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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SGIVPTLQNIVATVTLGCRLDLKTVALHARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYA
RIIQKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHGTFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKQR
EEIYQAFEAIYPVLSEFRKM

The query sequence (length=180) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4b0a:A 237 180 0.9944 0.7553 0.9944 1.29e-130
2 6cnb:R 522 180 1.0000 0.3448 1.0000 1.03e-128 8cen:O, 8ceo:O, 6cnc:R, 6cnd:R, 6cnf:R, 6eu0:Y, 6f40:U, 6f41:U, 6f42:U, 6f44:U, 8ffz:H, 5fmf:Q, 5fyw:O, 5fz5:O, 6gyk:O, 6gyl:O, 6gym:O, 7ml0:O, 7ml1:O, 7ml2:O, 7ml4:O, 1ngm:A, 1ngm:E, 1ngm:I, 1ngm:M, 1nh2:A, 7o4i:O, 7o4j:O, 7o72:O, 7o73:O, 7o75:O, 7oh9:K, 7oha:K, 7ohb:K, 5oqj:O, 5oqm:O, 7q5b:Y, 1rm1:A, 5sva:j, 4v1n:O, 4v1o:O, 1ytb:A, 1ytb:B, 1ytf:A, 7z7n:D, 7zb5:D, 7zb5:G, 7zs9:O, 7zsa:O, 7zsb:O
3 6uep:B 191 180 0.8500 0.8010 0.8500 2.88e-112 6njq:B, 6njq:A, 1qn3:A, 1qn3:B, 1qn4:A, 1qn4:B, 1qn5:A, 1qn5:B, 1qn6:A, 1qn6:B, 1qn7:A, 1qn7:B, 1qn8:A, 1qn8:B, 1qn9:A, 1qn9:B, 1qna:A, 1qna:B, 1qnb:A, 1qnb:B, 1qnc:A, 1qnc:B, 1qne:A, 1qne:B, 6ueo:A, 6ueo:D, 6ueo:G, 6ueo:J, 6uep:A, 6ueq:B, 6uer:A, 6uer:B, 1vol:B, 1vtl:E, 1vtl:F, 1vto:A, 1vto:B
4 5iy6:P 185 179 0.8056 0.7838 0.8101 3.79e-109 8bvw:O, 8byq:O, 8bz1:O, 1c9b:B, 1c9b:F, 1c9b:J, 1c9b:N, 1c9b:R, 1cdw:A, 7edx:P, 7eg7:P, 7eg8:P, 7eg9:P, 7ega:P, 7egb:P, 7egc:P, 7egd:P, 7egj:P, 7ena:DP, 7enc:DP, 5fur:A, 8gxq:DP, 8gxs:DP, 8ity:U, 8iue:U, 8iuh:U, 5iy7:P, 5iy8:P, 5iy9:P, 5iya:P, 5iyb:P, 5iyc:P, 5iyd:P, 1jfi:C, 7lbm:P, 6mzm:T, 5n9g:B, 5n9g:G, 1nvp:A, 7nvr:O, 7nvs:O, 7nvt:O, 7nvu:O, 7nvy:O, 7nvz:O, 7nw0:O, 6o9l:P, 4roc:B, 4rod:B, 4roe:B, 8s51:O, 8s52:O, 8s5n:O, 1tgh:A, 8wak:P, 8wal:P, 8wan:P, 8wao:P, 8wap:P, 8waq:P, 8war:P, 8was:P, 7zwc:O, 7zwd:O, 7zx7:O, 7zx8:O, 7zxe:O
5 4wzs:D 178 178 0.7722 0.7809 0.7809 1.38e-104
6 1ais:A 181 174 0.4111 0.4088 0.4253 1.09e-36 1d3u:A
7 5gsn:A 445 71 0.1167 0.0472 0.2958 0.70 5gsn:B, 5gsn:C, 5gsn:D, 5ipy:A, 5ipy:B, 5iq1:A, 5iq1:B, 5iq4:A, 5iq4:B
8 2wlt:A 326 111 0.1444 0.0798 0.2342 1.8 2wt4:A
9 4gyj:A 618 86 0.1500 0.0437 0.3140 3.8 3bmx:A, 3bmx:B, 4gyj:B, 4gyk:A, 3nvd:A, 3nvd:B
10 8a47:C 297 49 0.0889 0.0539 0.3265 4.1
11 1zrm:A 220 29 0.0667 0.0545 0.4138 4.4

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218