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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
SAQPPIAAKKPHRVTLGYVEGEDRGPNPMNPPRYREDPYFWMRDDDRKDPAVIEHLNKEKVYFQARSADIAQLRDDIYAE
HISHINEDDMSAPYVYGKYRYYTREVKGKPYKIYCRVFTDKEPGDVAAEEVIIDVNQVAEGKAFCDVMEVKPAPPEHDLV
AFSVDMSGNEVYTIEFKRISDPSQTIADKVSGTNGEIVWGPDHTSLFYVTKDETLRENKVWRHVMGKLQSEDVCLYEEHN
PLFSAFMYKAADTNTLCIGSQSPETAEVHLLDLRKGNAHNTLEIVRPREKGVRYDVQMHGTSHLVILTNEGGAVNHKLLI
APRGQPSDWSHVLVDHSEDVFMESIAVRSNYLVVAGRRAGLTRIWTMMADSQDGVFKAGTGLREVVMEEPIFTVHLVESQ
MLEYEEPTFRMEYSSLATPNTWFDVSPQDHSRTAVKVREVGGGFDAANYKVERRFATAPDQTKIPLSVVYHKDLDMSQPQ
PCMLYGYGSYGLSMDPQFSIQHLPYCDRGMIFAIAHIRGGSELGRAWYEIGAKYLTKRNTFSDFIAAAEFLVNAKLTTPS
QLACEGRSAGGLLMGAVLNMRPDLFKVALAGVPFVDVMTTMCDPSIPLTTGEWEEWGNPNEYKYYDYMLSYSPMDNVRAQ
EYPNIMVQCGLHDPRVAYWEPAKWVSKLRECKTDNNEILLNIDMESGHFSAKDRYKFWKESAIQQAFVCKHLKSTVRLLV
R

The query sequence (length=721) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2xe4:A 721 721 1.0000 1.0000 1.0000 0.0
2 4bp9:A 710 717 0.6089 0.6183 0.6123 0.0 4bp9:B, 4bp9:C, 4bp9:D, 4bp9:E, 4bp9:F
3 7ne7:A 677 707 0.3731 0.3973 0.3805 2.53e-149 7ne4:A, 7ne5:A, 7ob1:A, 7ywp:A
4 3muo:A 684 698 0.2580 0.2719 0.2665 3.47e-48 3iuq:A, 3iur:A, 3ivm:A
5 4amy:A 710 743 0.2566 0.2606 0.2490 2.27e-47 4amz:A, 4an0:A, 4an1:A, 4bcb:A, 4bcc:A, 4bcd:A, 3ddu:A, 1e8m:A, 1e8n:A, 3eq7:A, 3eq8:A, 3eq9:A, 1h2y:A, 1h2z:A, 1o6f:A, 1o6g:A, 1qfm:A, 1qfs:A, 1uoo:A, 1uop:A, 1uoq:A, 2xdw:A
6 6jci:A 704 684 0.2455 0.2514 0.2588 2.56e-47
7 2bkl:B 677 706 0.2427 0.2585 0.2479 6.44e-44 2bkl:A
8 7vgb:A 681 559 0.2011 0.2129 0.2594 1.46e-43 7vgb:B, 7vgc:A
9 5o3w:B 717 720 0.2441 0.2455 0.2444 5.98e-40 5o3u:A, 5o3u:B, 5o3u:C, 5o3u:D, 5o3v:B, 5o3v:A, 5o3w:A, 5o3w:C, 5o3w:D, 5uw3:A, 5uw3:B, 5uw3:C, 5uw5:A, 5uw5:B, 5uw5:C, 5uw6:A, 5uw6:B, 5uw6:C, 5uzw:A, 5uzw:B, 5uzw:C
10 5uw3:D 698 703 0.2344 0.2421 0.2404 7.52e-40 5uw5:D, 5uw6:D, 5uw7:A, 5uw7:B, 5uzw:D
11 5n4b:A 722 738 0.2580 0.2576 0.2520 1.82e-36 5n4b:B, 5n4d:A, 5n4d:B
12 6can:A 616 455 0.1761 0.2062 0.2791 3.14e-35 6can:B, 5t88:A, 5t88:B
13 7zaz:AAA 727 563 0.1872 0.1857 0.2398 2.77e-33 7zaz:BBB, 7zaz:DDD, 7zb0:A, 7zb0:B, 7zb0:C, 7zb0:D, 7zb1:A, 7zb1:B, 7zb1:C, 7zb1:D, 7zb2:CCC, 7zb2:FFF
14 7zaz:CCC 690 558 0.1789 0.1870 0.2312 1.55e-28
15 4q1v:A 707 100 0.0374 0.0382 0.2700 0.016 4q1v:B
16 2dcm:A 662 174 0.0527 0.0574 0.2184 0.12 2eep:A, 2z3z:A
17 6eor:B 805 304 0.0929 0.0832 0.2204 0.57 6qzv:B
18 7ayq:A 808 86 0.0319 0.0285 0.2674 0.66 7a3i:A
19 7svm:A 852 86 0.0319 0.0270 0.2674 0.70 7a3g:B, 7a3g:A, 7a3i:B, 7a3i:C, 7a3j:C, 7a3j:A, 7a3j:B, 7a3k:C, 7a3k:A, 7a3k:B, 7a3l:A, 7a3l:B, 7a3l:C, 7ayq:B, 7ayr:A, 7ayr:B, 6eop:A, 6eop:B, 6eop:C, 6eot:A, 6eot:B, 6eot:D, 6eot:G, 6eot:I, 6eot:K, 6hp8:A, 6hp8:B, 6hp8:C, 7or4:B, 7or4:A, 7oz7:A, 7oz7:B, 6qzw:A, 6qzw:B, 6qzw:C, 7svm:B, 7svm:C, 7svo:A, 7svo:B, 7svo:C, 6trw:A, 6trw:B, 6trw:C, 6trx:B, 6trx:C, 6trx:A
20 4re6:A 577 56 0.0291 0.0364 0.3750 0.93 2hu5:A, 2hu5:B, 2hu7:A, 2hu7:B, 2hu8:A, 2hu8:B, 4re5:A, 4re5:B, 4re6:C, 1ve7:A, 1ve7:B
21 7jn7:A 846 34 0.0222 0.0189 0.4706 0.97 6eor:A, 6eor:C, 6eor:D, 7jn7:D, 6qzv:A, 6qzv:C, 6qzv:D, 7svl:A, 7svl:B, 7svl:C, 7svl:D, 7svn:A, 7svn:B, 7svn:C, 7svn:D, 6x6c:A, 6x6c:D, 7zxs:A, 7zxs:B, 7zxs:C, 7zxs:D
22 1oy0:B 248 31 0.0250 0.0726 0.5806 1.3 1oy0:C, 1oy0:D, 1oy0:E
23 3no5:E 275 35 0.0194 0.0509 0.4000 1.8 3no5:A, 3no5:B, 3no5:C, 3no5:D, 3no5:F
24 8gqm:A 377 56 0.0277 0.0531 0.3571 2.2
25 6y0f:C 722 141 0.0458 0.0457 0.2340 3.7 6y0f:A, 6y0f:B, 6y0f:D
26 8i9z:CD 460 140 0.0458 0.0717 0.2357 4.8 8ia0:CD
27 8pts:A 195 83 0.0333 0.1231 0.2892 5.7 8pts:B
28 1boo:A 282 132 0.0444 0.1135 0.2424 7.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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