10,3.1.3.76 P34913 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 4c4y A 2.41 BS01 7WI A 1 F267 D335 W336 M339 T360 Y383 F387 L408 L428 Y466 H524 W525 F34 D102 W103 M106 T127 Y150 F154 L175 L195 Y233 H291 W292 3.3.2.10,3.1.3.76 P34913 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 4c4z A 2.06 BS01 W9L A 1 F267 D335 Y383 L408 M419 Y466 V498 H524 F38 D106 Y154 L179 M190 Y237 V269 H295 3.3.2.10,3.1.3.76 P34913 TSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 4clv A 3.12 BS01 ZN A 1 H38 H42 E63 H119 H35 H39 E60 H116 Q44582 SRTFRLSVSTLVGALVGVLMAIVGVYVTHSTEEPHTSLHEMLHDAVPLDSNEREILELKEEEFTARRREIESRLRAANGKLAESIAKNPQWSPEVEEATREVERAAADLQRATLVHVFEMRAGLKPEHRAAYDRVLVDALKR 4clv A 3.12 BS02 ZN A 2 H42 H46 E60 H39 H43 E57 Q44582 SRTFRLSVSTLVGALVGVLMAIVGVYVTHSTEEPHTSLHEMLHDAVPLDSNEREILELKEEEFTARRREIESRLRAANGKLAESIAKNPQWSPEVEEATREVERAAADLQRATLVHVFEMRAGLKPEHRAAYDRVLVDALKR 4clv A 3.12 BS03 ZN A 3 D52 H131 D49 H128 Q44582 SRTFRLSVSTLVGALVGVLMAIVGVYVTHSTEEPHTSLHEMLHDAVPLDSNEREILELKEEEFTARRREIESRLRAANGKLAESIAKNPQWSPEVEEATREVERAAADLQRATLVHVFEMRAGLKPEHRAAYDRVLVDALKR 4clv A 3.12 BS04 ZN A 4 E43 D47 E40 D44 Q44582 SRTFRLSVSTLVGALVGVLMAIVGVYVTHSTEEPHTSLHEMLHDAVPLDSNEREILELKEEEFTARRREIESRLRAANGKLAESIAKNPQWSPEVEEATREVERAAADLQRATLVHVFEMRAGLKPEHRAAYDRVLVDALKR 4clv A 3.12 BS05 PC A 1 W94 E99 W91 E96 Q44582 SRTFRLSVSTLVGALVGVLMAIVGVYVTHSTEEPHTSLHEMLHDAVPLDSNEREILELKEEEFTARRREIESRLRAANGKLAESIAKNPQWSPEVEEATREVERAAADLQRATLVHVFEMRAGLKPEHRAAYDRVLVDALKR 4clv B 3.12 BS01 ZN A 5 H32 E36 H29 E33 Q44582 SRTFRLSVSTLVGALVGVLMAIVGVYVTHSTEEPHTSLHEMLHDAVPLDSNEREILELKEEEFTARRREIESRLRAANGKLAESIAKNPQWSPEVEEATREVERAAADLQRATLVHVFEMRAGLKPEHRAAYDRVLVDALKR 4cok A 1.69 BS01 TPP A 1 T384 G385 D386 G409 H410 I411 G435 D436 G437 S438 L441 N463 G465 Y466 T467 I468 E469 T377 G378 D379 G402 H403 I404 G428 D429 G430 S431 L434 N456 G458 Y459 T460 I461 E462 4.1.1.1 A9H275 MTYTVGRYLADRLAQIGLKHHFAVAGDYNLVLLDQLLLNTDMQQIYCSNELNCGFSAEGYARANGAAAAIVTFSVGALSAFNALGGAYAENLPVILISGAPNANDHGTGHILHHTLGTTDYGYQLEMARHITCAAESIVAAEDAPAKIDHVIRTALREKKPAYLEIACNVAGAPCVRPGGIDADEASLKAAVDAALAFIEQRGSVTMLVGSRIRAAGAQAQAVALADALGCAVTTMAAAKSFFPEDHPGYRGHYWGEVSSPGAQQAVEGADGVICLAPVFNDYATVGWSAWPKGDNVMLVERHAVTVGGVAYAGIDMRDFLTRLAAHTVRRDATARGGAYVTPQTPAAAPTAPLNNAEMARQIGALLTPRTTLTAETGDSWFNAVRMKLPHGARVELEMQWGHIGWSVPAAFGNALAAPERQHVLMVGDGSFQLTAQEVAQMIRHDLPVIIFLINNHGYTIEVMIHDGPYNNVKNWDYAGLMEVFNAGEGNGLGLRARTGGELAAAIEQARANRNGPTLIECTLDRDDCTQELVTWGKRVAAANARPP 4cok A 1.69 BS02 MG A 1 D436 N463 G465 D429 N456 G458 4.1.1.1 A9H275 MTYTVGRYLADRLAQIGLKHHFAVAGDYNLVLLDQLLLNTDMQQIYCSNELNCGFSAEGYARANGAAAAIVTFSVGALSAFNALGGAYAENLPVILISGAPNANDHGTGHILHHTLGTTDYGYQLEMARHITCAAESIVAAEDAPAKIDHVIRTALREKKPAYLEIACNVAGAPCVRPGGIDADEASLKAAVDAALAFIEQRGSVTMLVGSRIRAAGAQAQAVALADALGCAVTTMAAAKSFFPEDHPGYRGHYWGEVSSPGAQQAVEGADGVICLAPVFNDYATVGWSAWPKGDNVMLVERHAVTVGGVAYAGIDMRDFLTRLAAHTVRRDATARGGAYVTPQTPAAAPTAPLNNAEMARQIGALLTPRTTLTAETGDSWFNAVRMKLPHGARVELEMQWGHIGWSVPAAFGNALAAPERQHVLMVGDGSFQLTAQEVAQMIRHDLPVIIFLINNHGYTIEVMIHDGPYNNVKNWDYAGLMEVFNAGEGNGLGLRARTGGELAAAIEQARANRNGPTLIECTLDRDDCTQELVTWGKRVAAANARPP 4cok A 1.69 BS03 TPP B 1 A25 G26 E50 V75 H114 A25 G26 E50 V75 H114 4.1.1.1 A9H275 MTYTVGRYLADRLAQIGLKHHFAVAGDYNLVLLDQLLLNTDMQQIYCSNELNCGFSAEGYARANGAAAAIVTFSVGALSAFNALGGAYAENLPVILISGAPNANDHGTGHILHHTLGTTDYGYQLEMARHITCAAESIVAAEDAPAKIDHVIRTALREKKPAYLEIACNVAGAPCVRPGGIDADEASLKAAVDAALAFIEQRGSVTMLVGSRIRAAGAQAQAVALADALGCAVTTMAAAKSFFPEDHPGYRGHYWGEVSSPGAQQAVEGADGVICLAPVFNDYATVGWSAWPKGDNVMLVERHAVTVGGVAYAGIDMRDFLTRLAAHTVRRDATARGGAYVTPQTPAAAPTAPLNNAEMARQIGALLTPRTTLTAETGDSWFNAVRMKLPHGARVELEMQWGHIGWSVPAAFGNALAAPERQHVLMVGDGSFQLTAQEVAQMIRHDLPVIIFLINNHGYTIEVMIHDGPYNNVKNWDYAGLMEVFNAGEGNGLGLRARTGGELAAAIEQARANRNGPTLIECTLDRDDCTQELVTWGKRVAAANARPP 4cok B 1.69 BS01 TPP A 1 A25 G26 E50 T72 V75 H114 A25 G26 E50 T72 V75 H114 4.1.1.1 A9H275 MTYTVGRYLADRLAQIGLKHHFAVAGDYNLVLLDQLLLNTDMQQIYCSNELNCGFSAEGYARANGAAAAIVTFSVGALSAFNALGGAYAENLPVILISGAPNANDHGTGHILHHTLGTTDYGYQLEMARHITCAAESIVAAEDAPAKIDHVIRTALREKKPAYLEIACNVAGAPCVRPGGIDADEASLKAAVDAALAFIEQRGSVTMLVGSRIRAAGAQAQAVALADALGCAVTTMAAAKSFFPEDHPGYRGHYWGEVSSPGAQQAVEGADGVICLAPVFNDYATVGWSAWPKGDNVMLVERHAVTVGGVAYAGIDMRDFLTRLAAHTVRRDATARGGAYVTPQTPAAAPTAPLNNAEMARQIGALLTPRTTLTAETGDSWFNAVRMKLPHGARVELEMQWGHIGWSVPAAFGNALAAPERQHVLMVGDGSFQLTAQEVAQMIRHDLPVIIFLINNHGYTIEVMIHDGPYNNVKNWDYAGLMEVFNAGEGNGLGLRARTGGELAAAIEQARANRNGPTLIECTLDRDDCTQELVTWGKRVAAANARPPR 4cxw A 3.10 BS01 6MK A 1 Y106 Y108 L203 V228 H231 H232 D233 E234 V244 Y295 H307 V309 R316 S318 T320 R322 Y80 Y82 L146 V168 H171 H172 D173 E174 V184 Y224 H236 V238 R245 S247 T249 R251 1.14.11.- Q9C0B1 RGSHMTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKDEVDIKSRAAYNVTLLNFMDPQKLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCELEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE 4cxx A 2.76 BS01 640 A 1 I85 R96 Y106 L109 V228 H231 H232 D233 E234 V244 Y295 H307 V309 R316 S318 T320 R322 I59 R70 Y80 L83 V173 H176 H177 D178 E179 V189 Y229 H241 V243 R250 S252 T254 R256 1.14.11.- Q9C0B1 RGSHMTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCELEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEA 4cxy A 2.65 BS01 DGR A 1 R96 Y106 Y108 H231 H232 D233 E234 V244 Y295 H307 V309 R316 S318 R322 R70 Y80 Y82 H177 H178 D179 E180 V190 Y230 H242 V244 R251 S253 R257 1.14.11.- Q9C0B1 RGSHMTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNITEAEIAAACETFLKLNDYLQIETIQALEELAAKEKDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCELEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE 4cyn A 1.40 BS02 A6M A 1 Y80 V81 F90 N167 T203 Y217 F218 H219 Y326 I328 Y345 N376 M377 V378 L399 M420 L421 Y70 V71 F80 N157 T193 Y207 F208 H209 Y316 I318 Y335 N366 M367 V368 L389 M410 L411 2.3.1.97 Q4Q5S8 25238611 AHAFWSTQPVPQTEDETEKIVFAGPMDEPKTVADIPEEPYPIASTFEWWTPNMEAADDIHAIYELLRDNYVEDDDSMFRFNYSEEFLQWALCPPNYIPDWHVAVRRKADKKLLAFIAGVPVTLRMGTPKYMKVKAQEKGEGEEAAKYDEPRHICEINFLCVHKQLREKRLAPILIKEATRRVNRTNVWQAVYTAGVLLPTPYASGQYFHRSLNPEKLVEIRFSGIPAQYQKFQNPMAMLKRNYQLPSAPKNSGLREMKPSDVPQVRRILMNYLDSFDVGPVFSDAEISHYLLPRDGVVFTYVVENDKKVTDFFSFYRIPSTVIGNSNYNLLNAAYVHYYAATSIPLHQLILDLLIVAHSRGFDVCNMVEILDNRSFVEQLKFGAGDGHLRYYFYNWAYPKIKPSQVALVML 4cyn A 1.40 BS03 MYA A 1 H12 A13 F14 W15 N79 Y80 V81 I166 F168 L169 C170 V171 R176 E177 R179 L180 A181 P182 T189 V192 W198 Q199 A200 Y202 T203 L208 Y404 H2 A3 F4 W5 N69 Y70 V71 I156 F158 L159 C160 V161 R166 E167 R169 L170 A171 P172 T179 V182 W188 Q189 A190 Y192 T193 L198 Y394 2.3.1.97 Q4Q5S8 25238611 AHAFWSTQPVPQTEDETEKIVFAGPMDEPKTVADIPEEPYPIASTFEWWTPNMEAADDIHAIYELLRDNYVEDDDSMFRFNYSEEFLQWALCPPNYIPDWHVAVRRKADKKLLAFIAGVPVTLRMGTPKYMKVKAQEKGEGEEAAKYDEPRHICEINFLCVHKQLREKRLAPILIKEATRRVNRTNVWQAVYTAGVLLPTPYASGQYFHRSLNPEKLVEIRFSGIPAQYQKFQNPMAMLKRNYQLPSAPKNSGLREMKPSDVPQVRRILMNYLDSFDVGPVFSDAEISHYLLPRDGVVFTYVVENDKKVTDFFSFYRIPSTVIGNSNYNLLNAAYVHYYAATSIPLHQLILDLLIVAHSRGFDVCNMVEILDNRSFVEQLKFGAGDGHLRYYFYNWAYPKIKPSQVALVML 4cyo A 1.50 BS02 UEK A 1 V81 E82 D83 F88 R89 F90 Y92 N167 T203 Y217 F218 H219 Y326 I328 S330 Y345 N376 M377 V378 L399 L421 V71 E72 D73 F78 R79 F80 Y82 N157 T193 Y207 F208 H209 Y316 I318 S320 Y335 N366 M367 V368 L389 L411 2.3.1.97 Q4Q5S8 25238611 AHAFWSTQPVPQTEDETEKIVFAGPMDEPKTVADIPEEPYPIASTFEWWTPNMEAADDIHAIYELLRDNYVEDDDSMFRFNYSEEFLQWALCPPNYIPDWHVAVRRKADKKLLAFIAGVPVTLRMGTPKYMKVKAQEKGEGEEAAKYDEPRHICEINFLCVHKQLREKRLAPILIKEATRRVNRTNVWQAVYTAGVLLPTPYASGQYFHRSLNPEKLVEIRFSGIPAQYQKFQNPMAMLKRNYQLPSAPKNSGLREMKPSDVPQVRRILMNYLDSFDVGPVFSDAEISHYLLPRDGVVFTYVVENDKKVTDFFSFYRIPSTVIGNSNYNLLNAAYVHYYAATSIPLHQLILDLLIVAHSRGFDVCNMVEILDNRSFVEQLKFGAGDGHLRYYFYNWAYPKIKPSQVALVML 4dav A 2.20 BS01 NUC X 1 N19 R20 F21 R33 L35 K57 G60 K61 T62 R81 N20 R21 F22 R34 L36 K58 G61 K62 T63 R82 Q8U1K8 AMKLMEVSPLFPCIFLRRVNRFVGLVRIKERIERALITNTGRLNEFMIPGRIGYCTPKAGGKTRYILLGFEDHGKIAIIDTRLQGKAFEKIIEKELLPELEGCRIIKREPRVGESRLDYLIECSKGEIFVETKSAVLREGEYAMYPDCPSVRGQRHIKELIKLARDGKRAMIVFIGALPNVSKFKPYKKGDPKIAELLKEALEAGVEIRALGLHMELSGEIIYRGELGVEI 4dav A 2.20 BS02 NUC D 1 F21 T37 N38 T80 E108 S114 R115 R151 R154 H155 F22 T38 N39 T81 E109 S115 R116 R152 R155 H156 Q8U1K8 AMKLMEVSPLFPCIFLRRVNRFVGLVRIKERIERALITNTGRLNEFMIPGRIGYCTPKAGGKTRYILLGFEDHGKIAIIDTRLQGKAFEKIIEKELLPELEGCRIIKREPRVGESRLDYLIECSKGEIFVETKSAVLREGEYAMYPDCPSVRGQRHIKELIKLARDGKRAMIVFIGALPNVSKFKPYKKGDPKIAELLKEALEAGVEIRALGLHMELSGEIIYRGELGVEI 4k41 A 1.40 BS02 ATP A 1 G13 S14 G15 L16 K18 G156 D157 G158 V159 G182 R210 K213 E214 G301 G302 T303 M305 Y306 G9 S10 G11 L12 K14 G144 D145 G146 V147 G170 R198 K201 E202 G289 G290 T291 M293 Y294 P68135 25047814 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 4k41 A 1.40 BS03 KAB A 1 D24 D25 Y133 Y143 A144 S145 G146 R147 G168 Y169 E334 I341 S344 I345 L346 S348 F375 D20 D21 Y121 Y131 A132 S133 G134 R135 G156 Y157 E322 I329 S332 I333 L334 S336 F363 P68135 25047814 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF 4k42 A 2.90 BS01 CA A 1 D11 V339 D7 V325 P68135 25047814 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 4k42 A 2.90 BS02 ADP A 1 G13 S14 G15 L16 K18 G156 D157 G182 R210 K213 E214 G301 G302 M305 Y306 K336 G9 S10 G11 L12 K14 G142 D143 G168 R196 K199 E200 G287 G288 M291 Y292 K322 P68135 25047814 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 4k42 A 2.90 BS03 NWM A 1 Y143 G146 R147 T148 G168 Y169 I345 L349 T351 M355 Y129 G132 R133 T134 G154 Y155 I331 L335 T337 M341 P68135 25047814 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 4k42 B 2.90 BS01 CA B 1 D11 Q137 D154 V339 D7 Q124 D141 V326 P68135 25047814 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 4k42 B 2.90 BS03 NWM B 1 Y133 V139 Y143 G146 G168 Y169 I345 L346 L349 T351 F352 M355 Y120 V126 Y130 G133 G155 Y156 I332 L333 L336 T338 F339 M342 P68135 25047814 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 4k42 C 2.90 BS03 NWM C 1 Y143 G146 T148 G168 Y169 I345 L349 T351 M355 Y130 G133 T135 G155 Y156 I332 L336 T338 M342 P68135 25047814 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 4k42 D 2.90 BS03 NWM D 1 Y133 Y143 G146 T148 G168 Y169 I345 L346 L349 T351 F352 M355 Y119 Y129 G132 T134 G154 Y155 I331 L332 L335 T337 F338 M341 P68135 25047814 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 4k43 A 2.90 BS02 1PO A 1 Y133 Y143 A144 G146 G168 Y169 I345 L349 T351 M355 Y119 Y129 A130 G132 G154 Y155 I331 L335 T337 M341 P68135 25047814 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 4k43 B 2.90 BS03 1PO B 1 V139 Y143 A144 G146 T148 G168 Y169 I345 L349 T351 M355 V125 Y129 A130 G132 T134 G154 Y155 I331 L335 T337 M341 P68135 25047814 TTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKC 4mwz A 1.50 BS01 SAM A 1 Y16 I33 S34 G60 D82 I83 M87 D107 I108 R124 D125 S126 H129 Y8 I25 S26 G52 D74 I75 M79 D99 I100 R116 D117 S118 H121 A5K867 KYLENNQYSDEGIKAYEFIFGEDYISSGGIIATTKILSDIQLDANSKVLDIGSGLGGGCKYINEKYGAHVHGVDICEKMVTIAKLRNQDKAKIEFEAKDILKKDFPESTFDMIYSRDSILHLSYADKKMLFEKCYKWLKPNGILLITDYCADKIENWDEEFKAYIKKRKYTLMPIQEYGDLIKSCKFQNVEAKDISDYWLELLQLELSKLEEKKEEFLKVYSIKEYNSLKDGWTRKIKDTKRDLQKWGYFKAQKM 4mwz B 1.50 BS03 CQA B 1 F28 G29 G36 I39 E209 L210 L213 E214 K217 F29 G30 G37 I40 E210 L211 L214 E215 K218 A5K867 HMISEPVDIKYLENNQYSDEGIKAYEFIFGEDYISSGGIIATTKILSDIQLDANSKVLDIGSGLGGGCKYINEKYGAHVHGVDICEKMVTIAKLRNQDKAKIEFEAKDILKKDFPESTFDMIYSRDSILHLSYADKKMLFEKCYKWLKPNGILLITDYCADKIENWDEEFKAYIKKRKYTLMPIQEYGDLIKSCKFQNVEAKDISDYWLELLQLELSKLEEKKEEFLKVYSIKEYNSLKDGWTRKIKDTKRDLQKWGYFKAQKMI 4mx7 A 2.24 BS01 MX7 A 1 F10 L66 Y73 S76 F77 R79 D80 L84 V85 M88 I96 A102 L116 F120 W142 L143 T156 C168 F171 F4 L60 Y67 S70 F71 R73 D74 L78 V79 M82 I90 A96 L110 F114 W136 L137 T150 C162 F165 P11609 NYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQGKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCEMYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQGTSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPSSADGHRQLVCHVSGFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGLACRVKHSSLGGQDIILYW 4mxb A 1.79 BS01 IM2 A 1 C61 S62 K65 Y97 S123 N125 E159 T209 T228 G229 S230 C41 S42 K45 Y77 S103 N105 E139 T189 T208 G209 S210 3.5.2.6 Q3SAW3 DFEHAISDLEAHNQAKIGVALVSENGNLIQGYRANERFAMCSTFKLPLAALVLSRIDAGEENPERKLHYDSAFLEEYAPAAKRYVATGYMTVTEAIQSALQLSDNAAANLLLKEVGGPPLLTKYFRSLGDKVSRLDRIEPTLNTNTPGDERDTTTPMSMAQTVSKLIFGDTLTYKSKGQLRRLLIGNQTGDKTIRAGLPDSWVTGDKTGSCANGGRNDVAFFITTAGKKYVLSVYTNAPELQGEERALLIASVAKLARQYVVH 4nmp A 1.30 BS01 III C 1 G298 L299 G300 I301 S302 I303 T304 H309 V311 S316 E317 H349 V353 L356 G15 L16 G17 I18 S19 I20 T21 H26 V28 S33 E34 H66 V70 L73 Q9HD26 25136860 GPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYV 4nmp B 1.30 BS01 III D 1 G298 L299 G300 I301 S302 I303 T304 H309 V311 S316 E317 H319 H349 V353 L356 S357 G15 L16 G17 I18 S19 I20 T21 H26 V28 S33 E34 H36 H66 V70 L73 S74 Q9HD26 25136860 GPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYV 4nmq A 1.40 BS01 III C 1 L299 G300 I301 S302 I303 T304 G305 H309 V311 L314 H349 V353 L356 L16 G17 I18 S19 I20 T21 G22 H26 V28 L31 H66 V70 L73 Q9HD26 25136860 GPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYV 4nmq B 1.40 BS01 III D 1 L299 G300 I301 S302 I303 T304 G305 H309 V311 H319 H349 V353 L356 S357 L16 G17 I18 S19 I20 T21 G22 H26 V28 H36 H66 V70 L73 S74 Q9HD26 25136860 GPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVY 4nmr B 1.55 BS01 III D 1 G298 L299 G300 I301 S302 I303 T304 G305 H309 V311 H349 V353 S357 G15 L16 G17 I18 S19 I20 T21 G22 H26 V28 H66 V70 S74 Q9HD26 25136860 GPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYV 4nms A 1.70 BS01 III C 1 G298 L299 G300 I301 S302 I303 T304 H309 V311 L314 H319 H349 V353 L356 G15 L16 G17 I18 S19 I20 T21 H26 V28 L31 H36 H66 V70 L73 Q9HD26 25136860 GPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYV 4o8g A 1.65 BS01 LBV A 1 C24 E27 I29 Y176 M186 F203 H207 T208 P209 A212 Y216 R254 T256 S257 M259 H260 Y263 S272 L273 S274 L286 V288 H290 C21 E24 I26 Y164 M174 F191 H195 T196 P197 A200 Y204 R242 T244 S245 M247 H248 Y251 S260 L261 S262 L274 V276 H278 Q9RZA4 DPLPFFPPLYLGGPEITTENCEREPIHIPGSIQPHGALLTADGHSGEVLQVSLNAATFLGQEPTVLRGQTLAALLPEQWPALQAALPPGCPDALQYRATLDWPGHLSLTVHRVAELLILEFEPTEHALRNAMFALESAPNLRALAEVATQTVRELTGFDRVMLYKFAPDATGEMIAEARREGMQAFLGHRFPASHTPAQARALYTRHLLRLTADTRAAAVPLDPVLNPQTNAPTPLGGAVLRATSPMHMQYLRNMGVGSSLSVSVVVGGQLWGLIVCHHQTPYVLPPDLRTTLEELGRKLSGQVQRKEALE 4o8g A 1.65 BS02 LBW A 1 C24 I29 M186 F198 F203 S206 H207 T208 P209 A212 Y216 R254 T256 S257 H260 Y263 M267 S272 S274 L286 V288 H290 C21 I26 M174 F186 F191 S194 H195 T196 P197 A200 Y204 R242 T244 S245 H248 Y251 M255 S260 S262 L274 V276 H278 Q9RZA4 DPLPFFPPLYLGGPEITTENCEREPIHIPGSIQPHGALLTADGHSGEVLQVSLNAATFLGQEPTVLRGQTLAALLPEQWPALQAALPPGCPDALQYRATLDWPGHLSLTVHRVAELLILEFEPTEHALRNAMFALESAPNLRALAEVATQTVRELTGFDRVMLYKFAPDATGEMIAEARREGMQAFLGHRFPASHTPAQARALYTRHLLRLTADTRAAAVPLDPVLNPQTNAPTPLGGAVLRATSPMHMQYLRNMGVGSSLSVSVVVGGQLWGLIVCHHQTPYVLPPDLRTTLEELGRKLSGQVQRKEALE 4oes A 1.95 BS01 EDT A 1 Y20 M25 W98 R135 W396 Y400 Y20 M25 W98 R135 W396 Y400 Q9AL82 25199691 DPKLNFSWPVNVGPLNPHLYSPNQMFAQNMVYEPLVHYNADGTVGPWLAESWEASQDGRSYTFKLREDVKFSNGEVFDAAAVKANIDTVLQNRPRHNWLELVNQMVSAEVVGPYKVRINLKKPYYPLLQELSLPRPFRFIAPSQFKNGGTADGIVAPIGTGPWKLTETKLGEHDVFTRNDSYWGPKPAYEQITVKVIPDPNTRAIAFEAGEIDLIYGTEGPISPDTFERFQKMGIYNTELSEPLETRVLALNTNHGATKDLAVRKAINHAVDKDTMIATVLYGTQKRADTLFADNVPYANIGLKPYAFDPALAARLLDEAGWTAKASGDIREKDGQPLAIELCFIGTDAISKSMAEIVQADLRKVGIDVKLTGEEESSIYARQRDGRFDMIFNQTWGAPYDPHAFVSSMRVPSHADYQAQLGLPDKAKIDAEIGQVLVSTDETARQALYKDILTRLHEEAVYLPLTSVTAMAVAKPEVGKITFGAMSSEIPFEKLTPK 4oeu A 2.20 BS01 NI A 1 H26 H480 H481 H25 H479 H480 Q0P844 25199691 IPKDTLIIAVENEIARINPAYSEDHDAVINLVFSGLTRFDENMSLKPDLAKSWDISKDGLVYDIFLRDDVLWHDGVKFSADDVKFSIEAFKNPKNNSSIYVNFEDIKSVEILNPSHVKITLFKPYPAFLDALSIGMLPKHLLENENLNTSSFNQNPIGTGPYKFVKWKKGEYVEFKANEHFYLDKVKTPRLIIKHIFDPSIASAELKNGKIDAALIDVSLLNIFKNDENFGILREKSADYRALMFNLDNEFLKDLKVRQALNYAVDKESIVKNLLHDYAFVANHPLERSWANSKNFKIYKYDPKKAEDLLVSAGFKKNKDGNFEKDGKILEFEIWAMSNDPLRVSLAGILQSEFRKIGVVSKVVAKPAGSFDYSKVDSFLIGWGSPLDPDFHTFRVFESSQDSALNDEGWNFGHYHDKKVDIALQKARNTSNLEERKKYYKDFIDALYENPPFIFLAYLDFALVYNKDLKGIKTRTLGHHGVGFTWNVYEWSK 4oeu A 2.20 BS02 HIS A 1 N13 H26 R344 Y374 F380 I382 G383 W384 H480 H481 N12 H25 R343 Y373 F379 I381 G382 W383 H479 H480 Q0P844 25199691 IPKDTLIIAVENEIARINPAYSEDHDAVINLVFSGLTRFDENMSLKPDLAKSWDISKDGLVYDIFLRDDVLWHDGVKFSADDVKFSIEAFKNPKNNSSIYVNFEDIKSVEILNPSHVKITLFKPYPAFLDALSIGMLPKHLLENENLNTSSFNQNPIGTGPYKFVKWKKGEYVEFKANEHFYLDKVKTPRLIIKHIFDPSIASAELKNGKIDAALIDVSLLNIFKNDENFGILREKSADYRALMFNLDNEFLKDLKVRQALNYAVDKESIVKNLLHDYAFVANHPLERSWANSKNFKIYKYDPKKAEDLLVSAGFKKNKDGNFEKDGKILEFEIWAMSNDPLRVSLAGILQSEFRKIGVVSKVVAKPAGSFDYSKVDSFLIGWGSPLDPDFHTFRVFESSQDSALNDEGWNFGHYHDKKVDIALQKARNTSNLEERKKYYKDFIDALYENPPFIFLAYLDFALVYNKDLKGIKTRTLGHHGVGFTWNVYEWSK 4oeu A 2.20 BS03 MG A 1 N31 S134 N30 S133 Q0P844 25199691 IPKDTLIIAVENEIARINPAYSEDHDAVINLVFSGLTRFDENMSLKPDLAKSWDISKDGLVYDIFLRDDVLWHDGVKFSADDVKFSIEAFKNPKNNSSIYVNFEDIKSVEILNPSHVKITLFKPYPAFLDALSIGMLPKHLLENENLNTSSFNQNPIGTGPYKFVKWKKGEYVEFKANEHFYLDKVKTPRLIIKHIFDPSIASAELKNGKIDAALIDVSLLNIFKNDENFGILREKSADYRALMFNLDNEFLKDLKVRQALNYAVDKESIVKNLLHDYAFVANHPLERSWANSKNFKIYKYDPKKAEDLLVSAGFKKNKDGNFEKDGKILEFEIWAMSNDPLRVSLAGILQSEFRKIGVVSKVVAKPAGSFDYSKVDSFLIGWGSPLDPDFHTFRVFESSQDSALNDEGWNFGHYHDKKVDIALQKARNTSNLEERKKYYKDFIDALYENPPFIFLAYLDFALVYNKDLKGIKTRTLGHHGVGFTWNVYEWSK 4oeu B 2.20 BS02 HIS B 1 H26 M338 R344 Y374 F380 I382 G383 W384 H480 H481 H25 M337 R343 Y373 F379 I381 G382 W383 H479 H480 Q0P844 25199691 IPKDTLIIAVENEIARINPAYSEDHDAVINLVFSGLTRFDENMSLKPDLAKSWDISKDGLVYDIFLRDDVLWHDGVKFSADDVKFSIEAFKNPKNNSSIYVNFEDIKSVEILNPSHVKITLFKPYPAFLDALSIGMLPKHLLENENLNTSSFNQNPIGTGPYKFVKWKKGEYVEFKANEHFYLDKVKTPRLIIKHIFDPSIASAELKNGKIDAALIDVSLLNIFKNDENFGILREKSADYRALMFNLDNEFLKDLKVRQALNYAVDKESIVKNLLHDYAFVANHPLERSWANSKNFKIYKYDPKKAEDLLVSAGFKKNKDGNFEKDGKILEFEIWAMSNDPLRVSLAGILQSEFRKIGVVSKVVAKPAGSFDYSKVDSFLIGWGSPLDPDFHTFRVFESSQDSALNDEGWNFGHYHDKKVDIALQKARNTSNLEERKKYYKDFIDALYENPPFIFLAYLDFALVYNKDLKGIKTRTLGHHGVGFTWNVYEWSK 4oev A 1.90 BS02 OXL A 1 H26 M338 R344 F380 I382 G383 W384 H480 H481 H26 M338 R344 F380 I382 G383 W384 H480 H481 Q0P844 25199691 KIPKDTLIIAVENEIARINPAYSEDHDAVINLVFSGLTRFDENMSLKPDLAKSWDISKDGLVYDIFLRDDVLWHDGVKFSADDVKFSIEAFKNPKNNSSIYVNFEDIKSVEILNPSHVKITLFKPYPAFLDALSIGMLPKHLLENENLNTSSFNQNPIGTGPYKFVKWKKGEYVEFKANEHFYLDKVKTPRLIIKHIFDPSIASAELKNGKIDAALIDVSLLNIFKNDENFGILREKSADYRALMFNLDNEFLKDLKVRQALNYAVDKESIVKNLLHDYAFVANHPLERSWANSKNFKIYKYDPKKAEDLLVSAGFKKNKDGNFEKDGKILEFEIWAMSNDPLRVSLAGILQSEFRKIGVVSKVVAKPAGSFDYSKVDSFLIGWGSPLDPDFHTFRVFESSQDSALNDEGWNFGHYHDKKVDIALQKARNTSNLEERKKYYKDFIDALYENPPFIFLAYLDFALVYNKDLKGIKTRTLGHHGVGFTWNVYEWSK 4ofl A 2.70 BS01 HIS A 1 R344 W369 F383 G384 W385 Y406 H482 R342 W367 F381 G382 W383 Y404 H480 Q7CJS8 25199691 HTLQLAIGDEPTEGFDPMLGWSHGSYLLLHSPLLKQNEDFSWDSLLLSQYQPSDDGKTWLLTLKPDLKFSDGSPLTAKDVAFTYNNAAASGGKVDMGNFLSAEVIDPLNVRIHLKAPQSTFVNVLGSLGIVSADKYNAKTYAQKPIGAGPYRLVSFQPGQQMIVEANPYYAGNKNDFDKLIFVFLDEDSAFAAAQSGQLGVVRIPPSMAVGSVNNMKLWVRPSVENRGIVFPTTPAGKKDAHGYPIGNDVTADVAIRRAINYAINRQLLADQIMEGHAIPAYTGVQGLPWNNPDSAIKDGDIDKAKQILEQAGWQLNSQGTREKNGLPAKITLWYTSGDTTRRDLAQALRSMLKPIGIDVDLKSGSWETVERNMHANPTLFGWGSLDPMELYHHYSSNAAGVEYYNPGYYKNPMVDKHLQQALDAPTWQQAVPFWQQVDWDGTTGAGIRGDAAWAWLLNIQHTYLANNCVDLGKGTPEIHGSWSLLNSIDSWKWTC 4ofl B 2.70 BS02 HIS B 2 R344 H482 G483 R342 H480 G481 Q7CJS8 25199691 HTLQLAIGDEPTEGFDPMLGWSHGSYLLLHSPLLKQNEDFSWDSLLLSQYQPSDDGKTWLLTLKPDLKFSDGSPLTAKDVAFTYNNAAASGGKVDMGNFLSAEVIDPLNVRIHLKAPQSTFVNVLGSLGIVSADKYNAKTYAQKPIGAGPYRLVSFQPGQQMIVEANPYYAGNKNDFDKLIFVFLDEDSAFAAAQSGQLGVVRIPPSMAVGSVNNMKLWVRPSVENRGIVFPTTPAGKKDAHGYPIGNDVTADVAIRRAINYAINRQLLADQIMEGHAIPAYTGVQGLPWNNPDSAIKDGDIDKAKQILEQAGWQLNSQGTREKNGLPAKITLWYTSGDTTRRDLAQALRSMLKPIGIDVDLKSGSWETVERNMHANPTLFGWGSLDPMELYHHYSSNAAGVEYYNPGYYKNPMVDKHLQQALDAPTWQQAVPFWQQVDWDGTTGAGIRGDAAWAWLLNIQHTYLANNCVDLGKGTPEIHGSWSLLNSIDSWKWTC 4oso A 2.50 BS01 NAP A 1 G13 S15 R16 G17 I18 H36 Y37 A38 T39 G40 A63 E64 L65 N97 A98 G99 V100 M101 R116 V120 V145 S146 Y160 K164 P190 G191 T193 N195 G12 S14 R15 G16 I17 H35 Y36 A37 T38 G39 A62 E63 L64 N96 A97 G98 V99 M100 R115 V119 V144 S145 Y159 K163 P189 G190 T192 N194 Q9ZGC1 25200607 GNLTGKTALVTGASRGIGRAIAEKLGYAGALVAVHYATGADAAAEVAESIEKDGGRAFTVKAELGVPGDVDVLFEGLERGLKERTGATDLDILVNNAGVMAMGAPEEVTPEMFDRMMAVNAKAPFFIVQRALSVMPDGGRIINVSSGLTRVASPDQVTYGMSKGALEQIALHFSRHLGSRRITVNSVAPGSTDNGSALFQIPEVRETLSQLSTFGEVAEPAAIADVVAFLASEDARWITGAFIDASGGTLLG 4oso A 2.50 BS02 2V4 A 1 M101 S147 G148 L149 Y160 G191 S192 F200 L209 L212 T250 M100 S146 G147 L148 Y159 G190 S191 F199 L208 L211 T249 Q9ZGC1 25200607 GNLTGKTALVTGASRGIGRAIAEKLGYAGALVAVHYATGADAAAEVAESIEKDGGRAFTVKAELGVPGDVDVLFEGLERGLKERTGATDLDILVNNAGVMAMGAPEEVTPEMFDRMMAVNAKAPFFIVQRALSVMPDGGRIINVSSGLTRVASPDQVTYGMSKGALEQIALHFSRHLGSRRITVNSVAPGSTDNGSALFQIPEVRETLSQLSTFGEVAEPAAIADVVAFLASEDARWITGAFIDASGGTLLG 4oso B 2.50 BS01 NAP B 1 G13 S15 R16 G17 I18 H36 A38 T39 G40 A63 L65 N97 V100 M101 R116 V120 V145 S146 Y160 K164 P190 G191 T193 N195 G15 S17 R18 G19 I20 H38 A40 T41 G42 A65 L67 N99 V102 M103 R118 V122 V147 S148 Y162 K166 P192 G193 T195 N197 Q9ZGC1 25200607 HRSGNLTGKTALVTGASRGIGRAIAEKLGYAGALVAVHYATGADAAAEVAESIEKDGGRAFTVKAELGVPGDVDVLFEGLERGLKERTGATDLDILVNNAGVMAMGAPEEVTPEMFDRMMAVNAKAPFFIVQRALSVMPDGGRIINVSSGLTRVASPDQVTYGMSKGALEQIALHFSRHLGSRRITVNSVAPGSTDNGSTLSQLSTFGEVAEPAAIADVVAFLASEDARWITGAFIDASGGTLLG 4oso B 2.50 BS02 2V4 B 1 M101 M103 S147 G148 L149 Q157 Y160 P190 G191 L209 L212 T250 M103 M105 S149 G150 L151 Q159 Y162 P192 G193 L201 L204 T242 Q9ZGC1 25200607 HRSGNLTGKTALVTGASRGIGRAIAEKLGYAGALVAVHYATGADAAAEVAESIEKDGGRAFTVKAELGVPGDVDVLFEGLERGLKERTGATDLDILVNNAGVMAMGAPEEVTPEMFDRMMAVNAKAPFFIVQRALSVMPDGGRIINVSSGLTRVASPDQVTYGMSKGALEQIALHFSRHLGSRRITVNSVAPGSTDNGSTLSQLSTFGEVAEPAAIADVVAFLASEDARWITGAFIDASGGTLLG 4osp A 2.25 BS01 NAP A 1 G13 S15 R16 G17 I18 H36 C37 S38 A63 E64 L65 N97 A98 G99 V100 R116 V120 I145 S146 S147 Y160 K164 P190 G191 I192 T193 N195 G12 S14 R15 G16 I17 H35 C36 S37 A62 E63 L64 N96 A97 G98 V99 R115 V119 I144 S145 S146 Y159 K163 P189 G190 I191 T192 N194 K0IB23 25200607 GKLTGKTALVTGSSRGIGRATAIRLAREGALVAVHCSRNREAADETVATIEKEGGRAFSVLAELGVPGDVHELFLALERGLKERTDATTLDILVNNAGVMGGVAPEEVTPELFDRLVAVNAKAPFFIVQRALTLIPDGGRIINISSGLTRFANPQEVAYAMTKGAMDQLTLHFAKHLGSRNITVNSVGPGITNNGTPVFDNPEAVAQMAGYSVFNRVGEVTDVADVVAFLAGDDARWITGSYLDASGGTLLG 4osp A 2.25 BS02 2V4 A 1 M101 S147 G148 L149 F152 Y160 I192 M100 S146 G147 L148 F151 Y159 I191 K0IB23 25200607 GKLTGKTALVTGSSRGIGRATAIRLAREGALVAVHCSRNREAADETVATIEKEGGRAFSVLAELGVPGDVHELFLALERGLKERTDATTLDILVNNAGVMGGVAPEEVTPELFDRLVAVNAKAPFFIVQRALTLIPDGGRIINISSGLTRFANPQEVAYAMTKGAMDQLTLHFAKHLGSRNITVNSVGPGITNNGTPVFDNPEAVAQMAGYSVFNRVGEVTDVADVVAFLAGDDARWITGSYLDASGGTLLG 4ov0 A 2.00 BS01 RET A 1 Y83 W86 T89 T90 L93 M118 W138 S141 M145 W182 Y185 P186 W189 K216 Y77 W80 T83 T84 L87 M112 W132 S135 M139 W170 Y173 P174 W177 K204 P02945 25192977 RPEWIWLALGTALMGLGTLYFLVKGMGVSDPDAKKFYAITTLVPAIAFTMYLSMLLGYGLTMVPFGGEQNPIYWARYADWLFTTPLLLLDLALLVDADQGTILALVGADGIMIGTGLVGALTKVYSYRFVWWAISTAAMLYILYVLFFGFMRPEVASTFKVLRNVTVVLWSAYPVVWLIGSEGAGIVPLNIETLLFMVLDVSAKVGFGLILLRS 4p0n A 2.08 BS01 1IS A 1 I682 Y683 P702 M703 E711 V712 G715 Q716 F719 I230 Y231 P250 M251 E259 V260 G263 Q264 F267 3.1.4.17,3.1.4.35 Q9Y233 24944747 TLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 4p0n A 2.08 BS02 1IR A 1 L665 I682 Y683 P702 M703 E711 V712 G715 Q716 F719 L213 I230 Y231 P250 M251 E259 V260 G263 Q264 F267 3.1.4.17,3.1.4.35 Q9Y233 24944747 TLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 4p1b A 2.05 BS02 FE A 2 E134 H137 E197 E231 H234 E133 H136 E196 E230 H233 1.14.13.- Q00456 AMHPRKDWYELTRATNWTPSYVTEEQLFPERMSGHMGIPLEKWESYDEPYKTSYPEYVSIQREKDAGAYSVKAALERAKIYENSDPGWISTLKSHYGAIAVGEYAAVTGEGRMARFSKAPGNRNMATFGMMDELRHGQLQLFFPHEYCKKDRQFDWAWRAYHSNEWAAIAAKHFFDDIITGRDAISVAIMLTFSFETGFTNMQFLGLAADAAEAGDYTFANLISSIQTDESRHAQQGGPALQLLIENGKREEAQKKVDMAIWRAWRLFAVLTGPVMDYYTPLEDRSQSFKEFMYEWIIGQFERSLIDLGLDKPWYWDLFLKDIDELHHSYHMGVWYWRTTAWWNPAAGVTPEERDWLEEKYPGWNKRWGRCWDVITENVLNDRMDLVSPETLPSVCNMSQIPLVGVPGDDWNIEVFSLEHNGRLYHFGSEVDRWVFQQDPVQYQNHMNIVDRFLAGQIQPMTLEGALKYMGFQSIEEMGKDAHDFAWADK 4p1b H 2.05 BS01 FES H 1 C45 H47 Q48 I50 C64 A66 H67 W69 C44 H46 Q47 I49 C63 A65 H66 W68 Q00458 SFEKISSLDDIWVGCMETFETSDGTEVLIVNSEEHGVKAYQAMCPHQEILLSEGSYEGGVITCRAHLWTFNDGTGHGINPDDAALAEYPVEVKGDDIYVSTKGILPNKAHS 4p1c I 2.40 BS01 FES I 1 C45 H47 Q48 C64 A66 H67 W69 C44 H46 Q47 C63 A65 H66 W68 Q00458 SFEKISSLDDIWVGEMETFETSDGTEVLIVNSEEHGVKAYQAMCPHQEILLSEGSYEGGVITCRAHLWTFNDGTGHGINPDDAALAEYPVEVKGDDIYVSTKGILPNKAHS 4peu A 1.80 BS02 CA A 2 D154 D178 D119 D143 A3DHD2 DVNAKIVFDNDKVNADNVDGLSVSEREVKITKPGMYTFSGTWNDGQILVDIGKEFEAVLVLDGVNITNTKSAPIYIKSAEKVKIELADGKDNVLTDAEFYEFEDPQDNKPNACIYSRDDITIKGNGNLTVNANFNNGIGTSNDLKITGGNITVKAFNNGLKGNGSVTISGGNIDITAGADGIKVENTEEPHKGYVNITGGTIKIRAKDDAIDSVRSVSINNADVKVSVGGKDVKCEGVLNIAEGCLGKLE 4pfj A 2.30 BS01 NAD A 1 T157 T158 T159 N191 C195 G220 Y221 G222 D223 V224 T242 E243 I244 D245 N248 T275 T276 G277 C278 I281 I299 G300 H301 N346 H353 T155 T156 T157 N189 C193 G218 Y219 G220 D221 V222 T240 E241 I242 D243 N246 T273 T274 G275 C276 I279 I297 G298 H299 N344 H351 3.3.1.1 P23526 DKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQNHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVACAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 4pfj A 2.30 BS02 ADN A 1 L54 H55 T57 E59 T60 D131 E156 T157 K186 D190 H301 L344 L347 M351 G352 H353 M358 S361 F362 L52 H53 T55 E57 T58 D129 E154 T155 K184 D188 H299 L342 L345 M349 G350 H351 M356 S359 F360 3.3.1.1 P23526 DKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQNHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVACAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 4pfj B 2.30 BS02 ADN B 1 H55 T57 E59 T60 Q85 D131 E156 T157 K186 D190 H301 L344 L347 M351 G352 H353 M358 F362 H50 T52 E54 T55 Q80 D126 E151 T152 K181 D185 H296 L339 L342 M346 G347 H348 M353 F357 3.3.1.1 P23526 PYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQNHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVACAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 4pgf B 2.59 BS02 ADN B 1 H55 T57 E59 T60 D131 E156 T157 K186 D190 H301 L347 M351 G352 H353 M358 F362 H51 T53 E55 T56 D127 E152 T153 K182 D186 H297 L343 M347 G348 H349 M354 F358 3.3.1.1 P23526 LPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQNHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVACAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 4pgq A 2.30 BS06 1FZ A 1 G179 S180 R183 S188 G189 D190 D192 Y271 F272 D276 G171 S172 R175 S180 G181 D182 D184 Y260 F261 D265 2.7.7.7,4.2.99.- P06746 25200079 ETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4pkb A 2.09 BS01 MAY A 1 G36 G37 G38 S77 T78 A188 D215 M331 G12 G13 G14 S53 T54 A164 D191 M307 3.1.1.- Q8LPW4 25248161 LGEMVTVLSIDGGGIRGIIPATILEFLEGQLQEMDNNADARLADYFDVIGGTSTGGLLTAMISTPNENNRPFAAAKEIVPFYFEHGPQIFNPSGQILGPKYDGKYLMQVLQEKLGETRVHQALTEVVISSFDIKTNKPVIFTKSNLANSPELDAKMYDISYSTAAAPTYFPPHYFVTNTSNGDEYEFNLVDGAVATVADPALLSISVATRLAQKDPAFASIRSLNYKKMLLLSLGTGTTSEFDKTYTAKEAATWTAVHWMLVIQKMTDAASSYMTDYYLSTAFQALDSKNNYLRVQENALTGTTTEMDDASEANMELLVQVGENLLKKPVSEDNPETYEEALKRFAKLLSDRKKLRA 4qar B 1.45 BS01 ADE B 1 F72 A73 G74 V120 Y124 V135 D136 M137 D161 F72 A73 G74 V113 Y117 V128 D129 M130 D154 B0B7H9 MFKLLLIFADPAEAARTLSLFPFSLNKENFYTYHTENVLLDVMVLKTWGYRGVVQALSPPPSGYDLWINAGFAGAANPNIPLLKTYTITSVKELTELEVTPIPRLPLAQLTSVRSPYRDGFHEHLQLVDMEGFFIAKQASLVACPCSMIKVSSDYTTREGQDFLKNNKVKLSQKLAEAIFPIYSSFI 4qat B 1.75 BS01 MTA B 1 A9 W48 F72 G74 V120 P123 Y124 D136 M137 E138 N161 T163 L171 A9 W48 F72 G74 V115 P118 Y119 D131 M132 E133 N156 T158 L166 B0B7H9 MFKLLLIFADPAEAARTLSLFPFSLNKENFYTYHTENVLLDVMVLKTWGYRGVVQALSPPPSGYDLWINAGFAGAANPNIPLLKTYTITSVKELTPEELEVTPIPRLPLAQLTSVRSPYRDGFHEHLQLVDMEGFFIAKQASLVACPCSMIKVSSNYTTREGQDFLKNNKVKLSQKLAEAIFPIYSSFI 4qjs D 2.90 BS01 NUC A 1 K7 P8 Y9 T10 S12 R13 R14 F15 F21 E28 K31 K35 P36 L37 K38 K39 T40 G42 R43 N44 N45 Q46 G47 R48 I49 T50 V51 R52 R54 G56 H58 K59 R60 L61 Y62 R63 Y84 P86 N87 R88 V98 D99 G100 E101 K102 E148 P149 K150 K151 K154 L155 A156 R157 A158 A159 G160 T161 Y172 L177 P178 S179 E181 R183 A199 H201 K202 V205 L206 G207 K208 A209 G210 R211 S212 R213 W214 R218 P219 H220 V221 R222 G223 A224 A225 M226 N227 P228 V229 D230 H231 H233 G235 G236 E237 G238 R239 A240 P241 R242 G243 R244 P245 P246 A247 S248 P249 W250 W252 Q253 T254 K255 G256 L257 K258 T259 R260 K261 R263 K264 S266 R268 F269 I270 R273 R274 K6 P7 Y8 T9 S11 R12 R13 F14 F20 E27 K30 K34 P35 L36 K37 K38 T39 G41 R42 N43 N44 Q45 G46 R47 I48 T49 V50 R51 R53 G55 H57 K58 R59 L60 Y61 R62 Y83 P85 N86 R87 V97 D98 G99 E100 K101 E147 P148 K149 K150 K153 L154 A155 R156 A157 A158 G159 T160 Y171 L176 P177 S178 E180 R182 A198 H200 K201 V204 L205 G206 K207 A208 G209 R210 S211 R212 W213 R217 P218 H219 V220 R221 G222 A223 A224 M225 N226 P227 V228 D229 H230 H232 G234 G235 E236 G237 R238 A239 P240 R241 G242 R243 P244 P245 A246 S247 P248 W249 W251 Q252 T253 K254 G255 L256 K257 T258 R259 K260 R262 K263 S265 R267 F268 I269 R272 R273 P60405 25104389 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIARRKK 4qjs D 2.90 BS02 MG D 1 F21 E23 I24 R91 F20 E22 I23 R90 P60405 25104389 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIARRKK 4qjs E 2.90 BS01 NUC A 1 K8 M11 T12 R13 P22 Q35 R37 K41 D42 Y44 Q48 Q54 K57 R58 N60 R61 P62 L63 G65 H66 K69 R76 I77 L78 R79 E80 R82 K109 G110 R111 G112 F113 A114 G115 K118 R119 N121 F122 A123 D127 S128 H129 G130 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 G148 R149 V150 Y151 K152 G153 K154 M156 A157 H159 Y160 R164 T166 M168 N169 L170 K185 G186 A187 P189 G190 P191 N192 K202 K203 A204 K8 M11 T12 R13 P22 Q35 R37 K41 D42 Y44 Q48 Q54 K57 R58 N60 R61 P62 L63 G65 H66 K69 R76 I77 L78 R79 E80 R82 K109 G110 R111 G112 F113 A114 G115 K118 R119 N121 F122 A123 D127 S128 H129 G130 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 G148 R149 V150 Y151 K152 G153 K154 M156 A157 H159 Y160 R164 T166 M168 N169 L170 K185 G186 A187 P189 G190 P191 N192 K202 K203 A204 Q5SHN8 25104389 MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLGFLPQNPKRVNRPLKGHFAKAGVEPVRILREIRDFNPEGDTVTVEIFKPGERVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNRKTPGRVYKGKKMAGHYGAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRETKKA 4qjs F 2.90 BS01 NUC A 1 N29 H31 L32 E35 R38 Q40 L41 A42 K43 R44 R45 R46 T48 A49 S50 T51 K52 T53 R54 G55 V57 A58 Y59 S60 G61 R62 K63 Q67 K68 H69 G71 R72 A73 R74 H75 G76 P81 I82 F83 V84 G85 V88 V89 F90 P92 P94 R95 Y99 T100 P102 K103 K104 V105 R106 K108 G134 K135 T136 K137 L140 R165 R168 N169 L170 G180 N182 Y184 R205 N24 H26 L27 E30 R33 Q35 L36 A37 K38 R39 R40 R41 T43 A44 S45 T46 K47 T48 R49 G50 V52 A53 Y54 S55 G56 R57 K58 Q62 K63 H64 G66 R67 A68 R69 H70 G71 P76 I77 F78 V79 G80 V83 V84 F85 P87 P89 R90 Y94 T95 P97 K98 K99 V100 R101 K103 G129 K130 T131 K132 L135 R160 R163 N164 L165 G175 N177 Y179 R200 Q5SHN9 25104389 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 4qjs F 2.90 BS03 MG F 2 Q67 K68 H69 T70 G71 R72 Q62 K63 H64 T65 G66 R67 Q5SHN9 25104389 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 4qjs G 2.90 BS01 NUC A 1 K36 V38 N40 G42 L43 E45 K47 T71 R72 A73 K74 I77 N79 F80 L82 I88 N123 S124 F125 D126 R128 N130 N132 L133 G134 L135 G154 D156 V160 K35 V37 N39 G41 L42 E44 K46 T70 R71 A72 K73 I76 N78 F79 L81 I87 N122 S123 F124 D125 R127 N129 N131 L132 G133 L134 G153 D155 V159 Q5SHQ0 25104389 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4qjs G 2.90 BS02 NUC B 1 P2 N27 W29 E30 Q66 K67 P68 A69 V70 R72 R91 V92 T93 R95 R98 P1 N26 W28 E29 Q65 K66 P67 A68 V69 R71 R90 V91 T92 R94 R97 Q5SHQ0 25104389 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4qjs G 2.90 BS03 MG G 1 R128 N130 T161 A163 E164 R127 N129 T160 A162 E163 Q5SHQ0 25104389 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4qjs H 2.90 BS01 NUC A 1 S2 R3 I4 R6 R59 K62 S63 G66 L67 T70 N74 G108 F109 S110 H111 K138 Q139 G142 Q143 R152 A156 Y157 H158 K160 K172 G174 K175 S1 R2 I3 R5 R58 K61 S62 G65 L66 T69 N73 G107 F108 S109 H110 K137 Q138 G141 Q142 R151 A155 Y156 H157 K159 K171 G173 K174 Q5SHQ3 25104389 SRIGRLPIPVPKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRLKPGK 4qjs J 2.90 BS01 NUC A 1 K4 R5 N6 G31 A34 H38 A54 K55 N56 L58 I59 L61 V80 V81 K1 R2 N3 G28 A31 H35 A51 K52 N53 L55 I56 L58 V77 V78 Q8VVE3 25104389 KRNVELLATLKENLERAQGSFFLVNYQGLPAKETHALRQALKQNGARLFVAKNTLIRLALKELGLPELDGLQGPSAVVFYEDPVAAAKTLVQFAKSNPKGIPQVKSGLLQGQILTAKDVEALAELPTMDE 4qjs K 2.90 BS01 NUC A 1 Q11 I52 P73 A74 S75 K86 G87 H89 K90 P91 L115 N116 T117 A122 R125 M126 G129 S130 R132 S133 M134 Q10 I51 P72 A73 S74 K85 G86 H88 K89 P90 L114 N115 T116 A121 R124 M125 G128 S129 R131 S132 M133 Q5SLP6 25104389 KKVVAVVKLQLPAGKATPAPPVGPALGQHGANIMEFVKAFNAATANMGDAIVPVEITIYADRSFTFVTKTPPASYLIRKAAGLEKGAHKPGREKVGRITWEQVLEIAKQKMPDLNTTDLEAAARMIAGSARSMGVEVVG 4qjs N 2.90 BS01 NUC A 1 K2 T3 V5 W13 T22 L23 G24 R25 T28 A31 T32 R35 K37 N45 F51 T63 K65 K66 Q69 K70 Y72 T73 R74 Y75 S76 Y78 P79 G80 G81 L82 K83 K89 H94 R97 E100 H101 A102 G105 M106 P108 K109 G110 P111 L112 R114 F117 K118 K121 P129 H130 Q133 K2 T3 V5 W13 T22 L23 G24 R25 T28 A31 T32 R35 K37 N45 F51 T63 K65 K66 Q69 K70 Y72 T73 R74 Y75 S76 Y78 P79 G80 G81 L82 K83 K89 H94 R97 E100 H101 A102 G105 M106 P108 K109 G110 P111 L112 R114 F117 K118 K121 P129 H130 Q133 P60488 25104389 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKLEV 4qjs O 2.90 BS01 NUC A 1 M1 Q3 Q5 T6 Y7 I22 R23 L25 K26 S28 N29 A30 K31 Y32 V40 S42 K44 G55 K59 K66 K67 E68 K70 R78 N82 M1 Q3 Q5 T6 Y7 I22 R23 L25 K26 S28 N29 A30 K31 Y32 V40 S42 K44 G55 K59 K66 K67 E68 K70 R78 N82 Q5SHP8 25104389 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 4qjs P 2.90 BS01 NUC A 1 L3 S4 R7 P8 N9 G11 A12 N13 K14 R15 R16 K17 R18 V19 G20 R21 G22 P23 G24 S25 G28 K29 T30 A31 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 L45 K46 R49 R50 F51 E52 G53 G54 R55 S56 T58 M60 R61 L62 P63 K64 R65 G66 M67 Q70 V71 P72 G73 E74 I75 R77 N84 R90 A103 G104 L105 K107 K108 K113 L115 G116 E117 S131 K132 L3 S4 R7 P8 N9 G11 A12 N13 K14 R15 R16 K17 R18 V19 G20 R21 G22 P23 G24 S25 G28 K29 T30 A31 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 L45 K46 R49 R50 F51 E52 G53 G54 R55 S56 T58 M60 R61 L62 P63 K64 R65 G66 M67 Q70 V71 P72 G73 E74 I75 R77 N84 R90 A103 G104 L105 K107 K108 K113 L115 G116 E117 S131 K132 Q5SHQ7 25104389 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLE 4qjs Q 2.90 BS01 NUC A 1 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 K18 K22 G23 G24 Y26 F29 A40 W41 Q46 A49 V52 R56 R59 R60 K63 R67 F69 D71 Y74 K76 K77 L79 E80 R82 M83 G84 K85 G86 K87 G88 R101 R119 H123 K124 L125 P126 K128 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 K18 K22 G23 G24 Y26 F29 A40 W41 Q46 A49 V52 R56 R59 R60 K63 R67 F69 D71 Y74 K76 K77 L79 E80 R82 M83 G84 K85 G86 K87 G88 R101 R119 H123 K124 L125 P126 K128 P60489 25104389 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4qjs Q 2.90 BS03 MG Q 1 T75 K76 K77 G88 T75 K76 K77 G88 P60489 25104389 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4qjs R 2.90 BS01 NUC A 1 M1 R2 H3 L4 K5 S6 R8 K9 L10 N11 R12 H13 S14 S15 H16 R17 A19 L20 R22 N23 Q24 K26 S27 H31 I34 T35 T36 T37 P39 K40 K42 R45 G46 D49 H50 H53 R57 L60 H61 R63 R64 L67 R68 Q71 R77 R90 Q91 G92 G93 T95 R96 K99 R104 R105 G106 D107 A109 M1 R2 H3 L4 K5 S6 R8 K9 L10 N11 R12 H13 S14 S15 H16 R17 A19 L20 R22 N23 Q24 K26 S27 H31 I34 T35 T36 T37 P39 K40 K42 R45 G46 D49 H50 H53 R57 L60 H61 R63 R64 L67 R68 Q71 R77 R90 Q91 G92 G93 T95 R96 K99 R104 R105 G106 D107 A109 Q9Z9H5 25104389 MRHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE 4qjs R 2.90 BS02 MG R 1 V97 L98 K99 V97 L98 K99 Q9Z9H5 25104389 MRHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE 4qjs S 2.90 BS01 NUC A 1 R3 L4 A6 R9 R10 F12 R13 V14 N16 R17 I18 T21 R23 A86 F87 R89 Y94 R106 F112 R1 L2 A4 R7 R8 F10 R11 V12 N14 R15 I16 T19 R21 A84 F85 R87 Y92 R104 F110 Q5SHQ4 25104389 RLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 4qjs S 2.90 BS02 NUC B 1 R10 K11 R15 K19 R25 F29 R30 S31 L32 K33 Y36 Q38 V46 T47 S50 S52 L54 A55 K57 N61 K62 T63 Y92 K93 H95 R97 R8 K9 R13 K17 R23 F27 R28 S29 L30 K31 Y34 Q36 V44 T45 S48 S50 L52 A53 K55 N59 K60 T61 Y90 K91 H93 R95 Q5SHQ4 25104389 RLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 4qjs T 2.90 BS01 NUC A 1 N2 R3 G4 R23 R51 R53 R54 N55 G56 N58 T60 R93 R95 R96 A97 K98 Y100 F101 K113 K119 N2 R3 G4 R23 R51 R53 R54 N55 G56 N58 T60 R93 R95 R96 A97 K98 Y100 F101 K113 K119 P60490 25104389 MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVIRIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLYFIRNLSDREIRRKLRADRKRIDQDRAAERAA 4qjs U 2.90 BS01 NUC A 1 P2 R3 A4 K5 T6 G7 V8 R10 R11 R12 K13 H14 K15 K16 K19 G23 Y24 W25 G26 L27 R28 K30 S31 F32 R33 K34 R36 E37 F40 A41 A42 Y45 A46 Y47 H49 R50 K51 R52 R53 K54 R55 F57 R58 R59 W61 V63 N66 R70 N75 Y76 S77 H81 K84 D91 R92 K93 P1 R2 A3 K4 T5 G6 V7 R9 R10 R11 K12 H13 K14 K15 K18 G22 Y23 W24 G25 L26 R27 K29 S30 F31 R32 K33 R35 E36 F39 A40 A41 Y44 A45 Y46 H48 R49 K50 R51 R52 K53 R54 F56 R57 R58 W60 V62 N65 R69 N74 Y75 S76 H80 K83 D90 R91 K92 P60491 25104389 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQ 4qjs U 2.90 BS02 MG U 1 A46 R50 A45 R49 P60491 25104389 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQ 4qjs V 2.90 BS01 NUC A 1 G8 G9 K10 K19 E23 K24 R66 K69 V72 K74 F75 K76 A77 K78 V79 Q80 Y81 R82 R83 K84 K85 G86 H87 R88 Q89 P90 G8 G9 K10 K19 E23 K24 R66 K69 V72 K74 F75 K76 A77 K78 V79 Q80 Y81 R82 R83 K84 K85 G86 H87 R88 Q89 P90 P60492 25104389 MFAIVKTGGKQYRVEPGLKLRVEKLDAEPGATVELPVLLLGGEKTVVGTPVVEGASVVAEVLGHGRGKKILVSKFKAKVQYRRKKGHRQPYTELLIKEIRG 4qjs W 2.90 BS01 NUC A 1 K4 A5 I6 A7 R8 Y9 R11 S13 R15 K16 R18 R25 N40 K41 R42 Y45 K49 S53 A56 N57 N60 N61 H62 Y75 D77 E78 P80 K83 R84 P87 R88 A89 R90 G91 R92 A93 D94 I96 K97 K98 R99 H102 K4 A5 I6 A7 R8 Y9 R11 S13 R15 K16 R18 R25 N40 K41 R42 Y45 K49 S53 A56 N57 N60 N61 H62 Y75 D77 E78 P80 K83 R84 P87 R88 A89 R90 G91 R92 A93 D94 I96 K97 K98 R99 H102 Q5SHP3 25104389 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHG 4qjs W 2.90 BS02 MG W 1 A55 E66 A55 E66 Q5SHP3 25104389 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHG 4qjs X 2.90 BS01 NUC A 1 M1 K2 S14 K16 K25 H31 K33 T35 K36 T37 K40 N41 E44 K53 N55 T56 L57 H58 R60 K62 K63 K64 R65 L66 R68 Y69 L70 G71 K72 R73 P74 D75 K77 K78 I80 M1 K2 S14 K16 K25 H31 K33 T35 K36 T37 K40 N41 E44 K53 N55 T56 L57 H58 R60 K62 K63 K64 R65 L66 R68 Y69 L70 G71 K72 R73 P74 D75 K77 K78 I80 Q5SHP0 25104389 MKTAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEGL 4qjs Y 2.90 BS01 NUC A 1 M1 K4 M5 H6 K8 K9 S17 G18 K19 V30 P32 Y35 K46 K47 A48 V49 R50 V51 G59 F60 K63 H68 S70 K71 R73 R84 R86 K87 K95 K101 M1 K4 M5 H6 K8 K9 S17 G18 K19 V30 P32 Y35 K46 K47 A48 V49 R50 V51 G59 F60 K63 H68 S70 K71 R73 R84 R86 K87 K95 K101 Q5SHP9 25104389 MRVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCGGALD 4qjs Z 2.90 BS01 NUC A 1 K46 Q118 I120 I146 S149 H151 E169 T170 P176 K46 Q118 I120 I146 S149 H151 E169 T170 P176 Q5SHZ1 25104389 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKLAE 4qjs Z 2.90 BS02 NUC B 1 R10 P15 R19 G26 V27 Y29 N30 R31 N34 K36 R72 Q73 N75 R79 R80 E84 H85 F89 R10 P15 R19 G26 V27 Y29 N30 R31 N34 K36 R72 Q73 N75 R79 R80 E84 H85 F89 Q5SHZ1 25104389 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKLAE 4qjs 0 2.90 BS01 NUC A 1 R11 N12 R14 D15 S16 Q17 A18 K19 R20 V23 K24 R25 Y26 E27 Q29 R32 A33 N35 I36 R39 R41 G42 T43 R44 G54 R55 D56 F57 F60 L62 F69 R74 R77 R1 N2 R4 D5 S6 Q7 A8 K9 R10 V13 K14 R15 Y16 E17 Q19 R22 A23 N25 I26 R29 R31 G32 T33 R34 G44 R45 D46 F47 F50 L52 F59 R64 R67 P60493 25104389 RNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPL 4qjs 0 2.90 BS02 NUC B 1 Q70 R72 G73 R74 Q60 R62 G63 R64 P60493 25104389 RNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPL 4qjs 0 2.90 BS03 MG 0 1 E27 E68 E17 E58 P60493 25104389 RNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPL 4qjs 1 2.90 BS01 NUC A 1 S2 K3 K10 R11 I13 V14 A15 N16 I18 Q19 R20 R21 A24 K25 R26 G28 G29 V30 G31 K32 K33 T34 T35 I37 S38 K39 R40 R41 Q42 Y43 P44 N45 Q47 K48 R50 R52 G55 R61 S65 H66 P68 K69 R76 G79 K92 S1 K2 K9 R10 I12 V13 A14 N15 I17 Q18 R19 R20 A23 K24 R25 G27 G28 V29 G30 K31 K32 T33 T34 I36 S37 K38 R39 R40 Q41 Y42 P43 N44 Q46 K47 R49 R51 G54 R60 S64 H65 P67 K68 R75 G78 K91 P60494 25104389 SKVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELLKLL 4qjs 2 2.90 BS01 NUC A 1 K2 L3 R7 L10 R14 K29 S45 Q46 N47 H48 R51 K54 R55 A58 R59 L61 T62 N65 E66 K2 L3 R7 L10 R14 K29 S45 Q46 N47 H48 R51 K54 R55 A58 R59 L61 T62 N65 E66 Q5SHP6 25104389 MKLSEVRKQLEEARKLSPVELEKLVREKKRELMELRFQASIGQLSQNHKIRDLKRQIARLLTVLNEKRRQ 4qjs 3 2.90 BS01 NUC A 1 K10 S11 I13 G14 Y15 P16 K17 D18 K20 A21 A22 K24 A25 R29 R30 L31 P41 A42 G45 N46 K49 K9 S10 I12 G13 Y14 P15 K16 D17 K19 A20 A21 K23 A24 R28 R29 L30 P40 A41 G44 N45 K48 Q5SHQ6 25104389 PRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVAHLVRVEVVE 4qjs 5 2.90 BS01 NUC A 1 A2 K3 H4 P5 V6 P7 K8 K9 K10 T11 S12 K13 A14 R15 R16 D17 A18 R19 R20 S21 H22 H23 A24 T29 V31 P32 P34 P42 H43 Y52 A53 A1 K2 H3 P4 V5 P6 K7 K8 K9 T10 S11 K12 A13 R14 R15 D16 A17 R18 R19 S20 H21 H22 A23 T28 V30 P31 P33 P41 H42 Y51 A52 P80339 25104389 AKHPVPKKKTSKARRDARRSHHALTPPTLVPCPECKAMKPPHTVCPECGYYAGRKVLEV 4qjs 6 2.90 BS01 NUC A 1 A2 S3 R6 K8 R18 R19 Y21 A22 E24 N26 N29 T30 L34 L36 R37 K38 Y39 P41 W42 R44 H46 I54 A1 S2 R5 K7 R17 R18 Y20 A21 E23 N25 N28 T29 L33 L35 R36 K37 Y38 P40 W41 R43 H45 I53 P35871 25104389 ASEVRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVKI 4qjs 7 2.90 BS01 NUC A 1 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 T15 H16 G17 F18 R19 R21 M22 R23 P25 G27 R28 K29 V30 K32 R33 R34 R35 K37 G38 R39 W40 R41 R47 K48 R49 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 T15 H16 G17 F18 R19 R21 M22 R23 P25 G27 R28 K29 V30 K32 R33 R34 R35 K37 G38 R39 W40 R41 R47 K48 R49 P80340 25104389 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRKR 4qjs 7 2.90 BS02 MG 7 1 H16 R21 L42 P44 H16 R21 L42 P44 P80340 25104389 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRKR 4qjs 7 2.90 BS03 MG 7 2 A13 K14 R19 A20 A13 K14 R19 A20 P80340 25104389 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRKR 4qjs 8 2.90 BS01 NUC A 1 P2 K3 M4 K5 T6 H7 K8 K11 K12 R13 K15 T17 A18 S19 K21 K26 T27 G28 K29 R30 H31 L32 N33 W34 Q35 S37 K39 I41 R42 Q43 K44 K47 V49 A51 K52 P53 E54 Y64 P1 K2 M3 K4 T5 H6 K7 K10 K11 R12 K14 T16 A17 S18 K20 K25 T26 G27 K28 R29 H30 L31 N32 W33 Q34 S36 K38 I40 R41 Q42 K43 K46 V48 A50 K51 P52 E53 Y63 Q5SKU1 25104389 PKMKTHKGAKKRVKITASGKVVAMKTGKRHLNWQKSGKEIRQKGRKFVLAKPEAERIKLLLPYE 4qjs 9 2.90 BS01 NUC A 1 M1 K2 R4 A5 S6 V7 K8 I10 D12 K15 V16 I17 R18 R19 H20 G21 R22 V23 Y24 P30 K31 K33 R35 Q36 G37 M1 K2 R4 A5 S6 V7 K8 I10 D12 K15 V16 I17 R18 R19 H20 G21 R22 V23 Y24 P30 K31 K33 R35 Q36 G37 Q5SHR2 25104389 MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG 4qjt b 2.90 BS01 NUC a 1 K22 W24 P26 K27 R96 G99 G100 T103 N104 R111 K133 R144 Y148 R175 K179 K16 W18 P20 K21 R90 G93 G94 T97 N98 R105 K127 R138 Y142 R169 K173 P80371 25104389 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYA 4qjt c 2.90 BS01 NUC a 1 G2 N3 K4 I5 F10 I14 K26 R127 S154 G155 R156 E161 Q162 A163 W167 R172 V173 P174 L175 H176 T177 L178 R179 F186 T192 G194 V195 G197 K199 G1 N2 K3 I4 F9 I13 K25 R126 S153 G154 R155 E160 Q161 A162 W166 R171 V172 P173 L174 H175 T176 L177 R178 F185 T191 G193 V194 G196 K198 P80372 25104389 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEV 4qjt d 2.90 BS01 NUC a 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 G23 E24 R25 K30 R35 R36 Y38 P40 G41 Q42 H43 Q45 K46 S52 Y54 A55 R59 K61 Q62 R65 R66 E72 R73 Q74 R76 N77 V112 S113 R115 Q116 R118 Q119 R122 H123 H125 R132 V133 D134 L135 P136 S137 E150 L155 E156 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 G22 E23 R24 K29 R34 R35 Y37 P39 G40 Q41 H42 Q44 K45 S51 Y53 A54 R58 K60 Q61 R64 R65 E71 R72 Q73 R75 N76 V111 S112 R114 Q115 R117 Q118 R121 H122 H124 R131 V132 D133 L134 P135 S136 E149 L154 E155 E204 S207 R208 P80373 25104389 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4qjt d 2.90 BS02 SF4 d 1 V8 C9 C12 K18 L19 K22 C26 C31 A32 M33 V7 C8 C11 K17 L18 K21 C25 C30 A31 M32 P80373 25104389 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4qjt e 2.90 BS01 NUC a 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 K47 P49 K57 Y61 R64 F84 A86 K92 A94 A95 T98 A102 G103 L119 T120 K121 E122 L123 S125 R126 N127 I129 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 K43 P45 K53 Y57 R60 F80 A82 K88 A90 A91 T94 A98 G99 L115 T116 K117 E118 L119 S121 R122 N123 I125 N126 Y129 Q5SHQ5 25104389 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLR 4qjt f 2.90 BS01 NUC a 1 R2 Y4 Y50 K54 N73 R80 R87 V90 K92 R2 Y4 Y50 K54 N73 R80 R87 V90 K92 Q5SLP8 25104389 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLAN 4qjt g 2.90 BS01 NUC x 1 S77 N84 Q86 D140 R143 M144 S76 N83 Q85 D139 R142 M143 P17291 25104389 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4qjt g 2.90 BS02 NUC a 1 A2 R3 R4 R6 R10 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 I42 R76 R79 Y85 R94 R95 S98 R102 N109 R114 R115 A116 R119 A1 R2 R3 R5 R9 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 I41 R75 R78 Y84 R93 R94 S97 R101 N108 R113 R114 A115 R118 P17291 25104389 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4qjt h 2.90 BS01 NUC a 1 L2 T3 D4 A7 D8 T11 R12 R14 N15 V19 K21 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 V95 G96 V97 R105 S113 T114 S115 V118 G128 V129 G130 G131 E132 L1 T2 D3 A6 D7 T10 R11 R13 N14 V18 K20 S28 R29 F30 K55 R74 K87 P88 G89 R90 R91 Y93 V94 G95 V96 R104 S112 T113 S114 V117 G127 V128 G129 G130 E131 Q5SHQ2 25104389 LTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4qjt i 2.90 BS01 NUC a 1 Q3 Y5 T7 R9 K11 E12 V14 R16 R20 Y36 Q38 R42 Y62 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 A106 R107 V108 V109 E110 R111 K112 K113 Y114 G115 H117 K118 R120 R121 A122 Q124 Y125 S126 K127 R128 Q2 Y4 T6 R8 K10 E11 V13 R15 R19 Y35 Q37 R41 Y61 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 A105 R106 V107 V108 E109 R110 K111 K112 Y113 G114 H116 K117 R119 R120 A121 Q123 Y124 S125 K126 R127 P80374 25104389 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4qjt j 2.90 BS01 NUC a 1 R5 K7 H13 D17 S35 G36 P37 I38 P39 L40 P41 T42 R43 V44 R45 T48 R51 G52 P53 F54 K55 H56 K57 S59 R60 H62 H68 R70 D73 E97 R1 K3 H9 D13 S31 G32 P33 I34 P35 L36 P37 T38 R39 V40 R41 T44 R47 G48 P49 F50 K51 H52 K53 S55 R56 H58 H64 R66 D69 E93 Q5SHN7 25104389 RIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT 4qjt k 2.90 BS01 NUC a 1 Y20 N26 N27 I29 T31 G37 N38 P39 W42 S44 G46 G52 S53 K55 R85 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 R126 Y8 N14 N15 I17 T19 G25 N26 P27 W30 S32 G34 G40 S41 K43 R73 V102 P103 H104 N105 G106 C107 R108 P109 K110 K111 R114 P80376 25104389 QVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFR 4qjt l 2.90 BS01 NUC a 1 P5 T6 N8 Q9 L10 R12 K13 R15 E16 K23 V24 L27 G29 A30 P31 F32 R33 R34 K46 K47 P48 N49 S50 A51 L52 R53 K54 T61 Y69 G72 E73 G74 G87 R89 V90 K91 D92 R97 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 K9 R11 E12 K19 V20 L23 G25 A26 P27 F28 R29 R30 K42 K43 P44 N45 S46 A47 L48 R49 K50 T57 Y65 G68 E69 G70 G83 R85 V86 K87 D88 R93 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 Q5SHN3 25104389 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPK 4qjt l 2.90 BS02 MG l 1 K114 K115 S116 R117 K110 K111 S112 R113 Q5SHN3 25104389 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPK 4qjt m 2.90 BS01 NUC a 1 K13 R14 V17 Y21 I22 Y23 G24 I25 G26 A28 R29 R44 L70 N77 I78 Y87 R88 R91 H92 L96 P97 V98 R99 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 R114 K115 T116 V117 K12 R13 V16 Y20 I21 Y22 G23 I24 G25 A27 R28 R43 L69 N76 I77 Y86 R87 R90 H91 L95 P96 V97 R98 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 R113 K114 T115 V116 P80377 25104389 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGK 4qjt o 2.90 BS01 NUC a 1 P2 K5 K8 Q9 F18 D21 T22 G23 S24 Q28 L31 R35 R38 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 M58 M59 Q62 R64 R65 L66 R68 Y69 R72 P1 K4 K7 Q8 F17 D20 T21 G22 S23 Q27 L30 R34 R37 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 M57 M58 Q61 R63 R64 L65 R67 Y68 R71 Q5SJ76 25104389 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 4qjt p 2.90 BS01 NUC a 1 M1 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 H16 Y17 R18 D23 R25 R26 K27 R28 D29 G30 K31 K35 Y38 P41 R42 K43 T44 Y58 W59 S61 V62 G63 Q65 T67 T69 R72 R75 F80 R81 Q82 M1 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 H16 Y17 R18 D23 R25 R26 K27 R28 D29 G30 K31 K35 Y38 P41 R42 K43 T44 Y58 W59 S61 V62 G63 Q65 T67 T69 R72 R75 F80 R81 Q82 Q5SJH3 25104389 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQ 4qjt q 2.90 BS01 NUC a 1 P2 S12 K14 M15 Q16 K17 T18 T20 R25 L31 Y32 K34 K37 R38 S39 K40 K41 Y42 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 R72 K87 I90 R91 R92 N94 Y95 S97 L98 S99 K100 P1 S11 K13 M14 Q15 K16 T17 T19 R24 L30 Y31 K33 K36 R37 S38 K39 K40 Y41 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 R71 K86 I89 R90 R91 N93 Y94 S96 L97 S98 K99 Q5SHP7 25104389 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSK 4qjt s 2.90 BS01 NUC a 1 P2 R3 S4 L5 K6 K7 F10 H14 K18 W34 R36 R37 Y52 N53 G54 K55 K70 G72 T77 R78 T79 Y80 H83 P1 R2 S3 L4 K5 K6 F9 H13 K17 W33 R35 R36 Y51 N52 G53 K54 K69 G71 T76 R77 T78 Y79 H82 Q5SHP2 25104389 PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYRGHG 4qjt t 2.90 BS01 NUC a 1 R8 L10 S11 K14 R15 H16 R17 Q18 K21 R22 R23 L24 N26 A28 K29 S31 A32 K34 T35 L36 K39 E51 R57 E60 S61 D64 K68 S70 H73 N75 A78 R79 R80 K81 S82 R83 M85 R89 I100 G101 G102 G103 R1 L3 S4 K7 R8 H9 R10 Q11 K14 R15 R16 L17 N19 A21 K22 S24 A25 K27 T28 L29 K32 E44 R50 E53 S54 D57 K61 S63 H66 N68 A71 R72 R73 K74 S75 R76 M78 R82 I93 G94 G95 G96 P80380 25104389 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGG 4qjt y 2.90 BS01 NUC w 1 Y563 G564 D566 T568 R569 K571 K572 E575 Y605 G606 D608 T610 R611 K613 K614 E617 Q5SKA7 25104389 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLSRIRNFSIIAHVDHGKSTLADRILELTHSAVRVTYRAKDGEEYVFHLIDTPGHVDFTYEVSRALAAVEGVLLVVDASQGVEAETLAKFYMALEHGHVIIPVINKIDLPNARPLEVALEVEEVLGLPADEAIFASGKTGEGVEEILEAIVQRIPPPKGDPEAPLKALIFDSVYDAYQGVIPYLRLFEGRVRPGDRIRIYSTGKEFTVDKVGVFTPQGLVATEALEAGEVGWLVAAIRDIHDVQVGDTITLADRPTPSPYPGFRPAKPVVFAGLYPVDSGDYGKLRDALEKLKLNDAALTFEPESSTALGFGFRCGFLGLLHAEIVQERLEREFGLSLIATAPSVVYKVRLKSGEEVEVHNPADLPDPTRIEEILEPYVKLTIFTPEEYVGSLMQLLQEKRGRLVNMNYLPGAQKRVELVYEAPFAEILYDFHDRLKSVSRGYASMDYEQAGYRPGDLVKVNVLVHGEVVDALTFIAHREKAYTMARAIVDKLAEVIPRQLFEVPIQAAIGGKIIARATVKALRKDVLAKCYGGDVTRKKKLLEKQKEGKKRLKAIGKVEVPQEAFLAVLS 4qjt y 2.90 BS02 MG y 1 V18 H86 V87 H128 Q5SKA7 25104389 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLSRIRNFSIIAHVDHGKSTLADRILELTHSAVRVTYRAKDGEEYVFHLIDTPGHVDFTYEVSRALAAVEGVLLVVDASQGVEAETLAKFYMALEHGHVIIPVINKIDLPNARPLEVALEVEEVLGLPADEAIFASGKTGEGVEEILEAIVQRIPPPKGDPEAPLKALIFDSVYDAYQGVIPYLRLFEGRVRPGDRIRIYSTGKEFTVDKVGVFTPQGLVATEALEAGEVGWLVAAIRDIHDVQVGDTITLADRPTPSPYPGFRPAKPVVFAGLYPVDSGDYGKLRDALEKLKLNDAALTFEPESSTALGFGFRCGFLGLLHAEIVQERLEREFGLSLIATAPSVVYKVRLKSGEEVEVHNPADLPDPTRIEEILEPYVKLTIFTPEEYVGSLMQLLQEKRGRLVNMNYLPGAQKRVELVYEAPFAEILYDFHDRLKSVSRGYASMDYEQAGYRPGDLVKVNVLVHGEVVDALTFIAHREKAYTMARAIVDKLAEVIPRQLFEVPIQAAIGGKIIARATVKALRKDVLAKCYGGDVTRKKKLLEKQKEGKKRLKAIGKVEVPQEAFLAVLS 4qjt y 2.90 BS03 GDP y 1 V18 D19 G21 K22 S23 T24 K137 L140 G168 K169 V87 D88 G90 K91 S92 T93 K179 L182 G210 K211 Q5SKA7 25104389 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLSRIRNFSIIAHVDHGKSTLADRILELTHSAVRVTYRAKDGEEYVFHLIDTPGHVDFTYEVSRALAAVEGVLLVVDASQGVEAETLAKFYMALEHGHVIIPVINKIDLPNARPLEVALEVEEVLGLPADEAIFASGKTGEGVEEILEAIVQRIPPPKGDPEAPLKALIFDSVYDAYQGVIPYLRLFEGRVRPGDRIRIYSTGKEFTVDKVGVFTPQGLVATEALEAGEVGWLVAAIRDIHDVQVGDTITLADRPTPSPYPGFRPAKPVVFAGLYPVDSGDYGKLRDALEKLKLNDAALTFEPESSTALGFGFRCGFLGLLHAEIVQERLEREFGLSLIATAPSVVYKVRLKSGEEVEVHNPADLPDPTRIEEILEPYVKLTIFTPEEYVGSLMQLLQEKRGRLVNMNYLPGAQKRVELVYEAPFAEILYDFHDRLKSVSRGYASMDYEQAGYRPGDLVKVNVLVHGEVVDALTFIAHREKAYTMARAIVDKLAEVIPRQLFEVPIQAAIGGKIIARATVKALRKDVLAKCYGGDVTRKKKLLEKQKEGKKRLKAIGKVEVPQEAFLAVLS 4qme A 1.60 BS01 37B A 1 M103 Q115 E117 P118 F254 N255 M256 G257 A258 M259 E260 S289 V290 H293 E294 H297 K315 E316 V320 D323 N369 Y372 Y377 E378 Q818 M102 Q114 E116 P117 F253 N254 M255 G256 A257 M258 E259 S288 V289 H292 E293 H296 K314 E315 V319 D322 N368 Y371 Y376 E377 Q817 3.4.11.2 Q9JYV4 25192493 SKTVHYLKDYQTPAYHILKTDLHFDINEPQTVVKSRLTVEPQRVGEPLVLDGSAKLLSVKINGAAADYVLEGETLTIAGVPSERFTVEVETEILPAENKSLMGLYASGGNLFTQCEPEGFRKITFYIDRPDVMSKFTTTIVADKKRYPVLLSNGNKIDGGEFSDGRHWVKWEDPFSKPSYLFALVAGDLAVTEDYFTTMSGRNVKIEFYTTEADKPKVGFAVESLKNAMKWDETRFGLEYDLDIFMVVAVGDFNMGAMENKGLNIFNTKFVLADSRTATDTDFEGIESVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSGDRASRAVRRIENIRLLRQHQFPEDAGPTAHPVRPASYEEMNNFYTMTVYEKGAEVVRMYHTLLGEEGFQKGMKLYFQRHDGQAVTCDDFRAAMADANGINLDQFALWYSQAGTPVLEAEGRLKNNIFELTVKQTVPPTPDMTDKQPMMIPVKVGLLNRNGEAVAFDYQGKRATEAVLLLTEAEQTFLLEGVTEAVVPSLLRGFSAPVHLNYPYSDDDLLLLLAHDSDAFTRWEAAQTLYRRAVAANLATLSDGVELPKHEKLLAAVEKVISDDLLDNAFKALLLGVPSEAELWDGAENIDPLRYHQAREALLDTLAVHFLPKWHELNRQAAKQENQSYEYSPEAAGWRTLRNVCRAFVLRADPAHIETVAEKYGEMAQNMTHEWGILSAVNGNESDTRNRLLAQFADKFSDDALVMDKYFALVGSSRRSDTLQQVRTALQHPKFSLENPNKARSLIGSFSRNVPHFHAEDGSGYRFIADKVIEIDRFNPQVAARLVQAFNLCNKLEPHRKNLVKQALQRIRAQEGLSKDVGEIVGKILD 4qs0 B 3.80 BS01 NUC A 1 K22 W24 R96 G99 T103 N104 T107 R111 K132 K133 R144 K179 K16 W18 R90 G93 T97 N98 T101 R105 K126 K127 R138 K173 P62662 25190797 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQE 4qs0 C 3.80 BS01 NUC A 1 G2 N3 K4 I5 F10 K27 R127 K150 S154 G155 R156 E161 Q162 A163 W167 R172 V173 P174 L175 H176 T177 L178 R179 F186 Y193 G194 V195 L196 G197 K199 G1 N2 K3 I4 F9 K26 R126 K149 S153 G154 R155 E160 Q161 A162 W166 R171 V172 P173 L174 H175 T176 L177 R178 F185 Y192 G193 V194 L195 G196 K198 P62663 25190797 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEVI 4qs0 C 3.80 BS02 NUC V 1 K72 G74 V75 F128 R131 R132 Q136 R140 A160 E161 K71 G73 V74 F127 R130 R131 Q135 R139 A159 E160 P62663 25190797 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEVI 4qs0 D 3.80 BS01 NUC A 1 G2 R3 Y4 I5 P7 V8 R10 R13 R14 K22 E24 R25 K30 A32 R35 R36 Y38 P40 G41 Q42 H43 Y54 Q62 R65 R66 S71 E72 R73 Q74 N77 K84 K85 K86 S113 R115 Q116 R118 Q119 R122 H123 H125 R131 R132 V133 D134 L135 S137 Y138 R141 K151 R209 G1 R2 Y3 I4 P6 V7 R9 R12 R13 K21 E23 R24 K29 A31 R34 R35 Y37 P39 G40 Q41 H42 Y53 Q61 R64 R65 S70 E71 R72 Q73 N76 K83 K84 K85 S112 R114 Q115 R117 Q118 R121 H122 H124 R130 R131 V132 D133 L134 S136 Y137 R140 K150 R208 P62664 25190797 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4qs0 E 3.80 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R25 R27 P49 K57 Y60 Y61 F84 G85 A86 S87 K92 T98 A102 G103 R107 L119 T120 K121 E122 L123 S125 R126 N127 I129 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R21 R23 P45 K53 Y56 Y57 F80 G81 A82 S83 K88 T94 A98 G99 R103 L115 T116 K117 E118 L119 S121 R122 N123 I125 N126 Y129 P62665 25190797 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKGE 4qs0 F 3.80 BS01 NUC A 1 Y4 K54 E69 V72 N73 R77 R80 R87 M89 V90 K92 Y4 K54 E69 V72 N73 R77 R80 R87 M89 V90 K92 P62666 25190797 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4qs0 G 3.80 BS01 NUC A 1 A2 R3 R4 R5 R6 A7 N28 K29 I30 M31 R32 D33 G34 K35 K36 L38 R41 R76 R79 R94 R95 S98 R102 E113 R114 A116 R119 W156 A1 R2 R3 R4 R5 A6 N27 K28 I29 M30 R31 D32 G33 K34 K35 L37 R40 R75 R78 R93 R94 S97 R101 E112 R113 A115 R118 W155 P62667 25190797 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4qs0 H 3.80 BS01 NUC A 1 M1 L2 T3 A7 D8 T11 R12 R14 N15 R18 V19 K21 S29 R30 F31 K56 R85 K88 P89 R91 R92 Y94 V95 G96 E99 R105 S113 T114 S115 G128 G130 G131 E132 M1 L2 T3 A7 D8 T11 R12 R14 N15 R18 V19 K21 S29 R30 F31 K56 R85 K88 P89 R91 R92 Y94 V95 G96 E99 R105 S113 T114 S115 G128 G130 G131 E132 P62668 25190797 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4qs0 I 3.80 BS01 NUC A 1 Y5 R9 K11 E12 R16 F18 R20 Y36 Q38 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 P98 L102 T103 R104 A106 R107 V108 V109 E110 R111 K112 K113 Y114 K116 H117 K118 R120 R121 P123 Q124 Y125 S126 R128 Y4 R8 K10 E11 R15 F17 R19 Y35 Q37 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 P97 L101 T102 R103 A105 R106 V107 V108 E109 R110 K111 K112 Y113 K115 H116 K117 R119 R120 P122 Q123 Y124 S125 R127 P62669 25190797 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4qs0 J 3.80 BS01 NUC A 1 R5 K7 D17 S35 G36 P39 L40 P41 R43 V44 R45 R46 F47 T48 R51 G52 P53 F54 K55 H56 K57 S59 R60 E61 H62 R66 H68 R70 D73 R3 K5 D15 S33 G34 P37 L38 P39 R41 V42 R43 R44 F45 T46 R49 G50 P51 F52 K53 H54 K55 S57 R58 E59 H60 R64 H66 R68 D71 P62653 25190797 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKTV 4qs0 K 3.80 BS01 NUC A 1 R12 Y20 N26 N27 I29 D36 G37 N38 P39 W42 G46 V47 K51 G52 S53 K55 R85 P113 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 K124 R2 Y10 N16 N17 I19 D26 G27 N28 P29 W32 G36 V37 K41 G42 S43 K45 R75 P103 V104 P105 H106 N107 G108 C109 R110 P111 K112 K113 K114 P62654 25190797 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS 4qs0 L 3.80 BS01 NUC A 1 P5 I7 N8 Q9 R12 R15 E16 K17 K20 K21 S22 V24 P25 K28 G29 P31 F32 R33 R34 T44 P45 K46 K47 P48 N49 S50 A51 L52 R53 T61 E65 Y69 P71 G72 E73 L84 R86 G87 R89 V90 K91 D92 P94 V101 R113 K114 K115 S116 R117 S118 K119 Y120 G121 K123 K124 P1 I3 N4 Q5 R8 R11 E12 K13 K16 K17 S18 V20 P21 K24 G25 P27 F28 R29 R30 T40 P41 K42 K43 P44 N45 S46 A47 L48 R49 T57 E61 Y65 P67 G68 E69 L80 R82 G83 R85 V86 K87 D88 P90 V97 R109 K110 K111 S112 R113 S114 K115 Y116 G117 K119 K120 P61941 25190797 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEAA 4qs0 M 3.80 BS01 NUC A 1 R14 V17 Y21 I22 Y23 G24 I25 G26 A28 R29 R44 V74 Y87 R88 R91 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 K111 P113 R114 K115 T116 V117 G119 K120 K121 K122 P124 R125 K126 R13 V16 Y20 I21 Y22 G23 I24 G25 A27 R28 R43 V73 Y86 R87 R90 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 K110 P112 R113 K114 T115 V116 G118 K119 K120 K121 P123 R124 K125 P62655 25190797 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKKAPRK 4qs0 M 3.80 BS03 NUC X 1 K120 K121 A123 P124 K126 K119 K120 A122 P123 K125 P62655 25190797 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKKAPRK 4qs0 N 3.80 BS01 NUC A 1 A2 R3 K4 A5 L6 K9 F16 K17 V18 R19 Y21 T22 C27 G28 R29 R31 S32 V33 Y34 R35 R41 I42 C43 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 K8 F15 K16 V17 R18 Y20 T21 C26 G27 R28 R30 S31 V32 Y33 R34 R40 I41 C42 R44 E45 K57 S59 W60 P62656 25190797 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4qs0 O 3.80 BS01 NUC A 1 K8 Q9 I12 F18 D21 T22 G23 S24 T25 Q28 R38 L39 H42 H46 K48 D49 H50 H51 S52 R54 L57 M58 M59 Q62 R64 R65 L66 R68 Y69 R72 K7 Q8 I11 F17 D20 T21 G22 S23 T24 Q27 R37 L38 H41 H45 K47 D48 H49 H50 S51 R53 L56 M57 M58 Q61 R63 R64 L65 R67 Y68 R71 P62657 25190797 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 4qs0 P 3.80 BS01 NUC A 1 M1 R5 F9 G10 S11 K12 H13 N14 H16 R18 R25 R26 K27 R28 D29 G30 K31 Y32 Y38 P41 R42 K43 T44 T45 S61 V62 G63 T67 D68 T69 R72 R75 F80 R81 Q82 M1 R5 F9 G10 S11 K12 H13 N14 H16 R18 R25 R26 K27 R28 D29 G30 K31 Y32 Y38 P41 R42 K43 T44 T45 S61 V62 G63 T67 D68 T69 R72 R75 F80 R81 Q82 P62238 25190797 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQEA 4qs0 Q 3.80 BS01 NUC A 1 P2 K3 S12 K14 M15 Q16 K17 T20 R25 Q26 L31 Y32 K34 V35 K37 R38 S39 K40 K41 Y42 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 R91 R92 N94 Y95 E96 L98 S99 K100 R101 P1 K2 S11 K13 M14 Q15 K16 T19 R24 Q25 L30 Y31 K33 V34 K36 R37 S38 K39 K40 Y41 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 R90 R91 N93 Y94 E95 L97 S98 K99 R100 P62658 25190797 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSKR 4qs0 R 3.80 BS01 NUC A 1 K49 I50 P52 R53 R54 S59 A60 K61 Q63 R64 A67 K68 K71 R72 R74 I75 F81 T82 K31 I32 P34 R35 R36 S41 A42 K43 Q45 R46 A49 K50 K53 R54 R56 I57 F63 T64 P62659 25190797 KAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVRK 4qs0 S 3.80 BS01 NUC A 1 L5 K6 F10 H14 K18 W34 R36 R37 Y52 N53 G54 K55 K70 G72 E73 T77 R78 T79 Y80 G82 L2 K3 F7 H11 K15 W31 R33 R34 Y49 N50 G51 K52 K67 G69 E70 T74 R75 T76 Y77 G79 P62660 25190797 SLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYRG 4qs0 T 3.80 BS01 NUC A 1 N9 L10 S11 A12 K14 R15 H16 R17 Q18 S19 K21 R22 R23 R25 N26 K27 A28 S31 A32 K34 T35 L36 K38 K39 R57 E60 S61 D64 K65 K68 S70 K74 N75 R79 R80 S82 R83 M85 R86 K87 R89 G101 G102 G103 L104 S105 N2 L3 S4 A5 K7 R8 H9 R10 Q11 S12 K14 R15 R16 R18 N19 K20 A21 S24 A25 K27 T28 L29 K31 K32 R50 E53 S54 D57 K58 K61 S63 K67 N68 R72 R73 S75 R76 M78 R79 K80 R82 G94 G95 G96 L97 S98 P62661 25190797 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4qs0 Y 3.80 BS01 NUC A 1 V322 G323 R351 A353 R354 K381 Q500 T501 R504 Q506 G531 K536 S578 E579 M580 V293 G294 R322 A324 R325 K352 Q471 T472 R475 Q477 G502 K507 S549 E550 M551 Q72I01 25190797 KVEYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKGVQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDTLVGEDAPRVILESIEVPEPVIDVAIEPKTKADQEKLSQALARLAEEDPTFRVSTHPETGQTIISGMGELHLEIIVDRLKREFKVDANVGKPQVAYRETITKPVDVEGKFIRQTGGRGQYGHVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARRGQILGMEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLIKG 4qs0 Y 3.80 BS02 NUC V 1 G503 R504 G474 R475 Q72I01 25190797 KVEYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKGVQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDTLVGEDAPRVILESIEVPEPVIDVAIEPKTKADQEKLSQALARLAEEDPTFRVSTHPETGQTIISGMGELHLEIIVDRLKREFKVDANVGKPQVAYRETITKPVDVEGKFIRQTGGRGQYGHVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARRGQILGMEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLIKG 4qs0 Y 3.80 BS03 NUC X 1 Q500 T501 G502 G503 D576 Q471 T472 G473 G474 D547 Q72I01 25190797 KVEYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKGVQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDTLVGEDAPRVILESIEVPEPVIDVAIEPKTKADQEKLSQALARLAEEDPTFRVSTHPETGQTIISGMGELHLEIIVDRLKREFKVDANVGKPQVAYRETITKPVDVEGKFIRQTGGRGQYGHVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARRGQILGMEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLIKG 4qs0 Y 3.80 BS04 GDP Y 1 D22 A23 G24 T26 T27 T84 N137 K138 A263 D19 A20 G21 T23 T24 T55 N108 K109 A234 Q72I01 25190797 KVEYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKGVQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDTLVGEDAPRVILESIEVPEPVIDVAIEPKTKADQEKLSQALARLAEEDPTFRVSTHPETGQTIISGMGELHLEIIVDRLKREFKVDANVGKPQVAYRETITKPVDVEGKFIRQTGGRGQYGHVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARRGQILGMEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLIKG 4qs0 Y 3.80 BS05 FUA Y 1 T66 T84 G86 V88 I461 R465 T37 T55 G57 V59 I432 R436 Q72I01 25190797 KVEYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKGVQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDTLVGEDAPRVILESIEVPEPVIDVAIEPKTKADQEKLSQALARLAEEDPTFRVSTHPETGQTIISGMGELHLEIIVDRLKREFKVDANVGKPQVAYRETITKPVDVEGKFIRQTGGRGQYGHVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARRGQILGMEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLIKG 4qs0 Y 3.80 BS06 MG Y 1 I21 Q112 I18 Q83 Q72I01 25190797 KVEYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKGVQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDTLVGEDAPRVILESIEVPEPVIDVAIEPKTKADQEKLSQALARLAEEDPTFRVSTHPETGQTIISGMGELHLEIIVDRLKREFKVDANVGKPQVAYRETITKPVDVEGKFIRQTGGRGQYGHVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARRGQILGMEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLIKG 4qs1 C 3.80 BS01 NUC A 1 K3 H4 G5 K6 R7 Y8 R9 K37 F38 D39 T41 E43 H45 K47 I131 R135 D167 K168 T169 A171 H173 T208 S212 Y214 T216 T218 M219 G220 K2 H3 G4 K5 R6 Y7 R8 K36 F37 D38 T40 E42 H44 K46 I130 R134 D166 K167 T168 A170 H172 T207 S211 Y213 T215 T217 M218 G219 Q72GV9 25190797 PKHGKRYRALLEKVDPNKVYTIDEAARLVKELATAKFDETVEVHAKLGIDPRRSDQNVRGTVSLPHGLGKQVRVLAIAKGEKIKEAEEAGADYVGGEEIIQKILDGWMDFDAVVATPDVMGAVGSKLGRILGPRGLLPNPKAGTVGFNIGEIIREIKAGRIEFRNDKTGAIHAPVGKASFPPEKLADNIRAFIRALEAHKPEGAKGTFLRSVYVTTTMGPSVRINPHS 4qs1 D 3.80 BS01 NUC A 1 K4 K7 P8 Y9 T10 R13 R14 F15 V18 F21 E30 L33 L37 K38 K39 G41 R43 N44 N45 Q46 G47 R48 I49 T50 R52 F53 R54 H58 K59 R60 L61 Y62 R63 I64 I65 F67 K68 Y84 P86 N87 R88 H96 V98 D99 G100 E101 K102 L147 E148 P149 K150 K151 A153 K154 L155 A156 R157 A158 A159 G160 T161 Y172 S179 E181 R183 H186 H201 K202 V205 L206 G207 K208 A209 G210 R211 R213 W214 R217 R218 P219 H220 V221 R222 G223 A224 A225 M226 N227 D230 G236 G238 R239 P241 R242 R244 A247 S248 P249 W250 W252 Q253 T254 K255 G256 L257 K258 T259 R260 R263 P265 S266 R268 F269 R274 K275 K3 K6 P7 Y8 T9 R12 R13 F14 V17 F20 E29 L32 L36 K37 K38 G40 R42 N43 N44 Q45 G46 R47 I48 T49 R51 F52 R53 H57 K58 R59 L60 Y61 R62 I63 I64 F66 K67 Y83 P85 N86 R87 H95 V97 D98 G99 E100 K101 L146 E147 P148 K149 K150 A152 K153 L154 A155 R156 A157 A158 G159 T160 Y171 S178 E180 R182 H185 H200 K201 V204 L205 G206 K207 A208 G209 R210 R212 W213 R216 R217 P218 H219 V220 R221 G222 A223 A224 M225 N226 D229 G235 G237 R238 P240 R241 R243 A246 S247 P248 W249 W251 Q252 T253 K254 G255 L256 K257 T258 R259 R262 P264 S265 R267 F268 R273 K274 Q72I07 25190797 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIARRKK 4qs1 E 3.80 BS01 NUC A 1 K8 M11 T12 R13 P22 Q35 R37 K41 D42 Y44 N60 R61 P62 K64 H66 I77 L78 R79 E80 R82 R101 K109 G110 R111 G112 F113 G115 M117 K118 R119 F122 A123 D127 S128 H129 G130 A131 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 G148 R149 V150 Y151 K152 G153 K154 K155 M156 A157 G158 H159 Y160 R164 V165 T166 M168 N169 L170 K185 G186 A187 V188 P189 P191 N192 R199 K202 K203 A204 A205 K8 M11 T12 R13 P22 Q35 R37 K41 D42 Y44 N60 R61 P62 K64 H66 I77 L78 R79 E80 R82 R101 K109 G110 R111 G112 F113 G115 M117 K118 R119 F122 A123 D127 S128 H129 G130 A131 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 G148 R149 V150 Y151 K152 G153 K154 K155 M156 A157 G158 H159 Y160 R164 V165 T166 M168 N169 L170 K185 G186 A187 V188 P189 P191 N192 R199 K202 K203 A204 A205 Q72I04 25190797 MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLGFLPQNPKRVNRPLKGHFAKAGVEPVRILREIRDFNPEGDTVTVEIFKPGERVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNRKTPGRVYKGKKMAGHYGAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRETKKAA 4qs1 F 3.80 BS01 NUC A 1 N29 H31 W34 E35 R38 W39 L41 K43 R44 R45 R46 G47 T48 A49 S50 T51 T53 R54 G55 A58 Y59 S60 G61 R62 K63 P66 Q67 K68 H69 G71 R72 R74 H75 G76 D77 I82 F83 V84 G85 F90 G91 P92 P94 R95 Y97 Y99 T100 L101 P102 K103 V105 R106 K107 K108 G134 K135 T136 K137 R165 A166 R168 N169 L170 P171 E179 G180 L181 Y184 N29 H31 W34 E35 R38 W39 L41 K43 R44 R45 R46 G47 T48 A49 S50 T51 T53 R54 G55 A58 Y59 S60 G61 R62 K63 P66 Q67 K68 H69 G71 R72 R74 H75 G76 D77 I82 F83 V84 G85 F90 G91 P92 P94 R95 Y97 Y99 T100 L101 P102 K103 V105 R106 K107 K108 G134 K135 T136 K137 R165 A166 R168 N169 L170 P171 E179 G180 L181 Y184 Q72I05 25190797 MKEVAVYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIGG 4qs1 G 3.80 BS01 NUC A 1 K36 V38 N40 G42 L43 K47 T71 R72 A73 K74 I77 N79 F80 G89 L90 R91 S124 F125 D126 R128 N130 N132 L133 G134 L135 R136 G154 D156 V160 K35 V37 N39 G41 L42 K46 T70 R71 A72 K73 I76 N78 F79 G88 L89 R90 S123 F124 D125 R127 N129 N131 L132 G133 L134 R135 G153 D155 V159 Q72I16 25190797 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4qs1 G 3.80 BS02 NUC B 1 N27 V28 W29 E30 K67 A69 V70 R72 V92 T93 R95 N26 V27 W28 E29 K66 A68 V69 R71 V91 T92 R94 Q72I16 25190797 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4qs1 H 3.80 BS01 NUC A 1 R59 K62 S63 L64 G66 L67 T70 L71 N74 G108 F109 S110 H111 K138 Q139 G142 Q143 A146 R152 Y157 K160 L171 K172 P173 K175 A176 G177 R48 K51 S52 L53 G55 L56 T59 L60 N63 G97 F98 S99 H100 K127 Q128 G131 Q132 A135 R141 Y146 K149 L160 K161 P162 K164 A165 G166 Q72I19 25190797 PKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRLKPGKAGA 4qs1 K 3.80 BS01 NUC A 1 P73 A74 K86 G87 A88 H89 K90 P91 L115 N116 T117 A122 A123 R125 M126 S130 S133 M134 P72 A73 K85 G86 A87 H88 K89 P90 L114 N115 T116 A121 A122 R124 M125 S129 S132 M133 P62442 25190797 KKVVAVVKLQLPAGKATPAPPVGPALGQHGANIMEFVKAFNAATANMGDAIVPVEITIYADRSFTFVTKTPPASYLIRKAAGLEKGAHKPGREKVGRITWEQVLEIAKQKMPDLNTTDLEAAARMIAGSARSMGVEVVGA 4qs1 N 3.80 BS01 NUC A 1 K2 L23 G24 R25 T28 G36 K37 H38 P40 D41 W42 T43 T63 G64 K66 Y72 T73 R74 Y75 Y78 G80 L82 K83 K84 K89 M90 A92 T93 H94 P95 P108 K109 G110 P111 G113 R114 R115 L116 F117 K118 R119 K121 H130 K2 L23 G24 R25 T28 G36 K37 H38 P40 D41 W42 T43 T63 G64 K66 Y72 T73 R74 Y75 Y78 G80 L82 K83 K84 K89 M90 A92 T93 H94 P95 P108 K109 G110 P111 G113 R114 R115 L116 F117 K118 R119 K121 H130 Q72IN1 25190797 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKLE 4qs1 O 3.80 BS01 NUC A 1 M1 Q3 Q5 T6 Y7 I22 R23 L25 K26 G27 S28 N29 A30 Y32 V40 S42 K44 G55 V57 K59 K66 K67 E68 K70 N82 M1 Q3 Q5 T6 Y7 I22 R23 L25 K26 G27 S28 N29 A30 Y32 V40 S42 K44 G55 V57 K59 K66 K67 E68 K70 N82 Q72I14 25190797 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 4qs1 P 3.80 BS01 NUC A 1 R7 P8 P10 G11 A12 N13 K14 R16 K17 R18 V19 G20 R21 G24 S25 G26 H27 K29 T30 A31 T32 R33 H35 K36 Q38 K39 S40 R41 S42 G43 G44 L45 K46 D47 P48 F51 E52 G53 G54 R55 S56 M60 R61 L62 P63 K64 R65 G66 M67 Q68 G69 Q70 V71 P72 G73 E74 R77 N84 R90 G104 L105 K107 K108 K113 L115 G116 E117 S131 K132 S133 R3 P4 P6 G7 A8 N9 K10 R12 K13 R14 V15 G16 R17 G20 S21 G22 H23 K25 T26 A27 T28 R29 H31 K32 Q34 K35 S36 R37 S38 G39 G40 L41 K42 D43 P44 F47 E48 G49 G50 R51 S52 M56 R57 L58 P59 K60 R61 G62 M63 Q64 G65 Q66 V67 P68 G69 E70 R73 N80 R86 G100 L101 K103 K104 K109 L111 G112 E113 S127 K128 S129 Q72I23 25190797 DLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA 4qs1 Q 3.80 BS01 NUC A 1 P4 R5 M7 K8 Y9 K11 Q12 Q13 R14 G15 R16 A20 K22 G24 Y26 A28 F29 W41 Q45 Q46 V52 R56 F65 I66 R67 F69 Y74 T75 K76 K77 E80 R82 M83 G84 K85 G86 K87 R119 I120 H123 K124 L125 P126 K128 A140 Q141 P4 R5 M7 K8 Y9 K11 Q12 Q13 R14 G15 R16 A20 K22 G24 Y26 A28 F29 W41 Q45 Q46 V52 R56 F65 I66 R67 F69 Y74 T75 K76 K77 E80 R82 M83 G84 K85 G86 K87 R119 I120 H123 K124 L125 P126 K128 A140 Q141 Q72I11 25190797 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4qs1 R 3.80 BS01 NUC A 1 H3 L4 K5 R8 K9 L10 N11 R12 H13 S14 S15 H16 R17 A19 L20 N23 Q24 K26 S27 H31 I34 T35 T37 P39 K40 K42 R45 G46 D49 H50 H53 L54 L60 H61 R64 R68 Q71 R90 G92 G93 Y94 T95 R96 L98 K99 R104 G106 D107 A109 H2 L3 K4 R7 K8 L9 N10 R11 H12 S13 S14 H15 R16 A18 L19 N22 Q23 K25 S26 H30 I33 T34 T36 P38 K39 K41 R44 G45 D48 H49 H52 L53 L59 H60 R63 R67 Q70 R89 G91 G92 Y93 T94 R95 L97 K98 R103 G105 D106 A108 Q72I33 25190797 RHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE 4qs1 S 3.80 BS01 NUC A 1 V14 R15 K19 Q84 V85 Y92 R106 E107 G108 G109 V4 R5 K9 Q74 V75 Y82 R96 E97 G98 G99 Q72I20 25190797 KFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGG 4qs1 S 3.80 BS02 NUC B 1 R17 R25 S27 V28 F29 R30 S31 L32 K33 H34 Y36 Q38 G45 V46 T47 L48 S50 N61 K62 T63 R89 P91 Y92 K93 H95 R97 R7 R15 S17 V18 F19 R20 S21 L22 K23 H24 Y26 Q28 G35 V36 T37 L38 S40 N51 K52 T53 R79 P81 Y82 K83 H85 R87 Q72I20 25190797 KFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGG 4qs1 T 3.80 BS01 NUC A 1 N2 R3 G4 A5 R23 P24 R51 R53 R54 N55 N58 T60 I75 R93 R95 R96 A97 K98 Y100 F101 K113 N2 R3 G4 A5 R23 P24 R51 R53 R54 N55 N58 T60 I75 R93 R95 R96 A97 K98 Y100 F101 K113 Q72JU9 25190797 MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVIRIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLYFIRNLSDREIRRKLRADRKRIDQDRAAERAAKEEAQKA 4qs1 U 3.80 BS01 NUC A 1 P2 R3 A4 K5 T6 G7 V8 V9 R10 R11 R12 K13 H14 K15 K16 K22 G23 Y24 W25 G26 L27 R28 S29 K30 S31 F32 R33 K34 R36 E37 A42 Y45 A46 Y47 H49 R50 K51 R52 R53 K54 R55 F57 R58 R59 W61 I62 V63 N66 R70 N75 Y76 S77 I80 H81 K84 R92 K93 N94 P1 R2 A3 K4 T5 G6 V7 V8 R9 R10 R11 K12 H13 K14 K15 K21 G22 Y23 W24 G25 L26 R27 S28 K29 S30 F31 R32 K33 R35 E36 A41 Y44 A45 Y46 H48 R49 K50 R51 R52 K53 R54 F56 R57 R58 W60 I61 V62 N65 R69 N74 Y75 S76 I79 H80 K83 R91 K92 N93 Q72L76 25190797 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQG 4qs1 V 3.80 BS01 NUC A 1 G8 G9 Q11 E23 K24 R66 K69 K74 K76 A77 K78 Q80 Y81 R82 R83 K84 K85 G86 H87 Q89 P90 G8 G9 Q11 E23 K24 R66 K69 K74 K76 A77 K78 Q80 Y81 R82 R83 K84 K85 G86 H87 Q89 P90 Q72HR2 25190797 MFAIVKTGGKQYRVEPGLKLRVEKLDAEPGATVELPVLLLGGEKTVVGTPVVEGASVVAEVLGHGRGKKILVSKFKAKVQYRRKKGHRQPYTELLIKEIRG 4qs1 W 3.80 BS01 NUC A 1 K4 I6 A7 R8 R11 I12 S13 R15 R18 R25 N40 K41 R42 K49 E52 S53 A56 N57 N61 H62 Y75 D77 E78 G79 K83 P87 R88 A89 R90 G91 R92 A93 D94 I95 I96 K97 K98 R99 H102 K4 I6 A7 R8 R11 I12 S13 R15 R18 R25 N40 K41 R42 K49 E52 S53 A56 N57 N61 H62 Y75 D77 E78 G79 K83 P87 R88 A89 R90 G91 R92 A93 D94 I95 I96 K97 K98 R99 H102 Q72I09 25190797 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHGK 4qs1 X 3.80 BS01 NUC A 1 T3 D6 S14 E15 K16 H31 K33 T35 K36 T37 E38 K40 N41 K53 N55 T56 L57 H58 R60 K62 K63 K64 R65 L66 R68 Y69 L70 G71 R73 P74 D75 K78 I80 T1 D4 S12 E13 K14 H29 K31 T33 K34 T35 E36 K38 N39 K51 N53 T54 L55 H56 R58 K60 K61 K62 R63 L64 R66 Y67 L68 G69 R71 P72 D73 K76 I78 Q72I06 25190797 TAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEGL 4qs1 Y 3.80 BS01 NUC A 1 R2 V3 K4 M5 V7 K9 S17 G18 K19 K21 V30 L31 K33 I44 V45 K46 K47 A48 R50 G59 F60 E62 H68 S70 K71 V72 R73 R84 V85 R97 R1 V2 K3 M4 V6 K8 S16 G17 K18 K20 V29 L30 K32 I43 V44 K45 K46 A47 R49 G58 F59 E61 H67 S69 K70 V71 R72 R83 V84 R96 Q72I15 25190797 RVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCGGALDT 4qs1 Z 3.80 BS01 NUC A 1 R112 Q118 S149 E169 T170 A173 V175 R110 Q116 S147 E167 T168 A171 V173 Q72IA7 25190797 YRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKLAEEA 4qs1 Z 3.80 BS02 NUC B 1 R10 P15 R19 V27 Y29 R31 N34 R72 Q73 N75 E84 H85 D87 F89 R8 P13 R17 V25 Y27 R29 N32 R70 Q71 N73 E82 H83 D85 F87 Q72IA7 25190797 YRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKLAEEA 4qs1 0 3.80 BS01 NUC A 1 K4 T10 R11 N12 R14 D15 S16 Q17 K19 R20 V23 K24 R25 Y26 E27 G28 Q29 R32 A33 G34 N35 I36 R39 R41 G42 T43 R44 G54 R55 D56 F57 T58 F60 L62 F69 L75 R77 K3 T9 R10 N11 R13 D14 S15 Q16 K18 R19 V22 K23 R24 Y25 E26 G27 Q28 R31 A32 G33 N34 I35 R38 R40 G41 T42 R43 G53 R54 D55 F56 T57 F59 L61 F68 L74 R76 Q72HR3 25190797 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPLA 4qs1 0 3.80 BS02 NUC B 1 R72 G73 R71 G72 Q72HR3 25190797 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPLA 4qs1 1 3.80 BS01 NUC A 1 K3 K10 R11 N16 I18 R20 R21 K25 T35 I37 R40 Q42 Y43 P44 N45 L46 Q47 R50 R52 R61 A64 S65 H66 P68 K69 G79 L80 K81 K1 K8 R9 N14 I16 R18 R19 K23 T33 I35 R38 Q40 Y41 P42 N43 L44 Q45 R48 R50 R59 A62 S63 H64 P66 K67 G77 L78 K79 Q72G84 25190797 KVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELL 4qs1 3 3.80 BS01 NUC A 1 K10 S11 I13 G14 Y15 P16 K17 D18 A21 K24 A25 R29 R30 L31 Q32 A42 I43 G45 N46 E48 K49 K10 S11 I13 G14 Y15 P16 K17 D18 A21 K24 A25 R29 R30 L31 Q32 A42 I43 G45 N46 E48 K49 Q72I22 25190797 MPRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVAHLVRVEVVE 4qs1 5 3.80 BS01 NUC A 1 A2 K3 H4 P5 V6 P7 K8 K9 K10 T11 S12 K13 A14 R15 R16 R19 R20 S21 H22 T29 V31 P32 P34 P42 H43 Y51 A1 K2 H3 P4 V5 P6 K7 K8 K9 T10 S11 K12 A13 R14 R15 R18 R19 S20 H21 T28 V30 P31 P33 P41 H42 Y50 P62652 25190797 AKHPVPKKKTSKARRDARRSHHALTPPTLVPCPECKAMKPPHTVCPECGYYAGRKVLEV 4qs1 6 3.80 BS01 NUC A 1 V5 R6 K8 L10 E12 R19 Y21 T23 E24 K27 T30 N32 E35 R37 K38 Y39 W42 H46 V1 R2 K4 L6 E8 R15 Y17 T19 E20 K23 T26 N28 E31 R33 K34 Y35 W38 H42 Q72GW3 25190797 VRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVKI 4qs1 7 3.80 BS01 NUC A 1 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 M22 T24 P25 R28 K29 K32 R33 R34 R35 K37 G38 W40 R41 L42 K48 R49 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 M22 T24 P25 R28 K29 K32 R33 R34 R35 K37 G38 W40 R41 L42 K48 R49 P80340 25190797 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRKR 4qs1 8 3.80 BS01 NUC A 1 P2 K3 M4 K5 T6 H7 K8 K11 R13 K15 T17 A18 K26 T27 G28 K29 H31 L32 N33 W34 Q35 S37 G38 K39 E40 I41 R42 R46 K47 K52 L61 L62 P1 K2 M3 K4 T5 H6 K7 K10 R12 K14 T16 A17 K25 T26 G27 K28 H30 L31 N32 W33 Q34 S36 G37 K38 E39 I40 R41 R45 K46 K51 L60 L61 Q72L77 25190797 PKMKTHKGAKKRVKITASGKVVAMKTGKRHLNWQKSGKEIRQKGRKFVLAKPEAERIKLLLPYE 4qs1 9 3.80 BS01 NUC A 1 M1 K2 V3 R4 A5 S6 V7 K8 R9 V16 I17 R18 R19 H20 R22 Y24 P30 K31 K33 R35 Q36 G37 M1 K2 V3 R4 A5 S6 V7 K8 R9 V16 I17 R18 R19 H20 R22 Y24 P30 K31 K33 R35 Q36 G37 Q72I28 25190797 MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG 4qs2 B 3.80 BS01 NUC A 1 K22 W24 R96 L98 G99 T103 N104 T107 R111 K133 R144 K147 E176 K179 K16 W18 R90 L92 G93 T97 N98 T101 R105 K127 R138 K141 E170 K173 P62662 25190797 VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQE 4qs2 C 3.80 BS01 NUC A 1 G2 N3 K4 I5 H6 F10 K27 R127 S154 R156 E161 Q162 A163 R172 V173 P174 L175 H176 T177 L178 R179 F186 Y193 G194 V195 L196 G197 K199 G1 N2 K3 I4 H5 F9 K26 R126 S153 R155 E160 Q161 A162 R171 V172 P173 L174 H175 T176 L177 R178 F185 Y192 G193 V194 L195 G196 K198 P62663 25190797 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEVI 4qs2 C 3.80 BS02 NUC V 1 G74 R119 F128 R131 R132 R140 A160 E161 Q162 G73 R118 F127 R130 R131 R139 A159 E160 Q161 P62663 25190797 GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEVI 4qs2 D 3.80 BS01 NUC A 1 G2 R3 I5 G6 P7 V8 R10 K22 E24 R25 K30 A32 R35 R36 P40 G41 Q42 H43 Y54 Q62 E72 Q74 N77 K84 K85 S113 R115 Q116 R118 Q119 R122 H123 H125 R131 R132 V133 D134 L135 S137 Y138 E150 K151 R209 G1 R2 I4 G5 P6 V7 R9 K21 E23 R24 K29 A31 R34 R35 P39 G40 Q41 H42 Y53 Q61 E71 Q73 N76 K83 K84 S112 R114 Q115 R117 Q118 R121 H122 H124 R130 R131 V132 D133 L134 S136 Y137 E149 K150 R208 P62664 25190797 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4qs2 D 3.80 BS02 NUC V 1 K46 R47 K45 R46 P62664 25190797 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4qs2 E 3.80 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 R24 R25 R27 F45 P49 K57 Y60 Y61 E83 F84 G85 A86 A102 G103 R107 L119 T120 K121 E122 L123 S125 R126 N127 I129 N130 Y133 R10 T12 A13 R14 M15 Q16 R20 R21 R23 F41 P45 K53 Y56 Y57 E79 F80 G81 A82 A98 G99 R103 L115 T116 K117 E118 L119 S121 R122 N123 I125 N126 Y129 P62665 25190797 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKGE 4qs2 F 3.80 BS01 NUC A 1 I52 K54 N73 R77 R80 R87 M89 V90 V91 K92 I52 K54 N73 R77 R80 R87 M89 V90 V91 K92 P62666 25190797 MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA 4qs2 G 3.80 BS01 NUC A 1 A2 R3 R4 R5 R6 A7 R10 N28 K29 M31 R32 D33 G34 K35 K36 N37 L38 R41 S77 R79 R94 R95 S98 R102 N109 R114 A116 R119 W156 A1 R2 R3 R4 R5 A6 R9 N27 K28 M30 R31 D32 G33 K34 K35 N36 L37 R40 S76 R78 R93 R94 S97 R101 N108 R113 A115 R118 W155 P62667 25190797 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4qs2 H 3.80 BS01 NUC A 1 M1 L2 T3 D4 P5 A7 D8 T11 R12 R14 N15 R18 V19 K21 A28 S29 R30 F31 K56 R85 K88 P89 G90 R91 R92 Y94 V95 G96 R105 S113 T114 S115 K116 G128 V129 G130 G131 M1 L2 T3 D4 P5 A7 D8 T11 R12 R14 N15 R18 V19 K21 A28 S29 R30 F31 K56 R85 K88 P89 G90 R91 R92 Y94 V95 G96 R105 S113 T114 S115 K116 G128 V129 G130 G131 P62668 25190797 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4qs2 I 3.80 BS01 NUC A 1 Q3 Y5 R9 K11 E12 V14 R16 F18 R20 L40 Y62 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 A106 R107 V108 V109 E110 R111 K112 K113 Y114 K118 A119 R120 R121 A122 P123 Q124 Y125 S126 R128 Q2 Y4 R8 K10 E11 V13 R15 F17 R19 L39 Y61 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 A105 R106 V107 V108 E109 R110 K111 K112 Y113 K117 A118 R119 R120 A121 P122 Q123 Y124 S125 R127 P62669 25190797 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4qs2 J 3.80 BS01 NUC A 1 R5 K7 D17 G36 P37 I38 P39 L40 P41 R43 R45 R46 R51 G52 P53 F54 K55 H56 K57 S59 R60 E61 H62 R66 R70 D73 R3 K5 D15 G34 P35 I36 P37 L38 P39 R41 R43 R44 R49 G50 P51 F52 K53 H54 K55 S57 R58 E59 H60 R64 R68 D71 P62653 25190797 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKTV 4qs2 K 3.80 BS01 NUC A 1 R12 Y20 H22 N26 N27 I29 T31 T33 D36 G37 N38 P39 W42 G46 V47 K51 G52 S53 K55 R85 P113 V114 P115 H116 N117 G118 C119 R120 P121 K122 K123 K124 R126 R2 Y10 H12 N16 N17 I19 T21 T23 D26 G27 N28 P29 W32 G36 V37 K41 G42 S43 K45 R75 P103 V104 P105 H106 N107 G108 C109 R110 P111 K112 K113 K114 R116 P62654 25190797 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS 4qs2 L 3.80 BS01 NUC A 1 P5 T6 I7 N8 Q9 R15 E16 K17 K20 K21 S22 V24 K28 G29 P31 F32 R33 R34 V43 K46 K47 P48 N49 S50 A51 L52 R53 T61 E65 Y69 P71 G72 E73 G74 L84 R86 G87 V90 K91 D92 P94 R97 R113 K114 K115 S116 R117 S118 K119 Y120 K123 K124 P1 T2 I3 N4 Q5 R11 E12 K13 K16 K17 S18 V20 K24 G25 P27 F28 R29 R30 V39 K42 K43 P44 N45 S46 A47 L48 R49 T57 E61 Y65 P67 G68 E69 G70 L80 R82 G83 V86 K87 D88 P90 R93 R109 K110 K111 S112 R113 S114 K115 Y116 K119 K120 P61941 25190797 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEAA 4qs2 M 3.80 BS01 NUC A 1 R14 V17 Y21 I22 Y23 G24 I25 G26 R29 L70 R80 L81 Y87 R91 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 R108 T109 K111 P113 R114 K115 V117 G119 K120 K122 P124 R125 K126 R13 V16 Y20 I21 Y22 G23 I24 G25 R28 L69 R79 L80 Y86 R90 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 R107 T108 K110 P112 R113 K114 V116 G118 K119 K121 P123 R124 K125 P62655 25190797 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKKAPRK 4qs2 N 3.80 BS01 NUC A 1 A2 R3 K4 A5 L6 E8 K9 R12 F16 K17 V18 R19 Y21 T22 C27 G28 R29 R31 S32 V33 Y34 R35 I42 R45 K58 S60 W61 A1 R2 K3 A4 L5 E7 K8 R11 F15 K16 V17 R18 Y20 T21 C26 G27 R28 R30 S31 V32 Y33 R34 I41 R44 K57 S59 W60 P62656 25190797 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4qs2 O 3.80 BS01 NUC A 1 P2 K5 K8 Q9 D21 T22 G23 S24 Q28 L31 R38 L39 H42 K48 D49 H50 H51 S52 H53 R54 L57 M58 M59 R64 R65 L66 Y69 R72 P1 K4 K7 Q8 D20 T21 G22 S23 Q27 L30 R37 L38 H41 K47 D48 H49 H50 S51 H52 R53 L56 M57 M58 R63 R64 L65 Y68 R71 P62657 25190797 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 4qs2 P 3.80 BS01 NUC A 1 M1 K3 R5 L6 F9 G10 S11 K12 H13 H16 R18 D23 R25 R26 K27 R28 D29 G30 K31 Y32 I33 Y38 P41 R42 K43 T44 T45 S61 V62 T67 D68 T69 R72 R75 F80 R81 Q82 E83 A84 M1 K3 R5 L6 F9 G10 S11 K12 H13 H16 R18 D23 R25 R26 K27 R28 D29 G30 K31 Y32 I33 Y38 P41 R42 K43 T44 T45 S61 V62 T67 D68 T69 R72 R75 F80 R81 Q82 E83 A84 P62238 25190797 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQEA 4qs2 Q 3.80 BS01 NUC A 1 P2 K3 M15 Q16 K17 T18 R25 Q26 L31 Y32 K34 K37 R38 K40 K41 Y42 E61 S62 R63 P64 I65 S66 K67 R68 K69 R70 F71 R72 I90 R91 R92 N94 Y95 E96 S97 L98 K100 P1 K2 M14 Q15 K16 T17 R24 Q25 L30 Y31 K33 K36 R37 K39 K40 Y41 E60 S61 R62 P63 I64 S65 K66 R67 K68 R69 F70 R71 I89 R90 R91 N93 Y94 E95 S96 L97 K99 P62658 25190797 PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSKR 4qs2 T 3.80 BS01 NUC A 1 L10 S11 A12 K14 R15 H16 R17 S19 K21 R22 R23 N26 K27 A28 S31 A32 K34 T35 K38 R57 E60 S61 D64 K65 K68 S70 L72 K74 N75 A76 A78 R79 R80 K81 S82 R83 M85 R86 G102 G103 S105 A106 L3 S4 A5 K7 R8 H9 R10 S12 K14 R15 R16 N19 K20 A21 S24 A25 K27 T28 K31 R50 E53 S54 D57 K58 K61 S63 L65 K67 N68 A69 A71 R72 R73 K74 S75 R76 M78 R79 G95 G96 S98 A99 P62661 25190797 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4qs2 Y 3.80 BS01 NUC A 1 Y321 V322 G323 G338 Y340 R351 R354 K381 Q426 R430 Q500 T501 R504 Q506 G531 M580 Y292 V293 G294 G309 Y311 R322 R325 K352 Q397 R401 Q471 T472 R475 Q477 G502 M551 Q72I01 25190797 KVEYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKGVQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDTLVGEDAPRVILESIEVPEPVIDVAIEPKTKADQEKLSQALARLAEEDPTFRVSTHPETGQTIISGMGELHLEIIVDRLKREFKVDANVGKPQVAYRETITKPVDVEGKFIRQTGGRGQYGHVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARRGQILGMEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLIKG 4qs2 Y 3.80 BS02 NUC X 1 K496 I498 Q500 T501 G502 Y507 D576 K467 I469 Q471 T472 G473 Y478 D547 Q72I01 25190797 KVEYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKGVQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDTLVGEDAPRVILESIEVPEPVIDVAIEPKTKADQEKLSQALARLAEEDPTFRVSTHPETGQTIISGMGELHLEIIVDRLKREFKVDANVGKPQVAYRETITKPVDVEGKFIRQTGGRGQYGHVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARRGQILGMEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLIKG 4qs2 Y 3.80 BS03 GDP Y 1 I21 D22 A23 G24 K25 T26 T27 T84 N137 K138 D140 S262 A263 L264 I18 D19 A20 G21 K22 T23 T24 T55 N108 K109 D111 S233 A234 L235 Q72I01 25190797 KVEYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKGVQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDTLVGEDAPRVILESIEVPEPVIDVAIEPKTKADQEKLSQALARLAEEDPTFRVSTHPETGQTIISGMGELHLEIIVDRLKREFKVDANVGKPQVAYRETITKPVDVEGKFIRQTGGRGQYGHVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARRGQILGMEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLIKG 4qs2 Y 3.80 BS04 FUA Y 1 T66 T84 I461 I462 R465 T37 T55 I432 I433 R436 Q72I01 25190797 KVEYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKGVQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDTLVGEDAPRVILESIEVPEPVIDVAIEPKTKADQEKLSQALARLAEEDPTFRVSTHPETGQTIISGMGELHLEIIVDRLKREFKVDANVGKPQVAYRETITKPVDVEGKFIRQTGGRGQYGHVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARRGQILGMEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLIKG 4qs3 C 3.80 BS01 NUC A 1 P2 K3 K6 R7 Y8 A36 K37 F38 T41 E43 H45 K47 R135 D167 K168 T169 A171 H173 K178 S212 Y214 T216 T218 M219 G220 P1 K2 K5 R6 Y7 A35 K36 F37 T40 E42 H44 K46 R134 D166 K167 T168 A170 H172 K177 S211 Y213 T215 T217 M218 G219 Q72GV9 25190797 PKHGKRYRALLEKVDPNKVYTIDEAARLVKELATAKFDETVEVHAKLGIDPRRSDQNVRGTVSLPHGLGKQVRVLAIAKGEKIKEAEEAGADYVGGEEIIQKILDGWMDFDAVVATPDVMGAVGSKLGRILGPRGLLPNPKAGTVGFNIGEIIREIKAGRIEFRNDKTGAIHAPVGKASFPPEKLADNIRAFIRALEAHKPEGAKGTFLRSVYVTTTMGPSVRINPHS 4qs3 D 3.80 BS01 NUC A 1 K7 P8 Y9 T10 P11 R13 F15 F21 L33 L37 K38 K39 T40 G41 R43 N44 N45 Q46 G47 R48 I49 T50 R52 R54 G55 G56 H58 K59 L61 Y62 R63 K68 K72 Y84 P86 R88 Y97 V98 D99 G100 E101 E148 P149 K150 K151 K154 L155 A156 R157 A158 A159 G160 Y172 S179 R183 H186 H201 L206 G207 K208 A209 G210 R213 W214 R217 R218 P219 H220 V221 R222 G223 A224 A225 M226 N227 D230 H231 P232 G238 R239 P241 R242 R244 A247 S248 P249 W250 W252 Q253 T254 K255 G256 L257 K258 T259 R260 R262 R263 P265 S266 F269 R274 K6 P7 Y8 T9 P10 R12 F14 F20 L32 L36 K37 K38 T39 G40 R42 N43 N44 Q45 G46 R47 I48 T49 R51 R53 G54 G55 H57 K58 L60 Y61 R62 K67 K71 Y83 P85 R87 Y96 V97 D98 G99 E100 E147 P148 K149 K150 K153 L154 A155 R156 A157 A158 G159 Y171 S178 R182 H185 H200 L205 G206 K207 A208 G209 R212 W213 R216 R217 P218 H219 V220 R221 G222 A223 A224 M225 N226 D229 H230 P231 G237 R238 P240 R241 R243 A246 S247 P248 W249 W251 Q252 T253 K254 G255 L256 K257 T258 R259 R261 R262 P264 S265 F268 R273 Q72I07 25190797 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIARRKK 4qs3 E 3.80 BS01 NUC A 1 M11 T12 R13 P22 Q35 R37 D42 Y44 R58 N60 R61 P62 H66 I77 L78 R79 E80 R82 K109 G110 R111 G112 F113 G115 K118 R119 F122 A123 G124 D127 S128 H129 G130 A131 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 P147 G148 R149 V150 Y151 K152 G153 K154 M156 A157 G158 H159 Y160 R164 T166 M168 N169 K185 G186 A187 V188 P189 G190 P191 N192 R199 K202 K203 A204 A205 M11 T12 R13 P22 Q35 R37 D42 Y44 R58 N60 R61 P62 H66 I77 L78 R79 E80 R82 K109 G110 R111 G112 F113 G115 K118 R119 F122 A123 G124 D127 S128 H129 G130 A131 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 P147 G148 R149 V150 Y151 K152 G153 K154 M156 A157 G158 H159 Y160 R164 T166 M168 N169 K185 G186 A187 V188 P189 G190 P191 N192 R199 K202 K203 A204 A205 Q72I04 25190797 MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLGFLPQNPKRVNRPLKGHFAKAGVEPVRILREIRDFNPEGDTVTVEIFKPGERVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNRKTPGRVYKGKKMAGHYGAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRETKKAA 4qs3 F 3.80 BS01 NUC A 1 N29 H31 L32 W34 E35 R38 W39 L41 K43 R44 R45 R46 T48 S50 T51 T53 R54 G55 E56 V57 A58 Y59 S60 R62 K63 Q67 K68 H69 G71 R72 A73 R74 H75 G76 D77 I78 I82 F83 V84 V88 V89 F90 G91 P92 P94 D96 Y97 Y99 T100 L101 P102 K103 V105 R106 K107 K108 G134 K135 T136 K137 L140 R165 A166 R168 N169 L170 P171 E179 G180 Y184 R205 N29 H31 L32 W34 E35 R38 W39 L41 K43 R44 R45 R46 T48 S50 T51 T53 R54 G55 E56 V57 A58 Y59 S60 R62 K63 Q67 K68 H69 G71 R72 A73 R74 H75 G76 D77 I78 I82 F83 V84 V88 V89 F90 G91 P92 P94 D96 Y97 Y99 T100 L101 P102 K103 V105 R106 K107 K108 G134 K135 T136 K137 L140 R165 A166 R168 N169 L170 P171 E179 G180 Y184 R205 Q72I05 25190797 MKEVAVYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIGG 4qs3 G 3.80 BS01 NUC A 1 K36 V38 N40 Q41 G42 L43 G44 E45 K47 T71 R72 A73 K74 I77 N79 F80 G89 R91 N123 S124 F125 D126 R128 N130 N132 L133 G134 L135 R136 R153 G154 M155 D156 V160 K35 V37 N39 Q40 G41 L42 G43 E44 K46 T70 R71 A72 K73 I76 N78 F79 G88 R90 N122 S123 F124 D125 R127 N129 N131 L132 G133 L134 R135 R152 G153 M154 D155 V159 Q72I16 25190797 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4qs3 G 3.80 BS02 NUC B 1 N27 W29 E30 K67 A69 V70 R72 V92 T93 R95 N26 W28 E29 K66 A68 V69 R71 V91 T92 R94 Q72I16 25190797 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4qs3 H 3.80 BS01 NUC A 1 R59 K62 S63 H65 G66 L67 T70 L71 N74 F109 S110 H111 K138 Q139 G142 Q143 A146 Y157 H158 L171 P173 K175 A176 G177 R48 K51 S52 H54 G55 L56 T59 L60 N63 F98 S99 H100 K127 Q128 G131 Q132 A135 Y146 H147 L160 P162 K164 A165 G166 Q72I19 25190797 PKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRLKPGKAGA 4qs3 K 3.80 BS01 NUC A 1 Q11 P73 S75 K86 G87 H89 K90 P91 G92 L115 N116 T117 A122 M126 G129 S130 S133 M134 Q10 P72 S74 K85 G86 H88 K89 P90 G91 L114 N115 T116 A121 M125 G128 S129 S132 M133 P62442 25190797 KKVVAVVKLQLPAGKATPAPPVGPALGQHGANIMEFVKAFNAATANMGDAIVPVEITIYADRSFTFVTKTPPASYLIRKAAGLEKGAHKPGREKVGRITWEQVLEIAKQKMPDLNTTDLEAAARMIAGSARSMGVEVVGA 4qs3 N 3.80 BS01 NUC A 1 M1 L23 G24 R25 A27 T28 G36 K37 H38 R39 P40 D41 W42 T43 T63 K65 K66 E68 Y72 T73 R74 Y75 G80 L82 K83 K84 K89 M90 A92 T93 H94 L107 P108 K109 G110 P111 G113 R114 F117 K118 R119 K121 H130 M1 L23 G24 R25 A27 T28 G36 K37 H38 R39 P40 D41 W42 T43 T63 K65 K66 E68 Y72 T73 R74 Y75 G80 L82 K83 K84 K89 M90 A92 T93 H94 L107 P108 K109 G110 P111 G113 R114 F117 K118 R119 K121 H130 Q72IN1 25190797 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKLE 4qs3 O 3.80 BS01 NUC A 1 M1 I2 Q3 P4 Q5 T6 Y7 I22 R23 L25 K26 G27 S28 N29 A30 K31 Y32 S42 V43 K59 K66 K67 E68 K70 A76 N82 M1 I2 Q3 P4 Q5 T6 Y7 I22 R23 L25 K26 G27 S28 N29 A30 K31 Y32 S42 V43 K59 K66 K67 E68 K70 A76 N82 Q72I14 25190797 MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRGAVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFGPVARELREKGFMKIVSLAPEVL 4qs3 P 3.80 BS01 NUC A 1 R7 P8 N9 P10 G11 A12 K14 R15 R16 K17 R18 V19 G20 R21 G24 S25 G26 H27 K29 T30 A31 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 G44 L45 K46 D47 P48 F51 E52 G54 R55 L59 M60 L62 P63 K64 R65 G66 M67 Q68 G69 Q70 V71 P72 G73 E74 I75 R77 Y80 Q81 N84 G104 K107 K108 K113 L115 G116 E117 S131 K132 S133 R3 P4 N5 P6 G7 A8 K10 R11 R12 K13 R14 V15 G16 R17 G20 S21 G22 H23 K25 T26 A27 T28 R29 G30 H31 K32 G33 Q34 K35 S36 R37 S38 G39 G40 L41 K42 D43 P44 F47 E48 G50 R51 L55 M56 L58 P59 K60 R61 G62 M63 Q64 G65 Q66 V67 P68 G69 E70 I71 R73 Y76 Q77 N80 G100 K103 K104 K109 L111 G112 E113 S127 K128 S129 Q72I23 25190797 DLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA 4qs3 Q 3.80 BS01 NUC A 1 L2 R5 Y9 R10 K11 Q12 Q13 R14 G15 R16 K22 G24 Y26 F29 W41 Q45 Q46 A49 V52 R56 I66 R67 F69 Y74 T75 K77 E80 R82 M83 G84 K85 G86 K87 R101 I120 H123 K124 L125 P126 K128 K130 Q141 L2 R5 Y9 R10 K11 Q12 Q13 R14 G15 R16 K22 G24 Y26 F29 W41 Q45 Q46 A49 V52 R56 I66 R67 F69 Y74 T75 K77 E80 R82 M83 G84 K85 G86 K87 R101 I120 H123 K124 L125 P126 K128 K130 Q141 Q72I11 25190797 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4qs3 R 3.80 BS01 NUC A 1 R2 H3 L4 K5 S6 R8 K9 L10 N11 R12 H13 S14 S15 H16 R17 A19 L20 N23 Q24 K26 S27 H31 I34 T35 T36 T37 P39 K40 K42 E43 R45 G46 D49 H50 H53 L60 H61 R63 R64 R68 V73 R77 R90 Q91 G92 G93 Y94 T95 R96 L98 K99 R104 R105 G106 D107 V117 R1 H2 L3 K4 S5 R7 K8 L9 N10 R11 H12 S13 S14 H15 R16 A18 L19 N22 Q23 K25 S26 H30 I33 T34 T35 T36 P38 K39 K41 E42 R44 G45 D48 H49 H52 L59 H60 R62 R63 R67 V72 R76 R89 Q90 G91 G92 Y93 T94 R95 L97 K98 R103 R104 G105 D106 V116 Q72I33 25190797 RHLKSGRKLNRHSSHRLALYRNQAKSLLTHGRITTTVPKAKELRGFVDHLIHLAKRGDLHARRLVLRDLQDVKLVRKLFDEIAPRYRDRQGGYTRVLKLAERRRGDGAPLALVELVE 4qs3 S 3.80 BS01 NUC A 1 V14 R15 I18 G22 R23 Q84 F87 Y94 E107 G108 G109 V4 R5 I8 G12 R13 Q74 F77 Y84 E97 G98 G99 Q72I20 25190797 KFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGG 4qs3 S 3.80 BS02 NUC B 1 R17 R25 S27 F29 S31 L32 H34 Y36 Q38 I40 G45 V46 T47 L48 S50 A55 L56 N61 K62 T63 P91 Y92 K93 H95 R7 R15 S17 F19 S21 L22 H24 Y26 Q28 I30 G35 V36 T37 L38 S40 A45 L46 N51 K52 T53 P81 Y82 K83 H85 Q72I20 25190797 KFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGG 4qs3 T 3.80 BS01 NUC A 1 N2 R3 G4 A5 R23 P24 R51 R53 R54 N55 G56 N58 T60 I75 A94 R95 R96 K98 Y100 F101 K113 R115 N2 R3 G4 A5 R23 P24 R51 R53 R54 N55 G56 N58 T60 I75 A94 R95 R96 K98 Y100 F101 K113 R115 Q72JU9 25190797 MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVIRIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLYFIRNLSDREIRRKLRADRKRIDQDRAAERAAKEEAQKA 4qs3 U 3.80 BS01 NUC A 1 P2 R3 A4 K5 T6 V8 R10 R11 R12 K13 H14 K15 K16 K22 G23 Y24 W25 L27 R28 S29 K30 F32 R33 K34 R36 E37 T38 A42 Y45 Y47 H49 R50 K51 R52 R53 K54 R55 D56 F57 R58 R59 W61 I62 V63 N66 R70 N75 Y76 S77 I80 H81 K84 R92 K93 P1 R2 A3 K4 T5 V7 R9 R10 R11 K12 H13 K14 K15 K21 G22 Y23 W24 L26 R27 S28 K29 F31 R32 K33 R35 E36 T37 A41 Y44 Y46 H48 R49 K50 R51 R52 K53 R54 D55 F56 R57 R58 W60 I61 V62 N65 R69 N74 Y75 S76 I79 H80 K83 R91 K92 Q72L76 25190797 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQG 4qs3 V 3.80 BS01 NUC A 1 G8 G9 K10 Q11 L20 E23 K24 R66 K69 K74 K76 A77 K78 Q80 Y81 R83 K84 K85 G86 H87 Q89 G8 G9 K10 Q11 L20 E23 K24 R66 K69 K74 K76 A77 K78 Q80 Y81 R83 K84 K85 G86 H87 Q89 Q72HR2 25190797 MFAIVKTGGKQYRVEPGLKLRVEKLDAEPGATVELPVLLLGGEKTVVGTPVVEGASVVAEVLGHGRGKKILVSKFKAKVQYRRKKGHRQPYTELLIKEIRG 4qs3 W 3.80 BS01 NUC A 1 K4 I6 R8 R11 S13 R15 K16 R18 R25 N40 K41 R42 K49 E52 S53 A56 N57 N61 H62 D77 E78 G79 P80 K83 R84 P87 R88 A89 R90 R92 D94 I95 I96 K97 K98 R99 H102 K4 I6 R8 R11 S13 R15 K16 R18 R25 N40 K41 R42 K49 E52 S53 A56 N57 N61 H62 D77 E78 G79 P80 K83 R84 P87 R88 A89 R90 R92 D94 I95 I96 K97 K98 R99 H102 Q72I09 25190797 MEAKAIARYVRISPRKVRLVVDLIRGKSLEEARNILRYTNKRGAYFVAKVLESAAANAVNNHDMLEDRLYVKAAYVDEGPALKRVLPRARGRADIIKKRTSHITVILGEKHGK 4qs3 Y 3.80 BS01 NUC A 1 R2 V3 M5 V7 K8 S17 G18 K19 K21 V30 L31 P32 Y35 I44 V45 K46 K47 V49 R50 G59 F60 H68 S70 K71 V72 R73 P82 T83 R84 V85 R97 R1 V2 M4 V6 K7 S16 G17 K18 K20 V29 L30 P31 Y34 I43 V44 K45 K46 V48 R49 G58 F59 H67 S69 K70 V71 R72 P81 T82 R83 V84 R96 Q72I15 25190797 RVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCGGALDT 4qs3 Z 3.80 BS01 NUC A 1 R112 Q118 E169 T170 A173 V175 R110 Q116 E167 T168 A171 V173 Q72IA7 25190797 YRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKLAEEA 4qs3 Z 3.80 BS02 NUC B 1 R10 K14 P15 R19 V27 Y29 R31 N34 R72 Q73 N75 K78 H85 D87 F89 R8 K12 P13 R17 V25 Y27 R29 N32 R70 Q71 N73 K76 H83 D85 F87 Q72IA7 25190797 YRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKLAEEA 4qs3 0 3.80 BS01 NUC A 1 A2 K4 R11 N12 R14 D15 S16 Q17 A18 K19 R20 K24 R25 Y26 E27 G28 Q29 R32 A33 G34 N35 I36 R39 R41 G42 T43 R44 F45 K46 G54 R55 D56 F57 T58 F60 L62 F69 L75 R77 A1 K3 R10 N11 R13 D14 S15 Q16 A17 K18 R19 K23 R24 Y25 E26 G27 Q28 R31 A32 G33 N34 I35 R38 R40 G41 T42 R43 F44 K45 G53 R54 D55 F56 T57 F59 L61 F68 L74 R76 Q72HR3 25190797 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPLA 4qs3 1 3.80 BS01 NUC A 1 K3 K10 R11 P12 I13 V14 I18 Q19 R20 R21 K25 R26 E27 V30 K33 T34 T35 I37 R40 Q42 Y43 P44 N45 Q47 V49 R50 R52 R61 A64 S65 H66 P68 K69 R76 G79 L80 K81 K88 K1 K8 R9 P10 I11 V12 I16 Q17 R18 R19 K23 R24 E25 V28 K31 T32 T33 I35 R38 Q40 Y41 P42 N43 Q45 V47 R48 R50 R59 A62 S63 H64 P66 K67 R74 G77 L78 K79 K86 Q72G84 25190797 KVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELL 4qs3 2 3.80 BS01 NUC A 1 K2 L3 R7 L10 R14 N47 H48 I50 R51 K54 R55 I57 A58 R59 L61 T62 N65 R69 K1 L2 R6 L9 R13 N46 H47 I49 R50 K53 R54 I56 A57 R58 L60 T61 N64 R68 Q72I12 25190797 KLSEVRKQLEEARKLSPVELEKLVREKKRELMELRFQASIGQLSQNHKIRDLKRQIARLLTVLNEKRRQNA 4qs3 3 3.80 BS01 NUC A 1 V9 K10 S11 P12 I13 G14 K17 D18 A21 A22 K24 A25 R29 R30 L31 Q32 A42 G45 N46 E48 K49 V9 K10 S11 P12 I13 G14 K17 D18 A21 A22 K24 A25 R29 R30 L31 Q32 A42 G45 N46 E48 K49 Q72I22 25190797 MPRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVAHLVRVEVVE 4qs3 5 3.80 BS01 NUC A 1 A2 K3 H4 P5 V6 P7 K8 K9 K10 T11 S12 K13 A14 R15 R16 A18 R19 R20 H22 H23 T29 L30 V31 P32 P34 K40 P42 H43 Y51 A1 K2 H3 P4 V5 P6 K7 K8 K9 T10 S11 K12 A13 R14 R15 A17 R18 R19 H21 H22 T28 L29 V30 P31 P33 K39 P41 H42 Y50 P62652 25190797 AKHPVPKKKTSKARRDARRSHHALTPPTLVPCPECKAMKPPHTVCPECGYYAGRKVLEV 4qs3 6 3.80 BS01 NUC A 1 V5 R6 K8 E12 R19 Y21 A22 T23 E24 K25 K27 T30 E35 R37 K38 Y39 W42 K45 H46 K53 I54 V1 R2 K4 E8 R15 Y17 A18 T19 E20 K21 K23 T26 E31 R33 K34 Y35 W38 K41 H42 K49 I50 Q72GW3 25190797 VRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVKI 4qs3 7 3.80 BS01 NUC A 1 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 T24 G26 R28 K29 V30 K32 R33 R34 R35 Q36 K37 W40 R41 L42 K48 R49 M1 K2 R3 T4 W5 Q6 P7 N8 R9 R10 K11 R12 A13 K14 H16 G17 F18 R19 R21 T24 G26 R28 K29 V30 K32 R33 R34 R35 Q36 K37 W40 R41 L42 K48 R49 P80340 25190797 MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPAVRKR 4qs3 8 3.80 BS01 NUC A 1 P2 K3 M4 K5 T6 H7 K8 K11 K12 R13 K15 T17 A18 S19 K21 K26 T27 K29 R30 H31 L32 N33 W34 Q35 S37 G38 K39 I41 R42 Q43 R46 F48 K52 E54 L61 L62 P63 P1 K2 M3 K4 T5 H6 K7 K10 K11 R12 K14 T16 A17 S18 K20 K25 T26 K28 R29 H30 L31 N32 W33 Q34 S36 G37 K38 I40 R41 Q42 R45 F47 K51 E53 L60 L61 P62 Q72L77 25190797 PKMKTHKGAKKRVKITASGKVVAMKTGKRHLNWQKSGKEIRQKGRKFVLAKPEAERIKLLLPYE 4qs3 9 3.80 BS01 NUC A 1 M1 K2 V3 R4 A5 S6 V7 K8 V16 R18 R19 H20 R22 Y24 P30 K31 K33 R35 Q36 G37 M1 K2 V3 R4 A5 S6 V7 K8 V16 R18 R19 H20 R22 Y24 P30 K31 K33 R35 Q36 G37 Q72I28 25190797 MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG 4r1s A 1.60 BS01 NAP A 1 G13 G15 G16 F17 I18 R38 K44 D64 L65 T84 A85 S86 P87 V88 T121 S122 S123 Y157 K161 P184 V185 L186 V187 N197 S199 G10 G12 G13 F14 I15 R35 K41 D61 L62 T81 A82 S83 P84 V85 T118 S119 S120 Y154 K158 P181 V182 L183 V184 N194 S196 25217505 VSGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTLCKADLLDYQSLREAINGCDGVFHTASPVTDDPEQMVEPAVIGTKNVINAAAEANVRRVVFTSSIGAVYMDPNRDPETVVDETCWSDPDFCKNTKNWYCYGKMVAEQAAWEEAKEKGVDLVVINPVLVQGPLLQTTVNASVLHILKYLTGSAKTYANSVQAYVDVKDVALAHILLYETPEASGRYLCAESVLHRGDVVEILSKFFPEYPIPTKCSDVTKPRVKPYKFSNQKLKDLGLEFTPVKQCLYETVKSLQEKGHLPIPT 4r1s B 1.60 BS01 NAP B 1 G15 G16 F17 I18 R38 K44 D64 L65 T84 A85 S86 P87 V88 T121 S122 Y157 K161 P184 V185 L186 V187 S199 G12 G13 F14 I15 R35 K41 D61 L62 T81 A82 S83 P84 V85 T118 S119 Y154 K158 P181 V182 L183 V184 S196 25217505 VSGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTLCKADLLDYQSLREAINGCDGVFHTASPVTDDPEQMVEPAVIGTKNVINAAAEANVRRVVFTSSIGAVYMDPNRDPETVVDETCWSDPDFCKNTKNWYCYGKMVAEQAAWEEAKEKGVDLVVINPVLVQGPLLQTTVNASVLHILKYLTGSAKTYANSVQAYVDVKDVALAHILLYETPEASGRYLCAESVLHRGDVVEILSKFFPEYPIPTKCSDVTKPRVKPYKFSNQKLKDLGLEFTPVKQCLYETVKSLQEKGHLPIP 4r1t A 1.70 BS01 I2I A 1 I124 G125 M129 I120 G121 M125 25217505 RSVSGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTLCKADLLDYQSLREAINGCDGVFHTASPVPEQMVEPAVIGTKNVINAAAEANVRRVVFTSSIGAVYMDPNRDPETVVDETCWSDPDFCKNTKNWYCYGKMVAEQAAWEEAKEKGVDLVVINPVLVQGPLLQTTVNASVLHILKYLTGSAKTYANSVQAYVDVKDVALAHILLYETPEASGRYLCAESVLHRGDVVEILSKFFPEYPIPTKCSDVTKPRVKPYKFSNQKLKDLGLEFTPVKQCLYETVKSLQEKGHLPIP 4r1w A 2.41 BS02 COD A 1 S136 G137 F141 G143 F147 H182 I184 A214 E215 P216 N235 S236 F237 G238 M239 T240 G244 P245 D304 I325 R328 I334 G337 N339 S137 G138 F142 G144 F148 H183 I185 A215 E216 P217 N236 S237 F238 G239 M240 T241 G245 P246 D305 I326 R329 I335 G338 N340 Q8AAN6 GMSTQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSSGTTGNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETVNNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEGKAVRVKDLRD 4r1w B 2.41 BS02 COD B 1 S94 G137 T142 G143 F147 H182 I184 A214 E215 P216 N235 S236 F237 G238 M239 T240 G244 P245 D304 I325 R328 G423 K424 S92 G133 T138 G139 F143 H178 I180 A210 E211 P212 N231 S232 F233 G234 M235 T236 G240 P241 D300 I321 R324 G419 K420 Q8AAN6 TQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSSTGNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETVNNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEGKAVRVKDLR 4r1w D 2.41 BS02 COD D 1 S93 S136 G137 F141 F147 H182 I184 A214 E215 P216 N235 S236 F237 G238 M239 T240 G244 P245 D304 I325 R328 G423 K424 S92 S131 G132 F136 F142 H177 I179 A209 E210 P211 N230 S231 F232 G233 M234 T235 G239 P240 D299 I320 R323 G418 K419 Q8AAN6 STQYWEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSLDDIRKIPFTTKSDMRANYPFGLVAGDMKRDGVRIHSSSNPTVIVHSQHDLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAAAGNSKRQIKFISDFKTTALHAIPSYAIRLAEVFQEEGIDPRETTLKTLVIGAEPHTDEQRRKIERMLNVKAYNSFGMTEMNGPGVAFECQEQNGMHFWEDCYLVEIIDPETGEPVPEGEIGELVLTTLDREMMPLIRYRTRDLTRILPGKCPCGRTHLRIDRIKGRSDDMFIIKGVNIFPMQVEKILVQFPELGSNYLITLETVNNQDEMIVEVELSDLSTDNYIELEKIRRDIIRQLKDEILVTPKVKLVKKGSLPQSEGKAVRVKDLRD 4r7x A 2.61 BS01 PO4 A 1 H54 K56 R58 R135 W137 K153 H50 K52 R54 R117 W119 K135 Q96B67 25220262 LGKVKSLTISFDCLNNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNTAYTQNYTEEVEYFNHKDILIGHFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDINTPS 4r7x A 2.61 BS02 PO4 A 2 H50 K139 E141 K151 H46 K121 E123 K133 Q96B67 25220262 LGKVKSLTISFDCLNNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNTAYTQNYTEEVEYFNHKDILIGHFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDINTPS 4r7x A 2.61 BS03 PO4 A 3 K45 H143 P149 K41 H125 P131 Q96B67 25220262 LGKVKSLTISFDCLNNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNTAYTQNYTEEVEYFNHKDILIGHFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDINTPS 4r7x A 2.61 BS04 PO4 A 4 H103 H110 Y112 H85 H92 Y94 Q96B67 25220262 LGKVKSLTISFDCLNNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNTAYTQNYTEEVEYFNHKDILIGHFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDINTPS 4r7x B 2.61 BS02 PO4 B 2 H54 K56 R135 W137 K153 H49 K51 R116 W118 K134 Q96B67 25220262 LGKVKSLTISFDCLNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNNTAYTQNYTEEVEYFNHKDILIGFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDINTPS 4r7x B 2.61 BS03 PO4 B 3 R52 K139 K153 R47 K120 K134 Q96B67 25220262 LGKVKSLTISFDCLNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNNTAYTQNYTEEVEYFNHKDILIGFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDINTPS 4r82 A 1.66 BS01 NAD A 1 R21 F24 G25 N47 H143 F164 G167 R14 F17 G18 N40 H132 F153 G156 Q8GME2 PAELVDPKDRVQLRRVFGDFPTGVTVVTVGGSEPRGMTANSFTSVSLSPPLVLICVGKDAVMHQRLTALPTFAVSVLEAGQEKAARHFADHSVDQFDTVDWVLGEESGAPLIAGAVAHLECAIHRLYEGGDHTIFLGEVITATRWPAREGMLFSGGRFRRFAPDAD 4r82 A 1.66 BS02 NAD A 2 R21 H143 R14 H132 Q8GME2 PAELVDPKDRVQLRRVFGDFPTGVTVVTVGGSEPRGMTANSFTSVSLSPPLVLICVGKDAVMHQRLTALPTFAVSVLEAGQEKAARHFADHSVDQFDTVDWVLGEESGAPLIAGAVAHLECAIHRLYEGGDHTIFLGEVITATRWPAREGMLFSGGRFRRFAPDAD 4r82 A 1.66 BS03 MG A 1 F49 T50 F42 T43 Q8GME2 PAELVDPKDRVQLRRVFGDFPTGVTVVTVGGSEPRGMTANSFTSVSLSPPLVLICVGKDAVMHQRLTALPTFAVSVLEAGQEKAARHFADHSVDQFDTVDWVLGEESGAPLIAGAVAHLECAIHRLYEGGDHTIFLGEVITATRWPAREGMLFSGGRFRRFAPDAD 4r82 A 1.66 BS04 FAD A 1 M44 T45 A46 N47 S48 C62 V63 G64 A67 A96 H98 F164 F169 M37 T38 A39 N40 S41 C55 V56 G57 A60 A89 H91 F153 F158 Q8GME2 PAELVDPKDRVQLRRVFGDFPTGVTVVTVGGSEPRGMTANSFTSVSLSPPLVLICVGKDAVMHQRLTALPTFAVSVLEAGQEKAARHFADHSVDQFDTVDWVLGEESGAPLIAGAVAHLECAIHRLYEGGDHTIFLGEVITATRWPAREGMLFSGGRFRRFAPDAD 4r82 B 1.66 BS02 NAD B 1 R21 F24 G25 N47 H143 G167 R13 F16 G17 N39 H131 G155 Q8GME2 AELVDPKDRVQLRRVFGDFPTGVTVVTVGGSEPRGMTANSFTSVSLSPPLVLICVGKDAVMHQRLTALPTFAVSVLEAGQEKAARHFADHSVDQFDTVDWVLGEESGAPLIAGAVAHLECAIHRLYEGGDHTIFLGEVITATRWPAREGMLFSGGRFRRFAPDAD 4r82 B 1.66 BS04 CA B 1 P157 R159 P145 R147 Q8GME2 AELVDPKDRVQLRRVFGDFPTGVTVVTVGGSEPRGMTANSFTSVSLSPPLVLICVGKDAVMHQRLTALPTFAVSVLEAGQEKAARHFADHSVDQFDTVDWVLGEESGAPLIAGAVAHLECAIHRLYEGGDHTIFLGEVITATRWPAREGMLFSGGRFRRFAPDAD 4r82 B 1.66 BS05 FAD B 1 M44 T45 A46 N47 S48 C62 V63 G64 A67 V68 A96 F164 F169 M36 T37 A38 N39 S40 C54 V55 G56 A59 V60 A88 F152 F157 Q8GME2 AELVDPKDRVQLRRVFGDFPTGVTVVTVGGSEPRGMTANSFTSVSLSPPLVLICVGKDAVMHQRLTALPTFAVSVLEAGQEKAARHFADHSVDQFDTVDWVLGEESGAPLIAGAVAHLECAIHRLYEGGDHTIFLGEVITATRWPAREGMLFSGGRFRRFAPDAD 4rbo A 3.30 BS01 NUC B 1 Y119 Y136 K140 Q144 R147 M148 K151 Y20 Y37 K41 Q45 R48 M49 K52 Q6NSW7 TVFSSTQLCVLNDRFQRQKYLSLQQMQELSNILNLSYKQVKTWFQNQRMKSKRWQ 4rbo A 3.30 BS02 NUC C 1 T100 F102 K137 Q138 T141 W142 N145 T1 F3 K38 Q39 T42 W43 N46 Q6NSW7 TVFSSTQLCVLNDRFQRQKYLSLQQMQELSNILNLSYKQVKTWFQNQRMKSKRWQ 4rbo D 3.30 BS01 NUC E 1 Y119 L122 M125 Y136 Q144 R147 M148 K151 Y20 L23 M26 Y37 Q45 R48 M49 K52 Q6NSW7 TVFSSTQLCVLNDRFQRQKYLSLQQMQELSNILNLSYKQVKTWFQNQRMKSKRW 4rdc A 1.20 BS01 PRO A 1 L70 L131 S132 S153 N154 T155 F204 D280 F331 L18 L79 S80 S101 N102 T103 F152 D228 F279 Q3MFZ5 NTIPIGIALAQTSNVALLGQEQVAGAKIAEKYFNDKGGVNGTPIKLIFQDTAGDEAGTINAFQTLINKDKVVGIVGPTLSQQAFSANPIAERAKVPVVGPSNTAKGIPEIGDYVARVSAPVSVVAPNSVKAALKQNPNIKKVAVFFAQNDAFSKSETEIFQQTVKDQGLELVTVQKFQTTDTDFQSQATNAINLKPDLVIISGLAADGGNLVRQLRELGYQGAIIGGDGLNTSNVFAVCKALCDGVLIAQAYSPEYTGEINKAFRQAYVDQYKKEPPQFSAQAFAAVQVYVESLKALDTKNKVSKIQLPELRTELNKQLLTGKYNTPLGEISFTPIGEVVQKDFYVAQIKMEKDGSQGKFTFLK 4tkv A 1.50 BS01 ICE A 1 V70 R96 Y229 I231 C275 I355 G356 G357 L358 R359 F381 H442 V67 R93 Y226 I228 C272 I352 G353 G354 L355 R356 F378 H439 1.18.6.1 P07328 MSREEVESLIQEVLEVYPEKARKDRNKHLAVNDPAVTQSKKCIISNKKSQPGLMTIRGCAYAGSKGVVWGPIKDMIHISHGPVGCGQYSRAGRRNYYIGTTGVNAFVTMNFTSDFQEKDIVFGGDKKLAKLIDEVETLFPLNKGISVQSECPIGLIGDDIESVSKVKGAELSKTIVPVRCEGFRGVSQSLGHHIANDAVRDWVLGKRDEDTTFASTPYDVAIIGDYNIGGDAWSSRILLEEMGLRCVAQWSGDGSISEIELTPKVKLNLVHCYRSMNYISRHMEEKYGIPWMEYNFFGPTKTIESLRAIAAKFDESIQKKCEEVIAKYKPEWEAVVAKYRPRLEGKRVMLYIGGLRPRHVIGAYEDLGMEVVGTGYEFAHNDDYDRTMKEMGDSTLLYDDVTGYEFEEFVKRIKPDLIGSGIKEKFIFQKMGIPFRQMHSWDYSGPYHGFDGFAIFARDMDMTLNNPCWKKLQAPWE 4tkv A 1.50 BS02 ICE A 2 R93 T104 T111 M112 R90 T101 T108 M109 1.18.6.1 P07328 MSREEVESLIQEVLEVYPEKARKDRNKHLAVNDPAVTQSKKCIISNKKSQPGLMTIRGCAYAGSKGVVWGPIKDMIHISHGPVGCGQYSRAGRRNYYIGTTGVNAFVTMNFTSDFQEKDIVFGGDKKLAKLIDEVETLFPLNKGISVQSECPIGLIGDDIESVSKVKGAELSKTIVPVRCEGFRGVSQSLGHHIANDAVRDWVLGKRDEDTTFASTPYDVAIIGDYNIGGDAWSSRILLEEMGLRCVAQWSGDGSISEIELTPKVKLNLVHCYRSMNYISRHMEEKYGIPWMEYNFFGPTKTIESLRAIAAKFDESIQKKCEEVIAKYKPEWEAVVAKYRPRLEGKRVMLYIGGLRPRHVIGAYEDLGMEVVGTGYEFAHNDDYDRTMKEMGDSTLLYDDVTGYEFEEFVKRIKPDLIGSGIKEKFIFQKMGIPFRQMHSWDYSGPYHGFDGFAIFARDMDMTLNNPCWKKLQAPWE 4tkv B 1.50 BS01 ICE A 3 F450 R453 F449 R452 1.18.6.1 P07329 SQQVDKIKASYPLFLDQDYKDMLAKKRDGFEEKYPQDKIDEVFQWTTTKEYQELNFQREALTVNPAKACQPLGAVLCALGFEKTMPYVHGSQGCVAYFRSYFNRHFREPVSCVSDSMTEDAAVFGGQQNMKDGLQNCKATYKPDMIAVSTTCMAEVIGDDLNAFINNSKKEGFIPDEFPVPFAHTPSFVGSHVTGWDNMFEGIARYFTLKSMDDKVVGSNKKINIVPGFETYLGNFRVIKRMLSEMGVGYSLLSDPEEVLDTPADGQFRMYAGGTTQEEMKDAPNALNTVLLQPWHLEKTKKFVEGTWKHEVPKLNIPMGLDWTDEFLMKVSEISGQPIPASLTKERGRLVDMMTDSHTWLHGKRFALWGDPDFVMGLVKFLLELGCEPVHILCHNGNKRWKKAVDAILAASPYGKNATVYIGKDLWHLRSLVFTDKPDFMIGNSYGKFIQRDTLHKGKEFEVPLIRIGFPIFDRHHLHRSTTLGYEGAMQILTTLVNSILERLDEETRGMQATDYNHDLVR 4tnp A 2.00 BS01 DCP A 1 Q149 L150 R164 R206 H210 H215 H233 K312 Y315 D319 R366 H370 Y374 Q375 Q36 L37 R51 R93 H97 H102 H120 K192 Y195 D199 R246 H250 Y254 Q255 3.1.5.- Q9Y3Z3 TMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4tnp A 2.00 BS04 DCP A 3 R333 R352 K354 N358 K523 R213 R232 K234 N238 K403 3.1.5.- Q9Y3Z3 TMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4tnp B 2.00 BS04 GTP B 1 Y155 V156 V378 R451 Y43 V44 V259 R332 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4tnp B 2.00 BS06 DCP D 1 R333 F337 R352 K354 K523 R214 F218 R233 K235 K404 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4tnp D 2.00 BS02 GTP A 1 K116 V117 I118 I136 D137 Q142 R145 F165 K4 V5 I6 I24 D25 Q30 R33 F53 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLESPVLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4tnq A 2.55 BS01 TTP A 1 Q149 L150 R164 R206 H210 H215 D311 K312 Y315 D319 R366 Y374 Q375 Q36 L37 R51 R93 H97 H102 D193 K194 Y197 D201 R248 Y256 Q257 3.1.5.- Q9Y3Z3 TMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLESLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEW 4tnr D 2.75 BS01 DTP D 1 Q149 L150 R164 R206 N207 H210 H215 D311 K312 Y315 D319 R366 H370 Y374 Q375 Q37 L38 R52 R94 N95 H98 H103 D193 K194 Y197 D201 R248 H252 Y256 Q257 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4tnx A 2.31 BS04 3PO A 1 R164 R206 N207 H210 H215 H233 D311 K312 Y315 R366 R52 R94 N95 H98 H103 H121 D193 K194 Y197 R248 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4tnx B 2.31 BS02 DGT B 1 D330 R333 R352 K354 N358 K523 D211 R214 R233 K235 N239 K404 3.1.5.- Q9Y3Z3 TMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEW 4tnz D 2.38 BS05 DTP D 1 R333 F337 R352 K354 N358 R215 F219 R234 K236 N240 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEW 4to2 C 2.27 BS05 MG C 1 D309 K312 D191 K194 3.1.5.- Q9Y3Z3 DTMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLELWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4to5 C 2.80 BS03 DCP C 1 Q149 R164 R206 H210 H215 H233 D311 K312 Y315 D319 R366 H370 Y374 Q375 Q36 R51 R93 H97 H102 H120 D191 K192 Y195 D199 R246 H250 Y254 Q255 3.1.5.- Q9Y3Z3 TMKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCRNLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDICFIKEQIVGPLLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWN 4tr0 A 1.95 BS01 GDS A 1 Y11 C12 P13 Y14 T52 V53 P54 G65 C66 D67 Y11 C12 P13 Y14 T52 V53 P54 G65 C66 D67 A8MJH2 25218089 MKNITIYTKNYCPYCKKAVSLLSSKGVDFKEVDVTHDSKAFEDVMAKTGWDTVPQVFVDEEFLGGCDDIHALDRQGILDKKLGLKLEHHHHH 4tup A 1.80 BS02 NUC P 1 S104 G105 I106 G107 P108 S109 A110 K232 R251 D253 R255 S98 G99 I100 G101 P102 S103 A104 K226 R245 D247 R249 2.7.7.7,4.2.99.- P06746 PQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4tur A 2.17 BS01 NUC T 1 H34 S229 K230 G231 E232 T233 K234 Y271 R283 E295 Y296 H28 S221 K222 G223 E224 T225 K226 Y263 R275 E287 Y288 2.7.7.7,4.2.99.- P06746 PQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4tus A 2.42 BS01 NUC T 1 H34 S229 K230 G231 E232 T233 K234 Y271 N279 K280 R283 H25 S220 K221 G222 E223 T224 K225 Y261 N269 K270 R273 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4tus A 2.42 BS02 NUC P 1 S104 G105 G107 P108 S109 A110 D192 R254 D256 S95 G96 G98 P99 S100 A101 D183 R244 D246 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4tus A 2.42 BS03 NUC D 1 K35 A38 Y39 L62 G64 V65 G66 K68 I69 K26 A29 Y30 L53 G55 V56 G57 K59 I60 2.7.7.7,4.2.99.- P06746 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 4u3b A 1.34 BS03 3BW A 1 I18 H19 H58 E73 H74 T179 F180 A181 I186 I189 G195 G198 S199 T203 V205 H226 K227 D230 H253 I17 H18 H57 E72 H73 T178 F179 A180 I185 I188 G194 G197 S198 T202 V204 H225 K226 D229 H252 3.5.1.- O67648 GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK 4u3d A 1.25 BS03 3BX A 1 I18 H58 E73 H74 T179 F180 A181 I186 I189 G198 S199 T203 V205 Y212 H226 K227 D230 H253 I17 H57 E72 H73 T178 F179 A180 I185 I188 G197 S198 T202 V204 Y211 H225 K226 D229 H252 3.5.1.- O67648 GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK 4u8h A 2.80 BS01 ZN A 1 C432 H491 C412 H471 Q9R194 25127877 ASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLS 4u8h B 2.80 BS01 ZN A 1 C1210 C1213 C75 C78 O54943 25127877 KYVLQDPIWLLMANTDDSIMMTYQLPSRDLQAVLKEDQEKLKLLQRSQPRFTEGQRRELREVHPWLPTAIDVTGCVYCE 4u8h D 2.80 BS01 ZN D 1 C1210 Y1212 C1213 C75 Y77 C78 O54943 25127877 KYVLQDPIWLLMANTDDSIMMTYQLPSRDLQAVLKEDQEKLKLLQRSQPRFTEGQRRELREVHPWLPTAIDVTGCVYCE 4u99 A 2.00 BS01 HEM A 1 M1 K2 I4 I5 F74 L77 H81 V84 V85 L94 I98 I102 H103 V106 Y110 P113 S114 L115 P116 I118 Y132 S134 R136 L138 C141 A142 L145 L146 A149 M1 K2 I4 I5 F74 L77 H81 V84 V85 L94 I98 I102 H103 V106 Y110 P113 S114 L115 P116 I118 Y132 S134 R136 L138 C141 A142 L145 L146 A149 Q8EF49 MKGIIFNVLEDMVVAQCGMSVWNELLEKHAPKDRVYVSAKSYAESELFSIVQDVAQRLNMPIQDVVKAFGQFLFNGLASRHTDVVDKFDDFTSLVMGIHDVIHLEVNKLYHEPSLPHINGQLLPNNQIALRYSSPRRLCFCAEGLLFGAAQHFAAAIQISHDTCMHTGADHCMLIIELQNDENLYFQ 4u99 A 2.00 BS02 ZN A 1 C139 H161 C164 C172 C139 H161 C164 C172 Q8EF49 MKGIIFNVLEDMVVAQCGMSVWNELLEKHAPKDRVYVSAKSYAESELFSIVQDVAQRLNMPIQDVVKAFGQFLFNGLASRHTDVVDKFDDFTSLVMGIHDVIHLEVNKLYHEPSLPHINGQLLPNNQIALRYSSPRRLCFCAEGLLFGAAQHFAAAIQISHDTCMHTGADHCMLIIELQNDENLYFQ 4u9b A 1.65 BS02 NO A 1 I98 L115 I98 L115 Q8EF49 MKGIIFNVLEDMVVAQCGMSVWNELLEKHAPKDRVYVSAKSYAESELFSIVQDVAQRLNMPIQDVVKAFGQFLFNGLASRHTDVVDKFDDFTSLVMGIHDVIHLEVNKLYHEPSLPHINGQLLPNNQIALRYSSPRRLCFCAEGLLFGAAQHFQQKIQISHDTCMHTGADHCMLIIELQN 4u9k A 2.45 BS03 NO A 1 L73 L77 L145 L73 L77 L145 Q8EF49 MKGIIFNVLEDMVVAQCGMSVWNELLEKHAPKDRVYVSAKSYAESELFSIVQDVAQRLNMPIQDVVKAFGQFLFNGLASRHTDVVDKFDDFTSLVMGIHDVIHLEVNKLYHEPSLPHINGQLLPNNQIALRYSSPRRLCFCAEGLLFGAAQHFAAAIQISHDTCMHTGADHCMLIIELQNDENLYFQ 4uq8 B 4.95 BS01 SF4 B 1 G53 C54 C55 G90 G117 G118 C119 C149 G150 G27 C28 C29 G64 G91 G92 C93 C123 G124 25209663 GGGGGGGGGGGGGGGGGGGGGGGGGGGCCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGGGGGGGGGGGGGGGGGGG 4uq8 E 4.95 BS01 FES E 1 C103 G105 G107 C108 C144 G145 G146 G147 C148 C84 G86 G88 C89 C125 G126 G127 G128 C129 25209663 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 4uq8 F 4.95 BS01 SF4 F 1 G358 C359 G360 G361 C362 C365 G404 C405 G408 G328 C329 G330 G331 C332 C335 G374 C375 G378 25209663 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGCGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 4uq8 G 4.95 BS01 SF4 G 1 H101 G104 C105 C108 G110 C114 G117 G205 H94 G97 C98 C101 G103 C107 G110 G188 25209663 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGGGGGGGGGCGGCGGGGGGGGGGGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGHGGGCGGCGGGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGCGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 4uq8 G 4.95 BS02 SF4 G 2 C153 G154 G155 C156 G158 C159 C203 G207 C136 G137 G138 C139 G141 C142 C186 G190 25209663 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGGGGGGGGGCGGCGGGGGGGGGGGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGHGGGCGGCGGGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGCGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 4uq8 G 4.95 BS03 FES G 1 G40 C41 G49 G51 C52 G53 G54 C55 C69 G33 C34 G42 G44 C45 G46 G47 C48 C62 25209663 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGGGGGGGGGCGGCGGGGGGGGGGGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGHGGGCGGCGGGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGCGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 4uq8 I 4.95 BS01 SF4 I 1 C87 G89 C116 G117 G118 C119 G120 G121 C122 C73 G75 C102 G103 G104 C105 G106 G107 C108 25209663 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGCGGCGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGCGGCGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 4uq8 I 4.95 BS02 SF4 I 2 C77 G78 G79 C80 G81 G82 C83 C126 G130 C63 G64 G65 C66 G67 G68 C69 C112 G116 25209663 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGCGGCGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGCGGCGGCGGGCGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 4usq A 2.39 BS01 FAD A 1 G20 G21 G22 Q23 A24 D43 A44 E45 G50 A51 W52 W56 L61 F62 V107 W108 V109 A136 T137 G138 R141 S183 G328 A338 T339 L340 G8 G9 G10 Q11 A12 D31 A32 E33 G38 A39 W40 W44 L49 F50 V95 W96 V97 A124 T125 G126 R129 S171 G301 A311 T312 L313 1.14.13.8 I3IEE4 STDIVIIGGGQAALSVAYYLRRSKYSFVMLDAEQTPGGAWLHGWDSLRLFSPSTWSSLSGWQMPPTGETYPSRDQVVDYLRHYESRYEFPVQRPVWVSAVNNLGDRLEVVSERQQWRARVVISATGTWRNPFIPAYPGADLFQGAQLHSAHYQSPAPFAGQKVLVVGGGNSGAQILAEVSRVADCTWVTTSEPIFLPDDVDGRVLFQRATDRWKADVVMVPPVKEARERGALHAVRPFTRFTANGVVWADGTGSAVDAVIWCTGFRPALAHLQSLGVINPDGKVDLAGTRSLQEPRLWLLGYGEWTGLASATLIGVGRSARATAEEIIQYLDS 4usr A 1.83 BS01 FAD A 1 G11 G12 G13 Q14 A15 L33 D34 E35 Q36 G41 A42 W43 W47 L50 L52 F53 V99 V101 A128 T129 G130 S175 G320 A330 T331 L332 G14 G15 G16 Q17 A18 L36 D37 E38 Q39 G44 A45 W46 W50 L53 L55 F56 V102 V104 A131 T132 G133 S178 G323 A333 T334 L335 1.14.13.8 M2V3J0 GPAMPPILDVIVIGGGQAALTTAYFLRRTSLSYLLLDEQPGPGGAWLHAWDSLRLFSPAAWSSIAGWPMPSPTEPGNPTRNDVIDYLRRYEDRYQFPIQRPVRVDTVTRLDDLWRVQAGDQQWLARAVISATGTWSKPFIPPYEGRELFQGAQIHSAHYRTPAPFAGKRVMVVGGGNSGAQVLAELSSVSETLWITQEPPAFLPDEVDGRVLFERATARWKAQQEGRSIDEPAGGFGDIVMVPPVREARERGVLVAERPFARFTETGVEWADGRRENLDAVIWCSGFRPALDHLRELGVVEADGKVQVEDTRVVKQPNLWLVGYGDWTGMASATLIGVTRTARSTADQVVQALTATP 4uu0 A 2.50 BS01 TG1 A 1 L253 E255 F256 Q259 L260 V263 I267 A306 I761 I765 N768 V769 V772 L828 I829 F834 M838 L253 E255 F256 Q259 L260 V263 I267 A306 I761 I765 N768 V769 V772 L828 I829 F834 M838 3.6.3.8 B6CAM1 25103814 MEAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDFCSLNEFSITGSTYAPEGEVLKNDKPIRSGQFDGLVELATICALCNDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPVKEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSSRFMEYETDLTFVGVVGMLDPPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFMYAEDGPGVTYHQLTHFMQCTEDHPHFEGLDCEIFEAPEPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLKALDLTQWLMVLKISLPVIGLDEILKFIARNYLEG 4uu1 A 2.80 BS01 TG1 A 1 E255 F256 L260 V263 A306 I761 I765 V769 V772 L828 I829 F834 Y837 M838 E255 F256 L260 V263 A306 I761 I765 V769 V772 L828 I829 F834 Y837 M838 3.6.3.8 B6CAM1 25103814 MEAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDFCSLNEFSITGSTYAPEGEVLKNDKPIRSGQFDGLVELATICALCNDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPVKEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSSRFMEYETDLTFVGVVGMLDPPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFMYAEDGPGVTYHQLTHFMQCTEDHPHFEGLDCEIFEAPEPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLKALDLTQWLMVLKISLPVIGLDEILKFIARNYLEG 4uu1 A 2.80 BS02 PCW A 1 N101 V104 Q108 Q250 P312 A313 I315 T316 L319 P337 N101 V104 Q108 Q250 P312 A313 I315 T316 L319 P337 3.6.3.8 B6CAM1 25103814 MEAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDFCSLNEFSITGSTYAPEGEVLKNDKPIRSGQFDGLVELATICALCNDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPVKEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSSRFMEYETDLTFVGVVGMLDPPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFMYAEDGPGVTYHQLTHFMQCTEDHPHFEGLDCEIFEAPEPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLKALDLTQWLMVLKISLPVIGLDEILKFIARNYLEG 4uu1 A 2.80 BS03 PCW A 2 M923 R924 F986 N990 M923 R924 F986 N990 3.6.3.8 B6CAM1 25103814 MEAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDFCSLNEFSITGSTYAPEGEVLKNDKPIRSGQFDGLVELATICALCNDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPVKEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSSRFMEYETDLTFVGVVGMLDPPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFMYAEDGPGVTYHQLTHFMQCTEDHPHFEGLDCEIFEAPEPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLKALDLTQWLMVLKISLPVIGLDEILKFIARNYLEG 4uu1 A 2.80 BS04 PCW A 3 L273 N275 A780 L781 L273 N275 A780 L781 3.6.3.8 B6CAM1 25103814 MEAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDFCSLNEFSITGSTYAPEGEVLKNDKPIRSGQFDGLVELATICALCNDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPVKEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSSRFMEYETDLTFVGVVGMLDPPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFMYAEDGPGVTYHQLTHFMQCTEDHPHFEGLDCEIFEAPEPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLKALDLTQWLMVLKISLPVIGLDEILKFIARNYLEG 4uu1 A 2.80 BS05 ACP A 1 E442 F487 K515 G516 A517 R560 L562 G626 E442 F487 K515 G516 A517 R560 L562 G626 3.6.3.8 B6CAM1 25103814 MEAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDFCSLNEFSITGSTYAPEGEVLKNDKPIRSGQFDGLVELATICALCNDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPVKEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSSRFMEYETDLTFVGVVGMLDPPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFMYAEDGPGVTYHQLTHFMQCTEDHPHFEGLDCEIFEAPEPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLKALDLTQWLMVLKISLPVIGLDEILKFIARNYLEG 4ux8 A 24.00 BS01 CA A 1 E178 D264 E265 D267 D302 E143 D226 E227 D229 D264 2.7.10.1 P07949 25242331 LYFSRDAYWEKLYVDQAAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWIRIQEDTGLLYLQRSLDHSSWEKLSVRNRGFPLLTVYLKVFLSPCQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENRPPGTFHQFRLLPVQFLCPQISVAYRLLEGEGLPFRSAPDSLEVSTRWALDREQREKYELVAVCTVHREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNRNLSISENRTMQLAVLVNDSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSY 4ux8 A 24.00 BS02 CA A 2 E178 D230 R231 E232 D267 E143 D195 R196 E197 D229 2.7.10.1 P07949 25242331 LYFSRDAYWEKLYVDQAAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWIRIQEDTGLLYLQRSLDHSSWEKLSVRNRGFPLLTVYLKVFLSPCQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENRPPGTFHQFRLLPVQFLCPQISVAYRLLEGEGLPFRSAPDSLEVSTRWALDREQREKYELVAVCTVHREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNRNLSISENRTMQLAVLVNDSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSY 4ux8 A 24.00 BS03 CA A 3 D266 S268 D300 D302 G308 E309 R360 D228 S230 D262 D264 G270 E271 R322 2.7.10.1 P07949 25242331 LYFSRDAYWEKLYVDQAAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWIRIQEDTGLLYLQRSLDHSSWEKLSVRNRGFPLLTVYLKVFLSPCQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENRPPGTFHQFRLLPVQFLCPQISVAYRLLEGEGLPFRSAPDSLEVSTRWALDREQREKYELVAVCTVHREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNRNLSISENRTMQLAVLVNDSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSY 4uxu A 1.71 BS01 MLK A 1 Y95 N96 S150 W151 T152 Y153 Y199 D201 Y93 N94 S148 W149 T150 Y151 Y197 D199 Q9UGM1 GKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDVEWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRRS 4uxu B 1.71 BS01 MLK B 1 Y95 S150 W151 T152 Y153 Y199 D201 Y93 S148 W149 T150 Y151 Y197 D199 Q9UGM1 GKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDVEWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRRS 4w2a B 3.60 BS01 NUC A 1 K22 W24 P26 R96 L98 G99 G100 T103 N104 T107 I108 R111 K133 Y148 I172 E176 K179 K19 W21 P23 R93 L95 G96 G97 T100 N101 T104 I105 R108 K130 Y145 I169 E173 K176 P80371 25198768 EITVKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ 4w2a D 3.60 BS01 NUC A 1 G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 G23 E24 R25 R35 R36 Y38 P40 G41 Q42 H43 Q45 R49 S52 Y54 A55 L58 R59 K61 Q62 R65 R66 S71 E72 R73 Q74 R76 N77 K85 K86 V112 S113 R115 Q116 R118 Q119 R122 H123 H125 R131 R132 V133 D134 L135 S137 Y138 K151 L155 E156 E205 S208 R209 G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 G22 E23 R24 R34 R35 Y37 P39 G40 Q41 H42 Q44 R48 S51 Y53 A54 L57 R58 K60 Q61 R64 R65 S70 E71 R72 Q73 R75 N76 K84 K85 V111 S112 R114 Q115 R117 Q118 R121 H122 H124 R130 R131 V132 D133 L134 S136 Y137 K150 L154 E155 E204 S207 R208 P80373 25198768 GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR 4w2a E 3.60 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 F45 P49 K57 Y60 Y61 G85 A86 K92 A95 T98 I101 A102 L119 T120 K121 E122 L123 S125 R126 N127 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 F41 P45 K53 Y56 Y57 G81 A82 K88 A91 T94 I97 A98 L115 T116 K117 E118 L119 S121 R122 N123 N126 Y129 Q5SHQ5 25198768 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKGE 4w2a H 3.60 BS01 NUC A 1 A2 R3 R4 R6 A7 R10 L12 N28 K29 I30 M31 D33 G34 K35 K36 N37 L38 R41 I42 R79 R94 S98 R102 R114 R115 A116 R119 W156 A1 R2 R3 R5 A6 R9 L11 N27 K28 I29 M30 D32 G33 K34 K35 N36 L37 R40 I41 R78 R93 S97 R101 R113 R114 A115 R118 W155 P17291 25198768 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4w2a H 3.60 BS02 NUC X 1 N84 Q86 R143 A147 N148 N83 Q85 R142 A146 N147 P17291 25198768 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4w2a I 3.60 BS01 NUC A 1 M1 T3 D4 D8 T11 R12 R14 N15 V19 K21 A28 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 G96 V97 S113 T114 S115 V129 G130 E132 M1 T3 D4 D8 T11 R12 R14 N15 V19 K21 A28 S29 R30 F31 K56 R75 K88 P89 G90 R91 R92 Y94 G96 V97 S113 T114 S115 V129 G130 E132 Q5SHQ2 25198768 MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW 4w2a J 3.60 BS01 NUC A 1 E2 Q3 Y5 T7 R9 R10 K11 E12 V14 R16 F18 R20 Y36 Q38 Y62 R66 G67 G68 G69 K70 S71 G72 Q73 R83 R93 K97 L102 T103 R104 R107 V108 V109 E110 R111 K112 K113 Y114 G115 H117 K118 R120 R121 A122 P123 Q124 Y125 S126 K127 R128 E1 Q2 Y4 T6 R8 R9 K10 E11 V13 R15 F17 R19 Y35 Q37 Y61 R65 G66 G67 G68 K69 S70 G71 Q72 R82 R92 K96 L101 T102 R103 R106 V107 V108 E109 R110 K111 K112 Y113 G114 H116 K117 R119 R120 A121 P122 Q123 Y124 S125 K126 R127 P80374 25198768 EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGHFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR 4w2a K 3.60 BS01 NUC A 1 R5 K7 R9 H13 K14 D17 S35 G36 P37 I38 P39 L40 P41 T42 R43 V44 R45 T48 R51 G52 P53 F54 K55 H56 K57 S59 R60 H62 H68 R70 D73 K99 R3 K5 R7 H11 K12 D15 S33 G34 P35 I36 P37 L38 P39 T40 R41 V42 R43 T46 R49 G50 P51 F52 K53 H54 K55 S57 R58 H60 H66 R68 D71 K97 Q5SHN7 25198768 KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKTV 4w2a L 3.60 BS01 NUC A 1 Y20 H22 N26 N27 I29 T31 G37 N38 P39 W42 S44 G46 G52 S53 K55 R85 P113 V114 P115 H116 N117 G118 C119 R120 K122 K123 K124 Y10 H12 N16 N17 I19 T21 G27 N28 P29 W32 S34 G36 G42 S43 K45 R75 P103 V104 P105 H106 N107 G108 C109 R110 K112 K113 K114 P80376 25198768 KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS 4w2a M 3.60 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 K13 R15 E16 K17 K20 K21 K23 K28 G29 A30 P31 F32 R33 R34 P45 K46 K47 N49 S50 A51 L52 R53 K54 K57 T61 Y69 P71 G72 E73 G74 R86 G87 G88 R89 V90 K91 D92 P94 G95 R97 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 K9 R11 E12 K13 K16 K17 K19 K24 G25 A26 P27 F28 R29 R30 P41 K42 K43 N45 S46 A47 L48 R49 K50 K53 T57 Y65 P67 G68 E69 G70 R82 G83 G84 R85 V86 K87 D88 P90 G91 R93 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 Q5SHN3 25198768 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEAA 4w2a N 3.60 BS01 NUC A 1 K13 R14 Y21 I22 Y23 G24 I25 G26 K27 A28 R29 R44 V74 N77 Y87 R88 R91 H92 L96 P97 V98 R99 G100 Q101 R102 T103 R104 T105 N106 A107 R108 T109 R110 K111 P113 R114 K115 T116 V117 K121 K12 R13 Y20 I21 Y22 G23 I24 G25 K26 A27 R28 R43 V73 N76 Y86 R87 R90 H91 L95 P96 V97 R98 G99 Q100 R101 T102 R103 T104 N105 A106 R107 T108 R109 K110 P112 R113 K114 T115 V116 K120 P80377 25198768 ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKK 4w2a P 3.60 BS01 NUC A 1 P2 K5 K8 Q9 I12 F18 D21 T22 G23 S24 T25 Q28 L31 R35 L39 H42 H46 K48 D49 H50 H51 S52 R54 G55 M58 M59 G61 R64 R65 R68 Y69 R72 P1 K4 K7 Q8 I11 F17 D20 T21 G22 S23 T24 Q27 L30 R34 L38 H41 H45 K47 D48 H49 H50 S51 R53 G54 M57 M58 G60 R63 R64 R67 Y68 R71 Q5SJ76 25198768 PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG 4w2a Q 3.60 BS01 NUC A 1 M1 K3 R5 L6 R8 F9 G10 K12 H13 N14 P15 H16 Y17 R18 D23 A24 R25 K27 R28 G30 K31 Y32 K35 Y38 P41 R42 K43 T44 Y58 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 M1 K3 R5 L6 R8 F9 G10 K12 H13 N14 P15 H16 Y17 R18 D23 A24 R25 K27 R28 G30 K31 Y32 K35 Y38 P41 R42 K43 T44 Y58 W59 S61 V62 G63 Q65 T67 D68 T69 R72 R75 F80 R81 Q82 Q5SJH3 25198768 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQEA 4w2a S 3.60 BS01 NUC A 1 K49 I50 P52 R53 R54 K61 Q63 R64 A67 K68 K71 R72 R74 I75 F81 T82 K31 I32 P34 R35 R36 K43 Q45 R46 A49 K50 K53 R54 R56 I57 F63 T64 Q5SLQ0 25198768 KAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVRK 4w2a U 3.60 BS01 NUC A 1 L10 K14 R15 H16 R17 Q18 S19 K21 R22 R23 N26 K27 A28 K29 S31 A32 K34 T35 K38 K39 K54 I55 R57 E60 S61 D64 K65 K68 S70 K74 N75 A78 R79 R80 K81 S82 R83 M85 R86 R89 G101 G103 L104 S105 L3 K7 R8 H9 R10 Q11 S12 K14 R15 R16 N19 K20 A21 K22 S24 A25 K27 T28 K31 K32 K47 I48 R50 E53 S54 D57 K58 K61 S63 K67 N68 A71 R72 R73 K74 S75 R76 M78 R79 R82 G94 G96 L97 S98 P80380 25198768 RNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA 4w2b C 3.60 BS01 NUC A 1 K4 K7 P8 Y9 T10 P11 S12 R13 R14 F15 V18 F21 E28 L33 L37 K38 K39 G41 R43 N44 N45 Q46 G47 R48 I49 T50 V51 R52 R54 G56 H58 K59 R60 L61 Y62 R63 K68 Y84 P86 N87 R88 D99 G100 E101 K102 E148 P149 K150 K151 K154 L155 A156 R157 A158 A159 G160 Y172 L177 P178 S179 E181 R183 H186 A199 H201 K202 L206 G207 K208 A209 G210 R211 S212 R213 W214 L215 R217 R218 P219 H220 V221 R222 G223 A224 A225 M226 N227 P228 V229 D230 H231 H233 G235 G236 E237 G238 R239 A240 P241 R242 G243 R244 P245 P246 A247 S248 P249 W250 G251 W252 Q253 T254 K255 G256 L257 K258 T259 R260 K261 R262 R263 K264 P265 S266 R268 F269 I270 K3 K6 P7 Y8 T9 P10 S11 R12 R13 F14 V17 F20 E27 L32 L36 K37 K38 G40 R42 N43 N44 Q45 G46 R47 I48 T49 V50 R51 R53 G55 H57 K58 R59 L60 Y61 R62 K67 Y83 P85 N86 R87 D98 G99 E100 K101 E147 P148 K149 K150 K153 L154 A155 R156 A157 A158 G159 Y171 L176 P177 S178 E180 R182 H185 A198 H200 K201 L205 G206 K207 A208 G209 R210 S211 R212 W213 L214 R216 R217 P218 H219 V220 R221 G222 A223 A224 M225 N226 P227 V228 D229 H230 H232 G234 G235 E236 G237 R238 A239 P240 R241 G242 R243 P244 P245 A246 S247 P248 W249 G250 W251 Q252 T253 K254 G255 L256 K257 T258 R259 K260 R261 R262 K263 P264 S265 R267 F268 I269 P60405 25198768 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIAR 4w2b C 3.60 BS02 MG C 1 P228 H231 P227 H230 P60405 25198768 AVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIAR 4w2b D 3.60 BS01 NUC A 1 K8 M11 T12 R13 P22 Q35 R37 K41 D42 Y44 Q48 R58 N60 R61 P62 K64 H66 R76 L78 R79 E80 R82 K109 G110 R111 G112 F113 G115 M117 K118 R119 F122 A123 G124 D127 S128 H129 G130 A131 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 P147 G148 R149 V150 Y151 K152 K154 M156 A157 H159 Y160 R164 V165 T166 M168 N169 L170 K185 A187 V188 P189 G190 P191 K202 K203 K8 M11 T12 R13 P22 Q35 R37 K41 D42 Y44 Q48 R58 N60 R61 P62 K64 H66 R76 L78 R79 E80 R82 K109 G110 R111 G112 F113 G115 M117 K118 R119 F122 A123 G124 D127 S128 H129 G130 A131 H132 K133 I134 H135 R136 H137 P138 G139 S140 I141 G142 N143 R144 K145 T146 P147 G148 R149 V150 Y151 K152 K154 M156 A157 H159 Y160 R164 V165 T166 M168 N169 L170 K185 A187 V188 P189 G190 P191 K202 K203 Q5SHN8 25198768 MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLGFLPQNPKRVNRPLKGHFAKAGVEPVRILREIRDFNPEGDTVTVEIFKPGERVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNRKTPGRVYKGKKMAGHYGAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRETKKAA 4w2b E 3.60 BS01 NUC A 1 N29 H31 W34 E35 R38 Q40 L41 K43 R44 R45 R46 T48 A49 S50 T51 K52 T53 R54 G55 V57 A58 Y59 S60 G61 R62 K63 W65 P66 Q67 K68 H69 G71 R72 A73 R74 H75 G76 I78 P81 I82 F83 V84 G85 V88 V89 F90 P92 P94 R95 Y99 T100 L101 P102 K103 K104 V105 R106 K108 K135 T136 R165 R168 N169 L170 P171 V174 T175 E179 G180 N182 Y184 R205 N24 H26 W29 E30 R33 Q35 L36 K38 R39 R40 R41 T43 A44 S45 T46 K47 T48 R49 G50 V52 A53 Y54 S55 G56 R57 K58 W60 P61 Q62 K63 H64 G66 R67 A68 R69 H70 G71 I73 P76 I77 F78 V79 G80 V83 V84 F85 P87 P89 R90 Y94 T95 L96 P97 K98 K99 V100 R101 K103 K130 T131 R160 R163 N164 L165 P166 V169 T170 E174 G175 N177 Y179 R200 Q5SHN9 25198768 VYQIPVLSPSGRRELAADLPAEINPHLLWEVVRWQLAKRRRGTASTKTRGEVAYSGRKIWPQKHTGRARHGDIGAPIFVGGGVVFGPKPRDYSYTLPKKVRKKGLAMAVADRAREGKLLLVEAFAGVNGKTKEFLAWAKEAGLDGSESVLLVTGNELVRRAARNLPWVVTLAPEGLNVYDIVRTERLVMDLDAWEVFQNRIG 4w2b F 3.60 BS01 NUC A 1 K36 V38 N40 G42 L43 G44 E45 T71 R72 A73 K74 K75 I77 N79 F80 L82 I88 R91 S124 D126 R128 N130 N132 L133 G134 L135 R136 G154 M155 D156 A158 V160 K35 V37 N39 G41 L42 G43 E44 T70 R71 A72 K73 K74 I76 N78 F79 L81 I87 R90 S123 D125 R127 N129 N131 L132 G133 L134 R135 G153 M154 D155 A157 V159 Q5SHQ0 25198768 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4w2b F 3.60 BS02 NUC B 1 P2 N27 W29 E30 R33 Q66 K67 A69 V70 R91 V92 T93 R95 R96 P1 N26 W28 E29 R32 Q65 K66 A68 V69 R90 V91 T92 R94 R95 Q5SHQ0 25198768 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4w2b G 3.60 BS01 NUC A 1 S2 R3 I4 R59 K62 S63 G66 L67 N74 G108 F109 S110 H111 K138 Q139 G142 Q143 R152 Y157 H158 K160 R170 S1 R2 I3 R58 K61 S62 G65 L66 N73 G107 F108 S109 H110 K137 Q138 G141 Q142 R151 Y156 H157 K159 R169 Q5SHQ3 25198768 SRIGRLPIPVPKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRL 4w2b H 3.60 BS01 NUC A 1 K22 P23 G24 Y25 N28 Y29 R33 S42 K45 A46 A49 R50 R52 K56 K22 P23 G24 Y25 N28 Y29 R33 S42 K45 A46 A49 R50 R52 K56 Q5SLQ1 25198768 MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEARIRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEALSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVVA 4w2b I 3.60 BS01 NUC A 1 K2 T3 V5 W13 T22 L23 G24 R25 T28 R35 K37 P44 N45 F51 T63 G64 K65 K66 Q69 K70 Y72 R74 Y75 S76 Y78 P79 G80 K83 K89 R97 E100 H101 A102 G105 M106 P108 K109 P111 L112 R114 F117 K118 P129 K2 T3 V5 W13 T22 L23 G24 R25 T28 R35 K37 P44 N45 F51 T63 G64 K65 K66 Q69 K70 Y72 R74 Y75 S76 Y78 P79 G80 K83 K89 R97 E100 H101 A102 G105 M106 P108 K109 P111 L112 R114 F117 K118 P129 P60488 25198768 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKL 4w2b K 3.60 BS01 NUC A 1 L3 S4 R7 P8 N9 G11 A12 N13 K14 R15 R16 K17 R18 G20 R21 G22 P23 G24 S25 G28 K29 T30 A31 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 L45 K46 D47 P48 R49 R50 F51 E52 G53 G54 R55 S56 L59 M60 R61 L62 P63 K64 R65 G66 M67 Q68 G69 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 G104 K107 K108 K113 L115 G116 E117 S131 K132 S133 L3 S4 R7 P8 N9 G11 A12 N13 K14 R15 R16 K17 R18 G20 R21 G22 P23 G24 S25 G28 K29 T30 A31 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 L45 K46 D47 P48 R49 R50 F51 E52 G53 G54 R55 S56 L59 M60 R61 L62 P63 K64 R65 G66 M67 Q68 G69 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 G104 K107 K108 K113 L115 G116 E117 S131 K132 S133 Q5SHQ7 25198768 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA 4w2b L 3.60 BS01 NUC A 1 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 T21 K22 G23 Y26 W41 Q45 Q46 A49 R56 R59 K63 R67 F69 D71 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 T21 K22 G23 Y26 W41 Q45 Q46 A49 R56 R59 K63 R67 F69 D71 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P60489 25198768 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4w2b N 3.60 BS02 NUC B 1 R15 K19 R25 F29 R30 S31 L32 K33 Y36 Q38 I40 G45 V46 T47 S50 S52 L54 A55 K57 N61 K62 T63 K93 H95 G96 R97 R14 K18 R24 F28 R29 S30 L31 K32 Y35 Q37 I39 G44 V45 T46 S49 S51 L53 A54 K56 N60 K61 T62 K92 H94 G95 R96 Q5SHQ4 25198768 ARLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 4w2b P 3.60 BS01 NUC A 1 P2 R3 A4 K5 T6 G7 V8 V9 R10 R11 R12 K13 H14 K15 K16 K19 K22 G23 Y24 W25 G26 L27 R28 S29 K30 S31 F32 R33 K34 R36 E37 F40 A41 A42 Y45 A46 Y47 H49 R50 K51 R52 R53 K54 R55 F57 R58 R59 W61 I62 V63 N66 R70 N75 Y76 S77 I80 H81 R92 K93 N94 Q117 P1 R2 A3 K4 T5 G6 V7 V8 R9 R10 R11 K12 H13 K14 K15 K18 K21 G22 Y23 W24 G25 L26 R27 S28 K29 S30 F31 R32 K33 R35 E36 F39 A40 A41 Y44 A45 Y46 H48 R49 K50 R51 R52 K53 R54 F56 R57 R58 W60 I61 V62 N65 R69 N74 Y75 S76 I79 H80 R91 K92 N93 Q116 P60491 25198768 PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRKRRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVREPQVFAELVERAKAAQG 4w2b T 3.60 BS01 NUC A 1 R2 K4 H6 K8 K9 S17 G18 K19 V30 P32 K34 Y35 I44 V45 K47 A48 V49 V51 G58 G59 F60 H68 S70 K71 R73 R84 V85 R1 K3 H5 K7 K8 S16 G17 K18 V29 P31 K33 Y34 I43 V44 K46 A47 V48 V50 G57 G58 F59 H67 S69 K70 R72 R83 V84 Q5SHP9 25198768 RVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVRVSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCAKCG 4w2b U 3.60 BS01 NUC A 1 I120 I146 G147 S149 H151 E168 E169 T170 P176 I120 I146 G147 S149 H151 E168 E169 T170 P176 Q5SHZ1 25198768 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 4w2b U 3.60 BS02 NUC B 1 R10 P15 R19 V27 Y29 N30 N34 K36 R72 Q73 N75 R79 E84 H85 D87 F89 R10 P15 R19 V27 Y29 N30 N34 K36 R72 Q73 N75 R79 E84 H85 D87 F89 Q5SHZ1 25198768 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 4w2b V 3.60 BS01 NUC A 1 H3 K4 G8 S9 T10 R11 N12 R14 D15 S16 Q17 A18 K19 R20 V23 K24 R25 Y26 E27 R32 A33 G34 N35 I36 R39 R41 G42 T43 R44 G54 R55 D56 F57 T58 F60 L62 F69 R74 L75 R77 H2 K3 G7 S8 T9 R10 N11 R13 D14 S15 Q16 A17 K18 R19 V22 K23 R24 Y25 E26 R31 A32 G33 N34 I35 R38 R40 G41 T42 R43 G53 R54 D55 F56 T57 F59 L61 F68 R73 L74 R76 P60493 25198768 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRP 4w2b W 3.60 BS01 NUC A 1 S2 K3 K10 R11 I13 V14 A15 N16 I18 Q19 R20 R21 A24 K25 R26 G28 V30 G31 K32 K33 T34 T35 K39 R40 R41 Q42 Y43 P44 N45 Q47 R50 R52 R61 A64 S65 H66 K69 R76 K78 E93 L94 L97 L98 S1 K2 K9 R10 I12 V13 A14 N15 I17 Q18 R19 R20 A23 K24 R25 G27 V29 G30 K31 K32 T33 T34 K38 R39 R40 Q41 Y42 P43 N44 Q46 R49 R51 R60 A63 S64 H65 K68 R75 K77 E92 L93 L96 L97 P60494 25198768 SKVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELLKLL 4w2b Y 3.60 BS01 NUC A 1 K10 S11 I13 Y15 P16 K17 K20 A21 K24 A25 R29 R30 L31 P41 A42 G45 N46 K49 K9 S10 I12 Y14 P15 K16 K19 A20 K23 A24 R28 R29 L30 P40 A41 G44 N45 K48 25198768 PRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVAHLVRVEVVE 4w2b a 3.60 BS01 NUC A 1 A2 K3 H4 P5 V6 P7 K8 K9 K10 T11 S12 K13 A14 R15 R16 D17 A18 R19 R20 S21 H22 H23 T29 V31 P32 P42 H43 Y51 A1 K2 H3 P4 V5 P6 K7 K8 K9 T10 S11 K12 A13 R14 R15 D16 A17 R18 R19 S20 H21 H22 T28 V30 P31 P41 H42 Y50 P80339 25198768 AKHPVPKKKTSKARRDARRSHHALTPPTLVPCPECKAMKPPHTVCPECGYYAGRKVLEV 4w2b b 3.60 BS01 NUC A 1 V5 R6 K8 L10 Y21 T23 E24 K25 K27 R28 P31 R37 K38 Y39 C40 K45 H46 V1 R2 K4 L6 Y17 T19 E20 K21 K23 R24 P27 R33 K34 Y35 C36 K41 H42 P35871 25198768 VRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVK 4w2b d 3.60 BS01 NUC A 1 P2 K3 M4 K5 T6 H7 K8 K12 R13 K15 T17 A18 S19 K21 K26 T27 G28 K29 R30 H31 L32 N33 W34 Q35 S37 G38 K39 E40 I41 R42 Q43 R46 K47 F48 V49 K52 L61 L62 Y64 E65 P1 K2 M3 K4 T5 H6 K7 K11 R12 K14 T16 A17 S18 K20 K25 T26 G27 K28 R29 H30 L31 N32 W33 Q34 S36 G37 K38 E39 I40 R41 Q42 R45 K46 F47 V48 K51 L60 L61 Y63 E64 Q5SKU1 25198768 PKMKTHKGAKKRVKITASGKVVAMKTGKRHLNWQKSGKEIRQKGRKFVLAKPEAERIKLLLPYE 4w2c E 3.60 BS01 NUC A 1 R14 T16 A17 R18 M19 Q20 A21 G22 R24 R25 R27 F45 K47 P49 K57 Y61 F84 G85 A86 K92 A94 A95 T98 I101 A102 G103 L119 T120 K121 E122 S125 R126 N127 N130 Y133 R10 T12 A13 R14 M15 Q16 A17 G18 R20 R21 R23 F41 K43 P45 K53 Y57 F80 G81 A82 K88 A90 A91 T94 I97 A98 G99 L115 T116 K117 E118 S121 R122 N123 N126 Y129 Q5SHQ5 25198768 DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKGE 4w2c H 3.60 BS01 NUC A 1 A2 R3 R4 R6 A7 R10 L12 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 I42 R76 R79 A83 R94 R95 S98 R102 R114 R115 A116 R119 W156 A1 R2 R3 R5 A6 R9 L11 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 I41 R75 R78 A82 R93 R94 S97 R101 R113 R114 A115 R118 W155 P17291 25198768 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4w2c H 3.60 BS02 NUC X 1 Q86 D140 R143 M144 A147 Q85 D139 R142 M143 A146 P17291 25198768 ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW 4w2c M 3.60 BS01 NUC A 1 P5 T6 N8 Q9 L10 R12 R15 E16 K17 K20 K21 K23 V24 K28 G29 P31 F32 R33 R34 K46 K47 N49 S50 A51 L52 R53 K54 K57 T61 Y69 P71 G72 E73 G74 R86 R89 V90 K91 D92 P94 G95 R97 V104 R113 K114 K115 S116 R117 S118 K119 Y120 G121 T122 K123 K124 P1 T2 N4 Q5 L6 R8 R11 E12 K13 K16 K17 K19 V20 K24 G25 P27 F28 R29 R30 K42 K43 N45 S46 A47 L48 R49 K50 K53 T57 Y65 P67 G68 E69 G70 R82 R85 V86 K87 D88 P90 G91 R93 V100 R109 K110 K111 S112 R113 S114 K115 Y116 G117 T118 K119 K120 Q5SHN3 25198768 PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEAA 4w2c O 3.60 BS01 NUC A 1 A2 R3 K4 A5 L6 E8 K9 R12 F16 K17 V18 R19 Y21 T22 R23 C27 R29 A30 R31 S32 Y34 R35 R41 I42 C43 R45 E46 K58 S60 W61 A1 R2 K3 A4 L5 E7 K8 R11 F15 K16 V17 R18 Y20 T21 R22 C26 R28 A29 R30 S31 Y33 R34 R40 I41 C42 R44 E45 K57 S59 W60 Q5SHQ1 25198768 ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW 4w2c Q 3.60 BS01 NUC A 1 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 P15 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 Y32 I33 K35 Y38 P41 R42 K43 T44 W59 S61 V62 G63 Q65 T67 T69 R72 R75 F80 R81 Q82 M1 V2 K3 R5 L6 R8 F9 G10 S11 K12 H13 N14 P15 H16 Y17 R18 D23 A24 R25 R26 K27 R28 G30 K31 Y32 I33 K35 Y38 P41 R42 K43 T44 W59 S61 V62 G63 Q65 T67 T69 R72 R75 F80 R81 Q82 Q5SJH3 25198768 MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQEA 4w2c S 3.60 BS01 NUC A 1 K49 I50 L51 P52 R53 R54 A60 K61 Q63 R64 K68 K71 R72 R74 I75 F81 T82 K31 I32 L33 P34 R35 R36 A42 K43 Q45 R46 K50 K53 R54 R56 I57 F63 T64 Q5SLQ0 25198768 KAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKTIKRARILGLLPFTEKLVRK 4w2d F 3.60 BS02 NUC B 1 P2 N27 W29 E30 K67 P68 A69 V70 T71 R91 V92 T93 R95 R96 R98 P1 N26 W28 E29 K66 P67 A68 V69 T70 R90 V91 T92 R94 R95 R97 Q5SHQ0 25198768 PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK 4w2d G 3.60 BS01 NUC A 1 S2 R3 I4 R59 K62 S63 G66 L67 T70 L71 K85 G108 F109 S110 H111 K138 Q139 G142 Q143 Y157 H158 K160 R170 S1 R2 I3 R58 K61 S62 G65 L66 T69 L70 K84 G107 F108 S109 H110 K137 Q138 G141 Q142 Y156 H157 K159 R169 Q5SHQ3 25198768 SRIGRLPIPVPKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVRVERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGRALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAIRKPSAYHEKGIYYAGEPVRL 4w2d I 3.60 BS01 NUC A 1 K2 T3 V5 W13 T22 L23 G24 R25 T28 A31 R35 K37 N45 F51 T63 K65 K66 Q69 K70 R74 Y75 S76 Y78 G80 G81 L82 K83 H94 R97 H101 A102 G105 M106 P108 P111 L112 R114 K118 R119 K2 T3 V5 W13 T22 L23 G24 R25 T28 A31 R35 K37 N45 F51 T63 K65 K66 Q69 K70 R74 Y75 S76 Y78 G80 G81 L82 K83 H94 R97 H101 A102 G105 M106 P108 P111 L112 R114 K118 R119 P60488 25198768 MKTYVPKQVEPRWVLIDAEGKTLGRLATKIATLLRGKHRPDWTPNVAMGDFVVVVNADKIRVTGKKLEQKIYTRYSGYPGGLKKIPLEKMLATHPERVLEHAVKGMLPKGPLGRRLFKRLKVYAGPDHPHQAQRPEKL 4w2d K 3.60 BS01 NUC A 1 L3 S4 R7 P8 N9 G11 A12 N13 K14 R15 K17 R18 V19 G20 R21 P23 G24 S25 G28 K29 T30 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 L45 K46 P48 R49 R50 F51 E52 G53 G54 R55 S56 L59 M60 R61 L62 P63 K64 G66 M67 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 G104 L105 K107 K108 K113 L115 G116 E117 S131 K132 S133 L3 S4 R7 P8 N9 G11 A12 N13 K14 R15 K17 R18 V19 G20 R21 P23 G24 S25 G28 K29 T30 T32 R33 G34 H35 K36 G37 Q38 K39 S40 R41 S42 G43 L45 K46 P48 R49 R50 F51 E52 G53 G54 R55 S56 L59 M60 R61 L62 P63 K64 G66 M67 Q70 V71 P72 G73 E74 I75 K76 R77 Q81 N84 G104 L105 K107 K108 K113 L115 G116 E117 S131 K132 S133 Q5SHQ7 25198768 MKLSDLRPNPGANKRRKRVGRGPGSGHGKTATRGHKGQKSRSGGLKDPRRFEGGRSTTLMRLPKRGMQGQVPGEIKRPRYQGVNLKDLARFEGEVTPELLVRAGLLKKGYRLKILGEGEAKPLKVVAHAFSKSALEKLKAAGGEPVLLEA 4w2d L 3.60 BS01 NUC A 1 P4 R5 R6 K8 Y9 R10 K11 Q12 Q13 R14 G15 R16 L17 K18 T21 K22 G23 G24 Y26 W41 Q46 A49 R56 K63 F65 R67 F69 D71 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P4 R5 R6 K8 Y9 R10 K11 Q12 Q13 R14 G15 R16 L17 K18 T21 K22 G23 G24 Y26 W41 Q46 A49 R56 K63 F65 R67 F69 D71 Y74 K76 K77 L79 E80 V81 R82 M83 G84 K85 G86 R101 R119 I120 H123 K124 P126 K128 Q141 P60489 25198768 MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ 4w2d N 3.60 BS02 NUC B 1 K11 R15 K19 R25 F29 R30 S31 L32 K33 H34 Y36 Q38 I40 G45 V46 T47 S50 L54 A55 N61 K62 T63 Y92 K93 H95 G96 R97 K10 R14 K18 R24 F28 R29 S30 L31 K32 H33 Y35 Q37 I39 G44 V45 T46 S49 L53 A54 N60 K61 T62 Y91 K92 H94 G95 R96 Q5SHQ4 25198768 ARLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF 4w2d U 3.60 BS01 NUC A 1 R112 Q118 I120 I146 G147 D148 T170 A173 V175 P176 K182 R112 Q118 I120 I146 G147 D148 T170 A173 V175 P176 K182 Q5SHZ1 25198768 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 4w2d U 3.60 BS02 NUC B 1 R10 K14 P15 R19 Y29 N30 R31 N34 R72 Q73 N75 R79 E84 H85 D87 F89 R10 K14 P15 R19 Y29 N30 R31 N34 R72 Q73 N75 R79 E84 H85 D87 F89 Q5SHZ1 25198768 MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKL 4w2d V 3.60 BS01 NUC A 1 A2 H3 K4 G8 S9 T10 N12 R14 D15 S16 Q17 A18 K19 R20 K24 R25 Y26 E27 G28 Q29 A33 G34 N35 I36 R39 R41 G42 T43 R44 F45 G54 R55 D56 F57 T58 F60 F69 R74 L75 R77 A1 H2 K3 G7 S8 T9 N11 R13 D14 S15 Q16 A17 K18 R19 K23 R24 Y25 E26 G27 Q28 A32 G33 N34 I35 R38 R40 G41 T42 R43 F44 G53 R54 D55 F56 T57 F59 F68 R73 L74 R76 P60493 25198768 AHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRP 4w2d W 3.60 BS01 NUC A 1 S2 K3 K10 R11 I13 V14 A15 N16 I18 Q19 R20 R21 K25 R26 G28 V30 G31 K32 K33 T34 T35 I37 S38 K39 R40 R41 Q42 Y43 P44 N45 Q47 K48 R50 R52 R61 A64 S65 H66 K69 R76 K78 K88 E93 L97 L98 S1 K2 K9 R10 I12 V13 A14 N15 I17 Q18 R19 R20 K24 R25 G27 V29 G30 K31 K32 T33 T34 I36 S37 K38 R39 R40 Q41 Y42 P43 N44 Q46 K47 R49 R51 R60 A63 S64 H65 K68 R75 K77 K87 E92 L96 L97 P60494 25198768 SKVCEISGKRPIVANSIQRRGKAKREGGVGKKTTGISKRRQYPNLQKVRVRVAGQEITFRVAASHIPKVYELVERAKGLKLEGLSPKEIKKELLKLL 4w2d b 3.60 BS01 NUC A 1 V5 R6 K8 R19 T23 E24 K25 K27 R28 P31 R37 K38 Y39 C40 K45 H46 V1 R2 K4 R15 T19 E20 K21 K23 R24 P27 R33 K34 Y35 C36 K41 H42 P35871 25198768 VRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVK 4w2d e 3.60 BS01 NUC A 1 M1 V3 R4 A5 S6 V7 K8 K15 V16 I17 R18 R19 H20 G21 R22 Y24 P30 K31 K33 R35 Q36 G37 M1 V3 R4 A5 S6 V7 K8 K15 V16 I17 R18 R19 H20 G21 R22 Y24 P30 K31 K33 R35 Q36 G37 Q5SHR2 25198768 MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG 4w9s A 1.80 BS03 3K1 A 1 K34 A37 I38 H41 E80 D108 E119 I120 R124 K134 K39 A42 I43 H46 E85 D113 E124 I125 R129 K139 P13166 25225968 GPLGSMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE 4wd7 A 2.90 BS01 ZN A 1 K188 E191 K167 E170 S7AS11 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQ 4wd7 A 2.90 BS02 ZN A 2 H108 H111 H87 H90 S7AS11 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQ 4wd7 A 2.90 BS03 ZN A 3 D261 D269 D240 D248 S7AS11 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQ 4wd7 B 2.90 BS01 ZN B 1 D190 H194 D169 H173 S7AS11 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQHP 4wd7 B 2.90 BS02 ZN B 2 H108 H111 H290 H87 H90 H269 S7AS11 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQHP 4wd7 D 2.90 BS02 ZN D 2 D133 T135 D112 T114 S7AS11 SKIIFRLLLNVLMSIIAIISYQWYEQLGIHLTVAPFSLLGIAIAIFLGFRNSASYSRFVEARNLWGTVLIAERTLVRQLRNILPAEHDAHRRIVSYLVAFSWSLKHQLRKTDPTADLRRLLPEERVTEILASSMPTNRILLLAGNEIGQLREAGKLSDITYGLMDNKLDELAHVLGGCERLATTPVPFAYTLILQRTVYLFCTLLPFALVGDLHYMTPFVSVFISYTFLSWDSLAEELEDPFGTAANDLPLNAMCNTIERNLLDMTGQ 4wgh A 1.80 BS01 NAP A 1 G20 T21 W22 D50 Y55 K80 S142 N143 Q165 Y193 C194 P195 L196 Q198 A199 R201 A224 I240 P241 K242 A243 A244 S245 H248 Q251 N252 G19 T20 W21 D49 Y54 K79 S141 N142 Q164 Y192 C193 P194 L195 Q197 A198 R200 A223 I239 P240 K241 A242 A243 S244 H247 Q250 N251 V3S9R5 VKKTVRFGEQAAVPAIGLGTWYMGEHAAQRQQEVAALRAGIDHGLTVIDTAEMYADGGAEEVVGQAIRGLRDRVVLVSKVYPWHAGKAAMHRACENSLRRLQTDYLDMYLLHWRGDIPLQETVEAMEKLVAEGKIRRWGVSNLDTEDMQALWRTADGEHCATNQVLYHLASRGIEYDLLPWCQQHSLPVMAYCPLAQAGRLRDGLFQHSDIINMANARGITVAQLLLAWVIRHPGVLAIPKAASIEHVVQNAAALDIVLSGEELAQLDRLYPPPQRKNRLDMV 4wgh A 1.80 BS02 ACT A 1 W22 M54 Y55 H113 W21 M53 Y54 H112 V3S9R5 VKKTVRFGEQAAVPAIGLGTWYMGEHAAQRQQEVAALRAGIDHGLTVIDTAEMYADGGAEEVVGQAIRGLRDRVVLVSKVYPWHAGKAAMHRACENSLRRLQTDYLDMYLLHWRGDIPLQETVEAMEKLVAEGKIRRWGVSNLDTEDMQALWRTADGEHCATNQVLYHLASRGIEYDLLPWCQQHSLPVMAYCPLAQAGRLRDGLFQHSDIINMANARGITVAQLLLAWVIRHPGVLAIPKAASIEHVVQNAAALDIVLSGEELAQLDRLYPPPQRKNRLDMV