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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TTAKQAEAVEDSDINPWTGQRHSERYFKILKARRKLPVNKQRQEFLDLYHNNQILVFVGETGSGKTTQIPQYVLYDELPH
QTGKLIACTQPRRVAAMSVAQRVADELDVKLGEEVGYSIRFENKTSSKTLLKYMTDGQLLREAMHDRDMSRYSCIILDEA
HERTLATDILMALLKQLSERRKDLKIIVMSATLDAQKFQSYFFNAPLLAVPGRTHPVEIFYTPEAERDYVEAAIRTVLQI
HACEPEGDILLFLTGEEEIEDACRRISLEVDEMIRESDAGPMSVYPLYGTLPPHQQQRIFEKAPQPFRPGGRPGRKCIVA
TNIAETSLTIDGIVYVVDPGFSKQKIYNPRTRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFKKELIEQTYP
EILRSNLSNTVLELKKLGVEDLVHFDLMDPPAPETMMRALEELNYLACLDDDGELTPLGNLASEFPLDPALAVMLISSPE
FYCSNEILSITSLLSVPQIWVRPANARKRADEMKAQFAHPDGDHLTLLNAYHAYKGAEARGEDMKKWCHEHFLSYRHLSS
ADNVRAQLKKIMETHGIELVSTPFHDKNYYTNIRRALLAGFFMQVAMRESSNSKVYKTVKDEQLVLIHPSTTVTTPYEWV
VYNEFVLTTKQYVRTVTNIRPEWLLEIAPVYYDLSTFQKGEIKNALTRVAEKIRRQQAMK

The query sequence (length=700) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5d0u:A 705 700 1.0000 0.9929 1.0000 0.0 5lta:A, 5ltj:A, 5ltk:A, 6qid:A, 6qie:A
2 3kx2:B 755 700 0.7186 0.6662 0.7186 0.0 5i8q:A, 5i8q:B, 5jpt:A, 5jpt:B, 3kx2:A, 2xau:A, 2xau:B, 5y88:W
3 6sh6:A 681 684 0.6243 0.6417 0.6389 0.0 8ejm:A, 8ro2:DX, 5xdr:A
4 8ro1:DX 682 688 0.6143 0.6305 0.6250 0.0
5 8c6j:V 934 648 0.4614 0.3458 0.4985 0.0 6hys:A, 6hys:B, 6hys:C, 6hys:D, 6hyt:A, 6hyt:B, 6hyt:C, 6hyt:D, 6hyu:A
6 6i3p:C 630 652 0.4743 0.5270 0.5092 0.0 6i3p:A, 6i3p:B, 6i3p:D, 6qic:A, 6qic:B, 6qic:C, 6qic:D
7 8i0s:X 786 653 0.4671 0.4160 0.5008 0.0 8i0t:X, 8i0u:X, 8i0v:X
8 7qtt:N 792 653 0.4657 0.4116 0.4992 0.0 8ch6:N
9 6bk8:P 653 651 0.4514 0.4839 0.4854 0.0 6exn:V, 5mq0:V
10 8cnt:A 620 640 0.4329 0.4887 0.4734 0.0
11 6rm8:A 655 649 0.4471 0.4779 0.4823 0.0 6fa5:A, 6faa:A, 6fac:A, 6rm9:A, 6rma:A, 6rmb:A, 6rmc:A, 6rmc:B, 6zm2:A
12 6hyu:C 585 637 0.4271 0.5111 0.4694 0.0
13 7b9v:Q 624 650 0.4100 0.4599 0.4415 4.78e-173
14 5gm6:Y 598 653 0.4043 0.4732 0.4334 2.21e-169
15 7dcp:x 670 673 0.4014 0.4194 0.4175 2.48e-168 7dco:x, 7dd3:x
16 6zww:C 749 648 0.3400 0.3178 0.3673 2.10e-134 8po7:B, 8po8:A, 8po8:B, 6zww:A, 6zww:E, 6zww:G
17 8po7:A 594 564 0.3057 0.3603 0.3794 8.66e-117
18 6zqg:JD 829 695 0.3529 0.2979 0.3554 3.37e-116
19 6h57:A 795 634 0.3329 0.2931 0.3675 6.51e-113
20 7aju:JD 811 607 0.3271 0.2824 0.3773 9.07e-112 6zqd:JD, 6zqe:JD, 6zqf:JD
21 5vhe:A 871 720 0.3371 0.2710 0.3278 3.25e-104 6up3:A, 6up4:A, 5vhc:D, 5vhd:D
22 7mqa:NS 914 663 0.3329 0.2549 0.3514 1.91e-102 6o16:A, 6o16:B
23 5n9d:B 866 691 0.3200 0.2587 0.3242 1.14e-91 5n8r:A, 5n8r:B, 5n8s:A, 5n8s:B, 5n8u:A, 5n8u:B, 5n8z:A, 5n8z:B, 5n90:A, 5n90:B, 5n94:A, 5n94:B, 5n96:A, 5n96:B, 5n98:A, 5n98:B, 5n9a:A, 5n9a:B, 5n9d:A, 5n9e:A, 5n9e:B, 5n9f:A, 5n9f:B
24 8pjb:A 962 732 0.3000 0.2183 0.2869 8.29e-77 8b9g:A, 8b9k:A, 8pjj:A
25 8szq:A 861 592 0.2600 0.2114 0.3074 3.70e-76 3llm:A, 3llm:B, 8szp:A, 8szp:B, 8szr:A, 8szs:A
26 5aor:A 1009 744 0.3043 0.2111 0.2863 9.78e-74 5aor:B, 8b9i:A, 8b9j:A
27 6heg:A 783 444 0.2257 0.2018 0.3559 1.22e-61
28 7d63:RZ 839 263 0.1571 0.1311 0.4183 8.52e-52 7d4i:RZ, 7d5t:RZ, 7mqj:A
29 7d63:RZ 839 350 0.1743 0.1454 0.3486 7.77e-49 7d4i:RZ, 7d5t:RZ, 7mqj:A
30 8arp:C 445 365 0.1143 0.1798 0.2192 0.060 8arp:A, 8arp:B, 8arp:D, 8arp:E, 8arp:F
31 8bns:A 433 62 0.0314 0.0508 0.3548 0.56 8bns:B, 8bns:C, 8bns:D
32 6yba:N 298 110 0.0386 0.0906 0.2455 0.83 6z7n:O
33 5jcs:s 2003 118 0.0443 0.0155 0.2627 1.1
34 5jcs:s 2003 51 0.0243 0.0085 0.3333 8.5
35 7m1q:A 1911 90 0.0357 0.0131 0.2778 1.3
36 6l5n:A 377 157 0.0571 0.1061 0.2548 1.7 6l5m:A, 6l5m:B, 6l5m:C, 6l5m:D, 6l5m:E, 6l5n:B, 6l5o:A
37 8q87:A 857 100 0.0357 0.0292 0.2500 1.7 6d9j:9, 6gz3:Ct, 6gz4:Ct, 6gz5:Ct, 3j7p:4, 7ls1:m, 7ls2:m, 6mtd:v, 6mte:v, 7oyc:v2, 4v6x:Az, 8xsx:CB, 6z6m:CB, 6z6n:CB
38 8f5b:A 1924 103 0.0400 0.0146 0.2718 2.2 7lkz:A
39 7e7o:A 2003 85 0.0329 0.0115 0.2706 2.2 7lkp:A
40 7e7q:A 1958 85 0.0329 0.0117 0.2706 2.4
41 7v4r:A 437 93 0.0371 0.0595 0.2796 2.9
42 7r8q:B 389 135 0.0400 0.0720 0.2074 2.9 7r8p:A, 7r8q:A
43 3s4y:A 224 62 0.0257 0.0804 0.2903 3.5 3s4y:B
44 3aoh:I 1289 167 0.0629 0.0341 0.2635 5.3 3aoi:I
45 2a68:D 1392 167 0.0629 0.0316 0.2635 5.5 2a68:N, 2a69:D, 2a69:N, 2a6e:D, 2a6e:N, 2a6h:D, 2a6h:N, 2be5:D, 2be5:N, 2cw0:D, 2cw0:N, 1iw7:D, 1iw7:N, 1smy:D, 1smy:N, 1zyr:D, 1zyr:N
46 6upq:A 270 192 0.0657 0.1704 0.2396 5.5 3ftq:A, 7m6j:F, 6upr:A
47 2o5j:D 1264 167 0.0629 0.0348 0.2635 5.6 2o5j:N
48 8wbx:B 467 120 0.0414 0.0621 0.2417 5.9
49 3dxj:D 1504 167 0.0629 0.0293 0.2635 6.0 6cuu:D, 5d4c:D, 5d4c:N, 5d4d:D, 5d4d:N, 5d4e:D, 5d4e:N, 3dxj:N, 5e17:D, 5e18:D, 7eh0:D, 7eh1:D, 7eh2:D, 7eh2:N, 4g7h:D, 4g7h:N, 4g7o:D, 4g7o:N, 4g7z:D, 4g7z:N, 6kqd:D, 6kqd:N, 6kqe:D, 6kqf:D, 6kqg:D, 6kqh:D, 6kql:D, 6kqm:D, 6kqn:D, 6l74:D, 6lts:D, 7mlb:D, 7mli:D, 7mlj:D, 4oin:D, 4oio:D, 4oip:D, 4oiq:D, 4oir:D, 6ovr:D, 6ovy:D, 6ow3:D, 6oy5:D, 6oy6:D, 6oy7:D, 6p70:D, 6p71:D, 4q4z:D, 4q5s:D, 5tmc:D, 5tmf:D, 5vo8:D, 5voi:D, 8w8n:D, 8w8o:D, 8w8p:D, 3wod:D, 6wox:D, 6woy:D, 5x21:D, 5x22:N, 5xj0:D, 4xln:D, 4xlp:D, 4xlq:D, 4xlr:D, 4xls:D, 1ynj:D, 1ynn:D
50 3kxa:A 131 33 0.0214 0.1145 0.4545 6.0 3kxa:B, 3kxa:C, 3kxa:D
51 4wqs:N 1288 167 0.0629 0.0342 0.2635 6.1
52 4wqs:D 1151 167 0.0629 0.0382 0.2635 6.3
53 3eql:D 1321 167 0.0629 0.0333 0.2635 6.5 3eql:N, 8hsg:J, 8hsh:J, 8hsl:J, 8hsr:J, 6m6a:D, 6m6b:D, 6m6c:D, 2o5i:D, 2o5i:N, 2ppb:D, 2ppb:N
54 2dre:C 177 58 0.0271 0.1073 0.3276 6.7 2dre:A, 2dre:B, 2dre:D, 6giw:A, 6giw:B, 6giw:C, 6giw:D, 6gix:A, 6gix:B, 6gix:C, 6gix:D, 6s2y:A, 6s2y:B, 6s2y:D, 6s2y:C
55 6j5w:A 816 82 0.0343 0.0294 0.2927 7.0 6j5t:G, 6j5t:C, 6j5t:F, 6j5t:L, 6j5t:O, 6j6i:C, 6j6i:F, 6j6i:G, 6j6i:L, 6j6i:O
56 6def:C 368 78 0.0357 0.0679 0.3205 9.1 6def:A, 6def:B, 6def:D, 6di7:A, 6djq:A, 6djq:C, 6djq:D, 6vjf:A, 6vjf:B, 6vjf:C, 6vjf:D
57 5jbj:A 627 71 0.0300 0.0335 0.2958 9.4

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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