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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VVLDKYGYPILYYSKYEDVVIEWNPSVTPVQIEKNYEVKFDVRQVKLRPPKVEAYASLFKSRLSKLKRILRENPEISNVV
DIGKLNYVSGDEEVTIIGLVNSKRETNRGLIFEVEDKTGIVKVFLPKDSEDYREAFKVLPDAVVAFKGFYSKKGIFFANK
FYLPDVPLYRKQKPPLEEKVYAILISDIHVGSREFCEKAFLKFLEWLNGHVESKEEEEIVSRVKYLIIAGDVVDGIGIYP
GQYSDLVIPDIFDQYEALANLLANVPEHITMFIGPGNADAARPAIPQPEFYKEYAKPIYKLKNAIIISNPAVIRLHGRDF
LIAHGRGIEDVVSFVPGKPGLPMVELLKMRHLAPTFGGKVPIAPDPEDLLVIEEVPDLVQMGHVHVYDAVVYRGVQLVNS
ATWQAQTEFQKMVNIVPTPAKVPVVDVESARVVKVLDFSGWC

The query sequence (length=442) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ppt:A 447 446 0.9729 0.9620 0.9641 0.0 6hmf:A, 6hmf:B, 5ihe:A, 5ihe:B, 8ppu:A, 8ppv:A, 6t8h:A
2 6knb:A 450 449 0.6584 0.6467 0.6481 0.0 6knc:A
3 6sjc:B 581 68 0.0566 0.0430 0.3676 0.024 7ap4:A, 7ap4:B, 1efw:A, 1efw:B, 1g51:A, 1g51:B, 6hhv:A, 6hhv:B, 6hhw:A, 6hhw:B, 6hhx:A, 6hhx:B, 6sjc:A
4 4wj3:M 589 68 0.0475 0.0357 0.3088 0.025 4wj3:N, 4wj3:O, 4wj3:P, 4wj4:A
5 1c0a:A 585 50 0.0362 0.0274 0.3200 0.077 1il2:A, 1il2:B
6 1ahp:A 796 96 0.0588 0.0327 0.2708 0.13 1ahp:B, 2asv:A, 2asv:B, 2av6:A, 2av6:B, 2aw3:A, 2aw3:B, 2azd:A, 2azd:B, 1e4o:A, 1e4o:B, 2ecp:A, 2ecp:B, 1l5v:A, 1l5v:B, 1l5w:A, 1l5w:B, 1l6i:A, 1l6i:B, 1qm5:A, 1qm5:B, 8rvk:A
7 7tm7:A 802 101 0.0611 0.0337 0.2673 0.77 7tm7:B
8 5w25:A 583 68 0.0385 0.0292 0.2500 2.5 5w25:B
9 6wbd:B 485 57 0.0362 0.0330 0.2807 5.3 6wbd:A
10 6i52:B 132 83 0.0588 0.1970 0.3133 6.1
11 6v7w:E 234 74 0.0475 0.0897 0.2838 8.8 6d6a:A, 6d6a:B, 6d6a:C, 6d6a:D, 6d6a:E, 6d6a:F, 6d6a:G, 6d6a:H, 6d6b:A, 6d6b:B, 6d6b:C, 6d6b:D, 6d6b:E, 6d6b:F, 6d6b:G, 6d6b:H, 6d6c:A, 6d6c:B, 6d6c:C, 6d6c:D, 6d6c:E, 6d6c:F, 6d6c:G, 6d6c:H, 6d6c:I, 6d6c:J, 6d6c:K, 6d6c:L, 6d6d:A, 6d6d:B, 6d6l:A, 6d6l:B, 6d6l:C, 6d6l:D, 6d6m:A, 6d6m:B, 6d6m:C, 6d6m:D, 6d6n:A, 6d6n:B, 6d6n:C, 6d6n:D, 6d6o:A, 6d6o:B, 6d6o:C, 6d6o:D, 6d6p:A, 6d6p:B, 6d6p:C, 6d6p:D, 3ix3:A, 3ix3:B, 3ix4:A, 3ix4:B, 3ix4:C, 3ix4:D, 3ix4:E, 3ix4:F, 3ix4:G, 3ix4:H, 3ix8:A, 3ix8:B, 3ix8:C, 3ix8:D, 3jpu:A, 3jpu:B, 3jpu:C, 3jpu:D, 3jpu:E, 6mvm:A, 6mvm:B, 6mvn:A, 6mvn:B, 6mwh:A, 6mwh:B, 6mwl:A, 6mwl:B, 6mww:A, 6mww:B, 6mwz:A, 6mwz:B, 4ng2:A, 4ng2:B, 4ng2:C, 4ng2:D, 2uv0:E, 2uv0:F, 2uv0:G, 2uv0:H, 6v7w:B, 6v7x:B
12 3ey9:A 571 45 0.0430 0.0333 0.4222 9.0 3ey9:B, 3eya:A, 3eya:B, 3eya:C, 3eya:D, 3eya:E, 3eya:F, 3eya:G, 3eya:H, 3eya:I, 3eya:J, 3eya:K, 3eya:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218