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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNK
LYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPF
YTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKH
ALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKMREFTKTIK

The query sequence (length=291) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3e2t:A 307 291 0.9210 0.8730 0.9210 0.0 8cji:A, 8cjj:A, 8cjk:A, 8cjl:A, 8cjm:A, 8cjn:A, 8cjo:A, 3hf6:A, 3hf8:A, 3hfb:A, 5j6d:A, 5l01:A, 1mlw:A, 7zif:A, 7zig:A, 7zih:A, 7zii:A, 7zij:A, 7zik:A, 7zik:B
2 5tpg:A 271 291 0.9278 0.9963 0.9278 0.0
3 4v06:A 349 289 0.8213 0.6848 0.8270 0.0 4v06:B, 7wiy:B, 7wiy:C, 7wiy:D, 7wiy:A
4 5j6d:B 248 288 0.8419 0.9879 0.8507 3.50e-168
5 5fgj:A 428 290 0.6529 0.4439 0.6552 7.93e-139 4anp:A, 5den:A, 5den:B, 5den:C, 5den:D, 1dmw:A, 5fgj:B, 5fgj:C, 5fgj:D, 6hpo:A, 6hyc:D, 6hyc:C, 6hyc:B, 1j8t:A, 1j8u:A, 1kw0:A, 1lrm:A, 1mmk:A, 1mmt:A, 6n1k:A, 6n1k:B, 6n1k:C, 6n1k:D, 1pah:A, 2pah:A, 2pah:B, 3pah:A, 4pah:A, 5pah:A, 6pah:A, 1phz:A, 2phm:A, 1tdw:A, 1tg2:A
6 6zvp:D 458 290 0.6151 0.3908 0.6172 4.97e-136 7a2g:A, 7a2g:B, 7a2g:C, 7a2g:D, 7pim:B, 7pim:A, 7pim:D, 7pim:F, 1toh:A, 2toh:A, 2xsn:A, 2xsn:B, 2xsn:C, 2xsn:D, 6zn2:A, 6zn2:C, 6zn2:E, 6zn2:G, 6zvp:A, 6zvp:B, 6zvp:C, 6zzu:B, 6zzu:A, 6zzu:C, 6zzu:D
7 5jk5:A 400 290 0.6186 0.4500 0.6207 1.50e-135 5jk5:B, 5jk6:A, 5jk6:B, 5jk8:A, 5jk8:B
8 4etl:A 277 223 0.2749 0.2888 0.3587 7.00e-34 4esm:A, 4jpx:A, 4jpy:A, 1ltv:A, 1ltz:A, 4q3w:A, 4q3x:A, 4q3y:A, 4q3z:A, 3tcy:A, 3tk2:A, 3tk4:A
9 2v27:B 272 227 0.2577 0.2757 0.3304 1.02e-31 2v27:A
10 7vgm:A 571 235 0.1959 0.0998 0.2426 1.49e-16
11 2csh:A 110 62 0.0687 0.1818 0.3226 0.47
12 8sny:A 1388 76 0.0722 0.0151 0.2763 0.76 8fu3:A, 8snx:A
13 8fpi:A 1357 76 0.0722 0.0155 0.2763 0.76
14 5b46:A 627 45 0.0550 0.0255 0.3556 1.7 5b47:A
15 5hvf:A 372 199 0.1443 0.1129 0.2111 2.2
16 4p10:A 402 200 0.1443 0.1045 0.2100 2.6 3d66:A, 3d66:B, 3d66:C, 3d67:A, 3d67:B, 3d67:C, 3d68:A, 3d68:B, 3d68:C, 5hvg:A, 5hvg:C, 5hvh:A, 3lms:A, 7nee:A, 7neu:A
17 6n9a:D 330 39 0.0550 0.0485 0.4103 3.6 6nak:B, 6nak:G, 6s84:A, 6s84:D
18 8dd5:A 272 73 0.0756 0.0809 0.3014 3.6 1m36:A, 2ozu:A, 2rc4:A
19 4a4a:A 886 88 0.0825 0.0271 0.2727 3.7 7mfk:A, 7mfl:A, 2vc9:A, 2vca:A, 2vcb:A, 2vcc:A
20 7nhk:F 132 45 0.0481 0.1061 0.3111 3.9
21 6om8:D 468 41 0.0515 0.0321 0.3659 4.4 6om8:A, 6om8:B, 6om8:C, 6om8:E, 6om8:F, 6om8:G, 6om8:H, 6om8:I, 6om8:J, 6om8:K, 6om8:L
22 7p7q:F 226 45 0.0481 0.0619 0.3111 4.6 7p7r:F, 7p7s:F, 7p7t:F
23 3dwc:B 504 112 0.1134 0.0655 0.2946 5.4 3dwc:A, 3dwc:C, 3dwc:D
24 5z9x:A 288 139 0.1065 0.1076 0.2230 7.4
25 6xeo:A 1118 156 0.1375 0.0358 0.2564 9.5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218