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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SFDRPEIYSAPVLQGESPNDDDNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSD
EPSDIIPLFETAITQVAKRISILSRAQSANSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLS
IMCRNCRHTTSITINNFNNTVSLPRSCLSTIESESSMANEKNCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRN
LTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKGVAIRTPYIKILGIQSDVVTMFTEEEEEEFLQLSRNPKLYEILTNSIAP
SIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRD
PMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSP
GDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSP
QAAEKLSSNFVTIRKQLLINELESTERPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAAS

The query sequence (length=634) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5bk4:D 661 661 1.0000 0.9592 0.9592 0.0 5bk4:5
2 8p5e:5 695 632 0.9511 0.8676 0.9541 0.0 6eyc:5, 6f0l:D, 6f0l:5, 3ja8:5, 8kg6:5, 8kg8:5, 8kg9:5, 7p30:5, 7p30:D, 7p5z:5, 7p5z:D, 8p62:5, 8p63:5, 7pmk:5, 6ptn:l, 6ptn:5, 6pto:k, 6pto:5, 7pt6:5, 7pt6:E, 7pt7:5, 7pt7:E, 7qhs:5, 6rqc:5, 6skl:5, 6u0m:5, 5u8s:5, 5u8t:5, 7v3u:5, 7v3u:E, 7v3v:5, 7v3v:E, 7w8g:5, 7w8g:E, 8xgc:5, 7z13:5, 7z13:d
3 7pmn:5 660 620 0.9353 0.8985 0.9565 0.0
4 6hv9:5 628 613 0.9054 0.9140 0.9364 0.0
5 8b9a:5 533 609 0.8407 1.0000 0.8752 0.0 8b9b:5, 8b9c:5, 6sko:5
6 8w7m:5 529 617 0.8312 0.9962 0.8541 0.0
7 7pfo:5 605 620 0.5221 0.5471 0.5339 0.0 8b9d:5
8 7w1y:5 710 652 0.5284 0.4718 0.5138 0.0 7plo:5, 7w1y:D
9 6rax:5 620 631 0.5158 0.5274 0.5182 0.0 6ray:5, 6raz:5
10 6xtx:5 577 621 0.4984 0.5477 0.5089 0.0 6xty:5
11 6raw:5 576 617 0.5095 0.5608 0.5235 0.0
12 8ouw:5 541 612 0.4543 0.5323 0.4706 3.08e-179
13 8q6p:5 321 341 0.3360 0.6636 0.6246 3.55e-149
14 4fdg:B 592 625 0.3580 0.3834 0.3632 3.14e-118 8eaf:A, 8eaf:B, 8eaf:C, 8eaf:D, 8eaf:E, 8eaf:F, 8eag:B, 8eag:C, 8eag:D, 8eag:E, 8eag:F, 8eag:A, 8eah:A, 8eah:B, 8eah:C, 8eah:D, 8eah:E, 8eah:F, 8eai:B, 8eai:C, 8eai:D, 8eai:E, 8eai:F, 8eai:A, 8eaj:A, 8eaj:B, 8eaj:C, 8eaj:D, 8eaj:E, 8eaj:F, 8eak:B, 8eak:C, 8eak:D, 8eak:E, 8eak:A, 8eak:F, 8eal:A, 8eal:B, 8eal:C, 8eal:D, 8eal:E, 8eal:F, 8eam:B, 8eam:C, 8eam:D, 8eam:E, 8eam:A, 8eam:F, 4fdg:A, 4fdg:C, 4fdg:D, 4fdg:E, 6mii:A, 6mii:B, 6mii:C, 6mii:D, 6mii:E, 6mii:F, 2vl6:A, 2vl6:B, 2vl6:C, 6wnz:B, 6wnz:A
15 4r7y:A 591 618 0.3407 0.3655 0.3495 2.23e-116 4r7y:B, 4r7z:A, 4r7z:B, 4r7z:C, 4r7z:D, 4r7z:E, 4r7z:F, 4r7z:G, 4r7z:H, 4r7z:I, 4r7z:P, 4r7z:J, 4r7z:K, 4r7z:L, 4r7z:M, 4r7z:N, 4r7z:O
16 8x7u:D 654 615 0.3391 0.3287 0.3496 1.16e-113 8x7u:E, 8x7u:C, 8x7u:B, 8x7u:F, 8x7u:A
17 7pt6:2 629 613 0.3517 0.3545 0.3638 8.36e-113 5bk4:2, 5bk4:A, 6eyc:2, 6f0l:A, 6f0l:2, 3ja8:2, 7p30:2, 7p30:A, 7p5z:2, 7p5z:A, 7pt6:B, 7pt7:2, 7pt7:B, 6rqc:2, 6sko:2, 5u8s:2, 7v3u:2, 7v3u:B, 7v3v:2, 7v3v:B, 5v8f:2, 8w7m:2, 7w8g:2, 7w8g:B
18 8p5e:3 649 638 0.3423 0.3344 0.3401 1.00e-112 8kg6:3, 8kg8:3, 8kg9:3, 8p62:3, 8p63:3, 7pt6:3, 7pt6:C, 7pt7:3, 7qhs:3, 7v3u:3, 7v3u:C, 7v3v:3, 7v3v:C, 7w8g:3, 7w8g:C, 7z13:3, 7z13:b
19 7w1y:4 653 598 0.3391 0.3292 0.3595 2.89e-112 7w1y:C, 6xtx:4, 6xty:4
20 8b9d:4 677 620 0.3549 0.3323 0.3629 1.65e-111 7pfo:4, 7plo:4
21 8w7m:3 619 611 0.3312 0.3393 0.3437 1.83e-110 8b9a:3, 8b9b:3, 8b9c:3, 7pmk:3, 6skl:3, 8xgc:3
22 6rax:4 626 642 0.3533 0.3578 0.3489 5.96e-109 6raw:4, 6ray:4, 6raz:4
23 8xgc:2 778 636 0.3533 0.2879 0.3522 1.33e-108 8kg6:2, 8kg8:2, 8kg9:2, 8p5e:2, 8p62:2, 8p63:2, 7pmk:2, 7pmn:2, 6ptn:i, 6ptn:2, 6pto:h, 6pto:2, 7qhs:2, 6skl:2, 6u0m:2, 7z13:2, 7z13:a
24 8ouw:3 619 516 0.3060 0.3134 0.3760 1.20e-107
25 7pt7:C 633 629 0.3312 0.3318 0.3339 1.43e-106
26 6hv9:3 558 558 0.3155 0.3584 0.3584 2.36e-106
27 6wgi:3 637 597 0.3360 0.3344 0.3568 2.38e-106
28 7plo:3 628 631 0.3375 0.3408 0.3391 1.25e-105 7pfo:3
29 5u8t:2 583 614 0.3375 0.3671 0.3485 1.43e-105
30 6xtx:3 608 598 0.3312 0.3454 0.3512 3.12e-105
31 6raw:6 601 623 0.3423 0.3611 0.3483 5.43e-105 6raz:6
32 5v8f:4 741 667 0.3407 0.2915 0.3238 6.59e-105 5bk4:C, 5bk4:4, 6eyc:4, 6f0l:C, 3ja8:4, 7p30:4, 7p30:C, 7p5z:C, 7p5z:4, 7pt6:4, 7pt6:D, 7pt7:4, 7pt7:D, 6rqc:4, 7v3u:4, 7v3u:D, 7v3v:4, 7v3v:D, 7w8g:4, 7w8g:D
33 8ouw:4 619 589 0.3249 0.3328 0.3497 7.21e-105
34 7w1y:B 651 651 0.3438 0.3349 0.3349 8.59e-104 7w1y:3
35 5v8f:3 654 610 0.3281 0.3180 0.3410 8.80e-104 5bk4:B, 5bk4:3, 6eyc:3, 6f0l:3, 6f0l:B, 3ja8:3, 7p30:3, 7p30:B, 7p5z:3, 7p5z:B, 6ptn:j, 6ptn:3, 6pto:i, 6pto:3, 6rqc:3, 6sko:3, 6u0m:3, 5u8s:3, 5u8t:3
36 8kg8:4 697 640 0.3312 0.3013 0.3281 2.02e-103 8b9a:4, 8b9b:4, 8b9c:4, 8kg6:4, 8p5e:4, 8p62:4, 8p63:4, 7pmk:4, 7pmn:4, 7qhs:4, 6sko:4, 8w7m:4, 7z13:4, 7z13:c
37 8ouw:7 632 641 0.3423 0.3434 0.3385 3.11e-103
38 6rax:2 605 636 0.3312 0.3471 0.3302 1.70e-102 6raw:2, 6ray:2
39 6rax:6 628 643 0.3454 0.3487 0.3406 2.02e-102 6ray:6
40 6ray:3 600 626 0.3438 0.3633 0.3482 6.49e-102 6raw:3, 6raz:3
41 7w1y:2 706 623 0.3312 0.2975 0.3371 2.81e-101 7pfo:2, 7plo:2, 8q6o:A, 8q6o:2, 8q6p:2, 7w1y:A, 6xtx:2, 6xty:2
42 5u8t:6 661 597 0.3186 0.3056 0.3384 7.74e-101 6wgi:6
43 8b9d:3 569 592 0.3297 0.3673 0.3530 9.86e-101
44 6rax:3 625 641 0.3502 0.3552 0.3463 1.75e-100
45 7plo:7 607 626 0.3328 0.3476 0.3371 3.77e-100 7pfo:7
46 6xtx:6 679 622 0.3281 0.3063 0.3344 6.72e-100 8b9d:6, 7pfo:6, 7plo:6, 6xty:6
47 6xtx:7 598 612 0.3265 0.3462 0.3382 2.18e-99 6xty:7
48 7v3u:6 646 638 0.3170 0.3111 0.3150 6.68e-99 7qhs:6, 7v3u:F, 7v3v:6, 7v3v:F, 7w8g:6, 7w8g:F, 7z13:6, 7z13:e
49 8ouw:6 707 649 0.3344 0.2999 0.3267 3.79e-98
50 5v8f:6 692 642 0.3218 0.2948 0.3178 6.03e-98 8b9a:6, 8b9b:6, 8b9c:6, 6eyc:6, 3ja8:6, 8kg6:6, 8kg8:6, 8kg9:6, 7p30:6, 7p30:E, 7p5z:6, 7p5z:E, 8p5e:6, 8p62:6, 8p63:6, 7pmk:6, 7pmn:6, 6ptn:m, 6ptn:6, 6pto:l, 6pto:6, 7pt6:6, 7pt6:F, 7pt7:6, 7pt7:F, 6rqc:6, 6skl:6, 6sko:6, 6u0m:6, 5u8s:6, 8w7m:6, 8xgc:6
51 7w1y:6 716 653 0.3328 0.2947 0.3231 1.94e-97 7w1y:E
52 5v8f:7 725 519 0.3170 0.2772 0.3873 2.20e-97 8b9a:7, 8b9b:7, 8b9c:7, 3jc6:7, 3jc7:7, 8kg6:7, 8kg8:7, 8p5e:7, 8p62:7, 8p63:7, 7pt6:7, 7pt6:G, 7pt7:7, 7pt7:G, 7qhs:7, 6rqc:7, 6sko:7, 8w7m:7, 7z13:7, 7z13:f
53 7v3u:7 699 525 0.3170 0.2876 0.3829 5.33e-97 5bk4:F, 5bk4:7, 6eyc:7, 3ja8:7, 7p30:7, 7p30:F, 7p5z:7, 7p5z:F, 7v3u:G, 7v3v:7, 7v3v:G, 7w8g:7, 7w8g:G
54 6skl:4 679 635 0.3233 0.3019 0.3228 1.68e-96 8kg9:4, 8xgc:4
55 7w1y:F 643 541 0.3044 0.3002 0.3567 1.73e-96 7w1y:7
56 8q6p:3 370 339 0.2445 0.4189 0.4572 1.20e-94
57 6raz:7 601 613 0.3297 0.3478 0.3409 1.34e-94 6ray:7
58 8b9d:7 576 623 0.3312 0.3646 0.3371 1.31e-93
59 6rax:7 632 640 0.3312 0.3323 0.3281 1.33e-93 6raw:7
60 8b9d:2 576 616 0.3233 0.3559 0.3328 3.93e-93
61 6raz:2 559 631 0.3202 0.3631 0.3217 1.86e-92
62 8q6p:6 395 336 0.2366 0.3797 0.4464 3.35e-90
63 8kg9:7 636 505 0.3013 0.3003 0.3782 2.27e-89 7pmk:7, 7pmn:7, 6skl:7, 8xgc:7
64 6hv9:2 549 608 0.3249 0.3752 0.3388 1.44e-83
65 8ouw:2 701 626 0.3123 0.2825 0.3163 4.63e-83
66 8b9a:2 568 424 0.2571 0.2870 0.3844 5.18e-80 8b9b:2, 8b9c:2
67 8b9a:2 568 146 0.0489 0.0546 0.2123 0.59 8b9b:2, 8b9c:2
68 8s91:A 602 622 0.2871 0.3023 0.2926 7.55e-71 7dp3:A, 8s91:B, 8s91:C, 8s94:A, 8s94:C, 8s94:B
69 8q6p:7 298 334 0.2098 0.4463 0.3982 1.09e-68
70 7wi7:B 566 607 0.2792 0.3127 0.2916 4.63e-65
71 8s91:D 621 619 0.2855 0.2915 0.2924 3.99e-64 7dpd:A, 7dpd:B, 8s91:E, 8s91:F, 8s94:D, 8s94:F, 8s94:E
72 7wi7:A 565 622 0.2776 0.3115 0.2830 2.81e-63
73 8q6o:D 256 272 0.1609 0.3984 0.3750 3.25e-57 8q6o:5
74 8q6o:C 258 249 0.1057 0.2597 0.2691 1.21e-19 8q6o:4
75 1ltl:E 242 205 0.0868 0.2273 0.2683 3.53e-14 1ltl:A, 1ltl:B, 1ltl:C, 1ltl:D, 1ltl:F
76 4pof:A 255 252 0.0820 0.2039 0.2063 1.83e-11 5iy0:A, 5iy0:B, 5iy0:C, 5iy0:D, 5iy0:E, 5iy0:F, 4pof:B, 4pof:C, 4pof:D, 4pof:E, 4pof:F, 4pog:A, 4pog:E, 4pog:F, 4pog:K, 4pog:L, 4pog:G, 4pog:H, 4pog:I, 4pog:J, 4pog:B, 4pog:C, 4pog:D, 4ywl:A, 4ywl:B, 4ywl:C, 4ywl:D, 4ywl:E, 4ywl:F, 4ywl:G, 4ywl:H, 4ywl:I, 4ywl:J, 4ywm:A, 4ywm:B, 4ywm:C, 4ywm:D, 4ywm:E, 4ywm:F, 4ywm:G, 4ywm:H, 4ywm:I, 4ywm:J
77 8q6o:E 249 205 0.0631 0.1606 0.1951 4.38e-05 8q6o:6
78 8q6o:F 275 257 0.0883 0.2036 0.2179 8.67e-05 8q6o:7
79 4me3:A 246 137 0.0505 0.1301 0.2336 0.049
80 4qht:C 248 186 0.0647 0.1653 0.2204 0.39 6luf:A, 6luf:B, 6luf:C, 6luf:D, 6luf:E, 6luf:F, 6luf:G, 4qht:A, 4qht:B, 4qht:D, 4qht:E, 4qht:F, 4qht:G
81 7oik:A 4426 117 0.0457 0.0066 0.2479 0.76 7oim:A, 6tax:A, 6tay:A
82 5ntd:G 520 99 0.0442 0.0538 0.2828 1.3 4efd:F, 5nsm:A, 5nsm:B, 5nsm:C, 5nsm:D, 5nsm:E, 5nsm:F, 5nsm:G, 5nsm:H, 5nsm:I, 5nsm:J, 5nsm:K, 5nsm:L, 5nsq:A, 5nsq:B, 5nsq:C, 5nsq:D, 5nsq:E, 5nsq:F, 5ntd:A, 5ntd:B, 5ntd:D, 5ntd:C, 5ntd:E, 5ntd:F, 5ntd:H, 5ntd:I, 5ntd:J, 5ntd:K, 5ntd:L
83 1gjq:A 541 56 0.0268 0.0314 0.3036 2.3 1bl9:A, 1bl9:B, 1gjq:B, 5guw:M, 5guw:N, 1hzu:A, 1hzv:A, 1n15:A, 1n15:B, 1n50:A, 1n50:B, 1n90:A, 1n90:B, 1nir:A, 1nir:B, 1nno:A, 1nno:B, 6tpo:A, 6tsi:A, 6tsi:B
84 3rf6:B 352 39 0.0189 0.0341 0.3077 2.4 3kc2:A, 3rf6:A
85 3kc2:B 319 39 0.0189 0.0376 0.3077 3.0
86 5cq9:B 270 71 0.0252 0.0593 0.2254 4.0
87 8dbr:B 513 41 0.0252 0.0312 0.3902 4.4 8dbp:A, 8dbp:B, 8dbp:C, 8dbq:A, 8dbq:B, 8dbq:C, 8dbr:A, 8dbr:C, 8dbs:A, 8dbs:B, 8dbs:C, 8dbt:A, 8dbt:B, 8dbt:C, 8dbu:A, 8dbu:B, 8dbu:C, 8dbv:A, 8dbv:B, 8dbv:C, 8dbw:A, 8dbw:B, 8dbw:C, 3oaa:A, 3oaa:B, 3oaa:C, 3oaa:I, 3oaa:J, 3oaa:K, 3oaa:Q, 3oaa:R, 3oaa:S, 3oaa:Y, 3oaa:Z, 3oaa:a, 6oqr:C, 6oqr:B, 6oqr:A, 6oqs:C, 6oqs:B, 6oqs:A, 6oqt:C, 6oqt:B, 6oqt:A, 6oqu:C, 6oqu:B, 6oqu:A, 6oqv:C, 6oqv:B, 6oqv:A, 6oqw:C, 6oqw:B, 6oqw:A, 6pqv:C, 6pqv:B, 6pqv:A, 5t4o:A, 5t4o:B, 5t4o:C, 5t4p:A, 5t4p:B, 5t4p:C, 5t4q:A, 5t4q:B, 5t4q:C, 6wnq:C, 6wnq:B, 6wnq:A, 6wnr:C, 6wnr:B, 6wnr:A
88 6pdw:D 299 131 0.0568 0.1204 0.2748 4.9 6pdw:B, 6pdw:C, 6pdw:E, 6pdw:F, 6pdy:F, 6pdy:C, 6pdy:D, 6pdy:E, 6pdy:B, 6pe0:B, 6pe0:C, 6pe0:D, 6pe0:E, 6pe0:F
89 2enx:A 310 127 0.0568 0.1161 0.2835 4.9 2enx:B
90 2r65:A 249 50 0.0331 0.0843 0.4200 5.1 2r65:B, 2r65:C, 2r65:D, 2r65:E
91 2gjs:A 150 73 0.0363 0.1533 0.3151 5.2 2dpx:A, 2dpx:B, 2gjs:B, 3q72:A, 3q72:B, 3q7p:A, 3q7p:B, 3q7q:A, 3q7q:B
92 3v97:A 667 61 0.0268 0.0255 0.2787 5.5 3v8v:A
93 5zns:A 381 66 0.0331 0.0551 0.3182 6.9 5znt:A
94 7r8q:B 389 93 0.0394 0.0643 0.2688 7.2 7r8p:A, 7r8q:A
95 8ca1:B 589 101 0.0379 0.0407 0.2376 8.4 8ca1:A
96 8r64:B 303 185 0.0726 0.1518 0.2486 8.5 8r64:C, 8r64:D, 8r64:E, 8r64:F
97 1um8:A 327 125 0.0505 0.0979 0.2560 8.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218