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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLAD
NGKACIPTGPYPCGKQTLE

The query sequence (length=99) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1p0s:L 99 99 1.0000 1.0000 1.0000 3.92e-71 2y80:B
2 1xkb:A 91 53 0.5253 0.5714 0.9811 8.47e-34 3k9x:A
3 2vwn:L 44 51 0.4444 1.0000 0.8627 1.11e-23 2vwo:L
4 6r2w:L 143 138 0.4949 0.3427 0.3551 3.02e-23 2a2q:L, 2aei:L, 2aer:L, 2b8o:L, 2c4f:L, 8cn9:D, 8cn9:I, 8cn9:S, 1dan:L, 1dva:L, 1dva:M, 2ec9:L, 3ela:L, 1fak:L, 1ff7:A, 1ffm:A, 2fir:L, 4ibl:L, 1j9c:L, 5l0s:B, 5par:A, 2puq:L, 1qfk:L, 3th2:L, 3th3:L, 3th4:L, 1w0y:L, 1w2k:L, 1wqv:L, 1wss:L, 1wtg:L, 1wun:L, 1wv7:L, 4ylq:L, 1z6j:L, 4z6a:L, 4zma:L, 2zp0:L, 2zwl:L, 2zzu:L
5 1iod:G 44 42 0.3131 0.7045 0.7381 2.18e-17
6 1j34:C 46 40 0.2727 0.5870 0.6750 1.63e-13 1j35:C, 1nl0:G
7 5edm:A 550 42 0.2828 0.0509 0.6667 2.18e-12 5edk:A, 4o03:A
8 6bjr:A 575 42 0.2828 0.0487 0.6667 2.25e-12 2a0q:D, 1a2c:H, 2a2x:H, 5a2m:H, 1a3b:H, 1a3e:H, 1a46:H, 1a4w:H, 2a45:B, 2a45:E, 1a5g:H, 1a61:H, 1abi:H, 1abj:H, 7ac9:H, 1ad8:H, 1ae8:H, 1afe:H, 2afq:B, 2afq:D, 5af9:H, 5afy:H, 5afz:H, 1aht:H, 5ahg:H, 1ai8:H, 1aix:H, 2ank:H, 2anm:H, 8ase:H, 8ase:B, 8asf:H, 8asf:B, 1awf:H, 1awh:B, 1awh:D, 4ax9:H, 1ay6:H, 4ayv:B, 4ayy:B, 4az2:B, 3b23:B, 1b5g:H, 2b5t:B, 2b5t:D, 1b7x:B, 3b9f:H, 1ba8:B, 4bah:B, 4bak:B, 4bam:B, 4ban:B, 4bao:B, 4baq:B, 1bb0:B, 1bcu:H, 2bdy:A, 3bef:A, 3bef:B, 3bef:D, 3bef:E, 3bf6:H, 1bhx:B, 1bhx:F, 3biu:H, 3biv:H, 1bmm:H, 1bmn:H, 4boh:A, 4boh:H, 2bvr:H, 2bvs:H, 2bvx:H, 3bv9:B, 8bw5:H, 2bxt:H, 2bxu:H, 1c1u:H, 1c1v:H, 1c1w:H, 3c1k:A, 3c27:B, 6c2w:A, 6c2w:B, 1c4u:2, 1c4v:2, 1c4y:2, 1c5l:H, 1c5n:H, 1c5o:H, 2c8w:B, 2c8x:B, 2c8y:B, 2c8z:B, 2c90:B, 2c93:B, 1ca8:B, 2cf8:H, 2cf9:H, 4ch2:D, 4ch2:B, 4ch8:B, 4ch8:F, 4ch8:H, 4ch8:D, 5cmx:H, 2cn0:H, 6cym:A, 6cym:C, 1d3d:B, 1d3p:B, 1d3q:B, 1d3t:B, 1d4p:B, 3d49:H, 1d6w:A, 1d9i:A, 3da9:B, 3dd2:H, 1de7:H, 1de7:K, 3dhk:H, 1dit:H, 4dih:H, 4dii:H, 1dm4:B, 1doj:A, 5do4:L, 5do4:H, 3dt0:H, 4dt7:B, 4dt7:D, 3dux:H, 1dwb:H, 1dwc:H, 1dwd:H, 1dwe:H, 1dx5:M, 1dx5:N, 1dx5:O, 1dx5:P, 4dy7:A, 4e05:H, 4e06:H, 3e6p:H, 4e7r:H, 4e7r:G, 5e8e:H, 1eb1:H, 3egk:H, 1eoj:A, 1eol:A, 6eo6:H, 6eo7:H, 6eo8:H, 6eo9:H, 3eq0:H, 6evv:H, 5ew1:H, 5ew2:H, 3f68:H, 2feq:H, 2fes:H, 6fjt:H, 1fpc:H, 1fph:H, 1g30:B, 1g32:B, 1g37:A, 6gbw:H, 2gde:H, 5gds:H, 1ghv:H, 1ghw:H, 1ghx:H, 1ghy:H, 3gic:B, 5gim:B, 1gj4:H, 1gj5:H, 6gn7:H, 6gwe:A, 6gwe:H, 1h8d:H, 1h8i:H, 2h9t:H, 1hag:E, 1hah:H, 1hai:H, 1hao:H, 1hap:H, 3hat:H, 1hbt:H, 1hdt:H, 4hfp:B, 4hfp:D, 1hgt:H, 2hgt:H, 3hkj:B, 3hkj:E, 1hlt:H, 1hlt:K, 2hnt:C, 2hnt:E, 2hnt:F, 2hpp:H, 2hpq:H, 6hsx:H, 1hut:H, 2hwl:B, 2hwl:D, 1hxe:H, 1hxf:H, 6i51:H, 4i7y:H, 1ihs:H, 1iht:H, 5jdu:D, 5jfd:H, 2jh0:D, 2jh5:D, 2jh6:D, 1jou:B, 1jou:D, 1jou:F, 1jwt:A, 3jz2:B, 5jzy:H, 1k21:H, 1k22:H, 7kme:H, 8kme:2, 1kts:B, 1ktt:B, 5l6n:H, 5lce:H, 3ldx:H, 1lhc:H, 1lhd:H, 1lhe:H, 1lhf:H, 1lhg:H, 4loy:H, 5lpd:H, 3lu9:B, 3lu9:E, 4lxb:H, 4lz1:H, 4lz4:B, 4lz4:D, 5mjt:H, 7mj5:E, 7mj5:G, 7mj5:J, 7mj5:M, 7mj5:C, 5mls:H, 5mm6:H, 1mu6:B, 1mu8:B, 1mue:B, 5nhu:H, 5nhu:C, 5nhu:A, 1nm6:A, 1no9:H, 1nrn:H, 1nro:H, 1nrp:H, 1nrq:H, 1nrr:H, 1nrs:H, 1nt1:A, 7ntu:B, 7ntu:D, 1nu7:B, 1nu7:F, 1nu9:A, 1nu9:D, 1ny2:2, 1nzq:H, 1o0d:H, 1o2g:H, 1o5g:H, 2od3:B, 1ook:B, 1oyt:H, 3p17:H, 3p6z:B, 3p6z:H, 3p70:B, 3p70:D, 3p70:F, 3p70:H, 1p8v:C, 2pgq:A, 2pgq:B, 7phx:H, 2pks:B, 2pks:C, 3pmh:B, 3po1:B, 3po1:C, 1ppb:H, 2pw8:H, 6px5:X, 6px5:B, 6pxj:B, 1qbv:H, 3qdz:B, 3qdz:D, 3qgn:B, 1qhr:B, 1qj1:B, 1qj6:B, 1qj7:B, 3qlp:H, 3qto:H, 3qtv:H, 1qur:H, 3qwc:H, 3qx5:H, 2r2m:B, 3r3g:B, 1riw:B, 1riw:C, 4rko:B, 3rlw:H, 3rly:H, 3rm0:H, 3rm2:H, 3rml:H, 3rmm:H, 3rmn:H, 3rmo:H, 4rn6:A, 4rn6:B, 6rot:H, 3s7h:B, 1sb1:H, 1sfq:B, 1sfq:E, 1sg8:B, 1sg8:E, 1sgi:E, 1shh:B, 1shh:E, 3sha:H, 3shc:H, 3si3:H, 3si4:H, 1sl3:A, 3sv2:H, 6t3m:H, 6t3q:H, 1t4u:H, 1t4v:H, 6t4a:H, 3t5f:H, 6t52:H, 6t53:H, 6t54:H, 6t55:H, 6t56:H, 6t57:H, 6t7h:B, 6t7h:H, 6t89:H, 6t8a:H, 1ta2:A, 1ta6:A, 1tb6:H, 1tbz:H, 6tdt:H, 1thp:B, 1thr:H, 1ths:H, 2thf:B, 4thn:H, 6tkg:H, 6tkh:H, 6tki:H, 6tkj:H, 6tkl:H, 1tmb:H, 1tmt:H, 1tmu:H, 1tom:H, 1tq0:D, 1tq7:B, 8tqs:H, 3tu7:H, 1twx:B, 3u8o:H, 3u8r:H, 3u8t:H, 3u98:H, 3u9a:H, 4ud9:H, 4udw:H, 4ue7:H, 4ueh:H, 4ufd:H, 4ufe:H, 4uff:H, 4ufg:H, 1uma:H, 3utu:H, 2uuf:B, 2uuj:B, 2uuk:B, 1uvs:H, 3uwj:H, 2v3h:H, 2v3o:H, 6v64:B, 1vr1:H, 3vxe:H, 3vxf:H, 1vzq:H, 1w7g:H, 1way:B, 1wbg:B, 1xm1:A, 1xmn:F, 1xmn:H, 1xmn:D, 1xmn:B, 6y02:H, 6y9h:H, 6yb6:H, 1ycp:M, 4yes:B, 6yhg:H, 6yhj:H, 6yhj:L, 6ymp:H, 6yn3:H, 1ype:H, 1ypg:H, 1ypj:H, 1ypk:H, 1ypl:H, 1ypm:H, 6yqv:H, 6ysj:H, 6ysx:H, 6z48:H, 6z48:B, 6z48:D, 6z48:F, 1z71:A, 1z8i:B, 1z8j:B, 6z8v:H, 6z8w:H, 6z8x:H, 2zc9:H, 2zda:H, 2zdv:H, 2zf0:H, 2zff:H, 2zfp:H, 2zfq:H, 2zfr:H, 1zgi:A, 1zgv:A, 2zg0:H, 2zgb:H, 2zgx:H, 6zgo:H, 2zhe:H, 2zhf:H, 2zhq:H, 2zhw:H, 2zi2:H, 2ziq:H, 7zkl:H, 7zkm:H, 7zkn:B, 7zkn:D, 7zko:H, 2znk:H, 2zo3:H, 1zrb:A, 6zug:H, 6zuh:H, 6zun:H, 6zuu:H, 6zuw:H, 6zux:H, 6zv7:H, 6zv8:H
9 8eph:A 91 50 0.2525 0.2747 0.5000 1.70e-11 1edm:B, 1edm:C, 8eph:C
10 1nl1:A 147 41 0.2525 0.1701 0.6098 1.80e-10 1nl2:A, 2pf2:A
11 3jtc:C 33 31 0.1818 0.5455 0.5806 2.21e-07 3jtc:D, 1lqv:C, 1lqv:D
12 4bxw:B 287 48 0.2020 0.0697 0.4167 1.08e-06 4bxw:A
13 3h5c:B 312 43 0.1919 0.0609 0.4419 2.54e-04
14 6l6r:A 610 38 0.1414 0.0230 0.3684 0.020 6l6r:B, 7nam:A, 3sob:B, 3soq:A, 3sov:A
15 6l6r:A 610 37 0.1212 0.0197 0.3243 0.024 6l6r:B, 7nam:A, 3sob:B, 3soq:A, 3sov:A
16 5ckn:A 278 33 0.1313 0.0468 0.3939 0.044 5cis:A, 5ckm:A, 5ckn:D, 1nt0:A, 1nt0:G
17 1szb:A 167 62 0.2121 0.1257 0.3387 0.071 1szb:B
18 2qz4:A 223 67 0.1818 0.0807 0.2687 0.13
19 4aqb:A 345 29 0.1111 0.0319 0.3793 0.26 5ckq:A, 3dem:A, 3dem:B
20 4jfa:C 348 31 0.1212 0.0345 0.3871 0.29
21 4j75:A 374 31 0.1212 0.0321 0.3871 0.33 4j75:B, 4jfa:A, 4jfa:B, 4jfa:D
22 3v64:C 338 36 0.1414 0.0414 0.3889 0.36 3v64:D
23 3v64:C 338 36 0.1111 0.0325 0.3056 5.5 3v64:D
24 8xxn:3B 536 44 0.1515 0.0280 0.3409 0.41 6zon:B, 6zp4:B, 6zvj:B
25 8pj1:1 588 32 0.1212 0.0204 0.3750 0.49 6fec:w, 2krb:A, 8oz0:I, 8pj2:1, 8pj3:1, 8pj5:1, 8pj6:1
26 1ktg:A 137 70 0.2323 0.1679 0.3286 1.1 1ktg:B
27 8em4:A 3818 39 0.1313 0.0034 0.3333 1.5 8em4:B
28 8em4:A 3818 40 0.1414 0.0037 0.3500 1.8 8em4:B
29 8em4:A 3818 29 0.1212 0.0031 0.4138 1.9 8em4:B
30 8em4:A 3818 30 0.1111 0.0029 0.3667 2.4 8em4:B
31 8em4:A 3818 35 0.1313 0.0034 0.3714 5.6 8em4:B
32 8em7:A 4378 39 0.1313 0.0030 0.3333 1.8 8em7:B, 8jut:A, 8jut:B, 8juu:B, 8juu:A, 8jx8:B, 8jx8:A, 8jx9:B, 8jxa:A, 8jxb:A, 8jxd:A, 8jxe:A, 8jxe:B, 8jxf:B, 8jxg:A, 8jxh:A, 8jxi:B
33 8em7:A 4378 40 0.1414 0.0032 0.3500 2.2 8em7:B, 8jut:A, 8jut:B, 8juu:B, 8juu:A, 8jx8:B, 8jx8:A, 8jx9:B, 8jxa:A, 8jxb:A, 8jxd:A, 8jxe:A, 8jxe:B, 8jxf:B, 8jxg:A, 8jxh:A, 8jxi:B
34 8em7:A 4378 29 0.1212 0.0027 0.4138 2.3 8em7:B, 8jut:A, 8jut:B, 8juu:B, 8juu:A, 8jx8:B, 8jx8:A, 8jx9:B, 8jxa:A, 8jxb:A, 8jxd:A, 8jxe:A, 8jxe:B, 8jxf:B, 8jxg:A, 8jxh:A, 8jxi:B
35 8em7:A 4378 30 0.1111 0.0025 0.3667 2.8 8em7:B, 8jut:A, 8jut:B, 8juu:B, 8juu:A, 8jx8:B, 8jx8:A, 8jx9:B, 8jxa:A, 8jxb:A, 8jxd:A, 8jxe:A, 8jxe:B, 8jxf:B, 8jxg:A, 8jxh:A, 8jxi:B
36 8em7:A 4378 35 0.1313 0.0030 0.3714 6.4 8em7:B, 8jut:A, 8jut:B, 8juu:B, 8juu:A, 8jx8:B, 8jx8:A, 8jx9:B, 8jxa:A, 8jxb:A, 8jxd:A, 8jxe:A, 8jxe:B, 8jxf:B, 8jxg:A, 8jxh:A, 8jxi:B
37 1irx:B 508 49 0.1717 0.0335 0.3469 2.6 1irx:A
38 1lmj:A 86 27 0.1111 0.1279 0.4074 3.0
39 7nx4:A 348 28 0.1212 0.0345 0.4286 4.0
40 6f1c:A 291 29 0.1010 0.0344 0.3448 4.3 6f1c:C, 6f1d:A, 6f1h:A, 6f1h:C, 6f39:A, 6f39:B
41 4wsi:A 372 87 0.2121 0.0565 0.2414 4.4 7m4r:A, 7ntj:B, 7ntj:A, 7ntk:A, 7ntk:D, 7ntk:B, 7ntk:F, 7qcs:A, 7qcs:B, 4uu5:A, 4wsi:B
42 7xrl:D 554 37 0.1515 0.0271 0.4054 4.4 3auj:A, 3auj:L, 1dio:A, 1dio:L, 1eex:A, 1eex:L, 1egm:A, 1egm:L, 1egv:A, 1egv:L, 1iwb:A, 1iwb:L, 1uc4:A, 1uc4:L, 1uc5:A, 1uc5:L, 7xrk:A, 7xrk:D, 7xrl:A, 5yrt:A, 5yrt:D, 5yrt:G, 5yrt:J, 5yrv:A, 5yrv:D, 5yrv:G, 5yrv:J, 5ysh:A, 5ysh:D, 5ysh:G, 5ysh:J
43 3gcz:A 259 69 0.1919 0.0734 0.2754 6.2
44 7alj:A 115 22 0.1111 0.0957 0.5000 8.0
45 3lmc:A 191 31 0.0909 0.0471 0.2903 8.1
46 6zwm:B 2185 19 0.0808 0.0037 0.4211 8.2 6zwm:A
47 6f1c:D 276 75 0.2222 0.0797 0.2933 9.1 6f1c:B, 6f1h:D, 6f1h:B, 4lmf:A, 4lmf:B, 4lmf:C, 4lmf:D, 4lor:A, 1nzi:A, 1nzi:B
48 2ygk:A 319 13 0.0808 0.0251 0.6154 9.1 2ygk:B
49 3wnk:A 712 39 0.1313 0.0183 0.3333 9.4 3wnl:A, 3wnm:A, 3wnn:A, 3wnn:B, 3wno:A, 3wno:B, 3wnp:A, 3wnp:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218