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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VEVIFYLSDREPLRLGSGEYTAEELCIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVMSLRLHYRMRFYFTNWHG
TNDNEQSVWRHSPTPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQDGHDIENECLGMAVLAISHYAMMKKMQLPELPI
SYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISS
ENEMNWFHSLYYEVMVTGNLGIQWRHKPNEEWNNFSFFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDG
YFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEYVLRWSCTDFDNILIEVQKRYSLHGSDRSFPSLGD
LMSHLCQPKPREISNLLVAT

The query sequence (length=420) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5ixi:A 436 444 0.9810 0.9450 0.9279 0.0 5ixd:A
2 8ewy:A 1049 468 0.9452 0.3785 0.8483 0.0 6aah:A, 6aah:B, 6bbu:A, 6c7y:A, 6dbn:A, 5e1e:A, 5e1e:B, 4e4l:A, 4e4l:E, 4e4l:B, 4e4l:D, 4e4n:A, 4e4n:B, 4e5w:A, 4e5w:B, 4ehz:A, 4ehz:B, 4ehz:C, 4ehz:D, 4ei4:A, 4ei4:B, 6elr:A, 6elr:B, 8ewy:B, 3eyg:A, 3eyh:A, 4fk6:A, 4fk6:B, 6ggh:A, 6ggh:B, 5hx8:A, 5hx8:B, 6hzu:A, 6hzu:B, 4i5c:A, 4i5c:B, 4ivb:A, 4ivb:B, 4ivc:A, 4ivc:B, 4ivd:A, 4ivd:B, 4k6z:A, 4k77:A, 4k77:B, 5khw:A, 5khw:B, 5khx:A, 6n77:A, 6n77:B, 6n78:A, 6n79:A, 6n7a:A, 6n7a:B, 6n7b:A, 6n7c:A, 6n7c:B, 6n7d:A, 6rsb:A, 6rsb:B, 6rsc:A, 6rsc:B, 6rsd:A, 6rsd:B, 6rse:A, 6rse:B, 6rsh:A, 6rsh:B, 6sm8:A, 6sm8:B, 6smb:A, 6smb:B, 7t6f:A, 7t6f:B, 6tpe:A, 6tpe:B, 6tpf:A, 6tpf:B, 6w8l:A, 5wo4:A, 5wo4:B
3 4po6:A 475 453 0.4333 0.3832 0.4018 9.65e-98
4 6e2p:A 457 469 0.4286 0.3939 0.3838 1.55e-86 6e2p:B
5 8c6j:o 513 64 0.0429 0.0351 0.2812 0.70 7a5p:E, 6ff4:E, 9fmd:W, 6icz:W, 6id0:W, 6id1:W, 5mqf:E, 6qdv:o, 8ro2:W, 7w59:W, 7w5a:W, 7w5b:W, 5xjc:W, 6zym:E
6 8i0w:W 440 64 0.0429 0.0409 0.2812 0.88 5yzg:W
7 5ech:A 569 177 0.0881 0.0650 0.2090 2.4 5ech:D, 5eci:A, 5eci:D, 5eck:A, 5eck:D, 5ecl:A, 5ecl:D, 5ecm:A, 5ecm:D, 5ecn:A, 5ecn:D, 5eco:A, 5eco:D, 5ecp:A, 5ecp:D, 5ecq:A, 5ecq:D, 5ecr:A, 5ecr:D, 4epl:A, 5gzz:A
8 3ei9:A 412 43 0.0381 0.0388 0.3721 5.3 3ei5:A, 3ei5:B, 3ei6:A, 3ei6:B, 3ei8:A, 3ei8:B, 3ei9:B, 3eia:A, 3eia:B, 3eib:A, 3eib:B, 2z1z:A, 2z1z:B, 2z20:A, 2z20:B
9 5hdp:D 316 33 0.0333 0.0443 0.4242 9.0 5hdp:A, 5hdp:B, 5hdp:C, 5hdp:E, 5hdp:F, 5hdp:G
10 7knv:A 126 63 0.0405 0.1349 0.2698 10.0 6ppo:U

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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