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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SKPTLKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLP
ISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMG
SCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE
NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNE
AFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQGEYGLASICNGGGGASAMLIQKL

The query sequence (length=393) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2ib8:D 393 393 1.0000 1.0000 1.0000 0.0 2f2s:A, 2f2s:B, 2f2s:C, 2f2s:D, 2ib8:A, 2ib8:B, 2ib8:C, 2ib9:A, 2ib9:B, 2ib9:C, 2ib9:D, 2ibu:A, 2ibu:B, 2ibu:C, 2ibu:D, 2ibw:A, 2ibw:B, 2ibw:C, 2ibw:D, 2iby:A, 2iby:B, 2iby:C, 2iby:D
2 6bn2:A 393 393 0.5827 0.5827 0.5827 1.97e-159
3 6bjb:A 384 389 0.5522 0.5651 0.5578 9.33e-143 6bjb:B
4 6l2c:A 402 394 0.5038 0.4925 0.5025 3.45e-136 6l2c:B, 6l2c:C, 6l2c:D
5 6bja:A 382 389 0.4911 0.5052 0.4961 4.69e-127
6 6aqp:C 399 396 0.4936 0.4862 0.4899 2.88e-121 6aqp:A, 6aqp:B, 6aqp:D, 6are:A, 6are:B, 6are:C, 6are:D
7 7cw5:B 394 390 0.4733 0.4721 0.4769 3.08e-116 7cw5:A
8 4xl4:A 392 394 0.4606 0.4617 0.4594 4.06e-112 4xl4:B
9 8gqn:A 390 391 0.4631 0.4667 0.4655 1.04e-110 8gqn:B, 8gqn:C, 8gqn:D
10 4o9c:C 393 393 0.4529 0.4529 0.4529 1.71e-103
11 1ou6:A 392 391 0.4249 0.4260 0.4271 1.69e-100 1dlv:A, 1dlv:B, 1dlv:C, 1dlv:D, 1dm3:A, 1dm3:B, 1dm3:C, 1dm3:D, 7lbz:A, 7lbz:B, 7lbz:C, 7lbz:D, 7lca:A, 7lca:B, 7lca:C, 7lca:D, 7lcl:A, 7lcl:B, 7lcl:C, 7lcl:D, 7ld2:A, 7ld2:B, 7ld2:C, 7ld2:D, 7ldc:A, 7ldc:B, 7ldc:C, 7ldc:D, 7ldt:A, 7ldt:B, 7ldt:C, 7ldt:D, 7ldu:A, 7ldu:B, 7ldu:C, 7ldu:D, 7ldv:A, 7ldv:B, 7ldv:C, 7ldv:D, 7ldw:A, 7ldw:B, 7ldw:C, 7ldw:D, 1m1o:A, 1m1o:B, 1m3z:A, 1m3z:B, 1m3z:C, 1m3z:D, 1nl7:A, 1nl7:B, 1ou6:B, 1qfl:A, 1qfl:B, 1qfl:C, 1qfl:D, 2vtz:A, 2vtz:B, 2vtz:C, 2vtz:D, 2vu0:A, 2vu0:B, 2vu1:A, 2vu1:B, 2vu2:A, 2vu2:B, 2wkt:A, 2wkt:B, 2wkt:C, 2wkt:D, 2wku:A, 2wku:B, 2wkv:A, 2wkv:B, 2wkv:C, 2wkv:D, 2wl4:A, 2wl4:B, 2wl5:A, 2wl5:B, 2wl5:C
12 1wl4:A 394 390 0.4326 0.4315 0.4359 7.11e-100
13 8jg2:A 393 395 0.4249 0.4249 0.4228 8.32e-99 8jg2:B
14 5f38:D 394 394 0.4427 0.4416 0.4416 9.47e-95 5f38:B, 5f38:C
15 4c2j:D 395 394 0.4046 0.4025 0.4036 2.98e-82 4c2j:A, 4c2j:B, 4c2j:C
16 7fea:B 396 391 0.3664 0.3636 0.3683 3.21e-80 7ei4:A, 7ei4:B, 7ei4:C, 7ei4:D, 7fea:A, 7fea:C, 7fea:D
17 5bz4:K 400 404 0.3588 0.3525 0.3490 1.46e-70 5bz4:B, 5bz4:D, 5bz4:F, 5bz4:H
18 6pcb:A 403 403 0.3791 0.3697 0.3697 6.84e-67 6pcb:B, 6pcb:C, 6pcb:D, 6pcc:A, 6pcc:B, 6pcc:C, 6pcc:D, 6pcd:A, 6pcd:B, 6pcd:D
19 2d3t:C 390 397 0.3410 0.3436 0.3375 5.43e-56 2d3t:D, 1wdk:C, 1wdk:D, 1wdl:C, 1wdl:D, 1wdm:C, 1wdm:D
20 4ubt:A 396 399 0.3486 0.3460 0.3434 4.12e-55 4ubt:B, 4ubt:C, 4ubt:D, 4ubu:A, 4ubu:B, 4ubu:C, 4ubu:D, 4ubu:E, 4ubu:F, 4ubu:G, 4ubu:H, 4ubv:A, 4ubv:B
21 7o4t:D 403 419 0.3308 0.3226 0.3103 7.39e-52 4b3i:C, 4b3j:C, 4b3j:D, 7o1i:D, 7o1l:D, 7o4r:C, 7o4r:D, 7o4s:C, 7o4s:D, 7o4t:C, 8opu:C, 8opu:D, 8opx:C, 8opx:D, 8opy:D, 8oql:C, 8oql:D, 8oqm:D, 8oqo:C, 8oqo:D, 8oqp:C, 8oqp:D, 8oqs:C, 8oqs:D, 8pf8:C, 8pf8:D
22 8gqm:A 377 391 0.3206 0.3342 0.3223 2.06e-49
23 6hsj:B 390 363 0.2087 0.2103 0.2259 2.01e-06 6hsp:B
24 6esq:A 392 89 0.0865 0.0867 0.3820 3.03e-06 6esq:B, 6esq:C, 6esq:D
25 6esq:A 392 188 0.1145 0.1148 0.2394 0.011 6esq:B, 6esq:C, 6esq:D
26 1ox0:A 414 45 0.0483 0.0459 0.4222 0.009 2alm:A, 1oxh:A, 1oxh:B, 1oxh:C, 1oxh:D
27 5lnq:A 430 150 0.0840 0.0767 0.2200 0.026 5lnq:B, 5lnq:D, 5lot:A, 5lot:B, 5lot:D, 3zbn:A, 3zbn:B, 3zbn:D
28 4yzo:C 347 79 0.0687 0.0778 0.3418 0.053 4yzo:D
29 7s6c:B 891 66 0.0534 0.0236 0.3182 0.13
30 8cg5:A 1282 44 0.0382 0.0117 0.3409 0.17 6fij:B
31 8cg6:A 1208 44 0.0382 0.0124 0.3409 0.18
32 7pyt:B 392 142 0.0865 0.0867 0.2394 0.22 7pyt:D, 7yxm:B, 7yxm:D
33 7m7f:A 1390 102 0.0611 0.0173 0.2353 0.22 2fr0:A, 2fr1:A, 7m7i:A
34 7b93:R 96 36 0.0331 0.1354 0.3611 0.33 7ak5:R, 7ak6:R, 8c2s:R, 8ca3:R, 6g2j:R, 6g72:R, 8iao:R, 8iap:R, 8ib4:R, 8ib5:R, 8ib9:R, 8iba:R, 8ibd:R, 8ibe:R, 8ic2:R, 8ic3:R, 8olt:R, 8om1:R, 7psa:R, 8pw5:7, 8pw6:7, 8pw7:7, 8rgp:7, 8rgq:7, 8rgr:7, 8rgt:7, 6zr2:R, 6ztq:R
35 7l4l:A 412 40 0.0433 0.0413 0.4250 0.35 1b3n:A, 3g0y:A, 3g11:A, 2gfx:A, 3hnz:A, 3ho2:A, 3ho9:A, 3i8p:A, 7l4e:A, 7l4l:B, 6okg:A, 6olt:A
36 8q0a:R 96 36 0.0305 0.1250 0.3333 0.63 7dgq:I, 7dgr:I, 7dgs:I, 7dgz:I, 7dh0:I, 7dkf:I2, 5lnk:b, 5o31:R, 8q0f:R, 8q0j:R, 8q0m:R, 8q0o:R, 8q0q:R, 8q1p:R, 8q1u:R, 8q1y:R, 8q25:R, 8q45:R, 8q46:R, 8q47:R, 8q48:R, 8q49:R, 8q4a:R, 6q9d:S6, 6qa9:S6, 6qbx:S6, 6qc2:S6, 6qc3:S6, 6qc4:S6, 6qc5:S6, 6qc6:S6, 6qc7:S6, 6qc8:S6, 7qsd:R, 7qsk:R, 7qsl:R, 7qsm:R, 7qsn:R, 7qso:R, 7r41:R, 7r42:R, 7r43:R, 7r44:R, 7r45:R, 7r46:R, 7r47:R, 7r48:R, 7r4c:R, 7r4d:R, 7r4f:R, 7r4g:R, 8ud1:1R, 8ueo:1R, 8uep:1R, 8ueq:1R, 8uer:1R, 8ues:1R, 8uet:1R, 8ueu:1R, 8uev:1R, 8uew:1R, 8uex:1R, 8uey:1R, 8uez:1R, 8ugh:1R, 8ugi:1R, 8ugj:1R, 8ugn:1R, 8ugn:5R, 8ugr:1R, 8ugr:5R, 7v2c:T, 7v2d:T, 7v2e:T, 7v2f:T, 7v2h:T, 7v2k:T, 7v2r:T, 7v30:T, 7v31:T, 7v32:T, 7v33:T, 7v3m:T, 7vb7:T, 7vbn:T, 7vbz:T, 7vwj:T, 7vxp:T, 7vxu:T, 7vy8:T, 7vya:T, 7vyf:T, 7vyh:T, 7vyn:T, 7vz1:T, 7vzv:T, 7vzw:T, 7w00:T, 7w0h:T, 7w0r:T, 7w0y:T, 7w1o:T, 7w1p:T, 7w1t:T, 7w1u:T, 7w1v:T, 7w1z:T, 7w20:T, 7w2k:T, 7w2l:T, 7w2r:T, 7w2u:T, 7w2y:T, 7w31:T, 7w32:T, 7w35:T, 7w4c:T, 7w4d:T, 7w4e:T, 7w4f:T, 7w4g:T, 7w4j:T, 7w4k:T, 7w4l:T, 7w4m:T, 7w4n:T, 7w4q:T, 7zd6:b, 7zdh:b, 7zdj:b, 7zdm:b, 7zdp:b, 7zeb:b, 6zk9:b, 6zkc:b, 6zkd:b, 6zke:b, 6zkf:b, 6zkg:b, 6zkh:b, 6zki:b, 6zkj:b, 6zkk:b, 6zkl:b, 6zkm:b, 6zkn:b, 6zko:b, 6zkp:b, 6zkq:b, 6zkr:b, 6zks:b, 6zkt:b, 6zku:b, 6zkv:b
37 2ix4:A 431 30 0.0382 0.0348 0.5000 1.1 2ix4:B
38 4jv3:A 407 122 0.0814 0.0786 0.2623 1.3 3mqd:A, 3u0e:A, 3u0f:A
39 5mg5:L 396 79 0.0611 0.0606 0.3038 1.8 5mg5:C, 5mg5:O, 5mg5:R
40 4c6v:A 415 46 0.0458 0.0434 0.3913 1.9 4c6u:A, 4c6w:A, 4c6w:B, 4c6x:A, 4c6x:B, 4c6z:A, 4c6z:B, 4c70:A, 4c70:B, 4c71:A, 4c71:B, 4c72:A, 4c72:B, 4c73:A, 4c73:B, 5ld8:A, 5ld8:B, 6p9k:A, 6p9l:A, 6p9m:A, 5w2o:A, 5w2p:A, 5w2q:A, 5w2s:A, 2wge:A, 2wgg:A, 2wgg:B, 2wgg:C, 2wgg:D, 2wgg:E, 2wgg:F, 2wgg:G, 2wgg:H, 6y2i:AAA, 6y2i:BBB, 6y2j:AAA, 6y2j:BBB, 6y2j:CCC, 6y2j:DDD, 6y2j:EEE, 6y2j:FFF, 6y2j:GGG, 6y2j:HHH
41 8cuy:A 1016 95 0.0585 0.0226 0.2421 2.3
42 2iwz:A 426 56 0.0509 0.0469 0.3571 2.6 2iwz:B
43 6tg9:A 949 114 0.0687 0.0285 0.2368 2.8 6tg9:E, 6tga:A, 6tga:E
44 8cou:A 413 42 0.0382 0.0363 0.3571 3.5 4b7v:A, 4b7v:B, 8cn2:B, 8cn2:A, 8cn4:A, 8cn4:B, 8cn5:B, 8cn5:A, 8cn7:A, 8cn7:B, 8cne:A, 8cne:B, 8cng:A, 8cng:B, 8cou:B, 8cov:A, 8cov:B, 4jb6:A, 4jb6:B, 4jpf:A, 7oc0:A, 7oc0:B, 7oc1:A, 7oc1:B, 8pd1:A, 8pd1:B, 8pfz:A, 8pfz:B, 8pj0:A, 8pj0:B, 8pj0:C, 8pj0:D, 8qer:A, 8qer:B, 8qm1:A, 8qm1:B, 8r0i:A, 8r0i:B, 8r1v:A, 8r1v:B, 5sn5:A, 5sn6:A, 5sn7:A, 5sn7:B, 5sn8:A, 5sn9:A, 5sna:B, 5snb:A, 5snc:A, 5snd:A, 5snd:B, 5sne:A, 5sne:B, 5snf:A, 5sng:A, 5snh:A, 5snh:B, 5sni:A, 5sni:B, 5snj:A, 5snj:B, 5snk:A, 5snl:B, 5snm:A, 5snn:A, 5snn:B, 5sno:A, 5sno:B, 5snp:A, 5snp:B, 5snq:B, 5sns:B, 5snt:A, 5snu:A, 5snu:B, 5snv:A, 5snv:B, 5snw:A, 5snx:A, 5snx:B, 5sny:A, 5snz:B, 5so0:A, 5so0:B, 5so1:A, 5so1:B, 5so2:A, 5so2:B, 5so3:A, 5so4:A, 5so4:B, 5so5:A, 5so5:B, 5so6:A, 5so7:A, 5so7:B, 5so8:A, 5so8:B, 5so9:B, 5soa:A, 5sob:A, 5sob:B, 5soc:A, 5soc:B, 5sod:A, 5soe:A, 5soe:B, 5sof:A, 5sog:A, 5sog:B, 5soh:A
45 7qh2:C 467 63 0.0407 0.0343 0.2540 4.6 7qh2:F
46 6smp:B 417 40 0.0331 0.0312 0.3250 6.6 6smo:B, 6smo:D, 6smo:F, 6smp:E, 6smp:H, 6smp:K
47 2qo3:B 873 41 0.0305 0.0137 0.2927 7.8 2qo3:A
48 3q86:A 149 44 0.0382 0.1007 0.3409 9.4 3q86:B, 3q89:B, 3q89:E, 3q8u:A, 3q8u:B, 3q8u:C, 3q8u:D, 3q8u:E, 3q8u:F, 3q8v:A, 3q8v:B, 3q8v:D, 3q8y:A, 3q8y:B, 3q8y:C, 3q8y:D, 3q8y:E, 3q8y:F, 3q8y:G, 3q8y:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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