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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TSFSILMSPFVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGAT
VDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPSNT
YKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGF
GIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSKLRQLLFNK

The query sequence (length=286) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7wu4:R 286 286 1.0000 1.0000 1.0000 0.0 7wu3:R, 7wu5:R
2 8g2y:R 251 282 0.8776 1.0000 0.8901 5.72e-168
3 6pb0:R 281 269 0.2413 0.2456 0.2565 1.06e-12 8gtg:A, 8gti:A, 8gtm:A, 4k5y:C
4 7xkd:R 261 206 0.2063 0.2261 0.2864 2.44e-12 7wui:R, 7xke:R, 7xkf:R
5 6nbh:R 379 274 0.2552 0.1926 0.2664 4.72e-10 8flt:R, 8ha0:R, 8haf:R, 8jr9:R, 6nbf:R, 6nbi:R
6 6pb1:P 281 271 0.2133 0.2171 0.2251 1.63e-09
7 7vvo:R 302 255 0.2343 0.2219 0.2627 4.29e-07 8gw8:R
8 4z9g:A 421 178 0.1643 0.1116 0.2640 1.58e-06 4k5y:A, 4k5y:B, 4z9g:B, 4z9g:C
9 4z9g:A 421 110 0.1119 0.0760 0.2909 0.22 4k5y:A, 4k5y:B, 4z9g:B, 4z9g:C
10 8e3y:R 372 268 0.2203 0.1694 0.2351 1.81e-06 8e3z:R, 6vn7:R
11 7d76:R 265 262 0.2238 0.2415 0.2443 1.91e-06 7d77:R
12 8e3x:R 362 231 0.1783 0.1409 0.2208 2.30e-05 6m1i:A, 6p9y:R
13 6lpb:R 331 232 0.1608 0.1390 0.1983 0.004
14 7knu:R 341 155 0.1503 0.1261 0.2774 0.090
15 7fin:R 380 152 0.1259 0.0947 0.2368 0.60 7dty:R, 7fiy:R, 7rbt:R, 7vab:R, 8yw4:R
16 3eo7:A 487 64 0.0664 0.0390 0.2969 1.1
17 8y52:R 299 104 0.0944 0.0903 0.2596 1.4 8y53:R
18 7psl:A 600 65 0.0769 0.0367 0.3385 2.8 4myh:B, 7psl:B, 7psm:A, 7psm:B, 7psn:A, 7psn:B
19 6fj3:A 562 64 0.0699 0.0356 0.3125 3.5 8d51:A, 8d52:A, 7uzo:A, 7uzp:A, 7uzp:C, 7uzp:E
20 6jko:A 376 47 0.0490 0.0372 0.2979 5.9 6jko:B, 6jko:C, 6jko:D, 6jkp:A, 6jkp:B, 6jkp:C, 6jkp:D
21 7cz5:R 269 278 0.2133 0.2268 0.2194 9.1 7v9m:R

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218