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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SSYSGPIVVDPVTRIEGHLRIEVEVENGKVKNAYSSSTLFRGLEIILKGRDPRDAQHFTQRTCGVCTYTHALASTRCVDN
AVGVHIPKNATYIRNLVLGAQYLHDHIVHFYHLHALDFVDVTAALKADPAKAAKVASSISPRKTTAADLKAVQDKLKTFV
ETGQLGPFTNAYFLGGHPAYYLDPETNLIATAHYLEALRLQVKAARAMAVFGAKNPHTQFTVVGGVTCYDALTPQRIAEF
EALWKETKAFVDEVYIPDLLVVAAAYKDWTQYGGTDNFITFGEFPKDEYDLNSRFFKPGVVFKRDFKNIKPFDKMQIEEH
VRHSWYEGAEARHPWKGQTQPKYTDLHGDDRYSWMKAPRYMGEPMETGPLAQVLIAYSQGHPKVKAVTDAVLAKLGVGPE
ALFSTLGRTAARGIETAVIAEYVGVMLQEYKDNIAKGDNVICAPWEMPKQAEGVGFVNAPRGGLSHWIRIEDGKIGNFQL
VVPSTWTLGPRCDKNNVSPVEASLIGTPVADAKRPVEILRTVHSFDPCIACGVH

The query sequence (length=534) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1h2a:L 534 534 1.0000 1.0000 1.0000 0.0 1h2r:L, 4u9h:L, 4u9i:L, 1ubh:L, 1ubj:L, 1ubk:L, 1ubl:L, 1ubm:L, 1ubo:L, 1ubr:L, 1ubt:L, 1ubu:L, 8w6x:L, 1wuh:L, 1wui:L, 1wuj:L, 1wuk:L, 1wul:L, 5xle:L, 5xlf:L, 5xlg:L, 5xlh:L, 5y4n:L
2 1e3d:B 537 536 0.6854 0.6816 0.6828 0.0 1e3d:D
3 1frv:B 530 529 0.6816 0.6868 0.6881 0.0 1frv:D, 2frv:L, 2frv:B, 2frv:D, 2frv:F, 2frv:H, 2frv:J, 1yq9:H, 1yq9:I
4 3cur:H 545 541 0.6610 0.6477 0.6525 0.0 3cur:I, 3cur:J, 3cus:Q, 3cus:R, 3cus:S, 1frf:L, 3h3x:Q, 3h3x:R, 3h3x:S, 4ucq:Q, 4ucq:R, 4ucq:S, 4ucw:Q, 4ucw:R, 4ucw:S, 4ucx:Q, 4ucx:R, 4ucx:S, 4ud2:S, 4ud2:Q, 4ud2:R, 4ud6:Q, 4ud6:R, 4ud6:S, 4ue2:Q, 4ue2:R, 4ue2:S, 4ue6:R, 4ue6:Q, 4ue6:S, 4ueq:Q, 4ueq:R, 4ueq:S, 4ueq:T, 4ueq:U, 4ueq:V, 4uew:Q, 4uew:R, 4uew:S, 4upe:Q, 4upe:R, 4upe:S, 4upv:Q, 4upv:R, 4uql:Q, 4uql:R, 4uqp:Q, 4uqp:R, 4urh:Q, 4urh:S, 4urh:R, 1yqw:Q, 1yqw:R, 1yqw:S, 1yrq:H, 1yrq:I, 1yrq:J, 1yrq:K, 1yrq:M, 1yrq:N
5 3myr:D 561 560 0.4981 0.4742 0.4750 6.84e-178 3myr:B, 3myr:F, 3myr:H
6 4c3o:A 583 570 0.4775 0.4374 0.4474 5.38e-169 4c3o:C, 4c3o:E
7 6ehq:L 551 551 0.4476 0.4338 0.4338 4.75e-155 6ehq:M, 6ehs:L, 6ehs:M, 6en9:L, 6en9:M, 6g7m:L, 6g7m:M, 6gam:L, 6gam:M, 6gan:L, 6gan:M, 7nem:L, 7nem:M, 6syo:LLL, 6syo:MMM, 6syx:LLL, 6syx:MMM, 6szd:LLL, 6szd:MMM, 6szk:LLL, 6szk:MMM, 7vxq:A, 7vxq:C, 5xvb:L, 5xvb:M, 5xvc:L, 5xvc:M, 5xvd:L, 5xvd:M
8 4iub:L 602 590 0.4682 0.4153 0.4237 1.39e-152 5d51:L, 4iuc:L, 4iud:L, 5mdj:L, 5mdk:L, 5mdl:L, 7odg:L, 7odh:L, 8pou:L, 8pov:L, 8pow:L, 8pox:L, 8poz:L, 3rgw:L, 4ttt:L
9 3ayx:A 595 585 0.4607 0.4134 0.4205 2.11e-151 3ayx:C, 3ayz:A, 3ayz:C, 5y34:A, 5y34:C
10 5a4f:L 581 567 0.4438 0.4079 0.4180 7.68e-146 5a4f:M, 5a4i:L, 5a4i:M, 5a4m:L, 5a4m:M, 5adu:L, 5adu:M, 6fpi:L, 6fpi:M, 6fpo:L, 6fpo:M, 6fpw:L, 6fpw:M, 6g7r:L, 6g7r:M, 6g94:L, 6g94:M, 6g94:J, 6g94:K, 6gal:L, 6gal:M, 4gd3:L, 4gd3:M, 4gd3:J, 4gd3:K, 5jrd:L, 5jrd:M, 5lmm:L, 5lmm:M, 5lry:L, 5lry:M, 6rp2:L, 6rp2:M, 4ue3:LLL, 4ue3:MMM, 3uqy:L, 3uqy:M, 3usc:L, 3usc:M, 3use:L, 3use:M
11 6rtp:B 484 540 0.3783 0.4174 0.3741 1.60e-104 5jsh:B, 5jsk:B, 5jsu:B, 5jsy:B, 5jt1:B, 6ru9:B, 6ruc:B, 2wpn:B, 6z7r:B, 6z7r:D, 6z8j:B, 6z8j:D, 6z8m:B, 6z8o:B, 6z8o:D, 6z9g:B, 6z9g:D, 6z9g:F, 6z9g:H, 6z9o:B, 6za1:B, 3ze6:B, 3ze7:B, 3ze8:B, 3ze9:B, 3zea:B
12 4kl8:L 489 540 0.3858 0.4213 0.3815 1.23e-103 1cc1:L, 4kl8:M, 4kn9:L, 4kn9:M, 4ko1:L, 4ko1:M, 4ko2:L, 4ko2:M, 4ko3:L, 4ko3:M, 4ko4:L, 4ko4:M
13 8dqv:A 513 575 0.3127 0.3255 0.2904 3.63e-60 8dqv:C, 7utd:A, 7utd:C, 7utd:E, 7utd:G, 7utd:I, 7utd:K, 7utd:M, 7utd:O, 7uur:C, 7uur:F, 7uus:A, 7uus:C, 7uus:E, 7uus:G, 7uus:I, 7uus:K, 7uus:M, 7uus:O
14 5aa5:G 561 589 0.2753 0.2620 0.2496 1.01e-40 5aa5:C, 5aa5:E, 5aa5:K, 5aa5:I, 5aa5:L
15 7t2r:D 447 545 0.2603 0.3110 0.2550 3.70e-20 7t2r:I, 7t30:D, 7t30:I
16 5odc:F 447 114 0.0880 0.1051 0.4123 2.63e-19 5odc:L, 5odh:F, 5odh:L, 5odi:F, 5odi:L, 5odq:F, 5odq:L, 5odr:F, 5odr:L
17 5odc:F 447 126 0.0768 0.0917 0.3254 3.98e-05 5odc:L, 5odh:F, 5odh:L, 5odi:F, 5odi:L, 5odq:F, 5odq:L, 5odr:F, 5odr:L
18 4ci0:A 385 115 0.0824 0.1143 0.3826 8.57e-18 4omf:A
19 4ci0:A 385 87 0.0449 0.0623 0.2759 1.07e-04 4omf:A
20 6qgr:A 437 547 0.2228 0.2723 0.2176 7.97e-17 6qgt:A, 6qii:A
21 5xf9:D 455 127 0.0824 0.0967 0.3465 8.31e-16 5xf9:H, 5xfa:D, 5xfa:H
22 5xf9:D 455 193 0.0993 0.1165 0.2746 1.31e-05 5xf9:H, 5xfa:D, 5xfa:H
23 7z0s:E 532 95 0.0581 0.0583 0.3263 8.01e-10 7z0t:E
24 6cfw:L 374 84 0.0449 0.0642 0.2857 2.48e-07
25 6cfw:L 374 95 0.0543 0.0775 0.3053 5.22e-05
26 6xfr:B 216 63 0.0431 0.1065 0.3651 1.2 6xfr:A
27 5e9g:D 486 187 0.0824 0.0905 0.2353 1.9
28 5e9f:B 501 190 0.0805 0.0858 0.2263 2.1 5e9f:C, 5e9g:C
29 8b9z:D 430 102 0.0487 0.0605 0.2549 3.6 8esz:S2
30 6btm:B 948 80 0.0487 0.0274 0.3250 3.9
31 5iby:A 321 131 0.0524 0.0872 0.2137 3.9 5ich:A, 5ich:B, 5icl:A, 5icl:B, 5idh:A
32 7lte:A 262 50 0.0337 0.0687 0.3600 6.7 7lte:C, 7ltr:A, 7ltr:H, 7lts:A, 7lts:C, 8t1s:A, 8t1s:C, 8t1t:A, 8t1t:C
33 8dgd:A 167 65 0.0412 0.1317 0.3385 7.6
34 8av6:I 109 49 0.0300 0.1468 0.3265 8.1 6fml:I, 8oop:I
35 4j9v:A 456 51 0.0318 0.0373 0.3333 8.3 4j9u:H, 4j9u:G, 4j9u:E, 4j9u:F, 4j9v:B, 6v4k:E, 6v4k:F, 6v4k:G, 6v4k:H, 6v4l:C, 6v4l:D
36 3cxm:A 242 73 0.0449 0.0992 0.3288 8.4
37 1gm9:A 207 56 0.0318 0.0821 0.3036 9.4 1fxh:A, 1fxv:A, 1k7d:A, 1kec:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218