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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TLSITSNFDAGAIDVVSCDSPDAIRLRVRGDNRSEFAQWFYYRLTGARGERCVMTFENAAECAYPSGWRNYSAVASYDRV
DWFRVPTTFDGKTMTIDHTPEFDSIYYAYFEPYSEERHAAFLGAVQQLPQASVVELGRTVEGRPMSLLTLGTPETAPKKK
VWIIARQHPGESMAEWFVEGLVKRLAGWGDWAGDPVARKLYDRVTFHIVPNMNPDGSVHGNLRTNAAGANLNREWMAPDA
ERSPEVLAVRDAIHAIGCDMFFDIHGDEDLPYVFVAGSEMLPSFTEQQGKEQTAFIEAFKVASPDFQTEHGYAASKYKED
ALKLASKYIGHQFGCLSLTLEMPFKDNANLPDERVGWNGERSAALGAAMLAAILVHVDTF

The query sequence (length=380) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4b6z:B 382 382 0.9974 0.9921 0.9921 0.0 4b6z:A, 4b6z:C, 4b6z:D
2 3l2n:A 376 377 0.4684 0.4734 0.4721 9.90e-124 3l2n:B
3 4a37:B 376 381 0.4211 0.4255 0.4199 3.60e-104 4a37:A, 4a38:A, 4a38:B, 4a39:A, 4a39:B
4 8v3o:A 471 179 0.1263 0.1019 0.2682 9.30e-13 8v3p:A
5 8v3q:A 501 178 0.1211 0.0918 0.2584 7.09e-12 8v3m:A, 8v3n:A, 8v3r:A, 8v3s:A, 8v4k:E, 8v4l:E, 8v4m:E
6 2boa:A 404 176 0.1158 0.1089 0.2500 1.05e-05 4a94:A, 4a94:B, 4bd9:A, 2bo9:A, 2bo9:C, 2boa:B, 2pcu:A
7 3mn8:B 386 172 0.1289 0.1269 0.2849 1.84e-05 3mn8:A, 3mn8:C, 3mn8:D
8 5mrv:A 307 84 0.0658 0.0814 0.2976 2.82e-05 5mrv:B
9 1uwy:A 393 180 0.1316 0.1272 0.2778 2.13e-04
10 1aye:A 401 135 0.0921 0.0873 0.2593 6.43e-04 1dtd:A
11 1h8l:A 380 148 0.0974 0.0974 0.2500 0.010 1qmu:A
12 1pyt:B 309 214 0.1368 0.1683 0.2430 0.014 2abz:A, 2abz:B, 1arm:A, 1bav:A, 1bav:B, 1bav:C, 1bav:D, 1cbx:A, 1cps:A, 1cpx:A, 3cpa:A, 4cpa:A, 4cpa:B, 5cpa:A, 6cpa:A, 7cpa:A, 8cpa:A, 2ctb:A, 2ctc:A, 1ee3:P, 1ell:P, 1elm:P, 1f57:A, 3fvl:A, 3fvl:C, 3fvl:E, 3fx6:A, 3fx6:C, 3fx6:E, 1hdq:A, 1hdu:A, 1hdu:B, 1hdu:D, 1hdu:E, 1hee:A, 1hee:B, 1hee:D, 1hee:E, 3hlp:A, 3hlp:B, 3huv:A, 3i1u:A, 1iy7:A, 3kgq:A, 1m4l:A, 2rfh:A, 1yme:A, 1zlh:A
13 1jqg:A 409 222 0.1474 0.1369 0.2523 0.11
14 5om9:A 396 118 0.0711 0.0682 0.2288 0.40 3fju:A, 6i6z:A, 6i6z:B, 5om9:B, 4uee:A, 4uee:B, 4uez:A, 4uez:B, 2v77:A, 2v77:B
15 2yev:B 319 144 0.0974 0.1160 0.2569 0.82 2yev:E
16 5hxd:A 237 31 0.0421 0.0675 0.5161 1.9 5hxd:B
17 3ild:A 148 50 0.0447 0.1149 0.3400 2.5
18 1r5o:A 409 32 0.0342 0.0318 0.4062 3.6 1r5n:A
19 3ieh:A 268 76 0.0605 0.0858 0.3026 5.3
20 6ut3:B 365 99 0.0711 0.0740 0.2727 5.9
21 6ut5:A 395 99 0.0711 0.0684 0.2727 6.5 6ut3:C, 6ut3:D, 6ut3:E, 6ut3:F, 6ut4:A, 6ut4:B, 6ut4:C, 6ut4:D, 6ut4:E, 6ut4:F, 6ut5:B, 6ut5:C, 6ut5:D, 6ut5:E, 6ut5:F, 6ut7:A, 6ut7:B, 6ut7:C, 6ut7:D, 6ut7:E, 6ut7:F, 6ut7:H, 6ut7:I, 6ut7:J, 6ut7:K, 6ut7:L, 6ut7:M, 6ut8:A, 6ut8:B, 6ut8:C, 6ut8:D, 6ut8:E, 6ut8:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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