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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TEFDEATVQDVVRLAGGHDSELRELTQKYDPAMISRLLVAEILSRCPPPSNDTPVLVELAIVHGSERFRHFLRVVRDSPI
RPVGADEGFVGMLVEYELTELLRELFGVTHERPAGVRGTKLFPYLTDDEEAVEQIGTYLLAAQQGTEAVLAGCGSRKPDL
SELSSRYFTPKFGFLHWFTPHYDRHFRDYRNQQVRVLEIGVGGYKHPEWGGGSLRMWKSFFPRGQIYGLDIMDKSHVDEL
RIRTIQGDQNDAEFLDRIARRYGPFDIVIDDGSHINAHVRTSFAALFPHVRPGGLYVIEDMWTAYWPGFGGQADPQECSG
TSLGLLKSLIDAIQHQELPSDPNRSPGYVDRNIVGLHVYHNVAFVEKGRNDEGGIPTWIPRDFESLVQASSGG

The query sequence (length=393) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3sso:B 394 392 0.9975 0.9949 1.0000 0.0 3ssm:A, 3ssm:C, 3ssm:D, 3ssn:A, 3ssn:D, 3ssn:C, 3sso:A, 3sso:C, 3sso:D, 3sso:E, 3sso:F
2 3ssn:B 350 391 0.8906 1.0000 0.8951 0.0
3 8iaa:B 383 381 0.4351 0.4465 0.4488 3.08e-104 8ia9:A, 8ia9:B, 8iaa:A
4 3a5z:C 324 41 0.0382 0.0463 0.3659 0.24 3a5y:B, 3a5y:C, 3a5y:D, 3a5z:A, 3a5z:E, 3a5z:G, 3g1z:A, 3g1z:B
5 3a5y:A 297 41 0.0382 0.0505 0.3659 0.26
6 8hkx:AS2P 196 37 0.0382 0.0765 0.4054 2.1 8hky:AS2P, 8hkz:AS2P, 8hl1:AS2P, 8hl2:AS2P, 8hl3:AS2P, 8hl4:AS2P, 8hl5:AS2P, 8wkp:AS2P, 8wq2:AS2P, 8wq4:AS2P
7 8ila:A 429 55 0.0483 0.0443 0.3455 2.3 8ila:C, 8ila:B, 8ila:D, 8ixq:B, 8ixq:D
8 2gpy:B 192 122 0.0840 0.1719 0.2705 3.4 2gpy:A
9 6uk5:A 240 122 0.0763 0.1250 0.2459 4.8 6uk5:B
10 1a7a:A 431 47 0.0331 0.0302 0.2766 6.5 1a7a:B, 5axa:A, 5axa:C, 5axb:A, 5axb:C, 5axc:A, 5axc:C, 5axd:A, 5axd:C, 1b3r:A, 1b3r:B, 1b3r:C, 1b3r:D, 8cod:A, 8cod:B, 1d4f:A, 1d4f:B, 1d4f:C, 1d4f:D, 2h5l:A, 2h5l:B, 2h5l:C, 2h5l:D, 2h5l:E, 2h5l:F, 2h5l:G, 2h5l:H, 1k0u:A, 1k0u:B, 1k0u:C, 1k0u:D, 1k0u:E, 1k0u:F, 1k0u:G, 1k0u:H, 1ky4:A, 1ky4:B, 1ky4:C, 1ky4:D, 1ky5:A, 1ky5:B, 1ky5:C, 1ky5:D, 1li4:A, 3nj4:A, 3nj4:B, 3nj4:C, 3nj4:D, 4pfj:A, 4pfj:B, 4pgf:A, 4pgf:B, 5w49:A, 5w49:B, 5w4b:A, 5w4b:B, 5w4b:C, 5w4b:D, 5w4b:E, 5w4b:F, 1xwf:A, 1xwf:B, 1xwf:C, 1xwf:D, 4yvf:A, 4yvf:B
11 1j5p:A 235 31 0.0356 0.0596 0.4516 7.0 1h2h:A
12 4gnk:B 769 50 0.0458 0.0234 0.3600 7.3 8emv:A, 8emw:A, 8emx:A, 4gnk:D, 4qj3:B, 4qj4:B, 4qj5:B, 7sq2:B, 8uqn:B, 8uqo:Q
13 7plb:B 289 156 0.1069 0.1453 0.2692 8.5 7plb:A, 7plc:A, 7plc:D, 7plc:B, 7plc:C, 7pld:A, 7pld:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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