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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TRPNHTIYINNLNSKIKKDELKKSLHAIFSRFGQILDILVPRTRRPRGQAFVIFKEVSSATNALRSMQGFPFYDKPMAIQ
YAKTDRTI

The query sequence (length=88) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6xh2:A 93 88 0.9659 0.9140 0.9659 1.91e-59 6cmn:A, 3k0j:D, 3k0j:C, 6xh0:A, 6xh1:A, 6xh3:A
2 4pkd:B 240 88 0.8750 0.3208 0.8750 1.07e-50 1aud:A, 7b0y:c, 3bo2:A, 3bo3:A, 3bo4:A, 4c4w:A, 4c4w:E, 3cul:A, 3cul:B, 3cun:A, 3cun:B, 7d7v:C, 5ddo:G, 5ddo:C, 5ddp:D, 5ddp:C, 5ddq:D, 5ddq:C, 5ddr:D, 5ddr:C, 7dlz:A, 7dlz:B, 1drz:A, 7dwh:A, 7dwh:B, 1dz5:A, 1dz5:B, 3egz:A, 5fj4:A, 5fj4:E, 3g8s:A, 3g8s:B, 3g8s:C, 3g8s:D, 3g8t:A, 3g8t:B, 3g8t:C, 3g8t:D, 3g96:A, 3g96:B, 3g96:C, 3g96:D, 3g9c:A, 3g9c:B, 3g9c:C, 3g9c:D, 8gxb:C, 8gxb:D, 8gxb:F, 8gxc:C, 8gxc:D, 8gxc:F, 3hhn:B, 3hhn:D, 3iin:A, 3irw:P, 3iwn:C, 3iwn:D, 8jy0:A, 8jy0:C, 8jy0:E, 3k0j:A, 3k0j:B, 3l3c:A, 3l3c:B, 3l3c:C, 3l3c:D, 6las:E, 6las:D, 6las:C, 6lau:E, 6lau:D, 6lau:C, 6lax:D, 6lax:E, 6lax:C, 6laz:D, 6laz:E, 6laz:C, 1m5k:C, 1m5k:F, 1m5o:C, 1m5o:F, 1m5p:C, 1m5p:F, 1m5v:C, 1m5v:F, 3mum:P, 3mur:P, 3mut:P, 3muv:P, 3mxh:P, 2nz4:A, 2nz4:B, 2nz4:C, 2nz4:D, 2oih:A, 2oj3:A, 3p49:B, 4pr6:A, 4prf:A, 7qr3:A, 7qr3:B, 7qr4:A, 6qx9:1A, 3r1h:A, 3r1h:D, 3r1l:A, 3r1l:D, 1sj3:P, 1sj4:P, 1sjf:A, 6sqn:A, 6sqn:B, 6sqn:C, 6sqq:AAA, 6sqq:BBB, 6sqq:CCC, 1u6b:A, 3ucu:P, 3ucz:P, 3ud3:P, 3ud4:P, 1urn:A, 1urn:B, 1urn:C, 1vbx:A, 1vby:A, 1vbz:A, 1vc0:A, 1vc5:A, 1vc6:A, 7vpx:M, 4w90:B, 4w92:B, 1zzn:A
3 7abg:B 169 87 0.6932 0.3609 0.7011 3.65e-42 7a5p:X, 1a9n:B, 1a9n:D, 7abi:B, 6ah0:p, 6ahd:p, 8c6j:Y, 8ch6:s, 7evo:G, 9fmd:p, 8h6e:2C, 8h6j:2C, 8h6k:2C, 8h6l:2C, 8hk1:G, 8i0p:p, 8i0r:p, 8i0s:p, 8i0t:p, 8i0u:p, 8i0v:p, 8i0w:p, 6icz:p, 6id0:p, 6id1:p, 5mqf:X, 6qdv:Y, 8qo9:2B, 6qx9:2B, 8qxd:2B, 8qzs:2B, 8r08:2B, 8r09:2B, 8r0a:2B, 8r0b:2B, 8rm5:2B, 7vpx:G, 7w59:p, 7w5a:p, 7w5b:p, 5xjc:p, 6y53:b, 6y5q:b, 5yzg:p, 5z56:p, 5z57:p, 5z58:p
4 6f4h:C 96 86 0.7273 0.6667 0.7442 1.51e-37 6f4g:B, 6f4g:E, 6f4h:A, 6f4h:E
5 8ro1:p 76 76 0.5568 0.6447 0.6447 1.48e-35
6 3jb9:k 89 83 0.3977 0.3933 0.4217 4.82e-21
7 7b9v:Y 88 85 0.2955 0.2955 0.3059 3.52e-13 6bk8:r, 7dco:p, 6exn:Y, 6g90:Y, 5gmk:a, 6j6g:a, 6j6h:a, 6j6n:a, 6j6q:a, 5lj3:Y, 5lj5:Y, 5mq0:Y, 5nrl:Y, 7oqb:Y, 7oqe:Y, 5wsg:X, 5y88:p, 5ylz:p, 5zwm:p, 5zwo:p
8 3lqv:B 115 84 0.2955 0.2261 0.3095 3.89e-09 2f9j:B, 3lqv:A, 7q4o:F, 8qo9:B6, 8qxd:B6, 8qzs:B6, 8r08:B6, 8r09:B6, 8r0a:B6, 8r0b:B6, 8rm5:B6
9 2mb0:B 95 84 0.2955 0.2737 0.3095 1.23e-08
10 2fy1:A 108 79 0.2841 0.2315 0.3165 2.19e-07
11 2leb:A 101 84 0.2614 0.2277 0.2738 2.74e-07 2lec:A
12 7q33:A 93 84 0.2955 0.2796 0.3095 3.68e-07 6pai:D, 6q0r:D, 6q0v:D, 6q0w:D, 6sj7:C, 6ud7:C, 6ue5:C
13 7s7b:C 79 80 0.2386 0.2658 0.2625 2.11e-06 7s7b:G, 7s7c:C
14 7zew:A 117 81 0.2841 0.2137 0.3086 6.15e-06 7zex:A
15 8i0v:4 161 80 0.2841 0.1553 0.3125 2.07e-05
16 5mqf:o 223 82 0.2727 0.1076 0.2927 5.95e-05 6id1:y, 7w59:y, 7w5a:y, 7w5b:y
17 2x1f:A 94 84 0.2045 0.1915 0.2143 1.21e-04 2km8:B, 2x1a:A
18 2rra:A 99 68 0.2273 0.2020 0.2941 1.23e-04 2kxn:B
19 4ed5:B 169 66 0.2614 0.1361 0.3485 3.81e-04 4ed5:A
20 7qde:B 169 65 0.2273 0.1183 0.3077 4.22e-04 7qdd:B
21 2i2y:A 150 63 0.2273 0.1333 0.3175 4.56e-04 9asq:H, 5bmg:A, 5bmg:B, 5bmg:H, 5bmg:D, 5bmg:E, 5bmg:F, 5bmg:G, 5bmh:A, 3v3x:C, 3v3x:D
22 8y6o:W 167 89 0.2955 0.1557 0.2921 5.88e-04
23 6hpj:B 84 66 0.2273 0.2381 0.3030 7.11e-04
24 4f02:A 175 86 0.3068 0.1543 0.3140 0.001 1cvj:A, 1cvj:B, 1cvj:C, 1cvj:D, 1cvj:E, 1cvj:F, 1cvj:G, 1cvj:H, 4f02:D
25 8xxm:3G 84 83 0.2500 0.2619 0.2651 0.001 5k0y:O, 8pj1:o, 8pj2:o, 8pj3:o, 8pj4:o, 8pj5:o, 8pj6:o
26 7csz:A 175 44 0.2273 0.1143 0.4545 0.002
27 2n7c:A 89 74 0.2045 0.2022 0.2432 0.002
28 6dg0:B 84 80 0.2614 0.2738 0.2875 0.003 6dg0:A
29 8h6e:4R 106 77 0.2614 0.2170 0.2987 0.004 8h6j:4R, 8qp8:R, 8qp9:R, 8qpk:R, 6qw6:R, 6qx9:R, 8qxd:R, 8r08:R, 8r0a:R
30 6g90:B 193 70 0.2500 0.1140 0.3143 0.004
31 5ith:A 80 70 0.2500 0.2750 0.3143 0.004 5o3j:A
32 6n7p:A 186 70 0.2500 0.1183 0.3143 0.005 6n7r:A, 6n7x:A, 7oqc:B, 7oqe:B, 8w2o:A, 5zwn:Q
33 4qqb:A 169 64 0.2386 0.1243 0.3281 0.006 1b7f:A, 1b7f:B, 4qqb:B
34 4qqb:A 169 71 0.2045 0.1065 0.2535 1.5 1b7f:A, 1b7f:B, 4qqb:B
35 2yka:A 124 76 0.2273 0.1613 0.2632 0.007
36 4a8x:A 88 67 0.2386 0.2386 0.3134 0.007
37 2mgz:B 105 46 0.1932 0.1619 0.3696 0.010 4ch1:A, 4cio:A, 2ru3:A
38 8xxn:3B 536 53 0.1705 0.0280 0.2830 0.012 6zon:B, 6zp4:B, 6zvj:B
39 8pj1:1 588 53 0.1705 0.0255 0.2830 0.017 6fec:w, 2krb:A, 8oz0:I, 8pj2:1, 8pj3:1, 8pj5:1, 8pj6:1
40 4lmz:A 176 81 0.2500 0.1250 0.2716 0.017 3nmr:A, 3nna:A, 3nnc:A, 3nnh:A, 3nnh:C, 3nnh:B, 3nnh:D
41 1fje:B 175 81 0.2614 0.1314 0.2840 0.021 1rkj:A
42 2adb:A 127 50 0.2045 0.1417 0.3600 0.048 3zzy:A, 3zzy:B, 3zzz:A, 3zzz:B
43 2n82:B 104 46 0.1705 0.1442 0.3261 0.048 2err:A, 7vrl:B
44 7zap:A 97 88 0.2500 0.2268 0.2500 0.054
45 7evo:D 200 62 0.2045 0.0900 0.2903 0.072 8hk1:D, 6n3e:A, 6n3f:C, 6nsx:A
46 2mxy:A 105 79 0.2614 0.2190 0.2911 0.077 2mz1:A
47 4bs2:A 174 50 0.1477 0.0747 0.2600 0.12 4iuf:A, 4y00:A, 4y00:B, 4y00:C, 4y00:D, 4y0f:A, 4y0f:B
48 8esq:o 137 69 0.1818 0.1168 0.2319 0.36 8esr:o, 8etg:o, 8eth:o, 8eti:o, 8eup:o, 8euy:o, 8ev3:o
49 3s1s:A 870 52 0.1818 0.0184 0.3077 0.40
50 3d2w:A 72 43 0.1250 0.1528 0.2558 0.41
51 8pv1:CI 152 68 0.2273 0.1316 0.2941 0.52 8i9p:CI, 8i9r:CI, 8i9t:CI, 8i9v:CI, 8i9w:CI, 8i9x:CI, 8i9y:CI, 8i9z:CI, 8ia0:CI, 8pv3:CI, 8pv4:CI, 8pv7:CI, 8pvk:CI
52 2mki:A 203 64 0.2045 0.0887 0.2812 1.2
53 4uer:b 572 52 0.1705 0.0262 0.2885 1.8
54 6gsn:p 658 52 0.1705 0.0228 0.2885 2.1 8cah:p, 8cas:p, 6fyx:p, 6fyy:p, 6gsm:p, 6zce:p, 6zu9:p
55 7vki:A 113 21 0.1364 0.1062 0.5714 2.5
56 3cei:A 213 29 0.1477 0.0610 0.4483 2.9 3cei:B
57 8vlx:A 2431 35 0.1364 0.0049 0.3429 3.5
58 3d34:B 215 22 0.1023 0.0419 0.4091 3.6 3d34:A
59 6qx9:1K 201 64 0.1364 0.0597 0.1875 4.0 7b0y:b, 4pjo:K, 4pjo:k, 4pjo:N, 4pjo:n, 8r08:1K, 7vpx:O
60 1u08:A 382 45 0.1591 0.0366 0.3111 4.2 1u08:B
61 8z9x:B 567 15 0.1250 0.0194 0.7333 4.3 8z9x:A
62 8z0f:A 549 15 0.1250 0.0200 0.7333 4.4 8z0f:B
63 7r7j:B 574 50 0.1705 0.0261 0.3000 4.5 8h5y:B, 8h5y:A, 8h5z:B, 8h5z:A, 6jde:B, 6jde:A, 7r7j:A
64 1r8d:A 109 38 0.1250 0.1009 0.2895 4.6 1r8d:B
65 6bbp:A 520 42 0.1818 0.0308 0.3810 5.1 2a5d:A, 2a5f:A, 2a5g:A, 6bbq:A, 1e0s:A, 1fgy:A, 1fhw:A, 1fhw:B, 1fhx:A, 1fhx:B, 4fme:C, 4fme:F, 2j5x:A, 2j5x:B, 4kax:A, 4kax:B, 3n5c:A, 3n5c:B, 3pcr:B, 2r09:A, 2r09:B, 2r0d:A, 2r0d:B, 3vhx:A, 3vhx:C, 3vhx:E, 3vhx:G, 2w83:A, 2w83:B, 2w83:E, 7xrd:A, 7xrd:B, 7xrd:C, 7xrd:D
66 7un8:A 297 54 0.1591 0.0471 0.2593 5.4 7un8:B, 7un8:C, 7un8:D, 7un8:E, 7un8:F, 7un9:A, 7un9:B, 7un9:C, 7un9:D, 7un9:I, 7un9:J, 7un9:E, 7un9:F, 7un9:K, 7un9:L, 7una:A, 7una:B, 7una:C
67 3m1c:A 719 42 0.1705 0.0209 0.3571 7.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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