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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VNIPDKRNTHCKKCNKHTEHKVSQYKKSKEGRNGQGTRRYRRKQRGYHGQTKPILRRKAKVTKKLVIKLRCSVCDAKHQQ
TMKRTKHVEFG

The query sequence (length=91) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6zu5:LOO 91 91 1.0000 1.0000 1.0000 2.52e-62
2 7qep:P2 97 91 0.6703 0.6289 0.6703 4.12e-37
3 4v6w:Co 104 91 0.5714 0.5000 0.5714 1.36e-31 6xu6:Co, 6xu7:Co, 6xu8:Co
4 8p5d:LOO 100 91 0.5714 0.5200 0.5714 1.59e-30 8p60:LOO, 8p60:KOO, 7qca:LOO
5 9bh5:Co 102 92 0.5824 0.5196 0.5761 3.82e-30 9cai:Co
6 4d5y:o 106 93 0.5824 0.5000 0.5699 1.89e-29 7a01:F2, 8a3d:i, 5aj0:Ao, 8b5l:o, 8b6c:o, 9bdl:AL42, 9bdn:AL42, 9bdp:AL42, 7bhp:Lo, 8bhf:b1, 8bpo:n2, 8btk:Bo, 7cpu:Lo, 7cpv:Lo, 4d67:o, 6d90:o, 6d9j:o, 9f1b:Bo, 9f1c:Bo, 9f1d:Bo, 7f5s:Lo, 8fl6:LV, 8fl7:LV, 8fl9:LV, 8fla:LV, 8flb:LV, 8flc:LV, 8fld:LV, 8fle:LV, 8flf:LV, 6frk:o, 6ftg:o, 6fti:o, 6ftj:o, 8g5y:Lo, 8g5z:Lo, 8g60:Lo, 8g61:Lo, 8g6j:Lo, 8glp:Lo, 6gz3:Ao, 6gz4:Ao, 6gz5:Ao, 6hcf:o3, 6hcj:o3, 6hcm:o3, 6hcq:o3, 8idt:W, 8idy:W, 8ifd:2i, 8ife:2i, 8ine:W, 8inf:W, 6ip5:2i, 6ip6:2i, 6ip8:2i, 3j7o:o, 3j7p:o, 3j7q:o, 3j7r:o, 3j92:o, 3jag:o, 3jah:o, 3jai:o, 3jaj:o, 3jan:o, 8jdj:t, 8jdk:t, 8jdl:t, 8jdm:t, 8k2c:Lo, 5lks:Lo, 6lqm:W, 6lsr:W, 6lss:W, 7ls1:i2, 7ls2:i2, 6lu8:W, 5lzs:o, 5lzt:o, 5lzu:o, 5lzv:o, 5lzw:o, 5lzx:o, 5lzy:o, 5lzz:o, 7mdz:o, 6mtb:o, 6mtc:o, 6mtd:o, 6mte:o, 7nfx:o, 7nwg:o3, 7nwh:o, 7nwi:o, 7o7y:Bo, 7o7z:Bo, 7o80:Bo, 7o81:Bo, 7obr:o, 8ohd:Lo, 8oj0:Lo, 8oj5:Lo, 8oj8:Lo, 6ole:p, 6olf:p, 6olg:Ao, 6oli:p, 6olz:Ao, 6om0:p, 6om7:p, 7ow7:i, 7oya:o1, 7oyb:o1, 7oyc:o1, 7oyd:o, 8p2k:Bo, 6p5i:Ao, 6p5j:Ao, 6p5k:Ao, 6p5n:Ao, 8q7z:Bo, 8q87:Bo, 8qfd:o, 7qgg:p, 8qoi:Lo, 7qvp:Lo, 7qvp:Mo, 7qwq:o, 7qwr:o, 7qws:o, 6qzp:Lo, 6r5q:o, 6r6g:o, 6r6p:o, 6r7q:o, 8rjb:o, 8rjc:o, 8rjd:o, 8scb:o, 6sgc:o2, 6swa:m, 5t2c:i, 6t59:o3, 7tm3:o, 7toq:AL42, 7tor:AL42, 7tut:o, 7ucj:o, 7uck:o, 4ug0:Lo, 4ujc:Bo, 4ujd:Ao, 4uje:Co, 4v5z:B4, 4v6x:Co, 6w6l:p, 6xa1:Lo, 7xnx:Lo, 7xny:Lo, 8xsx:Lo, 8xsy:Lo, 8xsz:Lo, 6y0g:Lo, 8y0w:Lo, 8y0x:Lo, 6y2l:Lo, 6y57:Lo, 6y6x:Lo, 8yoo:Lo, 8yop:Lo, 6z6l:Lo, 6z6m:Lo, 6z6n:Lo, 7zjw:Lq, 7zjx:Lq, 6zm7:Lo, 6zme:Lo, 6zmi:Lo, 6zmo:Lo, 6zvk:F2
7 5xxb:n 97 93 0.5934 0.5567 0.5806 1.91e-29
8 4v3p:Lr 105 93 0.5604 0.4857 0.5484 1.35e-28 8azw:Z, 8b2l:Z3, 8ip8:WA, 8ipa:WA, 8ipb:WA, 8jiv:Co, 7qiw:p, 7qiz:p, 4v7e:Co
9 6rm3:LOO 98 91 0.5714 0.5306 0.5714 6.59e-28
10 7pwg:o 94 90 0.5495 0.5319 0.5556 3.85e-26 8br8:Lp, 8brm:Lp, 8bsi:Lp, 8bsj:Lp, 8btd:Lp, 8btr:Lp, 8fru:o, 7pwo:o2
11 4v8m:Bt 105 92 0.5385 0.4667 0.5326 1.38e-25 8a3w:p, 8a98:p, 6az3:p, 3jcs:n, 8ova:Bt, 8ove:Bt, 8ovj:p, 8rxh:Lp, 8rxx:Lp, 5t2a:r, 5t5h:t
12 4v8p:AC 103 90 0.5604 0.4951 0.5667 7.86e-25 4v8p:DC, 4v8p:FC, 4v8p:HC
13 3j79:i 95 92 0.5824 0.5579 0.5761 1.60e-24 3jbn:Ai, 3jbo:Ai, 3jbp:Ai, 8tpu:Ai, 5umd:i
14 7r81:q1 105 93 0.5714 0.4952 0.5591 4.01e-24 7olc:Lo, 7old:Lo, 8oo0:Lo, 7z3n:Lo, 7z3o:Lo
15 4v6i:Br 106 93 0.5495 0.4717 0.5376 8.95e-23 8aaf:b, 8agt:b, 8agu:b, 8agv:b, 8agw:b, 8agx:b, 8agz:b, 5apn:o, 5apo:o, 7azy:Q, 7b7d:Lk, 8bip:Lo, 8bjq:Lo, 8bn3:Q2, 8bqd:AP, 8bqx:AP, 8c3a:AP, 8c3a:CJ, 8ccs:a, 8cdl:a, 8cdr:a, 8ceh:a, 8cf5:a, 8cg8:a, 8cgn:a, 8civ:a, 8cku:a, 8cmj:a, 8cq7:AP, 8cq7:CJ, 8cqw:AP, 8cqw:CJ, 8cre:AP, 8cre:CJ, 5dat:Q2, 5dat:q2, 5dc3:Q2, 5dc3:q2, 5dge:Q2, 5dge:q2, 5dgf:Q2, 5dgf:q2, 5dgv:Q2, 5dgv:q2, 8eub:Ao, 8evp:Ao, 8evq:Ao, 8evr:Ao, 8evs:Ao, 8evt:Ao, 8ewb:Ao, 8ewc:Ao, 5fci:Q2, 5fci:q2, 5fcj:Q2, 5fcj:q2, 5gak:C, 6gq1:o, 6gqb:o, 6gqv:o, 5h4p:o, 6hd7:C, 8hfr:mS, 6hhq:AP, 6hhq:DQ, 5i4l:Q2, 5i4l:q2, 6i7o:AP, 6i7o:XP, 5it7:oo, 3j0l:F, 3j0o:F, 3j6x:82, 3j6y:82, 3j77:92, 3j78:92, 5juo:TA, 5jup:TA, 5jus:TA, 5jut:TA, 5juu:TA, 8k2d:Lo, 8k82:Lo, 5lyb:Q2, 5lyb:q2, 5m1j:o5, 5mc6:AP, 5mei:AP, 5mei:DQ, 7mpi:Ao, 7mpj:Ao, 6n8j:q, 6n8k:q, 6n8l:q, 6n8m:Q, 6n8n:Q, 6n8o:Q, 7n8b:Ao, 5ndg:Q2, 5ndg:q2, 5ndv:Q2, 5ndv:q2, 5ndw:Q2, 5ndw:q2, 7nrc:Lq, 7nrd:Lq, 5obm:Q2, 5obm:q2, 8oeq:AP, 8oeq:CJ, 6oig:o, 5on6:AP, 5on6:DQ, 7osa:eL42, 7osm:eL42, 8p8m:RQ, 8p8n:RQ, 8p8u:RQ, 8pfr:RQ, 7pzy:AP, 7q08:AP, 7q0f:AP, 7q0p:AP, 7q0r:AP, 8q5i:AP, 6q8y:AP, 6qik:l, 6qt0:l, 6qtz:l, 6r84:C, 6r86:C, 6r87:C, 6ri5:l, 7rr5:Lo, 6rzz:l, 6s05:l, 6s47:Aq, 6snt:ab, 6sv4:AP, 6sv4:XP, 6sv4:zP, 6t4q:Lo, 5t62:Q, 5t6r:Q, 6t7i:Lo, 6t7t:Lo, 6t83:ob, 6t83:Z, 5tbw:AP, 5tbw:DQ, 6tb3:AP, 5tga:Q2, 5tga:q2, 5tgm:Q2, 5tgm:q2, 6tnu:AP, 7too:AL42, 7top:AL42, 4u3m:Q2, 4u3m:q2, 4u3n:Q2, 4u3n:q2, 4u3u:Q2, 4u3u:q2, 4u4n:Q2, 4u4n:q2, 4u4o:Q2, 4u4o:q2, 4u4q:Q2, 4u4q:q2, 4u4r:Q2, 4u4r:q2, 4u4u:Q2, 4u4u:q2, 4u4y:Q2, 4u4y:q2, 4u4z:Q2, 4u4z:q2, 4u50:Q2, 4u50:q2, 4u51:Q2, 4u51:q2, 4u52:Q2, 4u52:q2, 4u53:Q2, 4u53:q2, 4u55:Q2, 4u55:q2, 4u56:Q2, 4u56:q2, 4u6f:Q2, 4u6f:q2, 6uz7:Bo, 4v4b:BZ, 4v7h:BZ, 4v7r:Bf, 4v7r:Df, 4v88:Bo, 4v88:Do, 4v8t:o, 4v8y:Bo, 4v8z:Bo, 4v91:o, 6woo:o, 6xiq:o, 6xir:o, 8y0u:Lo, 7z34:q, 6z6j:Lo, 6z6k:Lo, 7zpq:Bn, 7zrs:Bn, 7zs5:BA, 7zuw:Bn, 7zux:En, 7zw0:Lr
16 8eui:o 98 93 0.5604 0.5204 0.5484 1.64e-22 8eug:o
17 6zj3:L4 97 93 0.4945 0.4639 0.4839 2.15e-14
18 8hku:L44E 92 90 0.3956 0.3913 0.4000 1.30e-13 8hkv:L44E, 8hky:L44E, 8hkz:L44E, 8hl1:L44E, 8hl2:L44E, 8hl3:L44E, 8hl4:L44E, 8hl5:L44E
19 5xy3:o 93 74 0.3187 0.3118 0.3919 1.30e-11
20 4v4n:Aj 94 78 0.3187 0.3085 0.3718 8.59e-11 6skf:Bl, 6skg:Bl, 6th6:Bl, 4v6u:Bj
21 3cc2:3 92 91 0.2967 0.2935 0.2967 2.81e-05 3cc4:3, 3cc7:3, 3cce:3, 3ccj:3, 3ccl:3, 3ccm:3, 3ccq:3, 3ccr:3, 3ccs:3, 3ccu:3, 3ccv:3, 3cd6:3, 3cma:3, 3cme:3, 3cpw:2, 3cxc:2, 1ffk:Z, 3g4s:3, 3g6e:3, 3g71:3, 3i55:3, 3i56:3, 1jj2:2, 1k73:4, 1k8a:4, 1k9m:4, 1kc8:4, 1kd1:4, 1kqs:2, 1m1k:4, 1m90:4, 1n8r:4, 1nji:4, 2otj:3, 2otl:3, 3ow2:2, 1q7y:4, 1q81:4, 1q82:4, 1q86:4, 2qa4:3, 2qex:3, 1qvf:2, 1qvg:2, 1s72:3, 4v9f:3, 1vq4:3, 1vq5:3, 1vq6:3, 1vq7:3, 1vq8:3, 1vq9:3, 1vqk:3, 1vql:3, 1vqm:3, 1vqn:3, 1vqo:3, 1vqp:3, 1w2b:2, 1yhq:3, 1yi2:3, 1yij:3, 1yit:3, 1yj9:3, 1yjn:3, 1yjw:3
22 5xwm:D 368 50 0.1538 0.0380 0.2800 3.1 5xwm:A, 5xwm:C, 5xwm:B
23 5l58:A 376 25 0.1209 0.0293 0.4400 7.1
24 6ajc:A 413 25 0.1099 0.0242 0.4000 7.7 6ajc:B, 6ajc:C, 6ajc:D, 6ajc:E, 6ajc:F, 6ajc:G, 6ajc:H
25 6adg:C 390 25 0.1209 0.0282 0.4400 9.5
26 1o0s:A 602 56 0.1868 0.0282 0.3036 9.9 1llq:A, 1llq:B, 1o0s:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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