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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
YEPKSVKEIFIEMKDTVELMVDLAYASLLFGDKEIAEEVLELEERIDLLNYQLMMHSVLAARNVKEAEQVITILQIANAI
EDISNAAGDLAKMVLEGVELHPVIKETILEGEEIIGKIQVYPESVIVGKTLGELDLATNTGVWIIAVRRGKRWIFGPNEN
FKIRAGDVLIGRGTRTSIDHLKEIARGAIR

The query sequence (length=190) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2bko:A 190 190 1.0000 1.0000 1.0000 8.39e-136
2 4xtt:A 85 58 0.1000 0.2235 0.3276 4.96e-07 4xtt:B
3 6oly:C 318 149 0.2158 0.1289 0.2752 1.43e-05 2aef:A, 2aef:B, 5bkj:A, 5bkj:C, 5bkj:E, 5bkj:G, 5bkk:A, 5bkk:C, 5bkk:G, 8fz7:A, 8fz7:C, 8fz7:E, 8fz7:G, 3kxd:A, 3kxd:B, 4l73:A, 4l73:B, 4l74:A, 4l74:B, 4l75:A, 4l75:B, 4l75:C, 4l75:D, 4l75:E, 4l75:F, 4l76:A, 4l76:B, 4l76:C, 4l76:D, 4l76:E, 4l76:F, 1lnq:A, 1lnq:B, 1lnq:C, 1lnq:D, 1lnq:E, 1lnq:F, 1lnq:G, 1lnq:H, 6oly:A, 6oly:B, 6oly:D, 3rbx:A, 3rbx:B, 3rbx:C, 3rbx:D, 3rbx:E, 3rbx:F, 6u5n:A, 6u5n:E, 6u5n:B, 6u5n:F, 6u5n:C, 6u5n:G, 6u5n:D, 6u5n:H, 6u5p:A, 6u5p:E, 6u5p:B, 6u5p:F, 6u5p:C, 6u5p:G, 6u5p:D, 6u5p:H, 6u5r:A, 6u5r:B, 6u5r:C, 6u5r:D, 6u5r:E, 6u5r:F, 6u5r:G, 6u5r:H, 6uwn:A, 6uwn:E, 6uwn:B, 6uwn:F, 6uwn:C, 6uwn:G, 6uwn:D, 6uwn:H, 6ux4:A, 6ux4:E, 6ux4:B, 6ux4:F, 6ux4:C, 6ux4:G, 6ux4:D, 6ux4:H
4 3rbz:A 289 149 0.2158 0.1419 0.2752 1.50e-05 3rbz:B, 3rbz:C, 3rbz:D
5 6i8v:A 216 90 0.1474 0.1296 0.3111 6.56e-04
6 7b5y:A 206 156 0.2105 0.1942 0.2564 0.023 7b5u:A, 7b5u:B, 7b5y:C, 7b5y:B, 7b5y:D, 7oz3:A, 7oz3:B, 7oz3:C, 7oz3:D
7 7agv:F 163 59 0.1053 0.1227 0.3390 0.029 7agv:A, 7agv:B, 7agv:C, 7agv:D, 7agv:E, 7agv:G, 7agv:H, 7ahm:A, 7ahm:B, 7ahm:C, 7ahm:D
8 6aqz:A 334 18 0.0526 0.0299 0.5556 2.4 6aqz:B, 6aqz:C, 6aqz:E, 6aqz:F
9 5y4c:A 249 63 0.1000 0.0763 0.3016 3.8
10 4v12:A 337 24 0.0684 0.0386 0.5417 5.0
11 1fvp:A 231 69 0.1421 0.1169 0.3913 5.8 1fvp:B
12 4e5y:C 290 18 0.0526 0.0345 0.5556 6.1
13 8him:B 971 31 0.0632 0.0124 0.3871 6.8
14 4bkp:C 326 18 0.0526 0.0307 0.5556 6.9 4b8w:A, 4b8w:B, 4b8z:A, 4b8z:B, 4b8z:C, 4b8z:D, 4bkp:A, 4bkp:B, 4bkp:D, 4bl5:A, 4bl5:B, 4bl5:C, 4bl5:D, 4bl5:E, 4bl5:F, 4bl5:G, 4bl5:H, 4bl5:I, 4bl5:J, 4bl5:K, 4bl5:L, 4e5y:A, 4e5y:B, 4e5y:D
15 6njo:D 413 21 0.0526 0.0242 0.4762 7.4 6njo:B, 6njo:A, 6njo:C, 6njo:E, 6njp:B, 6njp:C, 6njp:D, 6njp:E, 2obl:A, 2obm:A
16 8iuf:B9 151 35 0.0684 0.0861 0.3714 9.0 8j9h:B9, 8j9i:B9, 8j9j:B9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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