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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
YTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYE
LEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITMSKSLEE
LQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRLKCYLH
ETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALV

The query sequence (length=281) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2v8q:E 304 295 1.0000 0.9243 0.9525 0.0 6b1u:E, 6b1u:F, 6b2e:C, 8bik:C, 8bik:F, 6c9f:C, 6c9g:C, 6c9h:C, 6c9j:C, 4cfe:E, 4cfe:F, 4cff:E, 4cff:F, 4cfh:E, 6e4t:C, 6e4u:C, 6e4w:C, 4eag:C, 4eai:C, 4eaj:C, 4eak:C, 4eal:C, 5ezv:E, 5ezv:F, 5iso:E, 5iso:F, 7jhg:G, 7jhh:G, 7jij:G, 5kq5:C, 7m74:G, 7myj:E, 7myj:F, 4qfg:C, 4qfr:C, 4rer:G, 4rew:G, 5t5t:C, 5ufu:C, 2uv4:A, 2uv5:A, 2uv6:A, 2uv7:A, 2v92:E, 2v9j:E, 2y8l:E, 2y8q:E, 2ya3:E, 4zhx:E, 4zhx:F
2 4qfs:C 267 281 0.9502 1.0000 0.9502 0.0
3 2oox:E 333 297 0.3594 0.3033 0.3401 1.81e-53 2oox:G, 2ooy:G, 2ooy:E, 2qr1:G, 2qr1:E, 2qrc:G, 2qrc:E, 2qrd:G, 2qrd:E, 2qre:G, 2qre:E
4 3tdh:C 316 295 0.3737 0.3323 0.3559 4.39e-50 3t4n:C, 3te5:C
5 3lfz:A 280 286 0.2135 0.2143 0.2098 1.05e-06 3kh5:A
6 3lfz:A 280 199 0.1459 0.1464 0.2060 8.44e-05 3kh5:A
7 3kpc:A 124 121 0.1352 0.3065 0.3140 4.36e-06 3kpb:A, 3kpb:C, 3kpb:D, 3kpd:A, 3kpd:B, 3kpd:C, 3kpd:D
8 3kpc:A 124 126 0.1103 0.2500 0.2460 0.002 3kpb:A, 3kpb:C, 3kpb:D, 3kpd:A, 3kpd:B, 3kpd:C, 3kpd:D
9 8qqp:A 464 149 0.1246 0.0754 0.2349 7.37e-06 8q65:A, 8q65:E, 8qqp:B, 8qqp:C, 8qqp:D, 8qqp:E, 8qqp:F, 8qqp:G, 8qqp:H, 8qqq:A, 8qqq:B, 8qqq:C, 8qqq:D, 8qqq:E, 8qqq:F, 8qqq:G, 8qqq:H, 8qqr:A, 8qqr:B, 8qqr:C, 8qqr:D, 8qqr:E, 8qqr:F, 8qqr:G, 8qqr:H, 8qqt:A, 8qqt:B, 8qqt:C, 8qqt:D, 8qqt:E, 8qqt:F, 8qqt:G, 8qqt:H
10 8qqp:A 464 91 0.0890 0.0539 0.2747 0.34 8q65:A, 8q65:E, 8qqp:B, 8qqp:C, 8qqp:D, 8qqp:E, 8qqp:F, 8qqp:G, 8qqp:H, 8qqq:A, 8qqq:B, 8qqq:C, 8qqq:D, 8qqq:E, 8qqq:F, 8qqq:G, 8qqq:H, 8qqr:A, 8qqr:B, 8qqr:C, 8qqr:D, 8qqr:E, 8qqr:F, 8qqr:G, 8qqr:H, 8qqt:A, 8qqt:B, 8qqt:C, 8qqt:D, 8qqt:E, 8qqt:F, 8qqt:G, 8qqt:H
11 4gqy:A 147 129 0.1174 0.2245 0.2558 4.34e-05 4gqy:B, 4gqy:C, 4gqy:D
12 4gqy:A 147 130 0.1103 0.2109 0.2385 0.010 4gqy:B, 4gqy:C, 4gqy:D
13 3fhm:A 136 102 0.0925 0.1912 0.2549 9.80e-05 3fhm:D, 3fhm:B, 3fhm:C
14 2rc3:C 128 124 0.1103 0.2422 0.2500 0.046 2rc3:A, 2rc3:D, 2rc3:B
15 7cfk:B 166 103 0.0961 0.1627 0.2621 0.20 7cfi:A, 7cfk:A
16 7oj1:B 425 108 0.0783 0.0518 0.2037 0.30
17 5g5x:A 119 53 0.0534 0.1261 0.2830 0.36
18 5g5x:A 119 90 0.0961 0.2269 0.3000 5.1
19 4fry:B 138 118 0.0961 0.1957 0.2288 0.50 4fry:A
20 2yvx:A 442 55 0.0712 0.0452 0.3636 0.60 8h5e:A, 4u9n:B, 4wib:B, 5x9g:A, 5x9g:B, 5x9g:C, 5x9g:D, 5x9h:A, 5x9h:B, 2yvx:B, 2yvx:C, 2yvx:D, 2yvy:A, 2zy9:A, 2zy9:B
21 2qh1:B 185 115 0.0996 0.1514 0.2435 1.4 1pvm:A, 1pvm:B, 2qh1:A
22 4air:A 304 64 0.0712 0.0658 0.3125 1.5 4air:B
23 3ddj:A 279 116 0.1032 0.1039 0.2500 1.6
24 3ddj:A 279 180 0.1352 0.1362 0.2111 5.4
25 3t4p:A 319 64 0.0712 0.0627 0.3125 1.7 3tbh:A
26 7qem:B 428 148 0.1317 0.0864 0.2500 1.9 7qdx:A, 7qdx:B, 7qem:A, 7qem:D
27 3jtf:B 125 26 0.0356 0.0800 0.3846 2.0 3jtf:A
28 7pji:A 445 94 0.0925 0.0584 0.2766 2.2 4dqw:A, 4dqw:B, 6gk9:A, 6gk9:D, 7pji:B
29 3pc3:A 504 46 0.0356 0.0198 0.2174 3.2 3pc2:A, 3pc4:A
30 6mo0:A 164 38 0.0427 0.0732 0.3158 3.5 6mo0:B, 6mo1:A, 6mo1:B, 6mo2:A, 6mo2:B
31 8b9y:C 330 66 0.0676 0.0576 0.2879 3.6 8b9y:A, 8b9y:B, 8b9y:D
32 4lma:A 318 66 0.0641 0.0566 0.2727 4.0 4lma:B
33 6skf:BK 142 42 0.0463 0.0915 0.3095 4.1 6skg:BK, 6th6:BK, 4v4n:AI, 4v6u:BI
34 6ao8:A 569 42 0.0498 0.0246 0.3333 4.2
35 7jrg:A 487 82 0.0783 0.0452 0.2683 4.4 8e73:A, 8e73:M, 7jrg:M, 7jrp:A, 7jrp:M
36 5ks7:A 123 37 0.0498 0.1138 0.3784 4.9 5ks7:B
37 8gpv:A 255 211 0.1566 0.1725 0.2085 5.9
38 7dn3:A 1293 43 0.0463 0.0101 0.3023 7.4 7du2:A
39 7d58:A 1387 43 0.0463 0.0094 0.3023 7.4 7a6h:A, 7ae1:A, 7ae3:A, 7aea:A, 7fji:A, 7fjj:A, 8ity:A, 8iue:A, 8iuh:A
40 7urg:A 401 43 0.0427 0.0299 0.2791 8.3 7urg:B
41 1zfj:A 476 154 0.1103 0.0651 0.2013 8.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218