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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVIVSVLKGSFVFTADMVRILGDFGVPTRVEFLRCDIRGK
HVLVLEDILDTALTLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVIL
KPSVYETWGK

The query sequence (length=170) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6aps:A 185 171 1.0000 0.9189 0.9942 1.72e-121 6aps:B, 6apt:A, 6apt:B, 6apu:A, 6apu:B, 6apv:A, 6apv:B, 6apv:C, 6apv:D, 5jsq:A, 5jsq:B, 5jv5:A, 5jv5:B, 5k51:A, 5k51:B, 5k51:C, 5k51:D, 5kam:A, 5kam:C, 5kap:A, 5kap:B, 6mxg:A, 6mxg:B, 7sb7:A, 7sb7:B, 8tr1:A, 8tr1:B, 8tr1:C, 8tr1:D, 8ts4:A, 8ts4:B
2 1p17:B 204 180 0.5647 0.4706 0.5333 1.35e-65 1i0i:A, 1i0i:B, 1i0l:A, 1i0l:B, 1i13:A, 1i13:B, 1i14:A, 1i14:B, 1p17:A, 1p17:C, 1p17:D, 1p18:A, 1p18:B, 1p19:A, 1p19:B, 1p19:C, 1p19:D, 1tc1:A, 1tc1:B, 1tc2:A, 1tc2:B
3 6mxc:C 220 197 0.4706 0.3636 0.4061 7.99e-45 6aqo:A, 6aqo:B, 6aqo:C, 6aqo:D, 6aqo:E, 6aqo:F, 6ar9:A, 6ar9:B, 6ar9:C, 6ar9:D, 6ar9:E, 6ar9:F, 6mxb:A, 6mxb:B, 6mxb:C, 6mxb:D, 6mxb:E, 6mxb:F, 6mxc:A, 6mxc:B, 6mxc:D, 6mxc:E, 6mxc:F, 6mxd:A, 6mxd:B, 6mxd:C, 6mxd:D, 7scr:A, 7scr:C, 7scr:B, 7scr:D, 7scr:E, 7scr:F
4 7cmj:A 184 182 0.4176 0.3859 0.3901 1.08e-43 1pzm:A, 1pzm:B
5 8fx3:B 223 196 0.4412 0.3363 0.3827 1.47e-41 8fwy:A, 8fwy:B, 8fwz:A, 8fwz:B, 8fx0:A, 8fx0:B, 8fx1:A, 8fx1:B, 8fx2:A, 8fx2:B, 8fx3:A
6 3kb8:A 201 177 0.3824 0.3234 0.3672 1.17e-27 6d9r:A, 6d9r:B, 6d9s:A, 6d9s:B, 3h83:A, 3h83:B, 3kb8:B
7 5kny:B 187 182 0.3412 0.3102 0.3187 5.40e-26 5knp:A, 5knp:B, 5knp:C, 5knp:D, 5knq:A, 5knq:B, 5knq:C, 5knq:D, 5kny:A, 5kny:C, 5kny:D, 4rht:A, 4rht:B, 4rht:C, 4rht:D, 4rhu:A, 4rhu:B, 4rhu:C, 4rhu:D, 4rhu:E, 4rhu:F, 4rhx:A, 4rhx:B, 4rhx:C, 4rhx:D, 4rhy:A, 4rhy:B, 4rhy:C, 4rhy:D
8 4qyi:B 171 165 0.3294 0.3275 0.3394 4.99e-25 4qyi:A, 4qyi:C, 4qyi:D, 4qyi:E
9 4pfq:C 184 178 0.3294 0.3043 0.3146 1.86e-24 4pfq:A, 4pfq:B, 4pfq:D, 4pfq:E, 4pfq:F, 4pfq:G, 4pfq:H
10 5knx:B 176 169 0.3235 0.3125 0.3254 6.94e-24 1g9s:A, 1g9s:B, 1g9t:A, 1g9t:B, 1grv:B, 1grv:A, 1j7j:A, 1j7j:B, 5knr:A, 5knr:B, 5kns:A, 5kns:B, 5knt:A, 5knt:B, 5knu:A, 5knu:B, 5knv:A, 5knv:B, 5knx:A
11 2geb:A 184 181 0.3235 0.2989 0.3039 5.06e-23 1r3u:A, 1r3u:B, 1yfz:A, 1yfz:B
12 6igs:B 167 171 0.2941 0.2994 0.2924 1.39e-20 6igs:A, 6igs:C, 6igs:D
13 1hgx:A 164 167 0.3176 0.3293 0.3234 1.80e-20
14 5ipf:A 201 166 0.3000 0.2537 0.3072 2.15e-18 5ipf:B, 5ipf:C, 5ipf:D
15 3acc:A 166 166 0.3000 0.3072 0.3072 3.23e-18 3acd:A
16 5brn:B 194 132 0.2353 0.2062 0.3030 2.71e-16 5bsk:A, 5bsk:B, 5bsk:C, 5bsk:D, 4kn6:A, 8tpy:A, 8tpy:B, 8tpy:C, 8tpy:D
17 2jbh:B 213 155 0.2412 0.1925 0.2645 3.69e-14 2jbh:A
18 1bzy:A 214 150 0.2353 0.1869 0.2667 3.94e-14 6bnj:A, 6bnj:B, 6bnj:C, 6bnj:D, 5brn:A, 5brn:C, 5brn:D, 1bzy:B, 1bzy:C, 1bzy:D, 1d6n:A, 1d6n:B, 3gep:A, 3gep:B, 3ggc:A, 3ggc:B, 3ggj:A, 3ggj:B, 5hia:A, 5hia:B, 5hia:C, 5hia:D, 1hmp:A, 1hmp:B, 4ijq:A, 4ijq:B, 4ijq:C, 4ijq:D, 4rab:A, 4rab:B, 4rab:C, 4rab:D, 4rac:A, 4rac:B, 4rac:C, 4rac:D, 4rad:A, 4rad:B, 4rad:C, 4rad:D, 4rad:E, 4rad:F, 4rad:G, 4rad:H, 4ran:A, 4ran:B, 4ran:C, 4ran:D, 4rao:A, 4rao:B, 4rao:C, 4rao:D, 4raq:A, 4raq:B, 4raq:C, 4raq:D, 7san:A, 7san:B, 7san:C, 7san:D, 8tpv:A, 8tpv:B, 8tpv:C, 8tpv:D, 5w8v:A, 5w8v:B, 5w8v:C, 5w8v:D
19 2vfa:B 205 170 0.2706 0.2244 0.2706 1.28e-13 2vfa:A
20 6bo7:A 220 178 0.2824 0.2182 0.2697 1.88e-12 6bo7:B, 6bo7:C, 6bo7:D, 6bo7:E, 6bo7:F, 6bo7:G, 6bo7:H, 6bo7:I, 6bo7:J, 6bo7:K, 6bo7:L
21 3ozf:B 234 94 0.2294 0.1667 0.4149 5.26e-11 1cjb:A, 1cjb:B, 1cjb:C, 1cjb:D, 3ozf:A, 3ozf:C, 3ozf:D, 3ozg:A, 3ozg:B, 3ozg:C, 3ozg:D, 7tux:A, 7tux:B, 7tux:C, 7tux:D
22 1fsg:A 233 94 0.1647 0.1202 0.2979 9.27e-10 1dbr:A, 1dbr:B, 1dbr:D, 1fsg:C, 1qk3:A, 1qk3:B, 1qk3:C, 1qk3:D, 1qk4:A, 1qk4:B, 1qk4:C, 1qk4:D, 1qk5:A, 1qk5:B
23 5esw:A 190 183 0.2647 0.2368 0.2459 4.37e-09 5esx:A, 5esx:B
24 4p86:A 177 62 0.1235 0.1186 0.3387 0.001 4p86:B, 4p86:C, 4p86:D
25 4zfn:B 177 49 0.1059 0.1017 0.3673 0.004 5bqp:A, 5bqp:B, 5bqp:C, 5bqp:D, 4z1o:A, 4z1o:B, 4zfn:A
26 2igb:B 173 59 0.1118 0.1098 0.3220 0.007 2igb:A, 4p83:A, 4p83:B, 4p83:C, 4p83:D, 1xz8:A, 1xz8:B, 1xzn:A, 1xzn:B
27 5iao:A 171 57 0.1000 0.0994 0.2982 0.012 5iao:C, 5iao:F
28 4trb:B 209 146 0.2176 0.1770 0.2534 0.28 4trc:A, 4trc:B, 4ts5:A, 4ts5:B, 4ts7:A, 4ts7:B
29 3db6:A 287 64 0.1294 0.0767 0.3438 0.38 3d5w:A, 3d5x:A, 3dbe:A
30 3db8:A 261 69 0.1294 0.0843 0.3188 1.5 3dbc:A, 3dbd:A, 3dbf:A
31 5yw5:A 178 132 0.1706 0.1629 0.2197 2.5 5yw5:B, 5yw5:C, 5yw5:D
32 8gy3:C 732 39 0.0706 0.0164 0.3077 5.9
33 5zeb:e 198 25 0.0706 0.0606 0.4800 7.2 6dzi:m, 6dzk:E, 8fr8:f, 7kgb:e, 7msc:e, 7msh:e, 7msm:e, 7msz:e, 7mt2:e, 7mt3:e, 7mt7:e, 5o5j:E, 5o61:BE, 7sfr:e, 5v93:e, 8v9j:e, 8v9k:e, 8v9l:e, 8whx:f, 8wi7:f, 8wi9:f, 8wib:f, 8wid:f, 8wif:f, 5xyu:E, 5zep:e, 5zeu:e
34 8gvh:A 788 95 0.1588 0.0343 0.2842 7.6 8gv8:A, 8gv8:B, 8gvh:B, 8jni:B, 8jni:A, 8zle:A, 8zle:B
35 6nfe:B 299 36 0.0706 0.0401 0.3333 8.1 6nfe:A
36 8cs9:g 832 63 0.1176 0.0240 0.3175 8.6 8cs9:V, 8cs9:e, 8cs9:Y, 8cs9:f, 8cs9:Z, 8cte:P, 8cte:T, 7v0k:O, 7v0k:P
37 1i5e:A 208 57 0.1000 0.0817 0.2982 8.8 1i5e:B
38 8crx:E 179 40 0.0941 0.0894 0.4000 9.4 8cvo:E, 8cwo:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218