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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SKAAEFVISKVDDLMNWARTGSIWPMTFGLACCAVEMMHTGAARYDLDRFGIIFRPSPRQSDCMIVAGTLTNKMAPALRK
VYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGLLQLQKKINRRKDFLHWWNK

The query sequence (length=157) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8e73:S7 158 157 0.9873 0.9810 0.9873 6.71e-117 7a23:E, 7a24:E, 7aqr:B, 7ar7:B, 7ar8:B, 7arb:B, 8bee:B, 8bpx:B, 8bq5:B, 8bq6:B, 6x89:S7
2 8q0j:B 158 157 0.8025 0.7975 0.8025 6.09e-97 7ak5:B, 7ak6:B, 7b93:B, 8c2s:B, 8ca3:B, 8ca5:B, 7dgq:D, 7dgr:D, 7dgs:D, 7dgz:D, 7dh0:D, 7dkf:D2, 6g2j:B, 6g72:B, 5gpn:a, 5gup:I, 8iao:B, 8iap:B, 8ib4:B, 8ib5:B, 8ib9:B, 8iba:B, 8ibd:B, 8ibe:B, 8ic2:B, 8ic3:B, 5lc5:B, 5ldw:B, 5ldx:B, 5lnk:6, 5o31:B, 8olt:B, 8om1:B, 7psa:B, 8pw5:6, 8pw6:6, 8pw7:6, 8q0a:B, 8q0f:B, 8q0m:B, 8q0o:B, 8q0q:B, 8q1p:B, 8q1u:B, 8q1y:B, 8q25:B, 8q45:B, 8q46:B, 8q47:B, 8q48:B, 8q49:B, 8q4a:B, 6q9d:S7, 6qa9:S7, 6qbx:S7, 6qc2:S7, 6qc3:S7, 6qc4:S7, 6qc5:S7, 6qc6:S7, 6qc7:S7, 6qc8:S7, 6qc9:S7, 6qca:S7, 6qcf:S7, 7qsd:B, 7qsk:B, 7qsl:B, 7qsm:B, 7qsn:B, 7qso:B, 7r41:B, 7r42:B, 7r43:B, 7r44:B, 7r45:B, 7r46:B, 7r47:B, 7r48:B, 7r4c:B, 7r4d:B, 7r4f:B, 7r4g:B, 8rgp:6, 8rgq:6, 8rgr:6, 8rgt:6, 8ud1:1B, 8ueo:1B, 8uep:1B, 8ueq:1B, 8uer:1B, 8ues:1B, 8uet:1B, 8ueu:1B, 8uev:1B, 8uew:1B, 8uex:1B, 8uey:1B, 8uez:1B, 8ugh:1B, 8ugi:1B, 8ugj:1B, 8ugn:1B, 8ugn:5B, 8ugp:1B, 8ugr:1B, 8ugr:5B, 7v2c:C, 7v2d:C, 7v2e:C, 7v2f:C, 7v2h:C, 7v2k:C, 7v2r:C, 7v30:C, 7v31:C, 7v32:C, 7v33:C, 7v3m:C, 7vb7:C, 7vbn:C, 7vbz:C, 7vwj:C, 7vxp:C, 7vxu:C, 7vy8:C, 7vya:C, 7vyf:C, 7vyh:C, 7vyn:C, 7vz1:C, 7vzv:C, 7vzw:C, 7w00:C, 7w0h:C, 7w0r:C, 7w0y:C, 7w1o:C, 7w1p:C, 7w1t:C, 7w1u:C, 7w1v:C, 7w1z:C, 7w20:C, 7w2k:C, 7w2l:C, 7w2r:C, 7w2u:C, 7w2y:C, 7w31:C, 7w32:C, 7w35:C, 7w4c:C, 7w4d:C, 7w4e:C, 7w4f:C, 7w4g:C, 7w4j:C, 7w4k:C, 7w4l:C, 7w4m:C, 7w4n:C, 7w4q:C, 5xtb:C, 5xtd:C, 5xth:C, 5xti:C, 5xti:BC, 7zd6:6, 7zdh:6, 7zdj:6, 7zdm:6, 7zdp:6, 7zeb:6, 6zk9:6, 6zkc:6, 6zkd:6, 6zke:6, 6zkf:6, 6zkg:6, 6zkh:6, 6zki:6, 6zkj:6, 6zkk:6, 6zkl:6, 6zkm:6, 6zkn:6, 6zko:6, 6zkp:6, 6zkq:6, 6zkr:6, 6zks:6, 6zkt:6, 6zku:6, 6zkv:6, 6zr2:B, 6ztq:B
3 8b9z:B 182 157 0.7771 0.6703 0.7771 1.63e-95 8ba0:B, 8esw:S7, 8esz:S7
4 7arc:B 154 154 0.8408 0.8571 0.8571 9.02e-94 7ard:B
5 7o6y:K 177 157 0.7325 0.6497 0.7325 2.13e-88 6gcs:K, 7o71:K, 6rfq:K, 6rfr:K, 6rfs:K, 4wz7:K, 6y79:K, 6yj4:B
6 7zm7:K 182 154 0.7325 0.6319 0.7468 4.65e-88 6h8k:K, 7zmb:K, 7zmg:K
7 8qby:B 148 142 0.7325 0.7770 0.8099 4.32e-85
8 7tgh:S7 162 144 0.6306 0.6111 0.6875 6.90e-81 8b6f:AT, 8bqs:AT, 8gym:s7, 8gym:S7, 8gzu:s7, 8gzu:S7
9 8iuf:S7 201 145 0.6497 0.5075 0.7034 6.25e-76 8j9h:S7, 8j9i:S7, 8j9j:S7
10 7q5y:F 135 132 0.5159 0.6000 0.6136 3.66e-63 7q5y:L, 7q5y:R, 7q5y:X
11 6i0d:6 166 141 0.5096 0.4819 0.5674 1.62e-59 4hea:6, 4hea:G, 6i0d:G, 6i1p:6, 6i1p:G, 3i9v:6, 3i9v:F, 3ias:6, 3ias:F, 3ias:O, 3ias:X, 3m9s:6, 3m9s:F, 6q8o:6, 6q8o:G, 6q8w:6, 6q8w:G, 6q8x:6, 6q8x:G, 6y11:6, 6y11:G, 6ziy:6, 6zjl:6, 6zjn:6, 6zjy:6
12 8e9g:B 183 143 0.4904 0.4208 0.5385 4.14e-56 8e9h:B, 8e9i:B
13 7z7s:B 213 148 0.4968 0.3662 0.5270 4.48e-55 7nyr:B, 7nyu:B, 7nyv:B, 7p61:B, 7p62:B, 7p63:B, 7p64:B, 7p7c:B, 7p7j:B, 7p7k:B, 7p7l:B, 7p7m:B, 7z7r:B, 7z7t:B, 7z7v:B, 7z80:B, 7z83:B, 7z84:B
14 6nbq:K 212 144 0.4395 0.3255 0.4792 3.43e-52 6hum:K, 6khi:K, 6khj:K, 6l7o:K, 6l7p:K, 6nbx:K, 6nby:K, 6tjv:K
15 2fug:6 144 140 0.4395 0.4792 0.4929 1.85e-48 2fug:F, 2fug:O, 2fug:X, 3iam:6, 3iam:F, 2ybb:6
16 7p69:B 169 148 0.4586 0.4260 0.4865 2.91e-48 7nz1:B, 7p7e:B, 7zc5:B, 7zci:B
17 7awt:B 141 128 0.4522 0.5035 0.5547 9.09e-48
18 7wfg:K 167 143 0.4013 0.3772 0.4406 1.04e-43 7wg5:K
19 6u8y:J 177 154 0.3631 0.3220 0.3701 1.99e-33 6u8y:j
20 6cfw:J 143 115 0.2866 0.3147 0.3913 1.35e-29
21 7z0s:G 250 125 0.3567 0.2240 0.4480 1.07e-28 7z0t:G
22 6qgr:G 253 84 0.1210 0.0751 0.2262 7.50e-04 6qgt:G, 6qii:G
23 4omf:G 231 104 0.1720 0.1169 0.2596 0.001 4ci0:B, 3zfs:B
24 8w7y:A 474 64 0.1210 0.0401 0.2969 0.011
25 7t2r:E 179 27 0.0892 0.0782 0.5185 0.040 7t2r:J, 7t30:E, 7t30:J
26 5xf9:C 178 72 0.1338 0.1180 0.2917 0.051 5xf9:G, 5xfa:C, 5xfa:G
27 1l1e:A 272 89 0.1465 0.0846 0.2584 0.12 1l1e:B
28 1tpy:A 285 39 0.0828 0.0456 0.3333 2.6
29 5odc:E 298 26 0.0637 0.0336 0.3846 3.5 5odc:K, 5odh:E, 5odh:K, 5odi:E, 5odi:K, 5odq:E, 5odq:K, 5odr:E, 5odr:K
30 5sup:B 383 28 0.0637 0.0261 0.3571 3.5 5sup:A, 5sup:C, 5suq:A, 5suq:C
31 8eqm:C 453 71 0.1019 0.0353 0.2254 4.6 8eqm:c, 7sa3:C
32 3nzq:A 628 99 0.1720 0.0430 0.2727 5.2 3nzq:B
33 6rm3:LV0 135 86 0.1592 0.1852 0.2907 6.8
34 8iox:A 524 22 0.0573 0.0172 0.4091 8.6 8iox:C, 8iox:D, 8iox:E, 8iox:F, 8iox:G, 8iox:H, 8iox:I, 8iox:J, 8iox:K, 8ip1:A, 8ip1:B
35 2vfa:B 205 84 0.1338 0.1024 0.2500 9.6 2vfa:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218