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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
RTGRFGPRYGLKIRVRVADVEIKHKKKHKCPVCGFKKLKRAGTGIWMCGHCGYKIAGGCYQPETVAGKAVMKA

The query sequence (length=73) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3cxc:Y 73 73 1.0000 1.0000 1.0000 1.49e-48 1jj2:Y, 1k73:1, 1k8a:1, 1k9m:1, 1kc8:1, 1kd1:1, 1kqs:Y, 1m1k:1, 1m90:1, 1n8r:1, 1nji:1, 3ow2:Y, 1q7y:1, 1q81:1, 1q82:1, 1q86:1, 1qvf:Y, 1qvg:Y, 1w2b:Y
2 1ffk:W 73 72 0.8767 0.8767 0.8889 1.37e-41
3 4v4n:Ai 78 70 0.6164 0.5769 0.6429 4.62e-25 4v6u:Bi
4 6skf:Bg 84 66 0.5890 0.5119 0.6515 7.32e-25 6skg:Bg, 6th6:Bg
5 4v9f:Z 83 72 0.4932 0.4337 0.5000 4.34e-23 3cc2:Z, 3cc4:Z, 3cc7:Z, 3cce:Z, 3ccj:Z, 3ccl:Z, 3ccm:Z, 3ccq:Z, 3ccr:Z, 3ccs:Z, 3ccu:Z, 3ccv:Z, 3cd6:Z, 3cma:Z, 3cme:Z, 3cpw:Y, 3g4s:Z, 3g6e:Z, 3g71:Z, 3i55:Z, 3i56:Z, 2otj:Z, 2otl:Z, 2qa4:Z, 2qex:Z, 1s72:Z, 1vq4:Z, 1vq5:Z, 1vq6:Z, 1vq7:Z, 1vq8:Z, 1vq9:Z, 1vqk:Z, 1vql:Z, 1vqm:Z, 1vqn:Z, 1vqo:Z, 1vqp:Z, 1yhq:Z, 1yi2:Z, 1yij:Z, 1yit:Z, 1yj9:Z, 1yjn:Z, 1yjw:Z
6 5xy3:p 89 65 0.3836 0.3146 0.4308 4.51e-15
7 8c3a:AQ 91 69 0.3699 0.2967 0.3913 3.06e-14 8c3a:CK, 8cq7:AQ, 8cq7:CK, 8cqw:AQ, 8cqw:CK, 8cre:AQ, 8cre:CK, 8oeq:AQ, 8oeq:CK, 7pzy:AQ, 7q08:AQ, 7q0f:AQ, 7q0p:AQ, 7q0r:AQ, 8q5i:AQ
8 6zu5:LPP 81 65 0.3699 0.3333 0.4154 3.11e-14
9 6zj3:L5 90 63 0.3973 0.3222 0.4603 5.32e-14
10 4v6i:Bm 92 69 0.3836 0.3043 0.4058 6.51e-14 8aaf:c, 8agt:c, 8agu:c, 8agv:c, 8agw:c, 8agx:c, 8agz:c, 5apn:p, 5apo:p, 7azy:U, 7b7d:Ll, 8bip:Lp, 8bjq:Lp, 8bn3:Q3, 8bqd:AT, 8bqx:AT, 7bt6:p, 7btb:p, 8ccs:b, 8cdl:b, 8cdr:b, 8ceh:b, 8cf5:b, 8cg8:b, 8cgn:b, 8civ:b, 8cku:b, 8cmj:b, 5dat:Q3, 5dat:q3, 5dc3:Q3, 5dc3:q3, 5dge:Q3, 5dge:q3, 5dgf:Q3, 5dgf:q3, 5dgv:Q3, 5dgv:q3, 8eub:Ap, 8evp:Ap, 8evq:Ap, 8evr:Ap, 8evs:Ap, 8evt:Ap, 8ewb:Ap, 8ewc:Ap, 5fci:Q3, 5fci:q3, 5fcj:Q3, 5fcj:q3, 6ft6:p, 5gak:D, 6gq1:p, 6gqb:p, 6gqv:p, 5h4p:p, 6hd7:D, 8hfr:nY, 6hhq:AQ, 6hhq:DR, 5i4l:Q3, 5i4l:q3, 6i7o:AT, 6i7o:XT, 3j6x:83, 3j6y:83, 3j77:93, 3j78:93, 3jct:p, 5jcs:p, 5juo:UA, 5jup:UA, 5jus:UA, 5jut:UA, 5juu:UA, 8k2d:Lp, 8k82:Lp, 5lyb:Q3, 5lyb:q3, 5m1j:p5, 6m62:p, 5mc6:AT, 5mei:AQ, 5mei:DR, 7mpi:Ap, 7mpj:Ap, 6n8j:p, 6n8k:p, 6n8l:p, 6n8m:R, 6n8n:R, 6n8o:R, 7n8b:Ap, 5ndg:Q3, 5ndg:q3, 5ndv:Q3, 5ndv:q3, 5ndw:Q3, 5ndw:q3, 7nrc:Lr, 7nrd:Lr, 5obm:Q3, 5obm:q3, 7of1:p, 7oh3:p, 7ohq:p, 6oig:p, 5on6:AQ, 5on6:DR, 7osa:eL43, 7osm:eL43, 8p8m:RT, 8p8n:RT, 8p8u:RT, 8pfr:RT, 6q8y:AT, 6qik:m, 6qt0:m, 6qtz:m, 6r84:D, 6r86:D, 6r87:D, 6ri5:m, 7rr5:Lp, 6rzz:m, 6s05:m, 6s47:Ar, 6snt:aa, 6sv4:AT, 6sv4:XT, 6sv4:zT, 6t4q:Lp, 5t62:R, 5t6r:R, 6t7i:Lp, 6t7t:Lp, 6t83:pb, 6t83:aa, 5tbw:AQ, 5tbw:DR, 6tb3:AT, 5tga:Q3, 5tga:q3, 5tgm:Q3, 5tgm:q3, 6tnu:AT, 7too:AL43, 7top:AL43, 7u0h:p, 4u3m:Q3, 4u3m:q3, 4u3n:Q3, 4u3n:q3, 4u3u:Q3, 4u3u:q3, 4u4n:Q3, 4u4n:q3, 4u4o:Q3, 4u4o:q3, 4u4q:Q3, 4u4q:q3, 4u4r:Q3, 4u4r:q3, 4u4u:Q3, 4u4u:q3, 4u4y:Q3, 4u4y:q3, 4u4z:Q3, 4u4z:q3, 4u50:Q3, 4u50:q3, 4u51:Q3, 4u51:q3, 4u52:Q3, 4u52:q3, 4u53:Q3, 4u53:q3, 4u55:Q3, 4u55:q3, 4u56:Q3, 4u56:q3, 4u6f:Q3, 4u6f:q3, 7ug6:p, 7uoo:p, 7uqb:p, 7uqz:p, 7v08:p, 4v4b:B9, 4v7f:k, 4v7h:B9, 4v7r:Bg, 4v7r:Dg, 4v88:Bp, 4v88:Dp, 4v8t:p, 4v91:p, 6woo:p, 6xiq:p, 6xir:p, 8y0u:Lp, 6ylg:p, 6ylh:p, 6yly:p, 7z34:p, 6z6j:Lp, 6z6k:Lp, 7zpq:Bo, 7zrs:Bo, 7zs5:BB, 7zuw:Bo, 7zux:Eo, 7zw0:Ls
11 7a01:I2 91 71 0.3836 0.3077 0.3944 2.32e-13 8a3d:j, 5aj0:Ap, 8b5l:p, 8b6c:p, 9bdl:AL43, 9bdn:AL43, 9bdp:AL43, 7bhp:Lp, 8bhf:c1, 8bpo:o2, 8btk:Bp, 7cpu:Lp, 7cpv:Lp, 4d5y:p, 4d67:p, 6d90:p, 6d9j:p, 9f1b:Bp, 9f1c:Bp, 9f1d:Bp, 7f5s:Lp, 8fkz:LX, 8fl2:LX, 8fl3:LX, 8fl4:LX, 8fl6:LX, 8fl7:LX, 8fl9:LX, 8fla:LX, 8flb:LX, 8flc:LX, 8fld:LX, 8fle:LX, 8flf:LX, 6frk:p, 6ftg:p, 6fti:p, 6ftj:p, 8g5y:Lp, 8g5z:Lp, 8g60:Lp, 8g61:Lp, 8g6j:Lp, 8glp:Lp, 6gz3:Ap, 6gz4:Ap, 6gz5:Ap, 6hcf:p3, 6hcj:p3, 6hcm:p3, 6hcq:p3, 8idt:X, 8idy:X, 8ie3:X, 8ifd:2j, 8ife:2j, 8ine:X, 8inf:X, 8ink:X, 6ip5:2j, 6ip6:2j, 6ip8:2j, 8ipd:X, 8ipx:X, 8ipy:X, 8ir1:X, 8ir3:X, 3j7o:p, 3j7p:p, 3j7q:p, 3j7r:p, 3j92:p, 3jag:p, 3jah:p, 3jai:p, 3jaj:p, 3jan:p, 8jdj:u, 8jdk:u, 8jdl:u, 8jdm:u, 8k2c:Lp, 5lks:Lp, 6lqm:X, 6lsr:X, 6lss:X, 7ls1:j2, 7ls2:j2, 6lu8:X, 5lzs:p, 5lzt:p, 5lzu:p, 5lzv:p, 5lzw:p, 5lzx:p, 5lzy:p, 5lzz:p, 7mdz:p, 6mtb:p, 6mtc:p, 6mtd:p, 6mte:p, 7nfx:p, 7nwg:p3, 7nwh:p, 7nwi:p, 7o7y:Bp, 7o7z:Bp, 7o80:Bp, 7o81:Bp, 7obr:p, 8ohd:Lp, 8oj0:Lp, 8oj5:Lp, 8oj8:Lp, 6ole:q, 6olf:q, 6olg:Ap, 6oli:q, 6olz:Ap, 6om0:q, 6om7:q, 7ow7:j, 7oya:p1, 7oyb:p1, 7oyc:p1, 7oyd:p, 8p2k:Bp, 6p5i:Ap, 6p5j:Ap, 6p5k:Ap, 6p5n:Ap, 8q7z:Bp, 8q87:Bp, 8qfd:p, 7qgg:q, 8qoi:Lp, 7qvp:Lp, 7qvp:Mp, 7qwq:p, 7qwr:p, 7qws:p, 6qzp:Lp, 6r5q:p, 6r6g:p, 6r6p:p, 6r7q:p, 8rjb:p, 8rjc:p, 8rjd:p, 8scb:p, 6sgc:p2, 6swa:n, 5t2c:j, 6t59:p3, 7tm3:p, 7toq:AL43, 7tor:AL43, 7tut:p, 7ucj:p, 7uck:p, 4ug0:Lp, 4ujc:Bp, 4ujd:Ap, 4uje:Cp, 4v5z:Bz, 4v6x:Cp, 6w6l:q, 6xa1:Lp, 7xnx:Lp, 7xny:Lp, 8xsx:Lp, 8xsy:Lp, 8xsz:Lp, 6y0g:Lp, 8y0w:Lp, 8y0x:Lp, 6y2l:Lp, 6y57:Lp, 6y6x:Lp, 8yoo:Lp, 8yop:Lp, 6z6l:Lp, 6z6m:Lp, 6z6n:Lp, 7zjw:Lr, 7zjx:Lr, 6zm7:Lp, 6zme:Lp, 6zmi:Lp, 6zmo:Lp, 6zvk:I2
12 5it7:pp 87 69 0.3562 0.2989 0.3768 3.30e-13 6uz7:Bp
13 8fru:p 93 69 0.3562 0.2796 0.3768 7.91e-13 8br8:Lq, 8brm:Lq, 8bsi:Lq, 8bsj:Lq, 8btd:Lq, 8btr:Lq, 7pwg:p, 7pwo:p2
14 4v6w:Cp 91 71 0.3836 0.3077 0.3944 8.32e-13 6xu6:Cp, 6xu7:Cp, 6xu8:Cp
15 6rm3:LPP 83 66 0.4110 0.3614 0.4545 2.16e-12
16 5xxb:o 90 68 0.3425 0.2778 0.3676 4.35e-12
17 9bh5:Cp 88 68 0.3425 0.2841 0.3676 2.34e-11 9cai:Cp
18 7qep:P3 86 66 0.3973 0.3372 0.4394 2.91e-11
19 5t2a:m 91 68 0.3562 0.2857 0.3824 2.96e-11 8a3w:o, 8a98:o, 6az3:o, 3jcs:m, 8ova:Bo, 8ove:Bo, 8ovj:o, 8rxh:Lo, 8rxx:Lo, 5t5h:o, 4v8m:Bo
20 4v8p:BY 102 73 0.4110 0.2941 0.4110 3.18e-11 4v8p:CY, 4v8p:EY, 4v8p:GY
21 7olc:Lp 91 69 0.3288 0.2637 0.3478 4.10e-11 8ia0:Lp, 7old:Lp, 8oo0:Lp, 8pv1:Lp, 8pv2:Lp, 8pv3:Lp, 8pv4:Lp, 8pv5:Lp, 8pv6:Lp, 8pv7:Lp, 8pv8:Lp, 8pvk:Lp, 8pvl:Lp, 7r81:r1, 7z3n:Lp, 7z3o:Lp
22 4v3p:Lm 92 68 0.3425 0.2717 0.3676 1.58e-10 8azw:a, 8b2l:a3, 8ip8:GB, 8ipa:GB, 8ipb:GB, 8jiv:Cp, 7qiw:q, 7qiz:q, 4v7e:Cp, 1ysh:D
23 8p5d:LPP 87 63 0.3425 0.2874 0.3968 2.77e-10 8p60:LPP, 8p60:KPP, 7qca:LPP
24 8eug:K 90 59 0.3288 0.2667 0.4068 1.83e-09 8eui:K
25 8hku:L37A 65 61 0.3425 0.3846 0.4098 4.12e-08 8hkv:L37A, 8hky:L37A, 8hkz:L37A, 8hl1:L37A, 8hl2:L37A, 8hl3:L37A, 8hl4:L37A, 8hl5:L37A
26 3j79:h 85 73 0.3562 0.3059 0.3562 2.61e-07 3jbn:Ah, 3jbo:Ah, 3jbp:Ah, 8tpu:Ah, 5umd:h
27 8d4a:A 1207 26 0.1370 0.0083 0.3846 0.33 8d4b:A
28 4n0n:A 401 38 0.1781 0.0324 0.3421 0.44 4n0o:A, 4n0o:C, 4n0o:E, 4n0o:G
29 5n5y:I 99 55 0.2466 0.1818 0.3273 0.80 5n5z:I, 5n60:I
30 6sc6:A 365 32 0.1644 0.0329 0.3750 0.97 5edv:A, 5edv:B, 6gzy:A, 6gzy:B, 6kc5:B, 6kc6:A, 6kc6:C, 6kc6:E, 6kc6:G, 6kc6:I, 6kc6:K, 4ljo:A, 4ljp:A, 4ljq:B, 4ljq:C, 4ljq:A, 4ljq:D, 6sc5:A, 6sc7:A, 6sc8:A, 6sc9:A, 7v8f:B, 7v8g:D, 7v8g:C
31 6hlq:I 111 41 0.1781 0.1171 0.3171 1.2 5g5l:I, 6hls:I
32 2r6f:B 879 26 0.1644 0.0137 0.4615 1.6
33 2rsj:A 92 52 0.1918 0.1522 0.2692 1.7 2els:A, 2rut:A, 2rv6:A
34 6knb:B 1120 26 0.1507 0.0098 0.4231 2.9 6knc:B
35 2r6f:A 899 19 0.1096 0.0089 0.4211 3.0
36 5ijl:A 943 45 0.2055 0.0159 0.3333 3.2
37 3uwx:A 945 19 0.1096 0.0085 0.4211 3.3
38 4c2m:I 124 39 0.1644 0.0968 0.3077 3.5 4c2m:X, 4c3h:I, 4c3i:I, 4c3j:I, 6h67:I, 6h68:I, 6hko:I, 6hlr:I, 5lmx:I, 5m3f:I, 5m3m:I, 5m5x:I, 5n61:I, 5oa1:I, 6rqt:I, 6ruo:I, 6rwe:I, 6tps:I, 5w5y:I, 5w64:I, 5w65:I, 5w66:I, 4ym7:AI, 4ym7:BI, 4ym7:CI, 4ym7:DI, 4ym7:EI, 4ym7:FI
39 8ppt:B 1191 45 0.2055 0.0126 0.3333 3.6 8ppu:B, 8ppv:B, 6t8h:B
40 8hky:S27A 54 44 0.2603 0.3519 0.4318 3.7 8hkz:S27A, 8hl1:S27A, 8hl2:S27A, 8hl3:S27A, 8hl4:S27A, 8hl5:S27A, 8wkp:S27A, 8wq2:S27A, 8wq4:S27A
41 3zqj:C 890 30 0.1507 0.0124 0.3667 5.0
42 2hr5:A 170 31 0.1644 0.0706 0.3871 5.2 2hr5:B, 3mps:A, 3mps:B, 3mps:D, 3mps:I, 3mps:F, 3mps:K, 3mps:G, 3mps:H, 1nnq:A, 1nnq:B, 3pwf:A, 3pwf:B, 3pza:A, 3pza:B, 3qvd:A, 3qvd:B, 3qvd:C, 3qvd:D, 3qvd:E, 3qvd:F, 3qvd:G, 3qvd:H
43 4zlh:B 338 31 0.1370 0.0296 0.3226 5.3 8v24:A, 8v24:C, 7wzb:B, 7wzb:A, 4zlh:A
44 8hr5:A 466 44 0.1644 0.0258 0.2727 5.7
45 5nhk:B 132 43 0.2329 0.1288 0.3953 7.2 5nbc:A, 5nbc:B, 5nbc:C, 5nbc:D, 5nhk:A, 5nhk:C, 5nhk:D
46 7ocn:A 690 21 0.1096 0.0116 0.3810 7.6 7ocn:B, 7ocp:A, 7ocp:B, 7ocq:A, 7ocq:B, 7ocr:A, 7ocr:B, 7ocs:A, 7ocs:B, 7ocs:C, 7ocs:D, 7oct:A, 7oct:B, 7ocu:A, 7ocu:B
47 4v15:A 373 22 0.1233 0.0241 0.4091 7.7 4v15:B
48 7vl3:A 707 45 0.1644 0.0170 0.2667 7.7 7vkx:A, 7vkx:B, 7vky:A, 7vky:B, 7vkz:A, 7vkz:B, 7vl0:A, 7vl0:B, 7vl1:A, 7vl1:B, 7vl2:A, 7vl2:B, 7vl3:B, 7vl4:A, 7vl4:B, 7vl5:B, 7vl6:A, 7vl6:B, 7vl7:A, 7vl7:B, 7x87:A, 7x87:B
49 5fjj:A 839 57 0.2055 0.0179 0.2632 8.1 5fjj:B, 5fjj:C, 5fjj:D
50 4eb4:B 301 12 0.1233 0.0299 0.7500 9.4 4e5o:A, 4e5o:B, 4e5o:C, 4e5o:D, 4e5o:E, 4e5o:F, 4eb4:A, 4eb4:C, 4eb4:D, 4ein:A, 4ein:B, 3ejl:C, 3ejl:D, 4ez8:A, 6f6z:A, 6f6z:B, 5fct:A, 5fct:B, 4fgt:A, 4g2o:X, 4g6w:X, 4gd7:A, 6gko:A, 6gko:B, 6gyj:A, 3h9k:A, 3h9k:B, 3h9k:D, 3h9k:E, 3hb8:A, 3hb8:B, 3hb8:C, 3hb8:D, 3hb8:E, 5hs3:A, 5hs3:B, 5hs3:C, 5hs3:D, 5hs3:E, 5hs3:F, 1hvy:A, 1hvy:B, 1hvy:C, 1hvy:D, 1i00:A, 1i00:B, 1ju6:A, 1ju6:B, 1ju6:C, 1ju6:D, 1juj:A, 1juj:B, 1juj:C, 1juj:D, 3ob7:A, 3ob7:B, 3ob7:D, 3ob7:E, 6oju:B, 6oju:A, 6oju:C, 6oju:D, 6ojv:B, 6ojv:A, 6ojv:D, 6ojv:C, 6pf3:A, 6pf3:B, 6pf3:C, 6pf3:D, 6pf4:B, 6pf4:D, 6pf4:A, 6pf4:C, 6pf5:A, 6pf5:B, 6pf5:C, 6pf5:D, 6pf6:B, 6pf6:A, 6pf6:C, 6pf6:D, 6qxg:A, 6qxg:B, 6qxg:C, 6qxh:A, 6qxh:B, 6qxh:C, 6qyq:B, 6qyq:D, 6r2e:A, 6r2e:C, 6r2e:D, 6r2e:B, 6r2e:F, 6r2e:H, 6r2e:E, 6r2e:G, 2rd8:B, 2rda:C, 2rda:D, 2rda:E, 1rts:A, 1rts:B, 2tsr:A, 2tsr:B, 2tsr:C, 2tsr:D, 4up1:A, 4up1:B, 4up1:D, 4up1:C, 5wrn:B, 5wrn:A, 5wrn:C, 5wrn:D, 5wrn:E, 5wrn:F, 5x5d:A, 5x5d:D, 5x5d:B, 5x5d:E, 5x5d:C, 5x5d:F, 5x5q:A, 5x5q:D, 5x5q:B, 5x5q:E, 5x5q:C, 5x5q:F, 5x66:A, 5x66:D, 5x66:B, 5x66:E, 5x66:C, 5x66:F, 5x67:A, 5x67:B, 5x69:A, 5x69:D, 5x69:B, 5x69:E, 5x69:C, 5x69:F, 6y08:A, 6y08:B, 6zxo:A, 6zxo:B, 6zxo:C, 6zxo:D, 6zxo:E, 6zxo:F
51 6m73:A 364 24 0.1096 0.0220 0.3333 9.5 6m74:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218