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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SSPNEFLNKVIGKKVLIRLSSGVDYKGILSCLDGYMNLALERTEEYVNGKKTNVYGDAFIRGNNVLYVSAL

The query sequence (length=71) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6ppq:F 71 71 1.0000 1.0000 1.0000 1.29e-46 6ppn:F, 6ppn:N, 6ppp:F, 6ppp:N, 6ppv:F
2 6qw6:66 72 70 0.6479 0.6389 0.6571 2.43e-33 6qx9:66
3 4wzj:MM 80 70 0.4507 0.4000 0.4571 2.41e-18 7abg:b, 7abi:b, 6ahd:Q, 6ahd:d, 7b0y:f, 8c6j:q, 8c6j:f, 8ch6:h, 8ch6:2, 7dvq:f, 7dvq:m, 9fmd:m, 9fmd:f, 8h6e:5d, 8h6e:4d, 8h6j:5d, 8h6j:4d, 8h6k:5d, 8h6k:4d, 8h6l:5d, 8h6l:4d, 8i0p:d, 8i0r:d, 8i0s:d, 8i0s:i, 8i0t:d, 8i0t:i, 8i0u:d, 8i0u:i, 8i0v:d, 8i0v:i, 8i0w:d, 8i0w:m, 6id1:f, 5mqf:i, 5mqf:b, 5o9z:i, 4pjo:F, 4pjo:f, 4pjo:T, 4pjo:t, 8q7q:f, 8q7v:f, 8q7w:f, 8q7x:f, 8q91:m, 6qdv:q, 6qdv:f, 8qo9:2f, 8qo9:5f, 8qo9:4f, 7qtt:h, 6qw6:4f, 6qw6:5f, 6qx9:1f, 6qx9:5f, 6qx9:2f, 6qx9:4f, 8qxd:2f, 8qxd:4f, 8qxd:5f, 8qzs:5f, 8qzs:2f, 8qzs:4f, 8r08:1f, 8r08:2f, 8r08:4f, 8r08:5f, 8r09:2f, 8r09:5f, 8r09:4f, 8r0a:5f, 8r0a:2f, 8r0a:4f, 8r0b:2f, 8r0b:4f, 8r0b:5f, 8rc0:m, 8rm5:2f, 8rm5:5f, 8rm5:4f, 8ro2:f, 6v4x:F, 7vpx:m, 7w59:f, 7w59:m, 7w5a:f, 7w5a:m, 7w5b:f, 7w5b:m, 4wzj:F, 4wzj:M, 4wzj:T, 4wzj:FF, 4wzj:TT, 4wzj:FFF, 4wzj:MMM, 4wzj:TTT, 4wzj:FFFF, 4wzj:MMMM, 4wzj:TTTT, 5xjc:f, 5xjc:m, 8y6o:f, 8y6o:m, 8y6o:t, 8y7e:m, 5yzg:f, 5yzg:m, 5z56:m, 5z57:m, 5z58:m
4 3jb9:I 73 67 0.4930 0.4795 0.5224 1.10e-17 3jb9:n
5 8ro0:f 72 69 0.4507 0.4444 0.4638 5.92e-17 8ro1:f
6 5vsu:F 77 73 0.4225 0.3896 0.4110 4.06e-12 6aso:F
7 7b9v:q 75 71 0.3803 0.3600 0.3803 5.81e-11 7b9v:f, 6bk8:b, 7dco:j, 6exn:q, 6exn:f, 6g90:f, 6g90:x, 5gam:f, 5gan:q, 5gan:f, 5gao:q, 5gm6:h, 5gmk:h, 5gmk:w, 6j6g:h, 6j6g:w, 6j6h:h, 6j6h:w, 6j6n:h, 6j6n:w, 6j6q:h, 6j6q:w, 5lj3:f, 5lj5:f, 5mps:f, 5mq0:f, 6n7p:P, 6n7r:P, 6n7x:P, 5nrl:x, 5nrl:q, 5nrl:f, 7oqc:f, 8w2o:P, 5wsg:h, 5wsg:H, 5y88:c, 5y88:j, 5ylz:c, 5ylz:j, 5zwm:U, 5zwm:j, 5zwn:f, 5zwo:U, 5zwo:j
8 1lnx:A 74 67 0.3944 0.3784 0.4179 1.64e-10 1lnx:B, 1lnx:C, 1lnx:D, 1lnx:E, 1lnx:F, 1lnx:G
9 1i5l:C 74 70 0.3521 0.3378 0.3571 3.40e-10 1i5l:E, 1i5l:F, 1i5l:G, 1i5l:J, 1i5l:K, 1i5l:L, 1i5l:A, 1i5l:B, 1i5l:H
10 1loj:C 77 69 0.3239 0.2987 0.3333 1.13e-09 1loj:A, 1loj:B, 1loj:D, 1loj:E, 1loj:F, 1loj:G, 1loj:H, 1loj:I, 1loj:J, 1loj:K, 1loj:L, 1loj:M, 1loj:N
11 6v4x:G 77 71 0.3380 0.3117 0.3380 9.70e-08 7a5p:k, 7a5p:g, 7abg:k, 7abi:k, 6ah0:n, 6ahd:S, 6ahd:f, 6ahd:n, 7b0y:h, 8c6j:r, 8c6j:g, 8ch6:m, 8ch6:9, 7dvq:g, 7dvq:n, 7evo:d, 9fmd:n, 9fmd:g, 8h6e:5f, 8h6e:4f, 8h6e:2f, 8h6j:5f, 8h6j:4f, 8h6j:2f, 8h6k:5f, 8h6k:4f, 8h6k:2f, 8h6l:5f, 8h6l:4f, 8h6l:2f, 8hk1:d, 8i0p:k, 8i0r:k, 8i0s:f, 8i0s:k, 8i0t:k, 8i0u:f, 8i0u:k, 8i0v:k, 8i0w:n, 6icz:g, 6id0:g, 6id1:g, 5mqf:k, 5mqf:d, 5o9z:k, 4pjo:G, 4pjo:g, 4pjo:U, 4pjo:u, 8q7q:g, 8q7v:g, 8q7w:g, 8q7x:g, 8q91:n, 6qdv:r, 6qdv:g, 8qo9:2g, 8qo9:4g, 7qtt:m, 6qw6:4g, 6qw6:5g, 6qx9:1g, 6qx9:5g, 6qx9:2g, 6qx9:4g, 8qxd:2g, 8qxd:4g, 8qxd:5g, 8qzs:5g, 8qzs:2g, 8qzs:4g, 8r08:1g, 8r08:2g, 8r08:4g, 8r08:5g, 8r09:2g, 8r09:5g, 8r09:4g, 8r0a:5g, 8r0a:2g, 8r0a:4g, 8r0b:2g, 8r0b:4g, 8r0b:5g, 8rc0:n, 8rm5:2g, 8rm5:5g, 8rm5:4g, 8ro2:g, 7vpx:d, 7vpx:n, 7w59:g, 7w59:n, 7w5a:g, 7w5a:n, 7w5b:g, 7w5b:n, 4wzj:G, 4wzj:N, 4wzj:U, 4wzj:GG, 4wzj:NN, 4wzj:UU, 4wzj:GGG, 4wzj:NNN, 4wzj:UUU, 4wzj:GGGG, 4wzj:NNNN, 4wzj:UUUU, 5xjc:g, 5xjc:n, 6y53:k, 6y5q:k, 8y6o:g, 8y6o:n, 8y6o:u, 8y7e:n, 5yzg:g, 5yzg:n, 5z56:g, 5z56:n, 5z57:g, 5z57:n, 5z58:g, 5z58:n
12 1m8v:A 72 70 0.3099 0.3056 0.3143 2.47e-07 1m8v:M, 1m8v:C, 1m8v:K, 1m8v:F, 1m8v:H, 1m8v:E, 1m8v:I, 1m8v:D, 1m8v:J, 1m8v:B, 1m8v:L, 1m8v:G, 1m8v:N
13 6ppn:D 88 67 0.3380 0.2727 0.3582 1.16e-06 6ppn:L, 6ppp:D, 6ppp:L, 6ppq:D, 6ppv:D
14 3jb9:J 73 66 0.3099 0.3014 0.3333 5.93e-05 3jb9:o
15 5mkn:d 72 69 0.3380 0.3333 0.3478 1.10e-04 5mki:C, 5mki:D, 5mki:E, 5mki:F, 5mki:G, 5mki:I, 5mki:J, 5mki:K, 5mki:L, 5mkn:A, 5mkn:G, 5mkn:B, 5mkn:C, 5mkn:D, 5mkn:E, 5mkn:F, 5mkn:H, 5mkn:I, 5mkn:J, 5mkn:K, 5mkn:L, 5mkn:M, 5mkn:N, 5mkn:O, 5mkn:P, 5mkn:Q, 5mkn:R, 5mkn:T, 5mkn:U, 5mkn:V, 5mkn:W, 5mkn:X, 5mkn:Y, 5mkn:Z, 5mkn:a, 5mkn:b
16 6tfl:A 62 68 0.2676 0.3065 0.2794 3.81e-04 6tfl:B, 6tfl:C, 6tfl:D, 6tfl:E, 6tfl:F, 6tfl:G, 6tfl:H, 6tfl:I, 6tfl:J, 6tfl:K, 6tfl:L, 6tfl:M, 6tfl:N
17 3jb9:F 82 62 0.2817 0.2439 0.3226 6.74e-04 3jb9:f
18 6ppn:B 94 65 0.2817 0.2128 0.3077 0.002 6ppn:J, 6ppp:B, 6ppp:J, 6ppq:B, 6ppv:B
19 5gan:4 74 66 0.2958 0.2838 0.3182 0.005 4m7a:N, 4m7a:G, 4m7d:N, 5nrl:j, 5vsu:D
20 6aso:D 59 47 0.2254 0.2712 0.3404 0.005
21 8ro0:n 77 70 0.2817 0.2597 0.2857 0.008 8ro0:g, 8ro1:g
22 4m7a:F 66 57 0.2817 0.3030 0.3509 0.009
23 3swn:A 76 65 0.2676 0.2500 0.2923 0.012 6ppq:E, 6ppv:E, 3swn:D, 3swn:P, 3swn:S
24 8ro0:a 81 66 0.2535 0.2222 0.2727 0.016 8ro1:a
25 6ppq:A 69 68 0.3239 0.3333 0.3382 0.021 6ppv:A
26 6qw6:62 95 66 0.2676 0.2000 0.2879 0.025 6ahd:q, 8h6e:6a, 8h6j:6a, 8h6k:6a, 8h6l:6a, 6qx9:62
27 8ro0:b 98 56 0.1831 0.1327 0.2321 0.035 8ro1:b
28 8ro0:c 80 64 0.2817 0.2500 0.3125 0.038 8ro1:c
29 6v4x:B 76 52 0.1972 0.1842 0.2692 0.069
30 7k17:B 3645 17 0.1549 0.0030 0.6471 0.085 7k17:A
31 6qw6:64 73 67 0.2676 0.2603 0.2836 0.11 6qx9:64
32 3jb9:E 98 48 0.2254 0.1633 0.3333 0.11 3jb9:b
33 6exn:r 75 74 0.2958 0.2800 0.2838 0.15 7b9v:r, 7b9v:g, 6bk8:d, 7dco:k, 6exn:g, 6g90:g, 6g90:y, 5gam:g, 5gan:r, 5gan:g, 5gao:r, 5gm6:j, 5gmk:j, 5gmk:x, 6j6g:j, 6j6g:x, 6j6h:j, 6j6h:x, 6j6n:j, 6j6n:x, 6j6q:j, 6j6q:x, 5lj3:g, 5lj5:g, 5mps:g, 5mq0:g, 6n7p:Q, 6n7r:Q, 6n7x:Q, 5nrl:y, 5nrl:r, 5nrl:g, 7oqb:y, 7oqc:g, 7oqe:y, 8w2o:Q, 5wsg:j, 5wsg:K, 5y88:d, 5y88:k, 5ylz:d, 5ylz:k, 5zwm:V, 5zwm:k, 5zwn:g, 5zwo:k
34 6g90:d 93 66 0.2254 0.1720 0.2424 0.30 7b9v:n, 7b9v:d, 6bk8:o, 6bk8:g, 7dco:l, 6exn:n, 6exn:d, 6g90:v, 5gam:d, 5gan:n, 5gan:d, 5gao:n, 5gm6:l, 5gmk:l, 5gmk:y, 6j6g:l, 6j6g:y, 6j6h:l, 6j6h:y, 6j6n:l, 6j6n:y, 6j6q:l, 6j6q:y, 3jcm:J, 3jcm:R, 5lj3:d, 5lj3:n, 5lj5:d, 5lj5:n, 5mps:d, 5mq0:n, 5mq0:d, 6n7p:N, 6n7r:N, 6n7x:N, 5nrl:v, 5nrl:n, 5nrl:d, 7oqb:v, 7oqc:d, 7oqe:d, 7oqe:v, 8w2o:N, 5wsg:l, 5wsg:U, 5y88:e, 5y88:l, 5ylz:e, 5ylz:l, 5zwm:S, 5zwm:d, 5zwm:l, 5zwn:d, 5zwo:d, 5zwo:S
35 1k39:B 271 50 0.2817 0.0738 0.4000 0.88 1hnu:A, 1k39:A, 1k39:C, 4zdb:A, 4zdb:B, 4zdb:C, 4zdc:A, 4zdc:B, 4zdc:C
36 7otm:A 3656 21 0.1549 0.0030 0.5238 1.3 7otp:A, 7otv:A, 7otw:A, 7oty:A
37 6zhe:A 3768 17 0.1408 0.0027 0.5882 1.4
38 7k1j:A 3584 21 0.1690 0.0033 0.5714 1.5 7k19:A
39 7k1k:A 3604 21 0.1690 0.0033 0.5714 1.5 7k1b:A
40 7nfc:A 3562 18 0.1268 0.0025 0.5000 2.0 8bh3:S, 8bh3:A, 8bhv:A, 8bhv:F, 8bhy:A, 8bhy:S, 8bot:F, 8bot:S, 7nfc:F
41 7mxw:Z 350 51 0.1831 0.0371 0.2549 2.4 7mxq:Z, 7mxr:Z, 7mxs:Z, 7mxt:Z, 7mxu:Z, 7mxv:Z, 7mxx:Z, 3qe9:Y, 3qe9:Z, 3qea:Z, 3qeb:Z, 5uzv:Z, 5v04:Z, 5v05:Z, 5v06:Z, 5v07:Z, 5v08:Z, 5v09:Z, 5v0a:Z, 5v0b:Z, 5v0c:Z, 5v0d:Z, 5v0e:Z
42 5h9m:A 190 30 0.1549 0.0579 0.3667 2.9 5h9m:B
43 7abg:j 81 47 0.1831 0.1605 0.2766 3.2 7a5p:j, 7a5p:e, 7abi:j, 6ah0:c, 6ahd:e, 7b0y:g, 8c6j:p, 8c6j:e, 8ch6:i, 8ch6:1, 7dvq:e, 7dvq:l, 9fmd:l, 9fmd:e, 8h6e:5e, 8h6e:4e, 8h6j:5e, 8h6j:4e, 8h6k:5e, 8h6l:5e, 8i0p:e, 8i0p:j, 8i0r:e, 8i0r:j, 8i0s:e, 8i0s:j, 8i0t:e, 8i0t:j, 8i0u:e, 8i0u:j, 8i0v:e, 8i0v:j, 8i0w:e, 8i0w:l, 6icz:e, 6id0:e, 6id1:e, 5mqf:j, 5mqf:c, 5o9z:j, 4pjo:E, 4pjo:e, 4pjo:S, 4pjo:s, 8q7q:e, 8q7v:e, 8q7w:e, 8q7x:e, 6qdv:p, 6qdv:e, 8qo9:2e, 8qo9:5e, 8qo9:4e, 7qtt:i, 6qw6:4e, 6qw6:5e, 6qx9:1e, 6qx9:5e, 6qx9:2e, 6qx9:4e, 8qxd:2e, 8qxd:4e, 8qzs:5e, 8qzs:2e, 8qzs:4e, 8r08:1e, 8r08:2e, 8r08:4e, 8r09:2e, 8r09:5e, 8r09:4e, 8r0a:5e, 8r0a:2e, 8r0a:4e, 8r0b:4e, 8r0b:5e, 8rm5:2e, 8rm5:5e, 8rm5:4e, 8ro2:e, 6v4x:E, 7vpx:l, 7w59:e, 7w59:l, 7w5a:e, 7w5a:l, 7w5b:e, 7w5b:l, 4wzj:E, 4wzj:L, 4wzj:S, 4wzj:EE, 4wzj:LL, 4wzj:SS, 4wzj:EEE, 4wzj:LLL, 4wzj:SSS, 4wzj:EEEE, 4wzj:LLLL, 4wzj:SSSS, 5xjc:e, 5xjc:l, 8y6o:e, 8y6o:l, 8y6o:s, 8y7e:l, 5yzg:e, 5yzg:l, 5z56:e, 5z56:l, 5z57:e, 5z57:l, 5z58:e, 5z58:l
44 6t2s:AAA 241 33 0.1831 0.0539 0.3939 3.5 6t2s:BBB, 6t2s:CCC
45 7sgl:A 3852 17 0.1408 0.0026 0.5882 3.6
46 8ez9:L 3662 18 0.1690 0.0033 0.6667 3.7 8ez9:C
47 8eza:L 3720 18 0.1690 0.0032 0.6667 3.7 8eza:C, 7lt3:C, 7lt3:L
48 8bot:A 3528 12 0.1268 0.0026 0.7500 4.1
49 7nfe:A 3585 12 0.1268 0.0025 0.7500 4.1
50 7k1n:A 3634 12 0.1268 0.0025 0.7500 4.1 7z88:A
51 5y3r:C 3636 12 0.1268 0.0025 0.7500 4.1
52 7k0y:A 3669 12 0.1268 0.0025 0.7500 4.1
53 7z87:A 3689 12 0.1268 0.0024 0.7500 4.1
54 6zha:A 3707 12 0.1268 0.0024 0.7500 4.1 6zh8:A
55 8ezb:C 3724 12 0.1268 0.0024 0.7500 4.1 8ezb:L
56 6zhe:F 3731 12 0.1268 0.0024 0.7500 4.1
57 7sud:A 3740 12 0.1268 0.0024 0.7500 4.1
58 7su3:A 3802 12 0.1268 0.0024 0.7500 4.1
59 2afh:B 522 42 0.1690 0.0230 0.2857 4.2 2afh:D, 2afi:B, 2afi:D, 2afi:J, 2afi:L, 6bbl:B, 6bbl:D, 8bts:B, 8bts:D, 8bts:I, 8bts:L, 5bvg:B, 5bvg:D, 5bvh:B, 5bvh:D, 6cdk:B, 6cdk:D, 8crs:D, 8crs:B, 5cx1:B, 5cx1:D, 5cx1:F, 5cx1:H, 5cx1:J, 5cx1:L, 5cx1:N, 5cx1:P, 8dbx:B, 8dbx:D, 8dby:B, 8dby:D, 8dfc:B, 8dfc:D, 8dfd:B, 8dfd:D, 8dpn:B, 8dpn:D, 8e3t:B, 8e3t:D, 8e3u:B, 8e3u:D, 8e3v:B, 8e3v:D, 8enl:B, 8enl:D, 8enm:B, 8enm:D, 8enn:B, 8enn:D, 8eno:B, 8eno:D, 1fp4:B, 1fp4:D, 1g20:B, 1g20:D, 1g21:B, 1g21:D, 7jrf:B, 7jrf:D, 3k1a:B, 3k1a:D, 1l5h:B, 1m1n:B, 1m1n:D, 1m1n:F, 1m1n:H, 1m1y:B, 1m1y:D, 1m1y:J, 1m1y:L, 1m34:B, 1m34:D, 1m34:J, 1m34:L, 7mci:B, 7mci:D, 2min:B, 2min:D, 3min:B, 3min:D, 1n2c:B, 1n2c:D, 4nd8:B, 4nd8:D, 6o7l:B, 6o7l:D, 6o7m:B, 6o7m:D, 6o7n:B, 6o7n:D, 6o7o:B, 6o7o:D, 6o7p:B, 6o7p:D, 6o7q:B, 6o7q:D, 6o7r:B, 6o7r:D, 6o7s:B, 6o7s:D, 6op1:B, 6op1:D, 6op2:B, 6op2:D, 6op3:B, 6op3:D, 6op4:B, 6op4:D, 8p8g:B, 8p8g:D, 4tku:B, 4tku:D, 4tkv:B, 4tkv:D, 3u7q:B, 3u7q:D, 6ug0:B, 6ug0:D, 7ut6:B, 7ut6:D, 7ut7:B, 7ut7:D, 7ut8:B, 7ut8:D, 7ut9:B, 7ut9:D, 7uta:B, 7uta:D, 5vq4:B, 5vq4:D, 6vxt:B, 6vxt:D, 4wna:B, 4wna:D, 4wza:B, 4wza:D, 4wzb:B, 4wzb:D, 4xpi:B, 4xpi:D
60 4c9z:A 193 30 0.1549 0.0570 0.3667 4.7 2a25:A, 2an6:A, 2an6:B, 2an6:C, 2an6:D, 4c9z:B, 4ca1:A, 4ca1:B, 8heo:B, 8heo:A, 4i7b:A, 4i7b:C, 4i7c:A, 4i7c:C, 4i7d:A, 4i7d:C, 1k2f:A, 1k2f:B, 5wzz:C, 5wzz:B, 5wzz:A, 5wzz:D, 4x3g:A, 4x3g:B
61 1fxy:A 228 44 0.2394 0.0746 0.3864 4.9
62 3f0a:A 159 27 0.1549 0.0692 0.4074 7.3 3k9u:A, 3k9u:B, 3ne7:A
63 2ra3:A 224 44 0.2394 0.0759 0.3864 7.8 2ra3:B, 1trn:A, 1trn:B, 4wwy:B, 4wxv:A, 4wxv:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218