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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VHVVSRNAEGVIVVDGKAYPMAEELVATESVIQRSIKAVAKQIADFYRPLSHRDTHGGGGVAPISDENPLIIISVLKGSY
IFTADMVRYLGDYGLPHVVDFLRVASQLLAETQFKALRGKHVLILEDIVDSGKTLRYILDKVQREHQPATLKVCVLADKP
GGRRVTMQPDFVCLTVPNKYVIGYGFEVNDRFRCFRHIFTLRPGEARRYPAHL

The query sequence (length=213) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8fx3:B 223 223 1.0000 0.9552 0.9552 3.05e-155 8fwy:A, 8fwy:B, 8fwz:A, 8fwz:B, 8fx0:A, 8fx0:B, 8fx1:A, 8fx1:B, 8fx2:A, 8fx2:B, 8fx3:A
2 6mxc:C 220 218 0.6244 0.6045 0.6101 8.92e-100 6aqo:A, 6aqo:B, 6aqo:C, 6aqo:D, 6aqo:E, 6aqo:F, 6ar9:A, 6ar9:B, 6ar9:C, 6ar9:D, 6ar9:E, 6ar9:F, 6mxb:A, 6mxb:B, 6mxb:C, 6mxb:D, 6mxb:E, 6mxb:F, 6mxc:A, 6mxc:B, 6mxc:D, 6mxc:E, 6mxc:F, 6mxd:A, 6mxd:B, 6mxd:C, 6mxd:D, 7scr:A, 7scr:C, 7scr:B, 7scr:D, 7scr:E, 7scr:F
3 6aps:A 185 186 0.3521 0.4054 0.4032 1.97e-43 6aps:B, 6apt:A, 6apt:B, 6apu:A, 6apu:B, 6apv:A, 6apv:B, 6apv:C, 6apv:D, 5jsq:A, 5jsq:B, 5jv5:A, 5jv5:B, 5k51:A, 5k51:B, 5k51:C, 5k51:D, 5kam:A, 5kam:C, 5kap:A, 5kap:B, 6mxg:A, 6mxg:B, 7sb7:A, 7sb7:B, 8tr1:A, 8tr1:B, 8tr1:C, 8tr1:D, 8ts4:A, 8ts4:B
4 1p17:B 204 192 0.3803 0.3971 0.4219 5.22e-41 1i0i:A, 1i0i:B, 1i0l:A, 1i0l:B, 1i13:A, 1i13:B, 1i14:A, 1i14:B, 1p17:A, 1p17:C, 1p17:D, 1p18:A, 1p18:B, 1p19:A, 1p19:B, 1p19:C, 1p19:D, 1tc1:A, 1tc1:B, 1tc2:A, 1tc2:B
5 7cmj:A 184 195 0.3192 0.3696 0.3487 2.65e-35 1pzm:A, 1pzm:B
6 1bzy:A 214 158 0.2535 0.2523 0.3418 2.67e-24 6bnj:A, 6bnj:B, 6bnj:C, 6bnj:D, 5brn:A, 5brn:C, 5brn:D, 1bzy:B, 1bzy:C, 1bzy:D, 1d6n:A, 1d6n:B, 3gep:A, 3gep:B, 3ggc:A, 3ggc:B, 3ggj:A, 3ggj:B, 5hia:A, 5hia:B, 5hia:C, 5hia:D, 1hmp:A, 1hmp:B, 4ijq:A, 4ijq:B, 4ijq:C, 4ijq:D, 4rab:A, 4rab:B, 4rab:C, 4rab:D, 4rac:A, 4rac:B, 4rac:C, 4rac:D, 4rad:A, 4rad:B, 4rad:C, 4rad:D, 4rad:E, 4rad:F, 4rad:G, 4rad:H, 4ran:A, 4ran:B, 4ran:C, 4ran:D, 4rao:A, 4rao:B, 4rao:C, 4rao:D, 4raq:A, 4raq:B, 4raq:C, 4raq:D, 7san:A, 7san:B, 7san:C, 7san:D, 8tpv:A, 8tpv:B, 8tpv:C, 8tpv:D, 5w8v:A, 5w8v:B, 5w8v:C, 5w8v:D
7 1hgx:A 164 172 0.2535 0.3293 0.3140 6.55e-24
8 4qyi:B 171 176 0.2535 0.3158 0.3068 1.84e-23 4qyi:A, 4qyi:C, 4qyi:D, 4qyi:E
9 5brn:B 194 148 0.2488 0.2732 0.3581 7.66e-23 5bsk:A, 5bsk:B, 5bsk:C, 5bsk:D, 4kn6:A, 8tpy:A, 8tpy:B, 8tpy:C, 8tpy:D
10 3kb8:A 201 191 0.2629 0.2786 0.2932 1.33e-21 6d9r:A, 6d9r:B, 6d9s:A, 6d9s:B, 3h83:A, 3h83:B, 3kb8:B
11 5knx:B 176 171 0.2347 0.2841 0.2924 1.94e-21 1g9s:A, 1g9s:B, 1g9t:A, 1g9t:B, 1grv:B, 1grv:A, 1j7j:A, 1j7j:B, 5knr:A, 5knr:B, 5kns:A, 5kns:B, 5knt:A, 5knt:B, 5knu:A, 5knu:B, 5knv:A, 5knv:B, 5knx:A
12 2vfa:B 205 149 0.2300 0.2390 0.3289 6.80e-21 2vfa:A
13 2geb:A 184 191 0.2676 0.3098 0.2984 1.53e-20 1r3u:A, 1r3u:B, 1yfz:A, 1yfz:B
14 3acc:A 166 132 0.2207 0.2831 0.3561 3.82e-20 3acd:A
15 5kny:B 187 191 0.2770 0.3155 0.3089 7.98e-20 5knp:A, 5knp:B, 5knp:C, 5knp:D, 5knq:A, 5knq:B, 5knq:C, 5knq:D, 5kny:A, 5kny:C, 5kny:D, 4rht:A, 4rht:B, 4rht:C, 4rht:D, 4rhu:A, 4rhu:B, 4rhu:C, 4rhu:D, 4rhu:E, 4rhu:F, 4rhx:A, 4rhx:B, 4rhx:C, 4rhx:D, 4rhy:A, 4rhy:B, 4rhy:C, 4rhy:D
16 2jbh:B 213 156 0.2254 0.2254 0.3077 3.75e-19 2jbh:A
17 6igs:B 167 130 0.1972 0.2515 0.3231 1.98e-17 6igs:A, 6igs:C, 6igs:D
18 4pfq:C 184 145 0.2019 0.2337 0.2966 1.36e-15 4pfq:A, 4pfq:B, 4pfq:D, 4pfq:E, 4pfq:F, 4pfq:G, 4pfq:H
19 5ipf:A 201 185 0.2441 0.2587 0.2811 1.01e-14 5ipf:B, 5ipf:C, 5ipf:D
20 6bo7:A 220 136 0.1925 0.1864 0.3015 3.20e-13 6bo7:B, 6bo7:C, 6bo7:D, 6bo7:E, 6bo7:F, 6bo7:G, 6bo7:H, 6bo7:I, 6bo7:J, 6bo7:K, 6bo7:L
21 1fsg:A 233 158 0.2019 0.1845 0.2722 7.10e-11 1dbr:A, 1dbr:B, 1dbr:D, 1fsg:C, 1qk3:A, 1qk3:B, 1qk3:C, 1qk3:D, 1qk4:A, 1qk4:B, 1qk4:C, 1qk4:D, 1qk5:A, 1qk5:B
22 3ozf:B 234 103 0.1455 0.1325 0.3010 1.88e-10 1cjb:A, 1cjb:B, 1cjb:C, 1cjb:D, 3ozf:A, 3ozf:C, 3ozf:D, 3ozg:A, 3ozg:B, 3ozg:C, 3ozg:D, 7tux:A, 7tux:B, 7tux:C, 7tux:D
23 5esw:A 190 154 0.2019 0.2263 0.2792 1.16e-07 5esx:A, 5esx:B
24 1dqn:A 230 165 0.1784 0.1652 0.2303 5.49e-05 1dqn:B, 1dqp:A, 1dqp:B
25 2igb:B 173 59 0.0892 0.1098 0.3220 6.19e-04 2igb:A, 4p83:A, 4p83:B, 4p83:C, 4p83:D, 1xz8:A, 1xz8:B, 1xzn:A, 1xzn:B
26 4zfn:B 177 67 0.1033 0.1243 0.3284 0.002 5bqp:A, 5bqp:B, 5bqp:C, 5bqp:D, 4z1o:A, 4z1o:B, 4zfn:A
27 5iao:A 171 58 0.0798 0.0994 0.2931 0.007 5iao:C, 5iao:F
28 1z5x:E 237 135 0.1690 0.1519 0.2667 0.098
29 4p86:A 177 58 0.0657 0.0791 0.2414 0.099 4p86:B, 4p86:C, 4p86:D
30 5vog:A 176 173 0.2066 0.2500 0.2543 0.23
31 7e0d:A 604 39 0.0563 0.0199 0.3077 0.96 7e0c:A, 2e1m:A, 2e1m:B, 2e1m:C, 8jpw:A
32 4trb:B 209 56 0.0798 0.0813 0.3036 1.2 4trc:A, 4trc:B, 4ts5:A, 4ts5:B, 4ts7:A, 4ts7:B
33 2jky:A 207 98 0.1174 0.1208 0.2551 1.4 2jky:B, 2jkz:A, 2jkz:B, 2jkz:C, 2jkz:D, 2xbu:A, 2xbu:B
34 8c8v:A 1032 86 0.1221 0.0252 0.3023 1.5 8c8u:A, 8c8w:A, 8c9d:A
35 2reg:A 290 60 0.0892 0.0655 0.3167 1.5 2reg:B, 2rin:A, 2rin:B
36 2wns:B 199 45 0.0657 0.0704 0.3111 1.6 2wns:A
37 5u30:A 1085 96 0.1268 0.0249 0.2812 1.9 5u31:A, 5u33:A
38 4dmg:A 385 81 0.1315 0.0727 0.3457 2.0 4dmg:B
39 9cf1:P 726 99 0.1408 0.0413 0.3030 4.0 9cf0:P, 9cf2:P, 9cf3:P
40 4gpu:A 331 50 0.0704 0.0453 0.3000 6.2
41 3kw0:B 197 61 0.0798 0.0863 0.2787 7.2 3kw0:A, 3kw0:C, 3kw0:D
42 1a95:B 150 97 0.1315 0.1867 0.2887 7.6 1a95:C, 1a96:B, 1a96:C, 1a97:B, 1a97:C, 4jit:B, 4jit:C
43 7ayx:B 396 81 0.1174 0.0631 0.3086 9.7 7ayx:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218