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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VADSRLPNFRALTPAQRRDFLADACGLSDAERALLAAPGALPLALADGMIENVFGSFELPLGVAGNFRVNGRDVLVPMAV
EEPSVVAAASYMAKLAREDGGFQTSSTLPLMRAQVQVLGVTDPHGARLAVLQARAQIIERANSRDKVLIGLGGGCKDIEV
HVFPDTPRGPMLVVHLIVDVRDAMGANTVNTMAESVAPLVEKITGGSVRLRILSNLADLRLARARVRLTPQTLATQDRSG
EEIIEGVLDAYTFAAIDPYRAATHNKGIMNGIDPVIVATGNDWRAVEAGAHAYASRSGSYTSLTRWEKDAGGALVGSIEL
PMPVGLVGGATKTHPLARLALKIMDLQSAQQLGEIAAAVGLAQNLGALRALATEGI

The query sequence (length=376) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6dio:C 428 376 1.0000 0.8785 1.0000 0.0 6dio:A, 6dio:B, 6eev:A
2 6p7k:A 375 372 0.7739 0.7760 0.7823 0.0
3 1qax:A 425 374 0.7261 0.6424 0.7299 0.0 8gdn:A, 8gdn:B, 4i4b:A, 4i4b:B, 4i56:A, 4i56:B, 4i6a:A, 4i6a:B, 4i6w:A, 4i6w:B, 4i6y:A, 4i6y:B, 1qax:B, 1qay:A, 1qay:B, 1r31:A, 1r31:B, 8sz6:A, 8sz6:B, 1t02:A, 8vlq:A, 8vlq:B
4 5wpk:B 422 369 0.4016 0.3578 0.4092 2.06e-87 5wpj:A, 5wpk:A
5 7m1z:B 425 371 0.4043 0.3576 0.4097 5.36e-78 7m1z:A, 7m1z:C, 7m1z:D, 7m3h:A, 7m3h:B, 7m66:A, 7m66:C, 7m66:B, 7m66:D
6 6hr8:A 397 354 0.2287 0.2166 0.2429 1.81e-04 6hr8:B, 6hr8:C, 6hr8:D, 6hr8:E, 6hr8:F
7 3cd5:A 425 41 0.0426 0.0376 0.3902 0.073 3bgl:A, 3bgl:B, 3bgl:C, 3bgl:D, 3cct:A, 3cct:B, 3cct:C, 3cct:D, 3ccw:A, 3ccw:B, 3ccw:C, 3ccw:D, 3ccz:A, 3ccz:B, 3ccz:C, 3ccz:D, 3cd0:A, 3cd0:B, 3cd0:C, 3cd0:D, 3cd5:B, 3cd5:C, 3cd5:D, 3cd7:A, 3cd7:B, 3cd7:C, 3cd7:D, 3cda:A, 3cda:B, 3cda:C, 3cda:D, 3cdb:A, 3cdb:B, 3cdb:C, 3cdb:D, 1dq8:A, 1dq8:B, 1dq8:C, 1dq8:D, 1dq9:A, 1dq9:B, 1dq9:C, 1dq9:D, 1dqa:A, 1dqa:B, 1dqa:C, 1dqa:D, 1hw8:A, 1hw8:B, 1hw8:C, 1hw8:D, 1hw9:A, 1hw9:B, 1hw9:C, 1hw9:D, 1hwi:A, 1hwi:B, 1hwi:C, 1hwi:D, 1hwj:A, 1hwj:B, 1hwj:C, 1hwj:D, 1hwk:A, 1hwk:B, 1hwk:C, 1hwk:D, 1hwl:A, 1hwl:B, 1hwl:C, 1hwl:D, 2q1l:A, 2q1l:B, 2q1l:C, 2q1l:D, 2q6b:A, 2q6b:B, 2q6b:C, 2q6b:D, 2q6c:A, 2q6c:B, 2q6c:C, 2q6c:D, 2r4f:A, 2r4f:B, 2r4f:C, 2r4f:D
8 8ecg:A 357 158 0.1117 0.1176 0.2658 0.14
9 4ojv:A 363 118 0.0878 0.0909 0.2797 0.31 4ojx:A
10 7pwe:A 194 70 0.0505 0.0979 0.2714 1.4 7pwe:B
11 5das:A 198 108 0.0798 0.1515 0.2778 2.0 6buv:B, 4s1o:A, 4ybr:A, 4ybr:B
12 3d43:B 310 128 0.0878 0.1065 0.2578 3.5 3d43:A, 1ea7:A, 2ixt:A, 2ixt:B
13 6k8t:A 662 75 0.0665 0.0378 0.3333 3.9 6k8t:B, 6k8u:A, 6k8u:B
14 8irm:A 540 93 0.0638 0.0444 0.2581 4.2 8irm:B, 8irn:A, 8irn:B, 8iro:B, 8iro:A, 8irp:B, 8irp:A, 8wmq:B, 8wmq:A
15 3zjh:B 193 67 0.0612 0.1192 0.3433 7.1 3qzx:A, 3qzz:A, 3r0g:A, 3r0g:B, 2veb:A, 2vee:A, 2vee:B, 2vee:C, 2vee:D, 2vee:E, 2vee:F, 2vee:G, 2vee:H, 3zh0:A, 3zh0:B, 3zh0:C, 3zh0:D, 3zjh:A, 3zji:A, 3zji:B, 3zjj:A, 3zjj:B, 3zjj:C, 3zjl:A, 3zjl:B, 3zjm:A, 3zjm:B, 3zjm:C, 3zjn:A, 3zjn:B, 3zjo:A, 3zjo:B, 3zjp:A, 3zjq:A, 3zjq:B, 3zjr:A, 3zjs:A, 3zjs:B, 3zol:A, 3zol:B, 3zom:A, 3zom:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218