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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TDKERFIASLMARMSNAEKIGQLRLVSVGADHPKEALMADIRAGKVGAIFNTVTRPDIRAMQDQVRHSRLKIPLFHAYDV
AHGHRTIFPISLGLAASWDPEVVARSARISALEASADGLDMSFSPMVDITRDARWGRVSEGFGEDTYLTSLLSGVMVRAY
QGSNLAAPDSIMAAVKHFALYGAAEGGRDYNTVDMSLPRMFQDYLPPYKAAVDAGAGAVMVSLNTINGVPATANRWLLTD
LLRQQWGFKGLTISNHGAVKELIKHGLAGNERDATRLAIQAGVDMNMNDDLYSTWLPKLLAAGEIDQADIDRACRDVLAA
KYDLGLFADPYRRLGKPDDPPFDTNAESRLHRQAAREVAREGLVLLKNRDGLLPLKKQGRIAVIGPLAKSQRDVIGSWSA
AGVPRQAVTVYQGLANAVGERATLLYAKGANVSGDQAILDYLNSYNPEVEVDPRSAEAMLEEALRTARDADLVVAVVGES
QGMAHEASSRTDLRIPASQRRLLKALKATGKPLVLVLMNGRPLSLGWEQENADAILETWFSGTEGGNAIADVLFGEHNPS
GKLTMSFPRSVGQVPVYYNHLNTGRPMDHDNPGKYTSRYFDEANGPLYPFGYGLSYTEFSLSPLRLSSERLARGATLEAR
VTLSNSGKRAGATVVQLYLQDPVASLSRPVKELRGFRKVMLEPGESREIVFRLGEADLKFYDSQLRHTAEPGEFKVFVGL
DSAQTESRSFTLL

The query sequence (length=733) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6r5i:A 733 733 0.9986 0.9986 0.9986 0.0 6r5i:B, 6r5n:B, 6r5n:A, 6r5o:B, 6r5o:A, 6r5p:B, 6r5p:A, 6r5r:B, 6r5r:A, 6r5t:B, 6r5t:A, 6r5u:B, 6r5u:A, 6r5v:B, 6r5v:A
2 3u48:B 742 736 0.5075 0.5013 0.5054 0.0 3u48:A, 3u4a:B, 3u4a:A
3 5tf0:A 733 743 0.4898 0.4898 0.4832 0.0 5tf0:B
4 5xxm:A 749 749 0.4966 0.4860 0.4860 0.0 5xxl:A, 5xxl:B, 5xxm:B, 5xxn:A, 5xxn:B, 5xxo:B, 5xxo:A
5 4zo6:B 724 737 0.4147 0.4199 0.4125 0.0 4zo6:A, 4zo7:B, 4zo7:A, 4zo8:A, 4zo8:B, 4zo9:A, 4zo9:B, 4zoa:A, 4zoa:B, 4zob:A, 4zob:B, 4zoc:A, 4zoc:B, 4zod:A, 4zod:B, 4zoe:A, 4zoe:B
6 7zgz:X 753 671 0.3356 0.3267 0.3666 9.49e-138 8c7f:B
7 8c7f:A 772 691 0.3397 0.3225 0.3603 8.85e-135 7zb3:A, 7zb3:B, 7zdy:W, 7zdy:Y, 7zgz:Y
8 5z9s:A 765 781 0.3724 0.3569 0.3496 3.29e-133 5z9s:B
9 5z87:A 756 699 0.3452 0.3347 0.3619 5.06e-127 5z87:B
10 8xrt:F 751 752 0.3574 0.3489 0.3484 2.83e-113 8xrt:E, 8xrt:A, 8xrt:B, 8xrt:C, 8xrt:D, 8xru:A, 8xru:B, 8xrv:A, 8xrv:B, 8xrv:C, 8xrv:F, 8xrv:D, 8xrv:E, 8xrx:A, 8xrx:D, 8xrx:F, 8xrx:B, 8xrx:C
11 7eap:A 755 701 0.3151 0.3060 0.3295 4.32e-99 5yot:A, 5yot:B, 5yqs:A, 5yqs:B
12 5jp0:A 745 755 0.3206 0.3154 0.3113 3.80e-93 5jp0:B
13 8j9f:D 749 676 0.2920 0.2857 0.3166 1.33e-92 8j9f:A, 8j9f:B
14 5wab:A 674 667 0.2879 0.3131 0.3163 3.96e-81
15 5m6g:A 579 628 0.2851 0.3610 0.3328 9.69e-77
16 2x41:A 715 667 0.2606 0.2671 0.2864 2.34e-67 2x42:A
17 6jg1:A 606 644 0.2538 0.3069 0.2888 4.86e-56 1ex1:A, 1ieq:A, 1iev:A, 1iew:A, 1iex:A, 1j8v:A, 6jg2:A, 6jg6:A, 6jg7:A, 6jga:A, 6jgb:A, 6jgc:A, 6jgd:A, 6jge:A, 6jgg:A, 6jgk:A, 6jgl:A, 6jgn:A, 6jgo:A, 6jgp:A, 6jgq:A, 6jgr:A, 6jgs:A, 6jgt:A, 6k6v:A, 6kuf:A, 6l1j:A, 6lbb:A, 6lbv:A, 6lc5:A, 1lq2:A, 6md6:A, 6mi1:A, 3wlh:A, 3wlj:A, 3wlk:X, 3wll:A, 3wlo:A, 3wlp:A, 1x38:A, 1x39:A
18 3ut0:A 804 576 0.2333 0.2127 0.2969 5.32e-54 3rrx:A, 3usz:A, 3ut0:B, 3ut0:C, 3ut0:D
19 6jxg:A 713 677 0.2647 0.2721 0.2866 2.84e-50
20 4i8d:B 714 700 0.2524 0.2591 0.2643 1.14e-47 4i8d:A, 3zyz:A
21 6q7i:A 770 703 0.2592 0.2468 0.2703 3.84e-46 6q7j:A, 6q7j:B
22 7vc7:A 743 691 0.2633 0.2598 0.2793 1.10e-43
23 8xrx:E 611 192 0.1091 0.1309 0.4167 3.19e-43
24 8xrx:E 611 399 0.1828 0.2193 0.3358 4.11e-38
25 5ae6:B 767 679 0.2565 0.2451 0.2769 8.04e-41 5a7m:A, 5a7m:B, 5ae6:A
26 3ac0:A 841 269 0.1214 0.1058 0.3309 9.99e-34 3ac0:B, 3ac0:C, 3ac0:D
27 3ac0:A 841 376 0.1419 0.1237 0.2766 3.44e-29 3ac0:B, 3ac0:C, 3ac0:D
28 7xtj:B 743 686 0.2538 0.2503 0.2711 1.32e-33 7xtj:A
29 4iib:A 834 586 0.1992 0.1751 0.2491 2.87e-33 4iib:B, 4iic:A, 4iic:B, 4iid:A, 4iid:B, 4iie:A, 4iie:B, 4iif:A, 4iif:B, 4iig:A, 4iig:B, 4iih:A, 4iih:B
30 4iib:A 834 91 0.0396 0.0348 0.3187 0.23 4iib:B, 4iic:A, 4iic:B, 4iid:A, 4iid:B, 4iie:A, 4iie:B, 4iif:A, 4iif:B, 4iig:A, 4iig:B, 4iih:A, 4iih:B
31 5fji:A 840 587 0.2142 0.1869 0.2675 2.40e-32 5fji:B
32 5fji:A 840 63 0.0286 0.0250 0.3333 0.040 5fji:B
33 5fjj:A 839 621 0.2265 0.1979 0.2673 6.62e-32 5fjj:B, 5fjj:C, 5fjj:D
34 6jbs:A 762 725 0.2428 0.2336 0.2455 3.74e-31 7ey1:B, 7ey1:A, 7ey2:A, 7ey2:B, 7ey2:C, 7ey2:D, 7ey2:E, 7ey2:F, 7f95:A, 7f95:B, 8gyy:B, 8gyy:A, 8gyy:C, 8gyy:D, 6jbs:C, 6jbs:D, 6kj0:A, 6kj0:B, 7yo6:A, 7yo6:B, 7yo7:B, 7yo7:A
35 4i3g:B 780 266 0.1255 0.1179 0.3459 1.51e-29 4i3g:A
36 4i3g:B 780 492 0.1842 0.1731 0.2744 1.79e-26 4i3g:A
37 5ju6:A 835 585 0.1992 0.1749 0.2496 5.10e-29 5ju6:B, 5ju6:C, 5ju6:D
38 5ju6:A 835 69 0.0355 0.0311 0.3768 0.10 5ju6:B, 5ju6:C, 5ju6:D
39 5nbs:A 842 594 0.2156 0.1876 0.2660 1.03e-28 5nbs:B
40 5nbs:A 842 82 0.0368 0.0321 0.3293 0.058 5nbs:B
41 5k6o:A 795 406 0.1583 0.1459 0.2857 3.48e-26 5k6m:A, 5k6n:A
42 5k6o:A 795 285 0.1023 0.0943 0.2632 6.28e-13 5k6m:A, 5k6n:A
43 6sz6:A 836 600 0.2101 0.1842 0.2567 6.23e-26
44 5wvp:A 924 398 0.1446 0.1147 0.2663 2.30e-22
45 5wvp:A 924 207 0.0832 0.0660 0.2947 4.41e-14
46 7qg4:A 746 399 0.1501 0.1475 0.2757 9.59e-21 7qe1:A, 7qe1:B, 7qe2:A, 7qe2:B, 7qea:A, 7qea:B, 7qee:A, 7qee:B, 7qef:A, 7qef:B, 7qg4:B
47 7qg4:A 746 72 0.0327 0.0322 0.3333 0.057 7qe1:A, 7qe1:B, 7qe2:A, 7qe2:B, 7qea:A, 7qea:B, 7qee:A, 7qee:B, 7qef:A, 7qef:B, 7qg4:B
48 4gyj:A 618 432 0.1405 0.1667 0.2384 1.15e-19 3bmx:A, 3bmx:B, 4gyj:B, 4gyk:A, 3nvd:A, 3nvd:B
49 5c0q:B 457 264 0.0859 0.1379 0.2386 1.98e-11 5c0q:A, 5c0q:C, 5c0q:D
50 6k5j:A 526 342 0.1132 0.1578 0.2427 1.86e-10
51 4zm6:A 844 395 0.1228 0.1066 0.2278 2.32e-09 4zm6:B
52 5vqe:A 559 433 0.1282 0.1682 0.2171 1.75e-08
53 6jtk:B 346 191 0.0696 0.1474 0.2670 1.24e-05 6jtk:A, 6jtk:C, 6jtk:F, 6jtk:D, 6jtk:E
54 2oxn:A 333 191 0.0641 0.1411 0.2461 1.55e-05 3gs6:A, 3gsm:A
55 5g3r:A 335 192 0.0668 0.1463 0.2552 7.60e-05 5g3r:B, 5g5k:A, 5g5k:B, 5g6t:A, 5g6t:B, 5ly7:A, 5ly7:B
56 6dte:B 340 217 0.0750 0.1618 0.2535 2.25e-04 6dte:A, 4mss:A, 4mss:B, 5utp:A, 5utp:B, 5utq:A, 5utq:B, 5utr:A, 5utr:B
57 7vi6:A 342 246 0.0778 0.1667 0.2317 0.060 7vi6:B, 7vi7:A, 7vi7:B
58 1mky:A 407 98 0.0409 0.0737 0.3061 0.11
59 4gvh:A 341 193 0.0668 0.1437 0.2539 0.30 4gvh:B, 4gvi:B, 4hzm:A, 4hzm:B
60 8qhe:A 284 135 0.0464 0.1197 0.2519 0.84 6sle:A, 6sle:C, 6sle:H, 6sle:D, 6sle:E, 6sle:F, 6sle:G
61 3b95:B 225 104 0.0382 0.1244 0.2692 1.7
62 6v98:A 183 94 0.0382 0.1530 0.2979 9.6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218